Compounds > celecoxib

celecoxib and dolastatin 15

celecoxib has been researched along with dolastatin 15 in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Piplani, H; Sanyal, SN; Vaish, V1
Piplani, H; Rana, C; Sanyal, SN; Vaish, V1
Piplani, H; Rana, C; Sanyal, SN; Vaiphei, K; Vaish, V1

Other Studies

3 other study(ies) available for celecoxib and dolastatin 15

ArticleYear
Dolastatin 15, a mollusk linear peptide, and Celecoxib, a selective cyclooxygenase-2 inhibitor, prevent preneoplastic colonic lesions and induce apoptosis through inhibition of the regulatory transcription factor NF-κB and an inflammatory protein, iNOS.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2012, Volume: 21, Issue:6

    Topics: Animals; Apoptosis; Blotting, Western; Celecoxib; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Depsipeptides; Fluorescent Antibody Technique; Intestinal Mucosa; Male; Molecular Docking Simulation; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Precancerous Conditions; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides

2012
Up-regulation of p53 and mitochondrial signaling pathway in apoptosis by a combination of COX-2 inhibitor, Celecoxib and Dolastatin 15, a marine mollusk linear peptide in experimental colon carcinogenesis.
    Molecular carcinogenesis, 2013, Volume: 52, Issue:11

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinogenesis; Caspases; Celecoxib; Colon; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Depsipeptides; Male; Membrane Potential, Mitochondrial; Mitochondria; Molecular Docking Simulation; Mollusca; Proto-Oncogene Proteins c-bcl-2; Pyrazoles; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfonamides; Tumor Suppressor Protein p53; Up-Regulation

2013
Dolastatin, along with Celecoxib, stimulates apoptosis by a mechanism involving oxidative stress, membrane potential change and PI3-K/AKT pathway down regulation.
    Biochimica et biophysica acta, 2013, Volume: 1830, Issue:11

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Binding Sites; Celecoxib; Cell Cycle Proteins; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Depsipeptides; Down-Regulation; Male; Membrane Potential, Mitochondrial; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyrazoles; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Sulfonamides

2013