celecoxib and ascorbic acid

celecoxib has been researched along with ascorbic acid in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (27.78)29.6817
2010's12 (66.67)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Bailly, F; Cotelle, P; Hénichart, JP; Mbemba, G; Mouscadet, JF; Pommery, J; Pommery, N; Queffélec, C1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ekins, S; Williams, AJ; Xu, JJ1
Dittrich, M; Greiner, C; Hieke, M; Reisen, F; Schneider, G; Schubert-Zsilavecz, M; Werz, O1
Barz, D; Dehm, F; Hanke, T; Kaiser, A; Kunze, J; Lämmerhofer, M; Liening, S; Maczewsky, J; Pillong, M; Popella, SD; Sautebin, L; Schneider, G; Schubert-Zsilavecz, M; Weinigel, C; Werz, O; Wurglics, M1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ameen, BAH; Dissanayake, AA; Nair, MG1
Elguero, J; Silva, AMS; Silva, VLM1
Asif, M; Husain, A; Iqbal, MA; Iram, F; Khan, SA1
Narang, RK; Pathania, S; Rawal, RK1
Banerjee, UC; Chakraborti, AK; Dave, K; Dubey, S; Garg, SK; Goyal, R; Kumar, R; Meena, VS; Purohit, P; Saha, N; Seth, K; Sharma, SS1
Astara, G; Deiana, L; Gramignano, G; Lusso, MR; Macciò, A; Madeddu, C; Mantovani, G; Massa, E; Serpe, R1
Caraccio, N; Dardano, A; Ferrannini, E; Ghiadoni, L; Monzani, F; Salvetti, A; Taddei, S; Versari, D; Virdis, A1
Lynch, PM1
Darzynkiewicz, Z; Dobrucki, J; Halicka, HD; Tanaka, T; Traganos, F; Zarebski, M; Zhao, H1
Ichi, I; Kamikawa, C; Kitamura, Y; Kobayashi, K; Koga, E; Kojo, S; Nakagawa, T; Nakazaki, C; Washino, Y1
Abdel-Moneim, LM; Daabees, TT; Mohamed, HF; Omar, AG; Senbel, AM1
Burke, CA; Chick, RC; Cindass, JL; Clifton, GT; Ensley, DC; Hale, DF; Hickerson, AT; Kemp Bohan, PM; Mankaney, G; Peoples, GE; Sohn, V; Vreeland, TJ1

Reviews

5 review(s) available for celecoxib and ascorbic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Current progress on antioxidants incorporating the pyrazole core.
    European journal of medicinal chemistry, 2018, Aug-05, Volume: 156

    Topics: Animals; Antioxidants; Drug Discovery; Humans; Oxidative Stress; Pyrazoles; Structure-Activity Relationship

2018
Insights into the chemistry and therapeutic potential of furanones: A versatile pharmacophore.
    European journal of medicinal chemistry, 2019, Jun-01, Volume: 171

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Antineoplastic Agents; Antiviral Agents; Humans; Molecular Structure

2019
Role of sulphur-heterocycles in medicinal chemistry: An update.
    European journal of medicinal chemistry, 2019, Oct-15, Volume: 180

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antihypertensive Agents; Antineoplastic Agents; Chemistry, Pharmaceutical; Heterocyclic Compounds; Humans; Hypoglycemic Agents; Sulfur

2019
Chemoprevention in familial adenomatous polyposis: past, present and future.
    Familial cancer, 2021, Volume: 20, Issue:1

    Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Ascorbic Acid; Aspirin; Capsules; Celecoxib; Chemoprevention; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Eflornithine; Erlotinib Hydrochloride; Fatty Acids, Nonesterified; Genes, APC; Humans; Sirolimus; Sulindac; TOR Serine-Threonine Kinases; Vitamins

2021

Trials

2 trial(s) available for celecoxib and ascorbic acid

ArticleYear
A phase II study with antioxidants, both in the diet and supplemented, pharmaconutritional support, progestagen, and anti-cyclooxygenase-2 showing efficacy and safety in patients with cancer-related anorexia/cachexia and oxidative stress.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2006, Volume: 15, Issue:5

    Topics: Adult; Aged; Anorexia; Ascorbic Acid; Cachexia; Carbocysteine; Celecoxib; Dietary Supplements; Docosahexaenoic Acids; Female; Humans; Linear Models; Male; Medroxyprogesterone; Middle Aged; Neoplasms; Nutritional Support; Oxidative Stress; Pyrazoles; Statistics, Nonparametric; Sulfonamides; Thioctic Acid; Treatment Outcome; Vitamin A; Vitamin E

2006
Low-grade systemic inflammation causes endothelial dysfunction in patients with Hashimoto's thyroiditis.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:12

