Page last updated: 2024-09-03

celastrol and sanguinarine

celastrol has been researched along with sanguinarine in 2 studies

Compound Research Comparison

Studies (celastrol)	Trials (celastrol)	Recent Studies (post-2010) (celastrol)	Studies (sanguinarine)	Trials (sanguinarine)	Recent Studies (post-2010) (sanguinarine)
885	1	741	675	37	290

Protein Interaction Comparison

Protein	Taxonomy	sanguinarine (IC50)
Cholinesterase	Homo sapiens (human)	7.08
Nuclear factor NF-kappa-B p105 subunit	Homo sapiens (human)	2
Acetylcholinesterase	Homo sapiens (human)	1.22
Nuclear factor NF-kappa-B p100 subunit	Homo sapiens (human)	2
Transcription factor p65	Homo sapiens (human)	2

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P	1
Bodle, CR; Doorn, JA; Hayes, MP; Henry, MD; Houtman, JCD; James, MA; Mackie, DI; Miller, MR; Roman, DL; Schamp, JH	1

Other Studies

2 other study(ies) available for celastrol and sanguinarine

Article	Year
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22 Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship	2012
Natural Products Discovered in a High-Throughput Screen Identified as Inhibitors of RGS17 and as Cytostatic and Cytotoxic Agents for Lung and Prostate Cancer Cell Lines. Journal of natural products, 2017, 07-28, Volume: 80, Issue:7 Topics: Benzophenanthridines; Biological Products; Cytostatic Agents; Cytotoxins; GTP-Binding Protein Regulators; Humans; Isoquinolines; Lung Neoplasms; Male; Molecular Structure; Pentacyclic Triterpenes; Prostatic Neoplasms; Triterpenes	2017

Article

Year

Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012

Natural Products Discovered in a High-Throughput Screen Identified as Inhibitors of RGS17 and as Cytostatic and Cytotoxic Agents for Lung and Prostate Cancer Cell Lines.

Journal of natural products, 2017, 07-28, Volume: 80, Issue:7

Topics: Benzophenanthridines; Biological Products; Cytostatic Agents; Cytotoxins; GTP-Binding Protein Regulators; Humans; Isoquinolines; Lung Neoplasms; Male; Molecular Structure; Pentacyclic Triterpenes; Prostatic Neoplasms; Triterpenes

2017