catechin has been researched along with isomethyleugenol in 94 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (5.32) | 18.7374 |
1990's | 11 (11.70) | 18.2507 |
2000's | 41 (43.62) | 29.6817 |
2010's | 32 (34.04) | 24.3611 |
2020's | 5 (5.32) | 2.80 |
Authors | Studies |
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Briere, N; Castonguay, A; Pepin, P | 1 |
McGrath, RM; Smith, A | 1 |
Hackett, AM | 1 |
Griffiths, LA; Hackett, AM; Wermeille, M | 1 |
Hundt, HK; van der Merwe, PJ | 1 |
Griffiths, LA; Hackett, AM; Shaw, IC | 1 |
Griffiths, LA; Turin, E; Wermeille, M | 1 |
Chen, WF; Ho, CT; Hong, JY; Shi, ST; Smith, TJ; Wang, ZY; Yang, CS | 1 |
Inagake, M; Iwashima, A; Kikuoka, N; Kitao, Y; Matsumoto, H; Nakatani, H; Nishimura, H; Oya, K; Takahashi, T; Yamane, T | 1 |
Hugouvieux-Cotte-Pattat, N; Nasser, W; Robert-Baudouy, J; Tardy, F | 1 |
Da Silva, EL; Piskula, M; Terao, J | 1 |
Piskula, MK; Terao, J | 1 |
Hara, Y; Matsumoto, N; Nanjo, F; Okushio, K; Suzuki, M | 2 |
Donovan, JL; Luthria, DL; Stremple, P; Waterhouse, AL | 1 |
Crespy, V; Demigné, C; Manach, C; Morand, C; Régérat, F; Rémésy, C; Texier, O | 1 |
Hattori, M; Kakuda, H; Ma, C; Nakamura, N; Qiao, J; Yu, H | 1 |
Maeda-Yamamoto, M; Miyase, T; Sano, M; Sunada, Y; Tachibana, H; Yamada, K | 1 |
Cai, MX; Conney, AH; Patel, UK; Zhu, BT | 1 |
Debnam, ES; Hahn, U; Kuhnle, G; Rice-Evans, C; Schroeter, H; Shenoy, B; Spencer, JP; Srai, SK | 1 |
Coddeville, B; Cren-Olivé, C; Déprez, S; Lebrun, S; Rolando, C | 1 |
Baba, S; Nakamura, T; Natsume, M; Osakabe, N; Takizawa, T; Terao, J; Yasuda, A | 1 |
Hahn, U; Kuhnle, G; Rice-Evans, C; Schroeter, H; Spencer, JP; Srai, SK; Tyrrell, RM | 1 |
Dhar, K; Hosny, M; Rosazza, JP | 1 |
Crossthwaithe, AJ; Kuhnle, G; Rice-Evans, C; Schroeter, H; Spencer, JP; Williams, RJ | 1 |
Baba, S; Muto, Y; Natsume, M; Osakabe, N; Takizawa, T; Terao, J | 1 |
Cai, MX; Conney, AH; Lee, AJ; Patel, UK; Zhu, BT | 1 |
Cuendet, M; Fong, HH; Hawthorne, ME; Kardono, LB; Kinghorn, AD; Mehta, RG; Pezzuto, JM; Riswan, S; Su, BN | 1 |
Fujioka, T; Kouno, I; Mihashi, K; Mine, C; Tanaka, T; Watarumi, S; Zhang, YJ | 1 |
Degawa, M; Maeda-Yamamoto, M; Miyase, T; Sano, M; Suzuki, M; Yoshida, R | 1 |
Lu, H; Meng, X; Yang, CS | 1 |
Spencer, JP | 1 |
Chikumoto, T; Inagaki, N; Kawahara, H; Kawakami, T; Kawakami, Y; Kitaura, J; Maeda-Yamamoto, M; Miyase, T; Nagai, H; Sano, M; Tachibana, H | 1 |
Conney, AH; Nagai, M; Zhu, BT | 1 |
Furuno, K; Kadowaki, M; Ootani, E; Sugihara, N | 1 |
Chiu, FL; Lin, JK | 1 |
Agusta, A; Maehara, S; Ohashi, K; Shibuya, H; Simanjuntak, P | 1 |
Galati, G; Lin, A; O'Brien, PJ; Sultan, AM | 1 |
Ardèvol, A; Arola, L; Bladé, C; Fernandez-Larrea, J; García-Ramírez, B; Salvadó, MJ | 1 |
Chan, TH; Chen, D; Daniel, KG; Dou, QP; Landis-Piwowar, KR; Wan, SB | 1 |
Jiang, Y; Kakuda, Y; Shi, J; Shixian, Q; VanCrey, B | 1 |
Chan, TH; Dou, QP; Kuhn, DJ; Landis-Piwowar, KR; Wan, SB; Wiegand, RA | 1 |
Schewe, T; Sies, H; Steffen, Y | 1 |
Andrews, LG; Berletch, JB; Katiyar, SK; Liu, C; Love, WK; Tollefsbol, TO | 1 |
Ando, Y; Chuang, YC; Miyoshi, H; Takahashi, T; Tanaka, H | 1 |
Fujimura, Y; Miyase, T; Tachibana, H; Umeda, D; Yamada, K; Yano, S | 1 |
Ishiyama, K; Kawano, S; Miyase, T; Nishimura, M; Sano, M; Watanabe, A | 1 |
Bai, HW; Shim, JY; Yu, J; Zhu, BT | 1 |
Bai, HW; Nagai, M; Shim, JY; Zhu, BT | 1 |
Rodríguez-López, JN; Sánchez-del-Campo, L | 1 |
Chan, TH; Chen, D; Dou, QP; Huo, C; Landis-Piwowar, KR; Wan, SB | 1 |
Dueñas, M; González-Manzano, S; González-Paramás, A; Santos-Buelga, C | 2 |
