catechin and isomethyleugenol

catechin has been researched along with isomethyleugenol in 94 studies

Research

Studies (94)

TimeframeStudies, this research(%)All Research%
pre-19905 (5.32)18.7374
1990's11 (11.70)18.2507
2000's41 (43.62)29.6817
2010's32 (34.04)24.3611
2020's5 (5.32)2.80

Authors

AuthorsStudies
Briere, N; Castonguay, A; Pepin, P1
McGrath, RM; Smith, A1
Hackett, AM1
Griffiths, LA; Hackett, AM; Wermeille, M1
Hundt, HK; van der Merwe, PJ1
Griffiths, LA; Hackett, AM; Shaw, IC1
Griffiths, LA; Turin, E; Wermeille, M1
Chen, WF; Ho, CT; Hong, JY; Shi, ST; Smith, TJ; Wang, ZY; Yang, CS1
Inagake, M; Iwashima, A; Kikuoka, N; Kitao, Y; Matsumoto, H; Nakatani, H; Nishimura, H; Oya, K; Takahashi, T; Yamane, T1
Hugouvieux-Cotte-Pattat, N; Nasser, W; Robert-Baudouy, J; Tardy, F1
Da Silva, EL; Piskula, M; Terao, J1
Piskula, MK; Terao, J1
Hara, Y; Matsumoto, N; Nanjo, F; Okushio, K; Suzuki, M2
Donovan, JL; Luthria, DL; Stremple, P; Waterhouse, AL1
Crespy, V; Demigné, C; Manach, C; Morand, C; Régérat, F; Rémésy, C; Texier, O1
Hattori, M; Kakuda, H; Ma, C; Nakamura, N; Qiao, J; Yu, H1
Maeda-Yamamoto, M; Miyase, T; Sano, M; Sunada, Y; Tachibana, H; Yamada, K1
Cai, MX; Conney, AH; Patel, UK; Zhu, BT1
Debnam, ES; Hahn, U; Kuhnle, G; Rice-Evans, C; Schroeter, H; Shenoy, B; Spencer, JP; Srai, SK1
Coddeville, B; Cren-Olivé, C; Déprez, S; Lebrun, S; Rolando, C1
Baba, S; Nakamura, T; Natsume, M; Osakabe, N; Takizawa, T; Terao, J; Yasuda, A1
Hahn, U; Kuhnle, G; Rice-Evans, C; Schroeter, H; Spencer, JP; Srai, SK; Tyrrell, RM1
Dhar, K; Hosny, M; Rosazza, JP1
Crossthwaithe, AJ; Kuhnle, G; Rice-Evans, C; Schroeter, H; Spencer, JP; Williams, RJ1
Baba, S; Muto, Y; Natsume, M; Osakabe, N; Takizawa, T; Terao, J1
Cai, MX; Conney, AH; Lee, AJ; Patel, UK; Zhu, BT1
Cuendet, M; Fong, HH; Hawthorne, ME; Kardono, LB; Kinghorn, AD; Mehta, RG; Pezzuto, JM; Riswan, S; Su, BN1
Fujioka, T; Kouno, I; Mihashi, K; Mine, C; Tanaka, T; Watarumi, S; Zhang, YJ1
Degawa, M; Maeda-Yamamoto, M; Miyase, T; Sano, M; Suzuki, M; Yoshida, R1
Lu, H; Meng, X; Yang, CS1
Spencer, JP1
Chikumoto, T; Inagaki, N; Kawahara, H; Kawakami, T; Kawakami, Y; Kitaura, J; Maeda-Yamamoto, M; Miyase, T; Nagai, H; Sano, M; Tachibana, H1
Conney, AH; Nagai, M; Zhu, BT1
Furuno, K; Kadowaki, M; Ootani, E; Sugihara, N1
Chiu, FL; Lin, JK1
Agusta, A; Maehara, S; Ohashi, K; Shibuya, H; Simanjuntak, P1
Galati, G; Lin, A; O'Brien, PJ; Sultan, AM1
Ardèvol, A; Arola, L; Bladé, C; Fernandez-Larrea, J; García-Ramírez, B; Salvadó, MJ1
Chan, TH; Chen, D; Daniel, KG; Dou, QP; Landis-Piwowar, KR; Wan, SB1
Jiang, Y; Kakuda, Y; Shi, J; Shixian, Q; VanCrey, B1
Chan, TH; Dou, QP; Kuhn, DJ; Landis-Piwowar, KR; Wan, SB; Wiegand, RA1
Schewe, T; Sies, H; Steffen, Y1
Andrews, LG; Berletch, JB; Katiyar, SK; Liu, C; Love, WK; Tollefsbol, TO1
Ando, Y; Chuang, YC; Miyoshi, H; Takahashi, T; Tanaka, H1
Fujimura, Y; Miyase, T; Tachibana, H; Umeda, D; Yamada, K; Yano, S1
Ishiyama, K; Kawano, S; Miyase, T; Nishimura, M; Sano, M; Watanabe, A1
Bai, HW; Shim, JY; Yu, J; Zhu, BT1
Bai, HW; Nagai, M; Shim, JY; Zhu, BT1
Rodríguez-López, JN; Sánchez-del-Campo, L1
Chan, TH; Chen, D; Dou, QP; Huo, C; Landis-Piwowar, KR; Wan, SB1
Dueñas, M; González-Manzano, S; González-Paramás, A; Santos-Buelga, C2
Appeldoorn, MM; Gruppen, H; Hollman, PC; Vincken, JP1
Aihara, Y; Akizawa, T; Furuta, T; Kan, T; Konishi, M; Wakimoto, T; Yoshida, A1
Cheng, HY; Lee, SC; Liu, SY; Wu, SS; Yan, RH1
Dou, QP; Landis-Piwowar, KR1
Dou, QP1
Bishop, SC; Fukui, M; Kang, KS; Wen, Y; Yamabe, N; Zhu, BT1
Hirotsu, K; Miyoshi, H; Tachibana, H; Takahashi, T; Tanaka, H; Yamanouchi, M1
Cao, H; Chen, T; Liu, C; Xiao, J; Xu, X; Yang, F1
Baran, J; Bukowska-Straková, K; Papiez, MA; Wiczkowski, W1
Brown, AL; Dadd, T; Dick, JL; Jackson, KG; Mayes, AE; Miller, RJ; Minihane, AM; Nicol, B1
Agarwal, C; Agarwal, R; Gu, M; Shrestha, SP; Thompson, JA; Wempe, MF1
Esatbeyoglu, T; Homann, T; Kulling, SE; Rawel, HM; Weinert, CH; Wiese, S; Winterhalter, P1
de Roos, B; Duthie, GG; Hollands, W; Kroon, PA; Needs, PW; Ostertag, LM; Saha, S1
Keen, CL; Kwik-Uribe, C; Ottaviani, JI; Schroeter, H1
Kwik-Uribe, C; Oruna-Concha, MJ; Rodriguez-Mateos, A; Spencer, JP; Vidal, A1
Heber, D; Henning, SM; Wang, P2
Anglès, N; Macià, A; Morelló, JR; Motilva, MJ; Ortega, N; Romero, MP; Rubió, L; Serra, A1
Fukui, M; Kang, KS; Wen, Y; Yamabe, N; Zhu, BT1
Imberty, A; Le Bourvellec, C; Renard, CM; Watrelot, AA1
Chen, X; Kai, G; Ni, X; Xiao, J1
Chen, X; Kai, G; Xiao, J; Yamamoto, K1
Abe, Y; Kanda, T; Kirita, M; Maeda-Yamamoto, M; Miyata, S; Tagashira, M; Tanaka, Y2
Buer, J; Geffers, R; Kehrmann, J; Probst-Kepper, M; Steinmann, J; Tatura, R; Zeschnigk, M1
Kanda, T; Kirita, M; Maeda-Yamamoto, M; Tagashira, M; Tanaka, Y1
Cifuentes-Gomez, T; Gonzalez-Salvador, I; Heiss, C; Kelm, M; Ottaviani, JI; Rodriguez-Mateos, A; Schroeter, H; Spencer, JP1
Chow, LM; Duan, LX; Hu, X; Jiang, T; Li, XM; Liu, T; Liu, Z; Wan, SB; Wang, BC; Wong, IL; Yuan, J; Zhang, XY1
Aihara, Y; Asakawa, T; Furuta, T; Hamashima, Y; Hirose, Y; Inai, M; Kan, T; Kawabe, Y; Manabe, T; Sakurada, A; Wakimoto, T; Yoshida, A1
Chen, Q; Huang, J; Lin, H; Lin, Y; Liu, Z; Wang, K; Yu, S1
Chen, K; Chen, L; Jia, Q; Li, Y; Wang, H; Wang, T; Yuan, P1
Borges, G; Crozier, A; van der Hooft, JJJ1
Dai, S; Lu, J; Shang, Z; Wang, F; Wu, X; Zhang, J1
Jankun, J; Matthews-Brzozowska, T; Matthews-Kozanecka, M; Skrzypczak-Jankun, E; Wyganowska-Świątkowska, M1
Gao, HY; He, XW; Shi, X; Yan, W; Yang, W1
Cai, H; Hong, S; Liu, S; Wang, S1
Balcerczyk, A; Biesiekierska, M; Ciesielski, O1
Sun, Z; Wang, J; Xie, B1
Chow, LMC; Li, FX; Li, P; Liu, Z; Sun, W; Wan, SB; Wang, BC; Wang, XK; Wong, ILK1
Fujimura, Y; Hamagami, H; Horie, F; Kumazoe, M; Tachibana, H; Takamatsu, K; Tanaka, H; Yoshitomi, R1
Bourgeois, B; Habacher, H; Khanna, Y; Lenard, AJ; Madl, T; Madreiter-Sokolowski, C; Zhou, Q1

