cathepsin-g and cloricromen

cathepsin-g has been researched along with cloricromen* in 1 studies

Other Studies

1 other study(ies) available for cathepsin-g and cloricromen

Article	Year
Polymorphonuclear leukocyte-dependent modulation of platelet function: effect of cloricromene. European journal of pharmacology, 1991, May-30, Volume: 198, Issue:1 Cloricromene inhibits the activation of platelets and polymorphonuclear leukocytes (PMN) induced by specific stimuli. We report here that cloricromene caused a concentration-dependent reduction of platelet aggregation, beta-thromboglobulin (beta-TG) release and cytoplasmic Ca2+ movements induced by PMN stimulated with N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP), and enhanced the inhibitory action of unstimulated PMN on platelet responses to the stable endoperoxide analog U46619. These effects may be of pharmacological interest in view of the multiple interactions between platelets and leukocytes that occur in thrombotic and inflammatory diseases. Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; beta-Thromboglobulin; Blood Platelets; Calcium; Cathepsin G; Cathepsins; Chromonar; Cytoplasm; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activation; Prostaglandin Endoperoxides, Synthetic; Serine Endopeptidases	1991

Article

Year

Polymorphonuclear leukocyte-dependent modulation of platelet function: effect of cloricromene.

European journal of pharmacology, 1991, May-30, Volume: 198, Issue:1

Cloricromene inhibits the activation of platelets and polymorphonuclear leukocytes (PMN) induced by specific stimuli. We report here that cloricromene caused a concentration-dependent reduction of platelet aggregation, beta-thromboglobulin (beta-TG) release and cytoplasmic Ca2+ movements induced by PMN stimulated with N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP), and enhanced the inhibitory action of unstimulated PMN on platelet responses to the stable endoperoxide analog U46619. These effects may be of pharmacological interest in view of the multiple interactions between platelets and leukocytes that occur in thrombotic and inflammatory diseases.

Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; beta-Thromboglobulin; Blood Platelets; Calcium; Cathepsin G; Cathepsins; Chromonar; Cytoplasm; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activation; Prostaglandin Endoperoxides, Synthetic; Serine Endopeptidases

1991