Page last updated: 2024-09-03

cdp 840 and l-454,560

cdp 840 has been researched along with l-454,560 in 2 studies

Compound Research Comparison

Studies (cdp 840)	Trials (cdp 840)	Recent Studies (post-2010) (cdp 840)	Studies (l-454,560)	Trials (l-454,560)	Recent Studies (post-2010) (l-454,560)
18	0	3	10	0	1

Protein Interaction Comparison

Protein	Taxonomy	l-454,560 (IC50)
Cytochrome P450 2C9	Homo sapiens (human)	0.4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)	0.0011
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)	0.0008
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Homo sapiens (human)	0.0037
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)	0.001

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bateman, K; Boulet, L; Chan, CC; Charleson, S; Chauret, N; Claveau, D; Day, S; Deschênes, D; Dubé, D; Ethier, D; Gallant, M; Girard, Y; Huang, Z; Lacombe, P; Laliberté, F; Li, C; Liu, S; Macdonald, D; Mancini, J; Masson, P; Mastracchio, A; Muise, E; Nicholson, D; Nicoll-Griffith, DA; Perrier, H; Pon, D; Roy, B; Scheigetz, J; Silva, JM; Styhler, A; Trimble, LA; Turner, M; Young, RN	1
Jabaris, SS; Kodimuthali, A; Pal, M	1

Reviews

1 review(s) available for cdp 840 and l-454,560

Article	Year
Recent advances on phosphodiesterase 4 inhibitors for the treatment of asthma and chronic obstructive pulmonary disease. Journal of medicinal chemistry, 2008, Sep-25, Volume: 51, Issue:18 Topics: Asthma; Humans; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Pulmonary Disease, Chronic Obstructive	2008

Other Studies

1 other study(ies) available for cdp 840 and l-454,560

Article	Year
Discovery of a substituted 8-arylquinoline series of PDE4 inhibitors: structure-activity relationship, optimization, and identification of a highly potent, well tolerated, PDE4 inhibitor. Bioorganic & medicinal chemistry letters, 2005, Dec-01, Volume: 15, Issue:23 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Bronchoconstriction; Cyclic Nucleotide Phosphodiesterases, Type 4; Guinea Pigs; Humans; Inhibitory Concentration 50; Phosphodiesterase Inhibitors; Quinolines; Rats; Saimiri; Sheep; Structure-Activity Relationship; Vomiting	2005

Article

Year

Discovery of a substituted 8-arylquinoline series of PDE4 inhibitors: structure-activity relationship, optimization, and identification of a highly potent, well tolerated, PDE4 inhibitor.

Bioorganic & medicinal chemistry letters, 2005, Dec-01, Volume: 15, Issue:23

Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Bronchoconstriction; Cyclic Nucleotide Phosphodiesterases, Type 4; Guinea Pigs; Humans; Inhibitory Concentration 50; Phosphodiesterase Inhibitors; Quinolines; Rats; Saimiri; Sheep; Structure-Activity Relationship; Vomiting

2005