catechin and theaflavin-3,3'-digallate

catechin has been researched along with theaflavin-3,3'-digallate in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.57)18.2507
2000's0 (0.00)29.6817
2010's16 (57.14)24.3611
2020's11 (39.29)2.80

Authors

AuthorsStudies
Ho, CT; Lin, JK; Lin, YL; Lin-Shiau, SY; Tsai, SH1
Isaacs, CE; Xu, W1
Ishii, M; Iwamoto, Y; Kato, S; Katsuoka, F; Kawaguchi, S; Kobayashi, Y; Nakamura, T; Nishikawa, K; Takayanagi, H; Tsujita, T; Yamamoto, M1
Bannister, TD; Bradley, KA; Chase, P; Colicelli, J; Damoiseaux, R; Fernández-Vega, V; Graeber, TG; Hodder, P; Nair, R; Scampavia, L; Spicer, TP; Ting, PY; Titz, B1
Bian, ZX; Chen, ZY; Huang, Y; Ping Leung, F; San Cheang, W; Tak Wong, W; Wai Lau, C; Yen Tam, Y; Yu Tian, X; Yuen Ngai, C; Zhang, Y1
Grenier, D; Lombardo Bedran, TB; Morin, MP; Palomari Spolidorio, D1
Chen, YC; Gao, Y; Rankin, GO; Tu, Y1
Chen, YC; Gao, Y; Kim, E; Li, B; Rankin, GO; Tu, Y1
Glisan, SL; Grove, KA; Lambert, JD; Yennawar, NH1
Hu, B; Lei, S; Saeeduddin, M; Sun, Y; Xie, M; Zeng, X; Zhang, H; Zhou, L1
Gan, M; Geng, D; Hu, X; Ping, Z; Shi, J; Tao, Y; Wang, L; Wang, Z; Wu, X; Xu, Y; Yang, H; Zhang, W1
Jin, F; Li, F; Ren, Z; Wang, L; Wang, Q; Wang, Y; Wu, Y1
Chen, YC; Kim, E; Pan, H; Rankin, GO; Rojanasakul, Y; Tu, Y1
Honjoh, K; Masuda, Y; Maung, AT; Miyamoto, T; Noor Mohammadi, T; Sato, J; Sonoda, T1
Chen, YC; Gao, Y; Tu, Y; Yin, J1
Chen, Q; Fu, G; Jin, C; Jin, T; Lu, J; Qiu, F; Shen, Z; Wang, M; Ying, H; Zhang, W; Zhao, Y1
Deng, X; Guo, Y; Liu, X; Niu, X; Teng, Z; Wang, J; Yu, Q; Zhang, J1
Bruins, ME; de Bruijn, WJC; Liu, Z; Vincken, JP1
Jiang, X; Jiao, Z; Li, L; Liu, M; Liu, Y; Ma, Z; Qin, J; Qin, L; Shi, W; Sun, H; Ye, H; Yu, Z; Zhang, G; Zhang, X; Zhao, L; Zhou, H1
Goc, A; Niedzwiecki, A; Rath, M; Sumera, W1
Huang, Q; Jiang, Y; Jin, W; Li, J1
Bagchi, A; Bhattacharjee, D; Chakrabarti, P; Chatterjee, M; Chatterjee, S; Chattopadhyay, A; Ghosh, A; Misra, S; Mondal, S; Niyogi, S; Saha, A; Sarkar, A; Sinhamahapatra, P1
Cai, X; Li, S; Luo, L; Wang, J; Wang, M; Yu, X; Zeng, L1
Huang, J; Liu, C; Liu, Y; Liu, Z; Wang, F; Xu, G; Zhang, S; Zhao, Q; Zhao, S; Zhou, J1
Bai, Y; Fan, H; He, J; He, Q; Hu, J; Sun, Y; Xu, Z; Yang, G; Yao, G; Zhang, J; Zhang, T1
Chen, YC; He, P; Kim, E; Li, B; Pan, H; Tu, Y; Wu, Y; Zhou, H1
Huang, Q; Jiang, Y; Jin, W; Shi, Y; Zheng, T1
Liu, X; Tu, Y; Warusawitharana, HK; Xia, C; Yang, Y; Zhou, H1

Other Studies

28 other study(ies) available for catechin and theaflavin-3,3'-digallate

ArticleYear
Theaflavin-3,3'-digallate from black tea blocks the nitric oxide synthase by down-regulating the activation of NF-kappaB in macrophages.
    European journal of pharmacology, 1999, Feb-19, Volume: 367, Issue:2-3