Appeldoorn, MM; Gruppen, H; Hollman, PC; Vincken, JP | 1 |
Aihara, Y; Akizawa, T; Furuta, T; Kan, T; Konishi, M; Wakimoto, T; Yoshida, A | 1 |
Cheng, HY; Lee, SC; Liu, SY; Wu, SS; Yan, RH | 1 |
Dou, QP; Landis-Piwowar, KR | 1 |
Dou, QP | 1 |
Bishop, SC; Fukui, M; Kang, KS; Wen, Y; Yamabe, N; Zhu, BT | 1 |
Hirotsu, K; Miyoshi, H; Tachibana, H; Takahashi, T; Tanaka, H; Yamanouchi, M | 1 |
Cao, H; Chen, T; Liu, C; Xiao, J; Xu, X; Yang, F | 1 |
Baran, J; Bukowska-Straková, K; Papiez, MA; Wiczkowski, W | 1 |
Brown, AL; Dadd, T; Dick, JL; Jackson, KG; Mayes, AE; Miller, RJ; Minihane, AM; Nicol, B | 1 |
Agarwal, C; Agarwal, R; Gu, M; Shrestha, SP; Thompson, JA; Wempe, MF | 1 |
Esatbeyoglu, T; Homann, T; Kulling, SE; Rawel, HM; Weinert, CH; Wiese, S; Winterhalter, P | 1 |
de Roos, B; Duthie, GG; Hollands, W; Kroon, PA; Needs, PW; Ostertag, LM; Saha, S | 1 |
Keen, CL; Kwik-Uribe, C; Ottaviani, JI; Schroeter, H | 1 |
Kwik-Uribe, C; Oruna-Concha, MJ; Rodriguez-Mateos, A; Spencer, JP; Vidal, A | 1 |
Heber, D; Henning, SM; Wang, P | 2 |
Anglès, N; Macià, A; Morelló, JR; Motilva, MJ; Ortega, N; Romero, MP; Rubió, L; Serra, A | 1 |
Fukui, M; Kang, KS; Wen, Y; Yamabe, N; Zhu, BT | 1 |
Imberty, A; Le Bourvellec, C; Renard, CM; Watrelot, AA | 1 |
Chen, X; Kai, G; Ni, X; Xiao, J | 1 |
Chen, X; Kai, G; Xiao, J; Yamamoto, K | 1 |
Abe, Y; Kanda, T; Kirita, M; Maeda-Yamamoto, M; Miyata, S; Tagashira, M; Tanaka, Y | 2 |
Buer, J; Geffers, R; Kehrmann, J; Probst-Kepper, M; Steinmann, J; Tatura, R; Zeschnigk, M | 1 |
Kanda, T; Kirita, M; Maeda-Yamamoto, M; Tagashira, M; Tanaka, Y | 1 |
Cifuentes-Gomez, T; Gonzalez-Salvador, I; Heiss, C; Kelm, M; Ottaviani, JI; Rodriguez-Mateos, A; Schroeter, H; Spencer, JP | 1 |
Chow, LM; Duan, LX; Hu, X; Jiang, T; Li, XM; Liu, T; Liu, Z; Wan, SB; Wang, BC; Wong, IL; Yuan, J; Zhang, XY | 1 |
Aihara, Y; Asakawa, T; Furuta, T; Hamashima, Y; Hirose, Y; Inai, M; Kan, T; Kawabe, Y; Manabe, T; Sakurada, A; Wakimoto, T; Yoshida, A | 1 |
Chen, Q; Huang, J; Lin, H; Lin, Y; Liu, Z; Wang, K; Yu, S | 1 |
Chen, K; Chen, L; Jia, Q; Li, Y; Wang, H; Wang, T; Yuan, P | 1 |
Borges, G; Crozier, A; van der Hooft, JJJ | 1 |
Dai, S; Lu, J; Shang, Z; Wang, F; Wu, X; Zhang, J | 1 |
Jankun, J; Matthews-Brzozowska, T; Matthews-Kozanecka, M; Skrzypczak-Jankun, E; Wyganowska-Świątkowska, M | 1 |
Gao, HY; He, XW; Shi, X; Yan, W; Yang, W | 1 |
Cai, H; Hong, S; Liu, S; Wang, S | 1 |
Balcerczyk, A; Biesiekierska, M; Ciesielski, O | 1 |
Sun, Z; Wang, J; Xie, B | 1 |
Chow, LMC; Li, FX; Li, P; Liu, Z; Sun, W; Wan, SB; Wang, BC; Wang, XK; Wong, ILK | 1 |
Fujimura, Y; Hamagami, H; Horie, F; Kumazoe, M; Tachibana, H; Takamatsu, K; Tanaka, H; Yoshitomi, R | 1 |
Bourgeois, B; Habacher, H; Khanna, Y; Lenard, AJ; Madl, T; Madreiter-Sokolowski, C; Zhou, Q | 1 |
8 review(s) available for catechin and isomethyleugenol
Article | Year |
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The metabolism of flavonoid compounds in mammals.
Topics: Animals; Bile; Catechin; Enterohepatic Circulation; Flavonoids; Glucuronates; Glycosides; Humans; Hydrolysis; Liver; Methylation; Oxidation-Reduction; Sulfates; Tissue Distribution | 1986 |
Metabolism of tea flavonoids in the gastrointestinal tract.
Topics: Biological Availability; Catechin; Colon; Digestive System; Flavonoids; Gastric Mucosa; Humans; Ileum; Intestinal Absorption; Jejunum; Methylation; Saliva; Tea | 2003 |
Green tea extract thermogenesis-induced weight loss by epigallocatechin gallate inhibition of catechol-O-methyltransferase.
