celastrol has been researched along with dinoprostone in 6 studies
| Studies (celastrol) | Trials (celastrol) | Recent Studies (post-2010) (celastrol) | Studies (dinoprostone) | Trials (dinoprostone) | Recent Studies (post-2010) (dinoprostone) |
|---|---|---|---|---|---|
| 885 | 1 | 741 | 29,105 | 1,346 | 6,357 |
| Protein | Taxonomy | celastrol (IC50) | dinoprostone (IC50) |
|---|---|---|---|
| Prostaglandin E2 receptor EP1 subtype | Homo sapiens (human) | 0.0155 | |
| Prostaglandin E2 receptor EP4 subtype | Homo sapiens (human) | 0.0031 | |
| Prostaglandin E2 receptor EP4 subtype | Rattus norvegicus (Norway rat) | 0.0021 | |
| Prostaglandin E2 receptor EP3 subtype | Homo sapiens (human) | 0.002 | |
| Prostaglandin E2 receptor EP2 subtype | Homo sapiens (human) | 0.0087 | |
| Prostacyclin receptor | Homo sapiens (human) | 0.26 | |
| Prostaglandin E2 receptor EP2 subtype | Rattus norvegicus (Norway rat) | 0.0052 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Cai, WZ; Cheng, ZH; Miao, HH; Pan, DJ; Xu, WM; Zhang, LX | 1 |
| Chen, WP; Cheng, Y; Ding, QH; Wang, XH; Zhong, HM | 1 |
| Kim, HJ; Kim, JK; Park, GM | 1 |
| Li, YK; Yang, XW; Yuan, SG; Zhang, P; Zou, YC | 1 |
| Ge, F; He, Q; Li, H; Wu, C; Xu, R; Yuan, Y; Zhang, Y | 1 |
6 other study(ies) available for celastrol and dinoprostone
| Article | Year |
|---|---|
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
[Inhibitory effect of tripterine on activities of IL-1, IL-2 and release of PGE2].
Topics: Animals; Dinoprostone; Dose-Response Relationship, Drug; Female; Immunosuppressive Agents; Interleukin-1; Interleukin-2; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pentacyclic Triterpenes; Peritoneal Cavity; Rabbits; Rats; Rats, Inbred Strains; Spleen; Synovial Membrane; Triterpenes | 1991 |
Celastrol, an inhibitor of heat shock protein 90β potently suppresses the expression of matrix metalloproteinases, inducible nitric oxide synthase and cyclooxygenase-2 in primary human osteoarthritic chondrocytes.
Topics: Anti-Inflammatory Agents; Cells, Cultured; Chondrocytes; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; HSP90 Heat-Shock Proteins; Humans; Interleukin-1beta; Matrix Metalloproteinases; Nitric Oxide Synthase Type II; Osteoarthritis; Pentacyclic Triterpenes; Triterpenes | 2013 |
Anti-inflammatory effect of pristimerin on lipopolysaccharide-induced inflammatory responses in murine macrophages.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cell Survival; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Inflammation Mediators; Interleukin-6; Lipopolysaccharides; Macrophages; MAP Kinase Signaling System; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Pentacyclic Triterpenes; Triterpenes; Tumor Necrosis Factor-alpha | 2013 |
Celastrol inhibits prostaglandin E2-induced proliferation and osteogenic differentiation of fibroblasts isolated from ankylosing spondylitis hip tissues in vitro.
Topics: Adult; Cell Differentiation; Cell Proliferation; Dinoprostone; Dose-Response Relationship, Drug; Female; Fibroblasts; Hip Joint; Humans; Male; Osteogenesis; Pentacyclic Triterpenes; Spondylitis, Ankylosing; Structure-Activity Relationship; Triterpenes | 2016 |
Celastrol inhibits IL-1β-induced inflammation in orbital fibroblasts through the suppression of NF-κB activity.
Topics: Anti-Inflammatory Agents; Apoptosis; Cell Survival; Cyclooxygenase 2; Dinoprostone; Enzyme Activation; Female; Fibroblasts; Gene Expression; Graves Disease; Humans; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1beta; Interleukin-6; Interleukin-8; Male; NF-kappa B; Pentacyclic Triterpenes; Signal Transduction; Triterpenes | 2016 |