Page last updated: 2024-09-03

celastrol and etoposide

celastrol has been researched along with etoposide in 2 studies

Compound Research Comparison

Studies
(celastrol)
Trials
(celastrol)
Recent Studies (post-2010)
(celastrol)
Studies
(etoposide)
Trials
(etoposide)
Recent Studies (post-2010) (etoposide)
885174118,3063,6934,900

Protein Interaction Comparison

ProteinTaxonomycelastrol (IC50)etoposide (IC50)
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]Homo sapiens (human)1.153
nuclear receptor coactivator 3 isoform aHomo sapiens (human)1.4284
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)3.187
Caspase-3Homo sapiens (human)1
DNA topoisomerase 2-betaHomo sapiens (human)0.4299
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)4.18

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Nagase, M; Oto, J; Sakato, N; Sugiyama, S; Takaishi, Y; Yube, K1

Other Studies

2 other study(ies) available for celastrol and etoposide

ArticleYear
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Apoptosis induction in HL-60 cells and inhibition of topoisomerase II by triterpene celastrol.
    Bioscience, biotechnology, and biochemistry, 2003, Volume: 67, Issue:9

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Flow Cytometry; HL-60 Cells; Humans; Inhibitory Concentration 50; Molecular Structure; Pentacyclic Triterpenes; Time Factors; Topoisomerase II Inhibitors; Triterpenes

2003