    Topics: Animals; Antioxidants; Biflavonoids; Blotting, Western; Catechin; Cell Line; Down-Regulation; Drug Interactions; Electrophoresis; Flavonoids; Gallic Acid; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Phenols; Plant Extracts; Polymers; Polyphenols; Reverse Transcriptase Polymerase Chain Reaction; Tea

1999
Theaflavin-3,3'-digallate and lactic acid combinations reduce herpes simplex virus infectivity.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:8

    Topics: Animals; Antiviral Agents; Biflavonoids; Catechin; Chlorocebus aethiops; Drug Combinations; Drug Evaluation, Preclinical; Female; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Hydrogen-Ion Concentration; Lactic Acid; Semen Analysis; Vagina; Vero Cells; Viral Load; Virus Inactivation

2013
DNA methyltransferase 3a regulates osteoclast differentiation by coupling to an S-adenosylmethionine-producing metabolic pathway.
    Nature medicine, 2015, Volume: 21, Issue:3

    Topics: Animals; Biflavonoids; Bone Resorption; Catechin; Cell Differentiation; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Down-Regulation; Gene Expression; Mice; Osteoclasts; Osteogenesis; RANK Ligand; S-Adenosylmethionine; Transcription Factors

2015
Identification of small molecules that disrupt signaling between ABL and its positive regulator RIN1.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Biflavonoids; Catechin; Fluorescence Resonance Energy Transfer; Fusion Proteins, bcr-abl; High-Throughput Screening Assays; Humans; Intracellular Signaling Peptides and Proteins; K562 Cells; Mitogen-Activated Protein Kinase 1; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Time Factors

2015
Black tea protects against hypertension-associated endothelial dysfunction through alleviation of endoplasmic reticulum stress.
    Scientific reports, 2015, May-15, Volume: 5

    Topics: Angiotensin II; Animals; Aorta; Biflavonoids; Blood Pressure; Camellia sinensis; Capillary Resistance; Catechin; Cells, Cultured; Endoplasmic Reticulum Stress; Endothelial Cells; Endothelium, Vascular; Homocysteine; Hyperhomocysteinemia; Hypertension; Male; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tea; Vasodilation

2015
Black Tea Extract and Its Theaflavin Derivatives Inhibit the Growth of Periodontopathogens and Modulate Interleukin-8 and β-Defensin Secretion in Oral Epithelial Cells.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: beta-Defensins; Biflavonoids; Catechin; Cell Line; Epithelial Cells; Humans; Interleukin-8; Lipopolysaccharides; Microbial Sensitivity Tests; Mouth; Plant Extracts; Porphyromonas gingivalis; Tea

2015
Theaflavin-3, 3'-digallate decreases human ovarian carcinoma OVCAR-3 cell-induced angiogenesis via Akt and Notch-1 pathways, not via MAPK pathways.
    International journal of oncology, 2016, Volume: 48, Issue:1

    Topics: Biflavonoids; Carcinoma; Catechin; Cell Line, Tumor; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mitogen-Activated Protein Kinase Kinases; Neovascularization, Pathologic; Oncogene Protein v-akt; Ovarian Neoplasms; Proto-Oncogene Proteins c-myc; Receptor, Notch1; Signal Transduction; Vascular Endothelial Growth Factor A

2016
Theaflavin-3, 3'-digallate induces apoptosis and G2 cell cycle arrest through the Akt/MDM2/p53 pathway in cisplatin-resistant ovarian cancer A2780/CP70 cells.
    International journal of oncology, 2016, Volume: 48, Issue:6

    Topics: Apoptosis; Biflavonoids; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Drug Resistance, Neoplasm; Female; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-mdm2; Signal Transduction; Tumor Suppressor Protein p53

2016
Inhibition of pancreatic lipase by black tea theaflavins: Comparative enzymology and in silico modeling studies.
    Food chemistry, 2017, Feb-01, Volume: 216

    Topics: Animals; Biflavonoids; Camellia sinensis; Catechin; Computer Simulation; Enzyme Inhibitors; Lipase; Pancreas; Protein Structure, Secondary; Protein Structure, Tertiary; Swine; Tea

2017
Effective synthesis of theaflavin-3,3'-digallate with epigallocatechin-3-O-gallate and epicatechin gallate as substrates by using immobilized pear polyphenol oxidase.
    International journal of biological macromolecules, 2017, Volume: 94, Issue:Pt A

