celastrol has been researched along with mocetinostat in 4 studies
Studies (celastrol) | Trials (celastrol) | Recent Studies (post-2010) (celastrol) | Studies (mocetinostat) | Trials (mocetinostat) | Recent Studies (post-2010) (mocetinostat) |
---|---|---|---|---|---|
885 | 1 | 741 | 21,735 | 390 | 8,606 |
Protein | Taxonomy | celastrol (IC50) | mocetinostat (IC50) |
---|---|---|---|
Histone deacetylase 3 | Homo sapiens (human) | 0.7851 | |
Nuclear receptor corepressor 1 | Homo sapiens (human) | 0.022 | |
Cytochrome P450 3A4 | Homo sapiens (human) | 0.57 | |
Cytochrome P450 2D6 | Homo sapiens (human) | 0.102 | |
Cytochrome P450 2C19 | Homo sapiens (human) | 0.102 | |
Histone deacetylase 4 | Homo sapiens (human) | 0.5717 | |
Histone deacetylase 1 | Homo sapiens (human) | 0.3433 | |
Histone deacetylase 7 | Homo sapiens (human) | 0.6725 | |
Histone deacetylase 2 | Homo sapiens (human) | 0.3537 | |
Histone deacetylase 11 | Homo sapiens (human) | 0.6386 | |
Histone deacetylase 8 | Homo sapiens (human) | 0.6725 | |
Histone deacetylase 6 | Homo sapiens (human) | 0.5717 | |
Histone deacetylase 5 | Homo sapiens (human) | 0.6725 | |
Nuclear receptor corepressor 2 | Homo sapiens (human) | 0.045 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 3 (75.00) | 24.3611 |
2020's | 1 (25.00) | 2.80 |
Authors | Studies |
---|---|
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
Chu, C; Gou, X; He, W; Kuang, Y; Ren, K | 1 |
Dong, JN; Gong, JF; Gu, LL; Li, JS; Li, N; Li, Y; Shi, P; Sun, Y; Wang, HG; Zhao, J; Zhu, WM; Zuo, LG | 1 |
El-Agamy, DS; El-Kashef, DH; Hamed, MF; Shaaban, AA | 1 |
4 other study(ies) available for celastrol and mocetinostat
Article | Year |
---|---|
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Celastrol protects kidney against ischemia-reperfusion-induced injury in rats.
Topics: Animals; Cyclooxygenase 2; Intercellular Adhesion Molecule-1; Kidney; Male; Nitric Oxide Synthase Type II; Pentacyclic Triterpenes; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Triterpenes | 2014 |
Celastrol ameliorates experimental colitis in IL-10 deficient mice via the up-regulation of autophagy.
Topics: Animals; Anti-Inflammatory Agents; Autophagy; Blotting, Western; Colon; Crohn Disease; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Interleukin-10; Mice, Inbred C57BL; Mice, Knockout; Pentacyclic Triterpenes; Peroxidase; Real-Time Polymerase Chain Reaction; Signal Transduction; TOR Serine-Threonine Kinases; Triterpenes | 2015 |
Protective effect of pristimerin against LPS-induced acute lung injury in mice.
Topics: Acute Lung Injury; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Caspase 3; Cell Count; Interleukin-6; L-Lactate Dehydrogenase; Lipopolysaccharides; Lung; Male; Mice; Oxidative Stress; Pentacyclic Triterpenes; Peroxidase; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Triterpenes; Tumor Necrosis Factor-alpha | 2018 |