Page last updated: 2024-09-03

celastrol and catechin

celastrol has been researched along with catechin in 5 studies

Compound Research Comparison

Studies
(celastrol)
Trials
(celastrol)
Recent Studies (post-2010)
(celastrol)
Studies
(catechin)
Trials
(catechin)
Recent Studies (post-2010) (catechin)
885174142020
885174111,5444776,612
8851741701

Protein Interaction Comparison

ProteinTaxonomycelastrol (IC50)catechin (IC50)
Arginase Leishmania amazonensis1.7
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproproteinHomo sapiens (human)37.1
intestinal alkaline phosphatase precursorMus musculus (house mouse)15.5
large T antigenBetapolyomavirus macacae11.41

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Chen, J; Gao, K; Huang, F; Tepe, JJ; Wang, R; Wei, GW1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Bai, JP; Fang, X; Shi, QX; Shi, YL1
Chan, TH; Davenport, A; Dou, QP; Frezza, M; Ge, Y; Huo, C; Shen, M1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1

Other Studies

5 other study(ies) available for celastrol and catechin

ArticleYear
Perspectives on SARS-CoV-2 Main Protease Inhibitors.
    Journal of medicinal chemistry, 2021, 12-09, Volume: 64, Issue:23

    Topics: Antiviral Agents; Coronavirus 3C Proteases; Humans; Protease Inhibitors

2021
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Effects of demethylzeylasteral and celastrol on spermatogenic cell Ca2+ channels and progesterone-induced sperm acrosome reaction.
    European journal of pharmacology, 2003, Mar-07, Volume: 464, Issue:1

    Topics: Acrosome Reaction; Amiloride; Animals; Calcium Channels; Catechin; Contraceptive Agents, Male; Dose-Response Relationship, Drug; Gossypol; Male; Membrane Potentials; Mice; Mice, Inbred ICR; Pentacyclic Triterpenes; Progesterone; Spermatozoa; Time Factors; Triterpenes

2003
Celastrol and an EGCG pro-drug exhibit potent chemosensitizing activity in human leukemia cells.
    International journal of molecular medicine, 2010, Volume: 25, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cytarabine; Daunorubicin; Fusion Proteins, bcr-abl; Humans; Leukemia; Molecular Structure; Pentacyclic Triterpenes; Plant Extracts; Prodrugs; Triterpenes

2010
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012