Page last updated: 2024-09-03

celastrol and oleanolic acid

celastrol has been researched along with oleanolic acid in 5 studies

Compound Research Comparison

Studies
(celastrol)
Trials
(celastrol)
Recent Studies (post-2010)
(celastrol)
Studies
(oleanolic acid)
Trials
(oleanolic acid)
Recent Studies (post-2010) (oleanolic acid)
88517414,169312,404

Protein Interaction Comparison

ProteinTaxonomycelastrol (IC50)oleanolic acid (IC50)
Aldo-keto reductase family 1 member B10Homo sapiens (human)2.045
Phospholipase A2Homo sapiens (human)3
DNA polymerase betaHomo sapiens (human)6.8667
DNA polymerase betaRattus norvegicus (Norway rat)5.6
Receptor-type tyrosine-protein phosphatase CHomo sapiens (human)1
Receptor-type tyrosine-protein phosphatase FHomo sapiens (human)3.065
Tissue factorHomo sapiens (human)0.005
Tyrosine-protein phosphatase non-receptor type 2Homo sapiens (human)4.38
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)2.8444
Liver carboxylesterase 1Homo sapiens (human)0.1
Tyrosine-protein phosphatase non-receptor type 6Homo sapiens (human)3.065
M-phase inducer phosphatase 2Homo sapiens (human)0.98
Dual specificity protein phosphatase 3Homo sapiens (human)5.4
Transcription factor p65Homo sapiens (human)2.4
Tyrosine-protein phosphatase non-receptor type 11Homo sapiens (human)3.065
Protease Human immunodeficiency virus 18

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Alho, DPS; Figueiredo, SAC; Gonçalves, BMF; Leal, AS; Mendes, VIS; Salvador, JAR; Silvestre, SM; Valdeira, AS1
Chang, YH; Hung, HY1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Bishayee, A; Deshmukh, RR; Kumar, P; Kumar, S; Sharma, H1

Reviews

3 review(s) available for celastrol and oleanolic acid

ArticleYear
Oleanane-, ursane-, and quinone methide friedelane-type triterpenoid derivatives: Recent advances in cancer treatment.
    European journal of medicinal chemistry, 2017, Dec-15, Volume: 142

    Topics: Animals; Antineoplastic Agents; Chemistry Techniques, Synthetic; Humans; Indolequinones; Neoplasms; Oleanolic Acid; Structure-Activity Relationship; Triterpenes

2017
Recent advances in natural anti-obesity compounds and derivatives based on in vivo evidence: A mini-review.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Animals; Anti-Obesity Agents; Drug Discovery; Obesity; Phytochemicals

2022
Pentacyclic triterpenes: New tools to fight metabolic syndrome.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2018, Nov-15, Volume: 50

    Topics: Animals; Heart; Humans; Insulin Resistance; Liver; Metabolic Syndrome; Muscle, Skeletal; Oleanolic Acid; Oxidative Stress; Pentacyclic Triterpenes; Triterpenes; Ursolic Acid

2018

Other Studies

2 other study(ies) available for celastrol and oleanolic acid

ArticleYear
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023