catechin has been researched along with limbrel in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (5.71) | 29.6817 |
| 2010's | 29 (82.86) | 24.3611 |
| 2020's | 4 (11.43) | 2.80 |
| Authors | Studies |
|---|---|
| Burnett, BP; Khokhlov, A; Levy, RM; Saikovsky, R; Shmidt, E | 1 |
| Aguennouz, M; Altavilla, D; Bitto, A; De Pasquale, MG; Irrera, N; Mazzeo, A; Messina, S; Migliorato, A; Musarò, A; Naro, A; Polito, F; Rizzuto, E; Russo, M; Squadrito, F; Vita, G; Vita, GL | 1 |
| Burnett, BP; Levy, RM; Pillai, L | 1 |
| Burnett, BP; Jia, Q; Levy, RM; Pillai, L; Yimam, M; Zhao, Y | 1 |
| McLain, DA; Schumock, GT; Walton, SM | 1 |
| Bart, B; Bell, M; Burnett, BP; Caldron, P; Ermolova, T; Kantemirova, R; Khokhlov, A; Kopenkin, S; Levy, RM; Mazurov, V; Pillai, L | 1 |
| Bart, B; Bell, M; Burnett, B; Caldron, P; Ermolova, T; Kantemirova, R; Khokhlov, A; Kopenkin, S; Levy, R; Mazurov, V; Pillai, L | 1 |
| Altavilla, D; Bitto, A; Fazzari, C; Irrera, N; Minutoli, L; Polito, F; Squadrito, F | 1 |
| Gottlieb, D; Kuritzky, L | 1 |
| Altavilla, D; Bitto, A; Burnett, BP; Levy, RM; Pillai, L; Squadrito, F | 1 |
| Altavilla, D; Bitto, A; David, A; Irrera, N; Minutoli, L; Rinaldi, M; Squadrito, F; Venuti, FS | 1 |
| Altavilla, D; Arena, S; Bitto, A; Burnett, BP; Irrera, N; Magno, C; Minutoli, L; Polito, F; Rinaldi, M; Squadrito, F | 1 |
| Lopez, HL | 1 |
| Barnhart, H; Bonkovsky, H; Chalasani, N; Fontana, R; Hoofnagle, JH; Kleiner, DE; Navarro, V; Vuppalanchi, R | 1 |
| Jüni, P; Reichenbach, S | 1 |
| Atienza, J; Kumar, A; Metersky, ML; Panduranga, V | 1 |
| Chopra, K; Singh, DP | 1 |
| Altavilla, D; Bitto, A; Galfo, F; Irrera, N; Mecchio, A; Pallio, G; Pizzino, G; Squadrito, F | 1 |
| Adamo, EB; Altavilla, D; Bitto, A; Calò, M; Galfo, F; Interdonato, M; Irrera, N; Marini, H; Minutoli, L; Pallio, G; Pizzino, G; Rinaldi, M; Squadrito, F; Trichilo, V | 1 |
| El-Kashef, DH; El-Kenawi, AE; Salem, HA; Suddek, GM | 1 |
| Ammar, el-SM; El-Sheakh, AR; Ghoneim, HA; Suddek, GM | 1 |
| Altavilla, D; Arena, S; Bitto, A; Bruschetta, D; Galfo, F; Germanà, A; Irrera, N; Laurà, R; Magno, C; Marini, H; Mecchio, A; Micali, A; Minutoli, L; Pallio, G; Pisani, A; Pizzino, G; Puzzolo, D; Rinaldi, M; Squadrito, F | 1 |
| Ganea, D; Hooper, KM; Kong, W | 1 |
| Altavilla, D; Arcoraci, V; Bitto, A; Galfo, F; Irrera, N; Macrì, A; Minutoli, L; Pallio, G; Pizzino, G; Squadrito, F; Squadrito, G | 1 |
| Altavilla, D; Bitto, A; Canalini, F; Giuliani, D; Guarini, S; Irrera, N; Minutoli, L; Ottani, A; Pallio, G; Rinaldi, M; Squadrito, F; Vandini, E; Zaffe, D | 1 |
| Altavilla, D; Bitto, A; Irrera, N; Lombardo, D; Minutoli, L; Musolino, C; Pollicino, T; Raimondo, G; Squadrito, F; Squadrito, G; Timmoneri, M | 1 |
| Chirumbolo, S | 1 |
| Abdеlaziz, RR; Suddek, GM; Еlmahdy, MK | 1 |
| Cao, V; Lin, TK; Oh, A; Wilson, L | 1 |
| Monro, JA; Puri, BK; White, N | 1 |
| Curtis, JR; Owensby, JK; Xie, F | 1 |
| El-Kashef, DH; Mohamed, NI; Suddek, GM | 1 |
| Altavilla, D; Irrera, N; Mannino, F; Minutoli, L; Oteri, G; Pallio, G; Picciolo, G; Squadrito, F; Vaccaro, M | 1 |
