celastrol has been researched along with tretinoin in 6 studies
| Studies (celastrol) | Trials (celastrol) | Recent Studies (post-2010) (celastrol) | Studies (tretinoin) | Trials (tretinoin) | Recent Studies (post-2010) (tretinoin) |
|---|---|---|---|---|---|
| 885 | 1 | 741 | 23,654 | 1,083 | 6,085 |
| Protein | Taxonomy | celastrol (IC50) | tretinoin (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.18 | |
| Adenosine receptor A3 | Homo sapiens (human) | 5.275 | |
| Retinoic acid receptor alpha | Homo sapiens (human) | 2.2542 | |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | 5.3 | |
| Retinoic acid receptor beta | Homo sapiens (human) | 0.7537 | |
| Retinoic acid receptor alpha | Mus musculus (house mouse) | 0.0057 | |
| Retinoic acid receptor gamma | Homo sapiens (human) | 0.0064 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.275 | |
| Retinoic acid receptor gamma | Mus musculus (house mouse) | 0.004 | |
| Retinoic acid receptor beta | Mus musculus (house mouse) | 0.005 | |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | 0.576 | |
| Nuclear receptor ROR-alpha | Homo sapiens (human) | 0.1995 | |
| Alpha-synuclein | Homo sapiens (human) | 3 | |
| Cellular retinoic acid-binding protein 1 | Gallus gallus (chicken) | 0.5233 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.358 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.275 | |
| Retinoic acid receptor RXR-gamma | Homo sapiens (human) | 0.35 | |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | 0.1995 | |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | 5.3 | |
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | 0.82 | |
| 60 kDa chaperonin | Escherichia coli | 6.7 | |
| 10 kDa chaperonin | Escherichia coli | 6.7 | |
| Nuclear receptor ROR-beta | Homo sapiens (human) | 0.1259 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Abdeen, S; Chapman, E; Chitre, S; Hoang, QQ; Johnson, SM; Park, Y; Ray, AM; Salim, N; Sivinski, J; Stevens, M; Washburn, A | 1 |
| Liu, XH; Qin, WZ; Uzan, G; Xu, LM; Yang, CX; Zhang, DH | 1 |
| Jantas, D; Konieczny, J; Kuśmierczyk, J; Lasoń, W; Lenda, T; Lorenc-Koci, E; Roman, A | 1 |
| An, HZ; Cao, FF; Peng, B; Uzan, G; Wang, Y; Xu, LM; Xu, XF; Yang, Y; Yu, YZ; Zhang, DH; Zheng, AX; Zheng, YJ | 1 |
| Ethiraj, P; Natarajan, S; Samuel, S; Veerappan, K; Vetrivel, U | 1 |
6 other study(ies) available for celastrol and tretinoin
| Article | Year |
|---|---|
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules.
Topics: Biological Products; Chaperonin 10; Chaperonin 60; Escherichia coli; Humans; Inhibitory Concentration 50; Protein Folding; Rafoxanide; Salicylanilides; Suramin | 2019 |
[Tripterine inhibits all-trans retinoic acid-caused adhesion between leukemia cells and endothelial cells].
Topics: Cell Adhesion; Cell Line; Cell Line, Tumor; E-Selectin; Endothelial Cells; Humans; Intercellular Adhesion Molecule-1; Leukemia, Promyelocytic, Acute; Pentacyclic Triterpenes; Tretinoin; Tripterygium; Triterpenes; Vascular Cell Adhesion Molecule-1 | 2007 |
The extent of neurodegeneration and neuroprotection in two chemical in vitro models related to Parkinson's disease is critically dependent on cell culture conditions.
Topics: Acetylcysteine; Cell Death; Cell Differentiation; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Drug Interactions; Humans; Nerve Degeneration; Neuroprotective Agents; Parkinson Disease; Pentacyclic Triterpenes; Rotenone; Time Factors; Tretinoin; Triterpenes | 2013 |
Celastrol inhibits lung infiltration in differential syndrome animal models by reducing TNF-α and ICAM-1 levels while preserving differentiation in ATRA-induced acute promyelocytic leukemia cells.
Topics: Animals; Cell Differentiation; Cell Line, Tumor; Humans; Intercellular Adhesion Molecule-1; Leukemia, Promyelocytic, Acute; Lung; Male; MAP Kinase Signaling System; Mice; Mice, Inbred NOD; Mice, SCID; Pentacyclic Triterpenes; RNA, Messenger; RNA, Neoplasm; Syndrome; Tretinoin; Triterpenes; Tumor Necrosis Factor-alpha | 2014 |
Inhibition of IKKβ by celastrol and its analogues - an in silico and in vitro approach.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Anti-Inflammatory Agents; Binding Sites; Cell Line, Tumor; Humans; Hydrogen Bonding; I-kappa B Kinase; Molecular Docking Simulation; Neurons; Neuroprotective Agents; Pentacyclic Triterpenes; Peptide Fragments; Phosphorylation; Protein Binding; Protein Conformation; Protein Kinase Inhibitors; Signal Transduction; Structure-Activity Relationship; Tretinoin; Triterpenes | 2017 |