catechin has been researched along with epigallocatechin gallate in 5056 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (0.08) | 18.7374 |
| 1990's | 150 (2.97) | 18.2507 |
| 2000's | 1446 (28.60) | 29.6817 |
| 2010's | 2675 (52.91) | 24.3611 |
| 2020's | 781 (15.45) | 2.80 |
| Authors | Studies |
|---|---|
| Acoca, S; Beauparlant, P; Bélec, L; Billot, X; Cluse, L; Goulet, D; Johnstone, RW; Marcellus, RC; Murthy Madiraju, SR; Nguyen, M; Purisima, E; Roulston, A; Serfass, L; Shore, GC; Viallet, J; Watson, M; Wiegmans, A | 1 |
| Amić, D; Lucić, B | 1 |
| Kalra, S; Khatik, GL; Kumar, GN; Kumar, R; Narang, R; Nayak, SK; Singh, SK; Sudhakar, K | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Kim, HJ; Lee, JS; Lee, YS; Park, H | 1 |
| Backlund, A; Bohlin, L; Gottfries, J; Larsson, J | 1 |
| Backleh-Sohrt, M; Ekici, P; Leupold, G; Parlar, H | 1 |
| Brun, R; Lack, G; Perozzo, R; Rüedi, P; Scapozza, L; Tasdemir, D | 1 |
| Gestwicki, JE; Reinke, AA; Seh, HY | 1 |
| Carver, JA; Duggan, PJ; Ecroyd, H; Liu, Y; Meyer, AG; Tranberg, CE | 1 |
| Cho, SJ; Park, KD | 1 |
| Cai, S; Chu, L; Gao, F; Ji, B; Jia, G; Liu, J; Liu, Y; Wang, A; Wei, Y; Wu, W; Xie, L; Zhang, D; Zhou, F | 1 |
| Kim, JK; Lee, BG; Manir, MM; Moon, SS | 1 |
| Akoto, M; Avery, VM; Duffy, S; Hagen, TJ; Helgren, TR; Igbinoba, O; Lee, P; Sciotti, RJ | 1 |
| Bicknell, KA; Farrimond, JA; Putnam, SE; Swioklo, S; Watson, KA; Williamson, EM | 1 |
| Cahlikova, L; Chlebek, J; Havrankova, J; Hofman, J; Hostalkova, A; Lundova, T; Musilek, K; Novotna, E; Wsol, V; Zemanova, L | 1 |
| Adachi, I; Ito, T; Kato, A; Onikata, S; Tomohara, K | 1 |
| Jin, YS | 1 |
| Albiñana, CB; Brynda, J; Fanfrlík, J; Flieger, M; Hodek, J; Karlukova, E; Konvalinka, J; Kožíšek, M; Machara, A; Majer, P; Radilová, K; Weber, J; Zima, V | 1 |
| Fong, J; Korobkova, EA; Maran, U; Oja, M; Rice, M; Samuels, K; Sapse, AM; Williams, AK; Wong, B | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Tao, P | 1 |
| Lu, WH; Xiao, PG; Zhang, PP; Zhu, M | 1 |
| Kabuto, H; Mori, A; Yokoi, I | 1 |
| Hara, Y; Horiuchi, Y; Okubo, S; Shimamura, T; Toda, M | 1 |
| Chosa, H; Hara, Y; Okubo, S; Shimamura, T; Toda, M | 1 |
| Agarwal, R; Bhatia, AK; Katiyar, SK; Mukhtar, H; Wang, ZY | 1 |
| Fujiki, H; Horiuchi, T; Nishiwaki, S; Nishiwaki-Matsushima, R; Okabe, S; Okuda, T; Suganuma, M; Sugimura, T; Yatsunami, J; Yoshizawa, S | 1 |
| Hara, Y; Hu, ZQ; Okubo, S; Shimamura, T; Toda, M | 1 |
| Frenkel, K; Ye, JJ; Zadunaisky, JA | 1 |
| Asano, K; Hara, Y; Sakagami, H; Shimamura, T | 1 |
| Arimoto, S; Hayatsu, H; Inada, N; Kakutani, T; Mori, K; Negishi, T; Okuda, T; Sakata, I | 1 |
| Amin, SG; Chung, FL; Han, C; Ho, CT; Xu, Y | 1 |
| Ikeda, I; Imasato, Y; Nagao, H; Nakayama, M; Sasaki, E; Sugano, M; Takeo, T; Yayabe, F | 1 |
| Hara, Y; Koike, H; Mukoyama, A; Nishimura, S; Shimamura, T; Toda, M; Ushijima, H | 1 |
| Ozaki, M; Shikita, M; Suzuki, K; Uchida, S | 1 |
| Akachi, S; Hagiwara, N; Inagake, M; Kim, M; Kitao, Y; Kuwata, K; Okuzumi, J; Takahashi, T; Tateishi, M; Yamane, T | 1 |
| Ikeuchi, M; Maruyama, I; Okuda, T; Sakata, I | 1 |
| Fujiki, H; Fujita, Y; Kuwata, K; Okuda, T; Okuzumi, J; Takahashi, T; Tanaka, M; Yamane, T | 1 |
| Cheng, SJ | 1 |
| Chisaka, T; Fujimura, H; Kubomura, Y; Matsuda, H; Mochizuki, M; Yamahara, J | 1 |
| Isemura, M; Mukae, N; Narumi, K; Nukiwa, T; Ogata, K; Satoh, K; Suzuki, Y | 1 |
| Fukutomi, Y; Moriwaki, H; Muto, Y; Ninomiya, M; Nishida, H; Nishiwaki, S; Omori, M; Suganuma, M | 1 |
| Takeo, T; Unno, T | 1 |
| Chan, MM; Ho, CT; Huang, HI | 1 |
| Hiipakka, RA; Liao, S | 1 |
| Guo, J; Hiipakka, RA; Kokontis, JM; Liao, S; Umekita, Y | 1 |
| Bhimani, RS; Frenkel, K; Grunberger, D; Troll, W | 1 |
| Hara, Y; Miura, S; Osawa, T; Sano, M; Tomita, I; Tomita, T; Watanabe, J | 1 |
| Hara, Y; Matsumoto, N; Nanjo, F; Okushio, K; Suzuki, M | 2 |
| Fujiki, H; Inagake, M; Kitao, Y; Kuwata, K; Oya, K; Suganuma, M; Takahashi, T; Yamane, T | 1 |
| Hou, JW; Shen, SR; Xin, WJ; Yang, XQ; Zhao, BL | 1 |
| Arakawa, K; Hara, Y; Kono, K; Takeda, S; Tatara, I | 1 |
| Hara, Y; Sato, A; Shirai, T | 1 |
| Nagao, M; Oguri, A; Wakabayashi, K; Weisburger, JH | 1 |
| Fujiki, H; Komori, A; Ohta, T; Okabe, S; Sueoka, E; Suganuma, M; Yatsunami, J | 1 |
| Hara, Y; Okubo, S; Shimamura, T; Toda, M; Toyoshima, Y | 1 |
| Hara, Y; Nakayama, M; Okubo, S; Shimamura, T; Suzuki, K; Toda, M | 1 |
| Frenkel, K; Furuya, H; Nishiwaki, S; Nishiwaki-Matsushima, R; Okabe, S; Suganuma, M; Troll, W; Verma, AK; Yatsunami, J; Yoshizawa, S | 1 |
| Arimoto, S; Hayatsu, H; Negishi, T | 1 |
| Dohi, K; Hattori, M; Iwano, M; Oura, H; Yokozawa, T | 1 |
| Isemura, M; Motomiya, M; Narumi, K; Satoh, K; Suzuki, Y | 1 |
| Abe, S; Fujiki, H; Hara, K; Kim, SJ; Komori, A; Okabe, S; Suganuma, M; Yatsunami, J | 1 |
| Cottle, S; Lea, MA; Sadhukhan, AK; Wang, ZY; Xiao, Q; Yang, CS | 1 |
| Frenkel, K; Wei, H | 1 |
| Chung, FL; Eklind, KI; Morse, MA; Xu, Y | 1 |
| Araki, R; Inoue, S; Osborne, MP; Telang, NT | 1 |
| Lee, SF; Liang, YC; Lin, JK | 1 |
| Chen, J; Han, C; Hu, G | 1 |
| Iwata, Y; Kikuoka, N; Kitao, Y; Matsumoto, H; Nakatani, H; Oya, K; Takahashi, T; Yamane, T | 1 |
| Aizawa, M; Kim, M; Sakanaka, S; Yamamoto, T | 1 |
| Fujiki, H; Iida, N; Kim, SJ; Komori, A; Okabe, S; Sueoka, E; Suganuma, M | 1 |
| Akai, G; Hasegawa, K; Yoshinaga, K; Yoshioka, H | 1 |
| Ariza, ME; Oberyszyn, AS; Robertson, FM; Williams, MV | 1 |
| Bhattacharya, M; Fiala, ES; Li, H; Sodum, RS | 1 |
| Matsuo, N; Mori, M; Shoji, K; Sugano, M; Yamada, K; Yamashita, K | 1 |
| Hiramoto, K; Kikugawa, K; Ojima, N; Sako, K | 1 |
| Alberts, DS; Dorr, R; Dvorakova, K; Gensler, HL; Timmermann, BN; Valcic, S; Wächter, GA | 1 |
| Yoshizawa, S | 1 |
| Kuroda, Y | 1 |
| Isemura, M; Itoi, T; Koide, T; Odani, S; Sazuka, M; Suzuki, Y | 1 |
| Kakuda, T; Kanegae, T; Nagoya, T; Sakane, I; Takihara, T; Tsukamoto, S | 1 |
| Itakura, H; Kondo, K; Takeo, T; Unno, T | 1 |
| Asano, Y; Eto, T; Niho, Y; Ogo, T; Okamura, S; Otsuka, T | 1 |
| Endo, S; Komatsu, K; Matsuura, S; Shoji, S; Tauchi, H; Yano, N | 1 |
| Hirose, M; Mizoguchi, Y; Shirai, T; Tanaka, H; Yamaguchi, T; Yaono, M | 1 |
| Agarwal, R; Katiyar, SK; Mohan, RR; Mukhtar, H | 1 |
| Stammler, G; Volm, M | 1 |
| Fujiki, H; Komori, A; Kozu, T; Okabe, S; Sakai, Y; Sueoka, E; Sueoka, N; Suganuma, M | 1 |
| Fujiki, H; Imanishi, Y; Kimura, S; Kitano, K; Nam, KY | 1 |
| Jankun, J; Selman, SH; Skrzypczak-Jankun, E; Swiercz, R | 1 |
| Miyazawa, T; Nakagawa, K | 2 |
| Akiyama, J; Chida, K; Hara, Y; Hayakawa, H; Iwata, M; Reshad, K; Sato, A; Shirai, T; Taniguchi, M | 1 |
| Chen, ZY; Fung, KP; Ho, KY; Luk, YS; Zhang, A; Zhu, QY | 1 |
| Achiwa, Y; Hibasami, H; Imai, K; Katsuzaki, H; Komiya, T | 1 |
| Nakazato, K; Shiozaki, T; Sugiyama, K; Takeo, T | 1 |
| Dashwood, R; Hasaniya, N; Hernaez, J; Xu, M; Youn, K | 1 |
| Lin, JK; Lin, YL | 1 |
| Yang, CS | 2 |
| Fujiki, H; Hayashi, M; Komori, A; Okabe, S; Sueoka, E; Suganuma, M | 1 |
| Chen, L; Lee, MJ; Li, H; Yang, CS | 1 |
| Chen, CF; Liang, YC; Lin, JK; Lin-shiau, SY | 2 |
| Dong, Z; Huang, C; Ma, W; Yang, CS | 1 |
| Hara, Y; Imazawa, H; Isemura, M; Mita, T; Sazuka, M; Shoji, Y | 1 |
| Kurosaki, H; Saito, K; Yoshinaga, K; Yoshioka, H | 1 |
| Chan, MM; Fong, D; Ho, CT; Huang, HI | 1 |
| Agarwal, R; Ahmad, N; Feyes, DK; Mukhtar, H; Nieminen, AL | 1 |
| Aliaga, C; Balentine, DA; Boone, CW; Kelloff, GJ; Pittman, B; Reinhardt, J; Rivenson, A; Steele, VE; Weisburger, JH; Zang, E | 1 |
| Miyazawa, T; Nakagawa, K; Okuda, S | 1 |
| Chou, TC; Edelstein, D; Khafif, A; Sacks, PG; Schantz, SP | 1 |
| Hara, Y; Hu, ZQ; Okubo, S; Shimamura, T; Zenda, N | 1 |
| Higashi, Y; Imai, K; Nakachi, K; Suemasu, K; Suga, K; Takeo, T | 1 |
| Kim, K; Liao, J; Yang, CS; Yang, GY; Yurkow, EJ | 1 |
| Hasuma, T; Kennedy, DO; Matsui-Yuasa, I; Nishimura, S; Otani, S; Yano, Y | 1 |
| Isemura, M; Isemura, S; Sazuka, M | 1 |
| Fujiki, H; Imai, K; Komori, A; Kozu, T; Nakachi, K; Okabe, S; Sueoka, E; Sueoka, N; Suga, K; Suganuma, M; Tada, Y | 1 |
| Bombardelli, E; Brusamolino, A; Gardana, C; Morazzoni, P; Pietta, PG; Simonetti, P | 1 |
| al-Rawi, M; Edelstein, D; Khafif, A; Sacks, PG; Schantz, SP | 1 |
| Naasani, I; Seimiya, H; Tsuruo, T | 1 |
| Chen, KY; Chen, ZP; Ho, CT; Schell, JB | 1 |
| Baba, N; Kaneko, T; Matsuo, M | 1 |
| Butler, R; Paschka, AG; Young, CY | 1 |
| Fujiki, H; Ito, H; Okabe, S; Oniyama, M; Suganuma, M; Tada, Y | 1 |
| Bombardelli, E; Brusamolino, A; Gardana, C; Morazzoni, P; Pietta, P; Simonetti, P | 1 |
| de Villiers, WJ; McClain, CJ; Varilek, GW; Yang, F | 1 |
| Kouno, I; Kusano, R; Tanaka, T | 1 |
| Bair, WB; Barthelman, M; Bowden, GT; Chen, W; Dong, Z; Stickland, KK; Timmermann, BN; Valcic, S | 1 |
| Fujiki, H; Kai, Y; Okabe, S; Sueoka, E; Sueoka, N; Suganuma, M | 1 |
| Chen, L; Lee, MJ; Yang, CS | 1 |
| Asano, Y; Eto, T; Niho, Y; Ogo, T; Otsuka, T; Suganuma, M | 1 |
| Elmets, CA; Katiyar, SK; Matsui, MS; Mukhtar, H | 1 |
| Alberts, DS; Dorr, RT; Dvorakova, K; Timmermann, B; Valcic, S | 1 |
| Bowden, GT; Chen, W; Dong, Z; Timmermann, BN; Valcic, S | 1 |
| Fujita, K; Gondo, Y; Kamataki, T; Katsuki, M; Muto, S; Shioyama, Y; Yokoi, T | 1 |
| Ahn, HY; Hadizadeh, KR; Sachinidis, A; Seul, C; Vetter, H; Yun, YP | 1 |
| Cao, R; Cao, Y | 1 |
| Fujiki, H; Imai, K; Kimura, S; Nakachi, K; Okabe, S; Sueoka, E; Suga, K; Suganuma, M | 1 |
| Conney, AH; Huang, M; Lou, Y; Lu, Y; Xie, J | 1 |
| Jacobsen, NE; Liebler, DC; Muders, A; Timmermann, BN; Valcic, S | 1 |
| Chen, YC; Ho, CT; Liang, YC; Lin, JK; Lin, YL; Lin-Shiau, SY | 1 |
| Ahmad, N; Gupta, S; Mukhtar, H | 2 |
| Tsuchiya, H | 2 |
| Frass, M; Gmeiner, B; Handler, S; Hofbauer, R; Kapiotis, S; Speiser, W | 1 |
| Ge, N; Zhang, HY; Zhang, ZY | 1 |
| Aida, M; Fujiki, H; Kim, SJ; Nomura, T; Ochiai, Y; Okabe, S; Park, K; Suganuma, M | 1 |
| Chu, IS; Hour, TC; Liang, YC; Lin, JK | 1 |
| Kondo, K; Kurihara, M; Miyata, N; Suzuki, T; Toyoda, M | 1 |
| Surh, Y | 1 |
| Fujiki, H; Imai, K; Matsuyama, S; Nakachi, K; Okabe, S; Sueoka, E; Sueoka, N; Suganuma, M | 2 |
| L'Allemain, G | 1 |
| Fujiki, H | 2 |
| Challa, A; Cooper, KD; Katiyar, SK; McCormick, TS; Mukhtar, H | 1 |
| Albini, A; Benelli, R; Biggin, S; Cavallarin, N; Garbisa, S; Sartor, L | 1 |
| Chen, ZY; Huang, Y; Tsang, D; Zhu, QY | 1 |
| Fukuda, K; Haishi, D; Hiroto, M; Inada, Y; Kodera, Y; Matsushima, A; Nishimura, H; Noguchi, Y | 1 |
| Brown, MD | 1 |
| Amano, F; Aoi, N; Hara-Kudo, Y; Iwaki, M; Kumagai, S; Okubo, T; Sugita-Konishi, Y | 1 |
| Lewis, N; Rafferty, KA; Rafferty, NS; Zigman, S | 1 |
| Chung, KH; Kang, WS; Lim, IH; Park, JB; Yoo, HS; Yuk, DY; Yun, YP | 1 |
| Corvese, D; Weitberg, AB | 1 |
| Fukuma, M; Goto, N; Hashimoto, E; Hiji, Y; Iwashita, J; Kobayashi, N; Nagata, K; Ogura, K; Sugimoto, I; Yasokawa, M; Yasuda, H | 1 |
| Goto, K; Hara, Y; Mori, M; Nanjo, F | 1 |
| Ando, T; Hayakawa, F; Hoshino, N; Kimura, T | 1 |
| Clark, AM; ElSohly, HN; Li, XC; Nimrod, AC | 1 |
| Bors, W; Michel, C | 1 |
| Hara, Y; Hashimoto, T; Kumazawa, S; Nakayama, T; Nanjo, F | 1 |
| Bors, W; Michel, C; Stettmaier, K | 1 |
| Hiipakka, RA; Kao, YH; Liao, S | 2 |
| Sadzuka, Y; Sonobe, T; Sugiyama, T | 1 |
| Béliveau, R; Brossard, M; Demeule, M; Gingras, D; Pagé, M | 1 |
| Bradlow, HL; Osborne, MP; Sepkovic, DW; Telang, NT | 1 |
| Ahmad, N; Gupta, S; Mukhtar, H; Nieminen, AL | 1 |
| Byrnes, JJ; Fujiyoshi, T; Ghosh, SK; Karasuyama, M; Lema, C; Li, HC; Lou, H; Sonoda, J; Sonoda, S; Yashiki, S | 1 |
| Fujiki, H; Imai, K; Nakachi, K; Okabe, S; Sueoka, E; Suga, K; Suganuma, M | 1 |
| Goldberg, VM; Haqqi, TM; Islam, N; Islam, S; Johnstone, B; Kermode, T; Malemud, CJ; Moskowitz, RW; Mukhtar, H | 1 |
| Butler, R; Mitchell, SH; Ren, F; Young, CY; Zhang, S | 1 |
| Ho, CT; Huang, TC; LaVoie, EJ; Yang, CS; Yu, Y; Zhu, N | 1 |
| Harada, M; Kataoka, M; Kiura, K; Matsuo, K; Mimoto, J; Takata, I; Ueoka, H; Yoshino, T | 1 |
| Hara, Y; Isemura, M; Kawahara, H; Maeda-Yamamoto, M; Tahara, N; Tsuji, K | 1 |
| Cobrinik, D; Liberto, M | 1 |
| Johnson, MK; Loo, G | 1 |
| Kim, S; Lee, S; Suh, S | 1 |
| Clement, MV; Halliwell, B; Long, LH | 1 |
| Liu, Z; Liu, ZL; Ma, LP; Yang, L; Zhou, B | 1 |
| Fujimaki, N; Hayashi, H; Kitts, DD; Nagasawa, T; Nishizawa, N | 1 |
| Webb, T | 1 |
| Chen, PC; Ho, CT; Lin, JK; Lin-Shiau, SY | 1 |
| Chen, Y; Li, RC; Zhu, M | 1 |
| Aiello, FB; Brunetti, M; Caltagirone, S; Natali, PG; Piantelli, M; Poggi, A; Ranelletti, FO; Rossi, C | 1 |
| Hayakawa, S; Matsui, T; Shimizu, K; Suzuki, Y; Suzuki-Karasaki, M; Yamaki, M; Yamashita, K; Yoshimaru, T | 1 |
| Chiang, HC; Chou, FP; Chu, YC; Hsu, JD; Wang, CJ | 1 |
| Arai, K; Kusu, F; Yang, B | 1 |
| Hishinuma, T; Ishizawa, F; Mizugaki, M; Yamazaki, T | 1 |
| Han, Y; Hu, D; Li, S; Tan, X; Zhang, Y; Zhou, D | 1 |
| Alberts, DS; Bangert, JL; Dorr, RT; Stratton, SP | 1 |
| Bowden, GT; Dong, Z; Huang, C; Ma, WY; Miyamoto, K; Nomura, M; Yang, CS | 1 |
| Ahmad, N; Cheng, P; Mukhtar, H | 1 |
| Bridge, A; Morré, DJ; Morré, DM; Wu, LY | 1 |
| Chen, NY; Dong, Z; Ma, WY; Yang, CS | 1 |
| Tanaka, R | 1 |
| Burr, JA; Liebler, DC; Timmermann, BN; Valcic, S | 1 |
| Hara, Y; Kida, K; Matsumoto, N; Nanjo, F; Suzuki, M | 1 |
| Miura, Y; Yagasaki, K; Zhang, G | 1 |
| Fraga, CG; Lotito, SB | 1 |
| Agarwal, R | 1 |
| Bode, AM; Chen, N; Dong, Z; Ma, W; Nomura, M | 1 |
| Abe, I; Kashiwagi, K; Noguchi, H | 1 |
| Aldini, G; Bombardelli, E; Carini, M; Maffei Facino, R; Morazzoni, P | 1 |
| Chung, J; Ho, CT; Li, C; Liao, J; Yang, CS; Yang, GY; Yurkow, EJ | 1 |
| Brackney, W; Denison, MS; Guenette, DK; Pickwell, GV; Quattrochi, LC; Shih, H; Williams, SN | 1 |
| Abe, I; Isemura, M; Noguchi, H; Saeki, K; Seki, T; Yuo, A | 1 |
| Arai, S; Hara, Y; Kobayashi, Y; Miyamoto, Y; Satsu, H; Shimizu, M; Suzuki, K; Suzuki, M | 1 |
| Maeda-Yamamoto, M; Miyase, T; Sano, M; Suzuki, M; Yoshino, K | 1 |
| Bushman, F; Hwang, Y; Rhodes, D | 1 |
| Cutter, H; Kim, C; Morré, DJ; Morré, DM; Wu, LY | 1 |
| Agarwal, R; Bhatia, N | 1 |
| Chen, Z; Huang, Y; Tsang, D; Zhu, QY | 1 |
| Hong, WK; Hsu, TC; Spitz, MR; Wang, RY; Wu, YF; Zhao, YJ | 1 |
| Abe, I; Degawa, M; Morita, R; Nemoto, K; Noguchi, H; Umehara, K | 1 |
| Afaq, F; Katiyar, SK; Mukhtar, H; Perez, A | 1 |
| Alberts, DS; Cai, Y; Chow, HH; Crowell, JA; Dorr, R; Hakim, I; Hara, Y; Shahi, F; Yang, CS | 1 |
| Fujiki, H; Ohkura, Y; Okabe, S; Suganuma, M | 1 |
| Menon, SR; Mitscher, LA; Pillai, CA; Pillai, SP; Shankel, DM; Telikepalli, H | 1 |
| Dong, Z | 1 |
| Miyazawa, T | 1 |
| Fujiki, H; Okabe, S; Sueoka, E; Sueoka, N; Suganuma, M | 1 |
| Hayakawa, S; Isemura, M; Kimura, T; Minami, T; Saeki, K; Sazuka, M | 1 |
| Albini, A; Benelli, R; Biggin, S; Garbisa, S; Salvato, B; Sartor, L | 1 |
| Crouvezier, S; Keir, D; Powell, B; Yaqoob, P | 1 |
| Chan, TH; Li, L | 1 |
| Ahn, BW; Bucana, CD; Chay, KO; Ellis, LM; Gallick, GE; Jung, YD; Kim, MS; Liu, W; Shin, BA | 1 |
| Amin, S; Chung, FL; Conaway, CC; Desai, D; Hara, Y; Hojo, H; Kohri, T; Matsumoto, N; Nanjo, F; Seto, R; Suzuki, M; Yamakawa, M | 1 |
| Zaveri, NT | 1 |
| Dou, QP; Nam, S; Smith, DM | 1 |
| Aoyagi, Y; Hayakawa, S; Isemura, M; Kimura, T; Koyama, Y; Nakamura, Y; Noro, T; Saeki, K | 1 |
| Hirano, H; Kuratsu, J; Sarker, KP; Wakimaru, N; Yokoyama, S | 1 |
| Geigerman, CM; Kelly, MR; Loo, G | 1 |
| Hu, C; Kitts, DD | 1 |
| Cavalieri, E; De Prati, AC; Dussin, D; Mariotto, S; Menegazzi, M; Suzuki, H; Tedeschi, E | 1 |
| Friedman, H; Klein, TW; Matsunaga, K; Yamamoto, Y | 3 |
| Hara, Y; Hu, ZQ; Okubo, S; Shimamura, T; Zhao, WH | 1 |
| Katiyar, SK; Mukhtar, H | 1 |
| Park, KK; Reuben, JS; Soliman, KF | 1 |
| Bertoldi, M; Gonsalvi, M; Voltattorni, CB | 1 |
| Bhaduri, A; Sarkar, A | 1 |
| Balentine, DA; Beecher, GR; Clevidence, BA; Smith, LS; Warden, BA | 1 |
| Amantana, A; Dashwood, RH; Orner, GA; Provost, C; Santana-Rios, G; Wu, SY | 1 |
| Fujita, K; Kamataki, T; Muto, S; Yamazaki, Y | 1 |
| Hayakawa, S; Isemura, M; Kaji, K; Ohta, T; Saeki, K; Sazuka, M; Shoji, Y; Suzuki, Y; Yuo, A | 1 |
| Hafer, LJ; Kavanagh, KT; Kim, DW; Mann, KK; Rogers, AE; Sherr, DH; Sonenshein, GE | 1 |
| Chen, ZY; Ho, WK; Huang, Y; Lau, CW; Law, WI; Yao, XQ | 1 |
| Bennick, A; Chakrabartty, A; Muhandiram, R; Wróblewski, K | 1 |
| Hara, Y; Hirai, K; Homma, T; Katayama, Y | 2 |
| Barve, S; de Villiers, WJ; McClain, CJ; Oz, HS; Varilek, GW; Yang, F | 1 |
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| Bakun, P; Cerbin-Koczorowska, M; Goslinski, T; Jelińska, A; Koczorowski, T; Kolasiński, E; Kuźmińska, J; Mlynarczyk, DT; Piwowarczyk, L; Stawny, M | 1 |
| Abreu, BD; Corona, SAM; Curylofo Zotti, FA; Scatolin, RS | 1 |
| Dai, Z; Jing, H; Li, D; Nie, M; Wang, X; Xu, Y; Zhang, G; Zhang, Z | 1 |
| Duan, C; Wang, R | 1 |
| Chen, P; Chen, S; Cheng, Y; Chu, Q; Fan, F; Feng, X; Gong, S; Hu, H; Lv, H; Pan, Y; Zhou, S | 1 |
| Huang, X; Julian McClements, D; Liu, W; Ma, C; Xie, Y; Zhang, L; Zou, L | 1 |
| Aguilera, P; Arluison, V; Berríos-Pastén, C; Gálvez-Silva, M; Lagos, R; Marcoleta, AE; Turbant, F; Veloso, M; Wien, F | 1 |
| Al Bawareed, O; Al Farraj, J; Al-Ameer, HJ; Al-Awaida, W; Goh, KW; Gushchina, YS; Hamad, I; Severin, AE; Srour, B; Torshin, VI | 1 |
| Cui, H; Engelhardt, UH; Wang, Y; Yin, J; Yu, J; Zhang, J; Zhao, Y | 1 |
406 review(s) available for catechin and epigallocatechin gallate
| Article | Year |
|---|---|
Recent advancements in mechanistic studies and structure activity relationship of F
Topics: Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium; Proton-Translocating ATPases; Structure-Activity Relationship | 2019 |
Recent advances in natural antifungal flavonoids and their derivatives.
Topics: Antifungal Agents; Biological Products; Flavonoids; Fungi; Humans; Mycoses | 2019 |
Anticarcinogenic effects of (-)-epigallocatechin gallate.
Topics: Animals; Anticarcinogenic Agents; Catechin; Hydrolyzable Tannins; Male; Mice; Mice, Inbred C57BL; Skin; Skin Neoplasms; Tannins; Tea; Tetradecanoylphorbol Acetate | 1992 |
A new tumor promotion pathway and its inhibitors.
Topics: Anticarcinogenic Agents; Catechin; Cyclohexanols; Diterpenes; Ethers, Cyclic; Humans; Neoplasms; Okadaic Acid; Tumor Necrosis Factor-alpha | 1994 |
Mechanisms of action of new antitumor promoters.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Carcinogens; Catechin; Diterpenes; Humans; Mice; Sesquiterpenes; Skin Neoplasms | 1993 |
Dietary inhibitors against mutagenesis and carcinogenesis.
Topics: Anticarcinogenic Agents; Antimutagenic Agents; Carcinogenicity Tests; Catechin; Chlorophyll; Diet; Hemin; Humans; Mutagenicity Tests; Neoplasms; Risk Factors | 1993 |
Inhibition of tobacco-specific nitrosamine-induced lung tumorigenesis by compounds derived from cruciferous vegetables and green tea.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Catechin; DNA; DNA Damage; Indoles; Isothiocyanates; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Rats; Rats, Inbred F344; Tea; Thiocyanates; Vegetables | 1993 |
Japanese green tea as a cancer preventive in humans.
Topics: Anticarcinogenic Agents; Catechin; Health Promotion; Humans; Japan; Neoplasms; Tea | 1996 |
Polyphenolic antioxidant (-)-epigallocatechin-3-gallate from green tea reduces UVB-induced inflammatory responses and infiltration of leukocytes in human skin.
Topics: Animals; Catechin; Dermatitis; Free Radical Scavengers; Humans; Leukocytes; Mice; Skin; Tea; Ultraviolet Rays | 1999 |
Mechanistic findings of green tea as cancer preventive for humans.
Topics: Antineoplastic Agents; Catechin; Humans; Neoplasms; Plant Extracts; Receptors, Estrogen; Receptors, Progesterone; Tea; Tumor Necrosis Factor-alpha | 1999 |
Inhibitory effect of green and black tea on tumor growth.
Topics: Animals; Apoptosis; Catechin; DNA Replication; DNA, Neoplasm; Mice; Neoplasms, Experimental; Phytotherapy; Plant Extracts; Tea | 1999 |
Prostate cancer chemoprevention by green tea.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Chemoprevention; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Evidence-Based Medicine; Humans; Male; Phytotherapy; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Factors; Tea | 1999 |
Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances.
Topics: Animals; Capsaicin; Catechin; Catechols; Curcumin; Diet; Fatty Alcohols; Humans; Mice; Neoplasms; Neoplasms, Experimental; Phenols; Plants, Edible; Plants, Medicinal; Resveratrol; Stilbenes | 1999 |
Green tea (Camellia sinensis) extract and its possible role in the prevention of cancer.
Topics: Catechin; Cell Division; Flavonoids; Humans; Neoplasms; Plant Extracts; Tea | 1999 |
Phytochemicals as modulators of cancer risk.
Topics: Anticarcinogenic Agents; Catechin; Estrogens, Non-Steroidal; Female; Humans; Indoles; Isoflavones; Isothiocyanates; Male; Neoplasms; Phytoestrogens; Plant Preparations; Plants, Edible; Risk Factors; Sulfoxides; Thiocyanates | 1999 |
A new concept of tumor promotion by tumor necrosis factor-alpha, and cancer preventive agents (-)-epigallocatechin gallate and green tea--a review.
Topics: Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinogens; Catechin; Humans; Incidence; Neoplasms; Tea; Tumor Necrosis Factor-alpha | 2000 |
Cell signaling and regulators of cell cycle as molecular targets for prostate cancer prevention by dietary agents.
Topics: Anticarcinogenic Agents; Antioxidants; Catechin; Cell Cycle; Cell Cycle Proteins; Diet; ErbB Receptors; Genistein; Humans; Male; Prostatic Neoplasms; Protein-Tyrosine Kinases; Signal Transduction; Silymarin | 2000 |
Effects of food factors on signal transduction pathways.
Topics: Anticarcinogenic Agents; Apoptosis; Biflavonoids; Carcinogens; Catechin; Cell Transformation, Neoplastic; Food; Genes, Tumor Suppressor; Humans; Neoplasms; NF-kappa B; Signal Transduction; Transcription Factor AP-1; Tumor Suppressor Protein p53 | 2000 |
Absorption, metabolism and antioxidative effects of tea catechin in humans.
Topics: Antioxidants; Catechin; Humans; Intestinal Absorption; Lipoproteins, LDL; Phosphatidylcholines; Tea | 2000 |
Cancer prevention with green tea and monitoring by a new biomarker, hnRNP B1.
Topics: Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinoma, Squamous Cell; Catechin; Chemoprevention; Cohort Studies; Drug Synergism; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Heterogeneous-Nuclear Ribonucleoproteins; Humans; Intestinal Neoplasms; Japan; Lung Neoplasms; Male; Mice; Mice, Mutant Strains; Okadaic Acid; Oligonucleotide Array Sequence Analysis; Prospective Studies; Ribonucleoproteins; Sulindac; Tea; Tumor Cells, Cultured | 2001 |
Angioprevention': angiogenesis is a common and key target for cancer chemopreventive agents.
Topics: Acetylcysteine; Angiogenesis Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Catechin; Flavonoids; Humans; Models, Biological; Neoplasms; Neovascularization, Pathologic; Protease Inhibitors; Receptors, Cytoplasmic and Nuclear | 2002 |
The medicinal action of androgens and green tea epigallocatechin gallate.
Topics: Androgens; Animals; Catechin; Complementary Therapies; Female; Humans; Male; Medicine, East Asian Traditional; Phytotherapy; Plant Extracts; Prostatic Hyperplasia; Prostatic Neoplasms; Sensitivity and Specificity; Tea | 2001 |
A new function of green tea: prevention of lifestyle-related diseases.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cardiovascular Diseases; Catechin; Cohort Studies; Cricetinae; Female; Gene Expression Regulation; Humans; Interleukin-6; Japan; Life Style; Lung; Male; Mice; Mice, Transgenic; Neoplasms, Experimental; NF-kappa B; Okadaic Acid; Phytotherapy; Primary Prevention; Prospective Studies; Pulmonary Fibrosis; Rats; Risk; Tea; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2001 |
Inhibition of tumour invasion and angiogenesis by epigallocatechin gallate (EGCG), a major component of green tea.
Topics: Angiogenesis Inhibitors; Anticarcinogenic Agents; Catechin; Humans; Neoplasm Invasiveness; Neoplasms; Neovascularization, Pathologic; Phytotherapy; Plant Extracts; Tea | 2001 |
Anti-invasive effects of green tea polyphenol epigallocatechin-3-gallate (EGCG), a natural inhibitor of metallo and serine proteases.
Topics: Catechin; Flavonoids; Humans; Metalloendopeptidases; Neoplasm Invasiveness; Phenols; Polymers; Serine Proteinase Inhibitors; Tea | 2002 |
[Cancer prevention with green tea: reality and wishful thinking].
Topics: Animals; Carcinogens; Catechin; Cell Transformation, Neoplastic; Humans; Neoplasms; Tea; Treatment Outcome | 2002 |
Green tea: cancer preventive beverage and/or drug.
Topics: Antineoplastic Agents; Beverages; Catechin; Humans; Neoplasms; Tea | 2002 |
Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions.
Topics: Animals; Antioxidants; Biological Availability; Biomarkers; Cardiovascular Diseases; Catechin; Chronic Disease; Flavonoids; Free Radical Scavengers; Humans; Neoplasms; Oxidative Stress; Phenols; Polymers; Reactive Oxygen Species; Tea | 2003 |
Molecular targets for green tea in prostate cancer prevention.
Topics: Animals; Antineoplastic Agents; Apoptosis; Catechin; Chemoprevention; Clinical Trials as Topic; Humans; Male; Metalloendopeptidases; Mice; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Tea; Tumor Cells, Cultured | 2003 |
Chemoprevention of nonmelanoma skin cancer: experience with a polyphenol from green tea.
Topics: Antineoplastic Agents, Phytogenic; Catechin; Chemoprevention; Clinical Trials as Topic; Flavonoids; Humans; Phenols; Polyphenols; Skin Neoplasms; Tea; Ultraviolet Rays | 2003 |
Tea and cancer prevention: studies in animals and humans.
Topics: Animals; Apoptosis; Caffeine; Catechin; Clinical Trials as Topic; Flavonoids; Humans; Lung Neoplasms; Mice; Mouth Neoplasms; Neoplasms; Phenols; Polyphenols; Rats; Smoking; Tea | 2003 |
Catechins and the treatment of breast cancer: possible utility and mechanistic targets.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Catechin; Female; Humans; Tamoxifen; Tea | 2003 |
Is green tea good for HIV-1 infection?
Topics: Antiviral Agents; Catechin; HIV Infections; HIV-1; Humans; Phytotherapy; Plant Preparations; Tea | 2003 |
Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (-)-epigallocatechin-3-gallate: implications for neurodegenerative diseases.
Topics: Animals; Catechin; Flavonoids; Humans; Neurodegenerative Diseases; Neuroprotective Agents; Phenols; Polyphenols; Signal Transduction; Tea | 2004 |
Chemopreventive potential of epigallocatechin gallate and genistein: evidence from epidemiological and laboratory studies.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Cycle; Diet; Epidemiologic Methods; Estrogen Antagonists; Food; Genistein; Humans; Isoflavones; Neoplasms; Phytoestrogens; Plant Preparations | 2004 |
Green tea polyphenols and cancer chemoprevention: multiple mechanisms and endpoints for phase II trials.
Topics: Anticarcinogenic Agents; Biological Availability; Camellia sinensis; Catechin; Catechol O-Methyltransferase; Clinical Trials, Phase II as Topic; Flavonoids; Humans; Mutation; Phenols; Plant Leaves; Polyphenols; Structure-Activity Relationship | 2004 |
Neurological mechanisms of green tea polyphenols in Alzheimer's and Parkinson's diseases.
Topics: Alzheimer Disease; Animals; Antioxidants; Apoptosis; Catechin; Dietary Supplements; Disease Models, Animal; Flavonoids; Gene Expression Regulation; Humans; Iron Chelating Agents; Neuroprotective Agents; Parkinson Disease; Phenols; Polyphenols; Signal Transduction; Tea | 2004 |
Cancer prevention with food factors: alone and in combination.
Topics: Anti-Inflammatory Agents; Anticarcinogenic Agents; Antioxidants; Catechin; Diet; Humans; Tea | 2004 |
Nutraceuticals and cancer management.
Topics: Antioxidants; Capsaicin; Carotenoids; Catechin; Catechols; Complementary Therapies; Curcumin; Fatty Alcohols; Flavones; Genistein; Herbal Medicine; Humans; Isoflavones; Lycopene; Minerals; Neoplasms; Phytoestrogens; Phytotherapy; Plant Preparations; Vitamins | 2005 |
Modulation of P-glycoprotein function and reversal of multidrug resistance by (-)-epigallocatechin gallate in human cancer cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Catechin; Cell Survival; Drug Resistance, Neoplasm; Humans; Tumor Cells, Cultured | 2005 |
Trapping of growth factors by catechins: a possible therapeutical target for prevention of proliferative diseases.
Topics: Animals; Catechin; Cell Proliferation; ErbB Receptors; Growth Substances; Neoplasms; Platelet-Derived Growth Factor; Signal Transduction; Vascular Endothelial Growth Factor A | 2005 |
Green tea: Health benefits as cancer preventive for humans.
Topics: Antineoplastic Agents; Catechin; Epidemiologic Studies; Flavonoids; Humans; Hydrolyzable Tannins; Japan; Neoplasms; Phenols; Polyphenols; Tea; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2005 |
All teas are not created equal: the Chinese green tea and cardiovascular health.
Topics: Animals; Antioxidants; Atherosclerosis; Cardiovascular Diseases; Cardiovascular System; Catechin; Diabetes Mellitus; Endothelium, Vascular; Humans; Metabolic Syndrome; Obesity; Phytotherapy; Plant Extracts; Tea | 2006 |
Medicinal benefits of green tea: Part I. Review of noncancer health benefits.
Topics: Antioxidants; Arthritis; Bone Density; Catechin; Drug Synergism; Free Radical Scavengers; Heart Diseases; Humans; Neuroprotective Agents; Oxidation-Reduction; Plant Extracts; Stress, Psychological; Tea; Weight Loss | 2005 |
Modulation of signal transduction by tea catechins and related phytochemicals.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Capsaicin; Catechin; Curcumin; Genistein; Humans; Molecular Structure; Protein Kinases; Resveratrol; Signal Transduction; Stilbenes; Tea; Transcription Factors | 2005 |
Regulation of gene transcription by botanicals: novel regulatory mechanisms.
Topics: Animals; Bridged Bicyclo Compounds; Catechin; Gene Expression Regulation; Glycine max; Humans; Isoflavones; Peroxisome Proliferator-Activated Receptors; Phloroglucinol; Plants; Pregnane X Receptor; Proteasome Endopeptidase Complex; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Resveratrol; Sirtuins; Stilbenes; Terpenes; Transcription, Genetic; Ubiquitin | 2005 |
Breaking the relay in deregulated cellular signal transduction as a rationale for chemoprevention with anti-inflammatory phytochemicals.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Catechin; Diet; Humans; Inflammation; Molecular Structure; Neoplasms; Plants; Protein Kinases; Signal Transduction; Transcription Factors | 2005 |
Novel treatments for obesity and osteoporosis: targeting apoptotic pathways in adipocytes.
Topics: Adipocytes; Adrenergic beta-Agonists; Animals; Anti-Obesity Agents; Apoptosis; Bone Marrow; Catechin; Cell Differentiation; Ciliary Neurotrophic Factor; Disulfides; Flavonoids; Humans; Leptin; Linoleic Acid; Mesenchymal Stem Cells; Obesity; Osteoporosis; Plant Extracts; Sulfoxides; Tumor Necrosis Factor-alpha | 2005 |
Redox-sensitive transcription factors as prime targets for chemoprevention with anti-inflammatory and antioxidative phytochemicals.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Catechin; Humans; Inflammation; Mice; Neoplasms; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Plant Extracts; Signal Transduction | 2005 |
Opposing action of curcumin and green tea polyphenol in human keratinocytes.
Topics: Antioxidants; Catechin; Cell Differentiation; Chemoprevention; Curcumin; Flavonoids; Gene Expression; Humans; Keratinocytes; p38 Mitogen-Activated Protein Kinases; Phenols; Polyphenols; Protein Precursors; Signal Transduction; Tea | 2006 |
Tea, obesity, and diabetes.
Topics: Adipocytes; Animals; Apoptosis; Body Weight; Catechin; Cell Differentiation; Cell Division; Diabetes Mellitus; Eating; Energy Metabolism; Fatty Acids; Hormones; Humans; Lipids; Lipolysis; Obesity; Oxidation-Reduction; Receptors, Laminin; Tea | 2006 |
Possible mechanisms of the cancer-preventive activities of green tea.
Topics: Animals; Caffeine; Catechin; DNA Modification Methylases; Enzyme Inhibitors; Humans; Neoplasms; Protein Kinase Inhibitors; Protein Kinases; Tea; Telomerase; Tetrahydrofolate Dehydrogenase | 2006 |
Beneficial effects of tea and its polyphenols against prostate cancer.
Topics: Androgens; Animals; Apoptosis; Catechin; Cell Cycle; Clinical Trials as Topic; Fermentation; Flavonoids; Gene Expression; Humans; Male; Neoplasm Transplantation; Neovascularization, Pathologic; Phenols; Polyamines; Polyphenols; Prostate-Specific Antigen; Prostatic Neoplasms; Signal Transduction; Tea | 2006 |
Green tea catechins as brain-permeable, natural iron chelators-antioxidants for the treatment of neurodegenerative disorders.
Topics: Animals; Blood-Brain Barrier; Brain; Catechin; Cell Death; Gene Expression; Humans; Hypoxia; Iron; Iron Chelating Agents; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Tea | 2006 |
Intracellular signaling network as a prime chemopreventive target of (-)-epigallocatechin gallate.
Topics: Animals; Antioxidants; Apoptosis; Catechin; Cell Cycle; Cell Division; Chemoprevention; Humans; Inflammation; Metabolic Detoxication, Phase II; Neoplasm Metastasis; Neoplasms; Protein Kinases; Signal Transduction; Tea; Transcription Factors | 2006 |
Tea, hormone-related cancers and endogenous hormone levels.
Topics: Animals; Breast Neoplasms; Catechin; Female; Hormones; Humans; Male; Neoplasms; Ovarian Neoplasms; Prostatic Neoplasms; Risk Factors; Tea | 2006 |
Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Cycle; Clinical Trials as Topic; ErbB Receptors; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Neovascularization, Pathologic; NF-kappa B; Protease Inhibitors; Receptor, IGF Type 1; Signal Transduction; Tea; Vascular Endothelial Growth Factor A | 2006 |
Beneficial effects of green tea--a review.
Topics: Anticarcinogenic Agents; Antihypertensive Agents; Antimutagenic Agents; Antioxidants; Biological Availability; Camellia sinensis; Cardiovascular Diseases; Catechin; Flavonoids; Health Promotion; Humans; Nutritive Value; Obesity; Phenols; Polyphenols; Tea | 2006 |
A new approach to managing oral manifestations of Sjogren's syndrome and skin manifestations of lupus.
Topics: Anti-Inflammatory Agents; Antioxidants; Apoptosis; Camellia sinensis; Catechin; Female; Humans; Lupus Erythematosus, Systemic; Male; MAP Kinase Signaling System; Phytotherapy; Salivary Glands; Sjogren's Syndrome; Tea; Xerostomia | 2006 |
Dietary small molecules and large-scale gene expression studies: an experimental approach for understanding their beneficial effects on the development of malignant and non-malignant proliferative diseases.