Topics: Adipose Tissue, Brown; Animals; Camellia sinensis; Catechin; Catechol O-Methyltransferase Inhibitors; Enzyme Inhibitors; Male; Methylation; Norepinephrine; Plant Extracts; Rats; Thermogenesis; Weight Loss | 2006 |
Green tea polyphenols as a natural tumour cell proteasome inhibitor.
Topics: Anticarcinogenic Agents; Catechin; Methylation; Proteasome Inhibitors; Tea; Ubiquitin | 2008 |
Polyphenols: biological activities, molecular targets, and the effect of methylation.
Topics: Anticarcinogenic Agents; Catechin; Flavonoids; Humans; Methylation; Phenols; Polyphenols; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Ubiquitin | 2008 |
A review on structure-activity relationship of dietary polyphenols inhibiting α-amylase.
Topics: alpha-Amylases; Anthocyanins; Catechin; Coumaric Acids; Galactosides; Glucosides; Glycosylation; Humans; Hydrolyzable Tannins; Hydroxylation; Methylation; Molecular Structure; Polyphenols; Proanthocyanidins; Structure-Activity Relationship | 2013 |
Advance in dietary polyphenols as α-glucosidases inhibitors: a review on structure-activity relationship aspect.
Topics: alpha-Glucosidases; Anthocyanins; Catechin; Chalcone; Coumaric Acids; Diet; Glycoside Hydrolase Inhibitors; Glycosylation; Humans; Hydrogenation; Hydroxylation; Methylation; Polyphenols; Proanthocyanidins; Stilbenes; Structure-Activity Relationship; Tannins | 2013 |
Can EGCG Alleviate Symptoms of Down Syndrome by Altering Proteolytic Activity?
Topics: Animals; Biomarkers; Catechin; Down Syndrome; Humans; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Methylation; Proteolysis; Signal Transduction; Tissue Plasminogen Activator | 2018 |
6 trial(s) available for catechin and isomethyleugenol
Article | Year |
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Bioavailability of (-)-epicatechin upon intake of chocolate and cocoa in human volunteers.
Topics: Adult; Biological Availability; Cacao; Catechin; Chromatography, High Pressure Liquid; Chromatography, Liquid; Humans; Intestinal Absorption; Male; Mass Spectrometry; Methylation | 2000 |
A preliminary investigation of the impact of catechol-O-methyltransferase genotype on the absorption and metabolism of green tea catechins.
Topics: Amino Acid Substitution; Catechin; Catechol O-Methyltransferase; Dietary Supplements; Female; Genetic Association Studies; Homozygote; Humans; Intestinal Absorption; Kinetics; Male; Methylation; Middle Aged; Phenols; Pilot Projects; Plant Extracts; Polymorphism, Single Nucleotide; Tea | 2012 |
Human O-sulfated metabolites of (-)-epicatechin and methyl-(-)-epicatechin are poor substrates for commercial aryl-sulfatases: implications for studies concerned with quantifying epicatechin bioavailability.
Topics: Administration, Oral; Arylsulfatases; Biological Availability; Biotransformation; Catechin; Chromatography, Liquid; Cross-Over Studies; England; Female; Glucuronidase; Humans; Hydrogen-Ion Concentration; Hydrolysis; Male; Methylation; Reproducibility of Results; Substrate Specificity; Sulfuric Acid Esters; Tandem Mass Spectrometry; Time Factors | 2012 |
Intake of dietary procyanidins does not contribute to the pool of circulating flavanols in humans.
Topics: Adolescent; Adult; Analytic Sample Preparation Methods; Biflavonoids; Catechin; Cross-Over Studies; Diet; Double-Blind Method; Flavonoids; Glucuronides; Humans; Lactones; Male; Methylation; Molecular Weight; Polymerization; Postprandial Period; Proanthocyanidins; Young Adult | 2012 |
Influence of sugar type on the bioavailability of cocoa flavanols.
Topics: Adult; Biological Availability; Cacao; Catechin; Cross-Over Studies; Double-Blind Method; Female; Flavonoids; Humans; Male; Maltose; Methylation; Sucrose; Sugar Alcohols; Sweetening Agents | 2012 |
Influence of age on the absorption, metabolism, and excretion of cocoa flavanols in healthy subjects.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Beverages; Cacao; Catechin; Cross-Over Studies; Flavonoids; Glucuronides; Half-Life; Humans; Intestinal Absorption; Kinetics; Lactones; Male; Methylation; Patient Dropouts; Renal Elimination; Stereoisomerism; Sulfuric Acid Esters; Young Adult | 2015 |
80 other study(ies) available for catechin and isomethyleugenol
Article | Year |
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Modulation of 4-(methylnitrosamino)-1-(3-pyridyl)-1 butanone demethylation and denitrosation by rat liver microsomes.
Topics: Animals; Carcinogens; Catechin; Dimethylnitrosamine; Enzyme Induction; Formaldehyde; Kinetics; Male; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Nitrates; Nitrogen Dioxide; Nitrosamines; Nitrosation; Rats; Rats, Inbred F344 | 1991 |
The isolation of large molecular mass procyanidins from grain sorghum and their interaction with [14C]methyl bovine serum albumins.
Topics: Animals; Biflavonoids; Binding, Competitive; Carbon Radioisotopes; Catechin; Cattle; Chromatography, Gel; Edible Grain; Methylation; Molecular Weight; Osmolar Concentration; Proanthocyanidins; Serum Albumin, Bovine | 1990 |
The quantitative disposition of 3-O-methyl-(+)-[U-14C]catechin in man following oral administration.