Reviews

8 review(s) available for catechin and isomethyleugenol

ArticleYear
The metabolism of flavonoid compounds in mammals.
    Progress in clinical and biological research, 1986, Volume: 213

    Topics: Animals; Bile; Catechin; Enterohepatic Circulation; Flavonoids; Glucuronates; Glycosides; Humans; Hydrolysis; Liver; Methylation; Oxidation-Reduction; Sulfates; Tissue Distribution

1986
Metabolism of tea flavonoids in the gastrointestinal tract.
    The Journal of nutrition, 2003, Volume: 133, Issue:10

    Topics: Biological Availability; Catechin; Colon; Digestive System; Flavonoids; Gastric Mucosa; Humans; Ileum; Intestinal Absorption; Jejunum; Methylation; Saliva; Tea

2003
Green tea extract thermogenesis-induced weight loss by epigallocatechin gallate inhibition of catechol-O-methyltransferase.
    Journal of medicinal food, 2006,Winter, Volume: 9, Issue:4

    Topics: Adipose Tissue, Brown; Animals; Camellia sinensis; Catechin; Catechol O-Methyltransferase Inhibitors; Enzyme Inhibitors; Male; Methylation; Norepinephrine; Plant Extracts; Rats; Thermogenesis; Weight Loss

2006
Green tea polyphenols as a natural tumour cell proteasome inhibitor.
    Inflammopharmacology, 2008, Volume: 16, Issue:5

    Topics: Anticarcinogenic Agents; Catechin; Methylation; Proteasome Inhibitors; Tea; Ubiquitin

2008
Polyphenols: biological activities, molecular targets, and the effect of methylation.
    Current molecular pharmacology, 2008, Volume: 1, Issue:3

    Topics: Anticarcinogenic Agents; Catechin; Flavonoids; Humans; Methylation; Phenols; Polyphenols; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Ubiquitin

2008
A review on structure-activity relationship of dietary polyphenols inhibiting α-amylase.
    Critical reviews in food science and nutrition, 2013, Volume: 53, Issue:5

    Topics: alpha-Amylases; Anthocyanins; Catechin; Coumaric Acids; Galactosides; Glucosides; Glycosylation; Humans; Hydrolyzable Tannins; Hydroxylation; Methylation; Molecular Structure; Polyphenols; Proanthocyanidins; Structure-Activity Relationship

2013
Advance in dietary polyphenols as α-glucosidases inhibitors: a review on structure-activity relationship aspect.
    Critical reviews in food science and nutrition, 2013, Volume: 53, Issue:8

    Topics: alpha-Glucosidases; Anthocyanins; Catechin; Chalcone; Coumaric Acids; Diet; Glycoside Hydrolase Inhibitors; Glycosylation; Humans; Hydrogenation; Hydroxylation; Methylation; Polyphenols; Proanthocyanidins; Stilbenes; Structure-Activity Relationship; Tannins

2013
Can EGCG Alleviate Symptoms of Down Syndrome by Altering Proteolytic Activity?
    International journal of molecular sciences, 2018, Jan-15, Volume: 19, Issue:1

