Page last updated: 2024-09-03

celastrol and semaxinib

celastrol has been researched along with semaxinib in 1 studies

Compound Research Comparison

Studies
(celastrol)
Trials
(celastrol)
Recent Studies (post-2010)
(celastrol)
Studies
(semaxinib)
Trials
(semaxinib)
Recent Studies (post-2010) (semaxinib)
885174148031218

Protein Interaction Comparison

ProteinTaxonomycelastrol (IC50)semaxinib (IC50)
Chain A, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RETHomo sapiens (human)0.17
Chain A, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RETHomo sapiens (human)0.17
Chain A, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RETHomo sapiens (human)0.17
Dihydrofolate reductaseHomo sapiens (human)2.4
Dihydrofolate reductaseMus musculus (house mouse)2.4
Epidermal growth factor receptorHomo sapiens (human)3.592
Platelet-derived growth factor receptor betaMus musculus (house mouse)4.05
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)0.084
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)0.17
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.5
Platelet-derived growth factor receptor betaHomo sapiens (human)2.3563
Mast/stem cell growth factor receptor KitHomo sapiens (human)0.365
Fibroblast growth factor receptor 1Homo sapiens (human)4.865
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.5
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)3.89
Dihydrofolate reductasePneumocystis carinii2.4
Platelet-derived growth factor receptor alphaHomo sapiens (human)0.2
Vascular endothelial growth factor receptor 1 Homo sapiens (human)0.7648
Fibroblast growth factor receptor 2Homo sapiens (human)5
Fibroblast growth factor receptor 4Homo sapiens (human)5
Fibroblast growth factor receptor 3Homo sapiens (human)5
Platelet-derived growth factor receptor alpha Mus musculus (house mouse)4.05
Vascular endothelial growth factor receptor 3Homo sapiens (human)0.275
Vascular endothelial growth factor receptor 2Mus musculus (house mouse)1.04
Vascular endothelial growth factor receptor 2Homo sapiens (human)1.0999
Vascular endothelial growth factor receptor 1Mus musculus (house mouse)1.04
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.16
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.2
Vascular endothelial growth factor receptor 2Danio rerio (zebrafish)0.068
1,25-dihydroxyvitamin D-3 receptor Sus scrofa domesticus (domestic pig)1.04
Dihydrofolate reductaseRattus norvegicus (Norway rat)2.4
ALK tyrosine kinase receptorHomo sapiens (human)1.505

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Kikuchi, N; Kurosawa, R; Miyata, S; Nakata, T; Nogi, M; Omura, J; Satoh, K; Satoh, T; Shimokawa, H; Shindo, T; Siddique, MAH; Sunamura, S; Takeuchi, Y1

Other Studies

1 other study(ies) available for celastrol and semaxinib

ArticleYear
Identification of Celastrol as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension and Right Ventricular Failure Through Suppression of Bsg (Basigin)/CyPA (Cyclophilin A).
    Arteriosclerosis, thrombosis, and vascular biology, 2021, Volume: 41, Issue:3

    Topics: Animals; Antihypertensive Agents; Basigin; Cyclophilin A; Disease Models, Animal; Humans; Hypoxia; Indoles; Mice; Mice, Transgenic; Myocytes, Cardiac; Pentacyclic Triterpenes; Pulmonary Arterial Hypertension; Pyrroles; Rats; Triterpenes; Ventricular Dysfunction, Right

2021