celecoxib and arachidonic acid

celecoxib has been researched along with arachidonic acid in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.70)18.2507
2000's23 (62.16)29.6817
2010's9 (24.32)24.3611
2020's4 (10.81)2.80

Authors

AuthorsStudies
Bhatti, R; Kaur, M; Sharma, S; Singh, A; Singh, P1
Bansal, R; Kumar, A; Saini, V; Singh, J1
Hamilton, LC; Mitchell, JA; Tomlinson, AM; Warner, TD1
Geis, GS; Hubbard, RC; Isakson, PC; Karim, A; Leese, PT; Yu, SS1
Levine, L3
Barrett, TD; Crofford, LJ; Driscoll, EM; Hennan, JK; Huang, J; Lucchesi, BR; Park, AM; Willens, DE1
Felix, E; Kempen, EC; Madden, T; Newman, RA; Yang, P1
Kessenich, CR1
Nervetti, A; Rioda, WT1
Capriotti, T1
Sharma, RA1
Adler, R; Eskra, J; Noveck, R; Rushing, M; Vargas, R; Walden, C; Wilner, KD1
Brum-Fernandes, AJ; Peters, RR; Ribeiro-do-Valle, RM; Siqueira-Junior, JM1
Dannenberg, AJ; Subbaramaiah, K1
Arroyo, V; Clària, J; Jiménez, W; López-Parra, M; Masferrer, JL; Párrizas, M; Planagumà, A; Rivera, F; Rodés, J; Titos, E1
Duffy, DM; Seachord, CL; VandeVoort, CA1
Chen, X; Fang, M; Li, N; Sood, S; Sun, Z; Wang, P; Wang, S; Yang, CS1
Bresee, SJ; Carroll, RC; Chavez, JJ; Cohen, E; Craft, RM; Snider, CC1
Hénichart, JP; Pommery, J; Pommery, N1
Capone, ML; D'Amelio, E; De Caterina, R; Grana, M; Patrignani, P; Patrono, C; Price, TS; Renda, G; Sacchetta, D; Santarelli, F; Sciulli, MG; Tacconelli, S; Zimarino, M; Zurro, M1
Klein, T; Pushkareva, MA; Shephard, P; Sud'ina, GF1
Caliari, MV; Duarte, ID; Francischi, JN; Maltos, KL; Pacheco, CM; Queiroz-Junior, CM1
Boyle, JO; Butala, GS; Dannenberg, AJ; Duffield-Lillico, AJ; Ghosh, A; Milne, GL; Morrow, JD; Newman, RA; Subbaramaiah, K; Zhou, XK1
Bauer, B; Hartz, AM; Miller, DS; Pekcec, A; Potschka, H; Unkrüer, B; Zibell, G1
Chen, L; Lv, X; Xiang, D; Xu, Z; Zhang, M; Zhang, X1
Aoyagi, T; Jia, Z; Liu, H; Wang, H; Wang, N; Yang, T1
Maldonado-Rojas, W; Olivero-Verbel, J1
Dong, L; Jurban, BJ; Sharma, NP; Smith, WL1
Aghazadeh-Habashi, A; Asghar, W; Jamali, F1
Alberts, DS; Hammock, BD; Lance, P; Martinez, JA; Roe, DJ; Schriewer, A; Thompson, PA; Wertheim, BC; Yang, J1
Anderson, AJ; Dong, L; Malkowski, MG1
Hibbeln, JR; Rapoport, SI1
Chew, WM; Chow, HS; Ellis, NA; Jacobs, ET; Lance, P; Martinez, JA; Saboda, K; Skiba, MB1
Desind, SZ; Iacona, JR; Lutz, CS; Mitrofanova, A; Yu, CY1
Anaya, FJ; Henry, K; Hong, J; Innis, RB; Kim, MJ; Lee, JH; Liow, JS; Manly, LS; Pike, VW; Santamaria, JAM; Shetty, HU; Shrestha, S; Telu, S; Zanotti-Fregonara, P; Zoghbi, SS1

Reviews

6 review(s) available for celecoxib and arachidonic acid

ArticleYear
Cyclo-oxygenase 2 inhibitors: an important new drug classification.
    Pain management nursing : official journal of the American Society of Pain Management Nurses, 2001, Volume: 2, Issue:1

