Compounds > celastrol
Page last updated: 2024-09-03

celastrol and parthenolide

celastrol has been researched along with parthenolide in 4 studies

Compound Research Comparison

Studies
(celastrol)		Trials
(celastrol)		Recent Studies (post-2010)
(celastrol)		Studies
(parthenolide)		Trials
(parthenolide)		Recent Studies (post-2010) (parthenolide)
88517416125323

Protein Interaction Comparison

ProteinTaxonomycelastrol (IC50)parthenolide (IC50)
Nitric oxide synthase, inducibleMus musculus (house mouse)4.525
Prostaglandin G/H synthase 2Homo sapiens (human)0.8

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Abboud, R; Carroll, M; Corbett, C; Guzman, ML; Hassane, DC; Jordan, CT; Li, X; Liesveld, JL; Young, F1
Idris, AI; Krishnan, M; Landao-Bassonga, E; Mollat, P; Ralston, SH; Simic, P; Vukicevic, S1
Chen, X; Li, M; Liu, C; Luo, Q; Qiu, F; Sun, X; Tao, Y1

Other Studies

4 other study(ies) available for celastrol and parthenolide

ArticleYear
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data.
    Blood, 2008, Jun-15, Volume: 111, Issue:12

    Topics: Aldehydes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Death; Cysteine Proteinase Inhibitors; Databases, Genetic; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID; Models, Genetic; Neoplastic Stem Cells; Oligonucleotide Array Sequence Analysis; Pentacyclic Triterpenes; Sesquiterpenes; Terpenes; Triterpenes; Xenograft Model Antitumor Assays

2008
Small molecule inhibitors of IkappaB kinase signaling inhibit osteoclast formation in vitro and prevent ovariectomy-induced bone loss in vivo.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2010, Volume: 24, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Resorption; Cell Differentiation; Cell Survival; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Female; Humans; I-kappa B Kinase; Imidazoles; Inhibitory Concentration 50; Mice; Osteoclasts; Ovariectomy; Pentacyclic Triterpenes; Quinoxalines; Sesquiterpenes; Signal Transduction; Triterpenes

2010
Screening of major hepatotoxic components of Tripterygium wilfordii based on hepatotoxic injury patterns.
    BMC complementary medicine and therapies, 2023, Jan-10, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Mice; RNA, Messenger; Tripterygium; Tumor Necrosis Factor-alpha; Zebrafish

2023