Compounds > celecoxib

celecoxib and n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide

celecoxib has been researched along with n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide in 50 studies

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (6.00)18.2507
2000's27 (54.00)29.6817
2010's19 (38.00)24.3611
2020's1 (2.00)2.80

Authors

AuthorsStudies
Arimura, A; Hori, Y; Inagaki, M; Jyoyama, H; Kakudo, S; Kato, M; Kawai, S; Kobayashi, M; Koizumi, K; Matsumoto, S; Ohno, K; Ono, T; Suzuki, R; Tsuri, T; Yamada, K; Yasui, K1
Chiou, WF; Lin, SJ; Tsai, WJ; Yang, LM; Yang, TH1
Aparoy, P; Chandramohan Reddy, T; Kalangi, SK; Kumar Reddy, K; Reddanna, P1
Chang, LC; Chen, CS; Cheng, FC; Chern, JW; Huang, CH; Tan, CM; Wang, JP1
Che, H; Kim, HP; Park, H; Tuyen, TN1
Basset, J; Casula, G; Cusimano, MG; Harrak, Y; Plescia, S; Pouplana, R; Pujol, MD; Raffa, D; Rosell, G1
Alvarez, S; Basile, L; Blanco, A; Di Pietro, P; Granata, G; Guccione, S; Muñoz-Fernández, MÁ; Santagati, A1
Abdel-Aziz, M; Abdel-Rahman, IM; Aly, OM; Beshr, EA; Ozadali, K; Tan, OU1
Choi, HE; Choi, MJ; Jin, JH; Kang, SM; Kim, KJ; Kim, M; Lee, JY; Lee, KT; Shin, JS1
Abonia, R; Marín-Ocampo, L; Sepúlveda-Arias, JC; Veloza, LA1
Hamilton, LC; Leach, M; Olbrich, A; Thiemermann, C; Wray, GM1
Hamilton, LC; Mitchell, JA; Tomlinson, AM; Warner, TD1
Wallace, JL1
Chemtob, S; Clyman, RI; Heymann, MA; Lin, E; Roman, C; Takahashi, Y; Tse, MM1
Bhatnagar, A; Bolli, R; Liu, SQ; Shinmura, K; Takano, H; Tang, XL; Wang, Y; Xuan, YT1
Chen, C; Hsu, A; Johnson, AJ; song, X1
Bing, RJ; Ingram, M; Miyataka, M; Rich, KA; Yamamoto, T1
Dunlop, ME; Muggli, EE1
Bhagat, L; Saluja, AK; Singh, VP; Song, AM; Steer, ML; Van Acker, GG1
Bolli, R; Kodani, E; Shinmura, K; Takano, H; Tang, XL; Xuan, YT1
Levitt, RJ; Pollak, M1
Abdel-Hafez, M; Kermouni, A; Lau, DC; Yan, H1
Arnaud, C; Godin-Ribuot, D; Joyeux-Faure, M; Ribuot, C1
Bjorling, DE; Calamon-Dixon, JL; Jerde, TJ; Nakada, SY1
Siddiqui, A; Waris, G1
Ferrario, A; Fisher, AM; Gomer, CJ; Rucker, N1
Fischer, SM; Gee, J; Grossman, HB; Jendiroba, D; Lee, IL; Sabichi, AL1
Adhami, VM; Afaq, F; Malik, A; Mukhtar, H; Pasha, FS; Saleem, M; Sarfaraz, S; Siddiqui, IA; Syed, DN; Zaman, N1
Cheng, Y; Ding, G; Huang, H; Sun, W; Tao, J; Zhang, Y1
Berg, Jv; Kuipers, GK; Lafleur, MV; Slotman, BJ; Sminia, P; Stoter, TR; Wedekind, LE1
Choe, M; Choi, EM; Ha, KS; Han, JA; Kim, H; Kim, JI; Kim, SR; Kim, SS; Kim, YM; Lee, EJ; Park, JH1
Guo, CY; Hu, HL; Liu, J; Wang, XP; Xie, CG; Xu, XF; Yu, YC1
Han, JA; Kim, SR; Lee, ME; Park, JH; Park, JS; Park, SC1
Katono, T; Kawato, T; Kitami, S; Maeno, M; Morita, T; Motohashi, M; Suzuki, N; Tanabe, N; Tanaka, H1
Lei, GF; Liu, CX; Sun, RP; Yang, L; Zhang, HJ1
Bauer, B; Hartz, AM; Miller, DS; Pekcec, A; Potschka, H; Unkrüer, B; Zibell, G1
Clapper, ML; Foreman, JE; Gonzalez, FJ; McGinnis, KS; Peters, JM; Rigas, B; Sorg, JM; Williams, JL1
Fang, JF; Guo, WP; Liu, JP; Wei, HB; Zheng, ZH2
Ferrario, A; Gomer, CJ1
Cerella, C; Chateauvieux, S; Dicato, M; Diederich, M; Ghelfi, J; Henry, E; Schnekenburger, M; Sobolewski, C1
Cerella, C; Dicato, M; Diederich, M; Sobolewski, C1
Bandyopadhyay, SK; Chatterjee, A; Chatterjee, S; Chattopadhyay, S; Das, S; Saha, A1
Cerna, D; Coleman, CN; Falduto, MT; J-Aryankalayil, M; Magnuson, SR; Makinde, AY; Palayoor, ST1
Choi, SS; Han, JA; Jung, YJ; Kim, SR; Kim, WJ; Lee, ME; Lee, S1
Asano, K; Ito, Y; Kim, S; Matsukawa, N; Yamamoto, K; Yamatodani, A1
Borchert, P; Hinz, B; Laufer, S; Linnebacher, M; Ramer, R; Walther, U1
Cai, Y; Chen, S; Feng, X; Gao, S; Huang, X; Li, H; Li, Q; Liu, P; Liu, Z; Lu, J; Ye, J1
Kim, HS; Lee, BM; Lim, JS; Park, Y; Yoon, S1
Geddis, AV; Kolb, AL; Matheny, RW; Roberts, BM1