| Abdelaziz, RR; Elsayed, FF; Elshenawy, WM; Khalifa, EM; Rizq, MR | 1 |
3 review(s) available for catechin and limbrel
| Article | Year |
|---|---|
Nutritional interventions to prevent and treat osteoarthritis. Part II: focus on micronutrients and supportive nutraceuticals.
Topics: Animals; Catechin; Dietary Supplements; Disease Progression; Drug Combinations; Epigenesis, Genetic; Harpagophytum; Humans; Hyaluronic Acid; Micronutrients; Osteoarthritis; Oxidative Stress; Peptide Hydrolases; Proteomics; S-Adenosylmethionine; Viscosupplements; Vitamins | 2012 |
Flavocoxid, a nutraceutical approach to blunt inflammatory conditions.
Topics: Acacia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Catechin; Drug Combinations; Humans; Inflammation; Osteoarthritis; Scutellaria baicalensis | 2014 |
A gray area for reimbursement: medical foods for non-inborn errors of metabolism.
Topics: Catechin; Dietary Supplements; Drug Combinations; Female; Humans; Insurance Coverage; Insurance, Health, Reimbursement; Male; Metabolic Syndrome; Nutritive Value; Qualitative Research | 2018 |
4 trial(s) available for catechin and limbrel
| Article | Year |
|---|---|
Flavocoxid is as effective as naproxen for managing the signs and symptoms of osteoarthritis of the knee in humans: a short-term randomized, double-blind pilot study.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Double-Blind Method; Drug Combinations; Female; Flavonoids; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pain; Pain Measurement; Phytotherapy; Pilot Projects; Plant Extracts; Scutellaria | 2009 |
Flavocoxid, an anti-inflammatory agent of botanical origin, does not affect coagulation or interact with anticoagulation therapies.
Topics: Adult; Aged; Animals; Anticoagulants; Arachidonate 5-Lipoxygenase; Aspirin; Bleeding Time; Catechin; Cyclooxygenase 1; Cyclooxygenase 2; Drug Combinations; Drug Evaluation, Preclinical; Drug Interactions; Drug Therapy, Combination; Female; Humans; International Normalized Ratio; Male; Mice; Mice, Inbred ICR; Middle Aged; Osteoarthritis; Platelet Aggregation | 2010 |
Efficacy and safety of flavocoxid, a novel therapeutic, compared with naproxen: a randomized multicenter controlled trial in subjects with osteoarthritis of the knee.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Combinations; Female; Gastrointestinal Diseases; Humans; Lipoxygenase Inhibitors; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Respiratory Tract Diseases | 2010 |
Efficacy and safety of flavocoxid compared with naproxen in subjects with osteoarthritis of the knee- a subset analysis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Double-Blind Method; Drug Combinations; Female; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pain; Pain Measurement; Treatment Outcome | 2010 |
28 other study(ies) available for catechin and limbrel
| Article | Year |
|---|---|
Flavocoxid counteracts muscle necrosis and improves functional properties in mdx mice: a comparison study with methylprednisolone.