    Topics: Acute Disease; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Celecoxib; Chronic Disease; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Forecasting; Humans; Inflammation; Isoenzymes; Lactones; Membrane Proteins; Pain; Patient Selection; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulfones

2001
[Specific inhibitors of cyclooxygenase-2 (COX-2): current knowledge and perspectives].
    Acta bio-medica de L'Ateneo parmense : organo della Societa di medicina e scienze naturali di Parma, 2001, Volume: 72, Issue:3-4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Isoenzymes; Lactones; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins G; Pyrazoles; Rheumatic Diseases; Sulfonamides; Sulfones

2001
The new NSAIDs: cox-2 inhibitors.
    Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses, 2000, Volume: 9, Issue:6

    Topics: Advertising; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Industry; Gastrointestinal Diseases; Humans; Isoenzymes; Lactones; Meloxicam; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Safety; Sulfonamides; Sulfones; Thiazines; Thiazoles

2000
Translational medicine: targetting cyclo-oxygenase isozymes to prevent cancer.
    QJM : monthly journal of the Association of Physicians, 2002, Volume: 95, Issue:5

    Topics: Arachidonic Acid; Aspirin; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Design; Humans; Isoenzymes; Lactones; Membrane Proteins; Neoplasms; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Randomized Controlled Trials as Topic; Sulfonamides; Sulfones

2002
Targeting cyclooxygenase-2 in human neoplasia: rationale and promise.
    Cancer cell, 2003, Volume: 4, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arachidonic Acid; Celecoxib; Cyclooxygenase 2; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Membrane Proteins; Models, Molecular; Neoplasms; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Receptors, Prostaglandin; Signal Transduction; Sulfonamides

2003
THERAPEUTIC TARGETING OF BRAIN ARACHIDONIC ACID CASCADE IN BIPOLAR DISORDER BY LOW DOSE ASPIRIN AND CELECOXIB.
    Prostaglandins, leukotrienes, and essential fatty acids, 2020, Volume: 159

    Topics: Arachidonic Acid; Aspirin; Bipolar Disorder; Brain; Celecoxib; Humans; Randomized Controlled Trials as Topic

2020

Trials

6 trial(s) available for celecoxib and arachidonic acid

ArticleYear
Effects of celecoxib, a novel cyclooxygenase-2 inhibitor, on platelet function in healthy adults: a randomized, controlled trial.
    Journal of clinical pharmacology, 2000, Volume: 40, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Bleeding Time; Blood Platelets; Celecoxib; Collagen; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Aggregation; Pyrazoles; Sulfonamides; Thromboxane B2

2000
Celecoxib does not affect the antiplatelet activity of aspirin in healthy volunteers.
    Journal of clinical pharmacology, 2002, Volume: 42, Issue:9

    Topics: Adenosine Diphosphate; Adolescent; Adult; Arachidonic Acid; Aspirin; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Interactions; Female; Humans; Isoenzymes; Male; Membrane Proteins; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Thromboxane B2

2002
Celecoxib, ibuprofen, and the antiplatelet effect of aspirin in patients with osteoarthritis and ischemic heart disease.
    Clinical pharmacology and therapeutics, 2006, Volume: 80, Issue:3

    Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Celecoxib; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Middle Aged; Myocardial Ischemia; Osteoarthritis; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Pyrazoles; Sulfonamides; Thromboxane B2; Treatment Outcome

2006
Levels of prostaglandin E metabolite and leukotriene E(4) are increased in the urine of smokers: evidence that celecoxib shunts arachidonic acid into the 5-lipoxygenase pathway.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:4

    Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Female; Humans; Leukotriene E4; Male; Middle Aged; Pneumonia; Prostaglandins E; Pyrazoles; Signal Transduction; Smoking; Sulfonamides

2009
Celecoxib use and circulating oxylipins in a colon polyp prevention trial.
    PloS one, 2018, Volume: 13, Issue:4

    Topics: Adenomatous Polyps; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Blood Pressure; Celecoxib; Colon; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Female; Humans; Male; Middle Aged; Oxylipins; Placebo Effect; Polyps; Selenium