Reviews

2 review(s) available for celecoxib and n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide

ArticleYear
Anti-inflammatory activity of triazine derivatives: A systematic review.
    European journal of medicinal chemistry, 2019, Jan-15, Volume: 162

    Topics: Animals; Anti-Inflammatory Agents; Humans; Inflammation; Structure-Activity Relationship; Triazines

2019
Distribution and expression of cyclooxygenase (COX) isoenzymes, their physiological roles, and the categorization of nonsteroidal anti-inflammatory drugs (NSAIDs).
    The American journal of medicine, 1999, Dec-13, Volume: 107, Issue:6A

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Controlled Clinical Trials as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Etodolac; Gene Expression; Humans; Ibuprofen; Indomethacin; Isoenzymes; Meloxicam; Membrane Proteins; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Thiazines; Thiazoles

1999

Other Studies

48 other study(ies) available for celecoxib and n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide

ArticleYear
Novel antiarthritic agents with 1,2-isothiazolidine-1,1-dioxide (gamma-sultam) skeleton: cytokine suppressive dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase.
    Journal of medicinal chemistry, 2000, May-18, Volume: 43, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experimental; Blood Platelets; Cyclic S-Oxides; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Female; Gastric Mucosa; Humans; Interleukin-1; Isoenzymes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Structure-Activity Relationship; Synovial Membrane; Thiazoles

2000
Selective COX-2 inhibitors. Part 2: synthesis and biological evaluation of 4-benzylideneamino- and 4-phenyliminomethyl-benzenesulfonamides.
    Bioorganic & medicinal chemistry, 2008, Mar-01, Volume: 16, Issue:5