Topics: Administration, Oral; Adult; Benzopyrans; Catechin; Glucuronates; Glucuronic Acid; Humans; Male; Metabolic Clearance Rate; Methylation; Species Specificity; Sulfates | 1985 |
Metabolism of (+)-catechin and some of its C-6 and C-8 substituted derivatives in the isolated perfused pig liver.
Topics: Animals; Benzopyrans; Bile; Catechin; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Hydrolysis; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylation; Perfusion; Structure-Activity Relationship; Swine | 1984 |
3'-O-methyl-(+)-catechin glucuronide and 3'-O-methyl-(+)-catechin sulphate: new urinary metabolites of (+)-catechin in the rat and the marmoset.
Topics: Animals; Benzopyrans; Callitrichinae; Catechin; Glucuronates; Kinetics; Male; Methylation; Rats; Rats, Inbred Strains; Species Specificity; Sulfates | 1982 |
Identification of the major urinary metabolites of (+)-catechin and 3-O-methyl-(+)-catechin in man.
Topics: Benzopyrans; Biotransformation; Catechin; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Magnetic Resonance Spectroscopy; Methylation | 1983 |
Effects of green tea and black tea on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation, DNA methylation, and lung tumorigenesis in A/J mice.
Topics: Animals; Beverages; Carcinogens; Catechin; DNA; Female; Flavonoids; Lung; Lung Neoplasms; Methylation; Mice; Microsomes; Nitrosamines; Pyridines; Tea | 1994 |
Inhibition of 1,2-dimethylhydrazine-induced oxidative DNA damage by green tea extract in rat.
Topics: 1,2-Dimethylhydrazine; 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Animals; Anticarcinogenic Agents; Azoxymethane; Biotransformation; Catechin; Colon; Deoxyguanosine; Diazonium Compounds; Dimethylhydrazines; DNA; DNA Damage; Free Radical Scavengers; Injections, Subcutaneous; Intestinal Mucosa; Kidney; Liver; Male; Methylation; Methylazoxymethanol Acetate; Oxidation-Reduction; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Tea | 1995 |
Comparative analysis of the five major Erwinia chrysanthemi pectate lyases: enzyme characteristics and potential inhibitors.
Topics: Calcium Chloride; Catechin; Cations, Divalent; Dickeya chrysanthemi; Enzyme Inhibitors; Escherichia coli; Hot Temperature; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Methylation; Pectins; Polysaccharide-Lyases; Recombinant Fusion Proteins; Salicylates; Salicylic Acid; Substrate Specificity | 1997 |
Enhancement of antioxidative ability of rat plasma by oral administration of (-)-epicatechin.
Topics: Administration, Oral; Amidines; Animals; Antioxidants; Catechin; Cholesterol Esters; Copper Sulfate; Free Radicals; In Vitro Techniques; Lipid Peroxidation; Male; Methylation; Oxidants; Plasma; Rats; Rats, Wistar; Vitamin E | 1998 |
Accumulation of (-)-epicatechin metabolites in rat plasma after oral administration and distribution of conjugation enzymes in rat tissues.
Topics: Animals; Arylsulfotransferase; Catechin; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Glucuronates; Glucuronosyltransferase; Hydrolysis; Intestinal Absorption; Intestinal Mucosa; Kidney; Liver; Male; Methylation; Rats; Rats, Wistar; Sulfates | 1998 |
Identification of (-)-epicatechin metabolites and their metabolic fate in the rat.
Topics: Administration, Oral; Animals; Bile; Catechin; Chromatography, High Pressure Liquid; Glucuronates; Magnetic Resonance Spectroscopy; Male; Methylation; Rats; Rats, Wistar; Spectrometry, Mass, Fast Atom Bombardment | 1999 |
Methylation of tea catechins by rat liver homogenates.
Topics: Animals; Catechin; Chromatography, High Pressure Liquid; Flavonoids; Liver; Magnetic Resonance Spectroscopy; Male; Methylation; Rats; Rats, Wistar; S-Adenosylmethionine; Spectrometry, Mass, Fast Atom Bombardment; Tea | 1999 |
Analysis of (+)-catechin, (-)-epicatechin and their 3'- and 4'-O-methylated analogs. A comparison of sensitive methods.
Topics: Catechin; Chromatography, High Pressure Liquid; Electrochemistry; Humans; Magnetic Resonance Spectroscopy; Methylation; Reference Standards; Sensitivity and Specificity; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1999 |
Comparison of the bioavailability of quercetin and catechin in rats.
Topics: Animals; Biological Availability; Catechin; Chromatography, High Pressure Liquid; Diet; Glucuronides; Liver; Male; Methylation; Quercetin; Rats; Rats, Wistar; Sulfates | 1999 |
Inhibitory effects on HIV-1 protease of constituents from the wood of Xanthoceras sorbifolia.
Topics: Anthocyanins; Catechin; Crystallography, X-Ray; HIV Protease; HIV Protease Inhibitors; Humans; Magnetic Resonance Spectroscopy; Methylation; Plants, Medicinal; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared; Triterpenes; Wood | 2000 |
Identification of a methylated tea catechin as an inhibitor of degranulation in human basophilic KU812 cells.
Topics: Basophils; Catechin; Cell Degranulation; Cell Line; Humans; Methylation | 2000 |
O-Methylation of tea polyphenols catalyzed by human placental cytosolic catechol-O-methyltransferase.
Topics: Catechin; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Cytosol; Dose-Response Relationship, Drug; Female; Flavonoids; Humans; Hydrogen-Ion Concentration; Kinetics; Mass Spectrometry; Methylation; Phenols; Placenta; Polymers; Pregnancy; S-Adenosylhomocysteine; Tea | 2000 |
Epicatechin and catechin are O-methylated and glucuronidated in the small intestine.