Topics: Animals; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Catechin; Creatine Kinase; Cytokines; DNA; Drug Combinations; Electrophoretic Mobility Shift Assay; Hydrogen Peroxide; Immunohistochemistry; Male; Methylprednisolone; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophies; Necrosis; NF-kappa B; Peroxidase; Prostaglandin-Endoperoxide Synthases; Signal Transduction | 2009 |
GOAL: multicenter, open-label, post-marketing study of flavocoxid, a novel dual pathway inhibitor anti-inflammatory agent of botanical origin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Catechin; Drug Combinations; Gastrointestinal Tract; Humans; Movement; Osteoarthritis; Product Surveillance, Postmarketing; Quality of Life | 2010 |
Cost analysis of flavocoxid compared to naproxen for management of mild to moderate OA.
Topics: Aged; Aged, 80 and over; Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Comorbidity; Costs and Cost Analysis; Drug Combinations; Hospitalization; Humans; Models, Economic; Naproxen; Osteoarthritis; Severity of Illness Index | 2010 |
Flavocoxid, a dual inhibitor of cyclooxygenase-2 and 5-lipoxygenase, reduces pancreatic damage in an experimental model of acute pancreatitis.
Topics: Acute Disease; Animals; Arachidonate 5-Lipoxygenase; Catechin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Drug Combinations; Gene Expression Regulation; Inflammation; Lipoxygenase Inhibitors; Male; Pancreatitis; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley | 2010 |
Using the medical food flavocoxid [corrected] in managing osteoarthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Catechin; Cyclooxygenase 1; Cyclooxygenase 2; Drug Combinations; Humans; Osteoarthritis, Knee | 2011 |
Flavocoxid inhibits phospholipase A2, peroxidase moieties of the cyclooxygenases (COX), and 5-lipoxygenase, modifies COX-2 gene expression, and acts as an antioxidant.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Catechin; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Combinations; Gene Expression Regulation, Enzymologic; Ibuprofen; In Vitro Techniques; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Male; Membrane Proteins; Osteoarthritis; Peroxidases; Phospholipase A2 Inhibitors; Phospholipases A2; Rats; Rats, Sprague-Dawley | 2011 |
Flavocoxid, a dual inhibitor of COX-2 and 5-LOX of natural origin, attenuates the inflammatory response and protects mice from sepsis.
Topics: Animals; Arrestins; beta-Arrestin 2; beta-Arrestins; Catechin; Cyclooxygenase 2 Inhibitors; Cytokines; Dinoprostone; Disease Models, Animal; Drug Combinations; Extracellular Signal-Regulated MAP Kinases; Intracellular Signaling Peptides and Proteins; Leukotriene B4; Lipoxins; Lipoxygenase Inhibitors; Liver; Lung; Mice, Inbred C57BL; NF-kappa B; Peroxidase; Sepsis | 2012 |
Effects of flavocoxid, a dual inhibitor of COX and 5-lipoxygenase enzymes, on benign prostatic hyperplasia.
Topics: Animals; Apoptosis; Arachidonate 5-Lipoxygenase; bcl-2-Associated X Protein; Caspase 9; Catechin; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Drug Combinations; Epidermal Growth Factor; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Male; Prostatic Hyperplasia; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vascular Endothelial Growth Factor A | 2012 |
Acute liver injury due to flavocoxid (Limbrel), a medical food for osteoarthritis: a case series.
Topics: Aged; Alanine Transaminase; Alkaline Phosphatase; Bilirubin; Catechin; Chemical and Drug Induced Liver Injury; Dietary Supplements; Drug Combinations; Female; Humans; Middle Aged; Osteoarthritis; Prospective Studies | 2012 |
Medical food and food supplements: not always as safe as generally assumed.