    Topics: Amination; Benzenesulfonamides; Benzylidene Compounds; Blood Platelets; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Imines; Methylation; Molecular Structure; Structure-Activity Relationship; Sulfonamides

2008
Pharmacophore modeling and virtual screening for designing potential 5-lipoxygenase inhibitors.
    Bioorganic & medicinal chemistry letters, 2010, Feb-01, Volume: 20, Issue:3

    Topics: Arachidonate 5-Lipoxygenase; Computer Simulation; Drug Design; Drug Evaluation, Preclinical; Lipoxygenase Inhibitors; Models, Chemical; Models, Molecular

2010
Discovery of 3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide as a novel dual cyclooxygenase/5-lipoxygenase inhibitor that also inhibits tumor necrosis factor-alpha production.
    Bioorganic & medicinal chemistry, 2010, Jan-15, Volume: 18, Issue:2

    Topics: Animals; Benzothiazoles; Cell Line; Crystallography, X-Ray; Cyclic S-Oxides; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Discovery; Humans; Lipoxygenase Inhibitors; Mice; Models, Molecular; Molecular Structure; Nitro Compounds; Structure-Activity Relationship; Thiazoles; Tumor Necrosis Factor-alpha

2010
1,5-Diarylimidazoles with strong inhibitory activity against COX-2 catalyzed PGE2 production from LPS-induced RAW 264.7 cells.
    Bioorganic & medicinal chemistry letters, 2010, Jul-15, Volume: 20, Issue:14

    Topics: Animals; Catalysis; Cell Line; Cyclooxygenase 2 Inhibitors; Dinoprostone; Imidazoles; Lipopolysaccharides; Macrophages; Mice

2010
Synthesis, anti-inflammatory activity, and in vitro antitumor effect of a novel class of cyclooxygenase inhibitors: 4-(aryloyl)phenyl methyl sulfones.
    Journal of medicinal chemistry, 2010, Sep-23, Volume: 53, Issue:18

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Screening Assays, Antitumor; Humans; Hydrophobic and Hydrophilic Interactions; Indoles; Models, Molecular; Rats; Stereoisomerism; Structure-Activity Relationship; Sulfones; Thermodynamics

2010
Sulfonilamidothiopyrimidone and thiopyrimidone derivatives as selective COX-2 inhibitors: synthesis, biological evaluation, and docking studies.
    European journal of medicinal chemistry, 2012, Volume: 57

    Topics: Blotting, Western; Bromodeoxyuridine; Catalytic Domain; Cell Death; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Humans; Interleukin-2; Leukocytes, Mononuclear; Molecular Docking Simulation; Pyrimidinones; Structure-Activity Relationship; Sulfonamides; Thermodynamics; Thiadiazoles

2012
1-(4-Methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazole-3-carboxamides: synthesis, molecular modeling, evaluation of their anti-inflammatory activity and ulcerogenicity.
    European journal of medicinal chemistry, 2014, Apr-22, Volume: 77

    Topics: Animals; Anisoles; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Edema; Hydrazines; Male; Models, Molecular; Molecular Structure; Rats; Stomach Ulcer; Structure-Activity Relationship; Triazoles

2014
Synthesis, biological evaluation, and docking analysis of a novel family of 1-methyl-1H-pyrrole-2,5-diones as highly potent and selective cyclooxygenase-2 (COX-2) inhibitors.
    Bioorganic & medicinal chemistry letters, 2014, Apr-15, Volume: 24, Issue:8

    Topics: Anti-Inflammatory Agents; Benzoquinones; Binding Sites; Catalytic Domain; Cell Survival; Cells, Cultured; Cyclooxygenase 2 Inhibitors; Hydrogen Bonding; Inhibitory Concentration 50; Macrophages; Models, Molecular; Molecular Docking Simulation; Protein Binding; Pyrroles; Structure-Activity Relationship