Topics: Animals; Biological Transport; Catechin; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Glucuronides; Ileum; Intestine, Small; Jejunum; Mass Spectrometry; Methylation; Rats | 2000 |
Characterization of methylation site of monomethylflavan-3-ols by liquid chromatography/electrospray ionization tandem mass spectrometry.
Topics: Catechin; Chromatography, Liquid; Methylation; Spectrometry, Mass, Electrospray Ionization | 2000 |
Epicatechin and its in vivo metabolite, 3'-O-methyl epicatechin, protect human fibroblasts from oxidative-stress-induced cell death involving caspase-3 activation.
Topics: Antioxidants; Apoptosis; Caspase 3; Caspases; Catechin; Cells, Cultured; Fibroblasts; Humans; Hydrogen Peroxide; Lipoproteins, LDL; Methylation; Mitochondria; Oxidative Stress | 2001 |
Hydroxylations and methylations of quercetin, fisetin, and catechin by Streptomyces griseus.
Topics: Catechin; Flavonoids; Flavonols; Hydroxylation; Methylation; Quercetin; Spectrum Analysis; Streptomyces | 2001 |
Contrasting influences of glucuronidation and O-methylation of epicatechin on hydrogen peroxide-induced cell death in neurons and fibroblasts.
Topics: Animals; Caspase 3; Caspases; Catechin; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Dermis; Fibroblasts; Flavonoids; Glucuronides; Humans; Hydrogen Peroxide; Methylation; Mice; Neurons | 2001 |
In vivo comparison of the bioavailability of (+)-catechin, (-)-epicatechin and their mixture in orally administered rats.
Topics: Administration, Oral; Animals; Area Under Curve; Biological Availability; Catechin; Chromatography, High Pressure Liquid; Chromatography, Liquid; Intestinal Absorption; Male; Methylation; Rats; Rats, Sprague-Dawley; Stereoisomerism | 2001 |
Rapid conversion of tea catechins to monomethylated products by rat liver cytosolic catechol-O-methyltransferase.
Topics: Animals; Catechin; Catechol O-Methyltransferase; Cytosol; Female; Flavonoids; Hydrogen-Ion Concentration; Kinetics; Liver; Mass Spectrometry; Methylation; Phenols; Polymers; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; Tea | 2001 |
Constituents of the bark and twigs of Artocarpus dadah with cyclooxygenase inhibitory activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylation; Animals; Benzofurans; Breast; Catechin; Cell Transformation, Neoplastic; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Indonesia; Isoenzymes; Membrane Proteins; Methylation; Mice; Mice, Inbred BALB C; Molecular Structure; Moraceae; Nuclear Magnetic Resonance, Biomolecular; Organ Culture Techniques; Plant Bark; Plant Extracts; Plant Shoots; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Stilbenes | 2002 |
Accumulation of epigallocatechin quinone dimers during tea fermentation and formation of theasinensins.
Topics: Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Fermentation; Hydrolysis; Japan; Methylation; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Phenazines; Plant Leaves; Plants, Medicinal; Quinones; Tea | 2002 |
Epimerization of tea catechins and O-methylated derivatives of (-)-epigallocatechin-3-O-gallate: relationship between epimerization and chemical structure.
Topics: Catechin; Hot Temperature; Hydrogen-Ion Concentration; Methylation; Molecular Structure; Plant Extracts; Plant Leaves; Solutions; Stereoisomerism; Tea; Water | 2003 |
Enzymology of methylation of tea catechins and inhibition of catechol-O-methyltransferase by (-)-epigallocatechin gallate.
Topics: Animals; Catechin; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cytosol; Enzyme Inhibitors; Female; Gas Chromatography-Mass Spectrometry; Glucuronides; Intestinal Mucosa; Intestines; Liver; Male; Methylation; Mice; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Species Specificity; Swine; Tea | 2003 |
O-methylated catechins from tea leaves inhibit multiple protein kinases in mast cells.
Topics: Animals; Anti-Allergic Agents; Catechin; Enzyme Activation; Enzyme Inhibitors; Mast Cells; Methylation; Mice; Mice, Inbred CBA; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Passive Cutaneous Anaphylaxis; Plant Leaves; Protein Kinase C; Protein Kinase C beta; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Signal Transduction; Tea | 2004 |
Strong inhibitory effects of common tea catechins and bioflavonoids on the O-methylation of catechol estrogens catalyzed by human liver cytosolic catechol-O-methyltransferase.
Topics: Catalysis; Catechin; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrogens, Catechol; Flavonoids; Humans; Liver; Methylation; Plant Extracts; Tea | 2004 |
Inhibitory effects of catechin gallates on o-methyltranslation of protocatechuic acid in rat liver cytosolic preparations and cultured hepatocytes.
Topics: Animals; Catechin; Catechol O-Methyltransferase; Cells, Cultured; Chromatography, High Pressure Liquid; Cytosol; Hepatocytes; Hydroxybenzoates; Liver; Male; Methylation; Rats; Rats, Wistar | 2005 |
HPLC analysis of naturally occurring methylated catechins, 3' '- and 4' '-methyl-epigallocatechin gallate, in various fresh tea leaves and commercial teas and their potent inhibitory effects on inducible nitric oxide synthase in macrophages.
Topics: Camellia sinensis; Catechin; Fermentation; Methylation; Plant Leaves; Seasons; Taiwan | 2005 |
Stereoselective oxidation at C-4 of flavans by the endophytic fungus Diaporthe sp. isolated from a tea plant.
