Page last updated: 2024-09-03

celastrol and cryptotanshinone

celastrol has been researched along with cryptotanshinone in 3 studies

Compound Research Comparison

Studies
(celastrol)
Trials
(celastrol)
Recent Studies (post-2010)
(celastrol)
Studies
(cryptotanshinone)
Trials
(cryptotanshinone)
Recent Studies (post-2010) (cryptotanshinone)
88517413700268

Protein Interaction Comparison

ProteinTaxonomycelastrol (IC50)cryptotanshinone (IC50)
Chain A, RNA-directed RNA polymerase NS5Dengue virus 2 16681-PDK5390.06
Lysine-specific histone demethylase 1AHomo sapiens (human)9.02
Replicase polyprotein 1aSevere acute respiratory syndrome-related coronavirus0.8
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 23.722
Indoleamine 2,3-dioxygenase 1Homo sapiens (human)10
Signal transducer and activator of transcription 3Homo sapiens (human)4.6
Tryptophan 2,3-dioxygenaseHomo sapiens (human)9.8
Hypoxia-inducible factor 1-alphaHomo sapiens (human)1.47
Endothelial PAS domain-containing protein 1Homo sapiens (human)1.47

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Chen, J; Gao, K; Huang, F; Tepe, JJ; Wang, R; Wei, GW1
Song, Y; Wang, S; Yang, X; Yu, B; Zhao, M1

Reviews

1 review(s) available for celastrol and cryptotanshinone

ArticleYear
Strategies Targeting Protein Tyrosine Phosphatase SHP2 for Cancer Therapy.
    Journal of medicinal chemistry, 2022, 02-24, Volume: 65, Issue:4

    Topics: Animals; Antineoplastic Agents; Drug Design; Drug Discovery; Enzyme Inhibitors; Humans; Neoplasms; Protein Tyrosine Phosphatase, Non-Receptor Type 11

2022

Other Studies

2 other study(ies) available for celastrol and cryptotanshinone

ArticleYear
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Perspectives on SARS-CoV-2 Main Protease Inhibitors.
    Journal of medicinal chemistry, 2021, 12-09, Volume: 64, Issue:23

    Topics: Antiviral Agents; Coronavirus 3C Proteases; Humans; Protease Inhibitors

2021