cefixime and cephradine

cefixime has been researched along with cephradine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19903 (15.79)18.7374
1990's6 (31.58)18.2507
2000's7 (36.84)29.6817
2010's3 (15.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Inui, K; Saito, H; Yamamoto, M1
Hori, R; Inui, K; Katsura, T; Okano, T; Tomita, Y1
Hori, R; Inui, K; Kato, M; Maegawa, H; Okano, T; Takano, M1
Asai, H; Itoh, Y; Kawamura, S; Kobayashi, K; Matsunaga, T; Ogino, H; Onishi, S; Sakamoto, Y; Shiraishi, T; Ueda, R1
Faulkner, RD; Hiltke, MF; McAteer, JA; Silber, BM1
Hamano, S; Nakanishi, M; Tamai, I; Terasaki, T; Tsuji, A1
Verbist, L; Verhaegen, J1
Itoh, T; Shimizu, R; Sukegawa, T; Tsuda, Y1
Chen, J; He, J; Miao, X; Wu, X; Xie, Y; Xu, B; Xu, M; Yu, L; Zhang, W1
Inui, K; Mukai, M; Saito, H; Terada, T2
Carter, AL; Ganapathy, ME; Ganapathy, V; Huang, W; Iseki, K; Leibach, FH; Rajan, DP; Sugawara, M1
Brandsch, M; Luckner, P1
Biegel, A; Brandsch, M; Gebauer, S; Hartrodt, B; Neubert, K; Thondorf, I1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for cefixime and cephradine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for cefixime and cephradine

ArticleYear
[A parallel comparative double blind study of cefixime with cefroxadine in the treatment of acute lacunar tonsillitis].
    The Japanese journal of antibiotics, 1987, Volume: 40, Issue:1

    Topics: Acute Disease; Cefixime; Cefotaxime; Cephalosporins; Cephradine; Clinical Trials as Topic; Double-Blind Method; Humans; Tonsillitis

1987

Other Studies

17 other study(ies) available for cefixime and cephradine

ArticleYear
Transepithelial transport of oral cephalosporins by monolayers of intestinal epithelial cell line Caco-2: specific transport systems in apical and basolateral membranes.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:1

    Topics: Amino Acids; Anti-Infective Agents, Urinary; Biological Transport; Cefixime; Cefotaxime; Cefotiam; Cell Line; Cell Membrane; Cells, Cultured; Cephalexin; Cephradine; Epithelium; Intestinal Mucosa; Intestines

1992
Transport mechanisms of bestatin in rabbit intestinal brush-border membranes: role of H+/dipeptide cotransport system.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:2

    Topics: Adjuvants, Immunologic; Aminopeptidases; Animals; Biological Transport; Cefixime; Cefotaxime; Cephradine; Dipeptides; Hydrogen-Ion Concentration; Intestinal Mucosa; Leucine; Male; Microvilli; Rabbits

1990
H+ coupled transport of p.o. cephalosporins via dipeptide carriers in rabbit intestinal brush-border membranes: difference of transport characteristics between cefixime and cephradine.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:1

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Administration, Oral; Animals; Biological Transport; Cefixime; Cefotaxime; Cephalosporins; Cephradine; Dipeptides; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Mucosa; Male; Microvilli; Rabbits; Structure-Activity Relationship

1988
Liquid-chromatographic determination of five orally active cephalosporins--cefixime, cefaclor, cefadroxil, cephalexin, and cephradine--in human serum.
    Clinical chemistry, 1987, Volume: 33, Issue:10

    Topics: Cefaclor; Cefadroxil; Cefixime; Cefotaxime; Cephalexin; Cephalosporins; Cephradine; Chromatography, High Pressure Liquid; Humans; Reference Standards; Reference Values

1987
Intestinal brush-border transport of the oral cephalosporin antibiotic, cefdinir, mediated by dipeptide and monocarboxylic acid transport systems in rabbits.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:11

    Topics: Acetates; Animals; Biological Transport, Active; Carboxylic Acids; Cefdinir; Cefixime; Cefotaxime; Cephalosporins; Cephradine; Dipeptides; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Male; Membrane Potentials; Microvilli; Rabbits