    Topics: Biflavonoids; Biocatalysis; Catechin; Catechol Oxidase; Cross-Linking Reagents; Enzymes, Immobilized; Equipment Reuse; Ferrosoferric Oxide; Glutaral; Kinetics; Metal Nanoparticles; Plant Proteins; Protein Multimerization; Pyrus; Substrate Specificity

2017
Theaflavin-3,3'-digallate represses osteoclastogenesis and prevents wear debris-induced osteolysis via suppression of ERK pathway.
    Acta biomaterialia, 2017, 01-15, Volume: 48

    Topics: Animals; Biflavonoids; Bone Resorption; Catechin; Gene Expression Regulation; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; RANK Ligand; RAW 264.7 Cells; Skull; Titanium

2017
In vitro and in vivo anti-inflammatory effects of theaflavin-3,3'-digallate on lipopolysaccharide-induced inflammation.
    European journal of pharmacology, 2017, Jan-05, Volume: 794

    Topics: Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents; Biflavonoids; Catechin; Cell Line, Tumor; Cell Nucleus; Gene Expression Regulation; Humans; Inflammation; Interleukin-1beta; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Lung; MAP Kinase Signaling System; Mice; NF-kappa B; p38 Mitogen-Activated Protein Kinases; RAW 264.7 Cells; RNA, Messenger; Tumor Necrosis Factor-alpha

2017
Theaflavin-3,3'-Digallate Enhances the Inhibitory Effect of Cisplatin by Regulating the Copper Transporter 1 and Glutathione in Human Ovarian Cancer Cells.
    International journal of molecular sciences, 2018, Jan-02, Volume: 19, Issue:1

    Topics: Biflavonoids; Catechin; Cation Transport Proteins; Cell Line, Tumor; Cisplatin; Copper Transporter 1; DNA Adducts; DNA Damage; Drug Synergism; Female; Glutathione; Humans; Ovarian Neoplasms; Up-Regulation

2018
Mechanism for antibacterial action of epigallocatechin gallate and theaflavin-3,3'-digallate on Clostridium perfringens.
    Journal of applied microbiology, 2019, Volume: 126, Issue:2

    Topics: Anti-Bacterial Agents; Biflavonoids; Catechin; Clostridium perfringens

2019
Theaflavin-3,3'-Digallate Suppresses Human Ovarian Carcinoma OVCAR-3 Cells by Regulating the Checkpoint Kinase 2 and p27 kip1 Pathways.
    Molecules (Basel, Switzerland), 2019, Feb-14, Volume: 24, Issue:4

    Topics: Antioxidants; Apoptosis; Biflavonoids; Camellia sinensis; Carcinoma; Catechin; Cell Line, Tumor; Checkpoint Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Female; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tea; Tumor Suppressor Protein p53

2019
Theaflavin 3,3'-digallate reverses the downregulation of connexin 43 and autophagy induced by high glucose via AMPK activation in cardiomyocytes.
    Journal of cellular physiology, 2019, Volume: 234, Issue:10

    Topics: AMP-Activated Protein Kinases; Animals; Animals, Newborn; Autophagy; Biflavonoids; Cardiotoxicity; Catechin; Cells, Cultured; Connexin 43; Enzyme Activation; Gap Junctions; Glucose; Myocytes, Cardiac; Rats, Sprague-Dawley; Signal Transduction

2019
Theaflavin-3,3´-digallate increases the antibacterial activity of β-lactam antibiotics by inhibiting metallo-β-lactamase activity.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:10

    Topics: Animals; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Biflavonoids; Binding Sites; Catechin; Cephalothin; Female; Hydrolysis; Methicillin-Resistant Staphylococcus aureus; Mice, Inbred BALB C; Microbial Sensitivity Tests; Models, Molecular; Pneumonia; Staphylococcal Infections

2019
Microbial Metabolism of Theaflavin-3,3'-digallate and Its Gut Microbiota Composition Modulatory Effects.
    Journal of agricultural and food chemistry, 2021, Jan-13, Volume: 69, Issue:1

    Topics: Adult; Bacteria; Biflavonoids; Camellia sinensis; Catechin; Feces; Female; Gastrointestinal Microbiome; Humans; Male; Molecular Structure; Phylogeny; Young Adult

2021
Hyperactivation of HER2-SHCBP1-PLK1 axis promotes tumor cell mitosis and impairs trastuzumab sensitivity to gastric cancer.
    Nature communications, 2021, 05-14, Volume: 12, Issue:1