Topics: Animals; Aryldialkylphosphatase; Catechin; Dietary Supplements; Gene Expression Regulation; Genomics; Humans; Neoplasms; Nutritional Physiological Phenomena; Proteomics; Signal Transduction | 2006 |
The roles of polyphenols in cancer chemoprevention.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Catechin; Cell Communication; Cyclooxygenase Inhibitors; Diet; Flavonoids; Gap Junctions; Genistein; Humans; Matrix Metalloproteinases; Neoplasms; Oxidative Stress; Phenols; Polyphenols; Prostaglandin-Endoperoxide Synthases; Quercetin; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes | 2006 |
Epigallocatechin-3-gallate (EGCG): chemical and biomedical perspectives.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Catechin; Humans; Molecular Structure; Neoplasms; Skin; Tea | 2006 |
Role of epigallocatechin gallate (EGCG) in the treatment of breast and prostate cancer.
Topics: Anticarcinogenic Agents; Apoptosis; Breast Neoplasms; Catechin; Cell Cycle; Female; Humans; Male; Prostatic Neoplasms; Tea; Urokinase-Type Plasminogen Activator | 2006 |
Lessons learned from Art Pardee in cell cycle, science, and life.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Cycle; Cell Death; Copper; Cyclins; Flavonoids; Gene Expression Regulation; Humans; Molecular Structure; Multiprotein Complexes; Neoplasms; Phenols; Polyphenols; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Research Personnel; Retinoblastoma Protein | 2006 |
Chemopreventive actions of polyphenolic compounds in cancer.
Topics: Animals; Antineoplastic Agents; Catechin; Flavonoids; Humans; Models, Biological; Molecular Structure; Neoplasms; NF-kappa B; Phenols; Polyphenols; Signal Transduction | 2006 |
Mechanisms of cancer prevention by green and black tea polyphenols.
Topics: Animals; Antioxidants; Apoptosis; Arachidonic Acid; Catechin; Cell Cycle; Cell Proliferation; fas Receptor; Flavonoids; Gene Expression; Humans; Lipid Peroxidation; Lipoproteins, LDL; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; NF-kappa B; Nitric Oxide; Oncogenes; Oxidation-Reduction; Phenols; Polyphenols; Proteasome Inhibitors; Reactive Oxygen Species; Receptors, Androgen; Receptors, Aryl Hydrocarbon; Receptors, Growth Factor; Tea; Telomere; Tetrahydrofolate Dehydrogenase | 2006 |
Green tea polyphenols in the prevention of colon cancer.
Topics: Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Catechin; Clinical Trials, Phase I as Topic; Colonic Neoplasms; Flavonoids; Humans; Mice; Phenols; Polyphenols; Rats; Tea | 2007 |
Dietary polyphenolic phytochemicals--promising cancer chemopreventive agents in humans? A review of their clinical properties.
Topics: Antineoplastic Agents, Phytogenic; Catechin; Clinical Trials, Phase III as Topic; Curcumin; Dietary Supplements; Flavonoids; Humans; Molecular Structure; Neoplasms; Phenols; Polyphenols | 2007 |
Chemopreventive agents alters global gene expression pattern: predicting their mode of action and targets.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antioxidants; Catechin; Docosahexaenoic Acids; Gene Expression Profiling; Humans; Neoplasms; Retinoids; Selenium | 2006 |
The proteasome as a potential target for novel anticancer drugs and chemosensitizers.
Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Catechin; Clinical Trials as Topic; Curcumin; Drug Resistance, Neoplasm; Drug Therapy, Combination; Genistein; Humans; Neoplasms; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Radiation-Sensitizing Agents; Resveratrol; Stilbenes; Structure-Activity Relationship; Ubiquitin | 2006 |
Green tea extract thermogenesis-induced weight loss by epigallocatechin gallate inhibition of catechol-O-methyltransferase.
Topics: Adipose Tissue, Brown; Animals; Camellia sinensis; Catechin; Catechol O-Methyltransferase Inhibitors; Enzyme Inhibitors; Male; Methylation; Norepinephrine; Plant Extracts; Rats; Thermogenesis; Weight Loss | 2006 |
Neurodegeneration in autoimmune demyelination: recent mechanistic insights reveal novel therapeutic targets.
Topics: Acyl Coenzyme A; Animals; Catechin; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Humans; Multiple Sclerosis; Nerve Degeneration; Neuroprotective Agents; T-Lymphocytes; TNF-Related Apoptosis-Inducing Ligand | 2007 |
Tea and cancer prevention: molecular mechanisms and human relevance.
Topics: Animals; Anticarcinogenic Agents; Caffeine; Catechin; Humans; Molecular Structure; Neoplasms; Tea | 2007 |
Green tea as inhibitor of the intestinal absorption of lipids: potential mechanism for its lipid-lowering effect.
Topics: Animals; Catechin; Intestinal Absorption; Lipase; Lipid Metabolism; Micelles; Pancreas; Phospholipases A; Rats; Tea | 2007 |
Proposed mechanisms of (-)-epigallocatechin-3-gallate for anti-obesity.
Topics: Adipocytes; AMP-Activated Protein Kinases; Animals; Antioxidants; Catechin; Extracellular Signal-Regulated MAP Kinases; Humans; Multienzyme Complexes; Obesity; Plant Extracts; Protein Serine-Threonine Kinases; Tea | 2007 |
Matrix proteases, green tea, and St. John's wort: biomedical research catches up with folk medicine.
Topics: Animals; Anti-Inflammatory Agents; Bridged Bicyclo Compounds; Catechin; Humans; Hypericum; Matrix Metalloproteinases; Neovascularization, Pathologic; Phloroglucinol; Pulmonary Fibrosis; Tea; Terpenes | 2007 |
Keratinocyte proliferation, differentiation, and apoptosis--differential mechanisms of regulation by curcumin, EGCG and apigenin.
Topics: Anticarcinogenic Agents; Apigenin; Apoptosis; Catechin; Cell Differentiation; Cell Proliferation; Curcumin; Humans; Keratinocytes; Protein Kinases | 2007 |
Reading the tea leaves: anticarcinogenic properties of (-)-epigallocatechin-3-gallate.
Topics: Anticarcinogenic Agents; Antioxidants; Catechin; Cell Cycle; Confounding Factors, Epidemiologic; Humans; Neoplasms; Tea | 2007 |
Green tea polyphenols: biology and therapeutic implications in cancer.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Cycle; Cell Proliferation; Flavonoids; Gene Expression Regulation; Humans; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Phenols; Polyphenols; Signal Transduction; Tea | 2007 |
Inhibition of carcinogenesis by tea constituents.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Transformation, Neoplastic; Disease Models, Animal; Flavonoids; Humans; Neoplasms; Phenols; Polyphenols; Tea | 2007 |
Predicting the physiological relevance of in vitro cancer preventive activities of phytochemicals.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Catechin; Curcumin; Humans; Indoles; Neoplasms; Resveratrol; Stilbenes | 2007 |
Cancer preventive mechanisms of the green tea polyphenol (-)-epigallocatechin-3-gallate.
Topics: Anticarcinogenic Agents; Catechin; Humans; Mitogen-Activated Protein Kinases; Neoplasms; NF-kappa B; Signal Transduction; Tea; Transcription Factor AP-1 | 2007 |
[Effect of green tea flavonols on the function of the endoplasmic reticulum].
Topics: alpha-Glucosidases; Animals; Antineoplastic Agents; Apoptosis; Blood Glucose; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Endoplasmic Reticulum; Flavonols; Glucuronides; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Liver; Liver Neoplasms; Microsomes; Tea | 2007 |
Effects of flavonoid-containing beverages and EGCG on endothelial function.
Topics: Antioxidants; Atherosclerosis; Beverages; Cardiovascular Diseases; Catechin; Endothelium, Vascular; Flavonoids; Humans; Risk Factors | 2007 |
Effects of green tea and EGCG on cardiovascular and metabolic health.
Topics: Animals; Blood Pressure; Cardiovascular Diseases; Catechin; Dose-Response Relationship, Drug; Endothelium, Vascular; Energy Metabolism; Humans; Insulin Resistance; Obesity; Tea | 2007 |
Cell cycle control as a basis for cancer chemoprevention through dietary agents.
Topics: Animals; Anticarcinogenic Agents; Apigenin; Catechin; Cell Cycle; Cell Proliferation; Curcumin; Cyclin-Dependent Kinases; Diet; Genistein; Humans; Neoplasms; Resveratrol; Silymarin; Stilbenes; Tea | 2008 |
Putative cancer chemopreventive agents of dietary origin-how safe are they?
Topics: Antineoplastic Agents, Phytogenic; Capsaicin; Catechin; Chemoprevention; Consumer Product Safety; Curcumin; Diet; Humans; Indoles; Male; Neoplasms; Quercetin; Toxicity Tests | 2007 |
Targeting multiple Alzheimer's disease etiologies with multimodal neuroprotective and neurorestorative iron chelators.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Catechin; Cell Cycle; Humans; Hydroxyquinolines; Iron; Iron Chelating Agents; Neurodegenerative Diseases; Neuroprotective Agents; PC12 Cells; Piperazines; Rats | 2008 |
Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG.
Topics: Animals; Antioxidants; Biotransformation; Catechin; Enzyme Induction; Humans; Inactivation, Metabolic; NF-E2-Related Factor 2; Tea | 2008 |
Relevance of the concept of oncogene addiction to hormonal carcinogenesis and molecular targeting in cancer prevention and therapy.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Catechin; Female; Humans; Male; Neoplasms, Hormone-Dependent; Oncogenes; Prostatic Neoplasms; Sulindac | 2008 |
Multitargeted therapy of cancer by green tea polyphenols.
Topics: Anticarcinogenic Agents; Apoptosis; Biological Availability; Catechin; Cell Cycle; ErbB Receptors; Flavonoids; Humans; Insulin-Like Growth Factor I; MAP Kinase Signaling System; Matrix Metalloproteinase Inhibitors; Neoplasms; NF-kappa B; Phenols; Polyphenols; Signal Transduction; Tea; Transcription Factor AP-1; Urokinase-Type Plasminogen Activator | 2008 |
Suppression of cancer invasiveness by dietary compounds.
Topics: Animals; Antineoplastic Agents; Catechin; Drugs, Chinese Herbal; Genistein; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Reishi; Signal Transduction; Structure-Activity Relationship; Tea | 2008 |
Reversal of hypermethylation and reactivation of genes by dietary polyphenolic compounds.
Topics: Animals; Catechin; Cell Line, Tumor; Diet; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Epigenesis, Genetic; Flavonoids; Humans; Phenols; Polyphenols | 2008 |
The Bmi-1 polycomb group gene in skin cancer: regulation of function by (-)-epigallocatechin-3-gallate.
Topics: Animals; Anticarcinogenic Agents; Catechin; Diet; Epidermis; Epigenesis, Genetic; Humans; Mice; Nuclear Proteins; Polycomb Repressive Complex 1; Proto-Oncogene Proteins; Repressor Proteins; Skin Neoplasms; Tea | 2008 |
Green tea catechins and cardiovascular health: an update.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood Platelets; Cardiovascular Diseases; Cardiovascular System; Catechin; Cell Proliferation; Endothelial Cells; Humans; Inflammation; Lipids; Models, Chemical; Oxidative Stress; Tea | 2008 |
Green tea polyphenol EGCG signaling pathway through the 67-kDa laminin receptor.
Topics: Animals; Apoptosis; Camellia sinensis; Catechin; Cell Division; Eukaryotic Initiation Factor-1; Histamine Release; Humans; Neoplasms; Receptors, IgE; Receptors, Laminin; Signal Transduction | 2008 |
The challenge of developing green tea polyphenols as therapeutic agents.
Topics: Biological Availability; Biotransformation; Catechin; Humans; Structure-Activity Relationship; Tea | 2008 |
Green tea polyphenols as a natural tumour cell proteasome inhibitor.
Topics: Anticarcinogenic Agents; Catechin; Methylation; Proteasome Inhibitors; Tea; Ubiquitin | 2008 |
Untangling the glutamate dehydrogenase allosteric nightmare.
Topics: Allosteric Regulation; Animals; Catechin; Ciliophora; Enzyme Activation; Evolution, Molecular; Glutamate Dehydrogenase; Humans; Insulin; Insulin Secretion; Models, Molecular | 2008 |
Cell signaling pathways and iron chelation in the neurorestorative activity of green tea polyphenols: special reference to epigallocatechin gallate (EGCG).
Topics: Alzheimer Disease; Catechin; Flavonoids; Humans; Iron Chelating Agents; Neurodegenerative Diseases; Nootropic Agents; Phenols; Polyphenols; Signal Transduction; Tea | 2008 |
Simultaneous manipulation of multiple brain targets by green tea catechins: a potential neuroprotective strategy for Alzheimer and Parkinson diseases.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antioxidants; Brain; Catechin; Cells, Cultured; Humans; Hypoxia-Inducible Factor 1; Iron; Neuroprotective Agents; Parkinson Disease; Protein Kinase C | 2008 |
Phytochemicals as potential chemopreventive and chemotherapeutic agents in hepatocarcinogenesis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Brassicaceae; Caffeine; Capsaicin; Carcinoma, Hepatocellular; Catechin; Chemoprevention; Curcumin; Flavonoids; Humans; Liver Neoplasms; Phenols; Plant Extracts; Polyphenols; Resveratrol; Stilbenes | 2009 |
[Progress in the studies on small molecule IGF-1R inhibitors].
Topics: Animals; Apoptosis; Benzimidazoles; Catechin; Cell Line, Tumor; Humans; Neoplasms; Piperazines; Protein Kinase Inhibitors; Pyridones; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Signal Transduction | 2008 |
Comparative neuroprotective properties of stilbene and catechin analogs: action via a plasma membrane receptor site?
Topics: Amyloid beta-Peptides; Autoradiography; Catechin; Cell Membrane; Flavonoids; Neuroprotective Agents; Phenols; Polyphenols; Prealbumin; Protein Kinase C-delta; Resveratrol; Stilbenes; Structure-Activity Relationship; Tea | 2009 |
Molecular targets of (-)-epigallocatechin-3-gallate (EGCG): specificity and interaction with membrane lipid rafts.
Topics: Animals; Antineoplastic Agents; Apoptosis; Camellia sinensis; Catechin; Drug Delivery Systems; Humans; Membrane Microdomains; Mitogen-Activated Protein Kinases; Neoplasms; Tea | 2008 |
Cellular signaling perturbation by natural products.
Topics: Antineoplastic Agents; Carotenoids; Catechin; Curcumin; Humans; Indoles; Isoflavones; Lycopene; Neoplasms; Resveratrol; Signal Transduction; Stilbenes | 2009 |
Chemoprotective mechanism of the natural compounds, epigallocatechin-3-O-gallate, quercetin and curcumin against cancer and cardiovascular diseases.
Topics: Anticarcinogenic Agents; Antioxidants; Cardiovascular Diseases; Catechin; Curcumin; Humans; Models, Biological; Molecular Structure; Neoplasms; Oxidative Stress; Quercetin | 2009 |
Molecular basis for cancer chemoprevention by green tea polyphenol EGCG.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Catechin; Chemoprevention; Flavonoids; Humans; Mice; Neoplasms; Phenols; Polyphenols; Receptors, Laminin; Tea | 2009 |
Chemoprevention with phytochemicals targeting inducible nitric oxide synthase.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antioxidants; Benzyl Alcohols; Catechin; Chemoprevention; Coumarins; Curcumin; Flavones; Mice; Nitric Oxide Synthase Type II; Rats; Resveratrol; Sesquiterpenes; Stilbenes | 2009 |
Green tea: nature's defense against malignancies.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antioxidants; Apoptosis; Camellia sinensis; Catechin; Cell Division; DNA Repair; Flavonoids; Free Radical Scavengers; Humans; Immunity; Immunologic Factors; Oxidative Stress; Phenols; Plant Leaves; Polyphenols; Tea | 2009 |
[Green tea polyphenol receptor and the signaling pathway].
Topics: Anti-Allergic Agents; Antineoplastic Agents; Catechin; Humans; Receptors, Laminin; Signal Transduction; Tea | 2009 |
Epigallocatechin 3-gallate and green tea catechins: United they work, divided they fail.
Topics: Adenoma; Aerosols; Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Biological Availability; Catechin; Cell Line, Tumor; Drug Screening Assays, Antitumor; Drug Synergism; Flavonoids; Humans; Lung Neoplasms; Mice; Mice, Inbred A; Models, Biological; Neoplasms; Phenols; Phytotherapy; Polyphenols; Protein Binding; Tea | 2009 |
Cancer prevention by tea: animal studies, molecular mechanisms and human relevance.
Topics: Animals; Anticarcinogenic Agents; Catechin; Humans; Neoplasms; Phytotherapy; Plant Extracts; Tea | 2009 |
Green tea and prostate cancer: from bench to clinic.
Topics: Animals; Anticarcinogenic Agents; Camellia sinensis; Catechin; Humans; Male; Mice; Phytotherapy; Plant Extracts; Prostatic Neoplasms; Signal Transduction | 2009 |
Dietary chemopreventive phytochemicals: too little or too much?
Topics: Animals; Catechin; Cell Transformation, Neoplastic; Curcumin; Diet; Food; Fruit; Genistein; Humans; Indoles; Mice; Models, Biological; Neoplasms; Phytotherapy; Vegetables | 2009 |
Green tea (Camellia sinensis) catechins and vascular function.
Topics: Animals; Atherosclerosis; Biological Availability; Blood Vessels; Camellia sinensis; Cardiovascular Diseases; Cardiovascular Physiological Phenomena; Catechin; Endothelium, Vascular; Flavonoids; Homeostasis; Humans; Phenols; Phytotherapy; Polyphenols; Signal Transduction; Tea | 2009 |
Clusterin (CLU) and prostate cancer.
Topics: Animals; Catechin; Cell Line, Transformed; Clusterin; Cyclooxygenase 2 Inhibitors; Genes, Tumor Suppressor; Humans; Male; Neoplasm Metastasis; Prostatic Neoplasms; Signal Transduction | 2009 |
Skin photoprotection by natural polyphenols: anti-inflammatory, antioxidant and DNA repair mechanisms.
Topics: Anti-Inflammatory Agents; Antioxidants; Catechin; Dermatitis; DNA Damage; DNA Repair; Flavonoids; Humans; Neoplasms, Radiation-Induced; Phenols; Polyphenols; Skin; Skin Neoplasms; Sunscreening Agents; Tea; Ultraviolet Rays | 2010 |
Apoptosis by dietary agents for prevention and treatment of prostate cancer.
Topics: Adenocarcinoma; Aged; Animals; Apoptosis; Carotenoids; Catechin; Clinical Trials as Topic; Curcumin; Drug Screening Assays, Antitumor; Flavonoids; Flavonols; Genistein; Humans; Lycopene; Lythraceae; Male; Mice; Mice, Nude; Mice, Transgenic; Middle Aged; Neoplasm Proteins; Pentacyclic Triterpenes; Phytotherapy; Plant Extracts; Prostatic Neoplasms; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2010 |
Targeting polyamines and biogenic amines by green tea epigallocatechin-3-gallate.
Topics: Animals; Biogenic Amines; Biogenic Polyamines; Biosynthetic Pathways; Camellia sinensis; Catechin; Humans; Plant Extracts; Tea | 2010 |
Green tea polyphenols for prostate cancer chemoprevention: a translational perspective.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Camellia sinensis; Catechin; Cell Survival; Flavonoids; Humans; Male; Phenols; Phytotherapy; Plant Extracts; Polyphenols; Prostatic Neoplasms; Tea | 2010 |
Polyphenols: biological activities, molecular targets, and the effect of methylation.
Topics: Anticarcinogenic Agents; Catechin; Flavonoids; Humans; Methylation; Phenols; Polyphenols; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Ubiquitin | 2008 |
Naturally occurring phytochemicals for the prevention of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Catechin; Cognition Disorders; Curcumin; Dietary Supplements; Humans; Oxidative Stress; Phytotherapy; Plant Extracts; Resveratrol; Stilbenes | 2010 |
Review: green tea polyphenols in chemoprevention of prostate cancer: preclinical and clinical studies.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Catechin; Disease Progression; Flavonoids; Humans; Male; Phenols; Polyphenols; Prostatic Neoplasms; Risk Factors; Tea | 2009 |
Merging traditional Chinese medicine with modern drug discovery technologies to find novel drugs and functional foods.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antimalarials; Artemisinins; Catechin; Diterpenes; Drug Discovery; Drugs, Chinese Herbal; Epoxy Compounds; Functional Food; Humans; Medicine, Chinese Traditional; Phenanthrenes | 2010 |
[New perspectives on molecular and genic therapies in Down syndrome].
Topics: Animals; Catechin; Chromosomes, Human, Pair 21; Disease Models, Animal; Down Syndrome; Droxidopa; Drug Delivery Systems; Fluoxetine; Forecasting; Gene Expression Regulation; Genetic Association Studies; Genetic Therapy; Hedgehog Proteins; Humans; Memantine; Mice; Mice, Transgenic; Models, Genetic; Neuronal Plasticity; Neurotransmitter Agents; Pentylenetetrazole; Phenotype; Signal Transduction | 2010 |
Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Catechin; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Genistein; Humans; Isothiocyanates; Neoplasms; Selenium | 2010 |
Green tea polyphenol epigallocatechin 3-gallate in arthritis: progress and promise.
Topics: Animals; Antioxidants; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Camellia sinensis; Catechin; Humans; Osteoarthritis; Plant Extracts; Tea; Treatment Outcome | 2010 |
Green tea polyphenol epigallocatechin-3-gallate: inflammation and arthritis. [corrected].
Topics: Arthritis; Catechin; Flavonoids; Humans; Inflammation; Phenols; Polyphenols; Structure-Activity Relationship; Tea | 2010 |
The antioxidant and pro-oxidant activities of green tea polyphenols: a role in cancer prevention.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis; Catalysis; Catechin; Cell Proliferation; Chelating Agents; Flavonoids; Humans; Models, Biological; Neoplasms; Oxidants; Oxidation-Reduction; Phenols; Polyphenols; Signal Transduction; Tea; Trace Elements | 2010 |
Targeting of histamine producing cells by EGCG: a green dart against inflammation?
Topics: Anti-Inflammatory Agents; Basophils; Catechin; Histamine; Humans; Inflammation; Macrophages; Megakaryocytes; Monocytes; Neurons; Tea | 2010 |
Green tea extract-patents and diversity of uses.
Topics: Camellia sinensis; Catechin; Humans; Patents as Topic; Phytotherapy; Plant Extracts; Tea | 2009 |
Chemoprevention of head and neck cancer with green tea polyphenols.
Topics: Animals; Carcinoma, Squamous Cell; Catechin; Chemoprevention; Flavonoids; Head and Neck Neoplasms; Humans; Models, Biological; Phenols; Plant Extracts; Polyphenols; Tea | 2010 |
Use of STAT1 inhibitors in the treatment of brain I/R injury and neurodegenerative diseases.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Catechin; Humans; Janus Kinases; Molecular Structure; Neurodegenerative Diseases; Neuroprotective Agents; Phloroglucinol; Reperfusion Injury; Signal Transduction; STAT1 Transcription Factor; Terpenes | 2011 |
Nanochemoprevention: sustained release of bioactive food components for cancer prevention.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Proliferation; Delayed-Action Preparations; Humans; Nanocapsules; Nanoparticles; Neoplasms | 2010 |
Green tea and cancer prevention.
Topics: Animals; Anticarcinogenic Agents; Catechin; Enzyme Inhibitors; Humans; Neoplasms; Tea | 2010 |
Chemopreventive potential of natural compounds in head and neck cancer.
Topics: Animals; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Catechin; Curcumin; Cyclooxygenase 2 Inhibitors; ErbB Receptors; Head and Neck Neoplasms; Humans; NF-kappa B; Resveratrol; Stilbenes; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53 | 2010 |
[Progress in the study of heat shock protein 90 inhibitors].
Topics: Adenine; Animals; Anisoles; Antineoplastic Agents; Benzoquinones; Catechin; Cell Line, Tumor; Crystallization; Heterocyclic Compounds, 2-Ring; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Macrolides; Molecular Structure; Neoplasms; Pyrazoles; Structure-Activity Relationship | 2010 |
[Ingredients with vasodilator effect. Effect of green tea on the formation of endothelin-1].
Topics: Catechin; Endothelin-1; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Oncogene Protein v-akt; Phosphorylation; Tea; Vasodilator Agents | 2010 |
Role of flavonoids in intestinal tight junction regulation.
Topics: Animals; Antioxidants; Catechin; Diet; Flavonoids; Genistein; Humans; Intestinal Mucosa; Membrane Proteins; Phosphorylation; Quercetin; Tight Junctions | 2011 |
Weight control and prevention of metabolic syndrome by green tea.
Topics: Animals; Body Weight; Catechin; Flavonoids; Humans; Metabolic Syndrome; Phenols; Polyphenols; Tea | 2011 |
New cancer treatment strategy using combination of green tea catechins and anticancer drugs.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Catechin; Humans; Neoplasms; Phytotherapy; Plant Extracts; Tea | 2011 |
Targeting cell signaling and apoptotic pathways by dietary agents: role in the prevention and treatment of cancer.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Catechin; Clinical Trials as Topic; Curcuma; Curcumin; Diet; Disease Models, Animal; Fruit; Genistein; Humans; Neoplasms; Resveratrol; Signal Transduction; Silymarin; Stilbenes; United States; Vegetables | 2011 |
Implications of cancer stem cell theory for cancer chemoprevention by natural dietary compounds.
Topics: Alkaloids; Animals; Anticarcinogenic Agents; Benzodioxoles; beta Catenin; Carotenoids; Catechin; Cell Differentiation; Cell Proliferation; Cholecalciferol; Curcumin; Diet; Humans; Isoflavones; Isothiocyanates; Lycopene; Neoplasms; Neoplastic Stem Cells; Piperidines; Polyunsaturated Alkamides; Resveratrol; Signal Transduction; Stilbenes; Sulfoxides; Thiocyanates; Wnt Proteins | 2011 |
Maintenance therapy for B-chronic lymphocytic leukemia.
Topics: Antibodies, Monoclonal, Murine-Derived; Catechin; Curcumin; Humans; Lenalidomide; Leukemia, Lymphocytic, Chronic, B-Cell; Rituximab; Thalidomide | 2011 |
Inhibitors of microglial neurotoxicity: focus on natural products.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzyl Alcohols; Biological Products; Biphenyl Compounds; Catechin; Catechols; Curcumin; Encephalitis; Fatty Alcohols; Ginsenosides; Glucosides; Microglia; Molecular Structure; Nerve Degeneration; Neuroprotective Agents; Phenyl Ethers; Plant Extracts; Resveratrol; Stilbenes | 2011 |
Polyphenols: planting the seeds of treatment for the metabolic syndrome.
Topics: Animals; Antioxidants; Catechin; Curcumin; Flavonoids; Humans; Metabolic Syndrome; Phenols; Plant Extracts; Polyphenols; Quercetin; Resveratrol; Stilbenes | 2011 |
EGCG, green tea polyphenols and their synthetic analogs and prodrugs for human cancer prevention and treatment.
Topics: Anticarcinogenic Agents; Catechin; DNA Damage; DNA Methylation; Flavonoids; Humans; Neoplasms; Phenols; Polyphenols; Prodrugs; Proteasome Inhibitors; Structure-Activity Relationship; Tea | 2011 |
Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antioxidants; Apoptosis; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Diet; Flavonoids; Fruit; Humans; Phenols; Polyphenols; Propiophenones; Quercetin; Resveratrol; Rutin; Stilbenes; Vegetables | 2011 |
Green tea polyphenol sensing.
Topics: Animals; Catechin; Humans; Hypersensitivity; Inflammation; Neoplasms; Receptors, Laminin; Tea | 2011 |
Dietary flavonoids as cancer prevention agents.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Cycle; Curcumin; Diet; Flavonoids; Food; Humans; Isothiocyanates; Neovascularization, Pathologic; Signal Transduction | 2011 |
Configurational studies of complexes of tea catechins with caffeine and various cyclodextrins.
Topics: Caffeine; Catechin; Crystallography, X-Ray; Cyclodextrins; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Conformation; Stereoisomerism; Tea; Water | 2011 |
Modulation of Nrf2/ARE pathway by food polyphenols: a nutritional neuroprotective strategy for cognitive and neurodegenerative disorders.
Topics: Animals; Antioxidants; Catechin; Cognition Disorders; Curcumin; Diet; Food; Heme Oxygenase-1; Humans; Molecular Structure; Neurodegenerative Diseases; Neuroprotective Agents; NF-E2-Related Factor 2; Polyphenols; Response Elements | 2011 |
Inducing apoptosis in chemotherapy-resistant B-lineage acute lymphoblastic leukaemia cells by targeting HSPA5, a master regulator of the anti-apoptotic unfolded protein response signalling network.
Topics: Adolescent; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Catechin; Child; Child, Preschool; Doxorubicin; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Endoplasmic Reticulum Chaperone BiP; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heat-Shock Proteins; Humans; Infant; Molecular Targeted Therapy; Neoplasm Proteins; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Signal Transduction; Tumor Cells, Cultured; Unfolded Protein Response | 2011 |
Multistage carcinogenesis process as molecular targets in cancer chemoprevention by epicatechin-3-gallate.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Catechin; Humans; Neoplasms; Signal Transduction; Tea | 2011 |
Naturally plant-derived compounds: role in bone anabolism.
Topics: Bone and Bones; Bone Density; Carotenoids; Catechin; Flavonoids; Humans; Lignans; Osteoporosis; Plants; Polyphenols; Signal Transduction; Stilbenes | 2012 |
Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Camellia sinensis; Catechin; Cell Proliferation; Cell Transformation, Neoplastic; Humans; Molecular Structure; Neoplasms; Signal Transduction | 2011 |
The ability of green tea to alleviate autoimmune diseases: fact or fiction?
Topics: Animals; Autoimmune Diseases; Catechin; Humans; Polyphenols; Tea | 2011 |
Epigallocatechin-3-gallate (EGCG) for clinical trials: more pitfalls than promises?
Topics: Antioxidants; Biological Availability; Catechin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Signal Transduction | 2011 |
Green tea EGCG, T cells, and T cell-mediated autoimmune diseases.
Topics: Animals; Autoimmune Diseases; Catechin; CD4-Positive T-Lymphocytes; Cell Differentiation; Humans; Immunity, Cellular; Immunologic Factors; T-Lymphocytes; Tea | 2012 |
Epigenetic diet: impact on the epigenome and cancer.
Topics: Anticarcinogenic Agents; Catechin; Curcumin; Diet; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Epigenomics; Genistein; Histones; Humans; Isothiocyanates; MicroRNAs; Neoplasms; Polyphenols; Resveratrol; Stilbenes; Tea | 2011 |
Phytochemicals in cancer prevention and therapy: truth or dare?
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Carotenoids; Catechin; Curcumin; Genistein; Humans; Isothiocyanates; Lycopene; Neoplasms; Resveratrol; Stilbenes | 2010 |
Tea flavan-3-ols as modulating factors in endoplasmic reticulum function.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Biological Transport; Biotransformation; Calcium Signaling; Carcinogens; Catechin; Drug Resistance, Neoplasm; Endoplasmic Reticulum; Flavonoids; Gluconeogenesis; Glucuronides; Glycosylation; Humans; Hypoglycemic Agents; Protein Processing, Post-Translational; Tea | 2011 |
New insights into the mechanisms of green tea catechins in the chemoprevention of prostate cancer.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Cycle Checkpoints; Cell Proliferation; Humans; Male; NF-kappa B; Prostatic Neoplasms; Proteasome Inhibitors; Tea | 2012 |
Green tea: a promising natural product in oral health.
Topics: Antioxidants; Catechin; Cell Transformation, Neoplastic; Dental Caries; Halitosis; Humans; Inflammation; Influenza, Human; Mouth Neoplasms; Oral Health; Oxidative Stress; Polyphenols; Smoking; Tea | 2012 |
Green tea consumption: an alternative approach to managing oral lichen planus.
Topics: Anticarcinogenic Agents; Antigens; Catechin; Humans; Immunologic Factors; Lichen Planus, Oral; Tea | 2012 |
Natural mood foods: the actions of polyphenols against psychiatric and cognitive disorders.
Topics: Affect; Animals; Antioxidants; Brain; Catechin; Cognition Disorders; Curcumin; Diet; Energy Intake; Energy Metabolism; Food Preferences; Humans; Nervous System Physiological Phenomena; Neurodegenerative Diseases; Oxidative Stress; Polyphenols | 2012 |
Catechins containing a galloyl moiety as potential anti-HIV-1 compounds.
Topics: Anti-HIV Agents; Catechin; Drug Discovery; HIV Infections; HIV-1; Humans; Molecular Structure | 2012 |
Green tea for ovarian cancer prevention and treatment: a systematic review of the in vitro, in vivo and epidemiological studies.
Topics: Animals; Apoptosis; Carcinoma, Ovarian Epithelial; Catechin; Cell Line, Tumor; Cell Movement; Female; Humans; Incidence; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Protective Agents; Tea | 2012 |
Encapsulated nanoepigallocatechin-3-gallate and elemental selenium nanoparticles as paradigms for nanochemoprevention.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cattle; Chemoprevention; Humans; Metal Nanoparticles; Mice; Nanocapsules; Nanomedicine; Neoplasms; Selenium; Selenoproteins; Serum Albumin, Bovine | 2012 |
Green tea: an effective synergist with anticancer drugs for tertiary cancer prevention.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Catechin; Cell Line, Tumor; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasms; Receptors, TNF-Related Apoptosis-Inducing Ligand; Tea; TNF-Related Apoptosis-Inducing Ligand; Transcription Factor CHOP; Tumor Burden; Xenograft Model Antitumor Assays | 2012 |
Pleiotropic protective effects of phytochemicals in Alzheimer's disease.
Topics: Alzheimer Disease; Catechin; Curcumin; Humans; Neuroprotective Agents; NF-E2-Related Factor 2; Polyphenols; Resveratrol; Stilbenes | 2012 |
Polyphenols: key issues involved in chemoprevention of prostate cancer.
Topics: Antioxidants; Catechin; Curcumin; Flavonoids; Genistein; Humans; Male; Polyphenols; Prostatic Neoplasms; Quercetin; Resveratrol; Stilbenes | 2012 |
Cancer stem cells: potential target for bioactive food components.
Topics: Alkaloids; Benzodioxoles; Catechin; Cell Differentiation; Cell Proliferation; Choline; Curcumin; Cyclin-Dependent Kinase 6; Diet; Epigenesis, Genetic; Gene Expression Regulation; Genistein; Glutamates; Humans; Intercellular Signaling Peptides and Proteins; Isothiocyanates; Membrane Proteins; Mesenchymal Stem Cells; Neoplastic Stem Cells; Nuclear Proteins; Piperidines; Plant Extracts; Polycomb Repressive Complex 1; Polyunsaturated Alkamides; Proto-Oncogene Proteins; Repressor Proteins; STAT1 Transcription Factor; Sulfoxides; Thiocyanates; Vitamin A; Vitamin D; Wnt Proteins | 2012 |
Dietary polyphenols and mechanisms of osteoarthritis.
Topics: Cartilage, Articular; Catechin; Citrus; Curcumin; Flavones; Genistein; Humans; Lythraceae; Osteoarthritis; Plant Extracts; Polyphenols; Resveratrol; Stilbenes | 2012 |
Dietary polyphenol-derived protection against neurotoxic β-amyloid protein: from molecular to clinical.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Catechin; Cell Line; Curcumin; Diet; Humans; Models, Molecular; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Plants; Polyphenols; Resveratrol; Stilbenes; Tea | 2012 |
Anti-infective properties of epigallocatechin-3-gallate (EGCG), a component of green tea.
Topics: Animals; Anti-Infective Agents; Catechin; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Tea; Viruses | 2013 |
Recent advances in the design, synthesis, and biological evaluation of selective DYRK1A inhibitors: a new avenue for a disease modifying treatment of Alzheimer's?
Topics: Alzheimer Disease; Animals; Anthraquinones; Biomedical Research; Carbolines; Catechin; Chromosomes, Human, Pair 21; Coumarins; Down Syndrome; Drug Design; Dyrk Kinases; Humans; Mice; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; tau Proteins | 2012 |
Novel epigallocatechin gallate analogs as potential anticancer agents: a patent review (2009 - present).
Topics: Animals; Antineoplastic Agents, Phytogenic; Catechin; Drug Design; Humans; Molecular Structure; Patents as Topic; Structure-Activity Relationship | 2013 |
[Anti-cancer properties epigallocatechin-gallate contained in green tea].
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Breast Neoplasms; Catechin; Cell Transformation, Neoplastic; Female; Gastrointestinal Neoplasms; Humans; Male; Neoplasms; Skin Neoplasms; Tea | 2013 |
Chemopreventive and therapeutic potential of tea polyphenols in hepatocellular cancer.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antioxidants; Biological Availability; Catechin; Chemoprevention; Disease Models, Animal; Humans; Liver Neoplasms; Mice; Polyphenols; Tea; Xenograft Model Antitumor Assays | 2013 |
Nutraceuticals as new treatment approaches for oral cancer: II. Green tea extracts and resveratrol.
Topics: Animals; Catechin; Dietary Supplements; Humans; Mice; Mouth Neoplasms; Plant Extracts; Resveratrol; Stilbenes; Tea | 2013 |
Molecular pathways to polyglutamine aggregation.
Topics: Amyloid; Catechin; Cellular Microenvironment; Humans; Oligopeptides; Peptides; Protein Binding; Protein Folding; Protein Interaction Domains and Motifs; Proteostasis Deficiencies; Small Molecule Libraries; Solutions | 2012 |
Green tea polyphenol epigallocatechin-3-gallate (EGCG) as adjuvant in cancer therapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Catechin; Cell Cycle; Chemotherapy, Adjuvant; Humans; Neoplasms; Neovascularization, Pathologic; Polyphenols; Tea | 2013 |
Epigenetic impact of dietary isothiocyanates in cancer chemoprevention.
Topics: Animals; Anticarcinogenic Agents; Brassica; Catechin; Chemoprevention; Diet; DNA Methylation; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; MicroRNAs; Neoplasms; NF-E2-Related Factor 2; Signal Transduction; Sulfoxides | 2013 |
Natural compounds may open new routes to treatment of amyloid diseases.
Topics: Amyloid; Animals; Catechin; Humans; Models, Molecular; Neuroprotective Agents; Proteostasis Deficiencies | 2013 |
Tumor promoters: from chemicals to inflammatory proteins.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Catechin; Gastrointestinal Neoplasms; Helicobacter Infections; Humans; Inflammation; Inflammation Mediators; Neoplasms, Experimental; Okadaic Acid; Organ Specificity; Skin Neoplasms | 2013 |
Regulating miRNA by natural agents as a new strategy for cancer treatment.
Topics: Animals; Antineoplastic Agents; Carotenoids; Catechin; Curcumin; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Lycopene; MicroRNAs; Molecular Targeted Therapy; Neoplasms; Neoplastic Stem Cells; Resveratrol; Stilbenes | 2013 |
Drug-delivery systems of green tea catechins for improved stability and bioavailability.
Topics: Animals; Biological Availability; Catechin; Drug Carriers; Emulsions; Humans; Liposomes; Nanoparticles; Polymers; Tea | 2013 |
Immunomodulating effects of epigallocatechin-3-gallate from green tea: mechanisms and applications.
Topics: Animals; Autoimmune Diseases; Catechin; CD4-Positive T-Lymphocytes; Cell Differentiation; Cell Proliferation; Humans; Immune System; Immunity, Innate; Immunomodulation; Models, Animal; Tea | 2013 |
Chemopreventive potential of flavonoids in oral squamous cell carcinoma in human studies.
Topics: Administration, Mucosal; Anticarcinogenic Agents; Catechin; Chemoprevention; Drug Delivery Systems; Flavonoids; Fruit; Humans; Mouth Neoplasms; Nanoparticles; Polyphenols; Randomized Controlled Trials as Topic; Tea | 2013 |
Delivering flavonoids into solid tumors using nanotechnologies.
Topics: Animals; Antineoplastic Agents; Biological Availability; Catechin; Drug Delivery Systems; Flavonoids; Genistein; Humans; Nanotechnology; Neoplasms; Quercetin | 2013 |
Potential benefits of green tea polyphenol EGCG in the prevention and treatment of vascular inflammation in rheumatoid arthritis.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Atherosclerosis; Catechin; Complementary Therapies; Cytokines; Humans; Inflammation; Tea | 2013 |
Medicinal chemistry of the epigenetic diet and caloric restriction.
Topics: Aging; Anticarcinogenic Agents; Caloric Restriction; Catechin; Chemistry, Pharmaceutical; Curcumin; Epigenesis, Genetic; Humans; Isothiocyanates; Resveratrol; Stilbenes; Sulfoxides | 2013 |
Effect of green tea catechins on breast carcinogenesis: a systematic review of in-vitro and in-vivo experimental studies.
Topics: Animals; Breast Neoplasms; Carcinogenesis; Catechin; Cells, Cultured; Female; Flavonoids; Humans; Plant Extracts; Tea | 2014 |
Catechin prodrugs and analogs: a new array of chemical entities with improved pharmacological and pharmacokinetic properties.
Topics: Antineoplastic Agents, Phytogenic; Catechin; Drug Delivery Systems; Molecular Structure; Tea | 2013 |
Polyphenols: benefits to the cardiovascular system in health and in aging.
Topics: Aging; Animals; Cardiovascular System; Catechin; Curcumin; Diet; Disease Models, Animal; Fruit; Heart Diseases; Humans; Olive Oil; Plant Oils; Polyphenols; Quercetin; Randomized Controlled Trials as Topic; Reactive Oxygen Species; Resveratrol; Stilbenes | 2013 |
Potential effects of medicinal plants and secondary metabolites on acute lung injury.
Topics: Acute Lung Injury; Adrenal Cortex Hormones; Capillary Permeability; Catechin; Ginkgo biloba; Humans; Lung; Plant Extracts; Plants, Medicinal; Secondary Metabolism | 2013 |
Epigenetic effects of green tea polyphenols in cancer.
Topics: Animals; Bone Morphogenetic Protein 2; Catechin; CDX2 Transcription Factor; Diet; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Neoplasms; Polyphenols; Tea; Trans-Activators | 2013 |
Novel insights of dietary polyphenols and obesity.
Topics: Adipocytes; Animals; Catechin; Cell Differentiation; Curcumin; Diet; Humans; Obesity; Plant Extracts; Polyphenols; Randomized Controlled Trials as Topic; Resveratrol; Stilbenes; Tea | 2014 |
Downstream carcinogenesis signaling pathways by green tea polyphenols: a translational perspective of chemoprevention and treatment for cancers.
Topics: Animals; Anticarcinogenic Agents; Camellia sinensis; Carcinogenesis; Catechin; Humans; Neoplasms; Polyphenols; Signal Transduction | 2014 |
Understanding amyloid fibril nucleation and aβ oligomer/drug interactions from computer simulations.
Topics: Amyloid; Amyloid beta-Peptides; Catechin; Computer Simulation; Drug Antagonism; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Naphthoquinones; Peptide Fragments; Protein Conformation; Thermodynamics; Tryptophan | 2014 |
Application of nanotechnology in improving bioavailability and bioactivity of diet-derived phytochemicals.
Topics: Biological Availability; Catechin; Curcumin; Emulsions; Lactic Acid; Liposomes; Micelles; Nanoparticles; Nanotechnology; Phytochemicals; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Quercetin; Resveratrol; Solubility; Stilbenes | 2014 |
New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate.
Topics: Animals; Antioxidants; Autophagy; Calcium Signaling; Catechin; Cell Membrane; Cyclic AMP; Cyclic GMP; DNA Methylation; Gene Expression Regulation; Humans; Hydrogen Peroxide; Mitochondria; Oxidants; Oxidation-Reduction; Polyphenols; Signal Transduction; Tea; Transcription Factors; Transcription, Genetic | 2014 |
Topoisomerase II and leukemia.
Topics: Animals; Antineoplastic Agents; Catechin; Cell Transformation, Neoplastic; Chromosome Breakage; Curcumin; DNA Topoisomerases, Type II; Genistein; Humans; Infant; Leukemia; Neoplasms, Second Primary; Translocation, Genetic | 2014 |
Tea consumption and leukemia risk: a meta-analysis.
Topics: Catechin; Humans; Leukemia; Publication Bias; Risk; Tea | 2014 |
Prenatal treatment of Down syndrome: a reality?
Topics: Animals; Animals, Newborn; Apigenin; Catechin; Choline; Disease Models, Animal; Down Syndrome; Dyrk Kinases; Female; Fluoxetine; Humans; Mice; Mice, Transgenic; Molecular Targeted Therapy; Neural Stem Cells; Neurogenesis; Neuroprotective Agents; Oxidative Stress; Pregnancy; Prenatal Care; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Stem Cell Transplantation | 2014 |
Protective effects of phytochemical antioxidants against neurotoxin-induced degeneration of dopaminergic neurons.
Topics: Animals; Antioxidants; Catechin; Cyclooxygenase 2; Dopamine; Dopaminergic Neurons; Flavonoids; Humans; Methamphetamine; Microglia; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Phytochemicals; Polyphenols; Reactive Oxygen Species | 2014 |
Pleiotropic beneficial effects of epigallocatechin gallate, quercetin and delphinidin on cardiovascular diseases associated with endothelial dysfunction.
Topics: Anthocyanins; Antioxidants; Apoptosis; Cardiovascular Diseases; Catechin; Endothelium, Vascular; Humans; Quercetin; Reactive Oxygen Species | 2013 |
Nutrition: the future of melanoma prevention?
Topics: Antioxidants; Carotenoids; Catechin; Diet; Grape Seed Extract; Humans; Lycopene; Melanoma; Nutrition Policy; Proanthocyanidins; Resveratrol; Selenium; Skin Neoplasms; Stilbenes; Vitamin D; Vitamin E | 2014 |
Novel mechanisms of anticancer activities of green tea component epigallocatechin- 3-gallate.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Catechin; Cyclic Nucleotide Phosphodiesterases, Type 5; Humans; Neoplasms; Phosphodiesterase 5 Inhibitors; Plant Extracts; Tea | 2014 |
Targeting cancer with nano-bullets: curcumin, EGCG, resveratrol and quercetin on flying carpets.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Antioxidants; Apoptosis; Catechin; Cell Proliferation; Cell Transformation, Neoplastic; Curcumin; Drug Carriers; Humans; Lactic Acid; Mice; Nanoparticles; Neoplasms; Phytochemicals; Polyglycolic Acid; Polyhydroxyethyl Methacrylate; Polylactic Acid-Polyglycolic Acid Copolymer; Quercetin; Resveratrol; Silicon Dioxide; Stilbenes; Xenograft Model Antitumor Assays | 2014 |
Acute effects of tea constituents L-theanine, caffeine, and epigallocatechin gallate on cognitive function and mood: a systematic review and meta-analysis.
Topics: Affect; Attention; Caffeine; Camellia sinensis; Catechin; Cognition; Glutamates; Humans; Plant Extracts; Tea | 2014 |
Plant-derived anti-inflammatory compounds: hopes and disappointments regarding the translation of preclinical knowledge into clinical progress.
Topics: Animals; Anti-Inflammatory Agents; Capsaicin; Catechin; Colchicine; Curcumin; Humans; Imidazoles; Inflammation; Niacin; Resveratrol; Stilbenes | 2014 |
Alternatives to fluoride in the prevention and treatment of dental erosion.
