Page last updated: 2024-09-03

celastrol and resveratrol

celastrol has been researched along with resveratrol in 7 studies

Compound Research Comparison

Studies
(celastrol)
Trials
(celastrol)
Recent Studies (post-2010)
(celastrol)
Studies
(resveratrol)
Trials
(resveratrol)
Recent Studies (post-2010) (resveratrol)
885174110,9312417,998

Protein Interaction Comparison

ProteinTaxonomycelastrol (IC50)resveratrol (IC50)
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
M18 aspartyl aminopeptidasePlasmodium falciparum 3D72.242
VifHuman immunodeficiency virus 125.31
DNA dC->dU-editing enzyme APOBEC-3G isoform 1Homo sapiens (human)25.31
Transient receptor potential cation channel subfamily A member 1Homo sapiens (human)0.75
Amyloid-beta precursor proteinHomo sapiens (human)2.6
Cytochrome P450 1A2Homo sapiens (human)3
Prostaglandin G/H synthase 1Ovis aries (sheep)2.025
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)2.312
Luciferin 4-monooxygenasePhotinus pyralis (common eastern firefly)0.0589
Cytochrome P450 3A4Homo sapiens (human)0.6
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.685
DNA polymerase alpha catalytic subunitHomo sapiens (human)3.3
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)4.9
AromataseHomo sapiens (human)0.96
Cytochrome P450 2C9 Homo sapiens (human)7
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.685
TyrosinaseHomo sapiens (human)5.35
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)1.3972
Nuclear factor NF-kappa-B p105 subunitHomo sapiens (human)2.5
Amine oxidase [flavin-containing] AHomo sapiens (human)2.4945
Prostaglandin G/H synthase 1Homo sapiens (human)0.8517
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.312
Amine oxidase [flavin-containing] BHomo sapiens (human)5.01
Dipeptidyl peptidase 4Homo sapiens (human)0.0006
Cytochrome P450 2C19Homo sapiens (human)3
Prostaglandin G/H synthase 2Homo sapiens (human)1.672
Prostaglandin G/H synthase 2Ovis aries (sheep)3.49
Nuclear factor NF-kappa-B p100 subunit Homo sapiens (human)2.5
Transcription factor p65Homo sapiens (human)2.5
Cytochrome P450 1B1Homo sapiens (human)1.4
Transient receptor potential cation channel subfamily A member 1Rattus norvegicus (Norway rat)1.63
large T antigenBetapolyomavirus macacae26.2

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (42.86)24.3611
2020's4 (57.14)2.80

Authors

AuthorsStudies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Aragonès, G; Ardid-Ruiz, A; Bladé, C; Ibars, M; Suárez, M1
Bedard, K; Chen, PL; Greenshields, AL; Hoskin, DW; Nightingale, M; Whitehouse, S1
Bao, B; Bao, C; Elango, J; Hou, C; Ur Rahman, S; Wang, R; Wang, S; Wu, W1
Akter, R; Bibi, P; Hassan, SSU; Mubin, S; Najda, A; Rahman, MH; Saeeda, S; Shah, M; Wesołowska, S1
Jin, H; Sun, K; Xing, Y; Yu, F; Zhao, W; Zheng, X1

Reviews

2 review(s) available for celastrol and resveratrol

ArticleYear
Modulation of leptin resistance by food compounds.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:8

    Topics: Agouti-Related Protein; Animals; Blood-Brain Barrier; Caffeine; Eating; Food; Hypothalamus; Leptin; Low Density Lipoprotein Receptor-Related Protein-2; Neurons; Neuropeptide Y; Obesity; Pentacyclic Triterpenes; Pro-Opiomelanocortin; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Receptors, Leptin; Resveratrol; Saponins; Stilbenes; Taurine; Triterpenes

2016
Potential Role of Natural Products to Combat Radiotherapy and Their Future Perspectives.
    Molecules (Basel, Switzerland), 2021, Oct-02, Volume: 26, Issue:19

    Topics: Berberine; Biological Products; Curcumin; Emodin; Genistein; Humans; Neoplasms; Pentacyclic Triterpenes; Radiation-Protective Agents; Radiation-Sensitizing Agents; Radiotherapy; Resveratrol; Sesquiterpenes; Triterpenes; Ursolic Acid; Vitamin D; Withanolides

2021

Other Studies

5 other study(ies) available for celastrol and resveratrol

ArticleYear
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Resveratrol, piperine and apigenin differ in their NADPH-oxidase inhibitory and reactive oxygen species-scavenging properties.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2016, Nov-15, Volume: 23, Issue:12

    Topics: Alkaloids; Antioxidants; Apigenin; Benzodioxoles; Cell Line; Humans; Hydrogen Peroxide; NADP; NADPH Oxidases; Oxidation-Reduction; Pentacyclic Triterpenes; Piperidines; Plant Extracts; Polyunsaturated Alkamides; Reactive Oxygen Species; Resveratrol; Stilbenes; Triterpenes

2016
Resveratrol and Celastrol Loaded Collagen Dental Implants Regulate Periodontal Ligament Fibroblast Growth and Osteoclastogenesis of Bone Marrow Macrophages.
    Chemistry & biodiversity, 2020, Volume: 17, Issue:9

    Topics: Antioxidants; Biphenyl Compounds; Bone Marrow; Cell Proliferation; Cells, Cultured; Collagen; Dental Implants; Dose-Response Relationship, Drug; Fibroblasts; Humans; Macrophages; Molecular Structure; Osteogenesis; Pentacyclic Triterpenes; Periodontal Ligament; Picrates; Resveratrol; Structure-Activity Relationship

2020
Combination Therapy with Resveratrol and Celastrol Using Folic Acid-Functionalized Exosomes Enhances the Therapeutic Efficacy of Sepsis.
    Advanced healthcare materials, 2023, Volume: 12, Issue:29

    Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Exosomes; Folic Acid; Lipopolysaccharides; Mice; Pentacyclic Triterpenes; Resveratrol; Sepsis

2023