2018
A Protective Role for Arachidonic Acid Metabolites against Advanced Colorectal Adenoma in a Phase III Trial of Selenium.
    Nutrients, 2021, Oct-29, Volume: 13, Issue:11

    Topics: Adenoma; Aged; Arachidonic Acid; Celecoxib; Colorectal Neoplasms; Dietary Supplements; Disease Progression; Female; Follow-Up Studies; Humans; Male; Middle Aged; Oxylipins; Selenium; Treatment Outcome

2021

Other Studies

25 other study(ies) available for celecoxib and arachidonic acid

ArticleYear
Rational design, synthesis and evaluation of chromone-indole and chromone-pyrazole based conjugates: identification of a lead for anti-inflammatory drug.
    European journal of medicinal chemistry, 2014, Apr-22, Volume: 77

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Chromones; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Indoles; Mice; Models, Molecular; Molecular Structure; Pain; Pain Measurement; Pyrazoles; Structure-Activity Relationship

2014
Synthesis, molecular docking and biological evaluation of some newer 2-substituted-4-(benzo[d][1,3]dioxol-5-yl)-6-phenylpyridazin-3(2H)-ones as potential anti-inflammatory and analgesic agents.
    Bioorganic chemistry, 2017, Volume: 71

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Edema; Humans; Male; Mice; Molecular Docking Simulation; Pyridazines; Rats, Wistar; Stomach Ulcer

2017
Synergy between cyclo-oxygenase-2 induction and arachidonic acid supply in vivo: consequences for nonsteroidal antiinflammatory drug efficacy.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1999, Volume: 13, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Antagonism; Drug Synergism; Enzyme Induction; Humans; Inflammation; Isoenzymes; Lipopolysaccharides; Male; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; Sulfonamides

1999
Stimulated release of arachidonic acid from rat liver cells by celecoxib and indomethacin.
    Prostaglandins, leukotrienes, and essential fatty acids, 2001, Volume: 65, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Celecoxib; Cell Line; Cycloheximide; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dactinomycin; Dexamethasone; Drug Interactions; Glucocorticoids; Indomethacin; Isoenzymes; Liver; Prostaglandin-Endoperoxide Synthases; Protein Synthesis Inhibitors; Pyrazoles; Rats; Sulfonamides

2001
Effects of selective cyclooxygenase-2 inhibition on vascular responses and thrombosis in canine coronary arteries.
    Circulation, 2001, Aug-14, Volume: 104, Issue:7

    Topics: Acetylcholine; Animals; Arachidonic Acid; Aspirin; Benzofurans; Blood Flow Velocity; Celecoxib; Coronary Circulation; Coronary Thrombosis; Coronary Vessels; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Epoprostenol; Isoenzymes; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Thromboxane-A Synthase; Time Factors; Vasodilation; Vasomotor System

2001
Simultaneous quantification of arachidonic acid metabolites in cultured tumor cells using high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.
    Analytical biochemistry, 2001, Oct-15, Volume: 297, Issue:2

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acid; Celecoxib; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Isoenzymes; Leukemia; Lipoxygenase; Lung Neoplasms; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Spectrometry, Mass, Electrospray Ionization; Sulfonamides; Tumor Cells, Cultured

2001
Stimulated release of arachidonic acid by agonists of the peroxisome proliferator-activated receptor and retinoic acid receptors.
    Prostaglandins, leukotrienes, and essential fatty acids, 2001, Volume: 65, Issue:4

    Topics: Alitretinoin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Celecoxib; Cell Line; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Drug Synergism; Indomethacin; Kinetics; Liver; Prostaglandin D2; Prostaglandins A; Pyrazoles; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Sulfonamides; Thiazoles; Thiazolidinediones; Transcription Factors; Tretinoin

2001
Does the release of arachidonic acid from cells play a role in cancer chemoprevention?
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Arachidonic Acid; Catechin; Celecoxib; Cholecalciferol; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Epoprostenol; Humans; Indomethacin; Isoenzymes; Kidney; Liver; Membrane Proteins; Neoplasms; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Retinoids; Sulfonamides; Tetradecanoylphorbol Acetate