Topics: Catechin; Chemical and Drug Induced Liver Injury; Dietary Supplements; Drug Combinations; Humans; Legislation, Food; Osteoarthritis; United States; United States Food and Drug Administration | 2012 |
Summaries for patients. Acute liver injury due to flavocoxid (Limbrel), a medical food for osteoarthritis.
Topics: Aged; Alanine Transaminase; Alkaline Phosphatase; Bilirubin; Catechin; Chemical and Drug Induced Liver Injury; Dietary Supplements; Drug Combinations; Female; Humans; Middle Aged; Osteoarthritis; Prospective Studies | 2012 |
Hypersensitivity pneumonitis due to flavocoxid: are corticosteroids necessary?
Topics: Adrenal Cortex Hormones; Adult; Alveolitis, Extrinsic Allergic; Biopsy; Catechin; Diagnosis, Differential; Drug Combinations; Female; Humans; Osteoarthritis; Tomography, X-Ray Computed | 2013 |
Flavocoxid, dual inhibitor of cyclooxygenase-2 and 5-lipoxygenase, exhibits neuroprotection in rat model of ischaemic stroke.
Topics: Animals; Arachidonate 5-Lipoxygenase; Behavior, Animal; Brain Ischemia; Catechin; Cognition; Cyclooxygenase 2 Inhibitors; Cytokines; Depression; Drug Combinations; Ischemic Attack, Transient; Lipoxygenase Inhibitors; Male; Neuroprotective Agents; Neurotransmitter Agents; Psychomotor Performance; Rats; Rats, Wistar; Stroke | 2014 |
A dual inhibitor of cyclooxygenase and 5-lipoxygenase protects against kainic acid-induced brain injury.
Topics: Animals; Behavior, Animal; Brain Edema; Catechin; Cyclooxygenase Inhibitors; Dinoprostone; Drug Combinations; Hippocampus; Kainic Acid; Leukotriene B4; Lipid Peroxidation; Lipoxygenase Inhibitors; Male; Malondialdehyde; MAP Kinase Signaling System; Nerve Tissue Proteins; Neuroprotective Agents; Neurotoxins; Phosphorylation; Protein Processing, Post-Translational; Random Allocation; Rats; Rats, Sprague-Dawley; Seizures; Tumor Necrosis Factor-alpha | 2015 |
Flavocoxid attenuates gentamicin-induced nephrotoxicity in rats.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Catechin; Dose-Response Relationship, Drug; Drug Combinations; Gentamicins; Male; Organ Culture Techniques; Rats; Rats, Wistar; Urinary Bladder | 2015 |
Antioxidant and anti-inflammatory effects of flavocoxid in high-cholesterol-fed rabbits.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Catechin; Cholesterol, Dietary; Drug Combinations; Hypercholesterolemia; Male; Rabbits; Treatment Outcome | 2015 |
Flavocoxid Protects Against Cadmium-Induced Disruption of the Blood–Testis Barrier and Improves Testicular Damage and Germ Cell Impairment in Mice [corrected].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Biomarkers; Blood-Testis Barrier; Cadherins; Cadmium Poisoning; Catechin; Drug Combinations; Infertility, Male; Lipid Peroxidation; Male; Mice, Inbred C57BL; Occludin; Oxidative Stress; Phosphorylation; Protein Processing, Post-Translational; Seminiferous Tubules; Spermatogenesis; Tight Junctions | 2015 |
The natural dual cyclooxygenase and 5-lipoxygenase inhibitor flavocoxid is protective in EAE through effects on Th1/Th17 differentiation and macrophage/microglia activation.
