cefixime and tetracycline

cefixime has been researched along with tetracycline in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (2.78)	18.2507
2000's	8 (22.22)	29.6817
2010's	16 (44.44)	24.3611
2020's	11 (30.56)	2.80

Authors

Authors	Studies
Flanagan, C; Nash, DR; Steele, LC; Wallace, RJ	1
Bachor, J; Dinari, G; Fishman, M; Gal, E; Geler, A; Niv, Y; Passaro, DJ; Samra, Z; Shmuely, H; Yahav, J	1
Furuya, R; Iyoda, T; Kanayama, A; Kobayashi, I; Matsuzaki, K; Onoye, Y; Saika, T; Tanaka, M; Tatewaki, M	1
Alexander, S; Anderson, J; Chisholm, SA; Desouza-Thomas, L; Ison, CA; Lowndes, CM; Maclure-Webster, E; Nichols, T	1
Adelson, ME; Balashov, S; Gygax, SE; Mordechai, E	1
Dillon, JA; Horsman, GB; Levett, PN; Thakur, SD	1
Endimiani, A; Furrer, H; Guilarte, YN; Hauser, C; Hirzberger, L; Lupo, A; Selvini, S; Tinguely, R	1
Antonetti, R; Bonanno, C; Busetti, M; Carannante, A; Cava, MC; Cusini, M; D'Antuono, A; Dal Conte, I; Gaino, M; Ghisetti, V; Giraldi, C; Impara, G; Latino, MA; Matteelli, A; Mencacci, A; Prignano, G; Renna, G; Stefanelli, P; Vocale, C	1
Althaus, CL; Foerster, S; Hathaway, LJ; Low, N; Unemo, M	1
Brunner, A; Jeney, C; Karpati, S; Marschalko, M; Nemes-Nikodem, E; Ostorhazi, E; Szabo, D	1
Chen, SC; Chen, XS; Dai, XQ; Han, Y; Yin, Y; Yu, RX; Zhang, GY; Zheng, BJ	1
Cole, K; Cole, MJ; Crook, DW; De Silva, D; Demczuk, W; Eyre, DW; Grad, YH; Martin, I; Mulvey, MR; Paul, J; Peters, J; Peto, TEA; Walker, AS	1
Indriatmi, W; Nilasari, H; Prayogo, RL; Suseno, LS	1
Dobre-Buonya, O; Kilic, A; McNeil, CJ; Palavecino, EL; Schmerer, MW; Toler, C	1
Hamill, MM; Kajumbula, H; Kakooza, F; Kyambadde, P; Lamorde, M; Manabe, YC; Mande, E; Mbabazi, O; Mugasha, R; Musinguzi, P; Wagner, J; Walwema, R; Workneh, M; Zenilman, J	1
Bima, APH; Khumairoh, I; Kusuma, SAF; Ramdhani, D; Sediana, D	1
Bonongwe, N; Chen, JS; Chikaonda, T; Cohen, MS; Golparian, D; Hobbs, MM; Hoffman, IF; Jere, E; Kamtambe, B; Krysiak, R; Massa, C; Mathiya, E; Matoga, M; Ndalama, B; Unemo, M	1
Jenjaroenpun, P; Nitayanon, P; Nokchan, N; Tribuddharat, C; Wongsurawat, T	1
Kiamos, A; Sands, M; Torrente, N; Verdecia, J	1
Debelo, M; Mohammed, N; Tiruneh, A; Tolosa, T	1
Akool, MA; Al-Nafak, RT; Al-Turaihi, TSA; Hadi, ZJ; Mubark, HA	1
Chen, Q; Chen, Y; Huang, X; Ji, X; Lin, Z; Suo, B; Wu, B; Zheng, X; Zhou, X	1
Dingle, TC; Ferrato, C; Gratrix, J; Ma, A; Martin, I; Smyczek, P	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Arakawa, Y; Kimura, K; Nagano, N; Nagano, Y; Tamai, K; Yanagisawa, H	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chatre, P; Delmas, JM; Faure, S; Laurentie, M; Perrin-Guyomard, A	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Allen, VG; Farrell, DJ; Lo, S; Low, DE; Melano, RG; Perusini, SJ; Rebbapragada, A; Tan, J; Tijet, N; Towns, L	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1

