celecoxib has been researched along with 2,5-dimethylcelecoxib in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (38.89) | 29.6817 |
| 2010's | 7 (38.89) | 24.3611 |
| 2020's | 4 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Assefnia, S; Brown, ML; Byers, SW; Dakshanamurthy, S; Issa, NT; Madhavan, S; Peters, OJ; Seshasayee, A; Uren, A | 1 |
| Chen, TC; Hofman, FM; Kardosh, A; Petasis, NA; Schönthal, AH; Uddin, J; Wang, W | 1 |
| Dent, P; Grant, S; Yacoub, A | 1 |
| Chen, CS; Chen, TC; Hofman, FM; Kardosh, A; Liu, YT; Petasis, NA; Pyrko, P; Schönthal, AH; Soriano, N; Uddin, J | 1 |
| Chen, TC; Chow, RH; Farley, RA; Kardosh, A; Liu, YT; Louie, SG; Mircheff, AK; Petasis, NA; Pyrko, P; Schönthal, AH; Soriano, N; Uddin, J; Xiong, W | 1 |
| Chen, S; Khuri, FR; Liu, X; Schönthal, AH; Sun, SY; Yue, P | 1 |
| Chen, TC; Hofman, FM; Louie, SG; Petasis, NA; Schönthal, AH | 1 |
| Chen, TC; Golden, EB; Hofman, FM; Kardosh, A; Louie, SG; Petasis, NA; Pyrko, P; Schönthal, AH; Uddin, J | 1 |
| Fan, X; Igawa, K; Morimoto, S; Sasaguri, T; Takahashi-Yanaga, F; Tomooka, K; Zhan, DY | 1 |
| An, HL; Du, XN; Fu, Y; Gao, HX; Gao, ZB; Li, JW; Qi, JL; Wan, YM; Zhan, Y; Zhang, HL; Zhang, X | 1 |
| Agarwal, P; Chen, TC; Cho, H; Gaffney, KJ; Golden, EB; Hofman, FM; Louie, SG; Petasis, NA; Schönthal, AH; Sharma, N; Thomas, S | 1 |
| Cerella, C; Chateauvieux, S; Dicato, M; Diederich, M; Kim, JG; Kim, KW; Legrand, N; Mack, F; Muller, F; Rhim, J; Sobolewski, C; Yoon, AY | 1 |
| Li, Y; Lin, N; Wang, L; Wang, M; Yan, Y; Zeng, J; Zhang, B; Zhang, D | 1 |
| Arioka, M; Egashira, I; Igawa, K; Kitazono, T; Nakabeppu, Y; Nakatsu, Y; Nishida, R; Sasaguri, T; Takahashi-Yanaga, F; Tomooka, K; Tsuzuki, T | 1 |
| Kleszcz, R; Krajka-Kuźniak, V; Kruhlenia, N; Majchrzak-Celińska, A; Misiorek, JO; Przybyl, L; Rolle, K | 1 |
| Legrand, N; Sobolewski, C | 1 |
| Chen, Z; Lin, H; Pan, B; Qiu, J; Tang, N; Tu, H; Wang, Z; Wu, X; Yao, Y; Yu, L; Zhang, X | 1 |
| Dai, W; Gao, J; Huang, Z; Tang, C; Tong, H; Yang, W; Zhang, L; Zhao, C | 1 |
2 review(s) available for celecoxib and 2,5-dimethylcelecoxib
| Article | Year |
|---|---|
Celecoxib analogs that lack COX-2 inhibitory function: preclinical development of novel anticancer drugs.
Topics: Animals; Antineoplastic Agents; Celecoxib; Cyclooxygenase 2; Drug Evaluation, Preclinical; Humans; Neoplasms; Neovascularization, Pathologic; Pyrazoles; Sulfonamides | 2008 |
Celecoxib Analogues for Cancer Treatment: An Update on OSU-03012 and 2,5-Dimethyl-Celecoxib.
Topics: Animals; Antineoplastic Agents; Celecoxib; Cell Cycle; Cyclooxygenase 2 Inhibitors; Humans; Neoplasms; Pyrazoles; Sulfonamides | 2021 |
16 other study(ies) available for celecoxib and 2,5-dimethylcelecoxib
| Article | Year |
|---|---|
Predicting new indications for approved drugs using a proteochemometric method.
