celastrol has been researched along with leupeptins in 10 studies
| Studies (celastrol) | Trials (celastrol) | Recent Studies (post-2010) (celastrol) | Studies (leupeptins) | Trials (leupeptins) | Recent Studies (post-2010) (leupeptins) |
|---|---|---|---|---|---|
| 885 | 1 | 741 | 3,891 | 4 | 1,106 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 7 (70.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balch, WE; Kelly, JW; Mu, TW; Ong, DS; Segatori, L; Wang, YJ; Yates, JR | 1 |
| Heikkila, JJ; Walcott, SE | 1 |
| Brunt, JJ; Heikkila, JJ; Khan, S | 1 |
| Jiang, ZZ; Li, H; Mu, XM; Shi, W; Sun, LX; Wang, YR; Zhang, LY | 1 |
| Igdoura, SA; O'Leary, EM | 1 |
| Babajani, G; Kermode, AR | 1 |
| Heikkila, JJ; Khamis, I; Khan, S; Music, E | 1 |
| Ishikawa, Y; Sakurai, H | 1 |
| Xiao, Y | 1 |
| Desviat, LR; Gallego, D; Gámez, A; Pérez, B; Pérez-Cerda, C; Ugarte, M; Vilas, A; Yuste-Checa, P | 1 |
10 other study(ies) available for celastrol and leupeptins
| Article | Year |
|---|---|
Chemical and biological approaches synergize to ameliorate protein-folding diseases.
Topics: Cell Line; Fibroblasts; Gaucher Disease; Humans; Leupeptins; Lysosomal Storage Diseases; Molecular Chaperones; Pentacyclic Triterpenes; Protein Folding; Proteins; Tay-Sachs Disease; Triterpenes | 2008 |
Celastrol can inhibit proteasome activity and upregulate the expression of heat shock protein genes, hsp30 and hsp70, in Xenopus laevis A6 cells.
Topics: Animals; Benzhydryl Compounds; DNA-Binding Proteins; Epithelial Cells; Heat Shock Transcription Factors; Heat-Shock Response; HSP30 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Leupeptins; Pentacyclic Triterpenes; Proteasome Inhibitors; Protein Transport; Pyrrolidinones; Transcription Factors; Triterpenes; Up-Regulation; Xenopus laevis; Xenopus Proteins | 2010 |
Sodium arsenite and cadmium chloride induction of proteasomal inhibition and HSP accumulation in Xenopus laevis A6 kidney epithelial cells.
Topics: Animals; Arsenites; Benzhydryl Compounds; Cadmium Chloride; Cell Line; Chymotrypsin; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Environmental Pollutants; Epithelial Cells; Heat-Shock Proteins; HSP30 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Immunoblotting; Kidney; Leupeptins; Pentacyclic Triterpenes; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrrolidinones; Sodium Compounds; Time Factors; Triterpenes; Ubiquitinated Proteins; Ubiquitination; Xenopus laevis; Xenopus Proteins | 2012 |
Pristimerin inhibits breast cancer cell migration by up- regulating regulator of G protein signaling 4 expression.
Topics: Actins; Analysis of Variance; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Chymases; Dose-Response Relationship, Drug; Female; Humans; Leupeptins; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Pentacyclic Triterpenes; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Random Allocation; RGS Proteins; RNA Interference; Triterpenes; Tumor Burden; Up-Regulation | 2012 |
The therapeutic potential of pharmacological chaperones and proteosomal inhibitors, Celastrol and MG132 in the treatment of sialidosis.
Topics: Cell Line; Cysteine Proteinase Inhibitors; Enzyme Activation; Fibroblasts; Gangliosides; Gene Expression Regulation; Humans; Leupeptins; Lysosomal-Associated Membrane Protein 2; Mucolipidoses; Mutation; Neuraminidase; Pentacyclic Triterpenes; Protein Binding; Protein Transport; Triterpenes | 2012 |
Alteration of the proteostasis network of plant cells promotes the post-endoplasmic reticulum trafficking of recombinant mutant (L444P) human β-glucocerebrosidase.
Topics: Alkaloids; Cell Line; Endoplasmic Reticulum; Endoplasmic Reticulum-Associated Degradation; Gene Expression Profiling; Glucosylceramidase; Glycoside Hydrolases; HSP90 Heat-Shock Proteins; Humans; Hydrazones; Hydroxyurea; Leupeptins; Molecular Chaperones; Molecular Sequence Data; Mutation, Missense; Nicotiana; Pentacyclic Triterpenes; Plant Cells; Plants, Genetically Modified; Proteasome Inhibitors; Protein Transport; Protoplasts; Recombinant Proteins; Triterpenes | 2014 |
Accumulation of heme oxygenase-1 (HSP32) in Xenopus laevis A6 kidney epithelial cells treated with sodium arsenite, cadmium chloride or proteasomal inhibitors.
Topics: Animals; Arsenites; Cadmium Chloride; Cell Line; Cytoplasmic Structures; Enzyme Induction; Heme Oxygenase-1; Hot Temperature; HSP30 Heat-Shock Proteins; Immunohistochemistry; Kidney; Leupeptins; Pentacyclic Triterpenes; Proteasome Inhibitors; Protein Transport; Sodium Compounds; Toxicity Tests, Acute; Triterpenes; Water Pollutants, Chemical; Withanolides; Xenopus laevis; Xenopus Proteins | 2014 |
Heat-induced expression of the immediate-early gene IER5 and its involvement in the proliferation of heat-shocked cells.
Topics: Cell Proliferation; DNA-Binding Proteins; Gene Expression Regulation; Heat Shock Transcription Factors; Heat-Shock Response; HeLa Cells; Hot Temperature; Humans; Immediate-Early Proteins; Leupeptins; Molecular Chaperones; Nuclear Proteins; Pentacyclic Triterpenes; Promoter Regions, Genetic; RNA, Messenger; Transcription Factors; Transcription, Genetic; Triterpenes | 2015 |
Construction of a circRNA-miRNA-mRNA network to explore the pathogenesis and treatment of pancreatic ductal adenocarcinoma.
Topics: Antineoplastic Agents; Carcinoma, Pancreatic Ductal; Computational Biology; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; HL-60 Cells; Humans; Imidazoles; Leupeptins; MicroRNAs; Oligonucleotide Array Sequence Analysis; Pancreatic Neoplasms; Pentacyclic Triterpenes; Phosphorylation; Protein Interaction Maps; RNA, Circular; RNA, Messenger; Software; Treatment Outcome; Triterpenes | 2020 |
Proteostasis regulators as potential rescuers of PMM2 activity.
Topics: Congenital Disorders of Glycosylation; Fibroblasts; Glycosylation; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Leupeptins; Mutation; Pentacyclic Triterpenes; Phosphotransferases (Phosphomutases); Protein Folding; Proteostasis; Triterpenes | 2020 |