2014
Effects of inhibitors of the activity of cyclo-oxygenase-2 on the hypotension and multiple organ dysfunction caused by endotoxin: a comparison with dexamethasone.
    British journal of pharmacology, 1998, Volume: 124, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Endotoxemia; Endotoxins; Hypotension; Isoenzymes; Male; Multiple Organ Failure; Nitrates; Nitrites; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Sulfonamides

1998
Synergy between cyclo-oxygenase-2 induction and arachidonic acid supply in vivo: consequences for nonsteroidal antiinflammatory drug efficacy.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1999, Volume: 13, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Antagonism; Drug Synergism; Enzyme Induction; Humans; Inflammation; Isoenzymes; Lipopolysaccharides; Male; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; Sulfonamides

1999
Cyclooxygenase-2 inhibitors constrict the fetal lamb ductus arteriosus both in vitro and in vivo.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 278, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Ductus Arteriosus; Epoprostenol; Female; Hemodynamics; In Vitro Techniques; Indomethacin; Isoenzymes; Nitrobenzenes; Nitroprusside; Oxygen; Pregnancy; Prostaglandin-Endoperoxide Synthases; Pulmonary Artery; Pyrazoles; Sheep; Sulfonamides; Vasoconstriction; Vasodilator Agents

2000
Cyclooxygenase-2 mediates the cardioprotective effects of the late phase of ischemic preconditioning in conscious rabbits.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Aug-29, Volume: 97, Issue:18

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Gene Expression Regulation, Enzymologic; Ischemic Preconditioning; Isoenzymes; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Stunning; Myocardium; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Pyrazoles; Rabbits; Sulfonamides; Transcription, Genetic

2000
Apoptosis signaling pathways mediated by cyclooxygenase-2 inhibitors in prostate cancer cells.
    Advances in enzyme regulation, 2001, Volume: 41

    Topics: Apoptosis; Calcium; Celecoxib; Cell Cycle; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Humans; Isoenzymes; Lactones; Male; Membrane Proteins; Models, Chemical; Nitrobenzenes; Phosphatidylinositol 3-Kinases; Prostaglandin-Endoperoxide Synthases; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Pyrazoles; Signal Transduction; Sulfonamides; Sulfones; Thiophenes; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2001
Nitric oxide, anti-inflammatory drugs on renal prostaglandins and cyclooxygenase-2.
    Hypertension (Dallas, Tex. : 1979), 2002, Mar-01, Volume: 39, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Kidney; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins F; Pyrazoles; Rabbits; Salicylates; Sulfonamides; Thromboxane B2

2002
Hyaluronan increases glomerular cyclooxygenase-2 protein expression in a p38 MAP-kinase-dependent process.
    Kidney international, 2002, Volume: 61, Issue:5

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Activation; Hyaluronic Acid; Isoenzymes; Kidney Glomerulus; Mitogen-Activated Protein Kinases; Nitrobenzenes; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides

2002
Inhibition of cyclooxygenase-2 ameliorates the severity of pancreatitis and associated lung injury.
    American journal of physiology. Gastrointestinal and liver physiology, 2002, Volume: 283, Issue:5

    Topics: Animals; Celecoxib; Ceruletide; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; HSP70 Heat-Shock Proteins; Isoenzymes; Lung Diseases; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzenes; Pancreatitis; Prostaglandin-Endoperoxide Synthases; Pyrazoles; RNA, Messenger; Severity of Illness Index; Sulfonamides; Trypsinogen

2002
Delta-opioid receptor-induced late preconditioning is mediated by cyclooxygenase-2 in conscious rabbits.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzamides; Benzylidene Compounds; Celecoxib; Consciousness; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Heart Rate; Ischemic Preconditioning, Myocardial; Isoenzymes; Male; Myocardial Infarction; Myocardial Stunning; Myocardium; Naltrexone; Narcotic Antagonists; Nitrobenzenes; Piperazines; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rabbits; Receptors, Opioid, delta; Sulfonamides

