celecoxib has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Demetris, AJ; Han, C; Leng, J; Wu, T | 1 |
| Cheang, M; Chen, CS; Dunn, SE; Emerman, J; Gilks, CB; Huntsman, D; Kucab, JE; Lee, C; Pollak, M; Yorida, E; Zhu, J | 1 |
| Beales, IL; Ogunwobi, O | 1 |
| Ahn, DW; Cho, SJ; Jung, HC; Kim, CH; Kim, JS; Kim, N; Lee, KS; Lee, MK; Park, JH; Song, IS | 1 |
| El-Hefnawy, T; Kilic, A; Landreneau, RJ; Luketich, JD; Schuchert, MJ | 1 |
| Chang, JK; Chou, CH; Ho, ML; Li, CJ; Wang, GJ | 1 |
| Xia, S; Yu, S; Zhang, M; Zhao, Y | 1 |
| Bai, J; Chang, W; Du, H; Long, Y; Sun, Z; Tao, K; Tian, S; Wang, H; Zhang, Q; Zhu, G | 1 |
| Cai, N; Liu, NN; Sun, YZ | 1 |
10 other study(ies) available for celecoxib and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
The cyclooxygenase-2 inhibitor celecoxib blocks phosphorylation of Akt and induces apoptosis in human cholangiocarcinoma cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Caspase 9; Caspases; Celecoxib; Cell Death; Cell Line, Tumor; Cell Survival; Cholangiocarcinoma; Chromones; Cyclooxygenase 2; Cytochromes c; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Immunoassay; Immunohistochemistry; Isoenzymes; Membrane Proteins; Microscopy, Fluorescence; Morpholines; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyrazoles; Sulfonamides; Threonine; Time Factors | 2004 |
Celecoxib analogues disrupt Akt signaling, which is commonly activated in primary breast tumours.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Breast Neoplasms; Celecoxib; Cell Line, Tumor; Cell Survival; Chromones; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Humans; Morpholines; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrazoles; Signal Transduction; Sulfonamides | 2005 |
Glycine-extended gastrin inhibits apoptosis in colon cancer cells via separate activation of Akt and JNK pathways.
Topics: Anthracenes; Apoptosis; Celecoxib; Cell Line, Tumor; Cell Survival; Chromones; Colonic Neoplasms; Gastrins; Humans; Janus Kinase 2; JNK Mitogen-Activated Protein Kinases; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrazoles; Signal Transduction; STAT3 Transcription Factor; Sulfonamides; Transcription Factor AP-1; Tyrosine; Tyrphostins | 2006 |
Anti-gastric cancer effects of celecoxib, a selective COX-2 inhibitor, through inhibition of Akt signaling.
Topics: Antineoplastic Agents; Blotting, Western; Caspase 9; Celecoxib; Cell Death; Cell Line, Tumor; Chromones; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Forkhead Transcription Factors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Indomethacin; Morpholines; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazoles; Signal Transduction; Stomach Neoplasms; Sulfonamides; Time Factors | 2009 |
Efficacy of signal pathway inhibitors alone and in combination with Cisplatin varies between human non-small cell lung cancer lines.
Topics: Carcinoma, Non-Small-Cell Lung; Celecoxib; Cell Line, Tumor; Chromones; Cisplatin; Cyclooxygenase Inhibitors; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Gossypol; Humans; Lung Neoplasms; Morpholines; Pyrazoles; Signal Transduction; Sulfonamides | 2009 |
The PI3K/Akt/FOXO3a/p27Kip1 signaling contributes to anti-inflammatory drug-suppressed proliferation of human osteoblasts.
Topics: Anti-Inflammatory Agents; Celecoxib; Cell Proliferation; Cells, Cultured; Chromones; Cyclin-Dependent Kinase Inhibitor p27; Dextroamphetamine; Epidermal Growth Factor; Female; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Indomethacin; Male; Morpholines; Osteoblasts; Phosphatidylinositol 3-Kinases; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Pyrazoles; Sulfonamides | 2010 |
Activated PI3K/Akt/COX-2 pathway induces resistance to radiation in human cervical cancer HeLa cells.
Topics: bcl-Associated Death Protein; Celecoxib; Cell Proliferation; Cell Survival; Chromones; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Enzyme Inhibitors; Gene Expression; HeLa Cells; Humans; Inhibitory Concentration 50; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrazoles; Radiation Tolerance; Radiation-Sensitizing Agents; Signal Transduction; Sulfonamides; X-Rays | 2010 |
The interplay between GRP78 expression and Akt activation in human colon cancer cells under celecoxib treatment.
Topics: Antineoplastic Agents; Apoptosis; Celecoxib; Cell Line, Tumor; Chromones; Colonic Neoplasms; Endoplasmic Reticulum Chaperone BiP; Gene Silencing; Heat-Shock Proteins; Humans; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazoles; Sulfonamides; Transcription Factor CHOP; Unfolded Protein Response | 2015 |
Celecoxib Down-Regulates the Hypoxia-Induced Expression of HIF-1α and VEGF Through the PI3K/AKT Pathway in Retinal Pigment Epithelial Cells.
Topics: Celecoxib; Cell Hypoxia; Cell Line; Cell Proliferation; Chromones; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Down-Regulation; Epithelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; RNA, Messenger; Signal Transduction; Vascular Endothelial Growth Factor A | 2017 |