Reviews

1 review(s) available for cefixime and tetracycline

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

35 other study(ies) available for cefixime and tetracycline

Article	Year
Comparison of the activity of cefixime and activities of other oral antibiotics against adult clinical isolates of Moraxella (Branhamella) catarrhalis containing BRO-1 and BRO-2 and Haemophilus influenzae. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:1 Topics: Administration, Oral; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactamases; Cefixime; Cefotaxime; Cephalosporins; Clavulanic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erythromycin; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Moraxella catarrhalis; Tetracycline	1991
Resistance of Helicobacter pylori isolated in Israel to metronidazole, clarithromycin, tetracycline, amoxicillin and cefixime. The Journal of antimicrobial chemotherapy, 2002, Volume: 49, Issue:6 Topics: Amoxicillin; Cefixime; Chi-Square Distribution; Clarithromycin; Confidence Intervals; Drug Resistance, Multiple, Bacterial; Female; Helicobacter Infections; Helicobacter pylori; Humans; Israel; Male; Metronidazole; Microbial Sensitivity Tests; Middle Aged; Tetracycline	2002
Antimicrobial resistance in clinical isolates of Neisseria subflava from the oral cavities of a Japanese population. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2007, Volume: 13, Issue:5 Topics: Anti-Bacterial Agents; Cefixime; Ceftriaxone; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Female; Gram-Negative Bacterial Infections; Humans; Japan; Male; Microbial Sensitivity Tests; Mouth; Neisseria; Penicillins; Tetracycline	2007
Emergence of a Neisseria gonorrhoeae clone showing decreased susceptibility to cefixime in England and Wales. The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:11 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Cefixime; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; England; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Molecular Epidemiology; Molecular Typing; Neisseria gonorrhoeae; Penicillins; Sexual Behavior; Tetracycline; Wales	2011
Multiplex bead suspension array for screening Neisseria gonorrhoeae antibiotic resistance genetic determinants in noncultured clinical samples. The Journal of molecular diagnostics : JMD, 2013, Volume: 15, Issue:1 Topics: Alleles; Anti-Infective Agents; Azithromycin; Cefixime; Cephalosporins; Chromosomes, Bacterial; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Bacterial; Gene Expression Profiling; High-Throughput Nucleotide Sequencing; Humans; Microbial Sensitivity Tests; Mutation; Neisseria gonorrhoeae; Penicillins; Plasmids; Reproducibility of Results; Sensitivity and Specificity; Sequence Analysis, DNA; Spectinomycin; Tetracycline	2013
Molecular epidemiology of Neisseria gonorrhoeae isolates from Saskatchewan, Canada: utility of NG-MAST in predicting antimicrobial susceptibility regionally. Sexually transmitted infections, 2014, Volume: 90, Issue:4 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Azithromycin; Bacterial Typing Techniques; Cefixime; Ceftriaxone; Child; Child, Preschool; Ciprofloxacin; DNA, Bacterial; Female; Gonorrhea; Humans; Infant; Male; Microbial Sensitivity Tests; Middle Aged; Molecular Typing; Neisseria gonorrhoeae; Penicillins; Saskatchewan; Sequence Analysis, DNA; Spectinomycin; Tetracycline; Young Adult	2014
Characterization of Neisseria gonorrhoeae isolates detected in Switzerland (1998-2012): emergence of multidrug-resistant clones less susceptible to cephalosporins. BMC infectious diseases, 2014, Feb-25, Volume: 14 Topics: Adolescent; Adult; Anti-Bacterial Agents; Azithromycin; Cefixime; Ceftriaxone; Cephalosporins; Child; Child, Preschool; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Female; Gonorrhea; Humans; Infant; Infant, Newborn; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillins; Phenotype; Switzerland; Tetracycline; Young Adult	2014
Changing antimicrobial resistance profiles among Neisseria gonorrhoeae isolates in Italy, 2003 to 2012. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:10 Topics: Anti-Bacterial Agents; Azithromycin; Cefixime; Ciprofloxacin; Humans; Italy; Male; Neisseria gonorrhoeae; Penicillinase; Penicillins; Retrospective Studies; Tetracycline	2014