2002
Insulin-like growth factor-I antagonizes the antiproliferative effects of cyclooxygenase-2 inhibitors on BxPC-3 pancreatic cancer cells.
    Cancer research, 2002, Dec-15, Volume: 62, Issue:24

    Topics: Antineoplastic Agents; Apoptosis; Celecoxib; Cell Cycle; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Interactions; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Isoenzymes; Membrane Proteins; Nitrobenzenes; Pancreatic Neoplasms; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrazoles; Sulfonamides; Tumor Cells, Cultured

2002
Role of cyclooxygenases COX-1 and COX-2 in modulating adipogenesis in 3T3-L1 cells.
    Journal of lipid research, 2003, Volume: 44, Issue:2

    Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Animals; Celecoxib; Cell Differentiation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Gene Expression Regulation, Enzymologic; Glucocorticoids; Isoenzymes; Membrane Proteins; Mice; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Time Factors

2003
COX-2: an in vivo evidence of its participation in heat stress-induced myocardial preconditioning.
    Cardiovascular research, 2003, Jun-01, Volume: 58, Issue:3

    Topics: Animals; Blotting, Western; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Hot Temperature; Ischemic Preconditioning, Myocardial; Isoenzymes; Male; Myocardial Ischemia; Myocardium; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; Sulfonamides

2003
Celecoxib inhibits ureteral contractility and prostanoid release.
    Urology, 2005, Volume: 65, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Celecoxib; Cyclooxygenase Inhibitors; Depression, Chemical; Dimethyl Sulfoxide; Dinoprost; Dinoprostone; Gas Chromatography-Mass Spectrometry; Humans; Indomethacin; Muscle Contraction; Nitrobenzenes; Prostaglandin Antagonists; Prostaglandin D2; Prostaglandins; Pyrazoles; Secretory Rate; Sulfonamides; Sus scrofa; Thromboxane A2; Tumor Necrosis Factor-alpha; Ureter; Ureteral Obstruction

2005
Hepatitis C virus stimulates the expression of cyclooxygenase-2 via oxidative stress: role of prostaglandin E2 in RNA replication.
    Journal of virology, 2005, Volume: 79, Issue:15

    Topics: Celecoxib; Cell Line, Tumor; Chelating Agents; Cyclooxygenase 2; Dinoprostone; Glycoproteins; Hepacivirus; Humans; Membrane Proteins; NF-kappa B; Nitrobenzenes; Oxidative Stress; Phosphatidylinositol 3-Kinases; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Pyrrolidines; Reactive Oxygen Species; Replicon; RNA, Viral; Sulfonamides; Thiocarbamates

2005
Celecoxib and NS-398 enhance photodynamic therapy by increasing in vitro apoptosis and decreasing in vivo inflammatory and angiogenic factors.
    Cancer research, 2005, Oct-15, Volume: 65, Issue:20

    Topics: Animals; Apoptosis; Celecoxib; Cyclooxygenase Inhibitors; Dihematoporphyrin Ether; Dinoprostone; Drug Synergism; Inflammation; Interleukin-1; Interleukin-10; Mammary Neoplasms, Experimental; Mice; Neovascularization, Pathologic; Nitrobenzenes; Photochemotherapy; Photosensitizing Agents; Pyrazoles; Sulfonamides; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2005
Selective cyclooxygenase-2 inhibitors inhibit growth and induce apoptosis of bladder cancer.
    Oncology reports, 2006, Volume: 15, Issue:2

    Topics: Apoptosis; Blotting, Western; Carcinoma, Transitional Cell; Celecoxib; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Down-Regulation; Flow Cytometry; Humans; Nitrobenzenes; Proto-Oncogene Proteins c-bcl-2; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Urinary Bladder Neoplasms

