celastrol has been researched along with cycloheximide in 3 studies
| Studies (celastrol) | Trials (celastrol) | Recent Studies (post-2010) (celastrol) | Studies (cycloheximide) | Trials (cycloheximide) | Recent Studies (post-2010) (cycloheximide) |
|---|---|---|---|---|---|
| 885 | 1 | 741 | 19,109 | 6 | 861 |
| Protein | Taxonomy | celastrol (IC50) | cycloheximide (IC50) |
|---|---|---|---|
| COUP transcription factor 2 isoform a | Homo sapiens (human) | 1.315 | |
| Glucose transporter | Leishmania mexicana | 0.242 | |
| Hexose transporter 1 | Plasmodium falciparum (malaria parasite P. falciparum) | 0.31 | |
| Solute carrier family 2, facilitated glucose transporter member 1 | Homo sapiens (human) | 0.228 | |
| Eukaryotic initiation factor 4A-I | Homo sapiens (human) | 0.139 | |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | 3.6 | |
| Hypoxia-inducible factor 1-alpha | Homo sapiens (human) | 0.036 | |
| Endothelial PAS domain-containing protein 1 | Homo sapiens (human) | 0.036 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Feng, LX; Guan, SH; Guo, DA; Jiang, BH; Liu, X; Wang, WB; Wu, WY; Yang, M; Yue, QX | 1 |
3 other study(ies) available for celastrol and cycloheximide
| Article | Year |
|---|---|
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Paraptosis accompanied by autophagy and apoptosis was induced by celastrol, a natural compound with influence on proteasome, ER stress and Hsp90.
Topics: Apoptosis; Autophagy; Cell Cycle; Cell Line, Tumor; Cycloheximide; Endoplasmic Reticulum; Enzyme Activation; Enzyme Inhibitors; HeLa Cells; HSP90 Heat-Shock Proteins; Humans; MAP Kinase Signaling System; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinases; Pentacyclic Triterpenes; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; Stress, Physiological; Triterpenes; Vacuoles | 2012 |