celastrol has been researched along with irinotecan in 2 studies
| Studies (celastrol) | Trials (celastrol) | Recent Studies (post-2010) (celastrol) | Studies (irinotecan) | Trials (irinotecan) | Recent Studies (post-2010) (irinotecan) |
|---|---|---|---|---|---|
| 885 | 1 | 741 | 8,002 | 1,885 | 3,752 |
| Protein | Taxonomy | celastrol (IC50) | irinotecan (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 2 | Homo sapiens (human) | 2.7 | |
| Interstitial collagenase | Homo sapiens (human) | 6.06 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 1.556 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 3.171 | |
| Acetylcholinesterase | Homo sapiens (human) | 1.827 | |
| Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | 7.9 | |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 4.7667 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, HG; Gautam, M; Jin, SG; Kim, JO; Ku, SK; Nguyen, HT; Oh, KT; Ou, W; Soe, ZC; Thapa, RK; Yong, CS | 1 |
| Barg, E; Bęben, D; Emhemmed, F; Frąszczak, J; Gębczak, K; Moreira, H; Muller, CD; Nowak, P; Radajewska, A; Siwiela, O; Szyjka, A | 1 |
2 other study(ies) available for celastrol and irinotecan
| Article | Year |
|---|---|
Folate receptor-mediated celastrol and irinotecan combination delivery using liposomes for effective chemotherapy.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Cycle; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Carriers; Drug Screening Assays, Antitumor; Folate Receptors, GPI-Anchored; Humans; Irinotecan; Liposomes; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes; Tumor Cells, Cultured | 2018 |
Combination of Irinotecan and Melatonin with the Natural Compounds Wogonin and Celastrol for Colon Cancer Treatment.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Humans; Irinotecan; Melatonin | 2023 |