2006
Combined inhibitory effects of green tea polyphenols and selective cyclooxygenase-2 inhibitors on the growth of human prostate cancer cells both in vitro and in vivo.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Mar-01, Volume: 13, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Beverages; Blotting, Western; Celecoxib; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2 Inhibitors; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Flavonoids; Humans; Male; Mice; Mice, Nude; Nitrobenzenes; Phenols; Polyphenols; Prostatic Neoplasms; Pyrazoles; Sulfonamides; Tea

2007
Effects of celecoxib on voltage-gated calcium channel currents in rat pheochromocytoma (PC12) cells.
    Pharmacological research, 2007, Volume: 56, Issue:3

    Topics: Adrenal Gland Neoplasms; Animals; Antineoplastic Agents; Barium; Calcium Channel Blockers; Calcium Channels, L-Type; Celecoxib; Cell Proliferation; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Isoquinolines; Lactones; Membrane Potentials; Nifedipine; Nitrobenzenes; omega-Agatoxin IVA; omega-Conotoxin GVIA; PC12 Cells; Pheochromocytoma; Protein Kinase Inhibitors; Pyrazoles; Rats; Spider Venoms; Sulfonamides; Sulfones

2007
Radiosensitization of human glioma cells by cyclooxygenase-2 (COX-2) inhibition: independent on COX-2 expression and dependent on the COX-2 inhibitor and sequence of administration.
    International journal of radiation biology, 2007, Volume: 83, Issue:10

    Topics: Celecoxib; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Radiation; Flow Cytometry; Gene Expression Regulation, Neoplastic; Glioma; Humans; Meloxicam; Neoplasms; Nitrobenzenes; Pyrazoles; Radiation-Protective Agents; Sulfonamides; Thiazines; Thiazoles

2007
Cyclooxygenase-2 promotes cell proliferation, migration and invasion in U2OS human osteosarcoma cells.
    Experimental & molecular medicine, 2007, Aug-31, Volume: 39, Issue:4

    Topics: Bone Neoplasms; Celecoxib; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Enzyme Activation; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Nitrobenzenes; Osteosarcoma; Pyrazoles; Sulfonamides

2007
Selective inhibition of cyclooxygenase-2 suppresses the growth of pancreatic cancer cells in vitro and in vivo.
    The Tohoku journal of experimental medicine, 2008, Volume: 215, Issue:2

    Topics: Administration, Oral; Aged; Animals; Celecoxib; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Female; Humans; Immunohistochemistry; In Vitro Techniques; Male; Mice; Mice, Nude; Middle Aged; Nitrobenzenes; Pancreatic Neoplasms; Proliferating Cell Nuclear Antigen; Pyrazoles; Radioligand Assay; Sulfonamides; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays

2008
Selective COX-2 inhibitors modulate cellular senescence in human dermal fibroblasts in a catalytic activity-independent manner.
    Mechanisms of ageing and development, 2008, Volume: 129, Issue:12

    Topics: Aspirin; Caveolin 1; Celecoxib; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Fibroblasts; Flurbiprofen; Humans; Ibuprofen; Kinetics; Models, Biological; NF-kappa B; Nitrobenzenes; Pyrazoles; Reactive Oxygen Species; Skin; Skin Aging; Sulfonamides; Tumor Suppressor Protein p53

2008
Effects of nicotine and lipopolysaccharide on the expression of matrix metalloproteinases, plasminogen activators, and their inhibitors in human osteoblasts.
    Archives of oral biology, 2009, Volume: 54, Issue:2

    Topics: Alkaline Phosphatase; Celecoxib; Cell Proliferation; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Gene Expression Regulation; Humans; Lipopolysaccharides; Matrix Metalloproteinase 1; Matrix Metalloproteinases; Nicotine; Nicotinic Antagonists; Nitrobenzenes; Osteoblasts; Plasminogen Activators; Plasminogen Inactivators; Polymyxin B; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Tubocurarine

2009
Cyclooxygenase-2 inhibitor inhibits hippocampal synaptic reorganization in pilocarpine-induced status epilepticus rats.
    Journal of Zhejiang University. Science. B, 2008, Volume: 9, Issue:11

