celecoxib and eflornithine

celecoxib has been researched along with eflornithine in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	6 (54.55)	29.6817
2010's	4 (36.36)	24.3611
2020's	1 (9.09)	2.80

Authors

Authors	Studies
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Aldaz, CM; Conti, CJ; Fischer, SM; Lubet, RA; Viner, J	1
Li, Y; Lubet, RA; Pereira, MA; Steele, VE; Tao, L; Umar, A; Wang, W	1
Lynch, PM	2
Tuma, R	1
Besselsen, DG; Blohm-Mangone, KA; Cui, H; Gerner, EW; Ignatenko, NA; Stringer, DE	1
Bulow, S; Burke, CA; Clark, S; Half, E; Hasson, H; Hawk, E; Latchford, A; Liu, J; Lynch, PM; Malone, B; Morris, JS; Patterson, S; Phillips, R; Richmond, E; Rodriguez-Bigas, MA; Ross, WA; Sinicrope, FA; Slack, R; Wang, X	1
Cheng, NC; Corrigan, KA; Evageliou, NF; Gamble, LD; Gilmour, SK; Haber, M; Hayes, CS; Hogarty, MD; Laetsch, TW; Liu, K; Marshall, GM; Murray, J; Norris, MD; Pawel, B; Reese, M; Vu, A; Webber, H; Zhao, H; Ziegler, DS	1
Burke, CA; Chick, RC; Cindass, JL; Clifton, GT; Ensley, DC; Hale, DF; Hickerson, AT; Kemp Bohan, PM; Mankaney, G; Peoples, GE; Sohn, V; Vreeland, TJ	1

Reviews

2 review(s) available for celecoxib and eflornithine

Article	Year
Chemoprevention of familial adenomatous polyposis. Familial cancer, 2016, Volume: 15, Issue:3 Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Celecoxib; Chemotherapy, Adjuvant; Clinical Trials as Topic; Colectomy; Cyclooxygenase 2 Inhibitors; Drug Resistance, Neoplasm; Drug Synergism; Drug Therapy, Combination; Eflornithine; Evidence-Based Medicine; Humans; Prophylactic Surgical Procedures; Remission Induction; Sulindac	2016
Chemoprevention in familial adenomatous polyposis: past, present and future. Familial cancer, 2021, Volume: 20, Issue:1 Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Ascorbic Acid; Aspirin; Capsules; Celecoxib; Chemoprevention; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Eflornithine; Erlotinib Hydrochloride; Fatty Acids, Nonesterified; Genes, APC; Humans; Sirolimus; Sulindac; TOR Serine-Threonine Kinases; Vitamins	2021

Article

Year

Chemoprevention of familial adenomatous polyposis.

Familial cancer, 2016, Volume: 15, Issue:3

Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Celecoxib; Chemotherapy, Adjuvant; Clinical Trials as Topic; Colectomy; Cyclooxygenase 2 Inhibitors; Drug Resistance, Neoplasm; Drug Synergism; Drug Therapy, Combination; Eflornithine; Evidence-Based Medicine; Humans; Prophylactic Surgical Procedures; Remission Induction; Sulindac

2016

Chemoprevention in familial adenomatous polyposis: past, present and future.

Familial cancer, 2021, Volume: 20, Issue:1

Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Ascorbic Acid; Aspirin; Capsules; Celecoxib; Chemoprevention; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Eflornithine; Erlotinib Hydrochloride; Fatty Acids, Nonesterified; Genes, APC; Humans; Sirolimus; Sulindac; TOR Serine-Threonine Kinases; Vitamins

2021

Trials

1 trial(s) available for celecoxib and eflornithine

Article	Year
An international randomised trial of celecoxib versus celecoxib plus difluoromethylornithine in patients with familial adenomatous polyposis. Gut, 2016, Volume: 65, Issue:2 Topics: Adenomatous Polyps; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Cyclooxygenase 2 Inhibitors; Eflornithine; Female; Humans; Male; Middle Aged; Sigmoidoscopy; Tumor Burden; Young Adult	2016

Other Studies

8 other study(ies) available for celecoxib and eflornithine

Article	Year
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Celecoxib and difluoromethylornithine in combination have strong therapeutic activity against UV-induced skin tumors in mice. Carcinogenesis, 2003, Volume: 24, Issue:5 Topics: Animals; Antineoplastic Agents; Apoptosis; Celecoxib; Cell Division; Cyclooxygenase 2; Disease Progression; Drug Therapy, Combination; Eflornithine; Enzyme Inhibitors; Isoenzymes; Keratinocytes; Mice; Mice, Hairless; Neoplasms, Radiation-Induced; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Skin; Skin Neoplasms; Sulfonamides; Ultraviolet Rays	2003
Modulation by celecoxib and difluoromethylornithine of the methylation of DNA and the estrogen receptor-alpha gene in rat colon tumors. Carcinogenesis, 2004, Volume: 25, Issue:10 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azoxymethane; Biomarkers, Tumor; Carcinogens; Celecoxib; Colon; Colonic Neoplasms; CpG Islands; Diet; DNA Methylation; Eflornithine; Estrogen Receptor alpha; Male; Pyrazoles; Rats; Rats, Inbred F344; Receptors, Estrogen; RNA, Messenger; Sulfonamides	2004
Chemoprevention with special reference to inherited colorectal cancer. Familial cancer, 2008, Volume: 7, Issue:1 Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Ascorbic Acid; Celecoxib; Chemoprevention; Clinical Trials as Topic; Colorectal Neoplasms; Curcumin; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Eflornithine; Humans; Lactones; Pyrazoles; Sulfonamides; Sulfones; Sulindac; Vitamins	2008
Drugs to prevent colon cancer show promise, but hurdles remain for chemoprevention. Journal of the National Cancer Institute, 2008, Jun-04, Volume: 100, Issue:11 Topics: Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Cardiovascular System; Celecoxib; Colonic Neoplasms; Drug Administration Schedule; Eflornithine; Humans; National Cancer Institute (U.S.); Neoplasm Recurrence, Local; Pyrazoles; Randomized Controlled Trials as Topic; Sulfonamides; Sulindac; United States; United States Food and Drug Administration	2008
Combination chemoprevention of intestinal carcinogenesis in a murine model of familial adenomatous polyposis. Nutrition and cancer, 2008, Volume: 60 Suppl 1 Topics: Adenoma; Adenomatous Polyposis Coli; Animals; Biogenic Polyamines; Celecoxib; Chemoprevention; Eflornithine; Female; Genes, APC; Intestinal Neoplasms; Intestinal Polyps; Male; Mice; Mice, Inbred C57BL; Pyrazoles; Sulfonamides; Sulindac	2008
Polyamine Antagonist Therapies Inhibit Neuroblastoma Initiation and Progression. Clinical cancer research : an official journal of the American Association for Cancer Research, 2016, Sep-01, Volume: 22, Issue:17 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Disease Progression; Drug Evaluation, Preclinical; Drug Synergism; Eflornithine; Genes, myc; Homeostasis; Humans; Mice; Mice, Transgenic; Neuroblastoma; Oncogene Proteins; Polyamines; Treatment Outcome; Xenograft Model Antitumor Assays	2016