    Topics: Animals; Antineoplastic Agents, Immunological; Biflavonoids; Catechin; Cell Cycle Proteins; Cell Line, Tumor; Cell Nucleus; Drug Resistance, Neoplasm; Female; Gene Knockdown Techniques; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Mice; Microfilament Proteins; Middle Aged; Mitosis; Models, Biological; Models, Molecular; Phosphoproteins; Polo-Like Kinase 1; Prognosis; Protein Interaction Domains and Motifs; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Receptor, ErbB-2; Shc Signaling Adaptor Proteins; Signal Transduction; Stomach Neoplasms; Trastuzumab; Xenograft Model Antitumor Assays

2021
Phenolic compounds disrupt spike-mediated receptor-binding and entry of SARS-CoV-2 pseudo-virions.
    PloS one, 2021, Volume: 16, Issue:6

    Topics: A549 Cells; Angiotensin-Converting Enzyme 2; Benzopyrans; Biflavonoids; Catechin; Cell Survival; COVID-19; Curcumin; Humans; Polyphenols; Protein Binding; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Virion; Virus Attachment; Virus Internalization

2021
Associations between caseinophosphopeptides and theaflavin-3,3'-digallate and their impact on cellular antioxidant activity.
    Food & function, 2021, Aug-21, Volume: 12, Issue:16

    Topics: Antioxidants; Biflavonoids; Caseins; Catechin; Cell Line, Tumor; Chromatography, High Pressure Liquid; Humans; Peptide Fragments; Scattering, Small Angle

2021
Methotrexate and theaflavin-3, 3'-digallate synergistically restore the balance between apoptosis and autophagy in synovial fibroblast of RA: an ex vivo approach with cultured human RA FLS.
    Inflammopharmacology, 2021, Volume: 29, Issue:5

    Topics: Adult; Antirheumatic Agents; Apoptosis; Arthritis, Rheumatoid; Autophagy; Biflavonoids; Catechin; Cells, Cultured; Disease Progression; Drug Synergism; Female; Fibroblasts; Humans; Inhibitory Concentration 50; Male; Methotrexate; Middle Aged; Osteoarthritis; Synovial Fluid; Synoviocytes

2021
Studies on the interactions of theaflavin-3,3'-digallate with bovine serum albumin: Multi-spectroscopic analysis and molecular docking.
    Food chemistry, 2022, Jan-01, Volume: 366

    Topics: Biflavonoids; Binding Sites; Catechin; Circular Dichroism; Molecular Docking Simulation; Protein Binding; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Thermodynamics

2022
Improved yield of theaflavin-3,3'-digallate from Bacillus megaterium tyrosinase via directed evolution.
    Food chemistry, 2022, May-01, Volume: 375

    Topics: Bacillus megaterium; Biflavonoids; Camellia sinensis; Catechin; Monophenol Monooxygenase; Tea

2022
Theaflavin 3, 3'-Digallate Delays Ovarian Aging by Improving Oocyte Quality and Regulating Granulosa Cell Function.
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: Aging; Animals; Biflavonoids; Catechin; Estrous Cycle; Female; Granulosa Cells; Humans; Mice; Oocytes; Ovary; Reactive Oxygen Species

2021
Simultaneous Tests of Theaflavin-3,3'-digallate as an Anti-Diabetic Drug in Human Hepatoma G2 Cells and Zebrafish (
    Nutrients, 2021, Dec-07, Volume: 13, Issue:12

    Topics: Animals; Biflavonoids; Catechin; Dose-Response Relationship, Drug; Down-Regulation; Drug Evaluation, Preclinical; Glucokinase; Glucose; Hep G2 Cells; Humans; Hypoglycemic Agents; Phosphoenolpyruvate Carboxykinase (ATP); Tea; Up-Regulation; Zebrafish

2021
Enhancing Intestinal Permeability of Theaflavin-3,3'-digallate by Chitosan-Caseinophosphopeptides Nanocomplexes.
    Journal of agricultural and food chemistry, 2022, Feb-16, Volume: 70, Issue:6

    Topics: Antioxidants; Biflavonoids; Caco-2 Cells; Catechin; Chitosan; Humans; Permeability; Tea

2022
The Prevention Role of Theaflavin-3,3'-digallate in Angiotensin II Induced Pathological Cardiac Hypertrophy via CaN-NFAT Signal Pathway.
    Nutrients, 2022, Mar-26, Volume: 14, Issue:7

    Topics: Angiotensin II; Antioxidants; Biflavonoids; Calcineurin; Cardiomegaly; Catechin; Heart Failure; Humans; Myocytes, Cardiac; Signal Transduction

2022