    Topics: Animals; Biomarkers; Catechin; Down Syndrome; Humans; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Methylation; Proteolysis; Signal Transduction; Tissue Plasminogen Activator

2018

Trials

6 trial(s) available for catechin and isomethyleugenol

ArticleYear
Bioavailability of (-)-epicatechin upon intake of chocolate and cocoa in human volunteers.
    Free radical research, 2000, Volume: 33, Issue:5

    Topics: Adult; Biological Availability; Cacao; Catechin; Chromatography, High Pressure Liquid; Chromatography, Liquid; Humans; Intestinal Absorption; Male; Mass Spectrometry; Methylation

2000
A preliminary investigation of the impact of catechol-O-methyltransferase genotype on the absorption and metabolism of green tea catechins.
    European journal of nutrition, 2012, Volume: 51, Issue:1

    Topics: Amino Acid Substitution; Catechin; Catechol O-Methyltransferase; Dietary Supplements; Female; Genetic Association Studies; Homozygote; Humans; Intestinal Absorption; Kinetics; Male; Methylation; Middle Aged; Phenols; Pilot Projects; Plant Extracts; Polymorphism, Single Nucleotide; Tea

2012
Human O-sulfated metabolites of (-)-epicatechin and methyl-(-)-epicatechin are poor substrates for commercial aryl-sulfatases: implications for studies concerned with quantifying epicatechin bioavailability.
    Pharmacological research, 2012, Volume: 65, Issue:6

    Topics: Administration, Oral; Arylsulfatases; Biological Availability; Biotransformation; Catechin; Chromatography, Liquid; Cross-Over Studies; England; Female; Glucuronidase; Humans; Hydrogen-Ion Concentration; Hydrolysis; Male; Methylation; Reproducibility of Results; Substrate Specificity; Sulfuric Acid Esters; Tandem Mass Spectrometry; Time Factors

2012
Intake of dietary procyanidins does not contribute to the pool of circulating flavanols in humans.
    The American journal of clinical nutrition, 2012, Volume: 95, Issue:4

    Topics: Adolescent; Adult; Analytic Sample Preparation Methods; Biflavonoids; Catechin; Cross-Over Studies; Diet; Double-Blind Method; Flavonoids; Glucuronides; Humans; Lactones; Male; Methylation; Molecular Weight; Polymerization; Postprandial Period; Proanthocyanidins; Young Adult

2012
Influence of sugar type on the bioavailability of cocoa flavanols.
    The British journal of nutrition, 2012, Dec-28, Volume: 108, Issue:12

    Topics: Adult; Biological Availability; Cacao; Catechin; Cross-Over Studies; Double-Blind Method; Female; Flavonoids; Humans; Male; Maltose; Methylation; Sucrose; Sugar Alcohols; Sweetening Agents

2012
Influence of age on the absorption, metabolism, and excretion of cocoa flavanols in healthy subjects.
    Molecular nutrition & food research, 2015, Volume: 59, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Beverages; Cacao; Catechin; Cross-Over Studies; Flavonoids; Glucuronides; Half-Life; Humans; Intestinal Absorption; Kinetics; Lactones; Male; Methylation; Patient Dropouts; Renal Elimination; Stereoisomerism; Sulfuric Acid Esters; Young Adult

2015

Other Studies

80 other study(ies) available for catechin and isomethyleugenol

ArticleYear
Modulation of 4-(methylnitrosamino)-1-(3-pyridyl)-1 butanone demethylation and denitrosation by rat liver microsomes.
    Cancer letters, 1991, Jul-26, Volume: 59, Issue:1

    Topics: Animals; Carcinogens; Catechin; Dimethylnitrosamine; Enzyme Induction; Formaldehyde; Kinetics; Male; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Nitrates; Nitrogen Dioxide; Nitrosamines; Nitrosation; Rats; Rats, Inbred F344

1991
The isolation of large molecular mass procyanidins from grain sorghum and their interaction with [14C]methyl bovine serum albumins.
    The International journal of biochemistry, 1990, Volume: 22, Issue:12

    Topics: Animals; Biflavonoids; Binding, Competitive; Carbon Radioisotopes; Catechin; Cattle; Chromatography, Gel; Edible Grain; Methylation; Molecular Weight; Osmolar Concentration; Proanthocyanidins; Serum Albumin, Bovine

1990
The quantitative disposition of 3-O-methyl-(+)-[U-14C]catechin in man following oral administration.
    Xenobiotica; the fate of foreign compounds in biological systems, 1985, Volume: 15, Issue:11

    Topics: Administration, Oral; Adult; Benzopyrans; Catechin; Glucuronates; Glucuronic Acid; Humans; Male; Metabolic Clearance Rate; Methylation; Species Specificity; Sulfates

1985
Metabolism of (+)-catechin and some of its C-6 and C-8 substituted derivatives in the isolated perfused pig liver.
    Xenobiotica; the fate of foreign compounds in biological systems, 1984, Volume: 14, Issue:10

    Topics: Animals; Benzopyrans; Bile; Catechin; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Hydrolysis; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylation; Perfusion; Structure-Activity Relationship; Swine

1984
3'-O-methyl-(+)-catechin glucuronide and 3'-O-methyl-(+)-catechin sulphate: new urinary metabolites of (+)-catechin in the rat and the marmoset.
    Experientia, 1982, May-15, Volume: 38, Issue:5

    Topics: Animals; Benzopyrans; Callitrichinae; Catechin; Glucuronates; Kinetics; Male; Methylation; Rats; Rats, Inbred Strains; Species Specificity; Sulfates

1982
Identification of the major urinary metabolites of (+)-catechin and 3-O-methyl-(+)-catechin in man.
    European journal of drug metabolism and pharmacokinetics, 1983, Volume: 8, Issue:1

    Topics: Benzopyrans; Biotransformation; Catechin; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Magnetic Resonance Spectroscopy; Methylation

1983
Effects of green tea and black tea on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation, DNA methylation, and lung tumorigenesis in A/J mice.
    Cancer research, 1994, Sep-01, Volume: 54, Issue:17

    Topics: Animals; Beverages; Carcinogens; Catechin; DNA; Female; Flavonoids; Lung; Lung Neoplasms; Methylation; Mice; Microsomes; Nitrosamines; Pyridines; Tea

