Page last updated: 2024-09-03

celastrol and mocetinostat

celastrol has been researched along with mocetinostat in 4 studies

Compound Research Comparison

Studies
(celastrol)
Trials
(celastrol)
Recent Studies (post-2010)
(celastrol)
Studies
(mocetinostat)
Trials
(mocetinostat)
Recent Studies (post-2010) (mocetinostat)
885174121,7353908,606

Protein Interaction Comparison

ProteinTaxonomycelastrol (IC50)mocetinostat (IC50)
Histone deacetylase 3Homo sapiens (human)0.7851
Nuclear receptor corepressor 1Homo sapiens (human)0.022
Cytochrome P450 3A4Homo sapiens (human)0.57
Cytochrome P450 2D6Homo sapiens (human)0.102
Cytochrome P450 2C19Homo sapiens (human)0.102
Histone deacetylase 4Homo sapiens (human)0.5717
Histone deacetylase 1Homo sapiens (human)0.3433
Histone deacetylase 7Homo sapiens (human)0.6725
Histone deacetylase 2Homo sapiens (human)0.3537
Histone deacetylase 11 Homo sapiens (human)0.6386
Histone deacetylase 8Homo sapiens (human)0.6725
Histone deacetylase 6Homo sapiens (human)0.5717
Histone deacetylase 5Homo sapiens (human)0.6725
Nuclear receptor corepressor 2Homo sapiens (human)0.045

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Chu, C; Gou, X; He, W; Kuang, Y; Ren, K1
Dong, JN; Gong, JF; Gu, LL; Li, JS; Li, N; Li, Y; Shi, P; Sun, Y; Wang, HG; Zhao, J; Zhu, WM; Zuo, LG1
El-Agamy, DS; El-Kashef, DH; Hamed, MF; Shaaban, AA1

Other Studies

4 other study(ies) available for celastrol and mocetinostat

ArticleYear
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Celastrol protects kidney against ischemia-reperfusion-induced injury in rats.
    The Journal of surgical research, 2014, Volume: 186, Issue:1

    Topics: Animals; Cyclooxygenase 2; Intercellular Adhesion Molecule-1; Kidney; Male; Nitric Oxide Synthase Type II; Pentacyclic Triterpenes; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Triterpenes

2014
Celastrol ameliorates experimental colitis in IL-10 deficient mice via the up-regulation of autophagy.
    International immunopharmacology, 2015, Volume: 26, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Autophagy; Blotting, Western; Colon; Crohn Disease; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Interleukin-10; Mice, Inbred C57BL; Mice, Knockout; Pentacyclic Triterpenes; Peroxidase; Real-Time Polymerase Chain Reaction; Signal Transduction; TOR Serine-Threonine Kinases; Triterpenes

2015
Protective effect of pristimerin against LPS-induced acute lung injury in mice.
    International immunopharmacology, 2018, Volume: 59

    Topics: Acute Lung Injury; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Caspase 3; Cell Count; Interleukin-6; L-Lactate Dehydrogenase; Lipopolysaccharides; Lung; Male; Mice; Oxidative Stress; Pentacyclic Triterpenes; Peroxidase; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Triterpenes; Tumor Necrosis Factor-alpha

2018