Topics: Animals; Antineoplastic Agents; Antirheumatic Agents; Cadherins; Celecoxib; Cell Line, Tumor; Crystallography, X-Ray; Databases, Factual; Drug Discovery; Drug Repositioning; Drugs, Investigational; Human Umbilical Vein Endothelial Cells; Humans; Mebendazole; Mice; Models, Molecular; Neovascularization, Pathologic; Pharmaceutical Preparations; Protein Binding; Protein Conformation; Proteins; Pyrazoles; Sulfonamides; United States; United States Food and Drug Administration; Vascular Endothelial Growth Factor Receptor-2 | 2012 |
Dimethyl-celecoxib (DMC), a derivative of celecoxib that lacks cyclooxygenase-2-inhibitory function, potently mimics the anti-tumor effects of celecoxib on Burkitt's lymphoma in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Burkitt Lymphoma; Celecoxib; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Immunohistochemistry; In Vitro Techniques; Male; Mice; Mice, Nude; Molecular Structure; Neoplasm Transplantation; Pyrazoles; Sulfonamides; Transplantation, Heterologous; Xenograft Model Antitumor Assays | 2005 |
DMC: novel celecoxib derivatives to rap cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Celecoxib; Cell Cycle Proteins; Cell Proliferation; Cyclin A; Cyclin B; Cyclin-Dependent Kinase Inhibitor p27; Cyclooxygenase Inhibitors; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Transplantation; Phosphorylation; Pyrazoles; Sulfonamides; Transplantation, Heterologous; Xenograft Model Antitumor Assays | 2005 |
Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Celecoxib; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation; HCT116 Cells; Humans; Inhibitor of Apoptosis Proteins; Irinotecan; Male; Mice; Mice, Nude; Microtubule-Associated Proteins; Neoplasm Proteins; Neuroblastoma; Promoter Regions, Genetic; Pyrazoles; Sulfonamides; Survivin; Transcription, Genetic; Transfection; Xenograft Model Antitumor Assays | 2006 |
Calcium-activated endoplasmic reticulum stress as a major component of tumor cell death induced by 2,5-dimethyl-celecoxib, a non-coxib analogue of celecoxib.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Caspases, Initiator; Celecoxib; Cell Death; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2 Inhibitors; Cytoplasm; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Humans; Mice; Mice, Nude; Molecular Chaperones; Protein Biosynthesis; Pyrazoles; Sulfonamides; Thapsigargin; Transcription Factor CHOP | 2007 |
CCAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction and ubiquitin/proteasome-mediated cellular FLICE-inhibitory protein down-regulation contribute to enhancement of tumor necrosis factor-related apoptosis-inducing ligand
Topics: Antineoplastic Agents; Apoptosis Regulatory Proteins; Carcinoma, Non-Small-Cell Lung; CASP8 and FADD-Like Apoptosis Regulating Protein; CCAAT-Enhancer-Binding Proteins; Celecoxib; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase Inhibitors; Down-Regulation; Humans; Lung Neoplasms; MAP Kinase Kinase 4; Neoplasms; Proteasome Endopeptidase Complex; Pyrazoles; Receptors, TNF-Related Apoptosis-Inducing Ligand; Sulfonamides; TNF-Related Apoptosis-Inducing Ligand; Transcription Factor CHOP; Ubiquitin | 2007 |
Aggravated endoplasmic reticulum stress as a basis for enhanced glioblastoma cell killing by bortezomib in combination with celecoxib or its non-coxib analogue, 2,5-dimethyl-celecoxib.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Celecoxib; Cell Death; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; Drug Synergism; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Glioblastoma; Heat-Shock Proteins; Humans; Male; Mice; Mice, Nude; Molecular Chaperones; Pyrazines; Pyrazoles; Sulfonamides; Transfection; Xenograft Model Antitumor Assays | 2008 |
Celecoxib and 2,5-dimethyl-celecoxib prevent cardiac remodeling inhibiting Akt-mediated signal transduction in an inherited dilated cardiomyopathy mouse model.