Topics: Ascomycota; Camellia; Catechin; Chromatography, High Pressure Liquid; DNA, Fungal; Flavins; Methylation; Oxidation-Reduction; Oxygen; Reverse Transcriptase Polymerase Chain Reaction; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Stereoisomerism | 2005 |
Cellular and in vivo hepatotoxicity caused by green tea phenolic acids and catechins.
Topics: Alanine Transaminase; Animals; Antioxidants; Catechin; Gallic Acid; Glutathione; Hydroxybenzoates; Iron; Liver; Male; Mass Spectrometry; Methylation; Mice; NAD(P)H Dehydrogenase (Quinone); Rats; Rats, Sprague-Dawley; Tea | 2006 |
Tetramethylated dimeric procyanidins are detected in rat plasma and liver early after oral administration of synthetic oligomeric procyanidins.
Topics: Absorption; Animals; Biflavonoids; Catechin; Chromatography, High Pressure Liquid; Dimerization; Hydrogen-Ion Concentration; Liver; Male; Mass Spectrometry; Methylation; Proanthocyanidins; Rats; Rats, Wistar; Structure-Activity Relationship | 2006 |
Methylation of green tea polyphenols affects their binding to and inhibitory poses of the proteasome beta5 subunit.
Topics: Catechin; Chymotrypsin; Dose-Response Relationship, Drug; Flavonoids; Methylation; Models, Molecular; Molecular Conformation; Phenols; Polyphenols; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Protein Subunits; Tea | 2006 |
Methylation suppresses the proteasome-inhibitory function of green tea polyphenols.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Death; Flavonoids; Humans; Jurkat Cells; Methylation; Phenols; Polyphenols; Protease Inhibitors; Proteasome Inhibitors; Tea | 2007 |
(-)-Epicatechin elevates nitric oxide in endothelial cells via inhibition of NADPH oxidase.
Topics: Acetophenones; Angiotensin II; Catechin; Cells, Cultured; Cyclic GMP; Endothelial Cells; Enzyme Inhibitors; Humans; Methylation; Molecular Structure; NADPH Oxidases; Nitric Oxide; Signal Transduction; Umbilical Cord | 2007 |
Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG.
Topics: Adenocarcinoma; Apoptosis; Breast Neoplasms; Catechin; Cell Division; Cell Line, Tumor; DNA Methylation; E2F1 Transcription Factor; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histones; HL-60 Cells; Humans; Lysine; Male; Methylation; Neoplasm Proteins; Promoter Regions, Genetic; Protein Processing, Post-Translational; RNA, Messenger; RNA, Neoplasm; Telomerase | 2008 |
Solid-phase synthesis of epigallocatechin gallate derivatives.
Topics: Anticarcinogenic Agents; Antioxidants; Catechin; Methylation | 2007 |
Relationship between the biological activities of methylated derivatives of (-)-epigallocatechin-3-O-gallate (EGCG) and their cell surface binding activities.
Topics: Basophils; Catechin; Cell Line; Cell Membrane; Humans; Methylation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Structure-Activity Relationship | 2007 |
Determination of theaflavins including methylated theaflavins in black tea leaves by solid-phase extraction and HPLC analysis.
Topics: Biflavonoids; Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Ethanol; Fermentation; Methylation; Plant Leaves | 2007 |
Biochemical and molecular modeling studies of the O-methylation of various endogenous and exogenous catechol substrates catalyzed by recombinant human soluble and membrane-bound catechol-O-methyltransferases.
Topics: Catechin; Catechol O-Methyltransferase; Catecholamines; Catechols; Computer Simulation; Estrogens, Catechol; Flavonoids; Humans; Membrane Proteins; Methylation; Models, Biological; Models, Molecular; Protein Binding; Recombinant Proteins | 2007 |
Molecular modelling study of the mechanism of high-potency inhibition of human catechol-O-methyltransferase by (-)-epigallocatechin-3-O-gallate.
Topics: Animals; Catechin; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Kinetics; Methylation; Models, Molecular; Rats; Swine | 2008 |
Targeting the methionine cycle for melanoma therapy with 3-O-(3,4,5-trimethoxybenzoyl)-(-)-epicatechin.
Topics: Adenosine; Animals; Antineoplastic Agents; Apoptosis; Base Sequence; Blotting, Western; Caspase 3; Catechin; Cell Line, Tumor; DNA Primers; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Melanoma; Methionine; Methylation; Mice; Microscopy, Confocal; Microscopy, Electron; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
Preparation and characterization of catechin sulfates, glucuronides, and methylethers with metabolic interest.
Topics: Catechin; Chromatography, High Pressure Liquid; Ethers; Glucuronides; Methylation; Spectrometry, Mass, Electrospray Ionization; Sulfuric Acid Esters | 2009 |
Antioxidant evaluation of O-methylated metabolites of catechin, epicatechin and quercetin.
Topics: Antioxidants; Catechin; Ferric Compounds; Fluorescence Recovery After Photobleaching; Free Radical Scavengers; Hydrogen-Ion Concentration; Methylation; Molecular Structure; Oxidation-Reduction; Quercetin; Reference Standards | 2010 |
Procyanidin dimers A1, A2, and B2 are absorbed without conjugation or methylation from the small intestine of rats.
Topics: Animals; Biflavonoids; Catechin; Dimerization; Intestinal Absorption; Intestine, Small; Metabolic Detoxication, Phase II; Methylation; Perfusion; Polymers; Proanthocyanidins; Rats | 2009 |
Regioselective synthesis of methylated epigallocatechin gallate via nitrobenzenesulfonyl (Ns) protecting group.
Topics: Animals; Catechin; Chemistry, Organic; Chemistry, Pharmaceutical; Drug Design; Humans; Inhibitory Concentration 50; Matrix Metalloproteinase 1; Matrix Metalloproteinase 7; Methylation; Mice; Models, Chemical; Recombinant Proteins; Stereoisomerism; Tea | 2009 |
Screen and genetic assessment of tea germplasms with elevated methylated catechin, (-)-epigallocatechin-3-O-(3-O-methyl)gallate.
