Page last updated: 2024-09-03

celastrol and Dihydrotanshinone I

celastrol has been researched along with Dihydrotanshinone I in 4 studies

Compound Research Comparison

Studies
(celastrol)
Trials
(celastrol)
Recent Studies (post-2010)
(celastrol)
Studies
(Dihydrotanshinone I)
Trials
(Dihydrotanshinone I)
Recent Studies (post-2010) (Dihydrotanshinone I)
885174188074

Protein Interaction Comparison

ProteinTaxonomycelastrol (IC50)Dihydrotanshinone I (IC50)
Replicase polyprotein 1aSevere acute respiratory syndrome-related coronavirus3.05
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 20.59
AcetylcholinesteraseHomo sapiens (human)1
Tyrosine-protein phosphatase non-receptor type 6Homo sapiens (human)3.67
Tyrosine-protein phosphatase non-receptor type 11Homo sapiens (human)3.94
ELAV-like protein 1Homo sapiens (human)0.1085
Hypoxia-inducible factor 1-alphaHomo sapiens (human)2.17
Endothelial PAS domain-containing protein 1Homo sapiens (human)2.17

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Abdeen, S; Chapman, E; Chitre, S; Hoang, QQ; Johnson, SM; Park, Y; Ray, AM; Salim, N; Sivinski, J; Stevens, M; Washburn, A1
Chen, J; Gao, K; Huang, F; Tepe, JJ; Wang, R; Wei, GW1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1

Other Studies

4 other study(ies) available for celastrol and Dihydrotanshinone I

ArticleYear
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules.
    Bioorganic & medicinal chemistry letters, 2019, 05-01, Volume: 29, Issue:9

    Topics: Biological Products; Chaperonin 10; Chaperonin 60; Escherichia coli; Humans; Inhibitory Concentration 50; Protein Folding; Rafoxanide; Salicylanilides; Suramin

2019
Perspectives on SARS-CoV-2 Main Protease Inhibitors.
    Journal of medicinal chemistry, 2021, 12-09, Volume: 64, Issue:23

    Topics: Antiviral Agents; Coronavirus 3C Proteases; Humans; Protease Inhibitors

2021
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023