2003
Effects of valeryl salicylate, a COX-1 inhibitor, on models of acute inflammation in mice.
    Pharmacological research, 2003, Volume: 48, Issue:5

    Topics: Acute Disease; Animals; Arachidonic Acid; Carrageenan; Celecoxib; Croton Oil; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ear, External; Edema; Foot; Indomethacin; Inflammation; Irritants; Isoenzymes; Male; Membrane Proteins; Mice; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Salicylates; Sulfonamides

2003
The selective cyclooxygenase-2 inhibitor celecoxib modulates the formation of vasoconstrictor eicosanoids and activates PPARgamma. Influence of albumin.
    Journal of hepatology, 2005, Volume: 42, Issue:1

    Topics: Actins; Albumins; Animals; Arachidonic Acid; Celecoxib; Cyclooxygenase Inhibitors; Eicosanoids; Male; PPAR gamma; Prostaglandin D2; Pyrazoles; Rats; Rats, Sprague-Dawley; Renin; Sulfonamides

2005
Adipose differentiation-related protein: a gonadotropin- and prostaglandin-regulated protein in primate periovulatory follicles.
    Biology of reproduction, 2005, Volume: 72, Issue:6

    Topics: Animals; Arachidonic Acid; Celecoxib; Cells, Cultured; Chorionic Gonadotropin; Cyclooxygenase Inhibitors; Dinoprostone; Female; Gene Expression Regulation; Gonadotropins; Granulosa Cells; Macaca mulatta; Membrane Proteins; Ovarian Follicle; Ovulation; Perilipin-2; Primates; Prostaglandins; Pyrazoles; RNA, Messenger; Sulfonamides

2005
Overexpression of 5-lipoxygenase and cyclooxygenase 2 in hamster and human oral cancer and chemopreventive effects of zileuton and celecoxib.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Mar-01, Volume: 11, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Carcinogens; Carcinoma, Squamous Cell; Celecoxib; Cell Transformation, Neoplastic; Chemoprevention; Cricetinae; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Humans; Hydroxyurea; Immunohistochemistry; In Situ Hybridization; Lipoxygenase Inhibitors; Male; Membrane Proteins; Mesocricetus; Mouth Neoplasms; Neoplasms, Experimental; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Up-Regulation

2005
A Thrombelastograph whole blood assay for clinical monitoring of NSAID-insensitive transcellular platelet activation by arachidonic acid.
    The Journal of laboratory and clinical medicine, 2005, Volume: 146, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Celecoxib; Dose-Response Relationship, Drug; Humans; Ibuprofen; Platelet Activation; Platelet Aggregation; Pyrazoles; Sulfonamides; Thrombelastography

2005
Modification of eicosanoid profile in human blood treated by dual COX/LOX inhibitors.
    Prostaglandins, leukotrienes, and essential fatty acids, 2005, Volume: 73, Issue:6

    Topics: Arachidonic Acid; Calcimycin; Celecoxib; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Eicosanoids; Humans; Hydroxyurea; Indomethacin; Inhibitory Concentration 50; Lipopolysaccharides; Lipoxygenase Inhibitors; Pyrazoles; Sulfonamides

2005
Cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) selectivity of COX inhibitors.
    Prostaglandins, leukotrienes, and essential fatty acids, 2008, Volume: 78, Issue:2

    Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Blood; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Female; Humans; Indoles; Isoenzymes; Lipoxygenase Inhibitors; Molecular Structure; Neutrophils; Pyrazoles; Pyrroles; Random Allocation; Sulfonamides

2008
Role of systemic and local administration of selective inhibitors of cyclo-oxygenase 1 and 2 in an experimental model of periodontal disease in rats.
    Journal of periodontal research, 2009, Volume: 44, Issue:2

    Topics: Alveolar Bone Loss; Animals; Arachidonic Acid; Celecoxib; Cyclooxygenase Inhibitors; Disease Models, Animal; Indomethacin; Male; Periodontal Attachment Loss; Periodontal Ligament; Periodontitis; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides

2009
Prevention of seizure-induced up-regulation of endothelial P-glycoprotein by COX-2 inhibition.
    Neuropharmacology, 2009, Volume: 56, Issue:5