Topics: Catechin; Chlorhexidine; Fluorides; Humans; Matrix Metalloproteinase Inhibitors; Minerals; Protective Agents; Tooth Erosion | 2014 |
The anti-obesity effects of green tea in human intervention and basic molecular studies.
Topics: Adolescent; Adult; Aged; Anti-Obesity Agents; Antioxidants; Camellia sinensis; Catechin; Child; Humans; Lipid Metabolism; Middle Aged; Obesity; Phytotherapy; Polyphenols; Tea; Weight Loss; Young Adult | 2014 |
Having a promising efficacy on type II diabetes, it's definitely a green tea time.
Topics: Animals; Antioxidants; Catechin; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Insulin; Polyphenols; Polysaccharides; Signal Transduction; Tea | 2015 |
The interactions of anticancer agents with tea catechins: current evidence from preclinical studies.
Topics: Animals; Antineoplastic Agents; Catechin; Drug Synergism; Food-Drug Interactions; Humans; Neoplasms; Tea | 2014 |
Regulation of microRNAs by natural agents: new strategies in cancer therapies.
Topics: Antineoplastic Agents; Biological Products; Biomarkers, Tumor; Catechin; Curcumin; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Neoplasms; Resveratrol; RNA Stability; Stilbenes | 2014 |
Vascular and metabolic actions of the green tea polyphenol epigallocatechin gallate.
Topics: Adipose Tissue; Animals; Cardiovascular Diseases; Catechin; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Liver; Muscle, Skeletal; Nitric Oxide; Tea | 2015 |
Dietary polyphenols regulate endothelial function and prevent cardiovascular disease.
Topics: Administration, Oral; Animals; Apigenin; Aryldialkylphosphatase; Cardiovascular Diseases; Catechin; Diet; Disease Models, Animal; Endothelial Cells; Endothelin-1; Humans; Lipoproteins, HDL; Nitric Oxide; Nitric Oxide Synthase Type III; Polyphenols; Signal Transduction; U937 Cells | 2015 |
Synergistic enhancement of anticancer effects on numerous human cancer cell lines treated with the combination of EGCG, other green tea catechins, and anticancer compounds.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Catechin; Cell Line, Tumor; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Tea; Xenograft Model Antitumor Assays | 2015 |
The effect of bioactive compounds in tea on lipid metabolism and obesity through regulation of peroxisome proliferator-activated receptors.
Topics: Acyclic Monoterpenes; Animals; Catechin; Humans; Lipid Metabolism; Monoterpenes; Obesity; Peroxisome Proliferator-Activated Receptors; Tea | 2015 |
Small molecule-sensing strategy and techniques for understanding the functionality of green tea.
Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Camellia sinensis; Catechin; Humans; Receptors, Laminin; Ribosomal Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tea; Tissue Distribution | 2015 |
Epigallocatechin-3-Gallate, a Promising Molecule for Parkinson's Disease?
Topics: Catechin; Humans; Parkinson Disease; Prognosis | 2015 |
Dietary agents for prevention and treatment of lung cancer.
Topics: Adenocarcinoma; Administration, Oral; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Catechin; Curcumin; Flavonoids; Flavonols; Humans; Indoles; Isothiocyanates; Lung Neoplasms; Plant Extracts; Polyphenols | 2015 |
A Review: Phytochemicals Targeting JAK/STAT Signaling and IDO Expression in Cancer.
Topics: Animals; Catechin; Cell Proliferation; Cucurbitacins; Curcumin; Disease Models, Animal; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Janus Kinases; Neoplasms; Phytochemicals; Resveratrol; Signal Transduction; STAT Transcription Factors; Stilbenes | 2015 |
Implications of Green Tea and Its Constituents in the Prevention of Cancer via the Modulation of Cell Signalling Pathway.
Topics: Apoptosis; Catechin; China; Humans; Japan; Neoplasms; Saudi Arabia; Signal Transduction; Tea | 2015 |
The role of targeting kinase activity by natural products in cancer chemoprevention and chemotherapy (Review).
Topics: Antineoplastic Agents, Phytogenic; Catechin; Cell Cycle; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Protein Kinase Inhibitors; Sesquiterpenes; Terpenes | 2015 |
Green Tea and Bone Marrow Transplantation: From Antioxidant Activity to Enzymatic and Multidrug-resistance Modulation.
Topics: Antioxidants; Bone Marrow Transplantation; Catechin; Food-Drug Interactions; Humans; Tea; Uric Acid | 2016 |
Tea Polyphenols in Parkinson's Disease.
Topics: alpha-Synuclein; Antioxidants; Biflavonoids; Catechin; Humans; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Polyphenols; Tea | 2015 |
Green tea polyphenols and their potential role in health and disease.
Topics: Animals; Antioxidants; Catechin; Humans; Oxidation-Reduction; Oxidative Stress; Polyphenols; Tea | 2015 |
Molecular Mechanisms and Therapeutic Effects of (-)-Epicatechin and Other Polyphenols in Cancer, Inflammation, Diabetes, and Neurodegeneration.
Topics: Catechin; Humans; Inflammation; Mitochondria; Neoplasms; Neurodegenerative Diseases; Polyphenols; Reactive Oxygen Species; Signal Transduction | 2015 |
Epigallocatechin Gallate: A Review of Its Beneficial Properties to Prevent Metabolic Syndrome.
Topics: Biological Availability; Catechin; Humans; Metabolic Syndrome; Tea | 2015 |
Over-the-counter anti-oxidant therapies for use in multiple sclerosis: A systematic review.
Topics: Animals; Antioxidants; Catechin; Ginkgo biloba; Humans; Multiple Sclerosis; Nonprescription Drugs; Quercetin; Resveratrol; Stilbenes; Thioctic Acid | 2015 |
Potential Role of (-)-Epigallocatechin-3-Gallate (EGCG) in the Secondary Prevention of Alzheimer Disease.
Topics: Alzheimer Disease; Animals; Catechin; Clinical Trials as Topic; Disease Models, Animal; Humans; Neuroprotective Agents; Oxidative Stress; Secondary Prevention; Treatment Outcome | 2017 |
Compounds Derived from Epigallocatechin-3-Gallate (EGCG) as a Novel Approach to the Prevention of Viral Infections.
Topics: Alcohols; Animals; Camellia sinensis; Catechin; Disinfection; Hand Disinfection; Humans; Virus Diseases | 2015 |
Melatonin as an Antioxidant for Stroke Neuroprotection.
Topics: Animals; Antioxidants; Catechin; Cell- and Tissue-Based Therapy; Humans; Melatonin; Neuroprotection; Neuroprotective Agents; Pineal Gland; Receptors, Melatonin; Stem Cell Transplantation; Stem Cells; Stroke | 2016 |
Enhancing Activity of Anticancer Drugs in Multidrug Resistant Tumors by Modulating P-Glycoprotein through Dietary Nutraceuticals.
Topics: Abietanes; Alkaloids; Allyl Compounds; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Benzodioxoles; beta Carotene; Biflavonoids; Capsaicin; Catechin; Catechols; Curcumin; Dietary Supplements; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Fatty Alcohols; Furocoumarins; Humans; Indoles; Limonins; Neoplasms; Phytotherapy; Piperidines; Polyunsaturated Alkamides; Proanthocyanidins; Quercetin; Resveratrol; Stilbenes; Sulfides; Tea; Triterpenes; Xanthophylls | 2015 |
Analytical techniques for the study of polyphenol-protein interactions.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Binding Sites; Biochemistry; Catechin; Flavonoids; Humans; Ligands; Models, Molecular; Molecular Conformation; Polyphenols; Protein Interaction Domains and Motifs | 2017 |
Mechanisms of body weight reduction and metabolic syndrome alleviation by tea.
Topics: Adipose Tissue; AMP-Activated Protein Kinases; Animals; Camellia sinensis; Cardiovascular Diseases; Catechin; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Liver; Meta-Analysis as Topic; Metabolic Syndrome; Muscle, Skeletal; Plant Leaves; Polyphenols; Randomized Controlled Trials as Topic; Risk Factors; Tea; Weight Loss | 2016 |
Inhibition of IAPP Aggregation and Toxicity by Natural Products and Derivatives.
Topics: Catechin; Curcumin; Diabetes Mellitus, Type 2; Humans; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Resveratrol; Stilbenes | 2016 |
Epigallocatechin gallate and mitochondria-A story of life and death.
Topics: Animals; Biological Availability; Catechin; Cell Death; Humans; Mitochondria | 2016 |
Natural Polyphenols and their Synthetic Analogs as Emerging Anticancer Agents.
Topics: Animals; Anticarcinogenic Agents; Catechin; Clinical Trials as Topic; Humans; Neoplasms; Polyphenols; Signal Transduction; Structure-Activity Relationship; Tea | 2017 |
Prevention and treatment of cancers by immune modulating nutrients.
Topics: Animals; Arginine; Catechin; Cell Line, Tumor; Diet; Disease Models, Animal; Fatty Acids, Unsaturated; Glutamine; Humans; Isothiocyanates; Lignans; Meta-Analysis as Topic; Micronutrients; Neoplasms; Observational Studies as Topic; Phytochemicals; Polyphenols; Randomized Controlled Trials as Topic; Stilbenes | 2016 |
Emerging importance of dietary phytochemicals in fight against cancer: Role in targeting cancer stem cells.
Topics: Catechin; Humans; Neoplasms; Neoplastic Stem Cells; Phytochemicals | 2017 |
Protective role of epigallocatechin-3-gallate in health and disease: A perspective.
Topics: Animals; Catechin; Disease; Health; Humans; Models, Biological; Protective Agents | 2016 |
Oral Cancer Chernoprevention: Current Status and Future Direction.
Topics: Anticarcinogenic Agents; Carcinogenesis; Carotenoids; Catechin; Chemoprevention; Humans; Mouth Neoplasms; Plant Preparations; Precancerous Conditions; Trypsin Inhibitor, Bowman-Birk Soybean; Trypsin Inhibitors | 2016 |
Impact of nanotechnology on the delivery of natural products for cancer prevention and therapy.
Topics: Animals; Anticarcinogenic Agents; Biological Products; Catechin; Cell Line, Tumor; Chemoprevention; Curcumin; Disease Models, Animal; Humans; Nanoparticles; Nanotechnology; Neoplasms; Resveratrol; Stilbenes | 2016 |
Targeting cancer stem-like cells using dietary-derived agents - Where are we now?
Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Curcumin; Diet; Disease Models, Animal; Flavonoids; Humans; Isothiocyanates; Neoplasms; Neoplastic Stem Cells; Randomized Controlled Trials as Topic; Resveratrol; Stilbenes; Sulfoxides; Vitamin A | 2016 |
An Update on Phytochemicals in Molecular Target Therapy of Cancer: Potential Inhibitory Effect on Telomerase Activity.
Topics: Anticarcinogenic Agents; Catechin; Curcumin; Drug Compounding; Humans; Neoplasms; Phytochemicals; Polyphenols; Telomerase | 2016 |
Nutraceuticals in Parkinson's Disease.
Topics: Catechin; Dietary Supplements; Humans; Neuroprotective Agents; Parkinson Disease | 2016 |
Epigallocatechin Gallate Nanodelivery Systems for Cancer Therapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Catechin; Drug Carriers; Drug Compounding; Drug Delivery Systems; Humans; Nanomedicine; Nanoparticles; Neoplasms | 2016 |
Nutritional Epigenetics and the Prevention of Hepatocellular Carcinoma with Bioactive Food Constituents.
Topics: Animals; Butyric Acid; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Curcumin; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Food; Humans; Isothiocyanates; Phytochemicals; Resveratrol; Stilbenes; Sulfoxides | 2016 |
Potential neuroprotective properties of epigallocatechin-3-gallate (EGCG).
Topics: Alzheimer Disease; Animals; Antioxidants; Catechin; Humans; Lipid Peroxidation; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Polyphenols; Reproducibility of Results; Signal Transduction; Tea | 2016 |
Biophysical characteristics of proteins and living cells exposed to the green tea polyphenol epigallocatechin-3-gallate (EGCg): review of recent advances from molecular mechanisms to nanomedicine and clinical trials.
Topics: Animals; Biophysical Phenomena; Catechin; Cells; Clinical Trials as Topic; Humans; Nanomedicine; Proteins; Tea | 2017 |
Systematic review of green tea epigallocatechin gallate in reducing low-density lipoprotein cholesterol levels of humans.
Topics: Body Mass Index; Catechin; Cholesterol, LDL; Humans; Obesity; Plant Extracts; Randomized Controlled Trials as Topic; Tea | 2016 |
Therapeutic effects of EGCG: a patent review.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Catechin; Drug Delivery Systems; Drug Design; Humans; Neuroprotective Agents; Patents as Topic; Tea | 2016 |
Therapeutic potential of green tea on risk factors for type 2 diabetes in obese adults - a review.
Topics: Animals; Antioxidants; Body Composition; Catechin; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Inflammation; Insulin Resistance; Meta-Analysis as Topic; Obesity; Oxidative Stress; Phytotherapy; Randomized Controlled Trials as Topic; Risk Factors; Tea | 2016 |
Topics: Animals; Catechin; Ceramics; Color; Crowns; Cytokines; Dental Porcelain; Dental Veneers; Encephalomyelitis, Autoimmune, Experimental; Humans; Lymphocyte Activation; Materials Testing; T-Lymphocytes; Tea; Time Factors; Zirconium | 2016 |
Where Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability Disorders.
Topics: Antioxidants; Catechin; Cognition; DNA Methylation; Down Syndrome; Epigenesis, Genetic; Fragile X Syndrome; Gene-Environment Interaction; Genetic Therapy; Humans; Intellectual Disability; Protein Interaction Domains and Motifs | 2016 |
Role of angiogenic factors of herbal origin in regulation of molecular pathways that control tumor angiogenesis.
Topics: Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Artemisinins; Catechin; Cell Proliferation; Curcumin; Humans; Neoplasms; Neovascularization, Pathologic; Plant Extracts; Resveratrol; Stilbenes; Triterpenes | 2016 |
Anticancer Efficacy of Polyphenols and Their Combinations.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Biological Availability; Catechin; Cell Line, Tumor; Cell Proliferation; Curcumin; Disease Models, Animal; Humans; Micronutrients; Neoplasms; Plant Extracts; Polyphenols; Quercetin; Resveratrol; Stilbenes; Tea | 2016 |
Anti-inflammatory Action of Green Tea.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Camellia sinensis; Cardiovascular Diseases; Catechin; Diabetes Mellitus; Humans; Inflammation Mediators; Neoplasms; Neurodegenerative Diseases; Obesity; Reactive Oxygen Species; Tea | 2016 |
Absorption, metabolism, anti-cancer effect and molecular targets of epigallocatechin gallate (EGCG): An updated review.
Topics: Animals; Antineoplastic Agents; Catechin; Cell Line, Tumor; Drug Synergism; Humans; Neoplasms; Neoplastic Stem Cells; Polyphenols; Tea | 2018 |
Synergistic Anticancer Effect of Tocotrienol Combined with Chemotherapeutic Agents or Dietary Components: A Review.
Topics: Antineoplastic Agents; Catechin; Coumaric Acids; Dietary Supplements; Dioxoles; Drug Synergism; Drug Therapy, Combination; Humans; Lignans; Neoplasms; Resveratrol; Stilbenes; Tocotrienols | 2016 |
Stability of (-)-epigallocatechin gallate and its activity in liquid formulations and delivery systems.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antioxidants; Catechin; Dietary Supplements; Drug Delivery Systems; Drug Stability; Food Preservation; Food Preservatives; Humans; Liposomes; Nanoparticles; Oxidation-Reduction; Preservatives, Pharmaceutical; Solubility; Stereoisomerism | 2016 |
Plant polyphenols as natural drugs for the management of Down syndrome and related disorders.
Topics: Biological Products; Catechin; Down Syndrome; Humans; Mitochondria; Polyphenols | 2016 |
Biophysical Approach to Mechanisms of Cancer Prevention and Treatment with Green Tea Catechins.
Topics: Animals; Biochemical Phenomena; Catechin; Cell Movement; Humans; Microfluidics; Microscopy, Atomic Force; Neoplasms; Optical Phenomena; Plant Extracts; Tea | 2016 |
Emerging Phytochemicals for the Prevention and Treatment of Head and Neck Cancer.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biphenyl Compounds; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Evaluation, Preclinical; Head and Neck Neoplasms; Humans; Lignans; Magnolia; Polyphenols; Proanthocyanidins; Squamous Cell Carcinoma of Head and Neck; Tea; Vitis | 2016 |
Synthesis of Effective Food Constituents toward the Development of Chemical Biology Investigations.
Topics: Catechin; Cyclization; Flavones; Flavonoids; Fluorescent Dyes; Food; Polyphenols; Positron Emission Tomography Computed Tomography; Tea; Vaccines, Synthetic | 2016 |
Cancer Preventive Activities of Tea Catechins.
Topics: Animals; Apoptosis; Catechin; Cell Proliferation; Cell Transformation, Neoplastic; Humans; Neoplasms; Neovascularization, Pathologic; Tea | 2016 |
Cancer therapeutics with epigallocatechin-3-gallate encapsulated in biopolymeric nanoparticles.
Topics: Animals; Anticarcinogenic Agents; Biopolymers; Catechin; Humans; Nanoparticles; Neoplasms | 2017 |
Bioactive nutrients - Time for tolerable upper intake levels to address safety.
Topics: Animals; Catechin; Consumer Product Safety; Decision Support Techniques; Dietary Supplements; Dose-Response Relationship, Drug; Food Safety; Guidelines as Topic; Humans; Lutein; No-Observed-Adverse-Effect Level; Plant Preparations; Recommended Dietary Allowances; Risk Assessment; Toxicity Tests; Toxicology | 2017 |
Targeting Cancer Stem Cells for Chemoprevention of Pancreatic Cancer.
Topics: Catechin; Doublecortin-Like Kinases; Hedgehog Proteins; Humans; Intracellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinases; Neoplastic Stem Cells; Pancreatic Neoplasms; Phytochemicals; Protein Serine-Threonine Kinases; Signal Transduction; Wnt Proteins | 2018 |
Targeting miRNAs by polyphenols: Novel therapeutic strategy for cancer.
Topics: Catechin; Curcumin; Gene Expression Regulation, Neoplastic; Genistein; Humans; MicroRNAs; Neoplasms; Polyphenols; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Green tea and its anti-angiogenesis effects.
Topics: Animals; Catechin; Humans; MicroRNAs; Neovascularization, Pathologic; Tea; Vascular Endothelial Growth Factors | 2017 |
Challenges and complexity of functionality evaluation of flavan-3-ol derivatives.
Topics: Catechin; Flavonoids; Functional Food; Health Promotion; Humans; Molecular Structure; Polyphenols; Proanthocyanidins; Structure-Activity Relationship; Tea | 2017 |
Natural Polyphenols in the Treatment of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Catechin; Curcumin; Disease Progression; Humans; Neuroprotective Agents; Oxidative Stress; Polyphenols; Resveratrol | 2018 |
Galloylation of polyphenols alters their biological activity.
Topics: Animals; Catechin; Humans; Polyphenols; Structure-Activity Relationship | 2017 |
Polyphenol nanoformulations for cancer therapy: experimental evidence and clinical perspective.
Topics: Antineoplastic Agents; Antioxidants; Biological Availability; Catechin; Curcumin; Drug Delivery Systems; Humans; Nanocomposites; Nanoparticles; Neoplasms; Polyphenols; Quercetin; Resveratrol; Stilbenes | 2017 |
Prevention of Colorectal Cancer by Targeting Obesity-Related Disorders and Inflammation.
Topics: Animals; Catechin; Colorectal Neoplasms; Humans; Inflammation; Obesity; Phytochemicals; Receptor Protein-Tyrosine Kinases; Tea | 2017 |
Dietary Polyphenols and Mitochondrial Function: Role in Health and Disease.
Topics: Animals; Catechin; Curcumin; Humans; Mitochondria; Mitochondrial Diseases; Oxidative Stress; Quercetin; Resveratrol | 2019 |
Inhibition of hazardous compound formation in muscle foods by antioxidative phytophenols.
Topics: Antioxidants; Catechin; Flavonoids; Free Radical Scavengers; Humans; Plant Extracts; Plant Leaves; Polyphenols; Spices | 2017 |
An overview of pre-clinical studies on the effects of (-)-epigallocatechin-3-gallate, a catechin found in green tea, in treatment of pancreatic cancer
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Availability; Catechin; Disease Progression; Disease-Free Survival; Humans; Pancreatic Neoplasms; Signal Transduction; Tea | 2017 |
Safety assessment of green tea based beverages and dried green tea extracts as nutritional supplements.
Topics: Animals; Camellia sinensis; Catechin; Consumer Product Safety; Dietary Supplements; Food Safety; Hazard Analysis and Critical Control Points; Humans; No-Observed-Adverse-Effect Level; Plant Extracts; Recommended Dietary Allowances; Risk Assessment; Tea; Teas, Herbal | 2017 |
Antioxidant dietary approach in treatment of fatty liver: New insights and updates.
Topics: Animals; Anthocyanins; Antioxidants; Carotenoids; Catechin; Coumestrol; Curcumin; Energy Metabolism; Fatty Liver; Glucosinolates; Humans; Imidoesters; Isothiocyanates; Lipogenesis; Mitochondria; Non-alcoholic Fatty Liver Disease; Nutritional Sciences; Oxidative Stress; Oximes; Polyphenols; Quercetin; Resveratrol; Stilbenes; Sulfoxides; Xanthophylls | 2017 |
Therapeutic Potential of Epigallocatechin Gallate Nanodelivery Systems.
Topics: Animals; Catechin; Disease; Drug Carriers; Drug Delivery Systems; Humans; Nanoparticles | 2017 |
Potential Biological Effects of (-)-Epigallocatechin-3-gallate on the Treatment of Nonalcoholic Fatty Liver Disease.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Autophagy; Body Weight; Catechin; Humans; Lipid Metabolism; Non-alcoholic Fatty Liver Disease; Receptors, LDL | 2018 |
Molecular understanding of Epigallocatechin gallate (EGCG) in cardiovascular and metabolic diseases.
Topics: Animals; Anti-Inflammatory Agents; Camellia sinensis; Cardiovascular Agents; Cardiovascular Diseases; Catechin; Humans; Metabolic Diseases; Tea | 2018 |
In vitro Biological Effects of Sulforaphane (SFN), Epigallocatechin-3-gallate (EGCG), and Curcumin on Breast Cancer Cells: A Systematic Review of the Literature.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Catechin; Cell Cycle; Cell Line, Tumor; Curcumin; Epigenesis, Genetic; Female; Humans; Isothiocyanates; Sulfoxides; Telomerase | 2017 |
Green Tea Extracts Epigallocatechin-3-gallate for Different Treatments.
Topics: Antioxidants; Catechin; Humans; Inflammation; Neoplasms; Polyphenols; Tea | 2017 |
Green tea effects on cognition, mood and human brain function: A systematic review.
Topics: Affect; Brain; Caffeine; Camellia sinensis; Catechin; Cognition; Glutamates; Humans; Plant Extracts; Randomized Controlled Trials as Topic; Tea | 2017 |
Food macromolecule based nanodelivery systems for enhancing the bioavailability of polyphenols.
Topics: Biological Availability; Catechin; Diet; Flavonoids; Humans; Nanostructures; Polyphenols | 2017 |
Human cancer stem cells are a target for cancer prevention using (-)-epigallocatechin gallate.
Topics: Animals; Biomarkers, Tumor; Catechin; Humans; Neoplasms; Neoplastic Stem Cells | 2017 |
Sulforaphane and Epigallocatechin Gallate Restore Estrogen Receptor Expression by Modulating Epigenetic Events in the Breast Cancer Cell Line MDA-MB-231: A Systematic Review and Meta-Analysis.
Topics: Anticarcinogenic Agents; Apoptosis; Breast Neoplasms; Catechin; Cell Line, Tumor; Epigenesis, Genetic; Female; Gene Expression; Humans; Isothiocyanates; Nutrigenomics; Receptors, Estrogen; Sulfoxides | 2017 |
The roles of epigallocatechin-3-gallate in the treatment of neuropathic pain: an update on preclinical in vivo studies and future perspectives.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Camellia sinensis; Catechin; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Neuralgia | 2017 |
Effect of green tea on plasma leptin and ghrelin levels: A systematic review and meta-analysis of randomized controlled clinical trials.
Topics: Catechin; Ghrelin; Humans; Leptin; Obesity; Plant Extracts; Randomized Controlled Trials as Topic; Sensitivity and Specificity; Tea | 2018 |
Gallic Acid and Gallates in Human Health and Disease: Do Mitochondria Hold the Key to Success?
Topics: Antineoplastic Agents; Apoptosis; Biological Availability; Catechin; Cell Respiration; Cytoprotection; Gallic Acid; Humans; Mitochondria; Neuroprotective Agents; Reactive Oxygen Species | 2018 |
Alternative Oral Agents in Prophylaxis and Therapy of Uterine Fibroids-An Up-to-Date Review.
Topics: Administration, Oral; Antineoplastic Agents; Aromatase Inhibitors; Cabergoline; Catechin; Ergocalciferols; Ergolines; Female; Humans; Hydrocarbons, Fluorinated; Leiomyoma; Pyrimidines; Quality of Life; Uterine Neoplasms; Vitamin D | 2017 |
Can EGCG Alleviate Symptoms of Down Syndrome by Altering Proteolytic Activity?
Topics: Animals; Biomarkers; Catechin; Down Syndrome; Humans; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Methylation; Proteolysis; Signal Transduction; Tissue Plasminogen Activator | 2018 |
Beneficial Effects of Flavonoids Against Parkinson's Disease.
Topics: Animals; Anthocyanins; Antioxidants; Antiparkinson Agents; Catechin; Cell Line; Corpus Striatum; Disease Models, Animal; Dopamine; Flavanones; Flavones; Flavonoids; Flavonols; Humans; Isoflavones; Kaempferols; Neuroprotective Agents; Oxidative Stress; Parkinson Disease | 2018 |
Cancer Prevention with Green Tea and Its Principal Constituent, EGCG: from Early Investigations to Current Focus on Human Cancer Stem Cells.
Topics: Animals; Catechin; Cell Movement; Clinical Trials as Topic; Humans; Mice; Neoplasms; Neoplastic Stem Cells; Phytotherapy; Tea | 2018 |
Food-grade Encapsulation Systems for (-)-Epigallocatechin Gallate.
Topics: Carbohydrates; Catechin; Drug Compounding; Food; Humans; Lipids; Tea | 2018 |
Effects of the Green Tea Polyphenol Epigallocatechin-3-Gallate on Glioma: A Critical Evaluation of the Literature.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Catechin; Cell Proliferation; Central Nervous System Neoplasms; Combined Modality Therapy; Endoplasmic Reticulum Chaperone BiP; Epidemiologic Studies; Glioma; Humans; Neoplasms, Experimental; Signal Transduction; Tea | 2018 |
Role of EGCG in Containing the Progression of Lung Tumorigenesis - A Multistage Targeting Approach.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Camellia sinensis; Catechin; Cell Line, Tumor; Humans; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; Molecular Structure; Signal Transduction | 2018 |
The critical role of epigallocatechin gallate in regulating mitochondrial metabolism.
Topics: Animals; Apoptosis; Catechin; Cell Cycle; Energy Metabolism; Environmental Pollutants; Humans; Mitochondria; Organelle Biogenesis; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Tea | 2018 |
Perspectives on the recent developments with green tea polyphenols in drug discovery.
Topics: Animals; Anticarcinogenic Agents; Catechin; Drug Discovery; Humans; Nanoparticles; Neoplasms; Polyphenols; Prodrugs; Tea | 2018 |
Regulatory Roles of Flavonoids on Inflammasome Activation during Inflammatory Responses.
Topics: Animals; Apigenin; Biflavonoids; Catechin; Chalcones; Drug Development; Flavonoids; Humans; Inflammasomes; Inflammation; Luteolin; Proanthocyanidins; Quercetin; Rutin | 2018 |
In Vitro and In Silico Studies of the Molecular Interactions of Epigallocatechin-3-
Topics: Catechin; Computer Simulation; Crystallography, X-Ray; Drug Design; Humans; In Vitro Techniques; Models, Molecular; Molecular Docking Simulation; Proteins; Surface Plasmon Resonance; Tea | 2018 |
Beneficial Effects of Green Tea Catechins on Neurodegenerative Diseases.
Topics: alpha-Synuclein; Alzheimer Disease; Amyloid beta-Peptides; Camellia sinensis; Catechin; Cerebral Cortex; Humans; Molecular Docking Simulation; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Tea | 2018 |
Regulation of Immune Function by Polyphenols.
Topics: Animals; Catechin; Curcumin; Epigenesis, Genetic; Humans; Hypersensitivity; Immunity; Immunomodulation; Inflammation; Neoplasms; Nutritional Physiological Phenomena; Oxidative Stress; Polyphenols; Signal Transduction | 2018 |
Efficacy of tea catechin-rich beverages to reduce abdominal adiposity and metabolic syndrome risks in obese and overweight subjects: a pooled analysis of 6 human trials.
Topics: Abdominal Fat; Adult; Camellia sinensis; Catechin; Female; Humans; Intra-Abdominal Fat; Male; Metabolic Syndrome; Middle Aged; Obesity; Overweight; Phytotherapy; Plant Extracts; Subcutaneous Fat; Tea; Treatment Outcome | 2018 |
Nutritional prevention of cognitive decline and dementia.
Topics: Antioxidants; Autophagy; Caffeine; Catechin; Central Nervous System Stimulants; Chocolate; Cognitive Dysfunction; Curcumin; Dementia; Diet; Fatty Acids, Omega-3; Garlic; Ginkgo biloba; Healthy Aging; Humans; Inflammation; Magnesium; Oxidative Stress; Phytoestrogens; Phytotherapy; Resveratrol; Tea; Vitamins | 2018 |
The green tea polyphenolic catechin epigallocatechin gallate and neuroprotection.
Topics: Animals; Apoptosis; Brain; Brain Injuries; Catechin; Clinical Trials as Topic; Humans; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Plant Extracts; Spinal Cord Injuries; Tea | 2020 |
Suppressive Effects of EGCG on Cervical Cancer.
Topics: Anticarcinogenic Agents; Bleomycin; Catechin; Cell Proliferation; Cell Survival; Cisplatin; Drug Synergism; Female; Humans; Uterine Cervical Neoplasms | 2018 |
(-)-Epigallocatechin-3-gallate induces cell apoptosis in chronic myeloid leukaemia by regulating Bcr/Abl-mediated p38-MAPK/JNK and JAK2/STAT3/AKT signalling pathways.
Topics: Animals; Apoptosis; Catechin; Humans; Janus Kinase 2; JNK Mitogen-Activated Protein Kinases; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-abl; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcr; Signal Transduction; STAT3 Transcription Factor | 2019 |
Antiviral Mechanism of Action of Epigallocatechin-3-
Topics: Animals; Antiviral Agents; Catechin; Fatty Acids; Humans; Virus Diseases; Virus Physiological Phenomena | 2018 |
Studies on the Prevention of Cancer and Cardiometabolic Diseases by Tea: Issues on Mechanisms, Effective Doses, and Toxicities.
Topics: Animals; Camellia sinensis; Cardiovascular Diseases; Catechin; Humans; Neoplasms; Randomized Controlled Trials as Topic; Tea | 2019 |
Pathophysiological mechanisms of diabetic cardiomyopathy and the therapeutic potential of epigallocatechin-3-gallate.
Topics: Animals; Antioxidants; Catechin; Diabetic Cardiomyopathies; Humans; Oxidative Stress; Polyphenols; Tea | 2019 |
Molecular Targets of Epigallocatechin-Gallate (EGCG): A Special Focus on Signal Transduction and Cancer.
Topics: Camellia sinensis; Catechin; DNA Methylation; Humans; Metalloproteases; Methyltransferases; Neoplasms; NIMA-Interacting Peptidylprolyl Isomerase; Phytotherapy; Plant Extracts; Polyphenols; Receptors, Cell Surface; Signal Transduction; Tea | 2018 |
Green tea can supress rabbit ovarian functions in vitro and in vivo.
Topics: Animals; Apoptosis; Caspase 3; Catechin; Female; Fertility; Ovary; Polyphenols; Rabbits; Resveratrol; Tea | 2019 |
Epigallocatechin Gallate Modulates Muscle Homeostasis in Type 2 Diabetes and Obesity by Targeting Energetic and Redox Pathways: A Narrative Review.
Topics: Animals; Catechin; Diabetes Mellitus, Type 2; Disease Models, Animal; Energy Metabolism; Epigenesis, Genetic; Glucose; Homeostasis; Humans; Lipid Metabolism; Muscle, Skeletal; NF-kappa B; Obesity; Oxidative Stress; Signal Transduction | 2019 |
The immunomodulatory potential of natural compounds in tumor-bearing mice and humans.
Topics: Animals; beta-Glucans; Carotenoids; Catechin; Curcumin; Humans; Immune System; Immunologic Factors; Killer Cells, Natural; Mice; Neoplasms; Resveratrol; T-Lymphocytes; Tretinoin; Tumor Microenvironment | 2019 |
Nanochemoprevention with therapeutic benefits: An updated review focused on epigallocatechin gallate delivery.
Topics: Catechin; Humans; Nanoparticles; Tea | 2020 |
ADAM10 in Alzheimer's disease: Pharmacological modulation by natural compounds and its role as a peripheral marker.
Topics: ADAM10 Protein; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Biomarkers; Catechin; Ginkgo biloba; Humans; Membrane Proteins; Neuroprotective Agents; Plant Extracts | 2019 |
Inhibitory Effects of (-)-Epigallocatechin-3-gallate on Esophageal Cancer.
Topics: Antineoplastic Agents; Catechin; Cell Proliferation; DNA Methylation; Esophageal Neoplasms; Humans; Polyphenols; Signal Transduction; Tea | 2019 |
Epigallocatechin-3-gallate in the prevention and treatment of hepatocellular carcinoma: experimental findings and translational perspectives.
Topics: Animals; Carcinoma, Hepatocellular; Catechin; Humans; Liver Neoplasms | 2019 |
Advances in the Antagonism of Epigallocatechin-3-gallate in the Treatment of Digestive Tract Tumors.
Topics: Administration, Oral; Biological Availability; Catechin; Cell Cycle; Cell Line, Tumor; Cell Survival; Drug Discovery; Gastrointestinal Neoplasms; Humans; Tea | 2019 |
Quercetin and Epigallocatechin Gallate in the Prevention and Treatment of Obesity: From Molecular to Clinical Studies.
Topics: Adipose Tissue; Animals; Catechin; Humans; Obesity; Quercetin | 2019 |
Prenatal epigenetics diets play protective roles against environmental pollution.
Topics: Ascorbic Acid; Brassica; Catechin; Diet; Environmental Pollutants; Epigenesis, Genetic; Female; Genistein; Humans; Plant Extracts; Pregnancy; Protective Agents; Resveratrol | 2019 |
Targeting Bacterial Biofilms by the Green Tea Polyphenol EGCG.
Topics: Amyloid; Anti-Bacterial Agents; Bacteria; Biofilms; Catechin; Drug Synergism; Ethanolamines; Tea | 2019 |
Fabrication, structure, and function evaluation of the ferritin based nano-carrier for food bioactive compounds.
Topics: Anthocyanins; beta Carotene; Biological Availability; Catechin; Chitosan; Curcumin; Ferritins; Food; Humans; Nanostructures; Polyphenols; Proanthocyanidins; Solubility | 2019 |
Pharmaceutical Topical Delivery of Poorly Soluble Polyphenols: Potential Role in Prevention and Treatment of Melanoma.
Topics: Animals; Antioxidants; Biological Availability; Catechin; Curcumin; Drug Delivery Systems; Humans; Melanoma; Nanoparticles; Polyphenols; Quercetin; Resveratrol; Skin Neoplasms; Solubility | 2019 |
Polyphenols Regulate Endothelial Functions and Reduce the Risk of Cardiovascular Disease.
Topics: Antioxidants; Cardiovascular Diseases; Catechin; Diet; Endothelium, Vascular; Flavonoids; Humans; Polyphenols; Quercetin; Resveratrol | 2019 |
Function of Green Tea Catechins in the Brain: Epigallocatechin Gallate and its Metabolites.
Topics: Animals; Blood-Brain Barrier; Brain; Catechin; Cognition; Humans; Molecular Structure; Neurogenesis; Permeability; Plant Extracts; Structure-Activity Relationship; Tea | 2019 |
Antioxidants as Adjuvants in Periodontitis Treatment: A Systematic Review and Meta-Analysis.
Topics: Antioxidants; Catechin; Chronic Periodontitis; Databases, Factual; Hemorrhage; Humans; Periodontal Index; Reactive Oxygen Species | 2019 |
Phytochemicals based chemopreventive and chemotherapeutic strategies and modern technologies to overcome limitations for better clinical applications.
Topics: Catechin; Chemoprevention; Curcumin; Humans; Phytochemicals; Resveratrol | 2019 |
Targeting miRNAs by polyphenols: Novel therapeutic strategy for aging.
Topics: Aging; Cardiovascular Diseases; Catechin; Gene Expression Regulation; Humans; Longevity; MicroRNAs; Neoplasms; Nervous System Diseases; Polyphenols | 2020 |
Nanophytomedicine Based Novel Therapeutic Strategies in Liver Cancer.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Catechin; Curcumin; Drug Compounding; Drug Stability; Humans; Liver Neoplasms; Nanocapsules; Plant Extracts; Quercetin; Resveratrol; Solubility; Theranostic Nanomedicine | 2020 |
New therapeutic approaches for endometriosis besides hormonal therapy.
Topics: Animals; Catechin; Endometriosis; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Resveratrol; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2019 |
Quercetin, Epigallocatechin Gallate, Curcumin, and Resveratrol: From Dietary Sources to Human MicroRNA Modulation.
Topics: Antioxidants; Catechin; Curcumin; Dietary Supplements; Gene Expression Regulation; Humans; MicroRNAs; Oxidative Stress; Polyphenols; Quercetin; Resveratrol | 2019 |
Protective Effect of Epigallocatechin Gallate on Endothelial Disorders in Atherosclerosis.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Atherosclerosis; Catechin; Cell Adhesion Molecules; Endothelial Cells; Endothelin-1; Endothelium, Vascular; Humans; Nitric Oxide; Oxidative Stress | 2020 |
From tea to treatment; epigallocatechin gallate and its potential involvement in minimizing the metabolic changes in cancer.
Topics: Camellia sinensis; Catechin; Humans; Male; Phosphoinositide-3 Kinase Inhibitors; Plant Leaves; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction; Tea; TOR Serine-Threonine Kinases | 2020 |
Preclinical Pharmacological Activities of Epigallocatechin-3-gallate in Signaling Pathways: An Update on Cancer.
Topics: Animals; Catechin; Cell Line, Tumor; ErbB Receptors; Humans; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Signal Transduction; Tea | 2020 |
Plasticity as a therapeutic target for improving cognition and behavior in Down syndrome.
Topics: Animals; Antioxidants; Brain; Catechin; Down Syndrome; Humans; Neuronal Plasticity; Social Environment | 2020 |
Natural polyphenols in preclinical models of epilepsy.
Topics: Animals; Catechin; Disease Models, Animal; Epilepsy; Humans; Male; Polyphenols; Quercetin; Rats; Rats, Sprague-Dawley; Resveratrol | 2020 |
Anti-Amyloid Aggregating Gold Nanoparticles: Can they Really be Translated from Bench to Bedside for Alzheimer's Disease Treatment?
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Biomarkers; Blood-Brain Barrier; Brain; Catechin; Gene Expression Regulation; Gold; Humans; Metal Nanoparticles; Molecular Targeted Therapy; Neuroprotective Agents; Protein Aggregates; Resveratrol; Translational Research, Biomedical | 2020 |
The "Big Five" Phytochemicals Targeting Cancer Stem Cells: Curcumin, EGCG, Sulforaphane, Resveratrol and Genistein.
Topics: Animals; Catechin; Curcumin; Genistein; Hedgehog Proteins; Humans; Isothiocyanates; Mice; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Phosphatidylinositol 3-Kinases; Phytochemicals; Resveratrol; Sulfoxides | 2021 |
Great green tea ingredient? A narrative literature review on epigallocatechin gallate and its biophysical properties for topical use in dermatology.
Topics: Administration, Topical; Antioxidants; Biophysical Phenomena; Catechin; Cosmetics; Dermatology; Humans; Imiquimod; Plant Extracts; Psoriasis; Tea | 2020 |
Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Amylose; Anaerobiosis; Animals; Anti-Bacterial Agents; Anura; Arginase; Arthritis, Rheumatoid; Asthma; Atmosphere; B-Lymphocytes; Basic Helix-Loop-Helix Transcription Factors; Bioelectric Energy Sources; Biofilms; Biofuels; Biomarkers; Biopolymers; Bioreactors; Brain; Brain Injuries, Traumatic; Breast Neoplasms; Calibration; Carbon Tetrachloride; Caspase 3; Catalysis; Catechin; Cations; Cattle; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Body; Cell Line, Tumor; Cell Plasticity; Chemical and Drug Induced Liver Injury; Chemistry Techniques, Synthetic; China; Chitosan; Chloride Channels; Chromatography, High Pressure Liquid; Chromosome Mapping; Cognition; Cognitive Dysfunction; Cohort Studies; Colitis, Ulcerative; Colloids; Coloring Agents; Congresses as Topic; Correlation of Data; Crystallization; Cyanoacrylates; Cyclohexane Monoterpenes; Cyprinidae; Cytochrome P-450 CYP1A1; Death, Sudden; Dent Disease; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Disease Progression; Disease Resistance; Disulfides; Drug Monitoring; Drug Stability; Ecotoxicology; Electricity; Electrodes; Endocytosis; Environmental Exposure; Environmental Monitoring; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Esophageal and Gastric Varices; Esters; Fagopyrum; Female; Ferrosoferric Oxide; Flame Retardants; Flavobacteriaceae; Flow Cytometry; Follow-Up Studies; Formoterol Fumarate; Fusarium; Garlic; Gastrointestinal Hemorrhage; Gene Expression; Genes, Plant; Genetic Markers; Glial Fibrillary Acidic Protein; Gliosis; Global Health; Glutathione Transferase; Glycine max; Gum Arabic; Hemostasis, Endoscopic; Hepatocytes; Hippocampus; Humans; Hydrogen-Ion Concentration; Illinois; Immunoglobulin G; Indoleamine-Pyrrole 2,3,-Dioxygenase; Infant, Newborn; Infant, Small for Gestational Age; Injections, Intraperitoneal; Interleukin-4; Iowa; Iron; Ki-67 Antigen; Kidney; Kinetics; Kynurenine; Lakes; Levofloxacin; Lipid Peroxidation; Lipids; Liver; Liver Cirrhosis, Experimental; Magnetic Fields; Magnetic Iron Oxide Nanoparticles; Male; Manure; Maze Learning; Memory, Short-Term; Metal Nanoparticles; Metals, Heavy; Methane; Mice; Mice, Inbred C57BL; Mice, Knockout; Michigan; Microalgae; Microbial Consortia; Mitochondria; Models, Animal; Models, Chemical; Models, Neurological; Molecular Structure; Molecular Weight; Mutation; Myeloid-Derived Suppressor Cells; NADPH Oxidase 2; Neoplasm Recurrence, Local; Neurites; Neurons; Neuroprotective Agents; NF-kappa B; NIH 3T3 Cells; Nitric Oxide Synthase Type II; Nitrogen; Ohio; Ointments; Ontario; Organelle Biogenesis; Organophosphates; Organophosphorus Compounds; Oxidative Stress; Palladium; Particle Size; Pectins; Phenotype; Phytotherapy; Piperidines; Placenta; Plant Diseases; Plant Extracts; Polymers; Polymorphism, Genetic; Polyphenols; Powders; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Protein Kinase Inhibitors; Protein Structure, Secondary; Proteins; Pyridines; Pyrimidines; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Receptors, Chemokine; Receptors, Formyl Peptide; Receptors, Lipoxin; Recovery of Function; Recurrence; Reference Standards; Reference Values; Reproducibility of Results; Respiratory Function Tests; Retrospective Studies; Risk; Sensitivity and Specificity; Sewage; Signal Transduction; Sodium Glutamate; Soil; Solanum tuberosum; Solubility; Solutions; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spermatozoa; STAT3 Transcription Factor; Sulfamethoxazole; Tea; Temperature; Thermodynamics; Thrombin; Treatment Outcome; Triazoles; United States; Viscosity; Waste Disposal, Fluid; Wastewater; Water; Water Pollutants, Chemical; Water Purification; White Matter; Wisconsin; X-Ray Diffraction; Zea mays | 2013 |
The Epigenetic Modification of Epigallocatechin Gallate (EGCG) on Cancer.
Topics: Anticarcinogenic Agents; Catechin; Cell Line, Tumor; DNA Modification Methylases; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Humans; MicroRNAs; Neoplasms | 2020 |
Application of green tea extracts epigallocatechin-3-gallate in dental materials: Recent progress and perspectives.
Topics: Anti-Bacterial Agents; Antioxidants; Cariostatic Agents; Catechin; Dental Caries; Humans; Periodontal Diseases; Plant Extracts; Tea | 2020 |
Molecular mechanisms of action of epigallocatechin gallate in cancer: Recent trends and advancement.
Topics: Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Humans; Neoplasms; Prospective Studies; Reproducibility of Results | 2022 |
The Role of Histone Acetylation and the Microbiome in Phytochemical Efficacy for Cardiovascular Diseases.
Topics: Acetylation; Animals; Cardiovascular Diseases; Catechin; Curcumin; Epigenesis, Genetic; Histone Deacetylases; Histones; Humans; Microbiota; Phytochemicals; Protein Processing, Post-Translational; Resveratrol | 2020 |
Secondary Metabolites from Plants Possessing Inhibitory Properties against Beta-Amyloid Aggregation as Revealed by Thioflavin-T Assay and Correlations with Investigations on Transgenic Mouse Models of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Biological Products; Catechin; Flavonoids; Fluorescent Dyes; Luteolin; Mice; Mice, Transgenic; Protein Aggregates; Silybin | 2020 |
A review for physiological activities of EGCG and the role in improving fertility in humans/mammals.
Topics: Animals; Antineoplastic Agents; Antioxidants; Antiviral Agents; Catechin; Fertility; Fertility Agents; Humans; Infertility; Mammals | 2020 |
The Intrinsic Virtues of EGCG, an
Topics: Animals; Antioxidants; Cardiovascular Diseases; Catechin; Diabetes Mellitus; Humans; Obesity; Signal Transduction | 2020 |
Potential Therapeutic Targets of Epigallocatechin Gallate (EGCG), the Most Abundant Catechin in Green Tea, and Its Role in the Therapy of Various Types of Cancer.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Catechin; Cell Proliferation; Drug Carriers; Humans; Nanostructures; Neoplasms; Signal Transduction; Tea | 2020 |
Protective Effect of Epigallocatechin-3-Gallate (EGCG) in Diseases with Uncontrolled Immune Activation: Could Such a Scenario Be Helpful to Counteract COVID-19?