    Topics: Animals; Blotting, Western; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Fibrocystic Breast Disease; Hippocampus; Immunohistochemistry; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Nitrobenzenes; Pilocarpine; Proto-Oncogene Proteins c-fos; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Status Epilepticus; Sulfonamides; Synapses

2008
Prevention of seizure-induced up-regulation of endothelial P-glycoprotein by COX-2 inhibition.
    Neuropharmacology, 2009, Volume: 56, Issue:5

    Topics: Animals; Arachidonic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Capillaries; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Glutamic Acid; In Vitro Techniques; Male; Nitrobenzenes; Protein Transport; Pyrazoles; Rats; Rats, Sprague-Dawley; Status Epilepticus; Sulfonamides; Up-Regulation

2009
Regulation of peroxisome proliferator-activated receptor-beta/delta by the APC/beta-CATENIN pathway and nonsteroidal antiinflammatory drugs.
    Molecular carcinogenesis, 2009, Volume: 48, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; beta Catenin; Blotting, Western; Celecoxib; Colonic Neoplasms; Colonic Polyps; Disease Models, Animal; Female; Genes, APC; Humans; Indomethacin; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrobenzenes; PPAR delta; PPAR-beta; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Tumor Cells, Cultured

2009
Celecoxib increases retinoid sensitivity in human colon cancer cell lines.
    Cellular & molecular biology letters, 2010, Volume: 15, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Celecoxib; Cell Line, Tumor; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Dinoprostone; HT29 Cells; Humans; Nitrobenzenes; Pyrazoles; Receptors, Retinoic Acid; Sulfonamides; Tretinoin

2010
Targeting the tumor microenvironment using photodynamic therapy combined with inhibitors of cyclooxygenase-2 or vascular endothelial growth factor.
    Methods in molecular biology (Clifton, N.J.), 2010, Volume: 635

    Topics: Animals; Celecoxib; Cell Line, Tumor; Cell Transformation, Neoplastic; Combined Modality Therapy; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dihematoporphyrin Ether; Dinoprostone; Female; Humans; Injections; Light; Mice; Neoplasms; Nitrobenzenes; Photochemotherapy; Pyrazoles; Skin; Sulfonamides; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2010
[Celecoxib increased cellular ATRA sensitivity of human colon cancer cell lines through COX-2-independent mechanisms].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2009, Volume: 44, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Celecoxib; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Drug Synergism; HT29 Cells; Humans; Nitrobenzenes; Pyrazoles; Receptors, Retinoic Acid; Sulfonamides; Tretinoin

2009
COX-2 inhibitors block chemotherapeutic agent-induced apoptosis prior to commitment in hematopoietic cancer cells.
    Biochemical pharmacology, 2011, Nov-15, Volume: 82, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Celecoxib; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; DNA Damage; Dose-Response Relationship, Drug; Hematologic Neoplasms; Humans; K562 Cells; Nitrobenzenes; Pyrazoles; Signal Transduction; Stress, Physiological; Sulfonamides; U937 Cells

2011
Cox-2 inhibitors induce early c-Myc downregulation and lead to expression of differentiation markers in leukemia cells.
    Cell cycle (Georgetown, Tex.), 2011, Sep-01, Volume: 10, Issue:17

    Topics: Antigens, Differentiation; Apoptosis; Biomarkers; Celecoxib; Cell Differentiation; Cell Proliferation; Cell Survival; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Down-Regulation; Gene Expression Regulation, Leukemic; Humans; Interphase; Jurkat Cells; K562 Cells; Nitrobenzenes; p38 Mitogen-Activated Protein Kinases; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-myc; Pyrazoles; Sulfonamides; U937 Cells; Up-Regulation

