ceftobiprole has been researched along with endolysin* in 1 studies
1 other study(ies) available for ceftobiprole and endolysin
Article | Year |
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The Recombinant Bacteriophage Endolysin HY-133 Exhibits In Vitro Activity against Different African Clonal Lineages of the Staphylococcus aureus Complex, Including Staphylococcus schweitzeri.
HY-133 is a recombinant bacteriophage endolysin with bactericidal activity againstStaphylococcus aureus Here, HY-133 showedin vitroactivity against major African methicillin-susceptible and methicillin-resistantS. aureuslineages and ceftaroline/ceftobiprole- and borderline oxacillin-resistant isolates. HY-133 was also active againstStaphylococcus schweitzeri, a recently described species of theS. aureuscomplex. The activity of HY-133 on the tested isolates (MIC50, 0.25 μg/ml; MIC90, 0.5 μg/ml; range, 0.125 to 0.5 μg/ml) was independent of the species and strain background or antibiotic resistance. Topics: Africa; Anti-Bacterial Agents; beta-Lactam Resistance; Ceftaroline; Cephalosporins; Endopeptidases; Humans; Methicillin Resistance; Microbial Sensitivity Tests; Recombinant Proteins; Staphylococcal Infections; Staphylococcus; Staphylococcus aureus; Staphylococcus Phages | 2016 |