Topics: Animals; Cardiomyopathy, Dilated; Celecoxib; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Knock-In Techniques; Mice; Proto-Oncogene Proteins c-akt; Pyrazoles; Signal Transduction; Sulfonamides; Ventricular Remodeling | 2011 |
Characteristics and molecular basis of celecoxib modulation on K(v)7 potassium channels.
Topics: Animals; Carbamates; Celecoxib; Cells, Cultured; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; HEK293 Cells; Humans; KCNQ Potassium Channels; Neurons; Phenylenediamines; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Superior Cervical Ganglion; Transfection | 2011 |
Preferential killing of triple-negative breast cancer cells in vitro and in vivo when pharmacological aggravators of endoplasmic reticulum stress are combined with autophagy inhibitors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Breast Neoplasms; Celecoxib; Cell Line, Tumor; Chloroquine; Endoplasmic Reticulum Stress; Female; Humans; MCF-7 Cells; Mice; Mice, Nude; Nelfinavir; Pyrazoles; Sulfonamides; Xenograft Model Antitumor Assays | 2012 |
2,5-Dimethyl-celecoxib inhibits cell cycle progression and induces apoptosis in human leukemia cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Calcium; Celecoxib; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2 Inhibitors; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Humans; Leukemia; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-myc; Pyrazoles; Sulfonamides; Zebrafish | 2015 |
Dimethyl celecoxib sensitizes gastric cancer cells to ABT-737 via AIF nuclear translocation.
Topics: Apoptosis; Apoptosis Inducing Factor; Biphenyl Compounds; Celecoxib; Cell Line, Tumor; Cell Lineage; Cell Nucleus; Drug Synergism; Endoplasmic Reticulum Stress; Humans; Membrane Potential, Mitochondrial; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Nitrophenols; Piperazines; Protein Transport; Pyrazoles; Stomach Neoplasms; Sulfonamides | 2016 |
Celecoxib and 2,5-dimethylcelecoxib inhibit intestinal cancer growth by suppressing the Wnt/β-catenin signaling pathway.
Topics: Animals; beta Catenin; Blood Cell Count; Body Weight; Celecoxib; Cell Line, Tumor; DNA Glycosylases; Female; Humans; Intestinal Neoplasms; Male; Mice; Oxidative Stress; Proteolysis; Pyrazoles; Sulfonamides; TCF Transcription Factors; Transcription Factor 7-Like 2 Protein; Transcription, Genetic; Wnt Proteins; Wnt Signaling Pathway | 2017 |
COXIBs and 2,5-dimethylcelecoxib counteract the hyperactivated Wnt/β-catenin pathway and COX-2/PGE2/EP4 signaling in glioblastoma cells.
Topics: Aged; Antineoplastic Agents, Alkylating; Apoptosis; beta Catenin; Brain Neoplasms; Celecoxib; Cell Cycle; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; DNA Modification Methylases; DNA Repair Enzymes; Dose-Response Relationship, Drug; Etoricoxib; Female; Glioblastoma; Humans; Isoxazoles; Lactones; Male; Methylation; Middle Aged; Neoplasm Proteins; Pyrazoles; Receptors, Prostaglandin E, EP4 Subtype; Sulfonamides; Sulfones; Temozolomide; Tumor Suppressor Proteins; Wnt Signaling Pathway | 2021 |
2,5-dimethylcelecoxib alleviated NK and T-cell exhaustion in hepatocellular carcinoma via the gastrointestinal microbiota-AMPK-mTOR axis.
Topics: AMP-Activated Protein Kinases; Animals; Carcinoma, Hepatocellular; Celecoxib; Dinoprostone; Gastrointestinal Microbiome; Liver Neoplasms; Mice; T-Cell Exhaustion; Tumor Microenvironment | 2023 |
Disruption of cholangiocyte-B cell crosstalk by blocking the CXCL12-CXCR4 axis alleviates liver fibrosis.
Topics: Animals; Celecoxib; Cell Proliferation; Chemokine CXCL12; Cyclooxygenase 2; Epithelial Cells; Humans; Liver Cirrhosis; Mice; Receptors, CXCR4; Signal Transduction; Transforming Growth Factor beta | 2023 |