2011
Ellagic acid facilitates indomethacin-induced gastric ulcer healing via COX-2 up-regulation.
    Acta biochimica et biophysica Sinica, 2012, Volume: 44, Issue:7

    Topics: Animals; Blotting, Western; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cytokines; Dinoprostone; Dose-Response Relationship, Drug; Ellagic Acid; Enzyme-Linked Immunosorbent Assay; Gastric Mucosa; Indomethacin; Intercellular Signaling Peptides and Proteins; Male; Mice; Molecular Structure; Nitrobenzenes; Peroxidase; Pyrazoles; Stomach Ulcer; Sulfonamides; Time Factors; Up-Regulation; Wound Healing

2012
Gene expression profile of coronary artery cells treated with nonsteroidal anti-inflammatory drugs reveals off-target effects.
    Journal of cardiovascular pharmacology, 2012, Volume: 59, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Celecoxib; Cell Proliferation; Cells, Cultured; Coronary Vessels; Dose-Response Relationship, Drug; Endothelial Cells; Gene Expression Profiling; Gene Expression Regulation; Humans; Ibuprofen; Microarray Analysis; Molecular Targeted Therapy; Muscle, Smooth, Vascular; Nitrobenzenes; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides

2012
Cyclooxygenase-2 inhibitors modulate skin aging in a catalytic activity-independent manner.
    Experimental & molecular medicine, 2012, Sep-30, Volume: 44, Issue:9

    Topics: Animals; Aspirin; Catalysis; Caveolin 1; Celecoxib; Collagen Type I; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Gene Expression Regulation; Mice; Nitrobenzenes; Pyrazoles; Skin Aging; Sulfonamides; Tumor Suppressor Protein p53

2012
Involvement of hypothalamic cyclooxygenase-2, interleukin-1β and melanocortin in the development of docetaxel-induced anorexia in rats.
    Toxicology, 2012, Dec-16, Volume: 302, Issue:2-3

    Topics: Animals; Anorexia; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Docetaxel; Hypothalamus; Indomethacin; Interleukin-1beta; Male; Neoplasms; Nitrobenzenes; Pro-Opiomelanocortin; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Taxoids

2012
Induction but not inhibition of COX-2 confers human lung cancer cell apoptosis by celecoxib.
    Journal of lipid research, 2013, Volume: 54, Issue:11

    Topics: Anilides; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Celecoxib; Cell Line, Tumor; Cell Nucleus; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Enzyme Induction; Gene Expression Regulation, Neoplastic; Humans; Intracellular Space; Lung Neoplasms; Nitrobenzenes; PPAR gamma; Prostaglandins; Protein Transport; Pyrazoles; Sulfonamides

2013
COX-2 is involved in ET-1-induced hypertrophy of neonatal rat cardiomyocytes: role of NFATc3.
    Molecular and cellular endocrinology, 2014, Feb-15, Volume: 382, Issue:2

    Topics: Animals; Animals, Newborn; Calcineurin; Cardiomegaly; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclosporine; Dinoprostone; Endothelin-1; Gene Expression Regulation; Myocytes, Cardiac; Natriuretic Peptide, Brain; NFATC Transcription Factors; Nitrobenzenes; Primary Cell Culture; Promoter Regions, Genetic; Protein Binding; Pyrazoles; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Sulfonamides; Transcription, Genetic

2014
Co-treatment with Celecoxib or NS398 Strongly Sensitizes Resistant Cancer Cells to Antimitotic Drugs Independent of P-gp Inhibition.
    Anticancer research, 2016, Volume: 36, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimitotic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Celecoxib; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; Drug Resistance, Neoplasm; Drug Synergism; Humans; Nitrobenzenes; Paclitaxel; Sulfonamides; Vinblastine

2016
Celecoxib impairs primary human myoblast proliferation and differentiation independent of cyclooxygenase 2 inhibition.
    Physiological reports, 2022, Volume: 10, Issue:21

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cell Differentiation; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Myoblasts, Skeletal

2022