celastrol has been researched along with monorden in 3 studies
Studies (celastrol) | Trials (celastrol) | Recent Studies (post-2010) (celastrol) | Studies (monorden) | Trials (monorden) | Recent Studies (post-2010) (monorden) |
---|---|---|---|---|---|
885 | 1 | 741 | 341 | 0 | 99 |
Protein | Taxonomy | celastrol (IC50) | monorden (IC50) |
---|---|---|---|
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1 | Homo sapiens (human) | 400 | |
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3 | Homo sapiens (human) | 400 | |
ATP-dependent molecular chaperone HSP82 | Saccharomyces cerevisiae S288C | 0.1193 | |
Heat shock protein HSP 90-alpha | Homo sapiens (human) | 0.2092 | |
Heat shock protein HSP 90-beta | Homo sapiens (human) | 0.1148 | |
ATP-dependent molecular chaperone HSC82 | Saccharomyces cerevisiae S288C | 0.2 | |
Carbonyl reductase [NADPH] 1 | Homo sapiens (human) | 3.27 | |
Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.027 | |
Proto-oncogene tyrosine-protein kinase Src | Rattus norvegicus (Norway rat) | 0.18 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 2 (66.67) | 2.80 |
Authors | Studies |
---|---|
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
Li, L; Wang, L; Xu, XL; You, QD | 1 |
Basilico, N; Bassanini, I; Ferrandi, EE; Gabriele, E; Parapini, S; Sparatore, A; Taramelli, D | 1 |
1 review(s) available for celastrol and monorden
Article | Year |
---|---|
Heat Shock Protein 90 Inhibitors: An Update on Achievements, Challenges, and Future Directions.
Topics: Animals; Antineoplastic Agents; Autoimmune Diseases; Benzoquinones; Forecasting; HSP90 Heat-Shock Proteins; Humans; Immunosuppressive Agents; Lactams, Macrocyclic; Molecular Chaperones; Neoplasms; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary | 2020 |
2 other study(ies) available for celastrol and monorden
Article | Year |
---|---|
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Design, Synthesis and In Vitro Investigation of Novel Basic Celastrol Carboxamides as Bio-Inspired Leishmanicidal Agents Endowed with Inhibitory Activity against
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amides; Animals; Antiprotozoal Agents; Benzoquinones; HSP90 Heat-Shock Proteins; Humans; Kinetics; Lactams, Macrocyclic; Leishmania braziliensis; Macrolides; Mice, Inbred C57BL; Pentacyclic Triterpenes; Protein Conformation; THP-1 Cells | 2021 |