Topics: Breeding; Caffeine; Camellia sinensis; Catechin; Methylation; Phylogeny; Plant Leaves; Species Specificity; Taiwan | 2009 |
Molecular mechanisms of green tea polyphenols.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis; Biological Availability; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Female; Flavonoids; Humans; Male; Methylation; Mice; Phenols; Polyphenols; Prodrugs; Proteasome Inhibitors; Rats; Tea; Ubiquitinated Proteins | 2009 |
Dual beneficial effects of (-)-epigallocatechin-3-gallate on levodopa methylation and hippocampal neurodegeneration: in vitro and in vivo studies.
Topics: Animals; Biological Products; Catechin; Catechol O-Methyltransferase Inhibitors; Cell Death; Cell Line; Enzyme Inhibitors; Hippocampus; Humans; Kainic Acid; Levodopa; Male; Methylation; Mice; Neurons; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2010 |
Solid-phase synthesis of a combinatorial methylated (±)-epigallocatechin gallate library and the growth-inhibitory effects of these compounds on melanoma B16 cells.
Topics: Animals; Antineoplastic Agents; Catechin; Cell Line, Tumor; Combinatorial Chemistry Techniques; Hydrogenation; Melanoma, Experimental; Methylation; Mice; Small Molecule Libraries | 2010 |
Molecular property-binding affinity relationship of flavonoids for common rat plasma proteins in vitro.
Topics: Animals; Apigenin; Blood Proteins; Catechin; Cattle; Chromatography, Reverse-Phase; Flavonoids; Glycosylation; Humans; Hydroxylation; Isomerism; Methylation; Protein Binding; Rats; Structure-Activity Relationship; Surface Properties | 2011 |
Antileukemic action of (-)-epicatechin in the spleen of rats with acute myeloid leukemia.
Topics: Animals; Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; Body Weight; Catechin; Cell Line; Comet Assay; DNA Damage; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Leukemia, Myeloid, Acute; Methylation; Organ Size; Oxidation-Reduction; Phosphatidylserines; Purines; Rats; Spleen | 2010 |
Glucuronidation and methylation of procyanidin dimers b2 and 3,3″-di-o-galloyl-b2 and corresponding monomers epicatechin and 3-o-galloyl-epicatechin in mouse liver.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biflavonoids; Catechin; Dimerization; Glucuronides; Grape Seed Extract; Male; Methylation; Mice; Mice, Inbred C57BL; Microsomes, Liver; Proanthocyanidins | 2012 |
Methylation of catechins and procyanidins by rat and human catechol-O-methyltransferase: metabolite profiling and molecular modeling studies.
Topics: Animals; Catechin; Catechol O-Methyltransferase; Computer Simulation; Cytosol; Female; Humans; Liver; Methylation; Models, Molecular; Molecular Structure; Placenta; Pregnancy; Pregnancy Proteins; Proanthocyanidins; Rats; Rats, Wistar; S-Adenosylmethionine; Species Specificity; Substrate Specificity | 2012 |
Quercetin increased bioavailability and decreased methylation of green tea polyphenols in vitro and in vivo.
Topics: Animals; Biological Availability; Catechin; Catechol O-Methyltransferase; Cell Line, Tumor; Down-Regulation; Humans; Male; Methylation; Mice; Mice, SCID; Neoplasms; Polyphenols; Quercetin; Tea; Up-Regulation | 2012 |
Quercetin increased the antiproliferative activity of green tea polyphenol (-)-epigallocatechin gallate in prostate cancer cells.
Topics: Androgens; Anticarcinogenic Agents; Catechin; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Humans; Male; Methylation; Prostatic Neoplasms; Quercetin; Tea | 2012 |
Distribution of procyanidins and their metabolites in rat plasma and tissues in relation to ingestion of procyanidin-enriched or procyanidin-rich cocoa creams.
Topics: Animals; Antioxidants; Cacao; Catechin; Corylus; Diet; Food, Fortified; Glucuronides; Kidney; Kinetics; Liver; Male; Methylation; Nuts; Plant Extracts; Proanthocyanidins; Rats; Rats, Wistar; Seeds; Spain; Surface Properties; Tissue Distribution | 2013 |
Beneficial effects of natural phenolics on levodopa methylation and oxidative neurodegeneration.
Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Antiparkinson Agents; Carbidopa; Catechin; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Disease Models, Animal; Excitatory Amino Acid Agonists; Fluoresceins; Glial Fibrillary Acidic Protein; Hippocampus; Hydroxybenzoates; In Vitro Techniques; Kainic Acid; Levodopa; Male; Methylation; Mice; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Reserpine; Time Factors; Tyrosine | 2013 |
Interactions between pectic compounds and procyanidins are influenced by methylation degree and chain length.
Topics: Catechin; Citrus; Flavonoids; Food Handling; Fruit; Hexuronic Acids; Malus; Methylation; Pectins; Polymerization; Proanthocyanidins | 2013 |
O-methylated theaflavins suppress the intracellular accumulation of triglycerides from terminally differentiated human visceral adipocytes.
Topics: Adipocytes; Biflavonoids; Catechin; Cell Differentiation; Down-Regulation; Humans; Intra-Abdominal Fat; Methylation; Triglycerides | 2013 |
Impact of 5-aza-2'-deoxycytidine and epigallocatechin-3-gallate for induction of human regulatory T cells.
