Page last updated: 2024-09-03

celastrol and shikonin

celastrol has been researched along with shikonin in 3 studies

Compound Research Comparison

Studies
(celastrol)
Trials
(celastrol)
Recent Studies (post-2010)
(celastrol)
Studies
(shikonin)
Trials
(shikonin)
Recent Studies (post-2010) (shikonin)
88517416602505

Protein Interaction Comparison

ProteinTaxonomycelastrol (IC50)shikonin (IC50)
Epidermal growth factor receptorHomo sapiens (human)0.1392
DNA topoisomerase 2-alphaHomo sapiens (human)6.6
Pyruvate kinase PKMHomo sapiens (human)6.2933
M-phase inducer phosphatase 1Homo sapiens (human)0.22
M-phase inducer phosphatase 2Homo sapiens (human)0.4
DNA topoisomerase 2-betaHomo sapiens (human)6.6
Class A sortase SrtA Staphylococcus aureus2.65

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Dou, QP; Liu, J; Yang, H1

Reviews

1 review(s) available for celastrol and shikonin

ArticleYear
Targeting tumor proteasome with traditional Chinese medicine.
    Current drug discovery technologies, 2010, Volume: 7, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Benzyl Compounds; Curcumin; Diterpenes; Drug Delivery Systems; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Epoxy Compounds; Humans; Medicine, Chinese Traditional; Molecular Structure; Naphthoquinones; Neoplasms; Pentacyclic Triterpenes; Phenanthrenes; Phenols; Proteasome Endopeptidase Complex; Signal Transduction; Triterpenes

2010

Other Studies

2 other study(ies) available for celastrol and shikonin

ArticleYear
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023