1994
Inhibition of 1,2-dimethylhydrazine-induced oxidative DNA damage by green tea extract in rat.
    Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:11

    Topics: 1,2-Dimethylhydrazine; 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Animals; Anticarcinogenic Agents; Azoxymethane; Biotransformation; Catechin; Colon; Deoxyguanosine; Diazonium Compounds; Dimethylhydrazines; DNA; DNA Damage; Free Radical Scavengers; Injections, Subcutaneous; Intestinal Mucosa; Kidney; Liver; Male; Methylation; Methylazoxymethanol Acetate; Oxidation-Reduction; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Tea

1995
Comparative analysis of the five major Erwinia chrysanthemi pectate lyases: enzyme characteristics and potential inhibitors.
    Journal of bacteriology, 1997, Volume: 179, Issue:8

    Topics: Calcium Chloride; Catechin; Cations, Divalent; Dickeya chrysanthemi; Enzyme Inhibitors; Escherichia coli; Hot Temperature; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Methylation; Pectins; Polysaccharide-Lyases; Recombinant Fusion Proteins; Salicylates; Salicylic Acid; Substrate Specificity

1997
Enhancement of antioxidative ability of rat plasma by oral administration of (-)-epicatechin.
    Free radical biology & medicine, 1998, Volume: 24, Issue:7-8

    Topics: Administration, Oral; Amidines; Animals; Antioxidants; Catechin; Cholesterol Esters; Copper Sulfate; Free Radicals; In Vitro Techniques; Lipid Peroxidation; Male; Methylation; Oxidants; Plasma; Rats; Rats, Wistar; Vitamin E

1998
Accumulation of (-)-epicatechin metabolites in rat plasma after oral administration and distribution of conjugation enzymes in rat tissues.
    The Journal of nutrition, 1998, Volume: 128, Issue:7

    Topics: Animals; Arylsulfotransferase; Catechin; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Glucuronates; Glucuronosyltransferase; Hydrolysis; Intestinal Absorption; Intestinal Mucosa; Kidney; Liver; Male; Methylation; Rats; Rats, Wistar; Sulfates

1998
Identification of (-)-epicatechin metabolites and their metabolic fate in the rat.
    Drug metabolism and disposition: the biological fate of chemicals, 1999, Volume: 27, Issue:2

    Topics: Administration, Oral; Animals; Bile; Catechin; Chromatography, High Pressure Liquid; Glucuronates; Magnetic Resonance Spectroscopy; Male; Methylation; Rats; Rats, Wistar; Spectrometry, Mass, Fast Atom Bombardment

1999
Methylation of tea catechins by rat liver homogenates.
    Bioscience, biotechnology, and biochemistry, 1999, Volume: 63, Issue:2

    Topics: Animals; Catechin; Chromatography, High Pressure Liquid; Flavonoids; Liver; Magnetic Resonance Spectroscopy; Male; Methylation; Rats; Rats, Wistar; S-Adenosylmethionine; Spectrometry, Mass, Fast Atom Bombardment; Tea

1999
Analysis of (+)-catechin, (-)-epicatechin and their 3'- and 4'-O-methylated analogs. A comparison of sensitive methods.
    Journal of chromatography. B, Biomedical sciences and applications, 1999, Apr-16, Volume: 726, Issue:1-2

    Topics: Catechin; Chromatography, High Pressure Liquid; Electrochemistry; Humans; Magnetic Resonance Spectroscopy; Methylation; Reference Standards; Sensitivity and Specificity; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

1999
Comparison of the bioavailability of quercetin and catechin in rats.
    Free radical biology & medicine, 1999, Volume: 27, Issue:11-12

    Topics: Animals; Biological Availability; Catechin; Chromatography, High Pressure Liquid; Diet; Glucuronides; Liver; Male; Methylation; Quercetin; Rats; Rats, Wistar; Sulfates

1999
Inhibitory effects on HIV-1 protease of constituents from the wood of Xanthoceras sorbifolia.
    Journal of natural products, 2000, Volume: 63, Issue:2

    Topics: Anthocyanins; Catechin; Crystallography, X-Ray; HIV Protease; HIV Protease Inhibitors; Humans; Magnetic Resonance Spectroscopy; Methylation; Plants, Medicinal; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared; Triterpenes; Wood

2000
Identification of a methylated tea catechin as an inhibitor of degranulation in human basophilic KU812 cells.
    Bioscience, biotechnology, and biochemistry, 2000, Volume: 64, Issue:2

    Topics: Basophils; Catechin; Cell Degranulation; Cell Line; Humans; Methylation

2000
O-Methylation of tea polyphenols catalyzed by human placental cytosolic catechol-O-methyltransferase.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:9

    Topics: Catechin; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Cytosol; Dose-Response Relationship, Drug; Female; Flavonoids; Humans; Hydrogen-Ion Concentration; Kinetics; Mass Spectrometry; Methylation; Phenols; Placenta; Polymers; Pregnancy; S-Adenosylhomocysteine; Tea

2000
Epicatechin and catechin are O-methylated and glucuronidated in the small intestine.
    Biochemical and biophysical research communications, 2000, Oct-22, Volume: 277, Issue:2

    Topics: Animals; Biological Transport; Catechin; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Glucuronides; Ileum; Intestine, Small; Jejunum; Mass Spectrometry; Methylation; Rats

2000
Characterization of methylation site of monomethylflavan-3-ols by liquid chromatography/electrospray ionization tandem mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2000, Volume: 14, Issue:23

    Topics: Catechin; Chromatography, Liquid; Methylation; Spectrometry, Mass, Electrospray Ionization

2000
Epicatechin and its in vivo metabolite, 3'-O-methyl epicatechin, protect human fibroblasts from oxidative-stress-induced cell death involving caspase-3 activation.
    The Biochemical journal, 2001, Mar-15, Volume: 354, Issue:Pt 3

    Topics: Antioxidants; Apoptosis; Caspase 3; Caspases; Catechin; Cells, Cultured; Fibroblasts; Humans; Hydrogen Peroxide; Lipoproteins, LDL; Methylation; Mitochondria; Oxidative Stress

2001
Hydroxylations and methylations of quercetin, fisetin, and catechin by Streptomyces griseus.
    Journal of natural products, 2001, Volume: 64, Issue:4

    Topics: Catechin; Flavonoids; Flavonols; Hydroxylation; Methylation; Quercetin; Spectrum Analysis; Streptomyces

