Page last updated: 2024-09-04

cdri 85-287 and tamoxifen

cdri 85-287 has been researched along with tamoxifen in 6 studies

Compound Research Comparison

Studies
(cdri 85-287)
Trials
(cdri 85-287)
Recent Studies (post-2010)
(cdri 85-287)
Studies
(tamoxifen)
Trials
(tamoxifen)
Recent Studies (post-2010) (tamoxifen)
220320,6302,2276,256

Protein Interaction Comparison

ProteinTaxonomycdri 85-287 (IC50)tamoxifen (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.46
Serine/threonine-protein kinase D3Homo sapiens (human)1
Bile salt export pumpHomo sapiens (human)10
Epidermal growth factor receptorHomo sapiens (human)3.553
Estrogen receptorHomo sapiens (human)0.9266
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)2.949
Protein kinase C gamma typeHomo sapiens (human)1
Protein kinase C beta typeHomo sapiens (human)1
Tyrosine-protein kinase LckHomo sapiens (human)8.033
Tyrosine-protein kinase FynHomo sapiens (human)1.195
Progesterone receptorHomo sapiens (human)0.1288
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.472
Muscarinic acetylcholine receptor M2Homo sapiens (human)7.793
Muscarinic acetylcholine receptor M4Homo sapiens (human)4.817
ATP-dependent translocase ABCB1Homo sapiens (human)6.4
Muscarinic acetylcholine receptor M5Homo sapiens (human)2.585
Alpha-2A adrenergic receptorHomo sapiens (human)1.935
Adenosine receptor A3Homo sapiens (human)3.701
Muscarinic acetylcholine receptor M1Homo sapiens (human)2.829
Steroid hormone receptor ERR1Homo sapiens (human)0.2
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)0.967
Beta-3 adrenergic receptorHomo sapiens (human)7.703
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)3.701
Protein kinase C alpha typeHomo sapiens (human)1
Alpha-2B adrenergic receptorHomo sapiens (human)3.518
Muscarinic acetylcholine receptor M3Homo sapiens (human)2.974
Substance-K receptorHomo sapiens (human)3.67
D(1A) dopamine receptorHomo sapiens (human)8.502
Prostaglandin G/H synthase 1Homo sapiens (human)4.391
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.472
Thromboxane-A synthase Homo sapiens (human)0.916
Protein kinase C eta typeHomo sapiens (human)1
Histamine H2 receptorHomo sapiens (human)9.396
Alpha-1D adrenergic receptorHomo sapiens (human)4.982
5-hydroxytryptamine receptor 2AHomo sapiens (human)4.801
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.46
Adenosine receptor A2aHomo sapiens (human)7.099
Sodium-dependent serotonin transporterHomo sapiens (human)2.334
D(3) dopamine receptorHomo sapiens (human)1.072
5-hydroxytryptamine receptor 2BHomo sapiens (human)2.084
Protein kinase C iota typeHomo sapiens (human)1
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)3.701
5-hydroxytryptamine receptor 6Homo sapiens (human)2.679
Estrogen-related receptor gammaHomo sapiens (human)0.0622
Sodium-dependent dopamine transporter Homo sapiens (human)1.841
Protein kinase C epsilon typeHomo sapiens (human)1
Protein kinase C theta typeHomo sapiens (human)1
Protein kinase C zeta typeHomo sapiens (human)1
Protein kinase C delta typeHomo sapiens (human)1
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.2759
Platelet-activating factor acetylhydrolaseHomo sapiens (human)0.904
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)0.012
Serine/threonine-protein kinase D1Homo sapiens (human)1
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)0.967
Estrogen receptor betaHomo sapiens (human)0.7809
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.021
7-dehydrocholesterol reductaseHomo sapiens (human)0.012