1993
In-vitro activity of 21 beta-lactam antibiotics against penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae.
    The Journal of antimicrobial chemotherapy, 1998, Volume: 41, Issue:3

    Topics: Amoxicillin; Ampicillin; Anti-Bacterial Agents; beta-Lactams; Carbapenems; Cefaclor; Cefadroxil; Cefatrizine; Cefepime; Cefixime; Cefotaxime; Cefpirome; Cefpodoxime; Ceftazidime; Ceftibuten; Ceftizoxime; Ceftriaxone; Cefuroxime; Cephalosporins; Cephradine; Drug Resistance, Microbial; Drug Resistance, Multiple; Humans; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Piperacillin; Pneumococcal Infections; Serotyping; Species Specificity; Streptococcus pneumoniae

1998
Quantitative prediction of oral absorption of PEPT1 substrates based on in vitro uptake into Caco-2 cells.
    International journal of pharmaceutics, 2008, Apr-16, Volume: 354, Issue:1-2

    Topics: Absorption; Administration, Oral; Anti-Bacterial Agents; beta-Lactams; Biological Transport; Caco-2 Cells; Cefixime; Cefotiam; Cephradine; Dipeptides; Forecasting; Humans; Models, Biological; Peptide Transporter 1; Symporters

2008
Antimicrobial resistance and prevalence of resistance genes of obligate anaerobes isolated from periodontal abscesses.
    Journal of periodontology, 2014, Volume: 85, Issue:2

    Topics: Amoxicillin; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Proteins; Bacteriological Techniques; Bacteroidaceae Infections; beta-Lactam Resistance; beta-Lactamases; Cefixime; Cephradine; Clindamycin; Doxycycline; Drug Resistance, Bacterial; Female; Genes, Bacterial; Humans; Imipenem; Male; Methyltransferases; Metronidazole; Middle Aged; Periodontal Abscess; Prevotella; Roxithromycin; Tetracycline Resistance

2014
Characterization of stably transfected kidney epithelial cell line expressing rat H+/peptide cotransporter PEPT1: localization of PEPT1 and transport of beta-lactam antibiotics.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:3

    Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Biological Transport; Cell Line; Dose-Response Relationship, Drug; Epithelium; Hydrogen; Kidney; Peptides; Rats; Transfection

1997
Recognition of beta-lactam antibiotics by rat peptide transporters, PEPT1 and PEPT2, in LLC-PK1 cells.
    The American journal of physiology, 1997, Volume: 273, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Biological Transport; Carrier Proteins; Ceftibuten; Cephalosporins; Cyclacillin; Dipeptides; Hydrogen-Ion Concentration; Kidney; Kinetics; LLC-PK1 Cells; Peptide Transporter 1; Rats; Recombinant Proteins; Structure-Activity Relationship; Symporters; Transfection

1997
beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter.
    The Journal of biological chemistry, 2000, Jan-21, Volume: 275, Issue:3

    Topics: Acetylcarnitine; Animals; Anti-Bacterial Agents; Carnitine; Carrier Proteins; Cefadroxil; Cefepime; Cephaloridine; Cephalosporins; Dose-Response Relationship, Drug; HeLa Cells; Humans; Kinetics; Membrane Proteins; Nitrogen; Organic Cation Transport Proteins; Rats; Sodium; Solute Carrier Family 22 Member 5; Tumor Cells, Cultured

2000
Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2005, Volume: 59, Issue:1

    Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Binding Sites; Caco-2 Cells; Dose-Response Relationship, Drug; Humans; Peptide Transporter 1; Protein Binding; Rats; Symporters

2005
Three-dimensional quantitative structure-activity relationship analyses of beta-lactam antibiotics and tripeptides as substrates of the mammalian H+/peptide cotransporter PEPT1.
    Journal of medicinal chemistry, 2005, Jun-30, Volume: 48, Issue:13

    Topics: Animals; beta-Lactams; Cell Line, Tumor; Dipeptides; Drug Design; Humans; Mammals; Models, Molecular; Oligopeptides; Peptide Transporter 1; Quantitative Structure-Activity Relationship; Substrate Specificity; Symporters

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010