Page last updated: 2024-09-03

celastrol and triptohypol C

celastrol has been researched along with triptohypol C in 7 studies

Compound Research Comparison

Studies
(celastrol)
Trials
(celastrol)
Recent Studies (post-2010)
(celastrol)
Studies
(triptohypol C)
Trials
(triptohypol C)
Recent Studies (post-2010) (triptohypol C)
8851741908

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (85.71)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Chang, JS; Kim, YM; Lee, JY; Lee, WS; Park, KH; Park, SJ; Rho, MC; Ryu, YB; Seo, WD1
Cascante, M; Cortés, R; Figueiredo, SAC; Salvador, JAR2
Cowley, MA; De Angelis, M; Dodd, GT; Geerlof, A; Kyriakou, E; Lenhart, D; Messias, AC; Pfluger, PT; Pfuhlmann, K; Plettenburg, O; Sattler, M; Schmidt, S; Schramm, KW; Schriever, SC; Simonds, SE; Tiganis, T; Tschöp, MH1
Abdeen, S; Chapman, E; Chitre, S; Hoang, QQ; Johnson, SM; Park, Y; Ray, AM; Salim, N; Sivinski, J; Stevens, M; Washburn, A1
Chen, Z; Hu, C; Huang, Z; Kang, Q; Li, M; Li, X; Li, Z; Lian, B; Peng, S; Su, Y; Yan, S; Yu, H; Zeng, Z; Zhang, D; Zhang, XK; Zhu, Y1
Chen, J; Gao, K; Huang, F; Tepe, JJ; Wang, R; Wei, GW1

Other Studies

7 other study(ies) available for celastrol and triptohypol C

ArticleYear
SARS-CoV 3CLpro inhibitory effects of quinone-methide triterpenes from Tripterygium regelii.
    Bioorganic & medicinal chemistry letters, 2010, Mar-15, Volume: 20, Issue:6

    Topics: Antiviral Agents; Benzoquinones; Models, Molecular; Plant Extracts; Severe acute respiratory syndrome-related coronavirus; Tripterygium; Triterpenes

2010
Novel celastrol derivatives with improved selectivity and enhanced antitumour activity: Design, synthesis and biological evaluation.
    European journal of medicinal chemistry, 2017, Sep-29, Volume: 138

    Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Conformation; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes

2017
Design, synthesis and biological evaluation of novel C-29 carbamate celastrol derivatives as potent and selective cytotoxic compounds.
    European journal of medicinal chemistry, 2017, Oct-20, Volume: 139

    Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Cytotoxins; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes; Tumor Cells, Cultured

2017
Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus.
    Journal of medicinal chemistry, 2018, 12-27, Volume: 61, Issue:24

    Topics: Allosteric Site; Animals; Anti-Obesity Agents; Catalytic Domain; Diet, High-Fat; Hypothalamus; Magnetic Resonance Spectroscopy; Male; Mice, Transgenic; Obesity; Pentacyclic Triterpenes; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 2; Structure-Activity Relationship; Triterpenes; Weight Loss

2018
HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules.
    Bioorganic & medicinal chemistry letters, 2019, 05-01, Volume: 29, Issue:9

    Topics: Biological Products; Chaperonin 10; Chaperonin 60; Escherichia coli; Humans; Inhibitory Concentration 50; Protein Folding; Rafoxanide; Salicylanilides; Suramin

2019
SAR study of celastrol analogs targeting Nur77-mediated inflammatory pathway.
    European journal of medicinal chemistry, 2019, Sep-01, Volume: 177

    Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Drug Design; Hep G2 Cells; Humans; Molecular Docking Simulation; Molecular Structure; Nuclear Receptor Subfamily 4, Group A, Member 1; Pentacyclic Triterpenes; Protein Binding; Sequestosome-1 Protein; Structure-Activity Relationship; TNF Receptor-Associated Factor 2; Triterpenes; Zebrafish

2019
Perspectives on SARS-CoV-2 Main Protease Inhibitors.
    Journal of medicinal chemistry, 2021, 12-09, Volume: 64, Issue:23

    Topics: Antiviral Agents; Coronavirus 3C Proteases; Humans; Protease Inhibitors

2021