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kon, OL; Ng, SC; Sim, KY; Teo, CC1
Durani, S; Kapil, RS; Saeed, A; Sharma, AP2
Blair, HC; Jordan, SE; McDonald, JM; McKenna, MA; Radding, W; Williams, JP1
Arshad, M; Ghosh, R; Sawlani, V; Sengupta, S; Sharma, S; Singh, MM1
Dalela, D; Gupta, G; Jain, A; Jain, RK; Kumar, R; Maikhuri, JP; Sarswat, A; Sharma, VL; Verma, V1

Other Studies

6 other study(ies) available for cdri 85-287 and tamoxifen

ArticleYear
Synthesis of 2-(p-chlorobenzyl)-3-aryl-6-methoxybenzofurans as selective ligands for antiestrogen-binding sites. Effects on cell proliferation and cholesterol synthesis.
    Journal of medicinal chemistry, 1992, Apr-17, Volume: 35, Issue:8

    Topics: Benzofurans; Binding Sites; Binding, Competitive; Cell Division; Cell Line; Cholesterol; Estrogen Antagonists; Humans; Ligands; Receptors, Estrogen; Thymidine

1992
Structure-activity relationship of antiestrogens. Phenolic analogues of 2,3-diaryl-2H-1-benzopyrans.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:12

    Topics: Animals; Benzopyrans; Binding, Competitive; Chemical Phenomena; Chemistry; Cytosol; Estrogen Antagonists; Female; Mice; Molecular Structure; Organ Size; Phenols; Piperidines; Rats; Receptors, Estrogen; Structure-Activity Relationship; Uterus

1990
Structure-activity relationship of antiestrogens. Effect of the side chain and its position on the activity of 2,3-diaryl-2H-1-benzopyrans.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:12

    Topics: Animals; Benzopyrans; Binding, Competitive; Chemical Phenomena; Chemistry; Cytosol; Estrogen Antagonists; Female; Mice; Microsomes, Liver; Molecular Structure; Organ Size; Piperidines; Pyrrolidines; Rats; Receptors, Estrogen; Structure-Activity Relationship; Tamoxifen; Thiophenes; Uterus

1990
Differential effects of tamoxifen-like compounds on osteoclastic bone degradation, H(+)-ATPase activity, calmodulin-dependent cyclic nucleotide phosphodiesterase activity, and calmodulin binding.
    Journal of cellular biochemistry, 1997, Sep-01, Volume: 66, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Benzopyrans; Bone Resorption; Calmodulin; Centchroman; Cyclic Nucleotide Phosphodiesterases, Type 1; Dose-Response Relationship, Drug; Female; Osteoclasts; Phosphoric Diester Hydrolases; Piperidines; Proton-Translocating ATPases; Tamoxifen; Trifluoperazine

1997
In vitro anti-resorptive activity and prevention of ovariectomy-induced osteoporosis in female Sprague-Dawley rats by ormeloxifene, a selective estrogen receptor modulator.
    The Journal of steroid biochemistry and molecular biology, 2004, Volume: 91, Issue:1-2

    Topics: Animals; Autopsy; Benzopyrans; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Calcium; Centchroman; Chick Embryo; Densitometry; Disease Models, Animal; Epithelial Cells; Ethinyl Estradiol; Female; Femur; Osteocalcin; Osteoporosis; Ovary; Parathyroid Hormone; Piperidines; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Tamoxifen; Tibia

2004
Selective estrogen receptor modulators regulate stromal proliferation in human benign prostatic hyperplasia by multiple beneficial mechanisms--action of two new agents.
    Investigational new drugs, 2012, Volume: 30, Issue:2

    Topics: 5-alpha Reductase Inhibitors; Animals; Apoptosis; Aromatase; Benzopyrans; Cell Proliferation; Cell Survival; Cells, Cultured; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Finasteride; Gene Expression Regulation; Humans; Male; Piperidines; Prostate; Prostatic Hyperplasia; Rats; Rats, Sprague-Dawley; Receptors, Androgen; RNA, Messenger; Selective Estrogen Receptor Modulators; Signal Transduction; Stromal Cells; Tamoxifen; Testosterone; Tissue Culture Techniques

2012