ccg-50014 and celastrol

ccg-50014 has been researched along with celastrol* in 1 studies

Other Studies

1 other study(ies) available for ccg-50014 and celastrol

ArticleYear
Natural Products Discovered in a High-Throughput Screen Identified as Inhibitors of RGS17 and as Cytostatic and Cytotoxic Agents for Lung and Prostate Cancer Cell Lines.
    Journal of natural products, 2017, 07-28, Volume: 80, Issue:7

    Regulator of G Protein Signaling (RGS) 17 is an overexpressed promoter of cancer survival in lung and prostate tumors, the knockdown of which results in decreased tumor cell proliferation in vitro. Identification of drug-like molecules inhibiting this protein could ameliorate the RGS17's pro-tumorigenic effect. Using high-throughput screening, a chemical library containing natural products was interrogated for inhibition of the RGS17-Gα

    Topics: Benzophenanthridines; Biological Products; Cytostatic Agents; Cytotoxins; GTP-Binding Protein Regulators; Humans; Isoquinolines; Lung Neoplasms; Male; Molecular Structure; Pentacyclic Triterpenes; Prostatic Neoplasms; Triterpenes

2017