    Topics: Animals; Arachidonic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Capillaries; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Glutamic Acid; In Vitro Techniques; Male; Nitrobenzenes; Protein Transport; Pyrazoles; Rats; Rats, Sprague-Dawley; Status Epilepticus; Sulfonamides; Up-Regulation

2009
The inhibitory effect of celecoxib on mouse hepatoma H22 cell line on the arachidonic acid metabolic pathway.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2010, Volume: 88, Issue:4

    Topics: Animals; Arachidonic Acid; Biomarkers, Pharmacological; Biomarkers, Tumor; Carcinoma, Hepatocellular; Celecoxib; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Drug Evaluation, Preclinical; Liver Neoplasms; Metabolic Networks and Pathways; Mice; Phospholipases A2; Pyrazoles; Sulfonamides

2010
Amelioration of cisplatin nephrotoxicity by genetic or pharmacologic blockade of prostaglandin synthesis.
    Kidney international, 2011, Volume: 79, Issue:1

    Topics: Acute Kidney Injury; Animals; Arachidonic Acid; Blood Urea Nitrogen; Celecoxib; Cisplatin; Creatinine; Cyclooxygenase 2 Inhibitors; Dinoprostone; Gene Expression; Interleukin-1beta; Intramolecular Oxidoreductases; Male; Mice; Mice, Knockout; Prostaglandin-E Synthases; Pyrazoles; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Sulfonamides; Tumor Necrosis Factor-alpha

2011
Potential interaction of natural dietary bioactive compounds with COX-2.
    Journal of molecular graphics & modelling, 2011, Volume: 30

    Topics: Amino Acid Motifs; Animals; Arachidonic Acid; Catalytic Domain; Celecoxib; Computer Simulation; Curcumin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Fish Oils; Food; Hydrophobic and Hydrophilic Interactions; Lutein; Mice; Models, Molecular; Plant Extracts; Protein Binding; Pyrazoles; Sulfonamides; Thermodynamics

2011
Pre-existent asymmetry in the human cyclooxygenase-2 sequence homodimer.
    The Journal of biological chemistry, 2013, Oct-04, Volume: 288, Issue:40

    Topics: Acetylation; Amino Acid Sequence; Amino Acid Substitution; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Flurbiprofen; Guanidine; Heme; Humans; Indomethacin; Kinetics; Models, Biological; Mutant Proteins; Mutation; Naproxen; Oxygen; Palmitic Acid; Peroxidase; Protein Multimerization; Pyrazoles; Substrate Specificity; Sulfonamides

2013
Drug-Disease Interaction: Effect of Inflammation and Nonsteroidal Anti-Inflammatory Drugs on Cytochrome P450 Metabolites of Arachidonic Acid.
    Journal of pharmaceutical sciences, 2018, Volume: 107, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arthritis, Experimental; Celecoxib; Cytochrome P-450 Enzyme System; Heart; Hydroxyeicosatetraenoic Acids; Inflammation; Kidney; Lactones; Male; Meloxicam; Rats; Rats, Sprague-Dawley; Sulfones; Thiazines; Thiazoles

2018
Arg-513 and Leu-531 Are Key Residues Governing Time-Dependent Inhibition of Cyclooxygenase-2 by Aspirin and Celebrex.
    Biochemistry, 2019, 09-24, Volume: 58, Issue:38

    Topics: Animals; Arachidonic Acid; Arginine; Aspirin; Celecoxib; Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Enzyme Assays; Histidine; Hydroxyeicosatetraenoic Acids; Leucine; Mutagenesis, Site-Directed; Recombinant Proteins; Sf9 Cells; Stereoisomerism; Substrate Specificity; Time Factors

2019
PACER lncRNA regulates COX-2 expression in lung cancer cells.
    Oncotarget, 2022, Volume: 13

    Topics: Arachidonic Acid; Celecoxib; Cyclooxygenase 2; Cytokines; Dinoprostone; Humans; Inflammation; Lung; Lung Neoplasms; NF-kappa B; RNA, Long Noncoding; RNA, Small Interfering; Transcription Factor AP-1

2022
Whole-Body PET Imaging in Humans Shows That
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2023, Volume: 64, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Ketoprofen; Positron-Emission Tomography

2023