Topics: Azacitidine; Catechin; Decitabine; Forkhead Transcription Factors; Humans; Male; Methylation; Oligonucleotide Array Sequence Analysis; T-Lymphocytes, Regulatory | 2014 |
Metabolic stability and inhibitory effect of O-methylated theaflavins on H2O2-induced oxidative damage in human HepG2 cells.
Topics: Biflavonoids; Catechin; Drug Stability; Hep G2 Cells; Humans; Hydrogen Peroxide; Methylation; Oxidative Stress; Oxygen | 2014 |
Cloning and characterization of a novel O-methyltransferase from Flammulina velutipes that catalyzes methylation of pyrocatechol and pyrogallol structures in polyphenols.
Topics: Amino Acid Sequence; Catechin; Catechol O-Methyltransferase; Catechols; Cloning, Molecular; Escherichia coli; Flammulina; Fungal Proteins; Gallic Acid; Methylation; Methyltransferases; Molecular Sequence Data; Molecular Structure; Polyphenols; Pyrogallol; Recombinant Proteins; Substrate Specificity | 2015 |
Potent and Nontoxic Chemosensitizer of P-Glycoprotein-Mediated Multidrug Resistance in Cancer: Synthesis and Evaluation of Methylated Epigallocatechin, Gallocatechin, and Dihydromyricetin Derivatives.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Catechin; Cell Proliferation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavonols; Humans; Methylation; Models, Molecular; Molecular Structure; Neoplasm Proteins; Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured | 2015 |
Syntheses of methylated catechins and theaflavins using 2-nitrobenzenesulfonyl group to protect and deactivate phenol.
Topics: Antioxidants; Benzenesulfonates; Biflavonoids; Catechin; Methylation; Oxidation-Reduction; Polyphenols; Structure-Activity Relationship | 2016 |
Separation of catechins and O-methylated (-)-epigallocatechin gallate using polyamide thin-layer chromatography.
Topics: Catechin; Chromatography, Thin Layer; Methylation; Nylons | 2016 |
Preparation of Methylated Products of A-type Procyanidin Trimers in Cinnamon Bark and Their Protective Effects on Pancreatic β-Cell.
Topics: Animals; Anthocyanins; Antioxidants; Apoptosis; Benzoquinones; Biflavonoids; Catechin; Catechols; Chromatography, High Pressure Liquid; Cinnamomum zeylanicum; Hypoglycemic Agents; Insulin-Secreting Cells; Methylation; Molecular Structure; Palmitic Acid; Plant Bark; Plant Extracts; Polyphenols; Proanthocyanidins; Protective Agents; Rats; Spectrometry, Mass, Electrospray Ionization | 2016 |
A comprehensive evaluation of the [2-
Topics: Animals; Biotransformation; Carbon Radioisotopes; Catechin; Duodenum; Feces; Glucuronides; Hippurates; Humans; Ileum; Jejunum; Lactones; Male; Metabolome; Methylation; Rats; Rats, Sprague-Dawley; Species Specificity | 2016 |
Profiling and identification of (-)-epicatechin metabolites in rats using ultra-high performance liquid chromatography coupled with linear trap-Orbitrap mass spectrometer.
Topics: Animals; Antioxidants; Catechin; Chromatography, High Pressure Liquid; Data Mining; Glucuronides; Hydroxylation; Hypoglycemic Agents; Male; Metabolic Networks and Pathways; Methylation; Rats; Spectrometry, Mass, Electrospray Ionization | 2017 |
[Effects of EGCG on Proliferation, Cell Cycle and DAPK1 Gene Methylation of Acute Promyelocytic Leukemia NB4 Cell Line].
Topics: Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Death-Associated Protein Kinases; Humans; Leukemia, Promyelocytic, Acute; Methylation | 2018 |
Regiospecific methylation of all the hydroxyls in (+)-catechin by a stepwise differentiation strategy.
Topics: Acylation; Catechin; Hydroxyl Radical; Isomerism; Methylation; Phenols | 2019 |
Epigallocatechin-3-gallate (EGCG) Alters Histone Acetylation and Methylation and Impacts Chromatin Architecture Profile in Human Endothelial Cells.
Topics: Acetylation; Activating Transcription Factor 2; Catechin; Cell Line; Chromatin; Chromobox Protein Homolog 5; Chromosomal Proteins, Non-Histone; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Human Umbilical Vein Endothelial Cells; Humans; Methylation; Myeloid-Lymphoid Leukemia Protein; p300-CBP Transcription Factors; Protein Processing, Post-Translational; Tea | 2020 |
Anion carboxymethylated β-glucan alleviates undesirable binding between procyanidins and β-galactosidase.
Topics: beta-Galactosidase; beta-Glucans; Biflavonoids; Catechin; Kinetics; Lotus; Methylation; Proanthocyanidins; Protein Binding | 2021 |
Synthesis and evaluation of stereoisomers of methylated catechin and epigallocatechin derivatives on modulating P-glycoprotein-mediated multidrug resistance in cancers.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Catechin; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Methylation; Molecular Structure; Stereoisomerism; Structure-Activity Relationship | 2021 |
Methylated (-)-epigallocatechin 3-O-gallate potentiates the effect of split vaccine accompanied with upregulation of Toll-like receptor 5.
Topics: Animals; Catechin; Drug Administration Schedule; Drug Synergism; Female; Hemagglutination; Immunity, Humoral; Influenza Vaccines; Japan; Macrophages; Methylation; Mice; Mice, Inbred BALB C; Plant Extracts; Spleen; Tea; Toll-Like Receptor 5; Up-Regulation | 2021 |
EGCG Promotes FUS Condensate Formation in a Methylation-Dependent Manner.
Topics: Arginine; Catechin; Glycine; Humans; Methylation; Neurodegenerative Diseases; Proteins; RNA-Binding Protein FUS | 2022 |