2001
Contrasting influences of glucuronidation and O-methylation of epicatechin on hydrogen peroxide-induced cell death in neurons and fibroblasts.
    Free radical biology & medicine, 2001, Nov-01, Volume: 31, Issue:9

    Topics: Animals; Caspase 3; Caspases; Catechin; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Dermis; Fibroblasts; Flavonoids; Glucuronides; Humans; Hydrogen Peroxide; Methylation; Mice; Neurons

2001
In vivo comparison of the bioavailability of (+)-catechin, (-)-epicatechin and their mixture in orally administered rats.
    The Journal of nutrition, 2001, Volume: 131, Issue:11

    Topics: Administration, Oral; Animals; Area Under Curve; Biological Availability; Catechin; Chromatography, High Pressure Liquid; Chromatography, Liquid; Intestinal Absorption; Male; Methylation; Rats; Rats, Sprague-Dawley; Stereoisomerism

2001
Rapid conversion of tea catechins to monomethylated products by rat liver cytosolic catechol-O-methyltransferase.
    Xenobiotica; the fate of foreign compounds in biological systems, 2001, Volume: 31, Issue:12

    Topics: Animals; Catechin; Catechol O-Methyltransferase; Cytosol; Female; Flavonoids; Hydrogen-Ion Concentration; Kinetics; Liver; Mass Spectrometry; Methylation; Phenols; Polymers; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; Tea

2001
Constituents of the bark and twigs of Artocarpus dadah with cyclooxygenase inhibitory activity.
    Journal of natural products, 2002, Volume: 65, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylation; Animals; Benzofurans; Breast; Catechin; Cell Transformation, Neoplastic; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Indonesia; Isoenzymes; Membrane Proteins; Methylation; Mice; Mice, Inbred BALB C; Molecular Structure; Moraceae; Nuclear Magnetic Resonance, Biomolecular; Organ Culture Techniques; Plant Bark; Plant Extracts; Plant Shoots; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Stilbenes

2002
Accumulation of epigallocatechin quinone dimers during tea fermentation and formation of theasinensins.
    Journal of natural products, 2002, Volume: 65, Issue:11

    Topics: Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Fermentation; Hydrolysis; Japan; Methylation; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Phenazines; Plant Leaves; Plants, Medicinal; Quinones; Tea

2002
Epimerization of tea catechins and O-methylated derivatives of (-)-epigallocatechin-3-O-gallate: relationship between epimerization and chemical structure.
    Journal of agricultural and food chemistry, 2003, Jan-15, Volume: 51, Issue:2

    Topics: Catechin; Hot Temperature; Hydrogen-Ion Concentration; Methylation; Molecular Structure; Plant Extracts; Plant Leaves; Solutions; Stereoisomerism; Tea; Water

2003
Enzymology of methylation of tea catechins and inhibition of catechol-O-methyltransferase by (-)-epigallocatechin gallate.
    Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:5

    Topics: Animals; Catechin; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cytosol; Enzyme Inhibitors; Female; Gas Chromatography-Mass Spectrometry; Glucuronides; Intestinal Mucosa; Intestines; Liver; Male; Methylation; Mice; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Species Specificity; Swine; Tea

2003
O-methylated catechins from tea leaves inhibit multiple protein kinases in mast cells.
    Journal of immunology (Baltimore, Md. : 1950), 2004, Apr-01, Volume: 172, Issue:7

    Topics: Animals; Anti-Allergic Agents; Catechin; Enzyme Activation; Enzyme Inhibitors; Mast Cells; Methylation; Mice; Mice, Inbred CBA; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Passive Cutaneous Anaphylaxis; Plant Leaves; Protein Kinase C; Protein Kinase C beta; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Signal Transduction; Tea

2004
Strong inhibitory effects of common tea catechins and bioflavonoids on the O-methylation of catechol estrogens catalyzed by human liver cytosolic catechol-O-methyltransferase.
    Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:5

    Topics: Catalysis; Catechin; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrogens, Catechol; Flavonoids; Humans; Liver; Methylation; Plant Extracts; Tea

2004
Inhibitory effects of catechin gallates on o-methyltranslation of protocatechuic acid in rat liver cytosolic preparations and cultured hepatocytes.
    Biological & pharmaceutical bulletin, 2005, Volume: 28, Issue:8

    Topics: Animals; Catechin; Catechol O-Methyltransferase; Cells, Cultured; Chromatography, High Pressure Liquid; Cytosol; Hepatocytes; Hydroxybenzoates; Liver; Male; Methylation; Rats; Rats, Wistar

2005
HPLC analysis of naturally occurring methylated catechins, 3' '- and 4' '-methyl-epigallocatechin gallate, in various fresh tea leaves and commercial teas and their potent inhibitory effects on inducible nitric oxide synthase in macrophages.
    Journal of agricultural and food chemistry, 2005, Sep-07, Volume: 53, Issue:18

    Topics: Camellia sinensis; Catechin; Fermentation; Methylation; Plant Leaves; Seasons; Taiwan

2005
Stereoselective oxidation at C-4 of flavans by the endophytic fungus Diaporthe sp. isolated from a tea plant.
    Chemical & pharmaceutical bulletin, 2005, Volume: 53, Issue:12

    Topics: Ascomycota; Camellia; Catechin; Chromatography, High Pressure Liquid; DNA, Fungal; Flavins; Methylation; Oxidation-Reduction; Oxygen; Reverse Transcriptase Polymerase Chain Reaction; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Stereoisomerism

2005
Cellular and in vivo hepatotoxicity caused by green tea phenolic acids and catechins.
    Free radical biology & medicine, 2006, Feb-15, Volume: 40, Issue:4

    Topics: Alanine Transaminase; Animals; Antioxidants; Catechin; Gallic Acid; Glutathione; Hydroxybenzoates; Iron; Liver; Male; Mass Spectrometry; Methylation; Mice; NAD(P)H Dehydrogenase (Quinone); Rats; Rats, Sprague-Dawley; Tea

2006
Tetramethylated dimeric procyanidins are detected in rat plasma and liver early after oral administration of synthetic oligomeric procyanidins.
    Journal of agricultural and food chemistry, 2006, Apr-05, Volume: 54, Issue:7

    Topics: Absorption; Animals; Biflavonoids; Catechin; Chromatography, High Pressure Liquid; Dimerization; Hydrogen-Ion Concentration; Liver; Male; Mass Spectrometry; Methylation; Proanthocyanidins; Rats; Rats, Wistar; Structure-Activity Relationship