Topics: Anti-Inflammatory Agents; Antioxidants; Autoimmune Diseases; Betacoronavirus; Catechin; Coronavirus Infections; COVID-19; Cytokine Release Syndrome; Humans; NF-kappa B; Pandemics; Plant Extracts; Pneumonia, Viral; Pulmonary Fibrosis; SARS-CoV-2; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor | 2020 |
Antiviral activity of green tea and black tea polyphenols in prophylaxis and treatment of COVID-19: A review.
Topics: Antioxidants; Antiviral Agents; Biflavonoids; Binding Sites; Camellia sinensis; Catechin; COVID-19 Drug Treatment; Humans; Polyphenols; SARS-CoV-2; Tea | 2021 |
Prooxidant Effects of Epigallocatechin-3-Gallate in Health Benefits and Potential Adverse Effect.
Topics: Animals; Catechin; Health; Humans; Lipid Metabolism; Models, Biological; Oxidation-Reduction; Reactive Oxygen Species | 2020 |
Regulation of p27
Topics: Antineoplastic Agents, Phytogenic; Catechin; Cell Cycle; Cell Line, Tumor; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinase Inhibitor p57; Cytoplasm; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Proteasome Endopeptidase Complex; Protein Domains; Proteolysis; Resveratrol | 2020 |
The pharmacological activity of epigallocatechin-3-gallate (EGCG) on Alzheimer's disease animal model: A systematic review.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Antioxidants; Blood-Brain Barrier; Catechin; Cognition; Disease Models, Animal; Humans; Neuroprotective Agents; Phosphorylation | 2020 |
The Role of Epigallocatechin-3-Gallate in Autophagy and Endoplasmic Reticulum Stress (ERS)-Induced Apoptosis of Human Diseases.
Topics: Apoptosis; Autophagy; Cardiovascular Diseases; Catechin; Diabetes Mellitus; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Humans; Neoplasms; Nervous System Diseases; Signal Transduction | 2020 |
Anti-Cancer Effects of Green Tea Epigallocatchin-3-Gallate and Coffee Chlorogenic Acid.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Catechin; Chlorogenic Acid; Coffee; Humans; Neoplasms; Tea | 2020 |
Protective Effects of Epigallocatechin Gallate (EGCG) on Endometrial, Breast, and Ovarian Cancers.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Catechin; Endometrial Neoplasms; Epithelial-Mesenchymal Transition; Female; Humans; NF-E2-Related Factor 2; Ovarian Neoplasms; Protective Agents; Tea | 2020 |
The Potential Roles of Epigallocatechin-3-Gallate in the Treatment of Ovarian Cancer: Current State of Knowledge.
Topics: Antineoplastic Agents, Phytogenic; Catechin; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Recurrence, Local; Ovarian Neoplasms | 2020 |
Development of High-Order Functions Using (-)-Epigallocatechin-3-O-gallate in Water.
Topics: Catechin; Deuterium Oxide; Drug Development; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Stereoisomerism | 2020 |
The Role of EGCG in Breast Cancer Prevention and Therapy.
Topics: Animals; Antineoplastic Agents; Antioxidants; Breast Neoplasms; Catechin; Cell Proliferation; Female; Humans; Mammary Neoplasms, Experimental; Vascular Endothelial Growth Factors | 2021 |
Nutraceutical Approaches of Autophagy and Neuroinflammation in Alzheimer's Disease: A Systematic Review.
Topics: Alzheimer Disease; Animals; Autophagy; Catechin; Cellular Senescence; Dietary Supplements; Flavonols; Humans; Inflammation; Spermidine | 2020 |
Natural products: The role and mechanism in low-density lipoprotein oxidation and atherosclerosis.
Topics: Abietanes; Antioxidants; Atherosclerosis; Biological Products; Catechin; Dietary Supplements; Humans; Lipoproteins, LDL; Lycopene; Phytotherapy; Plant Extracts; Probucol; Quercetin; Resveratrol; Vitamin E | 2021 |
Updated review on green tea polyphenol epigallocatechin-3-gallate as a cancer epigenetic regulator.
Topics: Catechin; Epigenesis, Genetic; Humans; Neoplasms; Polyphenols; Tea | 2022 |
Beneficial Effects of Epigallocatechin-3-
Topics: Animals; Antineoplastic Agents; Antioxidants; Catechin; Chlorogenic Acid; Curcumin; Humans; Neurodegenerative Diseases; Neuroprotective Agents; Resveratrol | 2021 |
New insights into the role of the Nrf2 signaling pathway in green tea catechin applications.
Topics: Animals; Apoptosis; Catechin; Humans; Inflammation; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Signal Transduction; Tea | 2021 |
EGCG, a Green Tea Catechin, as a Potential Therapeutic Agent for Symptomatic and Asymptomatic SARS-CoV-2 Infection.
Topics: Antiviral Agents; Binding Sites; Catechin; Coronavirus 3C Proteases; COVID-19; COVID-19 Drug Treatment; Cysteine Proteinase Inhibitors; Humans; SARS-CoV-2; Tea | 2021 |
Role of Phytomolecules in the Treatment of Obesity: Targets, Mechanisms and Limitations.
Topics: Adipokines; Animals; Anthocyanins; Anti-Obesity Agents; Benzoquinones; Catechin; Citrates; Drug Discovery; Drug Therapy, Combination; Energy Metabolism; Enzyme Inhibitors; Flavonoids; Humans; Lipids; Obesity; Phytochemicals; Phytohemagglutinins; Plant Extracts; Plants; Signal Transduction; Tannins | 2021 |
Epigallocatechin Gallate for Management of Heavy Metal-Induced Oxidative Stress: Mechanisms of Action, Efficacy, and Concerns.
Topics: Animals; Biological Availability; Catechin; Environmental Exposure; Humans; Metals, Heavy; Oxidative Stress; Risk Factors | 2021 |
Beneficial Effects of Green Tea Catechins on Female Reproductive Disorders: A Review.
Topics: Angiogenesis Inhibitors; Animals; Antioxidants; Apoptosis; Camellia sinensis; Catechin; Cell Proliferation; Corticosterone; Cross-Sectional Studies; Disease Models, Animal; Dysmenorrhea; Endometriosis; Female; Humans; Mice; Plant Extracts; Polycystic Ovary Syndrome; Tea; Uterus | 2021 |
Green Tea Epigallocatechin-3-gallate (EGCG) Targeting Protein Misfolding in Drug Discovery for Neurodegenerative Diseases.
Topics: alpha-Synuclein; Alzheimer Disease; Amyloid beta-Protein Precursor; Catechin; Drug Discovery; Humans; Molecular Targeted Therapy; Neurodegenerative Diseases; Parkinson Disease; Protein Aggregates; Protein Folding; Tea | 2021 |
Immunomodulatory Effects of Green Tea Polyphenols.
Topics: Animals; Antioxidants; Biological Products; Catechin; Flavonoids; Humans; Immunity; Immunologic Factors; Polyphenols; Tea | 2021 |
Antiviral Effects of Green Tea EGCG and Its Potential Application against COVID-19.
Topics: Animals; Antiviral Agents; Catechin; COVID-19 Drug Treatment; Humans; Tea; Virus Internalization; Viruses | 2021 |
Nutraceuticals in the Mediterranean Diet: Potential Avenues for Breast Cancer Treatment.
Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Catechin; Cell Cycle Checkpoints; Diet, Mediterranean; Dietary Supplements; Fatty Acids, Omega-3; Female; Humans; Inflammation; Polyphenols; Resveratrol; Retinoids | 2021 |
Research progress of epigallocatechin-3-gallate (EGCG) on anti-pathogenic microbes and immune regulation activities.
Topics: Animals; Anti-Infective Agents; Antioxidants; Catechin; Coronavirus; COVID-19 Drug Treatment; Hepatitis Viruses; Humans; Immunologic Factors; Inflammation; Mycobacterium tuberculosis; Orthomyxoviridae; Oxidative Stress; SARS-CoV-2; Virus Replication | 2021 |
Beneficial Effects of Green Tea EGCG on Skin Wound Healing: A Comprehensive Review.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antioxidants; Bandages; Catechin; Cicatrix; Humans; Hydrogels; Skin; Tea; Wound Healing | 2021 |
An Overview on the Potential Roles of EGCG in the Treatment of COVID-19 Infection.
Topics: Antiviral Agents; Catechin; COVID-19; COVID-19 Drug Treatment; Humans; Tea | 2021 |
Multi-target Approaches of Epigallocatechin-3-O-gallate (EGCG) and its Derivatives against Influenza Viruses.
Topics: Antiviral Agents; Camellia sinensis; Catechin; Enzyme Inhibitors; Humans; Orthomyxoviridae; Orthomyxoviridae Infections; Tea | 2022 |
Epigallocatechin-3-Gallate (EGCG): New Therapeutic Perspectives for Neuroprotection, Aging, and Neuroinflammation for the Modern Age.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Catechin; Humans; Neuroinflammatory Diseases; Neuroprotection; Neuroprotective Agents | 2022 |
Effects of Green Tea (-)-Epigallocatechin-3-Gallate (EGCG) on Cardiac Function - A Review of the Therapeutic Mechanism and Potentials.
Topics: Antioxidants; Calcium; Cardiovascular Diseases; Catechin; Heart Diseases; Humans; Inflammation; Tea | 2022 |
Epigallocatechin gallate: Phytochemistry, bioavailability, utilization challenges, and strategies.
Topics: Biological Availability; Catechin; Humans; Silicon Dioxide; Tea | 2022 |
Chemico-biological aspects of
Topics: Biological Availability; Catechin; Humans; Permeability; Tea | 2023 |
The Potential of Epigallocatechin Gallate (EGCG) in Targeting Autophagy for Cancer Treatment: A Narrative Review.
Topics: Apoptosis; Autophagy; Catechin; Humans; Neoplasms; Phosphatidylinositol 3-Kinases; Tea | 2022 |
Redox and Other Biological Activities of Tea Catechins That May Affect Health: Mechanisms and Unresolved Issues.
Topics: Animals; Catechin; Oxidation-Reduction; Quinones; Tea | 2022 |
Epigallocatechin gallate for Parkinson's disease.
Topics: Animals; Catechin; Humans; Neuroprotective Agents; Parkinson Disease; Tea | 2022 |
The Association Between the Risk of Breast Cancer and Epigallocatechin- 3-Gallate Intake: A Literature Review of a Potential Chemopreventive Agent.
Topics: Anticarcinogenic Agents; Apoptosis; Breast Neoplasms; Catechin; ErbB Receptors; Female; Humans; Tea | 2022 |
Effects of the green tea catechin epigallocatechin-3-gallate on S
Topics: Adenosine Triphosphatases; Biofilms; Catechin; Lactate Dehydrogenases; Plankton; Polysaccharides; Streptococcus mutans; Tea; Virulence Factors | 2022 |
The applications of epigallocatechin gallate (EGCG)-nanogold conjugate in cancer therapy.
Topics: Biological Availability; Catechin; Drug Delivery Systems; Humans; Neoplasms; Tea | 2023 |
Therapeutic Effects of Green Tea Polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in Relation to Molecular Pathways Controlling Inflammation, Oxidative Stress, and Apoptosis.
Topics: Apoptosis; Catechin; Humans; Inflammation; Oxidative Stress; Polyphenols; Tea | 2022 |
Effects of Epigallocatechin-3-Gallate on Matrix Metalloproteinases in Terms of Its Anticancer Activity.
Topics: Antineoplastic Agents; Catechin; Matrix Metalloproteinases; NF-kappa B; Signal Transduction; Tea | 2023 |
EGCG adjuvant chemotherapy: Current status and future perspectives.
Topics: Adjuvants, Immunologic; Animals; Apoptosis; Catechin; Cell Line, Tumor; Cisplatin; Doxorubicin; Mice; Neoplasms; Quality of Life | 2023 |
Mechanisms Underlying the Effects of the Green Tea Polyphenol EGCG in Sarcopenia Prevention and Management.
Topics: Animals; Catechin; Humans; Polyphenols; Sarcopenia; Tea | 2023 |
The Potential Role of Epigallocatechin-3-Gallate (EGCG) in Breast Cancer Treatment.
Topics: Apoptosis; Breast; Breast Neoplasms; Catechin; Female; Humans; Polyphenols; Signal Transduction; Tea | 2023 |
Epigallocatechin-3-Gallate Therapeutic Potential in Cancer: Mechanism of Action and Clinical Implications.
Topics: Apoptosis; Catechin; Humans; Neoplasms; NF-kappa B; Phosphatidylinositol 3-Kinases; Signal Transduction; Tea | 2023 |
Therapeutic Activity of Green Tea Epigallocatechin-3-Gallate on Metabolic Diseases and Non-Alcoholic Fatty Liver Diseases: The Current Updates.
Topics: Antioxidants; Catechin; Diabetes Mellitus, Type 2; Humans; Metabolic Diseases; Non-alcoholic Fatty Liver Disease; Obesity; Polyphenols; Tea | 2023 |
Cardioprotective effect of epigallocatechin gallate in myocardial ischemia/reperfusion injury and myocardial infarction: a meta-analysis in preclinical animal studies.
Topics: Animals; Animals, Laboratory; Catechin; Myocardial Infarction; Myocardial Reperfusion Injury | 2023 |
Tea-break with epigallocatechin gallate derivatives - Powerful polyphenols of great potential for medicine.
Topics: Antioxidants; Camellia sinensis; Catechin; Polyphenols; Tea | 2023 |
163 trial(s) available for catechin and epigallocatechin gallate
| Article | Year |
|---|---|
Analysis of (-)-epigallocatechin gallate in human serum obtained after ingesting green tea.
Topics: Antimutagenic Agents; Antineoplastic Agents, Phytogenic; Catechin; Chromatography, High Pressure Liquid; Electrochemistry; Free Radical Scavengers; Humans; Tea | 1996 |
Green tea and leukoplakia. The Indian-US Head and Neck Cancer Cooperative Group.
Topics: Adult; Aged; Antineoplastic Agents; Catechin; Chemoprevention; Feasibility Studies; Female; Head and Neck Neoplasms; Humans; India; Leukoplakia, Oral; Male; Middle Aged; Patient Compliance; Risk Factors; Tea | 1997 |
Dose-dependent incorporation of tea catechins, (-)-epigallocatechin-3-gallate and (-)-epigallocatechin, into human plasma.
Topics: Adult; Antioxidants; beta Carotene; Beverages; Carotenoids; Catechin; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Flavonoids; Free Radical Scavengers; Humans; Lipids; Lycopene; Male; Plant Extracts; Tea; Vitamin E | 1997 |
Relationship between rate and extent of catechin absorption and plasma antioxidant status.
Topics: Adult; Antioxidants; Ascorbic Acid; beta Carotene; Biomarkers; Catechin; Dietary Supplements; Glutathione; Humans; Male; Phospholipids; Tea; Time Factors; Vitamin E | 1998 |
Phase I pharmacokinetic study of tea polyphenols following single-dose administration of epigallocatechin gallate and polyphenon E.
Topics: Administration, Oral; Adult; Anticarcinogenic Agents; Area Under Curve; Beverages; Catechin; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged | 2001 |
Catechins are bioavailable in men and women drinking black tea throughout the day.
Topics: Adult; Biological Availability; Catechin; Chromatography, High Pressure Liquid; Drinking; Feces; Female; Humans; Male; Middle Aged; Plant Extracts; Stereoisomerism; Tea | 2001 |
Plasma concentrations of individual tea catechins after a single oral dose in humans.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antioxidants; Area Under Curve; Catechin; Female; Humans; Male; Middle Aged; Random Allocation; Tea; Uric Acid | 2001 |
Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals.
Topics: Adult; Catechin; Dose-Response Relationship, Drug; Erythema; Female; Flavonoids; Free Radical Scavengers; Humans; Male; Middle Aged; Phenols; Placebos; Polyphenols; Tea; Time Factors; Ultraviolet Rays | 2003 |
Protective effects of green tea extracts (polyphenon E and EGCG) on human cervical lesions.
Topics: Administration, Oral; Administration, Topical; Adult; Antineoplastic Agents, Phytogenic; Catechin; Female; Humans; Papillomaviridae; Papillomavirus Infections; Tea; Urokinase-Type Plasminogen Activator; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms; Uterine Cervicitis | 2003 |
Plasma-kinetic characteristics of purified and isolated green tea catechin epigallocatechin gallate (EGCG) after 10 days repeated dosing in healthy volunteers.
Topics: Adolescent; Adult; Camellia sinensis; Catechin; Double-Blind Method; Half-Life; Humans; Kinetics; Male; Middle Aged; Placebos; Plant Leaves | 2004 |
Bioavailability and antioxidant activity of tea flavanols after consumption of green tea, black tea, or a green tea extract supplement.
Topics: Administration, Oral; Adult; Antioxidants; Beverages; Biological Availability; Caffeine; Catechin; Cross-Over Studies; Dietary Supplements; Female; Flavonoids; Flavonols; Humans; Intestinal Absorption; Male; Phenols; Polyphenols; Tea | 2004 |
Epigallocatechin gallate (EGCG) (TEAVIGO) does not impair nonhaem-iron absorption in man.
Topics: Administration, Oral; Adolescent; Adult; Antioxidants; Camellia sinensis; Catechin; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Female; Humans; Injections, Intravenous; Intestinal Absorption; Iron; Iron Isotopes; Middle Aged; Phytotherapy | 2005 |
Effects of encapsulated green tea and Guarana extracts containing a mixture of epigallocatechin-3-gallate and caffeine on 24 h energy expenditure and fat oxidation in men.
Topics: Adult; Analysis of Variance; Area Under Curve; Beverages; Caffeine; Calorimetry, Indirect; Catechin; Central Nervous System Stimulants; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Energy Metabolism; Humans; Male; Middle Aged; Oxidation-Reduction; Paullinia; Plant Extracts; Tea; Thermogenesis | 2005 |
Oral administration of a decaffeinated green tea (Camellia sinensis) extract did not alter urinary 8-epi-prostaglandin F(2 alpha), a biomarker for in-vivo lipid peroxidation.
Topics: Administration, Oral; Adult; Biomarkers; Camellia sinensis; Capsules; Catechin; Chromatography, High Pressure Liquid; Creatinine; Dinoprost; Female; Flavonoids; Humans; Lipid Peroxidation; Male; Middle Aged; Pilot Projects; Plant Extracts; Tea; Time Factors | 2005 |
Tea polyphenols and theaflavins are present in prostate tissue of humans and mice after green and black tea consumption.
Topics: Aged; Animals; Anticarcinogenic Agents; Antioxidants; Biflavonoids; Biological Availability; Catechin; Chromatography, High Pressure Liquid; Flavonoids; Humans; Male; Mice; Mice, Inbred C57BL; Middle Aged; Phenols; Polyphenols; Prostate; Prostatic Neoplasms; Tea; Tissue Distribution; Tumor Cells, Cultured | 2006 |
Human hair growth enhancement in vitro by green tea epigallocatechin-3-gallate (EGCG).
Topics: Administration, Topical; Alopecia; bcl-2-Associated X Protein; Catechin; Cells, Cultured; Dermis; Gene Expression Regulation; Hair; Hair Follicle; Humans; Male; Phytotherapy; Proto-Oncogene Proteins c-bcl-2; Scalp; Tea; Tissue Culture Techniques | 2007 |
Acute EGCG supplementation reverses endothelial dysfunction in patients with coronary artery disease.
Topics: Administration, Oral; Antioxidants; Beverages; Blood Flow Velocity; Brachial Artery; Catechin; Coronary Artery Disease; Cross-Over Studies; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Tea; Vasodilation | 2007 |
The effects of epigallocatechin-3-gallate on thermogenesis and fat oxidation in obese men: a pilot study.
Topics: Adipose Tissue; Adult; Antioxidants; Basal Metabolism; Catechin; Cross-Over Studies; Double-Blind Method; Energy Metabolism; Humans; Male; Obesity; Oxidation-Reduction; Oxygen Consumption; Pilot Projects; Plant Extracts; Tea; Thermogenesis; Weight Loss | 2007 |
Can EGCG reduce abdominal fat in obese subjects?
Topics: Abdominal Fat; Aged; Blood Glucose; Body Composition; Body Mass Index; Catechin; Dietary Supplements; Female; Health Status; Heart Rate; Humans; Middle Aged; Obesity; Overweight; Postmenopause; Treatment Outcome; Waist-Hip Ratio; Walking; Weight Loss | 2007 |
Limited sampling strategies to estimate exposure to the green tea polyphenol, epigallocatechin gallate, in fasting and fed conditions.
Topics: Camellia sinensis; Catechin; Cross-Over Studies; Eating; Fasting; Humans; Tea; Time Factors | 2007 |
Prospective cohort comparison of flavonoid treatment in patients with resected colorectal cancer to prevent recurrence.
Topics: Aged; Aged, 80 and over; Apigenin; Catechin; Cohort Studies; Colon; Colorectal Neoplasms; Female; Flavonoids; Humans; Male; Middle Aged; Prospective Studies; Recurrence; Surveys and Questionnaires | 2008 |
Effect of nutrient mixture and black grapes on the pharmacokinetics of orally administered (-)epigallocatechin-3-gallate from green tea extract: a human study.
Topics: Administration, Oral; Adult; Antioxidants; Biological Availability; Catechin; Female; Food; Humans; Male; Plant Extracts; Tea; Vitis | 2008 |
Administration of a dietary supplement ( N-oleyl-phosphatidylethanolamine and epigallocatechin-3-gallate formula) enhances compliance with diet in healthy overweight subjects: a randomized controlled trial.
Topics: Adolescent; Adult; Appetite Depressants; Biomarkers; Blood Glucose; Body Composition; Catechin; Depression; Diet, Reducing; Dietary Supplements; Double-Blind Method; Eating; Female; Humans; Insulin; Male; Middle Aged; Overweight; Patient Compliance; Phosphatidylethanolamines; Satiation; Statistics, Nonparametric; Weight Loss | 2009 |
Effects of dietary supplementation with the green tea polyphenol epigallocatechin-3-gallate on insulin resistance and associated metabolic risk factors: randomized controlled trial.
Topics: Adult; Affect; Aged; Antihypertensive Agents; Catechin; Diastole; Dietary Supplements; Double-Blind Method; Glucose Tolerance Test; Humans; Insulin Resistance; Male; Metabolic Syndrome; Middle Aged; Obesity; Phytotherapy; Treatment Failure | 2009 |
Epigallocatechin-3-gallate supplementation can improve antioxidant status in stressed quail.
Topics: Animal Feed; Animals; Antioxidants; Blood Glucose; Catechin; Cholesterol; Coturnix; Diet; Dietary Supplements; Hot Temperature; Malondialdehyde; Stress, Physiological; Triglycerides; Weight Gain | 2008 |
Pure dietary flavonoids quercetin and (-)-epicatechin augment nitric oxide products and reduce endothelin-1 acutely in healthy men.
Topics: Adult; Catechin; Cross-Over Studies; Diet; Endothelin-1; Endothelium, Vascular; F2-Isoprostanes; Flavonoids; Humans; Intestinal Absorption; Male; Nitrates; Nitric Oxide; Nitrites; Oxidative Stress; Quercetin; S-Nitrosothiols | 2008 |
Green tea catechin plus caffeine supplementation to a high-protein diet has no additional effect on body weight maintenance after weight loss.
Topics: Adolescent; Adult; Appetite; Blood Glucose; Body Composition; Body Weight; Caffeine; Catechin; Dietary Proteins; Fatty Acids, Nonesterified; Female; Glycerol; Humans; Insulin; Leptin; Male; Middle Aged; Tea; Thermogenesis; Triglycerides; Weight Loss; Young Adult | 2009 |
Effect of epigallocatechin-gallate on inner retinal function in ocular hypertension and glaucoma: a short-term study by pattern electroretinogram.
Topics: Adult; Aged; Antioxidants; Catechin; Cross-Over Studies; Double-Blind Method; Electroretinography; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Pattern Recognition, Visual; Retinal Ganglion Cells; Visual Field Tests; Visual Fields | 2009 |
Supplementation with lutein or lutein plus green tea extracts does not change oxidative stress in adequately nourished older adults.
Topics: Aged; Antioxidants; Catechin; Dietary Supplements; Female; Flavonols; Humans; Lipid Peroxidation; Lutein; Male; Malondialdehyde; Middle Aged; Models, Biological; Oxidative Stress; Tea | 2010 |
Phase I trial of daily oral Polyphenon E in patients with asymptomatic Rai stage 0 to II chronic lymphocytic leukemia.
Topics: Administration, Oral; Adult; Aged; Anticarcinogenic Agents; Catechin; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasm Staging; Patient Selection; Tea; Treatment Outcome | 2009 |
Effects of quercetin and EGCG on mitochondrial biogenesis and immunity.
Topics: Adult; Antioxidants; C-Reactive Protein; Catechin; Dietary Supplements; Docosahexaenoic Acids; Double-Blind Method; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Female; Granulocyte Colony-Stimulating Factor; Humans; Interleukin-10; Interleukin-6; Male; Mitochondria; Oxidative Stress; PPAR gamma; Quercetin; RNA, Messenger | 2009 |
Epigallocatechin-3-gallate increases maximal oxygen uptake in adult humans.
Topics: Adult; Antioxidants; Catechin; Double-Blind Method; Female; Humans; Male; Maximal Voluntary Ventilation; Oxygen Consumption; Physical Endurance; Young Adult | 2010 |
Antihypertensive effect of Benifuuki tea containing O-methylated EGCG.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Camellia sinensis; Catechin; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Plant Extracts; Tea | 2010 |
The effects of EGCG on fat oxidation and endurance performance in male cyclists.
Topics: Adult; Antioxidants; Bicycling; Caffeine; Catechin; Cross-Over Studies; Double-Blind Method; Humans; Lipid Metabolism; Male; Oxygen Consumption; Physical Endurance | 2009 |
Epigallocatechin-3-gallate and postprandial fat oxidation in overweight/obese male volunteers: a pilot study.
Topics: Adult; Antioxidants; Caffeine; Catechin; Cross-Over Studies; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Energy Metabolism; Fasting; Humans; Lipid Peroxidation; Male; Obesity; Overweight; Pilot Projects; Plant Extracts; Postprandial Period; Young Adult | 2010 |
Critical need for clinical trials: an example of a pilot human intervention trial of a mixture of natural agents protecting lymphocytes against TNF-alpha induced activation of NF-kappaB.
Topics: Adult; Biological Products; Catechin; Curcumin; DNA; Female; Humans; Isoflavones; Lymphocytes; Male; Middle Aged; Neoplasms; NF-kappa B; Oxidative Stress; Tumor Necrosis Factor-alpha; Young Adult | 2010 |
Effect of gender on the metabolic impact of a commercially available thermogenic drink.
Topics: Adipose Tissue; Adult; Beverages; Body Composition; Caffeine; Catechin; Energy Metabolism; Exercise; Fatty Acids, Nonesterified; Female; Glycerol; Humans; Male; Sex Factors; Taurine; Weight Loss; Young Adult | 2010 |
Green tea supplementation affects body weight, lipids, and lipid peroxidation in obese subjects with metabolic syndrome.
Topics: Adult; Aldehydes; Biological Availability; Body Mass Index; Body Weight; Camellia sinensis; Case-Control Studies; Catechin; Cholesterol; Female; Humans; Hypolipidemic Agents; Lipid Peroxidation; Male; Malondialdehyde; Metabolic Syndrome; Obesity; Patient Compliance; Phytotherapy; Plant Extracts; Single-Blind Method | 2010 |
Green tea minimally affects biomarkers of inflammation in obese subjects with metabolic syndrome.
Topics: Adult; Antioxidants; Biomarkers; C-Reactive Protein; Camellia sinensis; Cardiovascular Diseases; Catechin; Female; Humans; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1beta; Interleukin-6; Male; Metabolic Syndrome; Middle Aged; Obesity; Phytotherapy; Plant Extracts; Single-Blind Method; Tea; Vascular Cell Adhesion Molecule-1 | 2011 |
Influence of short-term consumption of the caffeine-free, epigallocatechin-3-gallate supplement, Teavigo, on resting metabolism and the thermic effect of feeding.
Topics: Adult; Antioxidants; Area Under Curve; Basal Metabolism; Beverages; Catechin; Dietary Supplements; Energy Metabolism; Female; Humans; Male; Overweight; Tea; Thermogenesis; Treatment Outcome | 2011 |
Anti-angiogenic effects of epigallocatechin-3-gallate in human skin.
Topics: Administration, Cutaneous; Adult; Angiogenesis Inhibitors; Catechin; Dosage Forms; Double-Blind Method; Erythema; Face; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Male; Middle Aged; Neovascularization, Pathologic; Skin; Telangiectasis; Vascular Endothelial Growth Factor A | 2010 |
Physiological effects of caffeine, epigallocatechin-3-gallate, and exercise in overweight and obese women.
Topics: Adolescent; Adult; Antioxidants; Body Composition; Caffeine; Cardiovascular Physiological Phenomena; Catechin; Combined Modality Therapy; Exercise; Female; Humans; Lipids; Middle Aged; Obesity; Phosphodiesterase Inhibitors; Physical Endurance; Physical Fitness; Young Adult | 2010 |
Pecans acutely increase plasma postprandial antioxidant capacity and catechins and decrease LDL oxidation in humans.
Topics: Adult; Antioxidants; Carya; Catechin; Cross-Over Studies; Female; Humans; Lipid Peroxidation; Lipoproteins, LDL; Male; Postprandial Period; Tocopherols; Young Adult | 2011 |
A preliminary investigation of the impact of catechol-O-methyltransferase genotype on the absorption and metabolism of green tea catechins.
Topics: Amino Acid Substitution; Catechin; Catechol O-Methyltransferase; Dietary Supplements; Female; Genetic Association Studies; Homozygote; Humans; Intestinal Absorption; Kinetics; Male; Methylation; Middle Aged; Phenols; Pilot Projects; Plant Extracts; Polymorphism, Single Nucleotide; Tea | 2012 |
Does supplementation with green tea extract improve insulin resistance in obese type 2 diabetics? A randomized, double-blind, and placebo-controlled clinical trial.
Topics: Adult; Antioxidants; Body Mass Index; Catechin; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Insulin Resistance; Lipid Metabolism; Male; Middle Aged; Obesity; Prospective Studies; Tea; Treatment Outcome; Waist-Hip Ratio; Weight Loss; Young Adult | 2011 |
Health effects of green tea catechins in overweight and obese men: a randomised controlled cross-over trial.
Topics: Adult; Aged; Alleles; Base Sequence; Biomarkers; Cardiotonic Agents; Catechin; Catechol O-Methyltransferase; Cross-Over Studies; DNA Primers; Double-Blind Method; Genotype; Humans; Male; Middle Aged; Obesity; Overweight; Tea | 2011 |
[Clinical effectiveness of N-oleyl-phosphatidyl-ethanolamine (NOPE) in obesity: our experience].
Topics: Adult; Antioxidants; Appetite Depressants; Body Mass Index; Catechin; Female; Humans; Middle Aged; Obesity, Morbid; Phosphatidylethanolamines; Treatment Outcome | 2011 |
Protocol for minimizing the risk of metachronous adenomas of the colorectum with green tea extract (MIRACLE): a randomised controlled trial of green tea extract versus placebo for nutriprevention of metachronous colon adenomas in the elderly population.
Topics: Adenoma; Aged; Aged, 80 and over; Camellia sinensis; Catechin; Colonic Neoplasms; Colonoscopy; Dietary Supplements; Double-Blind Method; Humans; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Placebos; Plant Extracts | 2011 |
Acute neurocognitive effects of epigallocatechin gallate (EGCG).
Topics: Affect; Aged; Aged, 80 and over; Brain; Camellia sinensis; Catechin; Cognition; Cross-Over Studies; Double-Blind Method; Electroencephalography; Female; Humans; Male; Middle Aged; Placebos; Plant Extracts; Tea | 2012 |
Effect of 2-month controlled green tea intervention on lipoprotein cholesterol, glucose, and hormone levels in healthy postmenopausal women.
Topics: Androgens; Catechin; Cholesterol; Double-Blind Method; Estrogens; Female; Glucose; Humans; Lipoproteins; Middle Aged; Postmenopause; Prognosis; Sex Hormone-Binding Globulin; Tea; Time Factors; Women's Health | 2012 |
Simultaneous ingestion of dietary proteins reduces the bioavailability of galloylated catechins from green tea in humans.
Topics: Adult; Antioxidants; Biological Availability; Body Mass Index; Catechin; Chromatography, High Pressure Liquid; Cross-Over Studies; Dietary Proteins; Female; Humans; Surveys and Questionnaires; Tea; Young Adult | 2013 |
Epigallocatechin gallate, cerebral blood flow parameters, cognitive performance and mood in healthy humans: a double-blind, placebo-controlled, crossover investigation.
Topics: Administration, Oral; Adolescent; Adult; Affect; Catechin; Cerebral Cortex; Cognition; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Hemoglobins; Humans; Male; Neuroprotective Agents; Oxyhemoglobins; Spectroscopy, Near-Infrared; Young Adult | 2012 |
Epigallocatechin-3-gallate (EGCG) enhances the therapeutic activity of a dental adhesive.
Topics: Anti-Bacterial Agents; Antioxidants; Biofilms; Catechin; Chemical Phenomena; Composite Resins; Dental Bonding; Dental Cements; Dental Materials; Dentin; Humans; Materials Testing; Microscopy, Electron, Scanning; Polymerization; Spectroscopy, Fourier Transform Infrared; Streptococcus mutans; Stress, Mechanical; Surface Properties; Temperature; Tensile Strength; Time Factors; Water | 2012 |
Effects of green tea supplementation on elements, total antioxidants, lipids, and glucose values in the serum of obese patients.
Topics: Adult; Antioxidants; Blood Glucose; Catechin; Dietary Supplements; Female; Humans; Lipids; Male; Middle Aged; Obesity; Oxidative Stress; Tea | 2012 |
Green tea halts progression of cardiac transthyretin amyloidosis: an observational report.
Topics: Aged; Amyloid Neuropathies, Familial; Cardiomyopathies; Catechin; Cholesterol; Cohort Studies; Disease Progression; Female; Follow-Up Studies; Heart Ventricles; Humans; Male; Middle Aged; Mitral Valve; Plant Extracts; Tea | 2012 |
A new in vivo Raman probe for enhanced applicability to the body.
Topics: Adult; Axilla; Catechin; Epidermis; Equipment Design; Female; Forearm; Humans; Lipids; Male; Middle Aged; Mouth Mucosa; Organ Specificity; Scalp; Spectrum Analysis, Raman; Young Adult | 2012 |
The effect of a dietary supplement (N-oleyl-phosphatidyl-ethanolamine and epigallocatechin gallate) on dietary compliance and body fat loss in adults who are overweight: a double-blind, randomized control trial.
Topics: Adipose Tissue; Adult; Affect; Anti-Obesity Agents; Catechin; Diet, Reducing; Dietary Supplements; Double-Blind Method; Female; Humans; Male; Middle Aged; Overweight; Patient Compliance; Phosphatidylethanolamines; Time Factors; Treatment Outcome; Young Adult | 2012 |
Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes.
Topics: Acne Vulgaris; AMP-Activated Protein Kinases; Antioxidants; Apoptosis; Catechin; Cell Line, Transformed; Child; Dermatitis; Double-Blind Method; Female; Gram-Positive Bacterial Infections; Humans; Lipogenesis; Male; NF-kappa B; Propionibacterium acnes; Sebum; Signal Transduction; Transcription Factor AP-1; Treatment Outcome | 2013 |
Limited sampling estimates of epigallocatechin gallate exposures in cirrhotic and noncirrhotic patients with hepatitis C after single oral doses of green tea extract.
Topics: Administration, Oral; Aged; Antioxidants; Area Under Curve; Catechin; Female; Follow-Up Studies; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Male; Middle Aged; Plant Extracts; Tea; Time Factors | 2012 |
[Pilot study of the effect of green tea extractive epigallocatechin-3-gallate on degradation of collagen in dental erosion].
Topics: Catechin; Collagen; Humans; Pilot Projects; Tea | 2012 |
Effects of green tea extracts on non-shivering thermogenesis during mild cold exposure in young men.
Topics: Adult; Area Under Curve; Caffeine; Camellia sinensis; Catechin; Cold Temperature; Diabetes Mellitus; Diet; Energy Metabolism; Humans; Male; Obesity; Plant Extracts; Shivering; Tea; Thermogenesis; Young Adult | 2013 |
No effect of 1 or 7 d of green tea extract ingestion on fat oxidation during exercise.
Topics: Adipose Tissue; Adolescent; Adult; Catechin; Double-Blind Method; Exercise; Fatty Acids; Female; Glycerol; Humans; Lipolysis; Male; Oxygen Consumption; Plant Extracts; Protease Inhibitors; Young Adult | 2013 |
Epigallocatechin gallate attenuates interstitial cystitis in human bladder urothelium cells by modulating purinergic receptors.
Topics: Adenosine Triphosphate; Antioxidants; Case-Control Studies; Catechin; Cells, Cultured; Cystitis, Interstitial; Epithelial Cells; Female; Humans; Nitric Oxide Synthase Type II; Receptors, Purinergic; Urothelium | 2013 |
Improvement in insulin resistance and favourable changes in plasma inflammatory adipokines after weight loss associated with two months' consumption of a combination of bioactive food ingredients in overweight subjects.
Topics: Adipokines; Adult; Alkaloids; Benzodioxoles; Capsaicin; Carnitine; Catechin; Diet, Reducing; Dietary Supplements; Double-Blind Method; Female; Humans; Inflammation Mediators; Insulin Resistance; Male; Middle Aged; Overweight; Piperidines; Polyunsaturated Alkamides; Time Factors; Weight Loss; Young Adult | 2013 |
Phenolic acid concentrations in plasma and urine from men consuming green or black tea and potential chemopreventive properties for colon cancer.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Camellia sinensis; Catechin; Cell Proliferation; Chromatography, High Pressure Liquid; Colonic Neoplasms; Gallic Acid; HCT116 Cells; Hippurates; Humans; Hydroxybenzoates; Lactones; Male; Middle Aged; Phenylacetates; Prostatic Neoplasms; Tea | 2013 |
Dose-response plasma appearance of green tea catechins in adults.
Topics: Adolescent; Adult; Aged; Biological Availability; Catechin; Chromatography, Liquid; Cross-Over Studies; Enterohepatic Circulation; Female; Humans; Male; Middle Aged; Plant Extracts; Plant Leaves; Tandem Mass Spectrometry; Tea; Young Adult | 2013 |
A pilot study to evaluate the safety and efficacy of an oral dose of (-)-epigallocatechin-3-gallate-rich polyphenon E in patients with mild to moderate ulcerative colitis.
Topics: Administration, Oral; Adolescent; Adult; Biological Availability; Catechin; Colitis, Ulcerative; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pilot Projects; Prognosis; Quality of Life; Remission Induction; Tea; Young Adult | 2013 |
EGCG-rich green tea extract stimulates sRAGE secretion to inhibit S100A12-RAGE axis through ADAM10-mediated ectodomain shedding of extracellular RAGE in type 2 diabetes.
Topics: ADAM Proteins; ADAM10 Protein; Amyloid Precursor Protein Secretases; Camellia sinensis; Catechin; Diabetes Mellitus, Type 2; Female; Humans; Male; Membrane Proteins; Middle Aged; Monocytes; Plant Extracts; Protein Structure, Tertiary; Receptor for Advanced Glycation End Products; Receptors, Immunologic; S100 Proteins; S100A12 Protein | 2013 |
A two-stage, single-arm, phase II study of EGCG-enriched green tea drink as a maintenance therapy in women with advanced stage ovarian cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Endometrioid; Catechin; Combined Modality Therapy; Cystadenocarcinoma, Serous; Disease-Free Survival; Female; Humans; Maintenance Chemotherapy; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Ovarian Neoplasms; Taxoids; Tea | 2013 |
Acute effect on satiety, resting energy expenditure, respiratory quotient, glucagon-like peptide-1, free fatty acids, and glycerol following consumption of a combination of bioactive food ingredients in overweight subjects.
Topics: Adult; Alkaloids; Area Under Curve; Basal Metabolism; Benzodioxoles; Capsaicin; Carnitine; Catechin; Dietary Supplements; Double-Blind Method; Fatty Acids, Nonesterified; Female; Glucagon-Like Peptide 1; Glycerol; Humans; Male; Middle Aged; Obesity; Phytotherapy; Piperidines; Plant Extracts; Polyunsaturated Alkamides; Satiation; Satiety Response | 2013 |
Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans.
Topics: Adolescent; Adult; Animals; Biomarkers; Catechin; Chromosomes, Human, Pair 16; Cognition; Disease Models, Animal; Double-Blind Method; Down Syndrome; Dyrk Kinases; Female; Gene Expression Regulation; Hippocampus; Humans; Male; Mice; Mice, Transgenic; Mosaicism; Phosphorylation; Pilot Projects; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Trisomy; Young Adult | 2014 |
Variable duration of decaffeinated green tea extract ingestion on exercise metabolism.
Topics: Adipose Tissue; Adult; Camellia sinensis; Carbohydrate Metabolism; Catechin; Cross-Over Studies; Energy Metabolism; Exercise; Fatty Acids; Glycerol; Humans; Male; Oxidation-Reduction; Plant Extracts; Tea | 2014 |
The effects of bathing in hot springs on the absorption of green tea catechin: a pilot study.
Topics: Adult; Baths; Biological Availability; Camellia sinensis; Catechin; Female; Hot Springs; Humans; Intestinal Absorption; Male; Pilot Projects; Plant Extracts | 2013 |
Effects of dietary supplementation with epigallocatechin-3-gallate on weight loss, energy homeostasis, cardiometabolic risk factors and liver function in obese women: randomised, double-blind, placebo-controlled clinical trial.
Topics: Adult; Anti-Obesity Agents; Antioxidants; Body Mass Index; Camellia sinensis; Catechin; Diet, Reducing; Dietary Supplements; Double-Blind Method; Energy Metabolism; Female; Humans; Insulin Resistance; Liver; Metabolic Syndrome; Middle Aged; Obesity; Plant Extracts; Plant Leaves; Risk Factors; Spain; Young Adult | 2014 |
Short-term supplementation with a specific combination of dietary polyphenols increases energy expenditure and alters substrate metabolism in overweight subjects.
Topics: Adult; Antioxidants; Body Mass Index; Catechin; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Energy Metabolism; Female; Humans; Lipid Metabolism; Male; Middle Aged; Overweight; Oxidation-Reduction; Polyphenols; Postprandial Period; Resveratrol; Stilbenes; Treatment Outcome | 2014 |
A phase I study of concurrent chemotherapy and thoracic radiotherapy with oral epigallocatechin-3-gallate protection in patients with locally advanced stage III non-small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Catechin; Chemoradiotherapy; Cisplatin; Esophagitis; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Radiotherapy Dosage | 2014 |
'Benifuuki' green tea containing o-methylated catechin reduces symptoms of Japanese cedar pollinosis: a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Aged; Allergens; Catechin; Cryptomeria; Female; Humans; Male; Medication Adherence; Middle Aged; Pollen; Rhinitis, Allergic, Seasonal; Seasons; Tea; Treatment Outcome; Young Adult | 2014 |
The effect of three weeks green tea extract consumption on blood pressure, heart rate responses to a single bout resistance exercise in hypertensive women.
Topics: Adult; Analysis of Variance; Antioxidants; Blood Pressure; Cardiovascular Diseases; Catechin; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Hypertension; Middle Aged; Plant Extracts; Resistance Training; Risk Factors; Tea; Treatment Outcome | 2014 |
The activity of catechol-O-methyltransferase (COMT) is not impaired by high doses of epigallocatechin-3-gallate (EGCG) in vivo.
Topics: Catechin; Catechol O-Methyltransferase; Cells, Cultured; Erythrocytes; Female; Gene Frequency; Genotype; Humans; Male; Polymorphism, Single Nucleotide | 2014 |
Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation.
Topics: Adaptor Proteins, Signal Transducing; Administration, Oral; Adolescent; Adult; Animals; Apoptosis Regulatory Proteins; Beclin-1; Catechin; Cell Membrane; Child; Chlorides; Cystamine; Cysteamine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Homozygote; Humans; Interleukin-8; Male; Membrane Proteins; Mice; Mice, Inbred CFTR; Mice, Transgenic; Mutation; Phenotype; Pilot Projects; Sequestosome-1 Protein; Tumor Necrosis Factor-alpha; Young Adult | 2014 |
Effects of rye bread enriched with green tea extract on weight maintenance and the characteristics of metabolic syndrome following weight loss: a pilot study.
Topics: Blood Pressure; Body Mass Index; Body Weight Maintenance; Bread; Caffeine; Camellia sinensis; Catechin; Diet, Reducing; Edible Grain; Energy Intake; Female; Humans; Male; Metabolic Syndrome; Middle Aged; Obesity; Phytotherapy; Plant Extracts; Secale; Single-Blind Method; Waist Circumference; Weight Loss | 2015 |
Effects of epigallocatechin gallate on lipid metabolism and its underlying molecular mechanism in broiler chickens.
Topics: Abdominal Fat; Animal Nutritional Physiological Phenomena; Animals; Catechin; Chickens; Gene Expression Regulation; Lipid Metabolism; Liver; Male; Molecular Sequence Data; Real-Time Polymerase Chain Reaction; RNA; Weight Gain | 2015 |
Metabolic response to epigallocatechin-3-gallate in relapsing-remitting multiple sclerosis: a randomized clinical trial.
Topics: Adult; Carbohydrate Metabolism; Catechin; Combined Modality Therapy; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Energy Metabolism; Female; Glatiramer Acetate; Humans; Immunosuppressive Agents; Lipid Metabolism; Male; Middle Aged; Motor Activity; Multiple Sclerosis, Relapsing-Remitting; Muscle, Skeletal; Neuroprotective Agents; Peptides; Postprandial Period; Severity of Illness Index; Sex Characteristics; Subcutaneous Fat, Abdominal | 2015 |
A prospective phase II trial of EGCG in treatment of acute radiation-induced esophagitis for stage III lung cancer.
Topics: Adult; Aged; Catechin; Esophagitis; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Prospective Studies; Quality of Life; Radiation Injuries | 2015 |
Extracellular remodeling in patients with wild-type amyloidosis consuming epigallocatechin-3-gallate: preliminary results of T1 mapping by cardiac magnetic resonance imaging in a small single center study.
Topics: Administration, Oral; Aged; Amyloid; Amyloidosis; Camellia sinensis; Capsules; Cardiomyopathies; Catechin; Contrast Media; Extracellular Matrix; Fibrosis; Gadolinium DTPA; Germany; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging, Cine; Male; Myocardium; Plant Extracts; Predictive Value of Tests; Time Factors; Treatment Outcome; Ventricular Remodeling | 2015 |
The safety of green tea extract supplementation in postmenopausal women at risk for breast cancer: results of the Minnesota Green Tea Trial.
Topics: Aged; Anticarcinogenic Agents; Antioxidants; Biomarkers; Breast Density; Breast Neoplasms; Camellia sinensis; Catechin; Dietary Supplements; Double-Blind Method; Female; Food Handling; Hepatic Insufficiency; Humans; Mammary Glands, Human; Middle Aged; Minnesota; Plant Extracts; Plant Leaves; Radiography; Risk Factors; Severity of Illness Index | 2015 |
Therapeutic effect of high-dose green tea extract on weight reduction: A randomized, double-blind, placebo-controlled clinical trial.
