celastrol has been researched along with leptin in 8 studies
| Studies (celastrol) | Trials (celastrol) | Recent Studies (post-2010) (celastrol) | Studies (leptin) | Trials (leptin) | Recent Studies (post-2010) (leptin) |
|---|---|---|---|---|---|
| 885 | 1 | 741 | 25,940 | 1,628 | 11,468 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, J; Liu, J; Mazitschek, R; Ozcan, U; Salazar Hernandez, MA | 1 |
| Aragonès, G; Ardid-Ruiz, A; Bladé, C; Ibars, M; Suárez, M | 1 |
| Cai, F; Liu, L; Liu, X; Yang, A; Zhang, Y | 1 |
| Choi, JW; Feng, X; Ibi, D; Lee, J; Liu, J; Mucka, P; Ozcan, U; Salazar Hernández, MA | 1 |
| Baur, JA; Chellappa, K; Naidoo, N; Perron, IJ | 1 |
| Auen, T; Choi, JW; Chun, H; Copps, KD; Faruk, F; Feng, X; Guan, D; Herbert, Z; Kaplun, E; Lee, J; Ozcan, U; Salazar Hernández, MA | 1 |
| Afrin, S; Cao, J; Chau, D; Cheng, B; Dong, Y; Gao, Y; He, Z; Hu, L; Huang, Y; Hwang, ES; Kabahizi, A; Lieu, L; Okolo, J; Wallace, B; Williams, KW; Yao, T | 1 |
| Cifre, M; Oliver, P; Palou, A; Reynés, B | 1 |
1 review(s) available for celastrol and leptin
| Article | Year |
|---|---|
Modulation of leptin resistance by food compounds.
Topics: Agouti-Related Protein; Animals; Blood-Brain Barrier; Caffeine; Eating; Food; Hypothalamus; Leptin; Low Density Lipoprotein Receptor-Related Protein-2; Neurons; Neuropeptide Y; Obesity; Pentacyclic Triterpenes; Pro-Opiomelanocortin; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Receptors, Leptin; Resveratrol; Saponins; Stilbenes; Taurine; Triterpenes | 2016 |
7 other study(ies) available for celastrol and leptin
| Article | Year |
|---|---|
Treatment of obesity with celastrol.
Topics: Animals; Anti-Obesity Agents; Energy Metabolism; Gene Expression Profiling; Glucose; Hypothalamus; Leptin; Mice; Obesity; Pentacyclic Triterpenes; Plant Extracts; Tripterygium; Triterpenes | 2015 |
Celastrol, an NF-κB inhibitor, ameliorates hypercalciuria and articular cartilage lesions in a mouse model of secondary osteoporosis.
Topics: Adipose Tissue; Animals; Body Weight; Cartilage, Articular; Disease Models, Animal; Disease Progression; Hypercalciuria; Leptin; Lipid Metabolism; Male; Mice, Inbred C57BL; Molecular Targeted Therapy; NF-kappa B; Osteoporosis; Parathyroid Hormone; Pentacyclic Triterpenes; Triterpenes | 2016 |
Withaferin A is a leptin sensitizer with strong antidiabetic properties in mice.
Topics: Animals; Blood Glucose; Blotting, Western; Body Weight; Diabetes Mellitus, Type 2; Diet, High-Fat; Fatty Liver; Fluorescent Antibody Technique; Glucose Tolerance Test; Hypothalamus; Immunohistochemistry; Leptin; Liver; Mice; Mice, Obese; Obesity; Pentacyclic Triterpenes; Real-Time Polymerase Chain Reaction; Signal Transduction; STAT3 Transcription Factor; Triterpenes; Withanolides | 2016 |
The leptin sensitizer celastrol reduces age-associated obesity and modulates behavioral rhythms.
Topics: Aging; Animals; Behavior, Animal; Body Weight; Circadian Rhythm; Eating; Energy Metabolism; Glucose Tolerance Test; Injections, Intraperitoneal; Leptin; Male; Mice; Obesity; Pentacyclic Triterpenes; Triterpenes; Weight Loss | 2019 |
IL1R1 is required for celastrol's leptin-sensitization and antiobesity effects.
Topics: Animals; Anti-Obesity Agents; Diet; HEK293 Cells; Humans; Interleukin 1 Receptor Antagonist Protein; Leptin; Male; Mice, Inbred C57BL; Mice, Knockout; Obesity; Pentacyclic Triterpenes; Receptors, Interleukin-1 Type I; Triterpenes | 2019 |
PERK in POMC neurons connects celastrol with metabolism.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Body Weight; Diet, High-Fat; Eating; eIF-2 Kinase; Endoplasmic Reticulum Stress; Energy Metabolism; Glucose; Insulin Resistance; Leptin; Male; Mice; Mice, Knockout; Neurons; Obesity; Pentacyclic Triterpenes; Pro-Opiomelanocortin | 2021 |
Perinatal Treatment with Leptin, but Not Celastrol, Protects from Metabolically Obese, Normal-Weight Phenotype in Rats.
Topics: Animals; Body Weight; Diet, High-Fat; Dietary Fats; Female; Insulin; Leptin; Obesity; Pentacyclic Triterpenes; Phenotype; Pregnancy; Rats | 2022 |