2006
Methylation of green tea polyphenols affects their binding to and inhibitory poses of the proteasome beta5 subunit.
    International journal of molecular medicine, 2006, Volume: 18, Issue:4

    Topics: Catechin; Chymotrypsin; Dose-Response Relationship, Drug; Flavonoids; Methylation; Models, Molecular; Molecular Conformation; Phenols; Polyphenols; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Protein Subunits; Tea

2006
Methylation suppresses the proteasome-inhibitory function of green tea polyphenols.
    Journal of cellular physiology, 2007, Volume: 213, Issue:1

    Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Death; Flavonoids; Humans; Jurkat Cells; Methylation; Phenols; Polyphenols; Protease Inhibitors; Proteasome Inhibitors; Tea

2007
(-)-Epicatechin elevates nitric oxide in endothelial cells via inhibition of NADPH oxidase.
    Biochemical and biophysical research communications, 2007, Aug-03, Volume: 359, Issue:3

    Topics: Acetophenones; Angiotensin II; Catechin; Cells, Cultured; Cyclic GMP; Endothelial Cells; Enzyme Inhibitors; Humans; Methylation; Molecular Structure; NADPH Oxidases; Nitric Oxide; Signal Transduction; Umbilical Cord

2007
Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG.
    Journal of cellular biochemistry, 2008, Feb-01, Volume: 103, Issue:2

    Topics: Adenocarcinoma; Apoptosis; Breast Neoplasms; Catechin; Cell Division; Cell Line, Tumor; DNA Methylation; E2F1 Transcription Factor; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histones; HL-60 Cells; Humans; Lysine; Male; Methylation; Neoplasm Proteins; Promoter Regions, Genetic; Protein Processing, Post-Translational; RNA, Messenger; RNA, Neoplasm; Telomerase

2008
Solid-phase synthesis of epigallocatechin gallate derivatives.
    Angewandte Chemie (International ed. in English), 2007, Volume: 46, Issue:31

    Topics: Anticarcinogenic Agents; Antioxidants; Catechin; Methylation

2007
Relationship between the biological activities of methylated derivatives of (-)-epigallocatechin-3-O-gallate (EGCG) and their cell surface binding activities.
    Journal of agricultural and food chemistry, 2007, Aug-22, Volume: 55, Issue:17

    Topics: Basophils; Catechin; Cell Line; Cell Membrane; Humans; Methylation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Structure-Activity Relationship

2007
Determination of theaflavins including methylated theaflavins in black tea leaves by solid-phase extraction and HPLC analysis.
    Journal of agricultural and food chemistry, 2007, Sep-05, Volume: 55, Issue:18

    Topics: Biflavonoids; Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Ethanol; Fermentation; Methylation; Plant Leaves

2007
Biochemical and molecular modeling studies of the O-methylation of various endogenous and exogenous catechol substrates catalyzed by recombinant human soluble and membrane-bound catechol-O-methyltransferases.
    Chemical research in toxicology, 2007, Volume: 20, Issue:10

    Topics: Catechin; Catechol O-Methyltransferase; Catecholamines; Catechols; Computer Simulation; Estrogens, Catechol; Flavonoids; Humans; Membrane Proteins; Methylation; Models, Biological; Models, Molecular; Protein Binding; Recombinant Proteins

2007
Molecular modelling study of the mechanism of high-potency inhibition of human catechol-O-methyltransferase by (-)-epigallocatechin-3-O-gallate.
    Xenobiotica; the fate of foreign compounds in biological systems, 2008, Volume: 38, Issue:2

    Topics: Animals; Catechin; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Kinetics; Methylation; Models, Molecular; Rats; Swine

2008
Targeting the methionine cycle for melanoma therapy with 3-O-(3,4,5-trimethoxybenzoyl)-(-)-epicatechin.
    International journal of cancer, 2008, Nov-15, Volume: 123, Issue:10

    Topics: Adenosine; Animals; Antineoplastic Agents; Apoptosis; Base Sequence; Blotting, Western; Caspase 3; Catechin; Cell Line, Tumor; DNA Primers; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Melanoma; Methionine; Methylation; Mice; Microscopy, Confocal; Microscopy, Electron; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction

2008
Preparation and characterization of catechin sulfates, glucuronides, and methylethers with metabolic interest.
    Journal of agricultural and food chemistry, 2009, Feb-25, Volume: 57, Issue:4

    Topics: Catechin; Chromatography, High Pressure Liquid; Ethers; Glucuronides; Methylation; Spectrometry, Mass, Electrospray Ionization; Sulfuric Acid Esters

2009
Antioxidant evaluation of O-methylated metabolites of catechin, epicatechin and quercetin.
    Journal of pharmaceutical and biomedical analysis, 2010, Jan-20, Volume: 51, Issue:2

    Topics: Antioxidants; Catechin; Ferric Compounds; Fluorescence Recovery After Photobleaching; Free Radical Scavengers; Hydrogen-Ion Concentration; Methylation; Molecular Structure; Oxidation-Reduction; Quercetin; Reference Standards

2010
Procyanidin dimers A1, A2, and B2 are absorbed without conjugation or methylation from the small intestine of rats.
    The Journal of nutrition, 2009, Volume: 139, Issue:8

    Topics: Animals; Biflavonoids; Catechin; Dimerization; Intestinal Absorption; Intestine, Small; Metabolic Detoxication, Phase II; Methylation; Perfusion; Polymers; Proanthocyanidins; Rats

2009
Regioselective synthesis of methylated epigallocatechin gallate via nitrobenzenesulfonyl (Ns) protecting group.
    Bioorganic & medicinal chemistry letters, 2009, Aug-01, Volume: 19, Issue:15

    Topics: Animals; Catechin; Chemistry, Organic; Chemistry, Pharmaceutical; Drug Design; Humans; Inhibitory Concentration 50; Matrix Metalloproteinase 1; Matrix Metalloproteinase 7; Methylation; Mice; Models, Chemical; Recombinant Proteins; Stereoisomerism; Tea

2009
Screen and genetic assessment of tea germplasms with elevated methylated catechin, (-)-epigallocatechin-3-O-(3-O-methyl)gallate.
    Journal of agricultural and food chemistry, 2009, Oct-14, Volume: 57, Issue:19

    Topics: Breeding; Caffeine; Camellia sinensis; Catechin; Methylation; Phylogeny; Plant Leaves; Species Specificity; Taiwan