Time-kill curve analysis and pharmacodynamic modelling for in vitro evaluation of antimicrobials against Neisseria gonorrhoeae. BMC microbiology, 2016, 09-17, Volume: 16 Topics: Anti-Bacterial Agents; Cefixime; Ceftriaxone; Cell Count; Cell Survival; Chloramphenicol; Ciprofloxacin; Gentamicins; Growth Charts; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Models, Theoretical; Neisseria gonorrhoeae; Penicillin G; Spectinomycin; Tetracycline; Time Factors	2016
Emerging azithromycin-resistance among the Neisseria gonorrhoeae strains isolated in Hungary. Annals of clinical microbiology and antimicrobials, 2016, Sep-20, Volume: 15, Issue:1 Topics: Adult; Alleles; Anti-Bacterial Agents; Azithromycin; Bacterial Typing Techniques; Cefixime; Ceftriaxone; Ciprofloxacin; Drug Resistance, Bacterial; Female; Gene Expression; Gonorrhea; Humans; Hungary; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Phylogeny; Porins; Prevalence; Spectinomycin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetracycline; Transferrin-Binding Protein B	2016
Antimicrobial Susceptibility Evaluation and Multiple-Locus Variable Number Tandem Repeat Analysis of Neisseria gonorrhoeae Isolates in China in 2012. Sexually transmitted diseases, 2017, Volume: 44, Issue:4 Topics: Adult; Anti-Bacterial Agents; Cefixime; Ceftriaxone; Cervix Uteri; Chi-Square Distribution; China; Ciprofloxacin; Drug Resistance, Bacterial; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Minisatellite Repeats; Neisseria gonorrhoeae; Penicillins; Prevalence; Spectinomycin; Tetracycline; Urethra; Young Adult	2017
WGS to predict antibiotic MICs for Neisseria gonorrhoeae. The Journal of antimicrobial chemotherapy, 2017, 07-01, Volume: 72, Issue:7 Topics: Anti-Bacterial Agents; Azithromycin; Canada; Cefixime; Ciprofloxacin; Drug Resistance, Bacterial; England; Genome, Bacterial; Gonorrhea; High-Throughput Nucleotide Sequencing; Humans; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillin G; Tetracycline; United States; Whole Genome Sequencing	2017
Antimicrobial resistance of Neisseria gonorrhoeae in Jakarta, Indonesia: a cross-sectional study. Sexual health, 2020, Volume: 17, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefixime; Ceftriaxone; Cross-Sectional Studies; Drug Resistance, Bacterial; Female; Gonorrhea; Humans; Indonesia; Levofloxacin; Male; Middle Aged; Neisseria gonorrhoeae; Penicillins; Tetracycline	2020
First Case of High-Level Azithromycin-Resistant Neisseria gonorrhoeae in North Carolina. Sexually transmitted diseases, 2020, Volume: 47, Issue:5 Topics: Adult; Anti-Bacterial Agents; Azithromycin; Cefixime; Ceftriaxone; Drug Resistance, Bacterial; Gonorrhea; HIV Seronegativity; Homosexuality, Male; Humans; Male; Microbial Sensitivity Tests; Multilocus Sequence Typing; Neisseria gonorrhoeae; North Carolina; Penicillins; Pharynx; Tetracycline; Whole Genome Sequencing	2020
Antimicrobial Resistance of Neisseria Gonorrhoeae in a Newly Implemented Surveillance Program in Uganda: Surveillance Report. JMIR public health and surveillance, 2020, 06-10, Volume: 6, Issue:2 Topics: Adult; Anti-Bacterial Agents; Cefixime; Ceftriaxone; Ciprofloxacin; Demography; Drug Resistance, Bacterial; Female; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Penicillin G; Population Surveillance; Sentinel Surveillance; Spectinomycin; Tetracycline; Uganda	2020
Comparative study of cefixime and tetracycline as an evaluation policy driven by the antibiotic resistance crisis in Indonesia. Scientific reports, 2021, 09-16, Volume: 11, Issue:1 Topics: Anti-Bacterial Agents; Bordetella; Cefixime; Corynebacterium; Disk Diffusion Antimicrobial Tests; Drug Dosage Calculations; Drug Resistance, Bacterial; Haemophilus; Humans; Respiratory Tract Infections; Staphylococcus; Streptococcus; Tetracycline	2021
Gentamicin Susceptibility in Neisseria gonorrhoeae and Treatment Outcomes for Urogenital Gonorrhea After 25 Years of Sustained Gentamicin Use in Malawi. Sexually transmitted diseases, 2022, 04-01, Volume: 49, Issue:4 Topics: Anti-Bacterial Agents; Azithromycin; Cefixime; Ceftriaxone; Ciprofloxacin; Female; Gentamicins; Gonorrhea; Humans; Malawi; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Polymorphism, Single Nucleotide; Spectinomycin; Tetracycline; Treatment Outcome	2022
