Page last updated: 2024-09-03

celastrol and thymoquinone

celastrol has been researched along with thymoquinone in 2 studies

Compound Research Comparison

Studies (celastrol)	Trials (celastrol)	Recent Studies (post-2010) (celastrol)	Studies (thymoquinone)	Trials (thymoquinone)	Recent Studies (post-2010) (thymoquinone)
885	1	741	1,092	3	888

Protein Interaction Comparison

Protein	Taxonomy	celastrol (IC50)	thymoquinone (IC50)
Caspase-1	Homo sapiens (human)		1.08
Serine/threonine-protein kinase PLK1	Homo sapiens (human)		2.18

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P	1
Dumont, S; Hentsch, D; Kessler, P; Moreira-Tabaka, H; Muller, CD; Peluso, J; Reimund, JM; Vonesch, JL	1

Other Studies

2 other study(ies) available for celastrol and thymoquinone

Article	Year
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22 Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship	2012
Unlike for human monocytes after LPS activation, release of TNF-α by THP-1 cells is produced by a TACE catalytically different from constitutive TACE. PloS one, 2012, Volume: 7, Issue:3 Topics: ADAM Proteins; ADAM17 Protein; Animals; Benzoquinones; Cell Line; Cell Membrane; Chronic Disease; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Hydroxamic Acids; Inflammation; Inhibitory Concentration 50; Lipopolysaccharides; Mice; Microscopy, Confocal; Monocytes; Pentacyclic Triterpenes; Peptide Hydrolases; Recombinant Proteins; Sulfonamides; Triterpenes; Tumor Necrosis Factor-alpha	2012

Article

Year

Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012

Unlike for human monocytes after LPS activation, release of TNF-α by THP-1 cells is produced by a TACE catalytically different from constitutive TACE.

PloS one, 2012, Volume: 7, Issue:3

Topics: ADAM Proteins; ADAM17 Protein; Animals; Benzoquinones; Cell Line; Cell Membrane; Chronic Disease; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Hydroxamic Acids; Inflammation; Inhibitory Concentration 50; Lipopolysaccharides; Mice; Microscopy, Confocal; Monocytes; Pentacyclic Triterpenes; Peptide Hydrolases; Recombinant Proteins; Sulfonamides; Triterpenes; Tumor Necrosis Factor-alpha

2012