2009
Molecular mechanisms of green tea polyphenols.
    Nutrition and cancer, 2009, Volume: 61, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis; Biological Availability; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Female; Flavonoids; Humans; Male; Methylation; Mice; Phenols; Polyphenols; Prodrugs; Proteasome Inhibitors; Rats; Tea; Ubiquitinated Proteins

2009
Dual beneficial effects of (-)-epigallocatechin-3-gallate on levodopa methylation and hippocampal neurodegeneration: in vitro and in vivo studies.
    PloS one, 2010, Aug-05, Volume: 5, Issue:8

    Topics: Animals; Biological Products; Catechin; Catechol O-Methyltransferase Inhibitors; Cell Death; Cell Line; Enzyme Inhibitors; Hippocampus; Humans; Kainic Acid; Levodopa; Male; Methylation; Mice; Neurons; Oxidative Stress; Rats; Rats, Sprague-Dawley

2010
Solid-phase synthesis of a combinatorial methylated (±)-epigallocatechin gallate library and the growth-inhibitory effects of these compounds on melanoma B16 cells.
    Chemistry, an Asian journal, 2010, Oct-04, Volume: 5, Issue:10

    Topics: Animals; Antineoplastic Agents; Catechin; Cell Line, Tumor; Combinatorial Chemistry Techniques; Hydrogenation; Melanoma, Experimental; Methylation; Mice; Small Molecule Libraries

2010
Molecular property-binding affinity relationship of flavonoids for common rat plasma proteins in vitro.
    Biochimie, 2011, Volume: 93, Issue:2

    Topics: Animals; Apigenin; Blood Proteins; Catechin; Cattle; Chromatography, Reverse-Phase; Flavonoids; Glycosylation; Humans; Hydroxylation; Isomerism; Methylation; Protein Binding; Rats; Structure-Activity Relationship; Surface Properties

2011
Antileukemic action of (-)-epicatechin in the spleen of rats with acute myeloid leukemia.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:12

    Topics: Animals; Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; Body Weight; Catechin; Cell Line; Comet Assay; DNA Damage; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Leukemia, Myeloid, Acute; Methylation; Organ Size; Oxidation-Reduction; Phosphatidylserines; Purines; Rats; Spleen

2010
Glucuronidation and methylation of procyanidin dimers b2 and 3,3″-di-o-galloyl-b2 and corresponding monomers epicatechin and 3-o-galloyl-epicatechin in mouse liver.
    Pharmaceutical research, 2012, Volume: 29, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biflavonoids; Catechin; Dimerization; Glucuronides; Grape Seed Extract; Male; Methylation; Mice; Mice, Inbred C57BL; Microsomes, Liver; Proanthocyanidins

2012
Methylation of catechins and procyanidins by rat and human catechol-O-methyltransferase: metabolite profiling and molecular modeling studies.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Animals; Catechin; Catechol O-Methyltransferase; Computer Simulation; Cytosol; Female; Humans; Liver; Methylation; Models, Molecular; Molecular Structure; Placenta; Pregnancy; Pregnancy Proteins; Proanthocyanidins; Rats; Rats, Wistar; S-Adenosylmethionine; Species Specificity; Substrate Specificity

2012
Quercetin increased bioavailability and decreased methylation of green tea polyphenols in vitro and in vivo.
    Food & function, 2012, Volume: 3, Issue:6

    Topics: Animals; Biological Availability; Catechin; Catechol O-Methyltransferase; Cell Line, Tumor; Down-Regulation; Humans; Male; Methylation; Mice; Mice, SCID; Neoplasms; Polyphenols; Quercetin; Tea; Up-Regulation

2012
Quercetin increased the antiproliferative activity of green tea polyphenol (-)-epigallocatechin gallate in prostate cancer cells.
    Nutrition and cancer, 2012, Volume: 64, Issue:4

    Topics: Androgens; Anticarcinogenic Agents; Catechin; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Humans; Male; Methylation; Prostatic Neoplasms; Quercetin; Tea

2012
Distribution of procyanidins and their metabolites in rat plasma and tissues in relation to ingestion of procyanidin-enriched or procyanidin-rich cocoa creams.
    European journal of nutrition, 2013, Volume: 52, Issue:3

    Topics: Animals; Antioxidants; Cacao; Catechin; Corylus; Diet; Food, Fortified; Glucuronides; Kidney; Kinetics; Liver; Male; Methylation; Nuts; Plant Extracts; Proanthocyanidins; Rats; Rats, Wistar; Seeds; Spain; Surface Properties; Tissue Distribution

2013
Beneficial effects of natural phenolics on levodopa methylation and oxidative neurodegeneration.
    Brain research, 2013, Feb-25, Volume: 1497

    Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Antiparkinson Agents; Carbidopa; Catechin; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Disease Models, Animal; Excitatory Amino Acid Agonists; Fluoresceins; Glial Fibrillary Acidic Protein; Hippocampus; Hydroxybenzoates; In Vitro Techniques; Kainic Acid; Levodopa; Male; Methylation; Mice; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Reserpine; Time Factors; Tyrosine

2013
Interactions between pectic compounds and procyanidins are influenced by methylation degree and chain length.
    Biomacromolecules, 2013, Mar-11, Volume: 14, Issue:3

    Topics: Catechin; Citrus; Flavonoids; Food Handling; Fruit; Hexuronic Acids; Malus; Methylation; Pectins; Polymerization; Proanthocyanidins

2013
O-methylated theaflavins suppress the intracellular accumulation of triglycerides from terminally differentiated human visceral adipocytes.
    Journal of agricultural and food chemistry, 2013, Dec-26, Volume: 61, Issue:51

    Topics: Adipocytes; Biflavonoids; Catechin; Cell Differentiation; Down-Regulation; Humans; Intra-Abdominal Fat; Methylation; Triglycerides

2013
Impact of 5-aza-2'-deoxycytidine and epigallocatechin-3-gallate for induction of human regulatory T cells.
    Immunology, 2014, Volume: 142, Issue:3

    Topics: Azacitidine; Catechin; Decitabine; Forkhead Transcription Factors; Humans; Male; Methylation; Oligonucleotide Array Sequence Analysis; T-Lymphocytes, Regulatory

2014
Metabolic stability and inhibitory effect of O-methylated theaflavins on H2O2-induced oxidative damage in human HepG2 cells.
    Bioscience, biotechnology, and biochemistry, 2014, Volume: 78, Issue:7