Whole-genome sequence analysis of high-level penicillin-resistant strains and antimicrobial susceptibility of Neisseria gonorrhoeae clinical isolates from Thailand. PloS one, 2022, Volume: 17, Issue:7 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone; Ciprofloxacin; Gonorrhea; Humans; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillins; Sequence Analysis; Spectinomycin; Tetracycline; Thailand	2022
Right hip gonococcal septic arthritis treatment with successful transition to oral fluoroquinolone. BMJ case reports, 2022, Sep-16, Volume: 15, Issue:9 Topics: Anti-Bacterial Agents; Arthritis, Infectious; Cefixime; Ceftriaxone; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gonorrhea; Humans; Levofloxacin; Tetracycline	2022
Isolation, identification and antibiotic resistance profile of thermophilic Campylobacter species from Bovine, Knives and personnel at Jimma Town Abattoir, Ethiopia. PloS one, 2022, Volume: 17, Issue:10 Topics: Abattoirs; Agar; Ampicillin; Animals; Anti-Bacterial Agents; Campylobacter; Campylobacter Infections; Cattle; Cefixime; Ceftriaxone; Cephalothin; Chloramphenicol; Ciprofloxacin; Clindamycin; Cross-Sectional Studies; Drug Resistance, Bacterial; Drug Resistance, Microbial; Ethiopia; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Tetracycline	2022
ANTIBIOTIC RESISTANCE OF SALMONELLA TYPHI CARRIER ASSOCIATED WITH GALL BLADDER CHRONIC INFECTION IN AL-NAJAF PROVINCE. Wiadomosci lekarskie (Warsaw, Poland : 1960), 2023, Volume: 76, Issue:1 Topics: Ampicillin; Anti-Bacterial Agents; Cefepime; Cefixime; Chloramphenicol; Ciprofloxacin; Communicable Diseases; Drug Resistance, Microbial; Gallbladder Diseases; Humans; Persistent Infection; Salmonella typhi; Tetracycline	2023
Antibiotic resistance profile of PeerJ, 2023, Volume: 11 Topics: Amoxicillin; Anti-Bacterial Agents; Cefixime; Clarithromycin; Doxycycline; Drug Resistance, Bacterial; Furazolidone; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Metronidazole; Microbial Sensitivity Tests; Tetracycline	2023
Use of genome sequencing to resolve differences in gradient diffusion and agar dilution antimicrobial susceptibility testing performance of Journal of clinical microbiology, 2023, Nov-21, Volume: 61, Issue:11 Topics: Agar; Alberta; Anti-Bacterial Agents; Azithromycin; Cefixime; Ceftriaxone; Ciprofloxacin; Gonorrhea; Humans; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillins; Retrospective Studies; Tetracycline	2023
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:12 Topics: Aminoacyltransferases; Anti-Bacterial Agents; Bacterial Proteins; Female; Genetic Heterogeneity; Humans; Infant, Newborn; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillin Resistance; Penicillin-Binding Proteins; Penicillins; Phylogeny; Sequence Analysis, DNA; Streptococcus agalactiae	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Transfer of plasmid-mediated CTX-M-9 from Salmonella enterica serotype Virchow to Enterobacteriaceae in human flora-associated rats treated with cefixime. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Cefixime; Chromatography, High Pressure Liquid; Conjugation, Genetic; Culture Media; Enterobacteriaceae; Escherichia coli; Escherichia coli Proteins; Feces; Female; Humans; Intestines; Male; Mass Spectrometry; Mice; Mice, Inbred C3H; Microbial Sensitivity Tests; Plasmids; Rats; Salmonella enterica	2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Molecular analysis of antimicrobial resistance mechanisms in Neisseria gonorrhoeae isolates from Ontario, Canada. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:2 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Cefixime; Ceftriaxone; Cephalosporins; DNA, Bacterial; Drug Resistance, Bacterial; Gonorrhea; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Neisseria gonorrhoeae; Ontario; Penicillin-Binding Proteins; Polymerase Chain Reaction; Sequence Analysis, DNA	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013