    Topics: Acetylcholine; Adult; Algorithms; Ascorbic Acid; Celecoxib; Cyclooxygenase 2; Endothelium, Vascular; Female; Forearm; Hashimoto Disease; Humans; Indomethacin; Inflammation; Male; Membrane Proteins; Middle Aged; Nitric Oxide; Nitroprusside; Oxidative Stress; Pyrazoles; Regional Blood Flow; Sulfonamides; Vascular Diseases; Vasculitis; Vasodilation

2006

Other Studies

11 other study(ies) available for celecoxib and ascorbic acid

ArticleYear
Synthesis and biological activities of a series of 4,5-diaryl-3-hydroxy-2(5H)-furanones.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:6

    Topics: Base Sequence; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; DNA Primers; Furans; HIV Integrase Inhibitors; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Discovery and biological evaluation of a novel class of dual microsomal prostaglandin E2 synthase-1/5-lipoxygenase inhibitors based on 2-[(4,6-diphenethoxypyrimidin-2-yl)thio]hexanoic acid.
    Journal of medicinal chemistry, 2011, Jul-14, Volume: 54, Issue:13

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Benzene Derivatives; Binding Sites; Caproates; Cells, Cultured; Cyclooxygenase Inhibitors; Humans; Intramolecular Oxidoreductases; Ligands; Lipoxygenase Inhibitors; Microsomes; Models, Molecular; Prostaglandin-E Synthases; Pyrimidines; Recombinant Proteins; Structure-Activity Relationship

2011
Aminothiazole-featured pirinixic acid derivatives as dual 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 inhibitors with improved potency and efficiency in vivo.
    Journal of medicinal chemistry, 2013, Nov-27, Volume: 56, Issue:22

    Topics: Animals; Arachidonate 5-Lipoxygenase; Binding Sites; Drug Design; Humans; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Intramolecular Oxidoreductases; Lipoxygenase Inhibitors; Male; Mice; Microsomes; Models, Molecular; Peritonitis; Prostaglandin-E Synthases; Protein Conformation; Pyrimidines; Structure-Activity Relationship; Thiazoles; Zymosan

2013
Lipid Peroxidation and Cyclooxygenase Enzyme Inhibitory Compounds from Prangos haussknechtii.
    Journal of natural products, 2017, 09-22, Volume: 80, Issue:9

    Topics: Anti-Inflammatory Agents; Antioxidants; Coumarins; Cyclooxygenase Inhibitors; Lipid Peroxidation; Molecular Structure; Plant Extracts; Tetrazoles; Tetrazolium Salts; Thiazoles

2017
Cyclic enaminone as new chemotype for selective cyclooxygenase-2 inhibitory, anti-inflammatory, and analgesic activities.
    European journal of medicinal chemistry, 2019, Nov-15, Volume: 182

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carrageenan; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Edema; Heterocyclic Compounds; Humans; Male; Molecular Docking Simulation; Molecular Structure; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

2019
Chemoprevention with special reference to inherited colorectal cancer.
    Familial cancer, 2008, Volume: 7, Issue:1

    Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Ascorbic Acid; Celecoxib; Chemoprevention; Clinical Trials as Topic; Colorectal Neoplasms; Curcumin; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Eflornithine; Humans; Lactones; Pyrazoles; Sulfonamides; Sulfones; Sulindac; Vitamins

2008
Cytometric assessment of DNA damage by exogenous and endogenous oxidants reports aging-related processes.
    Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2007, Volume: 71, Issue:11

    Topics: Aging; Animals; Antioxidants; Ascorbic Acid; Ataxia Telangiectasia Mutated Proteins; Celecoxib; Cell Cycle Proteins; Cell Line; Dichloroacetic Acid; DNA Damage; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Histones; Humans; Hydrogen Peroxide; Oxidants; Oxidation-Reduction; Oxygen; Phosphorylation; Protein Serine-Threonine Kinases; Pyrazoles; Pyruvates; Sulfonamides; Tumor Suppressor Proteins

2007
Effect of celecoxib, a selective cyclooxygenase-2 inhibitor on carbon tetrachloride intoxication in rats.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:4

    Topics: Alanine Transaminase; Animals; Antioxidants; Ascorbic Acid; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Celecoxib; Ceramides; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2 Inhibitors; Liver; Male; Necrosis; Oxidative Stress; Pyrazoles; Rats; Rats, Wistar; Sulfonamides

2010
Evaluation of l-arginine on kidney function and vascular reactivity following ischemic injury in rats: protective effects and potential interactions.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:6

    Topics: Acetylcholine; Acute Kidney Injury; Animals; Antioxidants; Aorta; Arginine; Ascorbic Acid; Celecoxib; Cyclooxygenase 2; Drug Synergism; Kidney Function Tests; Nitric Oxide; Nitroprusside; Rats; Reactive Oxygen Species; Reperfusion Injury

2014