Topics: Adult; Anti-Obesity Agents; Body Mass Index; Camellia sinensis; Catechin; Dietary Supplements; Double-Blind Method; Female; Food Preservation; Ghrelin; Humans; Hyperlipidemias; Hypolipidemic Agents; Middle Aged; Obesity, Abdominal; Oxidation-Reduction; Patient Dropouts; Plant Extracts; Plant Leaves; Taiwan; Waist Circumference; Weight Loss | 2016 |
Green Tea, Intermittent Sprinting Exercise, and Fat Oxidation.
Topics: Adipose Tissue; Catechin; Cross-Over Studies; Double-Blind Method; Exercise; Female; Humans; Oxidation-Reduction; Plant Extracts; Tea; Young Adult | 2015 |
The Minnesota Green Tea Trial (MGTT), a randomized controlled trial of the efficacy of green tea extract on biomarkers of breast cancer risk: study rationale, design, methods, and participant characteristics.
Topics: Antioxidants; Biomarkers; Breast; Breast Neoplasms; Catechin; Catechol O-Methyltransferase; Double-Blind Method; Estrogens; F2-Isoprostanes; Female; Genotype; Gonadal Steroid Hormones; Humans; Insulin-Like Growth Factor I; Mammography; Middle Aged; Minnesota; Oxidative Stress; Risk Factors; Tea | 2015 |
Polyphenon E, non-futile at neuroprotection in multiple sclerosis but unpredictably hepatotoxic: Phase I single group and phase II randomized placebo-controlled studies.
Topics: Adult; Catechin; Chemical and Drug Induced Liver Injury; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Neuroprotective Agents; Plant Extracts; Treatment Outcome | 2015 |
Phase Ib Randomized, Double-Blinded, Placebo-Controlled, Dose Escalation Study of Polyphenon E in Patients with Barrett's Esophagus.
Topics: Aged; Aged, 80 and over; Barrett Esophagus; Biopsy; Catechin; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Double-Blind Method; Esophagoscopy; Female; Humans; Male; Middle Aged; Phytotherapy | 2015 |
Tracking CNS and systemic sources of oxidative stress during the course of chronic neuroinflammation.
Topics: Animals; Antioxidants; Astrocytes; Calcium; Catechin; CD11b Antigen; Chronic Disease; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Glatiramer Acetate; Humans; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Fluorescence; Multiple Sclerosis; NADPH Oxidases; Neurons; Oxidative Stress | 2015 |
Topical lipophilic epigallocatechin-3-gallate on herpes labialis: a phase II clinical trial of AverTeaX formula.
Topics: Administration, Topical; Adult; Antioxidants; Catechin; Double-Blind Method; Female; Flavonoids; Herpes Labialis; Humans; Male; Middle Aged; Quality of Life; Recurrence; Surveys and Questionnaires; Tea; Treatment Outcome | 2015 |
Green Tea Extract and Catechol-O-Methyltransferase Genotype Modify Fasting Serum Insulin and Plasma Adiponectin Concentrations in a Randomized Controlled Trial of Overweight and Obese Postmenopausal Women.
Topics: Adiponectin; Administration, Oral; Aged; Blood Glucose; Body Mass Index; Body Weight; Caffeine; Catechin; Catechol O-Methyltransferase; Double-Blind Method; Energy Intake; Fasting; Female; Genotype; Ghrelin; Humans; Insulin; Leptin; Middle Aged; Motor Activity; Nutrition Assessment; Obesity; Overweight; Plant Extracts; Polyphenols; Postmenopause; Tea; Waist Circumference | 2016 |
Phase I study of topical epigallocatechin-3-gallate (EGCG) in patients with breast cancer receiving adjuvant radiotherapy.
Topics: Administration, Topical; Adult; Antioxidants; Breast Neoplasms; Catechin; Combined Modality Therapy; Female; Humans; Mastectomy; Middle Aged; Radiodermatitis; Radiotherapy, Adjuvant; Treatment Outcome | 2016 |
Randomized, controlled, double-blind clinical study evaluating the safety and efficacy of MD2011001 cream in mild-to-moderate atopic dermatitis of the face and neck in children, adolescents and adults.
Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents; Catechin; Child; Child, Preschool; Dermatitis, Atopic; Double-Blind Method; Emollients; Face; Female; Grape Seed Extract; Humans; Male; Neck; Proanthocyanidins; Treatment Outcome; Vitamin E; Young Adult | 2016 |
Long-Term Supplementation of Green Tea Extract Does Not Modify Adiposity or Bone Mineral Density in a Randomized Trial of Overweight and Obese Postmenopausal Women.
Topics: Adipose Tissue; Adiposity; Body Composition; Body Mass Index; Bone and Bones; Bone Density; Caffeine; Camellia sinensis; Catechin; Catechol O-Methyltransferase; Dietary Supplements; Double-Blind Method; Female; Genotype; Humans; Middle Aged; Obesity; Overweight; Plant Extracts; Postmenopause; Tea | 2016 |
The PROMESA-protocol: progression rate of multiple system atrophy under EGCG supplementation as anti-aggregation-approach.
Topics: Catechin; Disease Progression; Double-Blind Method; Humans; Multiple System Atrophy; Neuroprotective Agents; Research Design | 2016 |
Oral epigallocatechin-3-gallate for treatment of dystrophic epidermolysis bullosa: a multicentre, randomized, crossover, double-blind, placebo-controlled clinical trial.
Topics: Catechin; Cross-Over Studies; Double-Blind Method; Epidermolysis Bullosa Dystrophica; Humans; Metalloendopeptidases; Phenols; United States | 2016 |
A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR.
Topics: Adolescent; Animals; Autophagy; Biomarkers; Catechin; Child; Cysteamine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Drug Therapy, Combination; Homozygote; Humans; Interleukin-8; Lung; Mice; Mice, Knockout; Mutation; Sputum; Tumor Necrosis Factor-alpha | 2016 |
Long-Term Green Tea Supplementation Does Not Change the Human Gut Microbiota.
Topics: Adult; Body Composition; Caffeine; Catechin; Dietary Supplements; Drug Administration Schedule; Feces; Female; Gastrointestinal Microbiome; Humans; Male; Middle Aged; Tea; White People; Young Adult | 2016 |
Does supplementation with green tea extract improve acne in post-adolescent women? A randomized, double-blind, and placebo-controlled clinical trial.
Topics: Acne Vulgaris; Adult; Catechin; Double-Blind Method; Female; Humans; Middle Aged; Placebos; Plant Extracts; Tea; Treatment Outcome | 2016 |
Combined epigallocatechin-3-gallate and resveratrol supplementation for 12 wk increases mitochondrial capacity and fat oxidation, but not insulin sensitivity, in obese humans: a randomized controlled trial.
Topics: Adult; Blood Glucose; Catechin; Dietary Supplements; Double-Blind Method; Energy Metabolism; Fasting; Female; Humans; Insulin; Insulin Resistance; Intra-Abdominal Fat; Lipid Metabolism; Male; Mitochondria; Muscles; Obesity; Plant Extracts; Postprandial Period; Resveratrol; Stilbenes | 2016 |
Epigallocatechin-3-gallate ameliorates radiation-induced acute skin damage in breast cancer patients undergoing adjuvant radiotherapy.
Topics: Administration, Cutaneous; Adult; Breast; Breast Neoplasms; Catechin; Female; Humans; Mastectomy; Middle Aged; Pain; Pain Management; Prospective Studies; Radiation-Protective Agents; Radiodermatitis; Radiotherapy, Adjuvant; Treatment Outcome; Young Adult | 2016 |
Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down's syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 trial.
Topics: Adaptation, Psychological; Adult; Catechin; Cholesterol; Cognition Disorders; Cognitive Behavioral Therapy; Double-Blind Method; Down Syndrome; Female; Follow-Up Studies; Homocysteine; Humans; Inhibition, Psychological; Male; Neuroprotective Agents; Recognition, Psychology; Retrospective Studies; Spain; Treatment Outcome; Young Adult | 2016 |
The use of green tea polyphenols for treating residual albuminuria in diabetic nephropathy: A double-blind randomised clinical trial.
Topics: Aged; Albuminuria; Apoptosis; Catechin; Cells, Cultured; Diabetic Nephropathies; Double-Blind Method; Female; Humans; Male; Middle Aged; Pisum sativum; Podocytes; Polyphenols | 2016 |
Green tea extract and catechol-O-methyltransferase genotype modify the post-prandial serum insulin response in a randomised trial of overweight and obese post-menopausal women.
Topics: Adiponectin; Aged; Antioxidants; Body Mass Index; Catechin; Catechol O-Methyltransferase; Dietary Supplements; Double-Blind Method; Female; Genotype; Ghrelin; Humans; Insulin; Leptin; Middle Aged; Obesity; Overweight; Plant Extracts; Postmenopause; Postprandial Period; Surveys and Questionnaires; Tea | 2017 |
Effects of green tea catechin extract on serum lipids in postmenopausal women: a randomized, placebo-controlled clinical trial.
Topics: Antioxidants; Biomarkers; Body Mass Index; Catechin; Catechol O-Methyltransferase; Cholesterol, HDL; Cholesterol, LDL; Dietary Supplements; Double-Blind Method; Female; Humans; Lipids; Middle Aged; Obesity; Plant Extracts; Postmenopause; Tea; Treatment Outcome; Triglycerides | 2016 |
Phase 2 trial of daily, oral epigallocatechin gallate in patients with light-chain amyloidosis.
Topics: Adult; Aged; Aged, 80 and over; Amyloidosis; Antioxidants; Catechin; Female; Humans; Immunoglobulin Light-chain Amyloidosis; Male; Middle Aged; Oxidative Stress; Reactive Oxygen Species; Tea; Treatment Outcome | 2017 |
Dietary epigallocatechin 3-gallate supplement improves maternal and neonatal treatment outcome of gestational diabetes mellitus: a double-blind randomised controlled trial.
Topics: Adult; Anthropometry; Blood Glucose; Catechin; Diabetes, Gestational; Dietary Supplements; Double-Blind Method; Female; Fetal Macrosomia; Humans; Hypoglycemia; Infant; Infant, Low Birth Weight; Insulin; Nutrition Assessment; Pregnancy; Prenatal Exposure Delayed Effects; Respiratory Distress Syndrome, Newborn; Treatment Outcome | 2017 |
Effect of epigallocatechin-3-gallate, major ingredient of green tea, on the pharmacokinetics of rosuvastatin in healthy volunteers.
Topics: Adult; Area Under Curve; Catechin; Female; Herb-Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Rosuvastatin Calcium; Tea; Young Adult | 2017 |
Tea-induced improvement of endothelial function in humans: No role for epigallocatechin gallate (EGCG).
Topics: Adult; Analysis of Variance; Arm; Brachial Artery; Catechin; Cross-Over Studies; Endothelium, Vascular; Humans; Male; Pilot Projects; Plant Extracts; Prospective Studies; Tea; Vasodilation | 2017 |
Gut microbiota composition in relation to the metabolic response to 12-week combined polyphenol supplementation in overweight men and women.
Topics: Absorptiometry, Photon; Adult; Bacteroidetes; Catechin; Double-Blind Method; Energy Metabolism; Faecalibacterium prausnitzii; Feces; Female; Gastrointestinal Microbiome; Humans; Male; Muscle, Skeletal; Overweight; Polyphenols; Resveratrol; Stilbenes; Treatment Outcome | 2017 |
Epigallocatechin gallate enhances treatment efficacy of oral nifedipine against pregnancy-induced severe pre-eclampsia: A double-blind, randomized and placebo-controlled clinical study.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; Catechin; Double-Blind Method; Female; Humans; Nifedipine; Pre-Eclampsia; Pregnancy; Treatment Outcome | 2018 |
Reduced Stress and Improved Sleep Quality Caused by Green Tea Are Associated with a Reduced Caffeine Content.
Topics: Adult; alpha-Amylases; Caffeine; Catechin; Cross-Over Studies; Double-Blind Method; Female; Glutamates; Humans; Male; Middle Aged; Sleep; Stress, Psychological; Tea | 2017 |
An intervention study on the effect of matcha tea, in drink and snack bar formats, on mood and cognitive performance.
Topics: Adult; Affect; Attention; Caffeine; Camellia sinensis; Catechin; Cognition; Female; Glutamates; Humans; Male; Memory; Netherlands; Psychomotor Performance; Single-Blind Method; Snacks; Task Performance and Analysis; Tea; Time Factors; Young Adult | 2017 |
A Randomized Controlled Trial of Green Tea Extract Supplementation and Mammographic Density in Postmenopausal Women at Increased Risk of Breast Cancer.
Topics: Aged; Anticarcinogenic Agents; Antioxidants; Body Mass Index; Breast; Breast Density; Breast Neoplasms; Catechin; Catechol O-Methyltransferase; Dietary Supplements; Double-Blind Method; Female; Genotype; Humans; Mammography; Middle Aged; Plant Extracts; Postmenopause; Tamoxifen; Tea | 2017 |
Anti-platelet effects of epigallocatechin-3-gallate in addition to the concomitant aspirin, clopidogrel or ticagrelor treatment.
Topics: Adult; Aged; Aspirin; Blood Platelets; Catechin; Clopidogrel; Coronary Stenosis; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Republic of Korea; Ticagrelor; Ticlopidine | 2018 |
Lack of pharmacokinetic interaction between fluvastatin and green tea in healthy volunteers.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Cross-Over Studies; Cytochrome P-450 CYP2C9; Diclofenac; Fatty Acids, Monounsaturated; Female; Fluvastatin; Food-Drug Interactions; Healthy Volunteers; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Tea; Young Adult | 2018 |
Population nutrikinetics of green tea extract.
Topics: Adult; Catechin; Female; Humans; Male; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Pharmacogenomic Testing; Plant Extracts; Polymorphism, Genetic; Polyphenols; Tea | 2018 |
Role of (-)-epigallocatechin gallate in the pharmacokinetic interaction between nadolol and green tea in healthy volunteers.
Topics: Adrenergic beta-Antagonists; Adult; Antioxidants; Blood Proteins; Camellia sinensis; Catechin; Cross-Over Studies; Drug Interactions; Female; Healthy Volunteers; HEK293 Cells; Humans; Male; Middle Aged; Nadolol; Organic Anion Transporters; Plant Extracts; Protein Binding; Young Adult | 2018 |
A Randomized, Placebo-Controlled Study on the Safety and Efficacy of Daily Ingestion of Green Tea (
Topics: Accommodation, Ocular; Adult; Anthocyanins; Asthenopia; Blood Pressure; Catechin; Catechols; Diet; Double-Blind Method; Female; Flavonols; Humans; Male; Middle Aged; Plant Extracts; Plant Leaves; Surveys and Questionnaires; Tea; Treatment Outcome; Visual Analog Scale; Young Adult | 2018 |
The effects of polyphenol supplementation on adipose tissue morphology and gene expression in overweight and obese humans.
Topics: Adipose Tissue; Adult; Catechin; Dietary Supplements; Double-Blind Method; Female; Gene Expression; Humans; Male; Obesity; Overweight; Polyphenols; Resveratrol | 2018 |
Acute Epigallocatechin 3 Gallate (EGCG) Supplementation Delays Gastric Emptying in Healthy Women: A Randomized, Double-Blind, Placebo-Controlled Crossover Study.
Topics: Adiponectin; Adiposity; Appetite; Blood Glucose; Body Mass Index; Brazil; Catechin; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Female; Gastric Emptying; Humans; Hunger; Insulin; Leptin; Satiation; Young Adult | 2018 |
Stress-Reducing Function of Matcha Green Tea in Animal Experiments and Clinical Trials.
Topics: Adrenal Glands; Animals; Anti-Anxiety Agents; Arginine; Caffeine; Catechin; Female; Glutamates; Healthy Volunteers; Humans; Hypertrophy; Male; Mice; Stress, Psychological; Tea; Territoriality; Young Adult | 2018 |
Effect of Epigallo-Catechin-3-Gallate on Lipid Metabolism Related Gene Expression and Yolk Fatty Acid Profiles of Laying Hens Exposed to Vanadium.
Topics: Animals; Catechin; Chickens; Dietary Supplements; Dose-Response Relationship, Drug; Egg Yolk; Fatty Acid Synthases; Fatty Acids; Gene Expression Profiling; Lipid Metabolism; PPAR gamma; Sterol Regulatory Element Binding Protein 1; Vanadium | 2019 |
The effect of Epigallocatechin-3-gallate on small intestinal morphology, antioxidant capacity and anti-inflammatory effect in heat-stressed broilers.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Catechin; Chickens; Heat Stress Disorders; Intestinal Mucosa; Intestine, Small; Male; Poultry Diseases | 2019 |
A Double-Blind, Randomized Trial Shows the Role of Zonal Priming and Direct Topical Application of Epigallocatechin-3-Gallate in the Modulation of Cutaneous Scarring in Human Skin.
Topics: Administration, Cutaneous; Adult; Catechin; Cicatrix; Double-Blind Method; Female; Humans; Male; Skin; Treatment Outcome; Wounds and Injuries; Young Adult | 2019 |
Global testing of shifts in metabolic phenotype.
Topics: Catechin; Dietary Supplements; Double-Blind Method; Humans; Metabolomics; Obesity; Phenotype; Resveratrol; Weight Loss | 2018 |
A prospective, three-arm, randomized trial of EGCG for preventing radiation-induced esophagitis in lung cancer patients receiving radiotherapy.
Topics: Acute Disease; Aged; Carcinoma, Non-Small-Cell Lung; Catechin; Chemoradiotherapy; Esophagitis; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Prospective Studies; Radiation Injuries; Radiation-Protective Agents; Radiotherapy Dosage | 2019 |
A phase 1, randomized double-blind, placebo controlled trial to evaluate safety and efficacy of epigallocatechin-3-gallate and cognitive training in adults with Fragile X syndrome.
Topics: Adult; Animals; Catechin; Cognition Disorders; Disease Models, Animal; Double-Blind Method; Female; Fragile X Syndrome; Humans; Male; Mice; Mice, Knockout; Middle Aged; Neuroprotective Agents; Treatment Outcome; Young Adult | 2020 |
Effect of epigallocatechin gallate on the body composition and lipid profile of down syndrome individuals: Implications for clinical management.
Topics: Adolescent; Adult; Antioxidants; Body Composition; Body Mass Index; Catechin; Cohort Studies; Double-Blind Method; Down Syndrome; Electric Impedance; Female; Humans; Lipids; Male; Sex Factors; Young Adult | 2020 |
Safety and efficacy of epigallocatechin gallate in multiple system atrophy (PROMESA): a randomised, double-blind, placebo-controlled trial.
Topics: Aged; Catechin; Disease Progression; Double-Blind Method; Female; Germany; Humans; Male; Middle Aged; Multiple System Atrophy; Neuroprotective Agents; Treatment Outcome | 2019 |
Effects of timing of acute catechin-rich green tea ingestion on postprandial glucose metabolism in healthy men.
Topics: Adult; Blood Glucose; Catechin; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Fasting; Fatty Acids, Nonesterified; Gastric Inhibitory Polypeptide; Glucagon-Like Peptide 1; Humans; Insulin; Male; Meals; Placebos; Postprandial Period; Tea; Time Factors; Triglycerides; Young Adult | 2019 |
Addition of Epigallocatechin Gallate 400 mg to Sofosbuvir 400 mg + Daclatisvir 60 mg With or Without Ribavirin in Treatment of Patients with Chronic Hepatitis C Improves the Safety Profile: A Pilot Study.
Topics: Adult; Catechin; Daclizumab; Drug Administration Schedule; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Male; Middle Aged; Pilot Projects; Random Allocation; Ribavirin; Sofosbuvir; Standard of Care; Sustained Virologic Response; Tablets; Treatment Outcome; Viral Load | 2019 |
Epigallocatechin-3-gallate mouthwash protects mucosa from radiation-induced mucositis in head and neck cancer patients: a prospective, non-randomised, phase 1 trial.
Topics: Adult; Aged; Catechin; Chemoradiotherapy; Head and Neck Neoplasms; Humans; Maximum Tolerated Dose; Middle Aged; Mouth Mucosa; Mouthwashes; Mucositis; Prospective Studies; Radiation Injuries; Young Adult | 2020 |
Phase II Trial of Epigallocatechin-3-Gallate in Acute Radiation-Induced Esophagitis for Esophagus Cancer.
Topics: Adult; Aged; Catechin; Chemoradiotherapy; China; Esophageal Neoplasms; Esophagitis; Female; Humans; Male; Middle Aged; Prospective Studies; Radiation Injuries | 2020 |
The Impact of Coconut Oil and Epigallocatechin Gallate on the Levels of IL-6, Anxiety and Disability in Multiple Sclerosis Patients.
Topics: Anxiety; Biomarkers; Body Mass Index; Catechin; Coconut Oil; Diet, Mediterranean; Dietary Supplements; Disability Evaluation; Emotions; Female; Humans; Interleukin-6; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Pilot Projects; Prospective Studies; Recovery of Function; Spain; Time Factors; Treatment Outcome | 2020 |
Effects of Timing of Acute and Consecutive Catechin Ingestion on Postprandial Glucose Metabolism in Mice and Humans.
Topics: Adult; Animals; Blood Glucose; Carbohydrate Metabolism; Catechin; Double-Blind Method; Drinking; Female; Healthy Volunteers; Humans; Male; Mice; Models, Animal; Placebos; Postprandial Period; Tea; Time Factors; Young Adult | 2020 |
Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Amylose; Anaerobiosis; Animals; Anti-Bacterial Agents; Anura; Arginase; Arthritis, Rheumatoid; Asthma; Atmosphere; B-Lymphocytes; Basic Helix-Loop-Helix Transcription Factors; Bioelectric Energy Sources; Biofilms; Biofuels; Biomarkers; Biopolymers; Bioreactors; Brain; Brain Injuries, Traumatic; Breast Neoplasms; Calibration; Carbon Tetrachloride; Caspase 3; Catalysis; Catechin; Cations; Cattle; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Body; Cell Line, Tumor; Cell Plasticity; Chemical and Drug Induced Liver Injury; Chemistry Techniques, Synthetic; China; Chitosan; Chloride Channels; Chromatography, High Pressure Liquid; Chromosome Mapping; Cognition; Cognitive Dysfunction; Cohort Studies; Colitis, Ulcerative; Colloids; Coloring Agents; Congresses as Topic; Correlation of Data; Crystallization; Cyanoacrylates; Cyclohexane Monoterpenes; Cyprinidae; Cytochrome P-450 CYP1A1; Death, Sudden; Dent Disease; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Disease Progression; Disease Resistance; Disulfides; Drug Monitoring; Drug Stability; Ecotoxicology; Electricity; Electrodes; Endocytosis; Environmental Exposure; Environmental Monitoring; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Esophageal and Gastric Varices; Esters; Fagopyrum; Female; Ferrosoferric Oxide; Flame Retardants; Flavobacteriaceae; Flow Cytometry; Follow-Up Studies; Formoterol Fumarate; Fusarium; Garlic; Gastrointestinal Hemorrhage; Gene Expression; Genes, Plant; Genetic Markers; Glial Fibrillary Acidic Protein; Gliosis; Global Health; Glutathione Transferase; Glycine max; Gum Arabic; Hemostasis, Endoscopic; Hepatocytes; Hippocampus; Humans; Hydrogen-Ion Concentration; Illinois; Immunoglobulin G; Indoleamine-Pyrrole 2,3,-Dioxygenase; Infant, Newborn; Infant, Small for Gestational Age; Injections, Intraperitoneal; Interleukin-4; Iowa; Iron; Ki-67 Antigen; Kidney; Kinetics; Kynurenine; Lakes; Levofloxacin; Lipid Peroxidation; Lipids; Liver; Liver Cirrhosis, Experimental; Magnetic Fields; Magnetic Iron Oxide Nanoparticles; Male; Manure; Maze Learning; Memory, Short-Term; Metal Nanoparticles; Metals, Heavy; Methane; Mice; Mice, Inbred C57BL; Mice, Knockout; Michigan; Microalgae; Microbial Consortia; Mitochondria; Models, Animal; Models, Chemical; Models, Neurological; Molecular Structure; Molecular Weight; Mutation; Myeloid-Derived Suppressor Cells; NADPH Oxidase 2; Neoplasm Recurrence, Local; Neurites; Neurons; Neuroprotective Agents; NF-kappa B; NIH 3T3 Cells; Nitric Oxide Synthase Type II; Nitrogen; Ohio; Ointments; Ontario; Organelle Biogenesis; Organophosphates; Organophosphorus Compounds; Oxidative Stress; Palladium; Particle Size; Pectins; Phenotype; Phytotherapy; Piperidines; Placenta; Plant Diseases; Plant Extracts; Polymers; Polymorphism, Genetic; Polyphenols; Powders; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Protein Kinase Inhibitors; Protein Structure, Secondary; Proteins; Pyridines; Pyrimidines; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Receptors, Chemokine; Receptors, Formyl Peptide; Receptors, Lipoxin; Recovery of Function; Recurrence; Reference Standards; Reference Values; Reproducibility of Results; Respiratory Function Tests; Retrospective Studies; Risk; Sensitivity and Specificity; Sewage; Signal Transduction; Sodium Glutamate; Soil; Solanum tuberosum; Solubility; Solutions; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spermatozoa; STAT3 Transcription Factor; Sulfamethoxazole; Tea; Temperature; Thermodynamics; Thrombin; Treatment Outcome; Triazoles; United States; Viscosity; Waste Disposal, Fluid; Wastewater; Water; Water Pollutants, Chemical; Water Purification; White Matter; Wisconsin; X-Ray Diffraction; Zea mays | 2013 |
Efficacy of green tea and its extract, epigallocatechin-3-gallate, in the reduction of cariogenic microbiota in children: a randomized clinical trial.
Topics: Catechin; Child; Child, Preschool; Humans; Lactobacillaceae; Microbiota; Mouth; Mouthwashes; Plant Extracts; Streptococcus mutans; Tea | 2020 |
The phytochemical epigallocatechin gallate prolongs the lifespan by improving lipid metabolism, reducing inflammation and oxidative stress in high-fat diet-fed obese rats.
Topics: Animals; Catechin; Diet, High-Fat; Humans; Inflammation; Lipid Metabolism; Longevity; Male; Obesity; Oxidative Stress; Phytochemicals; Rats; Rats, Wistar | 2020 |
Assessing the analgesic efficacy of oral epigallocatechin-3-gallate on epidural catheter analgesia in patients after surgical stabilisation of multiple rib fractures: a prospective double-blind, placebo-controlled clinical trial.
Topics: Adult; Aged; Analgesia, Epidural; Analgesics; Catechin; Double-Blind Method; Female; Humans; Male; Middle Aged; Oxygen; Pain; Pain Measurement; Prospective Studies; Respiratory Rate; Rib Fractures; Spirometry; Young Adult | 2020 |
Acute Epigallocatechin-3-Gallate Supplementation Alters Postprandial Lipids after a Fast-Food Meal in Healthy Young Women: A Randomized, Double-Blind, Placebo-Controlled Crossover Study.
Topics: Adult; Blood Glucose; Catechin; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Fast Foods; Fatty Acid Synthases; Fatty Acids; Female; Healthy Volunteers; Humans; Insulin; Lipid Metabolism; Lipoproteins, HDL; Meals; Postprandial Period; Triglycerides; Young Adult | 2020 |
Epigallocatechin gallate decreases plasma triglyceride, blood pressure, and serum kisspeptin in obese human subjects.
Topics: Adipocytes, Brown; Adipocytes, White; Adiponectin; Adult; Blood Glucose; Blood Pressure; Catechin; Humans; Kidney; Kisspeptins; Leptin; Lipolysis; Liver; Middle Aged; Obesity; RNA, Messenger; Triglycerides; Uncoupling Protein 1 | 2021 |
Impact of Green Tea Catechin Ingestion on the Pharmacokinetics of Lisinopril in Healthy Volunteers.
Topics: Administration, Oral; Adult; Catechin; Cross-Over Studies; Fasting; Female; Food-Drug Interactions; Healthy Volunteers; Humans; Intestinal Absorption; Lisinopril; Male; Tea; Young Adult | 2021 |
Possible Reduction of Cardiac Risk after Supplementation with Epigallocatechin Gallate and Increase of Ketone Bodies in the Blood in Patients with Multiple Sclerosis. A Pilot Study.
Topics: 3-Hydroxybutyric Acid; Adult; Analysis of Variance; Anthropometry; Aryldialkylphosphatase; Body Mass Index; C-Reactive Protein; Cardiotonic Agents; Cardiovascular Diseases; Catechin; Dietary Supplements; Female; Heart Disease Risk Factors; Humans; Ketone Bodies; Male; Middle Aged; Multiple Sclerosis; Pilot Projects; Serum Albumin; Treatment Outcome; Waist-Height Ratio | 2020 |
Efficacy of (-)-epigallocatechin gallate delivered by a new-type scaler tip during scaling and root planing on chronic periodontitis: a split-mouth, randomized clinical trial.
Topics: Catechin; Chronic Periodontitis; Dental Scaling; Humans; Periodontal Attachment Loss; Root Planing; Treatment Outcome | 2021 |
Epigallocatechin Gallate in Progressive MS: A Randomized, Placebo-Controlled Trial.
Topics: Administration, Oral; Adult; Atrophy; Brain; Catechin; Disease Progression; Double-Blind Method; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Outcome Assessment, Health Care; Random Allocation | 2021 |
Novel combined single dose anti-hepatitis C therapy: a pilot study.
Topics: Adult; Antiviral Agents; Catechin; Female; Genotype; Hepatitis C; Humans; Male; Middle Aged; Pilot Projects; Ribavirin; Sofosbuvir | 2021 |
Epigallocatechin Gallate in Relapsing-Remitting Multiple Sclerosis: A Randomized, Placebo-Controlled Trial.
Topics: Adult; Brain; Catechin; Double-Blind Method; Glatiramer Acetate; Humans; Magnetic Resonance Imaging; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Prospective Studies; Young Adult | 2021 |
Topical epigallocatechin-3-gallate in the treatment of vitiligo.
Topics: Administration, Topical; Adult; Catechin; Dermatologic Agents; Female; Humans; Male; Middle Aged; Prospective Studies; Treatment Outcome; Vitiligo | 2021 |
Effects of epigallocatechin-3-gallate of
Topics: Antioxidants; Biomarkers; Blood Pressure; Camellia sinensis; Catechin; Diabetes Mellitus, Type 2; Flour; Humans; Lipids; Plant Leaves; Triticum | 2020 |
The combined effect of green tea and α-glucosyl hesperidin in preventing obesity: a randomized placebo-controlled clinical trial.
Topics: Adult; Body Mass Index; Catechin; Female; Glucosides; Hesperidin; Humans; Male; Middle Aged; Obesity; Placebos; Tea | 2021 |
Possible Role of Butyrylcholinesterase in Fat Loss and Decreases in Inflammatory Levels in Patients with Multiple Sclerosis after Treatment with Epigallocatechin Gallate and Coconut Oil: A Pilot Study.
Topics: Adipose Tissue; Adult; Antioxidants; Butyrylcholinesterase; Catechin; Coconut Oil; Dietary Supplements; Female; Humans; Inflammation; Lipid Metabolism; Male; Middle Aged; Multiple Sclerosis; Obesity; Pilot Projects; Weight Loss | 2021 |
The effect of (-)-epigallocatechin gallate as an adjunct to non-surgical periodontal treatment: a randomized clinical trial.
Topics: Catechin; Chronic Periodontitis; Humans; Root Planing; Water | 2022 |
Efficacy of Epigallocatechin-3-Gallate in Preventing Dermatitis in Patients With Breast Cancer Receiving Postoperative Radiotherapy: A Double-Blind, Placebo-Controlled, Phase 2 Randomized Clinical Trial.
Topics: Breast Neoplasms; Catechin; Female; Humans; Middle Aged; Radiodermatitis; Treatment Outcome | 2022 |
Green tea catechin EGCG could prevent obesity-related precocious puberty through NKB/NK3R signaling pathway.
Topics: Animals; Camellia sinensis; Catechin; Female; Humans; Neurokinin B; Obesity; Puberty, Precocious; Rats; Retrospective Studies; Signal Transduction | 2022 |
Safety and preliminary efficacy on cognitive performance and adaptive functionality of epigallocatechin gallate (EGCG) in children with Down syndrome. A randomized phase Ib clinical trial (PERSEUS study).
Topics: Catechin; Child; Cognition; Dietary Supplements; Double-Blind Method; Down Syndrome; Female; Humans; Male | 2022 |
Assessing the Hepatic Safety of Epigallocatechin Gallate (EGCG) in Reproductive-Aged Women.
Topics: Adult; Catechin; Clomiphene; Female; Folic Acid; Humans; Infertility; Leiomyoma; Letrozole; Liver; Prospective Studies; Tea | 2023 |
The polyphenol epigallocatechin gallate lowers circulating catecholamine concentrations and alters lipid metabolism during graded exercise in man: a randomized cross-over study.
Topics: Catechin; Cross-Over Studies; Exercise; Glucose; Humans; Lactic Acid; Lipid Metabolism; Lipids; Male; Metanephrine; Polyphenols; Single-Blind Method | 2023 |
Efficacy and safety of epigallocatechin-3-gallate in treatment acute severe dermatitis in patients with cancer receiving radiotherapy: a phase I clinical trial.
Topics: Acute Disease; Catechin; Dermatitis; Humans; Neoplasms; Radiodermatitis | 2023 |
Biomodification of eroded and abraded dentin with epigallocatechin-3-gallate (EGCG).
Topics: Adhesives; Animals; Catechin; Cattle; Dental Bonding; Dentin; Dentin-Bonding Agents; Materials Testing; Resin Cements; Tensile Strength | 2023 |
4488 other study(ies) available for catechin and epigallocatechin gallate
| Article | Year |
|---|---|
Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Boronic Acids; Bortezomib; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Drug Resistance, Neoplasm; Humans; Indoles; Melanoma; Mice; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Proteasome Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Pyrroles | 2007 |
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.
Topics: Flavonoids; Free Radical Scavengers; Models, Biological; Quantitative Structure-Activity Relationship; Quantum Theory; Software; Thermodynamics | 2010 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
New diarylheptanoids from the stems of Carpinus cordata.
Topics: Antioxidants; Betulaceae; Biphenyl Compounds; Free Radical Scavengers; Inhibitory Concentration 50; Korea; Models, Chemical; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Picrates; Plant Stems; Polycyclic Aromatic Hydrocarbons; Spectroscopy, Fourier Transform Infrared; Stereoisomerism | 2002 |
Expanding the ChemGPS chemical space with natural products.
Topics: Biological Products; Combinatorial Chemistry Techniques; Computer Graphics; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship | 2005 |
Efficiency of foam fractionation for the enrichment of nonpolar compounds from aqueous extracts of plant materials.
Topics: Carotenoids; Chemical Fractionation; Chromatography, High Pressure Liquid; Citrus; Curcuma; Curcumin; Cyclohexenes; Daucus carota; Flavanones; Hesperidin; Molecular Structure; Plant Extracts; Tea; Terpenes; Water | 2005 |
Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Alcohol Oxidoreductases; Animals; Antimalarials; Catechin; Cells, Cultured; Chloroquine; Drug Resistance; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Fatty Acids; Flavones; Flavonoids; Humans; Hydro-Lyases; Kinetics; Luteolin; Phenols; Plasmodium falciparum; Polyphenols; Structure-Activity Relationship | 2006 |
A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.
Topics: Amyloid beta-Peptides; Benzothiazoles; Coloring Agents; Congo Red; Fluorescent Dyes; Indoles; Spectrometry, Fluorescence; Thiazoles | 2009 |
Carboxymethylated-kappa-casein: a convenient tool for the identification of polyphenolic inhibitors of amyloid fibril formation.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Caseins; Flavonoids; Humans; Methylation; Milk; Structure-Activity Relationship | 2010 |
Synthesis and antimicrobial activities of 3-O-alkyl analogues of (+)-catechin: improvement of stability and proposed action mechanism.
Topics: Anti-Infective Agents; Bacteria; Camellia sinensis; Catechin; Drug Design; Drug Stability; Fungi; Humans; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Molecular Structure; Tea | 2010 |
Comparative study on antioxidant capacity of flavonoids and their inhibitory effects on oleic acid-induced hepatic steatosis in vitro.
Topics: Antioxidants; Cell Line; Fatty Liver; Flavonoids; Humans; In Vitro Techniques; Oleic Acid; Reactive Oxygen Species; Triglycerides | 2011 |
Tea catechins and flavonoids from the leaves of Camellia sinensis inhibit yeast alcohol dehydrogenase.
Topics: Alcohol Dehydrogenase; Camellia sinensis; Catechin; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Plant Leaves; Saccharomyces cerevisiae; Tea | 2012 |
The synthesis, antimalarial activity and CoMFA analysis of novel aminoalkylated quercetin analogs.
Topics: Antimalarials; Humans; Malaria; Models, Molecular; Molecular Structure; Plasmodium falciparum; Quantitative Structure-Activity Relationship; Quercetin; Stereoisomerism | 2015 |
Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
Topics: Cell Differentiation; Flavonoids; Humans; Mesenchymal Stem Cells; Molecular Structure; Osteogenesis; Signal Transduction; Structure-Activity Relationship | 2015 |
Flavones Inhibit the Activity of AKR1B10, a Promising Therapeutic Target for Cancer Treatment.
Topics: Aldehyde Reductase; Aldo-Keto Reductases; Apigenin; Daunorubicin; Enzyme Inhibitors; Flavones; Flavonoids; HCT116 Cells; Humans; Luteolin; Molecular Conformation; Molecular Structure; Neoplasms | 2015 |
Discovery of hyaluronidase inhibitors from natural products and their mechanistic characterization under DMSO-perturbed assay conditions.
Topics: Animals; Binding Sites; Catechin; Cattle; Dimethyl Sulfoxide; Drug Discovery; Enzyme Assays; Enzyme Inhibitors; Glycyrrhizic Acid; Hyaluronoglucosaminidase; Male; Octoxynol; Panax; Plant Extracts; Prunus domestica; Saponins | 2017 |
Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors.
Topics: Antiviral Agents; Crystallography, X-Ray; Drug Evaluation, Preclinical; Endonucleases; Enzyme Assays; Enzyme Inhibitors; Flavonoids; Influenza A virus; Microbial Sensitivity Tests; Molecular Structure; Protein Binding; Protein Domains; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Viral Proteins | 2020 |
A role of flavonoids in cytochrome c-cardiolipin interactions.
Topics: Cardiolipins; Cytochromes c; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Humans; Molecular Structure; Oxidation-Reduction; Structure-Activity Relationship | 2021 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
[The inhibitory effects of catechin derivatives on the activities of human immunodeficiency virus reverse transcriptase and DNA polymerases].
Topics: Animals; Antiviral Agents; Catechin; DNA-Directed DNA Polymerase; Enterovirus B, Human; Flavonoids; HIV Reverse Transcriptase; HIV-1; Humans; Plant Extracts; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Simplexvirus; Tea; Vero Cells | 1992 |
[Quantitative estimation of active principles polyphenols in green tea].
Topics: Catechin; Flavonoids; Tea | 1992 |
Monoamine metabolites, iron induced seizures, and the anticonvulsant effect of tannins.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anticonvulsants; Biogenic Monoamines; Brain; Catechin; Chlorides; Epilepsy; Ferric Compounds; Flavonoids; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Rats; Rats, Inbred Strains | 1992 |
[Protective activity of tea and catechins against Bordetella pertussis].
Topics: Animals; Bacterial Adhesion; Biflavonoids; Bordetella pertussis; Catechin; Cricetinae; Cricetulus; Depression, Chemical; Female; Gallic Acid; HeLa Cells; Humans; Microbial Sensitivity Tests; Ovary; Tea | 1992 |
[Antimicrobial and microbicidal activities of tea and catechins against Mycoplasma].
Topics: Biflavonoids; Catechin; Gallic Acid; Microbial Sensitivity Tests; Mycoplasma; Tea | 1992 |
(-)-Epigallocatechin-3-gallate in Camellia sinensis leaves from Himalayan region of Sikkim: inhibitory effects against biochemical events and tumor initiation in Sencar mouse skin.
Topics: Administration, Cutaneous; Animals; Antimutagenic Agents; Catechin; DNA; Enzyme Induction; Female; Masoprocol; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Sikkim; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate; Tritium | 1992 |
Mitogenic activity of (-)epigallocatechin gallate on B-cells and investigation of its structure-function relationship.
Topics: Adjuvants, Immunologic; Animals; B-Lymphocytes; Catechin; Lymphocyte Activation; Male; Mice; Mice, Inbred C3H; Mitogens; Structure-Activity Relationship; T-Lymphocytes | 1992 |
Lens opacification and H2O2 elevation induced by a tumor promoter.
Topics: Animals; Antineoplastic Agents; Cataract; Catechin; Cattle; Diterpenes; Glucose; Glucose Oxidase; Hydrogen Peroxide; Lens, Crystalline; Tetradecanoylphorbol Acetate | 1992 |
Stimulation of human monocyte and polymorphonuclear cell iodination and interleukin-1 production by epigallocatechin gallate.
Topics: Adjuvants, Immunologic; Animals; Antimutagenic Agents; Catechin; Cells, Cultured; Endotoxins; Humans; Interleukin-1; Iodine; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Monocytes; Neutrophils; Stimulation, Chemical | 1992 |
Suppression of genotoxicity of carcinogens by (-)-epigallocatechin gallate.
Topics: Animals; Antimutagenic Agents; Carcinogenicity Tests; Catechin; DNA Damage; Flavonoids; Mice; Phenols; Polymers; Tea | 1992 |
Inhibition of tobacco-specific nitrosamine-induced lung tumorigenesis in A/J mice by green tea and its major polyphenol as antioxidants.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Caffeine; Carcinogens; Catechin; Deoxyguanosine; DNA; Female; Guanine; Liver; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Tea | 1992 |
Tea catechins decrease micellar solubility and intestinal absorption of cholesterol in rats.
Topics: Animals; Bile Acids and Salts; Catechin; Cholesterol; Flavonoids; Intestinal Absorption; Male; Micelles; Rats; Rats, Inbred Strains; Solubility; Tea; Triglycerides | 1992 |
Inhibition of rotavirus and enterovirus infections by tea extracts.
Topics: Animals; Antiviral Agents; Biflavonoids; Catechin; Cell Line; Enterovirus; Rotavirus; Tea; Virus Replication | 1991 |
Radioprotective effects of (-)-epigallocatechin 3-O-gallate (green-tea tannin) in mice.
Topics: Animals; Antimutagenic Agents; Catechin; Cell Division; Cells, Cultured; HeLa Cells; Humans; Lipid Peroxides; Liver; Male; Mice; Mice, Inbred ICR; Radiation-Protective Agents; Tannins | 1992 |
Inhibition of azoxymethane-induced colon carcinogenesis in rat by green tea polyphenol fraction.
Topics: Animals; Azoxymethane; Body Weight; Catechin; Colonic Neoplasms; Flavonoids; Male; Phenols; Plant Extracts; Polymers; Rats; Rats, Inbred F344; Tea; Time Factors | 1991 |
[Quantitative analysis of (-)-epigallocatechin gallate in tea leaves by high-performance liquid chromatography].
Topics: Catechin; Chromatography, High Pressure Liquid; Tea | 1991 |
Inhibitory effect of (-)-epigallocatechin gallate on carcinogenesis with N-ethyl-N'-nitro-N-nitrosoguanidine in mouse duodenum.
Topics: Animals; Carcinogens; Catechin; Duodenal Neoplasms; Male; Methylnitronitrosoguanidine; Mice; Mice, Inbred C57BL; Molecular Structure | 1989 |
[Inhibitory effect of green tea extract on promotion and related action of TPA].
Topics: Animals; Antioxidants; Catechin; Cell Transformation, Neoplastic; Edema; Female; Mice; Mice, Inbred BALB C; Ornithine Decarboxylase; Sister Chromatid Exchange; Tea; Tetradecanoylphorbol Acetate | 1989 |
The effect of crude drugs on experimental hypercholesteremia: mode of action of (-)-epigallocatechin gallate in tea leaves.
Topics: Animals; Anticholesteremic Agents; Catechin; Hypercholesterolemia; Male; Rats; Rats, Inbred Strains; Tea | 1988 |
Effects of catechins on the mouse tumor cell adhesion to fibronectin.
Topics: Animals; Binding Sites; Catechin; Cell Adhesion; Fibronectins; Lung Neoplasms; Melanoma, Experimental; Mice; Tumor Cells, Cultured | 1995 |
Inhibitory effects of (-)-epigallocatechin gallate on spontaneous hepatoma in C3H/HeNCrj mice and human hepatoma-derived PLC/PRF/5 cells.
Topics: alpha-Fetoproteins; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Carcinoma, Hepatocellular; Catechin; Cell Division; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Tumor Cells, Cultured | 1994 |
Absorption of (-)-epigallocatechin gallate into the circulation system of rats.
Topics: Absorption; Administration, Oral; Animals; Catechin; Male; Rats; Rats, Wistar; Tea; Trimethylsilyl Compounds | 1995 |
Effects of three dietary phytochemicals from tea, rosemary and turmeric on inflammation-induced nitrite production.
Topics: Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Catechin; Cell Survival; Curcumin; Inflammation; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Nitrites; Phenanthrenes; Recombinant Proteins; Spices; Tea; Tumor Necrosis Factor-alpha | 1995 |
Selective inhibition of steroid 5 alpha-reductase isozymes by tea epicatechin-3-gallate and epigallocatechin-3-gallate.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Catechin; Cell Line; Enzyme Inhibitors; Genitalia, Male; Humans; Isoenzymes; Kinetics; Male; Microsomes; Microsomes, Liver; Prostate; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Seminal Vesicles; Structure-Activity Relationship; Tea; Transfection | 1995 |
Growth inhibition and regression of human prostate and breast tumors in athymic mice by tea epigallocatechin gallate.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Catechin; Cell Division; Cell Line; Female; Humans; Male; Mice; Mice, Nude; Prostatic Neoplasms; Structure-Activity Relationship; Tea; Time Factors; Transplantation, Heterologous; Tumor Cells, Cultured | 1995 |
Inhibition of oxidative stress in HeLa cells by chemopreventive agents.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Anticarcinogenic Agents; Antineoplastic Agents; Caffeic Acids; Catechin; Deoxyguanosine; Diterpenes; DNA, Neoplasm; HeLa Cells; Humans; Hydrogen Peroxide; Hydrolyzable Tannins; Oxidation-Reduction; Phenylethyl Alcohol; Tamoxifen; Tannins; Tetradecanoylphorbol Acetate; Thymidine | 1993 |
Effects of various natural antioxidants on the Cu(2+)-mediated oxidative modification of low density lipoprotein.
Topics: Antioxidants; Catechin; Cholesterol; Copper; Electrophoresis, Polyacrylamide Gel; Free Radical Scavengers; Lipoproteins, LDL; Oxidation-Reduction | 1995 |
Absorption of (-)-epigallocatechin gallate into rat portal vein.
