Page last updated: 2024-09-03

celastrol and etoposide

celastrol has been researched along with etoposide in 2 studies

Compound Research Comparison

Studies (celastrol)	Trials (celastrol)	Recent Studies (post-2010) (celastrol)	Studies (etoposide)	Trials (etoposide)	Recent Studies (post-2010) (etoposide)
885	1	741	18,306	3,693	4,900

Protein Interaction Comparison

Protein	Taxonomy	etoposide (IC50)
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	Homo sapiens (human)	1.153
nuclear receptor coactivator 3 isoform a	Homo sapiens (human)	1.4284
Polyunsaturated fatty acid lipoxygenase ALOX15	Oryctolagus cuniculus (rabbit)	3.187
Caspase-3	Homo sapiens (human)	1
DNA topoisomerase 2-beta	Homo sapiens (human)	0.4299
Solute carrier organic anion transporter family member 1B3	Homo sapiens (human)	4.18

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P	1
Nagase, M; Oto, J; Sakato, N; Sugiyama, S; Takaishi, Y; Yube, K	1

Other Studies

2 other study(ies) available for celastrol and etoposide

Article	Year
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22 Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship	2012
Apoptosis induction in HL-60 cells and inhibition of topoisomerase II by triterpene celastrol. Bioscience, biotechnology, and biochemistry, 2003, Volume: 67, Issue:9 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Flow Cytometry; HL-60 Cells; Humans; Inhibitory Concentration 50; Molecular Structure; Pentacyclic Triterpenes; Time Factors; Topoisomerase II Inhibitors; Triterpenes	2003

Article

Year

Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012

Apoptosis induction in HL-60 cells and inhibition of topoisomerase II by triterpene celastrol.

Bioscience, biotechnology, and biochemistry, 2003, Volume: 67, Issue:9

Topics: Antineoplastic Agents, Phytogenic; Apoptosis; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Flow Cytometry; HL-60 Cells; Humans; Inhibitory Concentration 50; Molecular Structure; Pentacyclic Triterpenes; Time Factors; Topoisomerase II Inhibitors; Triterpenes

2003