celastrol has been researched along with rotenone in 4 studies
| Studies (celastrol) | Trials (celastrol) | Recent Studies (post-2010) (celastrol) | Studies (rotenone) | Trials (rotenone) | Recent Studies (post-2010) (rotenone) |
|---|---|---|---|---|---|
| 885 | 1 | 741 | 4,407 | 6 | 1,648 |
| Protein | Taxonomy | celastrol (IC50) | rotenone (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 8 | |
| NADH-ubiquinone oxidoreductase chain 1 | Bos taurus (cattle) | 0.015 | |
| NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | Bos taurus (cattle) | 0.0051 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 3.6486 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.87 | |
| Acyl carrier protein, mitochondrial | Bos taurus (cattle) | 0.0051 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Jantas, D; Konieczny, J; Kuśmierczyk, J; Lasoń, W; Lenda, T; Lorenc-Koci, E; Roman, A | 1 |
| Deng, YN; Liu, J; Qu, QM; Shi, J | 1 |
| Choi, BS; Kim, H; Kim, S; Kim, SJ; Lee, HJ; Park, SE; Sapkota, K | 1 |
4 other study(ies) available for celastrol and rotenone
| Article | Year |
|---|---|
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
The extent of neurodegeneration and neuroprotection in two chemical in vitro models related to Parkinson's disease is critically dependent on cell culture conditions.
Topics: Acetylcysteine; Cell Death; Cell Differentiation; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Drug Interactions; Humans; Nerve Degeneration; Neuroprotective Agents; Parkinson Disease; Pentacyclic Triterpenes; Rotenone; Time Factors; Tretinoin; Triterpenes | 2013 |
Celastrol protects human neuroblastoma SH-SY5Y cells from rotenone-induced injury through induction of autophagy.
Topics: Apoptosis; Autophagy; Cell Line, Tumor; Humans; Neuroblastoma; Pentacyclic Triterpenes; Rotenone; Triterpenes | 2013 |
Celastrol from 'Thunder God Vine' protects SH-SY5Y cells through the preservation of mitochondrial function and inhibition of p38 MAPK in a rotenone model of Parkinson's disease.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Humans; Membrane Potential, Mitochondrial; Neuroprotective Agents; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Parkinson Disease; Pentacyclic Triterpenes; Rotenone; Triterpenes | 2014 |