Compounds > celastrol
Page last updated: 2024-09-03

celastrol and ellagic acid

celastrol has been researched along with ellagic acid in 2 studies

Compound Research Comparison

Studies
(celastrol)		Trials
(celastrol)		Recent Studies (post-2010)
(celastrol)		Studies
(ellagic acid)		Trials
(ellagic acid)		Recent Studies (post-2010) (ellagic acid)
88517411,59125959

Protein Interaction Comparison

ProteinTaxonomycelastrol (IC50)ellagic acid (IC50)
Mcl-1Homo sapiens (human)27.285
acetyl-CoA acetyltransferase/HMG-CoA reductaseEnterococcus faecalis1265.39
heat shock 70kDa protein 1AHomo sapiens (human)0.76
mothers against decapentaplegic homolog 3 isoform 1Homo sapiens (human)0.142
heat shock cognate 71 kDa protein isoform 1Homo sapiens (human)99.2
VifHuman immunodeficiency virus 10.45
TatHuman immunodeficiency virus 11.669
DNA dC->dU-editing enzyme APOBEC-3G isoform 1Homo sapiens (human)0.45
dual specificity protein phosphatase 6Rattus norvegicus (Norway rat)39.5
heat shock cognate 71 kDa protein isoform 2Homo sapiens (human)99.2
Serine/threonine-protein kinase PLK4Homo sapiens (human)2.97
Inhibitor of nuclear factor kappa-B kinase subunit betaHomo sapiens (human)1.98
Aurora kinase AHomo sapiens (human)2.48
NUAK family SNF1-like kinase 1Homo sapiens (human)0.51
cAMP-dependent protein kinase catalytic subunit alphaBos taurus (cattle)0.6
Epidermal growth factor receptorHomo sapiens (human)0.69
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)3.54
Insulin receptorHomo sapiens (human)0.34
Insulin-like growth factor 1 receptorHomo sapiens (human)0.25
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)0.57
Muscarinic acetylcholine receptor M3Rattus norvegicus (Norway rat)0.57
Muscarinic acetylcholine receptor M4Rattus norvegicus (Norway rat)0.57
Hepatocyte growth factor receptorHomo sapiens (human)0.58
Muscarinic acetylcholine receptor M5Rattus norvegicus (Norway rat)0.57
Platelet-derived growth factor receptor betaHomo sapiens (human)1.3
Cytochrome P450 2D6Homo sapiens (human)4.77
Muscarinic acetylcholine receptor M2Rattus norvegicus (Norway rat)0.57
Cyclin-dependent kinase 4Homo sapiens (human)1.09
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)0.4667
Macrophage migration inhibitory factorHomo sapiens (human)4.77
Serine/threonine-protein kinase B-rafHomo sapiens (human)1.76
Aldo-keto reductase family 1 member B1Homo sapiens (human)0.2
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)2.05
Casein kinase II subunit alpha Rattus norvegicus (Norway rat)0.04
Casein kinase II subunit alpha'Homo sapiens (human)0.04
Cyclin-A2Homo sapiens (human)3.39
5'-nucleotidaseHomo sapiens (human)1.85
cAMP-dependent protein kinase catalytic subunit gammaHomo sapiens (human)2.05
cAMP-dependent protein kinase catalytic subunit betaHomo sapiens (human)2.05
G1/S-specific cyclin-D1Homo sapiens (human)1.09
Cyclin-dependent kinase 2Homo sapiens (human)3.39
RAC-alpha serine/threonine-protein kinaseHomo sapiens (human)3.34
Vascular endothelial growth factor receptor 3Homo sapiens (human)1.54
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.79
Mitogen-activated protein kinase kinase kinase 8Homo sapiens (human)2.37
Glycogen synthase kinase-3 betaHomo sapiens (human)7.5
Squalene monooxygenase Rattus norvegicus (Norway rat)2
Serine/threonine-protein kinase PLK1Homo sapiens (human)3.34
Ephrin type-B receptor 4Homo sapiens (human)1.83
Ectonucleoside triphosphate diphosphohydrolase 1Mus musculus (house mouse)0.5
Beta-secretase 1Homo sapiens (human)3.9
Casein kinase II subunit betaHomo sapiens (human)0.04
Casein kinase II subunit betaRattus norvegicus (Norway rat)0.04
Casein kinase II subunit alphaHomo sapiens (human)0.04
Cyclin-A1Homo sapiens (human)3.39
Angiopoietin-1 receptorHomo sapiens (human)0.26
Focal adhesion kinase 1Homo sapiens (human)3.11
Tyrosine-protein kinase Lyn Rattus norvegicus (Norway rat)7.5
Polypeptide N-acetylgalactosaminyltransferase 2Homo sapiens (human)1.72
ELAV-like protein 3Homo sapiens (human)0.6
Solute carrier family 22 member 6Homo sapiens (human)0.27
5'-nucleotidaseMus musculus (house mouse)0.04
Tyrosine-protein kinase FgrRattus norvegicus (Norway rat)3.5
Integrase Human immunodeficiency virus 15.1
Aurora kinase BHomo sapiens (human)2.5
Translin-associated protein XHomo sapiens (human)3.5
G-protein coupled receptor 35Homo sapiens (human)0.1
DNA polymerase iotaHomo sapiens (human)0.062
DNA polymerase etaHomo sapiens (human)0.062
Cysteine protease ATG4BHomo sapiens (human)4.25
M17 leucyl aminopeptidasePlasmodium falciparum 3D7138.08
likely tRNA 2'-phosphotransferaseCandida albicans SC53140.2913

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Duan, J; Huang, WD; Wang, GZ; Zhan, JC; Zhao, XC; Zhou, GB1

Other Studies

2 other study(ies) available for celastrol and ellagic acid

ArticleYear
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
The red wine component ellagic acid induces autophagy and exhibits anti-lung cancer activity in vitro and in vivo.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Autoantigens; Autophagy; Cell Proliferation; Ellagic Acid; Female; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Membrane Proteins; Mice, Inbred BALB C; Pentacyclic Triterpenes; Polyphenols; Triterpenes; Wine; Xenograft Model Antitumor Assays

2019