Page last updated: 2024-09-03

celastrol and shikonin

celastrol has been researched along with shikonin in 3 studies

Compound Research Comparison

Studies (celastrol)	Trials (celastrol)	Recent Studies (post-2010) (celastrol)	Studies (shikonin)	Trials (shikonin)	Recent Studies (post-2010) (shikonin)
885	1	741	660	2	505

Protein Interaction Comparison

Protein	Taxonomy	shikonin (IC50)
Epidermal growth factor receptor	Homo sapiens (human)	0.1392
DNA topoisomerase 2-alpha	Homo sapiens (human)	6.6
Pyruvate kinase PKM	Homo sapiens (human)	6.2933
M-phase inducer phosphatase 1	Homo sapiens (human)	0.22
M-phase inducer phosphatase 2	Homo sapiens (human)	0.4
DNA topoisomerase 2-beta	Homo sapiens (human)	6.6
Class A sortase SrtA	Staphylococcus aureus	2.65

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (66.67)	24.3611
2020's	1 (33.33)	2.80

Authors

Authors	Studies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Dou, QP; Liu, J; Yang, H	1

Reviews

1 review(s) available for celastrol and shikonin

Article	Year
Targeting tumor proteasome with traditional Chinese medicine. Current drug discovery technologies, 2010, Volume: 7, Issue:1 Topics: Animals; Antineoplastic Agents, Phytogenic; Benzyl Compounds; Curcumin; Diterpenes; Drug Delivery Systems; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Epoxy Compounds; Humans; Medicine, Chinese Traditional; Molecular Structure; Naphthoquinones; Neoplasms; Pentacyclic Triterpenes; Phenanthrenes; Phenols; Proteasome Endopeptidase Complex; Signal Transduction; Triterpenes	2010

Article

Year

Targeting tumor proteasome with traditional Chinese medicine.

Current drug discovery technologies, 2010, Volume: 7, Issue:1

Topics: Animals; Antineoplastic Agents, Phytogenic; Benzyl Compounds; Curcumin; Diterpenes; Drug Delivery Systems; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Epoxy Compounds; Humans; Medicine, Chinese Traditional; Molecular Structure; Naphthoquinones; Neoplasms; Pentacyclic Triterpenes; Phenanthrenes; Phenols; Proteasome Endopeptidase Complex; Signal Transduction; Triterpenes

2010

Other Studies

2 other study(ies) available for celastrol and shikonin

Article	Year
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22 Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship	2012
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023

Article

Year

Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012

In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.

Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023