Topics: Absorption; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Catechin; Chromatography, High Pressure Liquid; Male; Portal Vein; Rats; Rats, Wistar; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Ultraviolet | 1995 |
Inhibition of N-methyl-N'-nitro-N-nitrosoguanidine-induced carcinogenesis by (-)-epigallocatechin gallate in the rat glandular stomach.
Topics: Adenocarcinoma; Adenoma; Animals; Antineoplastic Agents; Carcinoma, Papillary; Catechin; Drug Screening Assays, Antitumor; Male; Methylnitronitrosoguanidine; Ornithine Decarboxylase; Papilloma; Rats; Rats, Wistar; Stomach Neoplasms | 1995 |
[Mechanism of scavenging effects of (-)-epigallocatechin gallate on active oxygen free radicals].
Topics: Catechin; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Luminescent Measurements; Oxygen | 1994 |
Antibacterial activity of epigallocatechin gallate against methicillin-resistant Staphylococcus aureus.
Topics: Catechin; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus aureus | 1994 |
Epigallocatechin gallate. The major causative agent of green tea-induced asthma.
Topics: Asthma; Bronchial Provocation Tests; Catechin; Dust; Female; Humans; Intradermal Tests; Male; Middle Aged; Occupational Diseases; Skin Tests; Tea | 1994 |
Prevention of heterocyclic amine formation by tea and tea polyphenols.
Topics: Antineoplastic Agents; Biflavonoids; Carcinogens; Catechin; Gallic Acid; Imidazoles; Quinoxalines; Tea | 1994 |
[Effect of catechin on the ultrastructure of Trichophyton mentagrophytes].
Topics: Catechin; Microscopy, Electron, Scanning; Microscopy, Electron, Scanning Transmission; Trichophyton | 1994 |
Inhibition of the infectivity of influenza virus by tea polyphenols.
Topics: Animals; Antiviral Agents; Biflavonoids; Catechin; Cell Line; Dogs; Gallic Acid; Hemagglutination, Viral; Influenza A virus; Influenza B virus; Kidney; Microscopy, Electron, Scanning; Orthomyxoviridae Infections; Plant Extracts; Rabbits; Tea; Viral Plaque Assay | 1993 |
Inhibitory effects of crude drug components on the proliferation of cultured human mesangial cells.
Topics: Catechin; Cell Division; Cells, Cultured; Depression, Chemical; Drugs, Chinese Herbal; Glomerular Mesangium; Humans; Tea | 1993 |
Effects of catechins on the mouse lung carcinoma cell adhesion to the endothelial cells.
Topics: Animals; Catechin; Cattle; Cell Adhesion; Cell Survival; Cells, Cultured; Endothelium, Vascular; Flavonoids; Lung Neoplasms; Mice; Mice, Inbred C57BL; Structure-Activity Relationship; Tumor Cells, Cultured | 1993 |
Anticarcinogenic activity of green tea polyphenols.
Topics: Animals; Antineoplastic Agents; Catechin; Dose-Response Relationship, Drug; Doxorubicin; Estrogens; Flavonoids; Lung Neoplasms; Lyngbya Toxins; Mammary Neoplasms, Experimental; Phenols; Plant Extracts; Polymers; Protein Kinase C; Tea; Tumor Cells, Cultured | 1993 |
Inhibitory effects of tea extracts and (-)-epigallocatechin gallate on DNA synthesis and proliferation of hepatoma and erythroleukemia cells.
Topics: Animals; Catechin; Cell Differentiation; Cell Division; DNA, Neoplasm; Hemoglobins; Leukemia, Erythroblastic, Acute; Liver Neoplasms, Experimental; Mice; Plant Extracts; Rats; Tea | 1993 |
Relationship of oxidative events and DNA oxidation in SENCAR mice to in vivo promoting activity of phorbol ester-type tumor promoters.
Topics: Animals; Carcinogens; Catechin; Diterpenes; DNA; DNA Damage; Female; Hydrogen Peroxide; Inflammation; Mice; Mice, Inbred Strains; Neutrophils; Oxidation-Reduction; Phorbol Esters; Skin; Tamoxifen; Terpenes; Tetradecanoylphorbol Acetate | 1993 |
Chemoprevention of mammary preneoplasia. In vitro effects of a green tea polyphenol.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Adhesion; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Female; Genes, myc; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Precancerous Conditions; Tea; Transfection | 1995 |
Inhibition of 1,2,4-benzenetriol-generated active oxygen species and induction of phase II enzymes by green tea polyphenols.
Topics: Animals; Catalase; Catechin; Cytochrome P-450 Enzyme System; DNA Damage; Enzyme Induction; Ferrous Compounds; Flavonoids; Hydrogen Peroxide; Hydroquinones; Hydroxyl Radical; Injections, Intraperitoneal; Liver; Male; Microsomes, Liver; Oxidation-Reduction; Oxidoreductases; Phenols; Polymers; Pyrogallol; Rats; Rats, Wistar; Reactive Oxygen Species; Tea | 1995 |
Inhibition of oncogene expression by green tea and (-)-epigallocatechin gallate in mice.
Topics: Animals; Antineoplastic Agents; Carcinogens; Catechin; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, myc; Genes, ras; Lung; Mice; Nitrosamines; Oncogenes; Ornithine Decarboxylase; Platelet-Derived Growth Factor; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins c-sis; Proto-Oncogene Proteins p21(ras); Skin; Tea; Tetradecanoylphorbol Acetate | 1995 |
Inhibitory effects and toxicity of green tea polyphenols for gastrointestinal carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Catechin; Gastrointestinal Neoplasms; Male; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mutagenicity Tests; Plant Extracts; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Tea | 1996 |
Inhibitory effects of green tea polyphenols on growth and cellular adherence of an oral bacterium, Porphyromonas gingivalis.
Topics: Bacterial Adhesion; Catechin; Cheek; Enzyme Inhibitors; Epithelial Cells; Epithelium; Flavonoids; Humans; Microbial Sensitivity Tests; Mouth Mucosa; Phenols; Plant Extracts; Polymers; Porphyromonas gingivalis; Structure-Activity Relationship; Tea | 1996 |
A new process of cancer prevention mediated through inhibition of tumor necrosis factor alpha expression.
Topics: 3T3 Cells; Animals; Anticarcinogenic Agents; Base Sequence; Catechin; Cyclohexanols; Diterpenes; Humans; Mice; Molecular Sequence Data; Proto-Oncogenes; Tamoxifen; Tumor Necrosis Factor-alpha | 1996 |
Protecting effect of a green tea percolate and its main constituents against gamma ray-induced scission of DNA.
Topics: Antimutagenic Agents; Ascorbic Acid; Catechin; DNA Damage; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Free Radical Scavengers; Gamma Rays; Hydroxyl Radical; Plant Extracts; Plasmids; Stereoisomerism; Tea | 1996 |
Mutagenic potential of peripheral blood leukocytes: in vivo exposure to the carcinogen 7,12-dimethylbenz[a]anthracene, and the tumor promoter 12-O-tetradecanoylphorbol acetate followed by in vitro co-culture with AS52 cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Catechin; CHO Cells; Coculture Techniques; Cricetinae; Female; Hypoxanthine Phosphoribosyltransferase; Leukocytes; Mice; Mice, Inbred Strains; Mutagenicity Tests; Mutagens; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection | 1996 |
(-)-Epigallocatechin gallate, a polyphenolic tea antioxidant, inhibits peroxynitrite-mediated formation of 8-oxodeoxyguanosine and 3-nitrotyrosine.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Catechin; Cattle; Deoxyguanosine; DNA; Free Radical Scavengers; Nitrates; Oxidation-Reduction; Tea; Tyrosine | 1996 |
Inhibitory effect of tea polyphenols on histamine and leukotriene B4 release from rat peritoneal exudate cells.
Topics: Animals; Ascitic Fluid; Calcimycin; Catechin; Flavonoids; Histamine Release; Leukotriene B4; Male; p-Methoxy-N-methylphenethylamine; Phenols; Polymers; Rats; Rats, Wistar; Tea | 1996 |
Effect of plant phenolics on the formation of the spin-adduct of hydroxyl radical and the DNA strand breaking by hydroxyl radical.
Topics: Catechin; Cyclic N-Oxides; DNA Adducts; DNA Damage; Electron Spin Resonance Spectroscopy; Electrophoresis, Agar Gel; Flavonoids; Hydrogen Peroxide; Hydroxyl Radical; Iron; Molecular Structure; Phenols; Plants; Polymers; Spin Labels; Spin Trapping | 1996 |
Prevention of photocarcinogenesis by topical administration of pure epigallocatechin gallate isolated from green tea.
Topics: Administration, Topical; Animals; Antigens, Neoplasm; Antineoplastic Agents; Catechin; Female; Immune Tolerance; Mice; Mice, Inbred BALB C; Skin Neoplasms; Tea; Ultraviolet Rays | 1996 |
[(-)-Epigallocatechin gallate, the main constituent of Japanese green tea, inhibits tumor promotion of okadaic acid].
Topics: Animals; Antineoplastic Agents; Binding Sites; Carcinogens; Catechin; Mice; Okadaic Acid; Skin Neoplasms; Tea | 1996 |
Bio-antimutagenic activity of green tea catechins in cultured Chinese hamster V79 cells.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antimutagenic Agents; Catechin; Cell Line; Cricetinae; Cricetulus; Lethal Dose 50; Male; Mutagens; Tea | 1996 |
Evidence for the interaction between (-)-epigallocatechin gallate and human plasma proteins fibronectin, fibrinogen, and histidine-rich glycoprotein.
Topics: Antineoplastic Agents; Blood Proteins; Catechin; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Fibronectins; Humans; Intestinal Absorption; Molecular Weight; Proteins | 1996 |
Effects of tea (Camellia sinensis) chemical compounds on ethanol metabolism in ICR mice.
Topics: Acetaldehyde; Acetates; Acetone; Administration, Oral; Alcoholic Intoxication; Animals; Caffeine; Catechin; Ethanol; Flavonoids; Liver; Male; Mice; Mice, Inbred ICR; Plant Extracts; Tea | 1996 |
Effect of (-)-epigallocatechin gallate on leukemic blast cells from patients with acute myeloblastic leukemia.
Topics: Blast Crisis; Catechin; Cell Division; Cell Line; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Tea; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Inhibitory action of (-)-epigallocatechin gallate on radiation-induced mouse oncogenic transformation.
Topics: Animals; Catechin; Cell Survival; Cell Transformation, Neoplastic; Fibroblasts; Kinetics; Mice; Mice, Inbred C3H; Oncogenes; Quercetin; Tea; X-Rays | 1997 |
Effects of green tea catechins on the progression or late promotion stage of mammary gland carcinogenesis in female Sprague-Dawley rats pretreated with 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Body Weight; Carcinogens; Catechin; Disease Progression; Female; Mammary Neoplasms, Experimental; Neoplasm Staging; Rats; Rats, Sprague-Dawley; Tea | 1997 |
Protection against induction of mouse skin papillomas with low and high risk of conversion to malignancy by green tea polyphenols.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Carcinoma, Squamous Cell; Catechin; Cocarcinogenesis; Disease Progression; Diterpenes; Flavonoids; Mice; Mice, Inbred SENCAR; Papilloma; Phenols; Plant Extracts; Polymers; Skin Neoplasms; Tea; Terpenes | 1997 |
Green tea catechins (EGCG and EGC) have modulating effects on the activity of doxorubicin in drug-resistant cell lines.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Catechin; Cell Division; Colonic Neoplasms; Doxorubicin; Drug Resistance, Neoplasm; Flavonoids; Humans; Mice; Sarcoma 180; Tea; Tumor Cells, Cultured | 1997 |
Clinical development plan: tea extracts. Green tea polyphenols. Epigallocatechin gallate.
Topics: Animals; Anticarcinogenic Agents; Catechin; Dogs; Drug Approval; Female; Flavonoids; Humans; Male; Mice; Neoplasms; Neoplasms, Experimental; Phenols; Plant Extracts; Polymers; Rats; Research Design; Tea | 1996 |
Sealing effects of (-)-epigallocatechin gallate on protein kinase C and protein phosphatase 2A.
Topics: Catechin; Circular Dichroism; Enzyme Inhibitors; Lipid Bilayers; Liposomes; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase C; Protein Phosphatase 2; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1997 |
Why drinking green tea could prevent cancer.
Topics: Animals; Anticarcinogenic Agents; Catechin; Computer Simulation; Enzyme Inhibitors; Humans; Neoplasms; Tea; Urokinase-Type Plasminogen Activator | 1997 |
Chemiluminescence-high-performance liquid chromatographic determination of tea catechin, (-)-epigallocatechin 3-gallate, at picomole levels in rat and human plasma.
Topics: Adult; Animals; Anticarcinogenic Agents; Antimutagenic Agents; Catechin; Chromatography, High Pressure Liquid; Humans; Luminescent Measurements; Male; Microchemistry; Molecular Structure; Rats; Rats, Wistar; Sensitivity and Specificity; Tea | 1997 |
Epigallocatechin gallate-induced histamine release in patients with green tea-induced asthma.
Topics: Adult; Antimutagenic Agents; Asthma; Catechin; Female; Histamine Release; Humans; Male; Middle Aged; Skin Tests; Tea | 1997 |
Inhibitory effects of jasmine green tea epicatechin isomers on free radical-induced lysis of red blood cells.
Topics: Amidines; Animals; Antioxidants; Catechin; Dose-Response Relationship, Drug; Erythrocyte Membrane; Fatty Acids; Flavonoids; Free Radicals; Hemolysis; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Tea | 1997 |
Inhibitory effects of persimmon (Diospyros kaki) extract and related polyphenol compounds on growth of human lymphoid leukemia cells.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Division; DNA Fragmentation; Flavonoids; Fruit; Humans; Leukemia, Lymphoid; Microscopy, Fluorescence; Ornithine Decarboxylase; Phenols; Plant Extracts; Polymers; Tumor Cells, Cultured | 1997 |
[Effect of tea extracts, catechin and caffeine against type-I allergic reaction].
Topics: Administration, Oral; Animals; Caffeine; Catechin; Depression, Chemical; Flavonoids; Hypersensitivity, Immediate; Male; Passive Cutaneous Anaphylaxis; Plant Extracts; Rats; Rats, Wistar; Tea | 1997 |
Inhibitory activity of green and black tea in a free radical-generating system using 2-amino-3-methylimidazo[4,5-f]quinoline as substrate.
Topics: Animals; Anticarcinogenic Agents; Catechin; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Kinetics; Meat; Mutagens; NADPH-Ferrihemoprotein Reductase; Quinolines; Rats; Spin Labels; Tea | 1997 |
(-)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kappaB.
Topics: Animals; Caffeine; Catechin; Down-Regulation; Enzyme Inhibitors; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nuclear Proteins; Phenols; Phosphodiesterase Inhibitors; Proto-Oncogene Proteins; Tea; Transcription Factor RelB; Transcription Factors | 1997 |
Inhibition of carcinogenesis by tea.
Topics: Animals; Anticarcinogenic Agents; Catechin; Humans; Tea | 1997 |
Mechanisms of growth inhibition of human lung cancer cell line, PC-9, by tea polyphenols.
Topics: Antineoplastic Agents; Catechin; Cell Cycle; Cell Division; Humans; Lung Neoplasms; Phenols; Tea; Tritium; Tumor Cells, Cultured | 1997 |
Absorption, distribution, elimination of tea polyphenols in rats.
Topics: Administration, Oral; Animals; Area Under Curve; Biological Availability; Catechin; Flavonoids; Half-Life; Injections, Intravenous; Kidney; Liver; Lung; Male; Metabolic Clearance Rate; Rats; Rats, Sprague-Dawley; Tea | 1997 |
Suppression of extracellular signals and cell proliferation through EGF receptor binding by (-)-epigallocatechin gallate in human A431 epidermoid carcinoma cells.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Catechin; Cell Division; DNA, Neoplasm; Epidermal Growth Factor; ErbB Receptors; Humans; Ligands; Phosphotyrosine; Receptor Protein-Tyrosine Kinases; Receptors, Fibroblast Growth Factor; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Tea; Tumor Cells, Cultured | 1997 |
Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate, and theaflavins.
Topics: Animals; Anticarcinogenic Agents; Biflavonoids; Catechin; Cell Transformation, Neoplastic; Chemoprevention; Epidermal Growth Factor; Mice; Phosphorylation; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-jun; Signal Transduction; Tea; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation | 1997 |
Inhibition of collagenases from mouse lung carcinoma cells by green tea catechins and black tea theaflavins.
Topics: Animals; Antioxidants; Biflavonoids; Carcinoma; Catechin; Free Radical Scavengers; Gallic Acid; Lung Neoplasms; Matrix Metalloproteinase Inhibitors; Mice; Tea; Tumor Cells, Cultured | 1997 |
Beta ray-induced scission of DNA in tritiated water and protection by a green tea percolate and (-)-epigallocatechin gallate.
Topics: Beta Particles; Catechin; Deuterium Oxide; DNA Damage; DNA, Bacterial; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radical Scavengers; Indicators and Reagents; Plant Extracts; Plasmids; Tea | 1997 |
Inhibition of inducible nitric oxide synthase gene expression and enzyme activity by epigallocatechin gallate, a natural product from green tea.
Topics: Animals; Catechin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase; Tea | 1997 |
Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Catechin; Cell Cycle; Electrophoresis, Agar Gel; Flow Cytometry; Humans; Mice; Microscopy, Confocal; Tea; Tumor Cells, Cultured | 1997 |
Effect of tea extracts, polyphenols, and epigallocatechin gallate on azoxymethane-induced colon cancer.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Catechin; Colonic Neoplasms; Flavonoids; Male; Phenols; Phytotherapy; Plant Extracts; Polymers; Rats; Rats, Inbred F344; Tea | 1998 |
Quantitation of chemopreventive synergism between (-)-epigallocatechin-3-gallate and curcumin in normal, premalignant and malignant human oral epithelial cells.
Topics: Anticarcinogenic Agents; Catechin; Cells, Cultured; Curcumin; Dose-Response Relationship, Drug; Drug Synergism; Epithelial Cells; Flow Cytometry; Humans; Mouth Neoplasms; Precancerous Conditions; Tea | 1998 |
Absorption and distribution of tea catechin, (-)-epigallocatechin-3-gallate, in the rat.
Topics: Animals; Catechin; Chromatography, High Pressure Liquid; Luminescent Measurements; Rats; Tea; Tissue Distribution | 1997 |
Erythrocyte-dependent mitogenic activity of epigallocatechin gallate on mouse splenic B cells.
Topics: Animals; B-Lymphocytes; Catechin; Erythrocytes; Lymphocyte Activation; Male; Mice; Mice, Inbred C3H; Mitogens; Rabbits | 1997 |
Influence of drinking green tea on breast cancer malignancy among Japanese patients.
Topics: Adult; Alcohol Drinking; Anticarcinogenic Agents; Beverages; Breast Neoplasms; Catechin; Diet; Disease-Free Survival; Female; Follow-Up Studies; Humans; Japan; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Smoking; Tea | 1998 |
Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Division; Colonic Neoplasms; Humans; Lung Neoplasms; Superoxide Dismutase; Tea; Tumor Cells, Cultured | 1998 |
Involvement of protein tyrosine phosphorylation in the effect of green tea polyphenols on Ehrlich ascites tumor cells in vitro.
Topics: Animals; Anticarcinogenic Agents; Carcinoma, Ehrlich Tumor; Catechin; Cell Survival; Flavonoids; Kinetics; Mice; Neoplasm Proteins; Ornithine Decarboxylase; Phenols; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tea; Tumor Cells, Cultured | 1998 |
Interaction between the carboxyl-terminal heparin-binding domain of fibronectin and (-)-epigallocatechin gallate.
Topics: Antineoplastic Agents; Catechin; Cell Adhesion; Fibronectins; Humans; Lung Neoplasms | 1998 |
Cancer inhibition by green tea.
Topics: 3T3 Cells; Animals; Anticarcinogenic Agents; Biological Availability; Catechin; Female; Humans; Male; Mice; Neoplasms; Tea; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
Catechin metabolites after intake of green tea infusions.
Topics: Antioxidants; Benzoates; Catechin; Humans; Tea | 1998 |
Green tea regulates cell cycle progression in oral leukoplakia.
Topics: Anticarcinogenic Agents; Blotting, Western; Carcinoma, Squamous Cell; Catechin; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Child, Preschool; Humans; Leukoplakia, Oral; Models, Biological; Mouth Mucosa; Phytotherapy; Sensitivity and Specificity; Skin Neoplasms; Tea | 1998 |
Telomerase inhibition, telomere shortening, and senescence of cancer cells by tea catechins.
Topics: Adenocarcinoma; Antineoplastic Agents; beta-Galactosidase; Catechin; Cell-Free System; Cellular Senescence; Colonic Neoplasms; Enzyme Inhibitors; Humans; Kinetics; Leukemia, Monocytic, Acute; Neoplasms; Tea; Telomerase; Telomere; Tumor Cells, Cultured | 1998 |
Green tea epigallocatechin gallate shows a pronounced growth inhibitory effect on cancerous cells but not on their normal counterparts.
Topics: Anticarcinogenic Agents; Apoptosis; Breast; Breast Neoplasms; Catechin; Cell Division; Cell Line, Transformed; Cells, Cultured; Colon; Colonic Neoplasms; Female; Fibroblasts; Gene Expression; Genes, fos; Genes, myc; Humans; Microscopy, Fluorescence; Neoplasms; RNA, Messenger; Tea; Tumor Cells, Cultured | 1998 |
Inhibition of linoleic acid hydroperoxide-induced toxicity in cultured human umbilical vein endothelial cells by catechins.
Topics: Catechin; Cells, Cultured; Drug Interactions; Endothelium, Vascular; Flavonoids; Free Radical Scavengers; Humans; Linoleic Acids; Lipid Peroxides; Oxidative Stress; Structure-Activity Relationship; Umbilical Veins; Vitamin E | 1998 |
Induction of apoptosis in prostate cancer cell lines by the green tea component, (-)-epigallocatechin-3-gallate.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Count; Drug Screening Assays, Antitumor; Flavonoids; Humans; Male; Phenols; Polymers; Prostatic Neoplasms; Tea; Tumor Cells, Cultured | 1998 |
Wide distribution of [3H](-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue.
Topics: Animals; Anticarcinogenic Agents; Autoradiography; Catechin; Feces; Female; Male; Mice; Tea; Tissue Distribution; Tritium | 1998 |
Green tea polyphenols block endotoxin-induced tumor necrosis factor-production and lethality in a murine model.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Catechin; Cell Line; Disease Models, Animal; Down-Regulation; Flavonoids; Gene Expression Regulation; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Phenols; Polymers; Tea; Tumor Necrosis Factor-alpha | 1998 |
Synthesis and antioxidant activity of novel amphipathic derivatives of tea polyphenol.
Topics: Antioxidants; Catechin; Lipid Bilayers; Lipid Peroxidation; Tea | 1998 |
(-)-Epigallocatechin-3-gallate inhibition of ultraviolet B-induced AP-1 activity.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Line; Humans; Keratinocytes; Mice; Mice, Transgenic; Sensitivity and Specificity; Skin Neoplasms; Tea; Transcription Factor AP-1; Ultraviolet Rays | 1998 |
Synergistic effects of (--)-epigallocatechin gallate with (--)-epicatechin, sulindac, or tamoxifen on cancer-preventive activity in the human lung cancer cell line PC-9.
Topics: 3T3 Cells; Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Humans; Lung Neoplasms; Mice; Sulindac; Tamoxifen; Tea; Tumor Cells, Cultured | 1999 |
Human salivary tea catechin levels and catechin esterase activities: implication in human cancer prevention studies.
Topics: Absorption; Adult; Anticarcinogenic Agents; Beverages; Capsules; Catechin; Drinking; Esophageal Neoplasms; Esterases; Female; Flavonoids; Free Radical Scavengers; Half-Life; Humans; Male; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Saliva; Tea | 1999 |
Growth inhibition of leukemic cells by (-)-epigallocatechin gallate, the main constituent of green tea.
Topics: Animals; Antineoplastic Agents; Apoptosis; Catechin; Cell Division; Cell Lineage; Cell Survival; Cells, Cultured; DNA; DNA Fragmentation; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Interleukin-3; Leukemia; Mice; Tea; Tumor Cells, Cultured | 1998 |
Pharmacokinetics of the green tea derivative, EGCG, by the topical route of administration in mouse and human skin.
Topics: Administration, Topical; Animals; Anticarcinogenic Agents; Catechin; Female; Humans; In Vitro Techniques; Mice; Mice, Inbred BALB C; Permeability; Skin; Skin Absorption; Tea; Time Factors | 1999 |
Inhibition of ultraviolet B--induced c-fos gene expression and p38 mitogen-activated protein kinase activation by (-)-epigallocatechin gallate in a human keratinocyte cell line.
Topics: Anticarcinogenic Agents; Calcium-Calmodulin-Dependent Protein Kinases; Catechin; Cell Line; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, fos; Humans; Keratinocytes; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Tea; Ultraviolet Rays | 1999 |
Ingredient in green tea kills prostate cancer cells, study finds.
Topics: Antineoplastic Agents; Catechin; Humans; Male; Prostatic Neoplasms; Tea; Tumor Cells, Cultured | 1999 |
Inhibition of benzo[a]pyrene-induced mutagenesis by (-)-epigallocatechin gallate in the lung of rpsL transgenic mice.
Topics: Animals; Antimutagenic Agents; Base Sequence; Benzo(a)pyrene; Catechin; DNA Primers; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutagens; Mutation; Tea | 1999 |
Methylation of tea catechins by rat liver homogenates.
Topics: Animals; Catechin; Chromatography, High Pressure Liquid; Flavonoids; Liver; Magnetic Resonance Spectroscopy; Male; Methylation; Rats; Rats, Wistar; S-Adenosylmethionine; Spectrometry, Mass, Fast Atom Bombardment; Tea | 1999 |
Epigallocathechin-3 gallate selectively inhibits the PDGF-BB-induced intracellular signaling transduction pathway in vascular smooth muscle cells and inhibits transformation of sis-transfected NIH 3T3 fibroblasts and human glioblastoma cells (A172).
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Aorta; Becaplermin; Brain Neoplasms; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Catechin; Cell Transformation, Neoplastic; Cells, Cultured; Glioblastoma; Humans; Kinetics; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Oncogene Proteins v-sis; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Inbred WKY; Recombinant Proteins; Retroviridae Proteins, Oncogenic; Signal Transduction; Tea; Transfection; Tumor Cells, Cultured | 1999 |
Angiogenesis inhibited by drinking tea.
Topics: Animals; Catechin; Cattle; Corneal Neovascularization; Drinking; Endothelium, Vascular; Mice; Neovascularization, Pathologic; Rats; Tea; Tumor Cells, Cultured | 1999 |
Antioxidant chemistry of green tea catechins. Identification of products of the reaction of (-)-epigallocatechin gallate with peroxyl radicals.
Topics: Antioxidants; Catechin; Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Peroxides; Tea | 1999 |
Suppression of extracellular signals and cell proliferation by the black tea polyphenol, theaflavin-3,3'-digallate.
Topics: 3T3 Cells; Animals; Biflavonoids; Carcinoma, Squamous Cell; Catechin; Cell Division; Epidermal Growth Factor; ErbB Receptors; Gallic Acid; Growth Inhibitors; Humans; Laryngeal Neoplasms; Mice; Phenols; Phosphorylation; Platelet-Derived Growth Factor; Polyphenols; Protein Binding; Protein Processing, Post-Translational; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Tea; Tumor Cells, Cultured | 1999 |
Effects of green tea catechins on membrane fluidity.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Catechin; Chlorhexidine; Dose-Response Relationship, Drug; Fluorescence Polarization; Humans; Membrane Fluidity; Phosphatidylcholines; Tea | 1999 |
The green tea extract epigallocatechin gallate is able to reduce neutrophil transmigration through monolayers of endothelial cells.
Topics: Catechin; Cell Migration Inhibition; Cells, Cultured; Endothelium, Vascular; Humans; Leukocyte Migration-Inhibitory Factors; Neutrophils; Tea | 1999 |
Theoretical elucidation of activity differences of five phenolic antioxidants.
Topics: Acetophenones; Antioxidants; Catechin; Coumaric Acids; Free Radicals; Molecular Structure; Rutin; Structure-Activity Relationship | 1999 |
Inhibition of cyclin-dependent kinases 2 and 4 activities as well as induction of Cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by (-)-epigallocatechin-3-gallate.
Topics: Catechin; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cell Division; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Microtubule-Associated Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Retinoblastoma Protein; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 1999 |
Mechanistic aspects of green tea as a cancer preventive: effect of components on human stomach cancer cell lines.
Topics: 3T3 Cells; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Catechin; Cell Division; Flavonoids; Gene Expression; Humans; Mice; Mice, Inbred BALB C; NF-kappa B; Okadaic Acid; Phenols; Phytotherapy; Polymers; Stomach Neoplasms; Tea; Transcription Factor AP-1; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Inhibition of eleven mutagens by various tea extracts, (-)epigallocatechin-3-gallate, gallic acid and caffeine.
Topics: Animals; Antimutagenic Agents; Caffeine; Catechin; Drug Interactions; Gallic Acid; In Vitro Techniques; Mutagenicity Tests; Plant Extracts; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Tea | 1999 |
Scavenging mechanisms of (-)-epigallocatechin gallate and (-)-epicatechin gallate on peroxyl radicals and formation of superoxide during the inhibitory action.
Topics: Amidines; Antioxidants; Catechin; Enzyme Inhibitors; Free Radical Scavengers; Kinetics; Lipid Peroxidation; Liposomes; Luminescent Measurements; Mass Spectrometry; Molecular Structure; Peroxides; Quantum Theory; Spectrophotometry; Superoxide Dismutase; Superoxides; Thermodynamics | 1999 |
Green tea and cancer chemoprevention.
Topics: 3T3 Cells; Animals; Apoptosis; Biological Availability; Breast Neoplasms; Case-Control Studies; Catechin; Drug Synergism; Female; Humans; Japan; Male; Mice; Neoplasms; Sulindac; Tea; Tissue Distribution; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
[Multiple actions of EGCG, the main component of green tea].
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Division; Humans; Neovascularization, Pathologic; Tea | 1999 |
Two stages of cancer prevention with green tea.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Division; Cohort Studies; Drug Synergism; Female; Humans; Kava; Male; Neoplasms; Phytotherapy; Plants, Medicinal; Prospective Studies; Sulindac; Tea; Tissue Distribution; Tumor Necrosis Factor-alpha | 1999 |
Prevention of UVB-induced immunosuppression in mice by the green tea polyphenol (-)-epigallocatechin-3-gallate may be associated with alterations in IL-10 and IL-12 production.
Topics: Administration, Topical; Animals; Anticarcinogenic Agents; Catechin; Female; Immune System; Interleukin-10; Interleukin-12; Mice; Mice, Inbred C3H; Tea; Ultraviolet Rays | 1999 |
Tumor invasion: molecular shears blunted by green tea.
Topics: Angiogenesis Inhibitors; Catechin; Matrix Metalloproteinase Inhibitors; Neoplasm Invasiveness; Protease Inhibitors; Tea; Tumor Cells, Cultured | 1999 |
Regeneration of alpha-tocopherol in human low-density lipoprotein by green tea catechin.
Topics: Amidines; Catechin; Flavonoids; Humans; Lipoproteins, LDL; Oxidants; Tea; Vitamin E | 1999 |
Inhibition of Df-protease associated with allergic diseases by polyphenol.
Topics: Animals; Catechin; Flavonoids; Humans; Hypersensitivity; Kinetics; Kinins; Mites; Phenols; Polymers; Protease Inhibitors; Serine Endopeptidases | 1999 |
Epigallocatechin gallate and gallocatechin gallate in green tea catechins inhibit extracellular release of Vero toxin from enterohemorrhagic Escherichia coli O157:H7.
Topics: Bacterial Proteins; Bacterial Toxins; Catechin; Cell Extracts; Escherichia coli O157; Flavonoids; Periplasm; Shiga Toxin 1; Tea | 1999 |
Effects of green tea polyphenols on lens photooxidative stress.
Topics: Animals; Catalase; Catechin; Dogfish; Flavonoids; Lens, Crystalline; Oxidative Stress; Phenols; Polymers; Rabbits; Radiation-Protective Agents; Tea; Ultraviolet Rays | 1999 |
Antithrombotic activities of green tea catechins and (-)-epigallocatechin gallate.
Topics: Adenosine Diphosphate; Animals; Aspirin; Bleeding Time; Calcimycin; Calcium; Catechin; Collagen; Epinephrine; Fibrinolytic Agents; Humans; Ion Transport; Ionophores; Male; Mice; Mice, Inbred ICR; Platelet Aggregation; Platelet Aggregation Inhibitors; Pulmonary Embolism; Rats; Rats, Sprague-Dawley; Tea | 1999 |
The effect of epigallocatechin galleate and sarcophytol A on DNA strand breakage induced by tobacco-specific nitrosamines and stimulated human phagocytes.
Topics: Anticarcinogenic Agents; Catechin; Cells, Cultured; Diterpenes; DNA; DNA Damage; Free Radicals; Humans; Hydrogen Peroxide; Lung; Nicotiana; Nitrosamines; Oxidative Stress; Phagocytes; Plants, Toxic; Reactive Oxygen Species; Superoxides; Tea; Tetradecanoylphorbol Acetate | 1999 |
(-)-Epigallocatechin gallate inhibits mos activation-mediated xenopus oocyte maturation induced by progesterone.
Topics: Animals; Anticarcinogenic Agents; Catechin; Enzyme Activation; Female; Gene Expression Regulation; Genes, mos; Microinjections; Mitogen-Activated Protein Kinases; Oocytes; Phosphorylation; Progesterone; Ribosomal Protein S6 Kinases; Stereoisomerism; Tea; Xenopus laevis | 1999 |
Radical scavenging activity of tea catechins and their related compounds.
Topics: Bepridil; Biphenyl Compounds; Catechin; Free Radical Scavengers; Hydroxyl Radical; In Vitro Techniques; Picrates; Superoxides; Tea | 1999 |
DNA cleavage activities of (-)-epigallocatechin, (-)-epicatechin, (+)-catechin, and (-)-epigallocatechin gallate with various kinds of metal ions.
Topics: Animals; Antioxidants; Catechin; Cattle; Copper; DNA; DNA Damage; Flavonoids; In Vitro Techniques; Metals; Oxidants; Silver; Structure-Activity Relationship | 1999 |
Antifungal activity of (-)-epigallocatechin gallate from Coccoloba dugandiana.
Topics: Antifungal Agents; Catechin; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Polygonaceae | 1999 |
Antioxidant capacity of flavanols and gallate esters: pulse radiolysis studies.
Topics: Anions; Antioxidants; Azides; Catechin; Flavonoids; Flavonols; Free Radicals; Hydrolyzable Tannins; Hydroxyl Radical; Kinetics; Pulse Radiolysis; Spectrophotometry; Superoxides; Tannins | 1999 |
Interaction of tea catechins with lipid bilayers investigated with liposome systems.
Topics: Catechin; Dose-Response Relationship, Drug; Flavonoids; Lipid Bilayers; Liposomes; Models, Chemical; Phenols; Polymers; Tea | 1999 |
Electron paramagnetic resonance studies of radical species of proanthocyanidins and gallate esters.
Topics: Anthocyanins; Catechin; Electron Spin Resonance Spectroscopy; Esters; Flavonoids; Free Radicals; Horseradish Peroxidase; Hydrogen Peroxide; Hydrogen-Ion Concentration; Molecular Conformation; Molecular Structure; Oxidation-Reduction; Tannins | 2000 |
Modulation of endocrine systems and food intake by green tea epigallocatechin gallate.
Topics: Animals; Blood Cell Count; Blood Chemical Analysis; Body Weight; Catechin; Eating; Endocrine Glands; Female; Genitalia; Gonadal Steroid Hormones; Growth Hormone; Insulin; Insulin-Like Growth Factor I; Leptin; Luteinizing Hormone; Male; Organ Size; Rats; Rats, Sprague-Dawley; Rats, Zucker; Tea; Testosterone | 2000 |
Efficacies of tea components on doxorubicin induced antitumor activity and reversal of multidrug resistance.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caffeine; Calcium Channel Blockers; Carcinoma, Ehrlich Tumor; Catechin; Doxorubicin; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Drug Synergism; Flavonoids; Glutamates; Intracellular Fluid; Leukemia P388; Male; Mice; Neoplasm Transplantation; Phytotherapy; Tea; Theobromine; Verapamil | 2000 |
Matrix metalloproteinase inhibition by green tea catechins.
Topics: Animals; Catechin; Cell Line; Concanavalin A; Cricetinae; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; Gelatinases; Guanosine Triphosphate; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Mice; Molecular Structure; Swine; Tea | 2000 |
Growth inhibition, cell-cycle dysregulation, and induction of apoptosis by green tea constituent (-)-epigallocatechin-3-gallate in androgen-sensitive and androgen-insensitive human prostate carcinoma cells.
Topics: Androgens; Antineoplastic Agents; Apoptosis; Catechin; Cell Cycle; Cell Division; Humans; Male; Prostatic Neoplasms; Tumor Cells, Cultured | 2000 |
Green tea polyphenols induce apoptosis in vitro in peripheral blood T lymphocytes of adult T-cell leukemia patients.
Topics: Adult; Aged; Anticarcinogenic Agents; Apoptosis; Case-Control Studies; Catechin; Cell Division; DNA Fragmentation; Dose-Response Relationship, Drug; Female; Flavonoids; Gene Expression; Human T-lymphotropic virus 1; Humans; In Situ Nick-End Labeling; Leukemia-Lymphoma, Adult T-Cell; Leukemia, T-Cell; Leukocytes, Mononuclear; Male; Middle Aged; Phenols; Phytotherapy; Polymers; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; T-Lymphocytes; Tea; Tumor Cells, Cultured | 2000 |
Involvement of caspase-3 in epigallocatechin-3-gallate-mediated apoptosis of human chondrosarcoma cells.
Topics: Antineoplastic Agents; Apoptosis; Bone Neoplasms; Caspase 3; Caspases; Catechin; Cell Survival; Chondrosarcoma; Cysteine Proteinase Inhibitors; Humans; Kinetics; Tumor Cells, Cultured | 2000 |
Tea polyphenols down-regulate the expression of the androgen receptor in LNCaP prostate cancer cells.
Topics: 5' Untranslated Regions; Catechin; Cell Division; Down-Regulation; Flavonoids; Gene Expression Regulation; Humans; Male; Phenols; Polymers; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Regulatory Sequences, Nucleic Acid; Sp1 Transcription Factor; Tea; Tissue Kallikreins; Tumor Cells, Cultured | 2000 |
Identification of oxidation products of (-)-epigallocatechin gallate and (-)-epigallocatechin with H(2)O(2).
Topics: Antioxidants; Catechin; Flavonoids; Hydrogen Peroxide; Molecular Conformation; Molecular Structure; Oxidation-Reduction; Tea | 2000 |
Green tea polyphenol epigallocatechin-3-gallate differentially modulates nuclear factor kappaB in cancer cells versus normal cells.
Topics: Apoptosis; Catechin; Cell Division; Cell Nucleus; Cells, Cultured; Cytoplasm; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; I-kappa B Proteins; Keratinocytes; Lipopolysaccharides; Models, Biological; NF-kappa B; NF-KappaB Inhibitor alpha; Tea; Transcription Factor RelA; Transcriptional Activation; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
(-)-Epigallocatechin gallate can prevent cisplatin-induced lung tumorigenesis in A/J mice.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cisplatin; Female; Lung Neoplasms; Mice | 2000 |
Effects of tea polyphenols on the invasion and matrix metalloproteinases activities of human fibrosarcoma HT1080 cells.
Topics: Antioxidants; Biflavonoids; Catechin; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Fibrosarcoma; Humans; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Neoplasm Invasiveness; Tea; Tumor Cells, Cultured; Umbilical Veins | 1999 |
Growth factor-dependent induction of p21(CIP1) by the green tea polyphenol, epigallocatechin gallate.
Topics: Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Catechin; Cell Cycle; Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Epidermal Growth Factor; Growth Substances; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Retinoblastoma Protein; Signal Transduction; Tea; Time Factors | 2000 |
Effects of epigallocatechin gallate and quercetin on oxidative damage to cellular DNA.
Topics: Antioxidants; Bepridil; Biphenyl Compounds; Catechin; Comet Assay; DNA; DNA Damage; Flavanones; Flavonoids; Free Radical Scavengers; Genistein; Hesperidin; Humans; Indicators and Reagents; Isoflavones; Jurkat Cells; Molsidomine; Nitric Oxide Donors; Oxidation-Reduction; Picrates; Quercetin | 2000 |
Protective effects of the green tea polyphenol (-)-epigallocatechin gallate against hippocampal neuronal damage after transient global ischemia in gerbils.
Topics: Animals; Antioxidants; Catechin; Dose-Response Relationship, Drug; Free Radical Scavengers; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Lipid Peroxidation; Male; Neurons; Neuroprotective Agents; Tea | 2000 |
Artifacts in cell culture: rapid generation of hydrogen peroxide on addition of (-)-epigallocatechin, (-)-epigallocatechin gallate, (+)-catechin, and quercetin to commonly used cell culture media.
Topics: Artifacts; Catechin; Cell Culture Techniques; Culture Media; Dose-Response Relationship, Drug; Flavonoids; Hydrogen Peroxide; Quercetin; Time Factors | 2000 |
Antioxidative effects of green tea polyphenols on free radical initiated and photosensitized peroxidation of human low density lipoprotein.
Topics: Antioxidants; Catechin; Flavonoids; Free Radicals; Gallic Acid; Humans; In Vitro Techniques; Kinetics; Lipid Peroxidation; Lipoproteins, LDL; Phenols; Photochemistry; Polymers; Tea | 2000 |
Induction of oxidatively modified proteins in skeletal muscle by electrical stimulation and its suppression by dietary supplementation of (-)-epigallocatechin gallate.
Topics: Animals; Antioxidants; Body Weight; Catechin; Dietary Supplements; Electric Stimulation; Free Radical Scavengers; Glutathione Peroxidase; Glutathione Transferase; Male; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2000 |
Green tea experiments in lab, clinic yield mixed results.
Topics: Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Antioxidants; Beverages; Catechin; China; Clinical Trials as Topic; Endothelial Growth Factors; Flavonoids; Humans; Lymphokines; Neoplasms; Phenols; Phytotherapy; Polymers; Randomized Controlled Trials as Topic; Tea; Treatment Outcome; United States; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
Inhibition of xanthine oxidase and suppression of intracellular reactive oxygen species in HL-60 cells by theaflavin-3,3'-digallate, (-)-epigallocatechin-3-gallate, and propyl gallate.
Topics: Antioxidants; Biflavonoids; Catechin; Gallic Acid; HL-60 Cells; Humans; Hydrogen Peroxide; Models, Chemical; Propyl Gallate; Reactive Oxygen Species; Structure-Activity Relationship; Superoxides; Tea; Xanthine Oxidase | 2000 |
Oral absorption and bioavailability of tea catechins.
Topics: Absorption; Administration, Oral; Animals; Biological Availability; Catechin; Chromatography, High Pressure Liquid; Injections, Intravenous; Male; Mouth Mucosa; Rats; Rats, Sprague-Dawley; Tea | 2000 |
Flavonoids apigenin and quercetin inhibit melanoma growth and metastatic potential.
Topics: Animals; Anticarcinogenic Agents; Apigenin; Catechin; Cell Division; Curcumin; Female; Flavonoids; Growth Inhibitors; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Neoplasm Transplantation; Quercetin; Resveratrol; Stilbenes; Tamoxifen; Tumor Cells, Cultured | 2000 |
Epigallocatechin gallate inhibits histamine release from rat basophilic leukemia (RBL-2H3) cells: role of tyrosine phosphorylation pathway.
Topics: Animals; Antineoplastic Agents; Catechin; Histamine Release; Leukemia, Basophilic, Acute; Leukemia, Experimental; Mast Cells; Phosphorylation; Rats; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 2000 |
Specific induction of glutathione S-transferase GSTM2 subunit expression by epigallocatechin gallate in rat liver.
Topics: Animals; Antineoplastic Agents; Catechin; Enzyme Induction; Gene Expression; Glutathione Transferase; Immunohistochemistry; In Vitro Techniques; Isoenzymes; Liver; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2000 |
Determination of catechins in human urine subsequent to tea ingestion by high-performance liquid chromatography with electrochemical detection.
Topics: Acetonitriles; Catechin; Chromatography, High Pressure Liquid; Electrochemistry; Flavonoids; Humans; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Phosphates; Tea; Time Factors | 2000 |
Epigallocatechin gallate increase the prostacyclin production of bovine aortic endothelial cells.
Topics: Animals; Arachidonic Acid; Catechin; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Eicosapentaenoic Acid; Endothelium, Vascular; Epoprostenol; Fibrinolytic Agents; Gallic Acid; Gas Chromatography-Mass Spectrometry; Molecular Structure; Platelet Aggregation Inhibitors; Thromboxanes | 2000 |
Differences of four catechins in cell cycle arrest and induction of apoptosis in LoVo cells.
Topics: Apoptosis; Catechin; Cell Cycle; Flavonoids; Humans; Tea; Tumor Cells, Cultured | 2000 |
Dermal toxicity of topical (-)epigallocatechin-3-gallate in BALB/c and SKH1 mice.
Topics: Administration, Cutaneous; Animals; Anticarcinogenic Agents; Catechin; Female; Mice; Mice, Inbred BALB C; Skin Diseases; Skin Tests; Tea | 2000 |
Inhibition of ultraviolet B-induced AP-1 activation by theaflavins from black tea.
Topics: Animals; Anticarcinogenic Agents; Biflavonoids; Caffeine; Catechin; Cell Line; Depression, Chemical; Enzyme Activation; Epidermal Cells; Epidermis; Gene Expression Regulation; Genes, Reporter; Luciferases; MAP Kinase Signaling System; Mice; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Tea; Transcription Factor AP-1; Transcription, Genetic; Transfection; Ultraviolet Rays | 2000 |
Cell cycle dysregulation by green tea polyphenol epigallocatechin-3-gallate.
Topics: Apoptosis; Catechin; Cell Cycle; Cell Cycle Proteins; Humans; Tea; Tumor Cells, Cultured | 2000 |
Preferential inhibition by (-)-epigallocatechin-3-gallate of the cell surface NADH oxidase and growth of transformed cells in culture.
Topics: Apoptosis; Catechin; Cell Division; Cell Line, Transformed; Cell Membrane; Enzyme Inhibitors; HeLa Cells; Humans; Membrane Proteins; Multienzyme Complexes; NADH, NADPH Oxidoreductases | 2000 |
Inhibition of arsenite-induced apoptosis and AP-1 activity by epigallocatechin-3-gallate and theaflavins.