    Topics: Biflavonoids; Catechin; Drug Stability; Hep G2 Cells; Humans; Hydrogen Peroxide; Methylation; Oxidative Stress; Oxygen

2014
Cloning and characterization of a novel O-methyltransferase from Flammulina velutipes that catalyzes methylation of pyrocatechol and pyrogallol structures in polyphenols.
    Bioscience, biotechnology, and biochemistry, 2015, Volume: 79, Issue:7

    Topics: Amino Acid Sequence; Catechin; Catechol O-Methyltransferase; Catechols; Cloning, Molecular; Escherichia coli; Flammulina; Fungal Proteins; Gallic Acid; Methylation; Methyltransferases; Molecular Sequence Data; Molecular Structure; Polyphenols; Pyrogallol; Recombinant Proteins; Substrate Specificity

2015
Potent and Nontoxic Chemosensitizer of P-Glycoprotein-Mediated Multidrug Resistance in Cancer: Synthesis and Evaluation of Methylated Epigallocatechin, Gallocatechin, and Dihydromyricetin Derivatives.
    Journal of medicinal chemistry, 2015, Jun-11, Volume: 58, Issue:11

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Catechin; Cell Proliferation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavonols; Humans; Methylation; Models, Molecular; Molecular Structure; Neoplasm Proteins; Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured

2015
Syntheses of methylated catechins and theaflavins using 2-nitrobenzenesulfonyl group to protect and deactivate phenol.
    The Journal of antibiotics, 2016, Volume: 69, Issue:4

    Topics: Antioxidants; Benzenesulfonates; Biflavonoids; Catechin; Methylation; Oxidation-Reduction; Polyphenols; Structure-Activity Relationship

2016
Separation of catechins and O-methylated (-)-epigallocatechin gallate using polyamide thin-layer chromatography.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016, Apr-01, Volume: 1017-1018

    Topics: Catechin; Chromatography, Thin Layer; Methylation; Nylons

2016
Preparation of Methylated Products of A-type Procyanidin Trimers in Cinnamon Bark and Their Protective Effects on Pancreatic β-Cell.
    Journal of food science, 2016, Volume: 81, Issue:5

    Topics: Animals; Anthocyanins; Antioxidants; Apoptosis; Benzoquinones; Biflavonoids; Catechin; Catechols; Chromatography, High Pressure Liquid; Cinnamomum zeylanicum; Hypoglycemic Agents; Insulin-Secreting Cells; Methylation; Molecular Structure; Palmitic Acid; Plant Bark; Plant Extracts; Polyphenols; Proanthocyanidins; Protective Agents; Rats; Spectrometry, Mass, Electrospray Ionization

2016
A comprehensive evaluation of the [2-
    Free radical biology & medicine, 2016, Volume: 99

    Topics: Animals; Biotransformation; Carbon Radioisotopes; Catechin; Duodenum; Feces; Glucuronides; Hippurates; Humans; Ileum; Jejunum; Lactones; Male; Metabolome; Methylation; Rats; Rats, Sprague-Dawley; Species Specificity

2016
Profiling and identification of (-)-epicatechin metabolites in rats using ultra-high performance liquid chromatography coupled with linear trap-Orbitrap mass spectrometer.
    Drug testing and analysis, 2017, Volume: 9, Issue:8

    Topics: Animals; Antioxidants; Catechin; Chromatography, High Pressure Liquid; Data Mining; Glucuronides; Hydroxylation; Hypoglycemic Agents; Male; Metabolic Networks and Pathways; Methylation; Rats; Spectrometry, Mass, Electrospray Ionization

2017
[Effects of EGCG on Proliferation, Cell Cycle and DAPK1 Gene Methylation of Acute Promyelocytic Leukemia NB4 Cell Line].
    Zhongguo shi yan xue ye xue za zhi, 2018, Volume: 26, Issue:5

    Topics: Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Death-Associated Protein Kinases; Humans; Leukemia, Promyelocytic, Acute; Methylation

2018
Regiospecific methylation of all the hydroxyls in (+)-catechin by a stepwise differentiation strategy.
    Journal of the science of food and agriculture, 2019, Volume: 99, Issue:8

    Topics: Acylation; Catechin; Hydroxyl Radical; Isomerism; Methylation; Phenols

2019
Epigallocatechin-3-gallate (EGCG) Alters Histone Acetylation and Methylation and Impacts Chromatin Architecture Profile in Human Endothelial Cells.
    Molecules (Basel, Switzerland), 2020, May-16, Volume: 25, Issue:10

    Topics: Acetylation; Activating Transcription Factor 2; Catechin; Cell Line; Chromatin; Chromobox Protein Homolog 5; Chromosomal Proteins, Non-Histone; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Human Umbilical Vein Endothelial Cells; Humans; Methylation; Myeloid-Lymphoid Leukemia Protein; p300-CBP Transcription Factors; Protein Processing, Post-Translational; Tea

2020
Anion carboxymethylated β-glucan alleviates undesirable binding between procyanidins and β-galactosidase.
    Food chemistry, 2021, May-15, Volume: 344

    Topics: beta-Galactosidase; beta-Glucans; Biflavonoids; Catechin; Kinetics; Lotus; Methylation; Proanthocyanidins; Protein Binding

2021
Synthesis and evaluation of stereoisomers of methylated catechin and epigallocatechin derivatives on modulating P-glycoprotein-mediated multidrug resistance in cancers.
    European journal of medicinal chemistry, 2021, Dec-15, Volume: 226

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Catechin; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Methylation; Molecular Structure; Stereoisomerism; Structure-Activity Relationship

2021
Methylated (-)-epigallocatechin 3-O-gallate potentiates the effect of split vaccine accompanied with upregulation of Toll-like receptor 5.
    Scientific reports, 2021, 11-29, Volume: 11, Issue:1

    Topics: Animals; Catechin; Drug Administration Schedule; Drug Synergism; Female; Hemagglutination; Immunity, Humoral; Influenza Vaccines; Japan; Macrophages; Methylation; Mice; Mice, Inbred BALB C; Plant Extracts; Spleen; Tea; Toll-Like Receptor 5; Up-Regulation

2021
EGCG Promotes FUS Condensate Formation in a Methylation-Dependent Manner.
    Cells, 2022, 02-09, Volume: 11, Issue:4

    Topics: Arginine; Catechin; Glycine; Humans; Methylation; Neurodegenerative Diseases; Proteins; RNA-Binding Protein FUS

2022