Topics: Animals; Arachidonate 5-Lipoxygenase; Catechin; Cell Differentiation; Cyclooxygenase Inhibitors; Cytokines; Drug Combinations; Encephalomyelitis, Autoimmune, Experimental; Female; Lipoxygenase Inhibitors; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Microglia; Multiple Sclerosis; Prostaglandin-Endoperoxide Synthases; Th1 Cells; Th17 Cells | 2016 |
Use of a balanced dual cyclooxygenase-1/2 and 5-lypoxygenase inhibitor in experimental colitis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Body Weight; Catechin; CD3 Complex; Celecoxib; Colitis; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Drug Combinations; Eating; Gene Expression Regulation; Hydroxyurea; Leukotriene B4; Lipid Peroxidation; Lipoxygenase Inhibitors; Male; Neutrophil Infiltration; Rats; Rats, Sprague-Dawley; Thromboxane B2; Tumor Necrosis Factor-alpha | 2016 |
Effects of COX1-2/5-LOX blockade in Alzheimer transgenic 3xTg-AD mice.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Catechin; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Drug Combinations; Interleukin-1beta; Leukotriene B4; Lipoxygenase Inhibitors; Male; Maze Learning; Memory; Mice, Transgenic; Neuroprotective Agents; NLR Family, Pyrin Domain-Containing 3 Protein; tau Proteins | 2017 |
Flavocoxid exerts a potent antiviral effect against hepatitis B virus.
Topics: Antiviral Agents; Catechin; Cell Line, Tumor; Cytokines; DNA, Viral; Drug Combinations; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Nitrites; RNA, Messenger; Transfection; Virus Replication | 2018 |
Baicalin in flavocoxid may act against hepatitis B virus via a pro-inflammatory pathway.
Topics: Catechin; Drug Combinations; Flavonoids; Hepatitis B virus | 2018 |
Flavocoxid attenuates airway inflammation in ovalbumin-induced mouse asthma model.
Topics: Animals; Asthma; Biomarkers; Catechin; Disease Models, Animal; Drug Combinations; Inflammation; Lung; Mice; Ovalbumin; Oxidative Stress | 2018 |
The effect of supplementation with Scutellaria baicalensis on hepatic function.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Biomarkers; Catechin; Chemical and Drug Induced Liver Injury; Dietary Supplements; Drug Combinations; Drugs, Chinese Herbal; Female; Follow-Up Studies; Herb-Drug Interactions; Humans; Male; Phytotherapy; Plant Roots; Scutellaria baicalensis; Tea | 2019 |
Comparative safety of flavocoxid vs prescription NSAIDs among osteoarthritis patients.
Topics: Acute Kidney Injury; Adult; Aged; Alveolitis, Extrinsic Allergic; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; Gastrointestinal Hemorrhage; Hospitalization; Humans; Male; Middle Aged; Myocardial Infarction; Osteoarthritis; Polypharmacy; Proportional Hazards Models | 2020 |
Flavocoxid halts both intestinal and extraintestinal alterations in acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Catechin; Colitis, Ulcerative; Drug Combinations; Peroxidase; Rats | 2022 |
Reduction of oxidative stress blunts the NLRP3 inflammatory cascade in LPS stimulated human gingival fibroblasts and oral mucosal epithelial cells.
Topics: Catechin; Drug Combinations; Epithelial Cells; Fibroblasts; Gingiva; Humans; Inflammasomes; Lipopolysaccharides; Mouth Mucosa; Mucositis; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress | 2022 |
Ameliorative effect of flavocoxid on cyclophosphamide-induced cardio and neurotoxicity via targeting the GM-CSF/NF-κB signaling pathway.
Topics: Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Caspase 3; Catechin; Creatine Kinase; Cyclooxygenase 2; Cyclophosphamide; Drug Combinations; Glutathione; Granulocyte-Macrophage Colony-Stimulating Factor; Immunosuppressive Agents; Interleukins; Lactate Dehydrogenases; Macrophage Colony-Stimulating Factor; Malondialdehyde; Mice; Neuroprotective Agents; NF-kappa B; Nitric Oxide; Oxidative Stress; Peroxidases; Signal Transduction; Superoxide Dismutase; Troponin I; Tumor Necrosis Factor-alpha | 2022 |