Topics: Animals; Antimutagenic Agents; Antioxidants; Apoptosis; Arsenites; Biflavonoids; Catechin; Cells, Cultured; DNA; Drug Interactions; Flavonoids; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phenols; Phosphorylation; Polymers; Pyridines; Skin; Tea; Teratogens; Transcription Factor AP-1 | 2000 |
Protective effects of (-)-epigallocatechin gallate and (+)-catechin on paraquat-induced genotoxicity in cultured cells.
Topics: Animals; Antimutagenic Agents; Catechin; Cell Cycle; Cell Division; Cell Line; Cells, Cultured; Cricetinae; Cricetulus; Herbicides; Mutagenicity Tests; Mutagens; Paraquat; Reactive Oxygen Species | 2000 |
Antioxidant chemistry of green tea catechins. New oxidation products of (-)-epigallocatechin gallate and (-)-epigallocatechin from their reactions with peroxyl radicals.
Topics: Anticarcinogenic Agents; Antioxidants; Catechin; Chromatography, High Pressure Liquid; Flavonoids; Mass Spectrometry; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Peroxides; Tea | 2000 |
Identification of biliary metabolites of (-)-epigallocatechin gallate in rats.
Topics: Animals; Biliary Tract; Catechin; Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Rats; Rats, Wistar; Spectrometry, Mass, Fast Atom Bombardment | 2000 |
Suppression of adhesion and invasion of hepatoma cells in culture by tea compounds through antioxidative activity.
Topics: Animals; Antioxidants; Biflavonoids; Carcinoma, Hepatocellular; Catechin; Cell Adhesion; Dose-Response Relationship, Drug; Drug Synergism; Neoplasm Invasiveness; Reactive Oxygen Species; Tea; Tumor Cells, Cultured | 2000 |
Catechins delay lipid oxidation and alpha-tocopherol and beta-carotene depletion following ascorbate depletion in human plasma.
Topics: Ascorbic Acid; beta Carotene; Catechin; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Flavonoids; Humans; Kinetics; Lipid Peroxidation; Thiobarbituric Acid Reactive Substances; Vitamin E | 2000 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced NF-kappaB activation by tea polyphenols, (-)-epigallocatechin gallate and theaflavins.
Topics: Animals; Anticarcinogenic Agents; Biflavonoids; Carcinogens; Catechin; Cell Line; Cell Transformation, Neoplastic; DNA; Epidermis; Flavonoids; I-kappa B Proteins; Mice; NF-kappa B; Phenols; Phosphorylation; Polymers; Tea; Tetradecanoylphorbol Acetate; Transcriptional Activation | 2000 |
Antioxidative galloyl esters as enzyme inhibitors of p-hydroxybenzoate hydroxylase.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Amino Acid Sequence; Antioxidants; Catechin; Enzyme Inhibitors; Esters; Gallic Acid; Kinetics; Molecular Sequence Data; Molecular Structure; Parabens; Pseudomonas aeruginosa; Recombinant Proteins; Sequence Homology, Amino Acid | 2000 |
UVB-induced hemolysis of rat erythrocytes: protective effect of procyanidins from grape seeds.
Topics: Animals; Antioxidants; Biflavonoids; Catechin; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Erythrocyte Membrane; Erythrocytes; Glutathione; Hemoglobins; Hemolysis; Lipid Peroxidation; Male; Membrane Fluidity; Oxidants; Oxidation-Reduction; Phospholipids; Proanthocyanidins; Rats; Rats, Wistar; Rosales; Thiobarbituric Acid Reactive Substances; Ultraviolet Rays; Vitamin E | 2000 |
Effect of black and green tea polyphenols on c-jun phosphorylation and H(2)O(2) production in transformed and non-transformed human bronchial cell lines: possible mechanisms of cell growth inhibition and apoptosis induction.
Topics: Antioxidants; Apoptosis; Biflavonoids; Blotting, Western; Bronchi; Catechin; Cell Division; Cell Line, Transformed; Cell Survival; Cell Transformation, Viral; Epithelial Cells; Flavonoids; Gallic Acid; Genes, ras; Growth Inhibitors; Humans; Hydrogen Peroxide; Phenols; Phosphorylation; Polymers; Proto-Oncogene Proteins c-jun; Simian virus 40; Tea | 2000 |
Modulation of obesity by a green tea catechin.
Topics: Animals; Catechin; Female; Humans; Male; Obesity; Rats; Rats, Sprague-Dawley; Rats, Zucker; Tea | 2000 |
Comparative studies on the effects of green tea extracts and individual tea catechins on human CYP1A gene expression.
Topics: Animals; Carcinoma, Hepatocellular; Catechin; Cytochrome P-450 CYP1A1; DNA; Gene Expression; Guinea Pigs; Humans; Liver; Liver Neoplasms; Male; Mice; Plant Extracts; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; RNA, Messenger; Tea; Tumor Cells, Cultured | 2000 |
Apoptosis-inducing activity of lipid derivatives of gallic acid.
Topics: Apoptosis; Catechin; Cell Division; DNA Fragmentation; DNA, Neoplasm; Farnesol; Gallic Acid; Humans; Lipids; U937 Cells | 2000 |
Green tea polyphenols inhibit the sodium-dependent glucose transporter of intestinal epithelial cells by a competitive mechanism.
Topics: Animals; Biological Transport; Catechin; Flavonoids; Glucose; In Vitro Techniques; Intestinal Mucosa; Jejunum; Kinetics; Male; Microvilli; Monosaccharide Transport Proteins; Phenols; Polymers; Rabbits; Rats; Rats, Wistar; Tea | 2000 |
Inhibitory effects of tea catechins and O-methylated derivatives of (-)-epigallocatechin-3-O-gallate on mouse type IV allergy.
Topics: Administration, Topical; Animals; Catechin; Drug Hypersensitivity; Flavonoids; Male; Mice; Mice, Inbred ICR; Oxazolone; Phenols; Plant Leaves; Polymers; Species Specificity; Tea | 2000 |
Rapid microtiter assays for poxvirus topoisomerase, mammalian type IB topoisomerase and HIV-1 integrase: application to inhibitor isolation.
Topics: Animals; Antineoplastic Agents; Avidin; Base Sequence; Biotinylation; Catalysis; Catechin; DNA Topoisomerases, Type I; Drug Evaluation, Preclinical; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; HIV Integrase; HIV Integrase Inhibitors; HIV-1; Inhibitory Concentration 50; Molluscum contagiosum virus; Reproducibility of Results; Time Factors; Topoisomerase I Inhibitors | 2000 |
Is the cancer protective effect correlated with growth inhibitions by green tea (-)-epigallocatechin gallate mediated through an antioxidant mechanism?
Topics: Anticarcinogenic Agents; Antioxidants; Catechin; Cell Division; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Growth Inhibitors; HeLa Cells; Humans; Inhibitory Concentration 50; NAD; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Spectrophotometry, Ultraviolet | 2001 |
Detrimental effect of cancer preventive phytochemicals silymarin, genistein and epigallocatechin 3-gallate on epigenetic events in human prostate carcinoma DU145 cells.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Anticarcinogenic Agents; Catechin; Cell Cycle; Cell Death; Cell Division; ErbB Receptors; Genistein; Humans; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Plant Extracts; Prostatic Neoplasms; Protein Binding; Proteins; Shc Signaling Adaptor Proteins; Silymarin; Src Homology 2 Domain-Containing, Transforming Protein 1; Transforming Growth Factor alpha | 2001 |
Degradation of green tea catechins in tea drinks.
Topics: Beverages; Catechin; Drug Stability; Food Handling; Hydrogen-Ion Concentration; Tea; Temperature; Time Factors | 2001 |
Comparative efficacy as antioxidants between ascorbic acid and epigallocatechin gallate on cells of two human lymphoblastoid lines.
Topics: Antioxidants; Ascorbic Acid; Bleomycin; Catechin; Cell Line; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Lymphocytes; Mutagens | 2001 |
Green tea polyphenols as potent enhancers of glucocorticoid-induced mouse mammary tumor virus gene expression.
Topics: Animals; Antioxidants; Catechin; Cell Line; Dexamethasone; Drug Interactions; Enzyme Inhibitors; Esters; Fibroblasts; Flavonoids; Gallic Acid; Genes, Reporter; Glucocorticoids; Hydrolyzable Tannins; Luciferases; Mammary Tumor Virus, Mouse; Mice; Models, Chemical; Phenols; Plasmids; Polymers; Promoter Regions, Genetic; Rats; Tea; Transcription, Genetic; Transfection | 2001 |
Green tea polyphenol (-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress.
Topics: Adult; Catalase; Catechin; Female; Free Radical Scavengers; Glutathione; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Immunoenzyme Techniques; Leukocytes; Lipid Peroxidation; Male; Middle Aged; Nitric Oxide; Oxidative Stress; Radiodermatitis; Skin; Tea; Time Factors; Ultraviolet Rays | 2001 |
Combination cancer chemoprevention with green tea extract and sulindac shown in intestinal tumor formation in Min mice.
Topics: Adenocarcinoma; Animals; Catechin; Intestinal Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Plant Extracts; Sulindac; Tea | 2001 |
Role of antimutagens/anticarcinogens in cancer prevention.
Topics: Anticarcinogenic Agents; Antimutagenic Agents; Antioxidants; Catechin; Drug Resistance, Microbial; Escherichia coli; Histidine; Mutagenicity Tests; Mutation; Neoplasms; Salmonella typhimurium; Tea | 2000 |
Mechanisms of cancer prevention by tea polyphenols based on inhibition of TNF-alpha expression.
Topics: 3T3 Cells; Animals; Anticarcinogenic Agents; Catechin; Flavonoids; Gene Expression Regulation; Humans; Interleukin-1; Interleukin-10; Lung; Mice; Mice, Transgenic; Okadaic Acid; Phenols; Plant Extracts; Polymers; Recombinant Fusion Proteins; Tea; Tumor Necrosis Factor-alpha | 2000 |
Tea catechins and related polyphenols as anti-cancer agents.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Colonic Neoplasms; DNA Fragmentation; Flavonoids; Humans; Metalloendopeptidases; Phenols; Plant Extracts; Polymers; Stomach Neoplasms; Tea; Tumor Cells, Cultured; U937 Cells | 2000 |
Tumor gelatinases and invasion inhibited by the green tea flavanol epigallocatechin-3-gallate.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Blotting, Western; Catechin; Cell Division; Chemotaxis; Down-Regulation; Enzyme Inhibitors; Humans; Matrix Metalloproteinase Inhibitors; Neoplasm Invasiveness; Tea; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 2001 |
The effects of phenolic components of tea on the production of pro- and anti-inflammatory cytokines by human leukocytes in vitro.
Topics: Anti-Inflammatory Agents; Antioxidants; Catechin; Cell Division; Cells, Cultured; Cytokines; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Free Radicals; Humans; Interleukin-1; Interleukin-10; Interleukin-6; Leukocytes; Leukocytes, Mononuclear; Phenol; Phytotherapy; Tea; Tumor Necrosis Factor-alpha | 2001 |
Stereospecificity in membrane effects of catechins.
Topics: 1-Naphthylamine; 1,2-Dipalmitoylphosphatidylcholine; Anilino Naphthalenesulfonates; Catechin; Chromatography, High Pressure Liquid; Diphenylhexatriene; Flavonoids; Fluorescence Polarization; Fluorescent Dyes; Liposomes; Membrane Fluidity; Membranes, Artificial; Phosphatidylcholines; Stereoisomerism; Structure-Activity Relationship | 2001 |
Enantioselective synthesis of epigallocatechin-3-gallate (EGCG), the active polyphenol component from green tea.
Topics: Antineoplastic Agents, Phytogenic; Catechin; Oxidation-Reduction; Stereoisomerism; Tea | 2001 |
EGCG, a major component of green tea, inhibits tumour growth by inhibiting VEGF induction in human colon carcinoma cells.
Topics: Animals; Apoptosis; Catechin; Colonic Neoplasms; Endothelial Growth Factors; Enzyme Activation; Humans; Immunohistochemistry; Lymphokines; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Tea; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Synthesis of (-)-[4-3H]epigallocatechin gallate and its metabolic fate in rats after intravenous administration.
Topics: Animals; Anti-Infective Agents; Bile; Biotransformation; Catechin; Injections, Intravenous; Male; Radioisotope Dilution Technique; Rats; Rats, Wistar; Tea; Tritium | 2001 |
Synthesis of a 3,4,5-trimethoxybenzoyl ester analogue of epigallocatechin-3-gallate (EGCG): a potential route to the natural product green tea catechin, EGCG.
Topics: Catechin; Esters; Indicators and Reagents; Models, Molecular; Molecular Conformation; Molecular Structure; Structure-Activity Relationship; Tea | 2001 |
Ester bond-containing tea polyphenols potently inhibit proteasome activity in vitro and in vivo.
Topics: Calpain; Caspase 3; Caspases; Catechin; Cell Cycle Proteins; Cell Line, Transformed; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Esters; Fibroblasts; Flavonoids; Humans; I-kappa B Proteins; Jurkat Cells; Male; Microtubule-Associated Proteins; Models, Molecular; Molecular Conformation; Multienzyme Complexes; NF-KappaB Inhibitor alpha; Phenols; Polymers; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Structure-Activity Relationship; Tea; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2001 |
Apoptosis-inducing activity of high molecular weight fractions of tea extracts.
Topics: Apoptosis; Catechin; DNA Fragmentation; Humans; Molecular Weight; Neoplasms; Plant Extracts; Stomach Neoplasms; Tea; Tumor Cells, Cultured; U937 Cells | 2001 |
Inhibitory effect of epigallocatechin-gallate on brain tumor cell lines in vitro.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Apoptosis; Brain Neoplasms; Catechin; Glioblastoma; Glioma; Humans; Insulin-Like Growth Factor I; Pituitary Neoplasms; Rats; Tea; Tumor Cells, Cultured | 2001 |
Epigallocatechin gallate protects U937 cells against nitric oxide-induced cell cycle arrest and apoptosis.
Topics: Apoptosis; Biomarkers; Catechin; Cell Cycle; DNA; DNA Fragmentation; Free Radical Scavengers; G2 Phase; Humans; Mitosis; Nitric Oxide; Reactive Oxygen Species; U937 Cells | 2001 |
Evaluation of antioxidant activity of epigallocatechin gallate in biphasic model systems in vitro.
Topics: 2,2'-Dipyridyl; Amidines; Antioxidants; Catechin; Chelating Agents; Chromans; Copper; Humans; In Vitro Techniques; Indicators and Reagents; Lipid Peroxidation; Lipoproteins, LDL; Models, Biological; Oxidants; Oxidation-Reduction; Phenanthrolines; Phosphatidylcholines; Reference Values; Vitamin E | 2001 |
Anti-interferon gamma action of epigallocatechin-3-gallate mediated by specific inhibition of STAT1 activation.
Topics: Antineoplastic Agents; Catechin; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Immunoblotting; Interferon-gamma; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phosphorylation; Signal Transduction; STAT1 Transcription Factor; Trans-Activators; Tumor Cells, Cultured | 2001 |
Legionella pneumophila replication in macrophages inhibited by selective immunomodulatory effects on cytokine formation by epigallocatechin gallate, a major form of tea catechins.
Topics: Animals; Catechin; Cytokines; Humans; Legionella pneumophila; Legionnaires' Disease; Macrophages, Alveolar; Mice; Tea | 2001 |
Mechanism of synergy between epigallocatechin gallate and beta-lactams against methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; beta-Lactams; Catechin; Cell Wall; Drug Synergism; Methicillin Resistance; Microbial Sensitivity Tests; Peptidoglycan; Staphylococcus aureus | 2001 |
Green tea polyphenol (-)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes, depletion of antigen-presenting cells, and oxidative stress.
Topics: Animals; Antigen-Presenting Cells; Antioxidants; Catechin; Female; Flavonoids; Hydrogen Peroxide; Leukocytes; Mice; Mice, Inbred C3H; Neutrophil Infiltration; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Phenols; Polymers; Skin; Tea; Ultraviolet Rays | 2001 |
The role of inducible-nitric oxide in cocaine-induced kindling.
Topics: Animals; Catechin; Cocaine; Convulsants; Hippocampus; Kindling, Neurologic; Lysine; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures | 2001 |
Green tea polyphenols: novel irreversible inhibitors of dopa decarboxylase.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Binding Sites; Catechin; Chromatography, High Pressure Liquid; Circular Dichroism; Dopa Decarboxylase; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Kidney; Spectrophotometry; Swine; Tea | 2001 |
Black tea is a powerful chemopreventor of reactive oxygen and nitrogen species: comparison with its individual catechin constituents and green tea.
Topics: Animals; Biflavonoids; Catechin; Cells, Cultured; Chemoprevention; Enzyme Induction; Fermentation; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Reactive Oxygen Species; RNA, Messenger; Tea | 2001 |
Potent antimutagenic activity of white tea in comparison with green tea in the Salmonella assay.
Topics: Animals; Antimutagenic Agents; Catechin; Chromatography, High Pressure Liquid; Cooking; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Imidazoles; Microsomes, Liver; Mutagenicity Tests; Mutagens; Oxidoreductases; Quinolines; Quinoxalines; Rats; Salmonella typhimurium; Tea | 2001 |
Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450.
Topics: Aflatoxin B1; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Beverages; Carcinogens; Catechin; Cell Membrane; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Kinetics; Mixed Function Oxygenases; Mutagenesis; NADPH-Ferrihemoprotein Reductase; Protein Binding; Salmonella typhimurium | 2001 |
Apoptosis induction by epigallocatechin gallate involves its binding to Fas.
Topics: Apoptosis; Blotting, Western; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Catechin; Chromatography, Affinity; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Enzyme Activation; fas Receptor; Flow Cytometry; Humans; Protein Binding; U937 Cells | 2001 |
Green tea extracts decrease carcinogen-induced mammary tumor burden in rats and rate of breast cancer cell proliferation in culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Catechin; Cell Cycle Proteins; Cell Death; Cell Division; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Female; Flavonoids; Flow Cytometry; Mammary Neoplasms, Animal; Phenols; Plant Extracts; Polymers; Probability; Rats; Tea; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2001 |
Inhibitory effects of purified green tea epicatechins on contraction and proliferation of arterial smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Catechin; Cell Division; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Tea; Vasodilator Agents | 2000 |
The molecular interaction of human salivary histatins with polyphenolic compounds.
Topics: Amino Acid Sequence; Catechin; Humans; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Proteins; Ultracentrifugation | 2001 |
Tea catechin, (-)-epigallocatechin gallate, causes membrane depolarizations of myenteric neurons in the guinea-pig small intestine.
Topics: Action Potentials; Animals; Catechin; Dose-Response Relationship, Drug; Electrophysiology; Free Radical Scavengers; Guinea Pigs; In Vitro Techniques; Intestine, Small; Male; Myenteric Plexus; Neurons; Tea | 2001 |
The green tea polyphenol (-)-epigallocatechin-3-gallate blocks nuclear factor-kappa B activation by inhibiting I kappa B kinase activity in the intestinal epithelial cell line IEC-6.
Topics: Animals; Catechin; Cell-Free System; Cells, Cultured; Enzyme Inhibitors; Flavonoids; I-kappa B Kinase; I-kappa B Proteins; Intestinal Mucosa; NF-kappa B; Phenols; Phosphorylation; Polymers; Protein Serine-Threonine Kinases; Rats; Tea; Tumor Necrosis Factor-alpha | 2001 |
Reduction of spontaneous mutagenesis in mismatch repair-deficient and proficient cells by dietary antioxidants.
Topics: Antioxidants; Ascorbic Acid; Base Pair Mismatch; Blood Proteins; Carotenoids; Catechin; Cell Line; Cell Survival; Chromosomes, Human, Pair 3; Clone Cells; Dietary Supplements; DNA Repair; Humans; Lycopene; Mutagenesis; Mutagenicity Tests; Vitamin E | 2001 |
Modulation of gene expression by (-)-epigallocatechin gallate in PC-9 cells using a cDNA expression array.
Topics: Antimutagenic Agents; Catechin; DNA Probes; DNA, Complementary; Down-Regulation; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; NF-kappa B; Oligonucleotide Array Sequence Analysis; Poly A; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Up-Regulation | 2001 |
Mechanisms of inhibition of the Ras-MAP kinase signaling pathway in 30.7b Ras 12 cells by tea polyphenols (-)-epigallocatechin-3-gallate and theaflavin-3,3'-digallate.
Topics: Adenosine Triphosphate; Biflavonoids; Catalysis; Catechin; Cell Line; DNA-Binding Proteins; ets-Domain Protein Elk-1; Flavonoids; Gallic Acid; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phenols; Phosphorylation; Polymers; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Signal Transduction; Substrate Specificity; Tea; Transcription Factors | 2001 |
Metabolic fate of (-)-[4-(3)H]epigallocatechin gallate in rats after oral administration.
Topics: Administration, Oral; Animals; Catechin; Feces; Male; Radioisotope Dilution Technique; Rats; Rats, Wistar; Tea; Urine | 2001 |
Antioxidant activity and inhibitory effect of Gamazumi (Viburnum dilatatum THUNB.) on oxidative damage induced by water immersion restraint stress in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Amylases; Animals; Anti-Ulcer Agents; Antioxidants; Aspartate Aminotransferases; Catechin; Creatine Kinase; Electron Spin Resonance Spectroscopy; Fruit; Immersion; L-Lactate Dehydrogenase; Lipid Peroxides; Male; Rats; Stomach Ulcer; Stress, Physiological | 2001 |
Involvement of ERK and protein tyrosine phosphatase signaling pathways in EGCG-induced cyclooxygenase-2 expression in Raw 264.7 cells.
Topics: Animals; Catechin; Cell Line; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Flavonoids; Isoenzymes; Macrophages; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Protein Tyrosine Phosphatases; RNA, Messenger; Signal Transduction; Up-Regulation; Vanadates | 2001 |
The 'pivotal antioxidant' hypothesis for the role of flavonoids in their reduction of HO* radical-induced damage on DNA.
Topics: Antioxidants; Ascorbic Acid; Catechin; Chromans; DNA Damage; DNA, Bacterial; Flavonoids; Gamma Rays; Glutathione; Hydroxyl Radical; Models, Biological; Oxidants; Oxidation-Reduction | 2001 |
Epigallocatechin gallate synergy with ampicillin/sulbactam against 28 clinical isolates of methicillin-resistant Staphylococcus aureus.
Topics: Ampicillin; Anti-Bacterial Agents; Catechin; Drug Synergism; Humans; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus aureus; Sulbactam; Time Factors | 2001 |
Prolyl endopeptidase inhibitors from green tea.
Topics: Camellia sinensis; Catechin; Kinetics; Magnetic Resonance Spectroscopy; Plant Extracts; Prolyl Oligopeptidases; Protease Inhibitors; Serine Endopeptidases; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Ultraviolet | 2001 |
Green tea polyphenol (-)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurodegeneration.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Catalase; Catechin; Dopamine; Dopamine Agents; Flavonoids; Free Radical Scavengers; Immunohistochemistry; Mice; Mice, Inbred C57BL; Monoamine Oxidase; MPTP Poisoning; Nerve Degeneration; Neurons; Oxidative Stress; Phenols; Polymers; Rats; Superoxide Dismutase; Tea; Tyrosine 3-Monooxygenase | 2001 |
Epigallocatechin gallate (EGCG) inhibits the sulfation of 1-naphthol in a human colon carcinoma cell line, Caco-2.
Topics: Antineoplastic Agents; Arylsulfotransferase; Caco-2 Cells; Catechin; Chromatography, High Pressure Liquid; Depression, Chemical; Enzyme Inhibitors; Humans; Naphthols; Sulfates | 2001 |
Inhibitory activities of (-)-epigallocatechin-3-O-gallate against topoisomerases I and II.
Topics: Animals; Catechin; Cattle; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Superhelical; Enzyme Inhibitors; Humans; Structure-Activity Relationship; Tea; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 2001 |
Inhibitory effect of epigallocatechin gallate on adhesion of murine melanoma cells to laminin.
Topics: Animals; Antineoplastic Agents; Catechin; Cell Adhesion; Chromatography, Affinity; Collagen; Laminin; Melanoma, Experimental; Mice; Neoplasm Metastasis; Vitronectin | 2001 |
Effects of (-)-epigallocatechin-3-gallate, the main component of green tea, on the cloned rat brain Kv1.5 potassium channels.
Topics: Animals; Anticarcinogenic Agents; Catechin; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Ion Transport; Kinetics; Kv1.5 Potassium Channel; Potassium Channels; Potassium Channels, Voltage-Gated; Rats; Tea | 2001 |
Simplified catechin-gallate inhibitors of HIV-1 reverse transcriptase.
Topics: Catechin; HIV Reverse Transcriptase; Mutation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2001 |
Green tea constituent (--)-epigallocatechin-3-gallate inhibits topoisomerase I activity in human colon carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Catechin; Cell Division; Colonic Neoplasms; DNA Topoisomerases, Type II; Enzyme Inhibitors; Humans; Tea; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 2001 |
Inhibition of UVB-induced oxidative stress-mediated phosphorylation of mitogen-activated protein kinase signaling pathways in cultured human epidermal keratinocytes by green tea polyphenol (-)-epigallocatechin-3-gallate.
Topics: Antioxidants; Ascorbic Acid; Blotting, Western; Catechin; Epidermal Cells; Epidermis; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Keratinocytes; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Oxidants; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Ultraviolet Rays | 2001 |
Inhibitory effects of (-)-epigallocatechin gallate on the life cycle of human immunodeficiency virus type 1 (HIV-1).
Topics: Anti-HIV Agents; Catechin; Cell Line; HIV Protease; HIV Reverse Transcriptase; HIV-1; Humans; Monocytes; RNA, Messenger; RNA, Viral; T-Lymphocytes; Tea; Virion | 2002 |
A novel method of measuring hydroxyl radical-scavenging activity of antioxidants using gamma-irradiation.
Topics: Antioxidants; Catechin; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Gamma Rays; Hydroxyl Radical; Spin Labels; Spin Trapping | 2001 |
Green tea polyphenol stimulates a Ras, MEKK1, MEK3, and p38 cascade to increase activator protein 1 factor-dependent involucrin gene expression in normal human keratinocytes.
Topics: Catechin; Cells, Cultured; Gene Expression Regulation; Humans; Keratinocytes; MAP Kinase Kinase 3; MAP Kinase Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Protein Precursors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; ras Proteins; Tea; Transcription Factor AP-1 | 2002 |
Green tea epigallocatechin gallate: a natural inhibitor of fatty-acid synthase.
Topics: 4-Butyrolactone; Acyltransferases; Animals; Binding, Competitive; Catechin; Chickens; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Acid Synthase, Type I; Kinetics; Multienzyme Complexes; NADP; Tea | 2001 |
Liquid chromatography with multi-channel electrochemical detection for the determination of epigallocatechin gallate in rat plasma utilizing an automated blood sampling device.
Topics: Animals; Catechin; Chromatography, Liquid; Electrochemistry; Rats; Reproducibility of Results; Sensitivity and Specificity | 2001 |
Inhibition of melanoma growth and metastasis by combination with (-)-epigallocatechin-3-gallate and dacarbazine in mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Catechin; Cell Aggregation; Cell Communication; Cell Movement; Cell Transformation, Neoplastic; Dacarbazine; Drug Screening Assays, Antitumor; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Growth Inhibitors; Injections, Intraperitoneal; Lung Neoplasms; Male; Matrix Metalloproteinases; Melanoma, Experimental; Mice; Neoplasm Transplantation; Phosphorylation; Protein-Tyrosine Kinases; Survival Rate; Tea; Tumor Cells, Cultured; Tumor Stem Cell Assay; Tyrosine | 2001 |
Potentiometric and (1)H NMR studies of complexation of Al(3+) with (-)-epigallocatechin gallate, a major active constituent of green tea.
Topics: Aluminum; Antineoplastic Agents; Catechin; Electrochemistry; Ligands; Nuclear Magnetic Resonance, Biomolecular; Organometallic Compounds; Tea; Titrimetry | 2002 |
Effects of epigallocatechin-3-gallate on growth, epidermal growth factor receptor signaling pathways, gene expression, and chemosensitivity in human head and neck squamous cell carcinoma cell lines.
Topics: Antineoplastic Agents; Catechin; Cell Division; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; Signal Transduction | 2001 |
Differential responses of skin cancer-chemopreventive agents silibinin, quercetin, and epigallocatechin 3-gallate on mitogenic signaling and cell cycle regulators in human epidermoid carcinoma A431 cells.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Anticarcinogenic Agents; Apoptosis; Carcinoma, Squamous Cell; Catechin; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Enzyme Inhibitors; ErbB Receptors; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitogens; Phosphorylation; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Quercetin; Shc Signaling Adaptor Proteins; Signal Transduction; Silymarin; Skin Neoplasms; Src Homology 2 Domain-Containing, Transforming Protein 1; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2001 |
Rapid conversion of tea catechins to monomethylated products by rat liver cytosolic catechol-O-methyltransferase.
Topics: Animals; Catechin; Catechol O-Methyltransferase; Cytosol; Female; Flavonoids; Hydrogen-Ion Concentration; Kinetics; Liver; Mass Spectrometry; Methylation; Phenols; Polymers; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; Tea | 2001 |
(-)Epigallocatechin-3-gallate inhibits leukocyte elastase: potential of the phyto-factor in hindering inflammation, emphysema, and invasion.
Topics: Catechin; Cathepsin G; Cathepsins; Cells, Cultured; Dose-Response Relationship, Drug; Emphysema; Enzyme Activation; Enzyme Inhibitors; Gelatinases; Humans; Inflammation; Leukocyte Elastase; Neutrophils; Phytotherapy; Serine Endopeptidases; Thrombin | 2002 |
Preformulation study of epigallocatechin gallate, a promising antioxidant for topical skin cancer prevention.
Topics: Administration, Topical; Antineoplastic Agents, Phytogenic; Antioxidants; Catechin; Chemistry, Pharmaceutical; Drug Evaluation, Preclinical; Drug Stability; Ethylene Glycols; Glycerol; Osmolar Concentration; Skin Neoplasms; Solvents | 2002 |
Epigallocatechin-3-gallate inhibits basic fibroblast growth factor-induced intracellular signaling transduction pathway in rat aortic smooth muscle cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Aorta, Thoracic; Blotting, Western; Catechin; Cell Division; Cell Movement; Cells, Cultured; Down-Regulation; Fibroblast Growth Factor 2; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Muscle, Smooth; Protein Kinase C; ras Proteins; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2002 |
Epigallocatechin gallate synergistically enhances the activity of carbapenems against methicillin-resistant Staphylococcus aureus.
Topics: Antioxidants; Carbapenems; Catechin; Colony-Forming Units Assay; Drug Synergism; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus aureus; Thienamycins | 2002 |
In vitro therapeutic effect of epigallocatechin gallate on nicotine-induced impairment of resistance to Legionella pneumophila infection of established MH-S alveolar macrophages.
Topics: Animals; Catechin; Cell Line; Cytokines; Interferon-gamma; Legionella pneumophila; Macrophages, Alveolar; Mice; Nicotine; Tea; Tumor Necrosis Factor-alpha | 2002 |
Synergistic effects of (-)-epigallocatechin gallate with sulindac against colon carcinogenesis of rats treated with azoxymethane.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azoxymethane; Carcinogens; Catechin; Choristoma; Colon; Colonic Neoplasms; Drug Synergism; In Situ Nick-End Labeling; Incidence; Male; Nucleolus Organizer Region; Precancerous Conditions; Rats; Rats, Inbred F344; Sulindac; Tea | 2002 |
Green tea catechins inhibit vascular endothelial growth factor receptor phosphorylation.
Topics: Angiogenesis Inhibitors; Animals; Beverages; Catechin; Cattle; Cells, Cultured; Chick Embryo; Endothelium, Vascular; Humans; Kinetics; Neovascularization, Physiologic; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor | 2002 |
Inhibition by epigallocatechin gallate (EGCg) of conjugative R plasmid transfer in Escherichia coli.
Topics: Catechin; Conjugation, Genetic; DNA, Bacterial; Escherichia coli; Plasmids | 2001 |
The green tea polyphenol (-)-epigallocatechin gallate attenuates beta-amyloid-induced neurotoxicity in cultured hippocampal neurons.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Blotting, Western; Caspase 3; Caspases; Catechin; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Drug Antagonism; Fetus; Hippocampus; Isoenzymes; Malondialdehyde; Membrane Proteins; Neurons; Neuroprotective Agents; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Suppressor Protein p53 | 2001 |
Role of the retinoblastoma (pRb)-E2F/DP pathway in cancer chemopreventive effects of green tea polyphenol epigallocatechin-3-gallate.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Cycle; Cell Cycle Proteins; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; Humans; Phosphorylation; Retinoblastoma; Retinoblastoma Protein; Tea; Transcription Factors; Tumor Cells, Cultured | 2002 |
Chemical studies of proanthocyanidins and hydrolyzable tannins.
Topics: Anthocyanins; Antioxidants; Catechin; Dimerization; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydrolysis; Hydrolyzable Tannins; Hydroxyl Radical; Magnetic Resonance Spectroscopy; Models, Chemical; Oxygen; Phenol; Proanthocyanidins; Tannins; Time Factors | 2001 |
Antioxidant ability of various flavonoids against DPPH radicals and LDL oxidation.
Topics: Antioxidants; Arteriosclerosis; Biphenyl Compounds; Catechin; Dose-Response Relationship, Drug; Flavonoids; Free Radical Scavengers; Humans; In Vitro Techniques; Indicators and Reagents; Lipoproteins, LDL; Oxidation-Reduction; Phenols; Picrates; Polymers | 2001 |
EGCG attenuates AMPA-induced intracellular calcium increase in hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Catechin; Cations, Divalent; Cell Survival; Cells, Cultured; Hippocampus; Hydrogen Peroxide; Intracellular Fluid; Lipid Peroxidation; Malondialdehyde; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Time Factors | 2002 |
Tea catechin, (-)-epigallocatechin gallate, facilitates cholinergic ganglion transmission in the myenteric plexus of the guinea-pig small intestine.
Topics: Acetylcholine; Action Potentials; Animals; Camellia sinensis; Catechin; Drugs, Chinese Herbal; Excitatory Postsynaptic Potentials; Guinea Pigs; Intestine, Small; Male; Myenteric Plexus; Neurons; Neuroprotective Agents; Presynaptic Terminals; Synaptic Transmission | 2002 |
Green tea polyphenol epigallocatechin-3 gallate inhibits Her-2/neu signaling, proliferation, and transformed phenotype of breast cancer cells.
Topics: Animals; Anticarcinogenic Agents; Beverages; Catechin; Cell Division; Cell Transformation, Neoplastic; Female; Growth Inhibitors; Mammary Neoplasms, Experimental; Mice; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2; Signal Transduction | 2002 |
Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Camellia sinensis; Catechin; Cell Division; CHO Cells; Cricetinae; Drug Resistance, Multiple; Flavonoids; Humans; Phenols; Polymers; Protein Binding; Rhodamine 123; Vinblastine | 2002 |
Green tea polyphenol (-)-epigallocatechin 3-gallate inhibits MMP-2 secretion and MT1-MMP-driven migration in glioblastoma cells.
Topics: Animals; Antineoplastic Agents; Camellia sinensis; Catechin; Cell Movement; COS Cells; Culture Media, Conditioned; Enzyme Inhibitors; Enzyme Precursors; Flavonoids; Gelatin; Gelatinases; Glioblastoma; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Phenols; Polymers; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2002 |
Kinetic analysis and mechanistic aspects of autoxidation of catechins.
Topics: Antioxidants; Benzoquinones; Borates; Catechin; Cations, Divalent; Copper; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydrogen-Ion Concentration; Models, Chemical; Oxidation-Reduction; Oxygen; Quality Control | 2002 |
[Effects of different catechins on cell cycle arrest and induction of apoptosis in LoVo cells].
Topics: Apoptosis; Catechin; Cell Cycle; Cell Line, Tumor; Flow Cytometry; Humans | 2000 |
Fenton reaction is primarily involved in a mechanism of (-)-epigallocatechin-3-gallate to induce osteoclastic cell death.
Topics: Animals; Animals, Newborn; Apoptosis; Caspase 3; Caspases; Catechin; Cell Division; Cells, Cultured; DNA Damage; Dose-Response Relationship, Drug; Ferrous Compounds; Hydrogen Peroxide; Male; Mice; Microscopy, Fluorescence; Models, Chemical; Osteoclasts | 2002 |
Evaluation of the antigenotoxic potential of monomeric and dimeric flavanols, and black tea polyphenols against heterocyclic amine-induced DNA damage in human lymphocytes using the Comet assay.
Topics: Antimutagenic Agents; Biflavonoids; Carbolines; Carcinogens; Catechin; Cell Survival; Comet Assay; DNA Damage; Flavonoids; Humans; Lymphocytes; Mutagenicity Tests; Mutagens; Phenols; Polymers; Tea | 2002 |
Polyphenolic antioxidant (-)-epigallocatechin-3-gallate from green tea as a candidate anti-HIV agent.
Topics: Anti-HIV Agents; Antioxidants; Catechin; HIV Reverse Transcriptase; Humans; In Vitro Techniques; Monocytes; Tea | 2002 |
Antitumor activity of compounds isolated from leaves of Eriobotrya japonica.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Antineoplastic Agents; Biflavonoids; Carcinogens; Catechin; Female; Glucosides; Herpesvirus 4, Human; Humans; Mice; Mice, Inbred ICR; Nasopharyngeal Neoplasms; Norisoprenoids; Peroxynitrous Acid; Plant Leaves; Proanthocyanidins; Rosaceae; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate; Virus Activation | 2002 |
Protective activity of green tea against free radical- and glucose-mediated protein damage.
Topics: Amidines; Antioxidants; Catechin; Free Radicals; Glucose; Glycation End Products, Advanced; Glycosylation; Hydrolyzable Tannins; Oxidants; Oxidation-Reduction; Plant Extracts; Proteins; Tea | 2002 |
Structure-activity relationships for inhibition of human 5alpha-reductases by polyphenols.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Catechin; Cell Extracts; Cell-Free System; Enzyme Inhibitors; Flavonoids; Humans; Kinetics; Phenols; Polymers; Rats; Structure-Activity Relationship; Tea | 2002 |
Green tea catechins decrease apolipoprotein B-100 secretion from HepG2 cells.
Topics: Anticholesteremic Agents; Apolipoprotein B-100; Apolipoproteins B; Catechin; Cholesterol, VLDL; Cysteine Endopeptidases; Humans; Hydroxycholesterols; Lipids; Multienzyme Complexes; Proteasome Endopeptidase Complex; Tea; Tumor Cells, Cultured | 2002 |
Differential regulation of neutrophil phospholipase d activity and degranulation.
Topics: Catechin; Cell Degranulation; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Genistein; Glucuronidase; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Phosphatidic Acids; Phospholipase D; Resveratrol; Signal Transduction; Stilbenes; Tetradecanoylphorbol Acetate | 2002 |
A rapid screening assay for antioxidant potential of natural and synthetic agents in vitro.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Antineoplastic Agents, Phytogenic; Antioxidants; Biological Assay; Catechin; Copper; Deoxyguanosine; DNA Damage; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Ellagic Acid; Free Radical Scavengers; Humans; Oxygen; Reactive Oxygen Species | 2002 |
Green tea and its catechins inhibit breast cancer xenografts.
Topics: Animals; Breast Neoplasms; Catechin; Cell Division; Cells, Cultured; Endothelium, Vascular; Humans; Mice; Mice, SCID; Plant Extracts; Tea; Transplantation, Heterologous; Umbilical Veins | 2001 |
Kinetics of reduction of ferrylmyoglobin by (-)-epigallocatechin gallate and green tea extract.
Topics: Catechin; Hydrogen-Ion Concentration; Kinetics; Metmyoglobin; Oxidation-Reduction; Plant Extracts; Tea; Thermodynamics | 2002 |
Effects of dietary antioxidants on human DNA ex vivo.
Topics: alpha-Tocopherol; Antioxidants; Ascorbic Acid; Caffeic Acids; Catechin; Cells, Cultured; Comet Assay; DNA; DNA Damage; Dose-Response Relationship, Drug; Female; Free Radical Scavengers; Humans; Hydrogen Peroxide; Lymphocytes; Male; Oxidative Stress; Quercetin; Time Factors | 2002 |
Effect of particle size in preparative reversed-phase high-performance liquid chromatography on the isolation of epigallocatechin gallate from Korean green tea.
Topics: Catechin; Chromatography, High Pressure Liquid; Particle Size; Spectrophotometry, Ultraviolet; Tea | 2002 |
Lung cancer prevention with (-)-epigallocatechin gallate using monitoring by heterogeneous nuclear ribonucleoprotein B1.
Topics: Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Catechin; Cell Cycle; Gene Expression Regulation; Genistein; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Heterogeneous-Nuclear Ribonucleoproteins; Humans; Lung Neoplasms; Ribonucleoproteins; RNA, Messenger; Tea; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
Kinetic analysis of the effect of (-)-epigallocatechin gallate on the DNA scission induced by Fe(II).
Topics: Antimutagenic Agents; Catechin; Citric Acid; DNA, Bacterial; Escherichia coli; Ferrous Compounds; Kinetics; Nucleic Acid Conformation; Plasmids | 2002 |
Inhibition of the PDGF beta-receptor tyrosine phosphorylation and its downstream intracellular signal transduction pathway in rat and human vascular smooth muscle cells by different catechins.
Topics: Animals; Aorta; Becaplermin; Bromodeoxyuridine; Calcium; Carotid Artery Injuries; Catechin; Cell Count; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Humans; Male; Muscle, Smooth, Vascular; Phosphorylation; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Inbred WKY; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Tunica Intima; Tunica Media; Tyrosine | 2002 |
[Novel molecular therapy for acute promyelocytic leukemia (APL): application of the green tea component, catechin].
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Catechin; Humans; Leukemia, Prolymphocytic; Mice; Oligonucleotide Array Sequence Analysis; Tea; Tumor Cells, Cultured | 2002 |
Protective effect of green tea against lipid peroxidation in the rat liver, blood serum and the brain.
Topics: Animals; Antioxidants; Brain; Camellia sinensis; Catechin; Lipid Peroxidation; Liver; Male; Phytotherapy; Plant Extracts; Rats; Rats, Wistar | 2002 |
Inhibitory effect of epigallocatechin-3-gallate on growth and invasion in human biliary tract carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Bile Duct Neoplasms; Catechin; Cell Division; Drug Screening Assays, Antitumor; Humans; Neoplasm Invasiveness; Tumor Cells, Cultured | 2002 |
Green tea constituent epigallocatechin-3-gallate inhibits angiogenic differentiation of human endothelial cells.
Topics: Animals; Catechin; Cell Differentiation; Cell Division; Cell Movement; Cells, Cultured; Endothelium, Vascular; Humans; Matrix Metalloproteinase Inhibitors; Neovascularization, Physiologic; Protease Inhibitors; Tea | 2002 |
Involvement of protein kinase C activation and cell survival/ cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action.
Topics: bcl-2-Associated X Protein; Catechin; Cell Cycle; Cell Survival; Cells, Cultured; Enzyme Activation; Mitogen-Activated Protein Kinases; Neuroprotective Agents; Oxidopamine; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Tea | 2002 |
Anhydrous Carbopol polymer gels for the topical delivery of oxygen/water sensitive compounds.
Topics: Acrylic Resins; Catechin; Chemistry, Pharmaceutical; Drug Delivery Systems; Drug Stability; Gels; Glycerol; Oxygen; Polyvinyls; Viscosity; Water | 2002 |
Inhibition of penicillinase by epigallocatechin gallate resulting in restoration of antibacterial activity of penicillin against penicillinase-producing Staphylococcus aureus.
Topics: beta-Lactamase Inhibitors; Catechin; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Microbial Sensitivity Tests; Penicillins; Staphylococcus aureus | 2002 |
Flavonoids exert diverse inhibitory effects on the activation of NF-kappaB.
Topics: Animals; Antioxidants; Catechin; Cell Hypoxia; Flavonoids; Genistein; Interleukin-1; L Cells; Mice; NF-kappa B; Quercetin | 2002 |
Mechanisms of 2-butoxyethanol carcinogenicity: studies on Syrian Hamster Embryo (SHE) cell transformation.
Topics: Animals; Antioxidants; Catechin; Cell Transformation, Neoplastic; Cells, Cultured; Comet Assay; Cricetinae; DNA Damage; Dose-Response Relationship, Drug; Drug Antagonism; Drug Combinations; Ethylene Glycols; Female; Ferrous Compounds; Glycolates; Mesocricetus; Mutagens; Pregnancy; Solvents; Vitamin E | 2002 |
Effects of tea components on the response of GABA(A) receptors expressed in Xenopus Oocytes.
Topics: Acyclic Monoterpenes; Animals; Catechin; Drug Synergism; Female; gamma-Aminobutyric Acid; Gene Expression; Membrane Potentials; Monoterpenes; Oocytes; Plant Extracts; Receptors, GABA-A; Recombinant Proteins; RNA, Complementary; Tea; Terpenes; Transfection; Xenopus laevis | 2002 |
Flavonoids uptake and their effect on cell cycle of human colon adenocarcinoma cells (Caco2).
Topics: Adenocarcinoma; Anticarcinogenic Agents; Antioxidants; Catechin; Cell Cycle; Cell Division; Colonic Neoplasms; Flavonoids; Gallic Acid; Humans; Hydrogen Peroxide; Molecular Structure; Quercetin; Structure-Activity Relationship; Tea; Tumor Cells, Cultured | 2002 |
Epigallocatechin gallate, a potential immunomodulatory agent of tea components, diminishes cigarette smoke condensate-induced suppression of anti-Legionella pneumophila activity and cytokine responses of alveolar macrophages.
Topics: Adjuvants, Immunologic; Animals; Catechin; Cell Line; Cytokines; Dose-Response Relationship, Drug; Immune Tolerance; Immunity, Cellular; Legionella pneumophila; Legionnaires' Disease; Macrophages, Alveolar; Mice; Nicotiana; Plant Extracts; Smoke | 2002 |
Effect of (-)-epigallocatechin-3-gallate on respiratory burst of rat macrophages.
Topics: Animals; Antioxidants; Catechin; Cells, Cultured; Macrophages, Peritoneal; Male; Rats; Rats, Wistar; Reactive Oxygen Species; Respiratory Burst | 2002 |
Diet and breast cancer.
Topics: Animals; Breast Neoplasms; Catechin; Cattle; Coumaric Acids; Cyclohexenes; Dehydroepiandrosterone; Diet; Female; Genistein; Humans; Indoles; Isothiocyanates; Limonene; Milk; Terpenes | 2002 |
Physiological concentrations of (-)-epigallocatechin-3-O-gallate (EGCg) prevent chromosomal damage induced by reactive oxygen species in WIL2-NS cells.
Topics: Antimutagenic Agents; Catechin; Cell Line; Chromosome Breakage; Chromosomes; Humans; Hydrogen Peroxide; Osmolar Concentration; Oxidants; Reactive Oxygen Species; Superoxides; tert-Butylhydroperoxide | 2002 |
Study of non-covalent complexation between catechin derivatives and peptides by electrospray ionization mass spectrometry.
