celastrol has been researched along with acetylcysteine in 6 studies
| Studies (celastrol) | Trials (celastrol) | Recent Studies (post-2010) (celastrol) | Studies (acetylcysteine) | Trials (acetylcysteine) | Recent Studies (post-2010) (acetylcysteine) |
|---|---|---|---|---|---|
| 885 | 1 | 741 | 14,580 | 1,046 | 5,960 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Chen, D; Dou, QP; Landis-Piwowar, KR; Milacic, V; Yang, H | 1 |
| Jantas, D; Konieczny, J; Kuśmierczyk, J; Lasoń, W; Lenda, T; Lorenc-Koci, E; Roman, A | 1 |
| Czarnecka, A; Domin, H; Jantas, D; Konieczny, J; Kuter, K; Lasoń, W; Lenda, T; Lorenc-Koci, E; Śmiałowska, M | 1 |
| Kim, ND; Lee, BH; Lee, JY | 1 |
| Nazim, UM; Park, SY; Yin, H | 1 |
1 review(s) available for celastrol and acetylcysteine
| Article | Year |
|---|---|
Natural compounds with proteasome inhibitory activity for cancer prevention and treatment.
Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Boronic Acids; Bortezomib; Clinical Trials as Topic; Curcumin; Humans; Neoplasms; Pentacyclic Triterpenes; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Triterpenes; Ubiquitin | 2008 |
5 other study(ies) available for celastrol and acetylcysteine
| Article | Year |
|---|---|
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
The extent of neurodegeneration and neuroprotection in two chemical in vitro models related to Parkinson's disease is critically dependent on cell culture conditions.
Topics: Acetylcysteine; Cell Death; Cell Differentiation; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Drug Interactions; Humans; Nerve Degeneration; Neuroprotective Agents; Parkinson Disease; Pentacyclic Triterpenes; Rotenone; Time Factors; Tretinoin; Triterpenes | 2013 |
Lack of neuroprotective effect of celastrol under conditions of proteasome inhibition by lactacystin in in vitro and in vivo studies: implications for Parkinson's disease.
Topics: Acetylcysteine; Animals; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Dopamine; Humans; Male; Mice; Neuroblastoma; Neurons; Neuroprotective Agents; Parkinson Disease; Pentacyclic Triterpenes; Proteasome Inhibitors; Rats; Rats, Wistar; Substantia Nigra; Triterpenes | 2014 |
Celastrol blocks binding of lipopolysaccharides to a Toll-like receptor4/myeloid differentiation factor2 complex in a thiol-dependent manner.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Cytokines; Dithiothreitol; Enzyme-Linked Immunosorbent Assay; Lipopolysaccharides; Lymphocyte Antigen 96; Macrophages; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; Pentacyclic Triterpenes; Polymerase Chain Reaction; Sulfhydryl Compounds; Toll-Like Receptor 4; Tripterygium; Triterpenes | 2015 |
Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species.
Topics: A549 Cells; Acetylcysteine; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Caspase 8; Cell Line, Tumor; Chloroquine; Drug Combinations; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Membrane Potential, Mitochondrial; Microtubule-Associated Proteins; Mitochondria; Pentacyclic Triterpenes; Reactive Oxygen Species; Sequestosome-1 Protein; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Triterpenes | 2019 |