celastrol methyl ester has been researched along with quinacrine in 2 studies
| Studies (celastrol methyl ester) | Trials (celastrol methyl ester) | Recent Studies (post-2010) (celastrol methyl ester) | Studies (quinacrine) | Trials (quinacrine) | Recent Studies (post-2010) (quinacrine) |
|---|---|---|---|---|---|
| 39 | 0 | 27 | 4,051 | 65 | 289 |
| Protein | Taxonomy | celastrol methyl ester (IC50) | quinacrine (IC50) |
|---|---|---|---|
| cystic fibrosis transmembrane conductance regulator | Homo sapiens (human) | 19.88 | |
| Major prion protein | Mus musculus (house mouse) | 0.0951 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 2.896 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.964 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 1.983 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 4.5 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 4.5 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 4.5 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 4.5 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 3.736 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 2.28 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 4.5 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 1.489 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 1.825 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 3.857 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 1.255 | |
| Acetylcholinesterase | Homo sapiens (human) | 2.667 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 2.896 | |
| Histamine H2 receptor | Homo sapiens (human) | 3.535 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 2.065 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 2.663 | |
| D(3) dopamine receptor | Homo sapiens (human) | 1.318 | |
| Aldehyde oxidase 1 | Oryctolagus cuniculus (rabbit) | 10 | |
| Cholinesterase | Equus caballus (horse) | 4.5 | |
| Aldehyde oxidase | Homo sapiens (human) | 3.3 | |
| Cyclic GMP-AMP synthase | Homo sapiens (human) | 7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adrián, F; Anderson, P; Brinker, A; Caldwell, JS; Chatterjee, A; Gray, NS; Henson, K; Janes, J; Kato, N; Kuhen, K; Matzen, JT; McNamara, C; Nagle, A; Nam, TG; Plouffe, D; Schultz, PG; Trager, R; Winzeler, EA; Yan, SF; Zhou, Y | 1 |
| Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y | 1 |
2 other study(ies) available for celastrol methyl ester and quinacrine
| Article | Year |
|---|---|
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
Topics: Animals; Antimalarials; Cluster Analysis; Computational Biology; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Malaria; Models, Molecular; Parasites; Plasmodium falciparum; Reproducibility of Results; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 2008 |
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Humans; Imidazoles; Liver; Malaria; Mice; Mice, Inbred BALB C; Molecular Structure; Piperazines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Polymorphism, Single Nucleotide; Protozoan Proteins; Random Allocation; Small Molecule Libraries; Sporozoites | 2011 |