Topics: Amino Acid Sequence; Catechin; Dimerization; Food Analysis; Macromolecular Substances; Molecular Sequence Data; Peptide Fragments; Peptides; Proline-Rich Protein Domains; Solutions; Spectrometry, Mass, Electrospray Ionization | 2002 |
Epigallocatechin gallate, a constituent of green tea, represses hepatic glucose production.
Topics: Acetylcysteine; Animals; Catechin; Gene Expression Regulation, Enzymologic; Gluconeogenesis; Glucose; Glucose-6-Phosphatase; Insulin; Liver; Liver Neoplasms, Experimental; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Signal Transduction; Superoxide Dismutase; Tumor Cells, Cultured; Tyrosine | 2002 |
Suppression of human pancreatic carcinoma cell growth and invasion by epigallocatechin-3-gallate.
Topics: Antineoplastic Agents, Phytogenic; Biocompatible Materials; Carcinoma; Catechin; Cell Division; Collagen; Cyclin D1; Drug Combinations; Humans; Laminin; Neoplasm Invasiveness; Pancreatic Neoplasms; Proteoglycans; Tea; Tumor Cells, Cultured | 2002 |
Changes in ceramide levels upon catechins-induced apoptosis in LoVo cells.
Topics: Apoptosis; Catechin; Ceramides; Colonic Neoplasms; Diacylglycerol Kinase; Humans; Kinetics; Tumor Cells, Cultured | 2002 |
Hydrogen peroxide generation in caco-2 cell culture medium by addition of phenolic compounds: effect of ascorbic acid.
Topics: Antioxidants; Ascorbic Acid; Caco-2 Cells; Catechin; Culture Media; Humans; Hydrogen Peroxide; Vitis | 2002 |
Prevention of carcinogenesis of mouse mammary epithelial cells RIII/MG by epigallocatechin gallate.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Catechin; DNA Fragmentation; Dose-Response Relationship, Drug; Epithelial Cells; Female; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Time Factors; Tumor Cells, Cultured | 2002 |
Inhibition of fibroblast growth factors by green tea.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Breast Neoplasms; Catechin; Cells, Cultured; Endothelium, Vascular; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Humans; Neovascularization, Pathologic; Plant Extracts; RNA, Messenger; Tea | 2002 |
Effects of epigallocatechin 3-O-gallate on cellular antioxidative system in HepG2 cells.
Topics: alpha-Tocopherol; Animals; Antioxidants; Catechin; Culture Media, Serum-Free; Glutathione; Glutathione Peroxidase; Humans; Lipid Peroxidation; Lipid Peroxides; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Tumor Cells, Cultured | 2002 |
Multiple conformations of the proline-rich protein/epigallocatechin gallate complex determined by time-averaged nuclear Overhauser effects.
Topics: Amino Acid Sequence; Catechin; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Proline; Protein Conformation | 2002 |
Gene expression profile in human prostate LNCaP cancer cells by (--) epigallocatechin-3-gallate.
Topics: Anticarcinogenic Agents; Catechin; Gene Expression Profiling; Humans; Isoenzymes; Male; Mitogen-Activated Protein Kinases; Oligonucleotide Array Sequence Analysis; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms; Protein Kinase C; Receptor, trkA; Tea | 2002 |
Inhibition of beta-catenin/Tcf activity by white tea, green tea, and epigallocatechin-3-gallate (EGCG): minor contribution of H(2)O(2) at physiologically relevant EGCG concentrations.
Topics: Anticarcinogenic Agents; beta Catenin; Catechin; Cell Line; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Humans; Hydrogen Peroxide; Kinetics; TCF Transcription Factors; Tea; Trans-Activators; Transcription Factor 7-Like 2 Protein; Transcription Factors; Transcriptional Activation | 2002 |
Identification and characterization of methylated and ring-fission metabolites of tea catechins formed in humans, mice, and rats.
Topics: Adult; Animals; Antioxidants; Catechin; Chromatography; Female; Half-Life; Humans; Male; Mass Spectrometry; Mice; Rats; Tea | 2002 |
Polyphenol-induced inhibition of the response of na(+)/glucose cotransporter expressed in Xenopus oocytes.
Topics: Animals; Catechin; Cell Membrane; Electric Conductivity; Female; Flavonoids; Galactose; Gene Expression; Glucose; Intestine, Small; Membrane Glycoproteins; Monosaccharide Transport Proteins; Oocytes; Patch-Clamp Techniques; Phenols; Polymers; Rats; Saponins; Sodium-Glucose Transporter 1; Tea; Xenopus laevis | 2002 |
Protective effects of green tea polyphenols and their major component, (-)-epigallocatechin-3-gallate (EGCG), on 6-hydroxydopamine-induced apoptosis in PC12 cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Catechin; Cell Survival; Flavonoids; Hydroxydopamines; Kinetics; PC12 Cells; Phenols; Pheochromocytoma; Plant Extracts; Polymers; Rats; Tea | 2002 |
Spectrofluorometric determination of catechins with 1,2-diphenylethylenediamine.
Topics: Catechin; Dose-Response Relationship, Drug; Ethylenediamines; Ferricyanides; Kinetics; Spectrometry, Fluorescence; Tea | 2002 |
Topical applications of caffeine or (-)-epigallocatechin gallate (EGCG) inhibit carcinogenesis and selectively increase apoptosis in UVB-induced skin tumors in mice.
Topics: Administration, Topical; Animals; Apoptosis; Bromodeoxyuridine; Caffeine; Caspase 3; Caspases; Catechin; Female; Mice; Mice, Hairless; Neoplasms, Radiation-Induced; Skin Neoplasms; Tea; Ultraviolet Rays | 2002 |
Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and recep
Topics: Antioxidants; Apoptosis; Blotting, Western; Caspase 8; Caspase 9; Caspases; Catechin; Cell Death; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Etoposide; Flavonoids; Flow Cytometry; Glutathione; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinase 5; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Models, Biological; NF-kappa B; Nucleic Acid Synthesis Inhibitors; Oxidation-Reduction; Oxygen; p38 Mitogen-Activated Protein Kinases; Phenols; Polymers; Reactive Oxygen Species; Signal Transduction; Time Factors; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; U937 Cells; Urokinase-Type Plasminogen Activator | 2002 |
Suppression of cytotoxin-induced cell death in isolated hepatocytes by tea catechins.
Topics: Animals; Bromobenzenes; Caspase 3; Caspases; Catechin; Cell Death; Cell Survival; Cells, Cultured; Enzyme Induction; Hepatocytes; In Vitro Techniques; Male; Mycotoxins; Protective Agents; Rats; Rats, Sprague-Dawley; Tea | 2002 |
Epigallocatechin-3-gallate inhibits interleukin-1beta-induced expression of nitric oxide synthase and production of nitric oxide in human chondrocytes: suppression of nuclear factor kappaB activation by degradation of the inhibitor of nuclear factor kappa
Topics: Antioxidants; Cartilage, Articular; Catechin; Cells, Cultured; Chondrocytes; DNA; DNA-Binding Proteins; Humans; I-kappa B Proteins; Interleukin-1; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Osteoarthritis, Knee; RNA, Messenger | 2002 |
The antioxidant (-)-epigallocatechin-3-gallate inhibits activated hepatic stellate cell growth and suppresses acetaldehyde-induced gene expression.
Topics: Alcohols; Animals; Antioxidants; Apoptosis; Blotting, Western; Bromodeoxyuridine; Catechin; Cell Division; Cells, Cultured; Collagen Type I; Dose-Response Relationship, Drug; Fibronectins; Flow Cytometry; Gene Expression Regulation; Hepatocytes; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Male; Models, Chemical; NF-kappa B; Plasmids; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleases; RNA, Messenger; Tea; Thymidine; Time Factors; Transfection; Transforming Growth Factor beta | 2002 |
Effect of tea catechins on cellular lipid peroxidation and cytotoxicity in HepG2 cells.
Topics: Antineoplastic Agents, Phytogenic; Catechin; Dose-Response Relationship, Drug; Enzyme Activation; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Humans; Lipid Peroxidation; Liver Neoplasms; Tea; tert-Butylhydroperoxide; Thiobarbituric Acid Reactive Substances; Tumor Cells, Cultured; Vitamin E | 2002 |
Enhancing effect of zinc on hepatoprotectivity of epigallocatechin gallate in isolated rat hepatocytes.
Topics: Animals; Bromobenzenes; Catechin; Cell Separation; Cells, Cultured; Chlorides; Drug Synergism; Hepatocytes; Male; Rats; Rats, Sprague-Dawley; Zinc Compounds | 2002 |
Inhibition of bcl-x(l) phosphorylation by tea polyphenols or epigallocatechin-3-gallate is associated with prostate cancer cell apoptosis.
Topics: Apoptosis; bcl-X Protein; Catechin; Down-Regulation; Flavonoids; Gene Expression; Humans; Male; Mitochondria; Phenols; Phosphorylation; Polymers; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Tea; Tumor Cells, Cultured | 2002 |
A green tea-derived polyphenol, epigallocatechin-3-gallate, inhibits IkappaB kinase activation and IL-8 gene expression in respiratory epithelium.
Topics: Antioxidants; Catechin; Enzyme Activation; Flavonoids; Humans; I-kappa B Kinase; Interleukin-8; NF-kappa B; Phenols; Polymers; Protein Serine-Threonine Kinases; Respiratory Mucosa; RNA, Messenger; Tea; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Topics: Adenomatous Polyposis Coli Protein; Animals; Anti-Inflammatory Agents, Non-Steroidal; beta Catenin; Catechin; Cell Line; Cytoskeletal Proteins; Drug Combinations; Imidazoles; Intestinal Mucosa; Intestinal Neoplasms; Luciferases; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Plant Extracts; Polyps; Sulindac; Tea; Trans-Activators | 2002 |
Green tea polyphenol epigallocatechin-3-gallate inhibits the IL-1 beta-induced activity and expression of cyclooxygenase-2 and nitric oxide synthase-2 in human chondrocytes.
Topics: Antioxidants; Catechin; Cells, Cultured; Chondrocytes; Cyclooxygenase 2; Depression, Chemical; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Interleukin-1; Isoenzymes; L-Lactate Dehydrogenase; Membrane Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Reactive Oxygen Species; Tea | 2002 |
Regulation of IGFBP-5 expression during tumourigenesis and differentiation of oral keratinocytes.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Catechin; Cell Differentiation; Cell Transformation, Neoplastic; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Library; Humans; Insulin-Like Growth Factor Binding Protein 5; Keratinocytes; Male; Middle Aged; Mouth Neoplasms; Neoplasm Proteins; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured; Up-Regulation | 2002 |
Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability.
Topics: Administration, Oral; Adult; Antioxidants; Biological Availability; Biomarkers; Catechin; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Male; Reproducibility of Results; Tea; Urokinase-Type Plasminogen Activator | 2002 |
Differential modulation of growth and glutathione metabolism in cultured rat astrocytes by 4-hydroxynonenal and green tea polyphenol, epigallocatechin-3-gallate.
Topics: Aldehydes; Animals; Apoptosis; Astrocytes; Blotting, Western; Catechin; Flavonoids; Glutathione; Glutathione Transferase; Immunohistochemistry; Isoenzymes; Lipid Peroxidation; Mitochondria; Oxidative Stress; Phenols; Polymers; Rats; Rats, Wistar; Tea; Tetrazolium Salts; Thiazoles | 2002 |
Prevention of nitric oxide-mediated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease in mice by tea phenolic epigallocatechin 3-gallate.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Blotting, Western; Catechin; Dopamine Agents; Homovanillic Acid; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Parkinson Disease, Secondary; RNA, Messenger; Substantia Nigra; Tea; Tyrosine 3-Monooxygenase | 2002 |
Stimulatory effect of topical application of caffeine on UVB-induced apoptosis in mouse skin.
Topics: Administration, Topical; Animals; Apoptosis; Caffeine; Caspase 3; Caspases; Catechin; Cell Division; Mice; Skin; Tumor Suppressor Protein p53; Ultraviolet Rays | 2002 |
The specific anti-cancer activity of green tea (-)-epigallocatechin-3-gallate (EGCG).
Topics: 3T3 Cells; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Blotting, Western; Catechin; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Cyclophosphamide; Drug Screening Assays, Antitumor; Genes, ras; Humans; Leukemia; Mice; Mitogen-Activated Protein Kinases; Ornithine Decarboxylase; Phosphorylation; Tea; Tumor Cells, Cultured | 2002 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced inflammatory skin edema and ornithine decarboxylase activity by theaflavin-3,3'-digallate in mouse.
Topics: 3T3 Cells; Animals; Anticarcinogenic Agents; Biflavonoids; Catechin; Edema; Enzyme Inhibitors; Female; Gallic Acid; Mice; Mice, Inbred BALB C; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Promoter Regions, Genetic; RNA, Messenger; Tetradecanoylphorbol Acetate | 2002 |
Direct scavenging of nitric oxide and superoxide by green tea.
Topics: Catechin; Dose-Response Relationship, Drug; Flavonoids; Free Radical Scavengers; In Vitro Techniques; Nitric Oxide; Oxidants; Oxidation-Reduction; Structure-Activity Relationship; Superoxides; Tannins; Tea | 2002 |
Anti-proliferative and differentiation-inducing activities of the green tea catechin epigallocatechin-3-gallate (EGCG) on the human eosinophilic leukemia EoL-1 cell line.
Topics: Antineoplastic Agents, Phytogenic; Blood Proteins; Catechin; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; Eosinophil Granule Proteins; Eosinophil Peroxidase; Growth Inhibitors; Humans; Hypereosinophilic Syndrome; Kinetics; Peroxidases; Ribonucleases; RNA, Neoplasm; Tumor Cells, Cultured | 2002 |
Green tea polyphenols inhibit metalloproteinase activities in the skin, muscle, and blood of rainbow trout.
Topics: Animals; Catechin; Chromatography, High Pressure Liquid; Edetic Acid; Enzyme Inhibitors; Flavonoids; Gelatinases; Metalloendopeptidases; Muscle, Skeletal; Oncorhynchus mykiss; Phenols; Polymers; Skin; Tea | 2002 |
Tea enhances insulin activity.
Topics: Adipocytes; Animals; Biflavonoids; Camellia sinensis; Catechin; Chemical Fractionation; Chromatography, High Pressure Liquid; Drug Synergism; Epididymis; Flavonoids; Glucose; Insulin; Male; Milk; Phenols; Plant Extracts; Polymers; Rats; Tannins; Tea | 2002 |
Inhibitory effects of epigallocatechin-3-gallate on N-nitrosomethylbenzylamine-induced esophageal tumorigenesis in F344 rats.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cyclin D1; Cyclooxygenase 1; Cyclooxygenase 2; Dimethylnitrosamine; Dinoprostone; Disease Models, Animal; DNA Primers; Enzyme-Linked Immunosorbent Assay; Esophageal Neoplasms; Esophagus; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Urokinase-Type Plasminogen Activator | 2002 |
Analysis of cell growth inhibitory effects of catechin through MAPK in human breast cancer cell line T47D.
Topics: Breast Neoplasms; Carrier Proteins; Catechin; CDC2-CDC28 Kinases; Cell Division; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Cyclins; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Tumor Cells, Cultured | 2002 |
The green tea polyphenol, epigallocatechin-3-gallate, protects against the oxidative cellular and genotoxic damage of UVA radiation.
Topics: Antimutagenic Agents; Antioxidants; Catechin; Cell Survival; Cells, Cultured; DNA Damage; Humans; Keratinocytes; Radiation-Protective Agents; Ultraviolet Rays | 2002 |
(-)-Epigallocatechin gallate protects against NO stress-induced neuronal damage after ischemia by acting as an anti-oxidant.
Topics: Animals; Antioxidants; Brain Ischemia; Catechin; Cell Survival; Cells, Cultured; Cerebrovascular Circulation; Hippocampus; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxidative Stress; Rats; Rats, Wistar | 2002 |
Additive, indifferent and antagonistic effects in combinations of epigallocatechin gallate with 12 non-beta-lactam antibiotics against methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Catechin; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Humans; Methicillin Resistance; Staphylococcus aureus | 2002 |
Telomere shortening and growth inhibition of human cancer cells by novel synthetic telomerase inhibitors MST-312, MST-295, and MST-1991.
Topics: Antineoplastic Agents; Apoptosis; Benzamides; beta-Galactosidase; Blotting, Southern; Catechin; Chromones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Models, Chemical; Phenotype; Telomerase; Telomere; Time Factors; U937 Cells | 2002 |
Kinetic evaluation of the reactivity of flavonoids as radical scavengers.
Topics: Catechin; Flavonoids; Free Radical Scavengers; Free Radicals; Hesperidin; Kinetics; Molecular Structure; Polymers; Propyl Gallate; Quercetin; Resveratrol; Stilbenes; Structure-Activity Relationship | 2002 |
(-)Epigallocatechin-3-gallate directly inhibits MT1-MMP activity, leading to accumulation of nonactivated MMP-2 at the cell surface.
Topics: Catechin; Cell Membrane; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fibrosarcoma; Flow Cytometry; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Microscopy, Confocal; Protease Inhibitors; Tumor Cells, Cultured | 2002 |
Antiinflammatory action of EGCG, the main component of green tea, through STAT-1 inhibition.
Topics: Animals; Antineoplastic Agents, Phytogenic; Catechin; DNA-Binding Proteins; Flavonoids; Gallic Acid; Gene Expression Regulation, Neoplastic; Humans; Phenols; Polymers; Signal Transduction; STAT1 Transcription Factor; Trans-Activators; Tumor Cells, Cultured | 2002 |
Inhibition of BMP-induced ectopic bone formation by an antiangiogenic agent (epigallocatechin 3-gallate).
Topics: Alkaline Phosphatase; Angiogenesis Inhibitors; Animals; Bone and Bones; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Calcium; Cartilage; Catechin; Choristoma; Collagen Type II; Drug Delivery Systems; Humans; Male; Osteogenesis; Rats; Rats, Wistar; Skin Diseases; Transforming Growth Factor beta | 2002 |
Purification of long-chain fatty acid ester of epigallocatechin-3-O-gallate by high-speed counter-current chromatography.
Topics: Catechin; Countercurrent Distribution; Esters; Fatty Acids; Spectrum Analysis | 2002 |
The relation between single/double or repeated tea catechin ingestions and plasma antioxidant activity in humans.
Topics: Adult; alpha-Tocopherol; Antioxidants; Ascorbic Acid; Bilirubin; Catechin; Cholesterol; Dose-Response Relationship, Drug; Female; Flavonoids; Humans; Kinetics; Phenols; Plant Extracts; Polymers; Tea; Uric Acid | 2002 |
Mechanisms involved in the differential bone marrow homing of CD45 subsets in 5T murine models of myeloma.
Topics: Animals; Bone Marrow; Catechin; Cell Adhesion; Cells, Cultured; Chemotaxis; Endothelium; Fibroblasts; Laminin; Leukocyte Common Antigens; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C57BL; Multiple Myeloma; Neoplasm Invasiveness; Neoplasms, Experimental; Protease Inhibitors; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; T-Lymphocyte Subsets; Urokinase-Type Plasminogen Activator | 2002 |
Stability, cellular uptake, biotransformation, and efflux of tea polyphenol (-)-epigallocatechin-3-gallate in HT-29 human colon adenocarcinoma cells.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotransformation; Catechin; Drug Stability; HT29 Cells; Humans; Hydrogen Peroxide; Indomethacin; Oxidation-Reduction; Probenecid; Temperature; Tritium; Vinblastine | 2002 |
Inhibitory activity of epigallocatechin gallate (EGCg) in paraquat-induced microsomal lipid peroxidation--a mechanism of protective effects of EGCg against paraquat toxicity.
Topics: Animals; Antioxidants; Catechin; Cyclic N-Oxides; Deferoxamine; Drug Interactions; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Herbicides; Iron Chelating Agents; Lipid Peroxidation; Lipid Peroxides; Male; Malondialdehyde; Microsomes, Liver; Paraquat; Rats; Rats, Wistar; Spin Trapping; Superoxides; Tea | 2003 |
Induction of poly(ADP-ribosyl)ation and DNA damage in human peripheral lymphocytes after treatment with (-)-epigallocatechin-gallate.
Topics: Antimutagenic Agents; Catechin; Cells, Cultured; Comet Assay; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Humans; Leukemia, B-Cell; Lymphocytes; Poly Adenosine Diphosphate Ribose; Toxicity Tests | 2003 |
Epigallocatechin-3-gallate selectively inhibits interleukin-1beta-induced activation of mitogen activated protein kinase subgroup c-Jun N-terminal kinase in human osteoarthritis chondrocytes.
Topics: Antineoplastic Agents; Catechin; Cell Survival; Chondrocytes; DNA; Enzyme Activation; Humans; In Vitro Techniques; Interleukin-1; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Osteoarthritis, Knee; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-jun; Transcription Factor AP-1 | 2003 |
Black tea represents a major source of dietary phenolics among regular tea drinkers.
Topics: Antioxidants; Biflavonoids; Camellia sinensis; Catechin; Coumaric Acids; Diet; Flavonoids; Flavonols; Gallic Acid; Gastric Juice; Humans; Phenols; Plant Leaves; Polymers; Polyphenols; Tea | 2002 |
Epimerization of tea catechins and O-methylated derivatives of (-)-epigallocatechin-3-O-gallate: relationship between epimerization and chemical structure.
Topics: Catechin; Hot Temperature; Hydrogen-Ion Concentration; Methylation; Molecular Structure; Plant Extracts; Plant Leaves; Solutions; Stereoisomerism; Tea; Water | 2003 |
The specificities of protein kinase inhibitors: an update.
Topics: Alkaloids; Anthracenes; Azepines; Benzazepines; Carbazoles; Catechin; Cyclin-Dependent Kinases; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Indoles; JNK Mitogen-Activated Protein Kinases; Kinetin; Mitogen-Activated Protein Kinases; Naphthalenes; Oximes; Protein Kinase Inhibitors; Purines; Pyrazoles; Pyrimidines; Signal Transduction; src-Family Kinases; Substrate Specificity | 2003 |
(-)-Epigallocatechin-3-gallate enhances anti-tumor effect of cytosine arabinoside on HL-60 cells.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Calcium; Catechin; Cell Cycle; Cell Division; Cytarabine; Drug Synergism; HL-60 Cells; Humans; Inhibitory Concentration 50; Proto-Oncogene Proteins c-bcl-2; Stereoisomerism | 2003 |
Molecular pathway for (-)-epigallocatechin-3-gallate-induced cell cycle arrest and apoptosis of human prostate carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma; Carrier Proteins; Catechin; Cell Cycle; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p18; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Dose-Response Relationship, Drug; Enzyme Inhibitors; G1 Phase; Humans; Intracellular Signaling Peptides and Proteins; Male; Prostatic Neoplasms; Signal Transduction; Tumor Suppressor Proteins | 2003 |
Growth inhibition, induction of apoptosis by green tea constituent (-)-epigallocatechin-3-gallate in cultured rabbit lens epithelial cells.
Topics: Animals; Antioxidants; Apoptosis; Cataract; Catechin; Cell Division; Cell Survival; Cells, Cultured; Epithelial Cells; Lens, Crystalline; Rabbits; Tea | 2000 |
Green tea polyphenol epigallocatechin-3 gallate induces apoptosis of proliferating vascular smooth muscle cells via activation of p53.
Topics: Animals; Apoptosis; Blotting, Northern; Catechin; Cattle; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Gene Expression Regulation; Immunoblotting; In Situ Nick-End Labeling; Muscle, Smooth, Vascular; NF-kappa B; RNA, Messenger; Tea; Tumor Suppressor Protein p53 | 2003 |
Inhibition of Epstein-Barr virus lytic cycle by (-)-epigallocatechin gallate.
Topics: Antiviral Agents; Catechin; Epstein-Barr Virus Nuclear Antigens; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Genes, Immediate-Early; Herpesvirus 4, Human; Humans; Oligonucleotide Array Sequence Analysis; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Viral Proteins | 2003 |
Blocking telomerase by dietary polyphenols is a major mechanism for limiting the growth of human cancer cells in vitro and in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Catechin; Cell Division; Colonic Neoplasms; Enzyme Inhibitors; Female; Flavonoids; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Osteosarcoma; Phenols; Polymers; Telomerase; Tumor Cells, Cultured; U937 Cells; Xenograft Model Antitumor Assays | 2003 |
Inhibition of ultraviolet B-mediated activation of nuclear factor kappaB in normal human epidermal keratinocytes by green tea Constituent (-)-epigallocatechin-3-gallate.
Topics: Active Transport, Cell Nucleus; Anticarcinogenic Agents; Catechin; Cell Nucleus; Cells, Cultured; Cytoplasm; Dose-Response Relationship, Drug; Epidermal Cells; Humans; I-kappa B Kinase; I-kappa B Proteins; Keratinocytes; MAP Kinase Signaling System; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Radiation-Protective Agents; Tea; Transcription Factor RelA; Transcription, Genetic; Ultraviolet Rays | 2003 |
(-)Epigallocatechin-3-gallate inhibits gelatinase activity of some bacterial isolates from ocular infection, and limits their invasion through gelatine.
Topics: Anti-Bacterial Agents; Bacteria; Catechin; Culture Media; Electrophoresis, Polyacrylamide Gel; Eye Infections, Bacterial; Gelatin; Gelatinases; Humans; Microbial Sensitivity Tests; Tea | 2003 |
(-)-Epigallocatechin-3-gallate prevents oxidative damage in both the aqueous and lipid compartments of human plasma.
Topics: alpha-Tocopherol; Antioxidants; Catechin; Cell Compartmentation; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Humans; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Oxidation-Reduction; Phenols; Plasma | 2003 |
Regulation of hazardous exposure by protective exposure: modulation of phase II detoxification and lipid peroxidation by Camellia sinensis and Swertia chirata.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Biflavonoids; Camellia sinensis; Carcinogens; Catalase; Catechin; Enzyme Activation; Glutathione Peroxidase; Glutathione Transferase; Hazardous Substances; Inactivation, Metabolic; Lipid Peroxidation; Liver; Male; Mice; Plant Extracts; Plants, Medicinal; Superoxide Dismutase; Swertia; Tea | 2003 |
cDNA gene expression profile homology of antioxidants and their antiapoptotic and proapoptotic activities in human neuroblastoma cells.
Topics: Antioxidants; Apomorphine; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Catechin; Cell Survival; Dopamine; Dose-Response Relationship, Drug; Gene Expression Profiling; Gene Expression Regulation; Humans; Melatonin; Neuroblastoma; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2003 |
The relationship between the antioxidant and the antibacterial properties of galloylated catechins and the structure of phospholipid model membranes.
Topics: Anti-Bacterial Agents; Antioxidants; Bacteria; Calorimetry, Differential Scanning; Catechin; Fluorescence Polarization; Lipid Bilayers; Oxidation-Reduction; Phosphatidylcholines; Phosphatidylethanolamines; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Tea | 2003 |
Glucuronides of tea catechins: enzymology of biosynthesis and biological activities.
Topics: Animals; Arachidonic Acid; Catechin; Cells, Cultured; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cytosol; Dose-Response Relationship, Drug; Female; Gas Chromatography-Mass Spectrometry; Glucuronides; Glucuronosyltransferase; Humans; In Vitro Techniques; Insecta; Intestinal Mucosa; Intestines; Kinetics; Liver; Male; Mice; Mice, Inbred Strains; Microsomes; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Species Specificity | 2003 |
Association of suppression of extracellular signal-regulated kinase phosphorylation by epigallocatechin gallate with the reduction of matrix metalloproteinase activities in human fibrosarcoma HT1080 cells.
Topics: Camellia sinensis; Catechin; Enzyme Inhibitors; Fibrosarcoma; Gene Expression Regulation, Enzymologic; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Plant Leaves; RNA, Messenger; Tea; Tumor Cells, Cultured | 2003 |
Factors affecting the levels of tea polyphenols and caffeine in tea leaves.
Topics: Caffeine; Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Flavonoids; Free Radical Scavengers; Hot Temperature; Hydroxyl Radical; Phenols; Plant Extracts; Plant Leaves; Polymers; Tea | 2003 |
Presence of two forms of methylated (-)-epigallocatechin-3-gallate in green tea.
Topics: Antioxidants; Catechin; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Magnetic Resonance Spectroscopy; Mass Spectrometry; Tea | 2003 |
Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and alpha-lipoic acid differentially reduce oxidative DNA damage induced by Fenton reagents: a study of their individual and synergistic actions.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Antioxidants; Ascorbic Acid; Catechin; Chromium; Deoxyguanosine; DNA Damage; Dose-Response Relationship, Drug; Drug Synergism; Hydrogen Peroxide; Inhibitory Concentration 50; Iron; Melatonin; Oxidative Stress; Resveratrol; Stilbenes; Thioctic Acid; Xanthurenates | 2003 |
Resveratrol-induced modification of polyamine metabolism is accompanied by induction of c-Fos.
Topics: Acetyltransferases; Adenocarcinoma; Adenosylmethionine Decarboxylase; Anticarcinogenic Agents; Base Sequence; Caco-2 Cells; Catechin; Colonic Neoplasms; DNA Primers; Gene Expression Regulation; Humans; Ornithine Decarboxylase; Polyamines; Proto-Oncogene Proteins c-fos; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2003 |
In vitro assessment of inhibition by natural polyphenols of metabolic activation of procarcinogens by human CYP1A1.
Topics: Anticarcinogenic Agents; Benzo(a)pyrene; Biotransformation; Carcinogens; Catechin; Cytochrome P-450 CYP1A1; Enzyme Inhibitors; Flavonoids; Humans; In Vitro Techniques; Phenols; Polymers; Resveratrol; Stilbenes | 2003 |
Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3-gallate.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Catechin; Cell Survival; Enzyme Activation; Enzyme Inhibitors; Hippocampus; Humans; Hydroxamic Acids; Indoles; Isoenzymes; Maleimides; Metalloendopeptidases; Mice; Neuroprotective Agents; PC12 Cells; Peptide Fragments; Protein Kinase C; Rats; Tumor Cells, Cultured | 2003 |
Protective effect of green tea polyphenol (-)-epigallocatechin gallate and other antioxidants on lipid peroxidation in gerbil brain homogenates.
Topics: Animals; Antioxidants; Brain; Catechin; Chromans; Dose-Response Relationship, Drug; Ferrous Compounds; Flavonoids; Gerbillinae; Hydrogen Peroxide; Inhibitory Concentration 50; Lipid Peroxidation; Male; Melatonin; Phenols; Phytotherapy; Polymers; Quaternary Ammonium Compounds; Tea; Thiobarbituric Acid Reactive Substances; Thioctic Acid | 2003 |
Enzymology of methylation of tea catechins and inhibition of catechol-O-methyltransferase by (-)-epigallocatechin gallate.
Topics: Animals; Catechin; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cytosol; Enzyme Inhibitors; Female; Gas Chromatography-Mass Spectrometry; Glucuronides; Intestinal Mucosa; Intestines; Liver; Male; Methylation; Mice; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Species Specificity; Swine; Tea | 2003 |
The antioxidant (-)-epigallocatechin-3-gallate inhibits rat hepatic stellate cell proliferation in vitro by blocking the tyrosine phosphorylation and reducing the gene expression of platelet-derived growth factor-beta receptor.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Catechin; Cell Division; Dose-Response Relationship, Drug; Gene Expression Regulation; Hepatocytes; Male; Phosphorylation; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptor, Platelet-Derived Growth Factor beta; RNA Stability; Tyrosine | 2003 |
Evaluation of the redox properties and anti/pro-oxidant effects of selected flavonoids by means of a DNA-based electrochemical biosensor.
Topics: Antioxidants; Biosensing Techniques; Catechin; DNA; Electrochemistry; Flavonoids; Molecular Structure; Oxidants; Oxidation-Reduction; Quercetin; Rutin | 2003 |
Green tea epigallocatechin-3-gallate inhibits platelet signalling pathways triggered by both proteolytic and non-proteolytic agonists.
Topics: Animals; Blood Platelets; Calcium; Catechin; Enzyme Precursors; Humans; Intracellular Signaling Peptides and Proteins; Peptide Hydrolases; Platelet Activation; Protein-Tyrosine Kinases; Rats; Signal Transduction; src-Family Kinases; Syk Kinase; Tea; Thrombin | 2003 |
Antitumor principle constituents of Myrica rubra Var. acuminata.
Topics: Animals; Anthocyanins; Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Catechin; Cell Division; Cervix Uteri; Female; Fibroblasts; HeLa Cells; Humans; Leukemia P388; Methanol; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Middle Aged; Myrica; Neoplasm Transplantation; Plant Extracts; Plant Leaves | 2003 |
A novel convenient process to obtain a raw decaffeinated tea polyphenol fraction using a lignocellulose column.
Topics: Caffeine; Camellia sinensis; Catechin; Cellulose; Chromatography, High Pressure Liquid; Flavonoids; Hydrogen-Ion Concentration; Lignin; Phenols; Plant Extracts; Polymers | 2003 |
Comparison of green tea extract and epigallocatechin gallate on blood pressure and contractile responses of vascular smooth muscle of rats.
Topics: Animals; Aorta; Blood Pressure; Catechin; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Tea; Vasoconstriction | 2003 |
Antioxidative compounds from Crotalaria sessiliflora.
Topics: Antioxidants; Biphenyl Compounds; Catechin; Chemical Fractionation; Crotalaria; Free Radical Scavengers; Free Radicals; Hydrazines; Linoleic Acid; Lipid Peroxidation; Oxidation-Reduction; Picrates; Plant Components, Aerial; Plant Extracts; tert-Butylhydroperoxide | 2003 |
Sodium orthovanadate potentiates EGCG-induced apoptosis that is dependent on the ERK pathway.
Topics: Anticarcinogenic Agents; Apoptosis; Caspase 3; Caspases; Catechin; Cytochrome c Group; Drug Synergism; Enzyme Inhibitors; Flavonoids; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Protein Tyrosine Phosphatases; Proteins; Proto-Oncogene Proteins c-bcl-2; U937 Cells; Vanadates | 2003 |
Inhibition of adenovirus infection and adenain by green tea catechins.
Topics: Adenoviridae; Antiviral Agents; Catechin; Cell Line; Cell Survival; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Tea; Virion; Virus Replication | 2003 |
Radical chemistry of epigallocatechin gallate and its relevance to protein damage.
Topics: Antioxidants; Catechin; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen-Ion Concentration; Oxidation-Reduction; Serum Albumin, Bovine; Zinc Acetate | 2003 |
Tea catechin synergies in inhibition of cancer cell proliferation and of a cancer specific cell surface oxidase (ECTO-NOX).
Topics: Antineoplastic Agents; Antioxidants; Beverages; Catechin; Cell Division; Drug Synergism; HeLa Cells; Humans; Microscopy, Fluorescence; NADH, NADPH Oxidoreductases; Plant Extracts; Structure-Activity Relationship; Tea; Time Factors | 2003 |
Epigallocatechin gallate, a constituent of green tea, suppresses cytokine-induced pancreatic beta-cell damage.
Topics: Animals; Blotting, Western; Catechin; Cell Line; Cell Survival; Cytokines; Interferon-gamma; Interleukin-1; Islets of Langerhans; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Tea | 2003 |
Treatment of green tea polyphenols in hydrophilic cream prevents UVB-induced oxidation of lipids and proteins, depletion of antioxidant enzymes and phosphorylation of MAPK proteins in SKH-1 hairless mouse skin.
Topics: Animals; Blotting, Western; Catalase; Catechin; Female; Glutathione; Glutathione Peroxidase; JNK Mitogen-Activated Protein Kinases; Lipid Metabolism; Lipid Peroxidation; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mice; Mice, Hairless; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Ointments; Oxidative Stress; Oxidoreductases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proteins; Radiation-Protective Agents; Skin; Tea; Ultraviolet Rays | 2003 |
Malondialdehyde production in Jurkat T cells subjected to oxidative stress.
Topics: Catechin; Ferrous Compounds; Genistein; Humans; Hydrogen Peroxide; Jurkat Cells; Lipid Peroxidation; Malondialdehyde; Membrane Lipids; Oxidative Stress; T-Lymphocytes | 2003 |
Epigallocatechin-3-gallate binding to MMP-2 inhibits gelatinolytic activity without influencing the attachment to extracellular matrix proteins but enhances MMP-2 binding to TIMP-2.
Topics: Catechin; Collagen Type I; Electrophoresis, Agar Gel; Enzyme Activation; Extracellular Matrix Proteins; Gelatin; Gelatinases; Hydrolysis; Matrix Metalloproteinase 2; Protein Binding; Reproducibility of Results; Sensitivity and Specificity; Substrate Specificity; Tissue Inhibitor of Metalloproteinase-2 | 2003 |
Inhibitory effects of green tea catechins on the activity of human matrix metalloproteinase 7 (matrilysin).
Topics: Catechin; Chlorides; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Matrix Metalloproteinase 7; Matrix Metalloproteinase Inhibitors; Spectrometry, Fluorescence; Tea; Zinc Compounds | 2003 |
A major constituent of green tea, EGCG, inhibits the growth of a human cervical cancer cell line, CaSki cells, through apoptosis, G(1) arrest, and regulation of gene expression.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camellia sinensis; Carcinogenicity Tests; Carcinoma; Catechin; Cell Division; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Flow Cytometry; G1 Phase; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Oligonucleotide Array Sequence Analysis; Papillomaviridae; Tumor Cells, Cultured; Tumor Virus Infections; Uterine Cervical Neoplasms | 2003 |
Comparative effects of polyphenols from green tea (EGCG) and soybean (genistein) on VEGF and IL-8 release from normal human keratinocytes stimulated with the proinflammatory cytokine TNFalpha.
Topics: Angiogenesis Inhibitors; Catechin; Cell Division; Cells, Cultured; Down-Regulation; Genistein; Growth Inhibitors; Humans; Interleukin-8; Keratinocytes; Plant Extracts; Tea; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2003 |
Epigallocatechin-3-gallate-induced stress signals in HT-29 human colon adenocarcinoma cells.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Antioxidants; Apoptosis; Blotting, Western; Caspase 3; Caspase 9; Caspases; Catalase; Catechin; Colonic Neoplasms; Cytochrome c Group; DNA, Neoplasm; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Glutathione; HT29 Cells; Humans; JNK Mitogen-Activated Protein Kinases; Membrane Potentials; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Oxidants; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Urokinase-Type Plasminogen Activator | 2003 |
Complex effects of different green tea catechins on human platelets.
Topics: Blood Platelets; Catechin; Flow Cytometry; Humans; Phosphorylation; Platelet Aggregation; Signal Transduction; Tea; Thrombin; Tyrosine | 2003 |
Proteinase-3 directly activates MMP-2 and degrades gelatin and Matrigel; differential inhibition by (-)epigallocatechin-3-gallate.
Topics: Catechin; Coculture Techniques; Collagen; Drug Combinations; Extracellular Matrix; Gelatin; Humans; Laminin; Matrix Metalloproteinase 2; Myeloblastin; Neoplasm Invasiveness; Neutrophils; Protease Inhibitors; Proteoglycans; Serine Endopeptidases; Tumor Cells, Cultured | 2003 |
Combinatorial effects of nonsteroidal anti-inflammatory drugs and food constituents on production of prostaglandin E2 and tumor necrosis factor-alpha in RAW264.7 murine macrophages.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Catechin; Cell Line; Cyclooxygenase Inhibitors; Dinoprostone; Drug Synergism; Food Analysis; Food-Drug Interactions; Genistein; Indicators and Reagents; Indomethacin; Interferon-gamma; Isothiocyanates; Lipopolysaccharides; Macrophages; Mice; Protein Biosynthesis; Spectrophotometry, Infrared; Sulfonamides; Tumor Necrosis Factor-alpha | 2003 |
Restoration of antibacterial activity of beta-lactams by epigallocatechin gallate against beta-lactamase-producing species depending on location of beta-lactamase.
Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Catechin; Drug Synergism; Gram-Negative Bacteria; Microbial Sensitivity Tests | 2003 |
Gene and protein expression profiles of anti- and pro-apoptotic actions of dopamine, R-apomorphine, green tea polyphenol (-)-epigallocatechine-3-gallate, and melatonin.
Topics: Antioxidants; Apomorphine; Apoptosis; Catechin; Cell Line; Cell Survival; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Gene Expression Profiling; Gene Expression Regulation; Humans; Melatonin; Neuroprotective Agents; Oligonucleotide Array Sequence Analysis | 2003 |
Identification of potential aryl hydrocarbon receptor antagonists in green tea.
Topics: Animals; Catechin; Dose-Response Relationship, Drug; Genes, Reporter; Luciferases; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Plant Extracts; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Tea; Transcription, Genetic; Tumor Cells, Cultured | 2003 |
Effect of EGCG on lipid absorption and plasma lipid levels in rats.
Topics: Animals; Catechin; Cholesterol; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Diet; Fatty Acids, Nonesterified; Feces; Female; Intestinal Absorption; Lipids; Liver; Micelles; Rats; Rats, Wistar; Solubility; Triglycerides | 2003 |
Analysis of oxidized epigallocatechin gallate by liquid chromatography/mass spectrometry.
Topics: Catechin; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Oxidation-Reduction; Spectrometry, Mass, Electrospray Ionization | 2003 |
Quantification of doxorubicin and validation of reversal effect of tea polyphenols on multidrug resistance in human carcinoma cells.
Topics: Carcinoma, Squamous Cell; Catechin; Cell Division; Cell Survival; Chromatography, High Pressure Liquid; Doxorubicin; Drug Resistance, Multiple; Flavonoids; Humans; Mouth Neoplasms; Phenols; Polymers; Tea; Tumor Cells, Cultured | 2003 |
Inhibitory effect of catechin against the superantigen staphylococcal enterotoxin B (SEB).
Topics: Animals; Antioxidants; Blotting, Western; Catechin; Cytokines; Dermatitis, Atopic; Dose-Response Relationship, Drug; Enterotoxins; Female; Galactosamine; Leukocytes, Mononuclear; Mice; Mice, Inbred BALB C; RNA, Messenger; Superantigens; Tea | 2003 |
Role of p53 and NF-kappaB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cells.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 8; Caspase 9; Caspases; Catechin; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA, Neoplasm; Enzyme Activation; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Male; Neoplasm Proteins; NF-kappa B; Nuclear Proteins; Phosphorylation; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-mdm2; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p14ARF; Tumor Suppressor Protein p53 | 2003 |
Dual mechanisms of green tea extract (EGCG)-induced cell survival in human epidermal keratinocytes.
Topics: Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Carcinoma, Squamous Cell; Carrier Proteins; Catechin; Cell Division; Cell Survival; Cells, Cultured; Epidermal Cells; Humans; Keratinocytes; Mitogen-Activated Protein Kinases; Models, Biological; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Skin Neoplasms; Tumor Cells, Cultured | 2003 |
Inhibitory effects of (-)-epigallocatechin gallate on the mutation, DNA strand cleavage, and DNA adduct formation by heterocyclic amines.
Topics: Animals; Camellia sinensis; Catechin; DNA Adducts; DNA Damage; Drosophila; Heterocyclic Compounds; Hot Temperature; Imidazoles; Mutagenesis; Mutagens; Plant Extracts; Plant Leaves; Quinolines | 2003 |
Effects of delayed administration of (-)-epigallocatechin gallate, a green tea polyphenol on the changes in polyamine levels and neuronal damage after transient forebrain ischemia in gerbils.
Topics: Animals; Antioxidants; Brain Chemistry; Catechin; Cell Survival; Chromatography, High Pressure Liquid; Disease Models, Animal; Flavonoids; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Male; Phenols; Polyamines; Polymers; Prosencephalon; Time Factors | 2003 |
Inhibition of bladder tumor growth by the green tea derivative epigallocatechin-3-gallate.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Transitional Cell; Catechin; Dose-Response Relationship, Drug; Free Radical Scavengers; Rats; Rats, Inbred F344; Tea; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 2003 |
Epigallocatechin-3-gallate is a potent natural inhibitor of fatty acid synthase in intact cells and selectively induces apoptosis in prostate cancer cells.
Topics: Acetic Acid; Antineoplastic Agents; Apoptosis; Catechin; Cell Division; Enzyme Inhibitors; Epithelial Cells; fas Receptor; Fatty Acid Synthases; Fibroblasts; Humans; Male; Prostatic Neoplasms; Tea; Tumor Cells, Cultured | 2003 |
Epigallocatechin gallate prevents autoimmune diabetes induced by multiple low doses of streptozotocin in mice.
Topics: Animals; Blood Glucose; Catechin; Cell Survival; Diabetes Mellitus, Type 1; Male; Mice; Mice, Inbred C57BL; Streptozocin | 2003 |
Green tea polyphenol causes differential oxidative environments in tumor versus normal epithelial cells.
Topics: Antioxidants; Bromodeoxyuridine; Catalase; Catechin; Epithelial Cells; Flavonoids; Humans; Neoplasms; Oxidative Stress; Phenols; Polymers; Reactive Oxygen Species; Superoxide Dismutase; Tea; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2003 |
Are histones the targets for flavan-3-ols (catechins) in nuclei?
Topics: Catechin; Cell Nucleus; Cells, Cultured; Chromatin; Chromosomes; DNA; Flavonoids; Histocytochemistry; Histones; Hydrogen-Ion Concentration; Mathematics; Mitosis; Spectrum Analysis; Titrimetry; Tsuga | 2003 |
Green tea-induced asthma: relationship between immunological reactivity, specific and non-specific bronchial responsiveness.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Catechin; Female; Food-Processing Industry; Humans; Male; Methacholine Chloride; Middle Aged; Molecular Weight; Occupational Diseases; Occupational Exposure; Protease Inhibitors; Skin; Skin Tests; Tea | 2003 |
Epigallocatechin-3-gallate inhibits activation of HER-2/neu and downstream signaling pathways in human head and neck and breast carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Blotting, Western; Breast Neoplasms; Carcinoma; Catechin; Cell Division; Cell Line, Tumor; Cyclin D1; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Genes, Reporter; Head and Neck Neoplasms; Humans; Immunoblotting; Luciferases; Paclitaxel; Phosphorylation; Prognosis; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Receptor, ErbB-2; Signal Transduction; Time Factors | 2003 |
Comparative study of the antioxidant effect of ardisin and epigallocatechin gallate in rat hepatocytes exposed to benomyl and 1-nitropyrene.
Topics: Animals; Antioxidants; Benomyl; Catechin; Cell Survival; Cells, Cultured; Culture Media; Fungicides, Industrial; Glutathione Peroxidase; Glutathione Reductase; Hepatocytes; Male; Malondialdehyde; Proteins; Pyrenes; Rats; Rats, Wistar; Resorcinols | 2003 |
Inhibition of lipoxygenase by (-)-epigallocatechin gallate: X-ray analysis at 2.1 A reveals degradation of EGCG and shows soybean LOX-3 complex with EGC instead.
Topics: Animals; Catechin; Crystallography, X-Ray; Glycine max; Humans; Hydrogen Bonding; Iron; Lipoxygenase Inhibitors; Models, Chemical; Models, Molecular; Oxygen; Protein Binding; Rabbits; Water | 2003 |
Dietary flavonoids modulate PCB-induced oxidative stress, CYP1A1 induction, and AhR-DNA binding activity in vascular endothelial cells.
Topics: Animals; Catechin; Cells, Cultured; Cytochrome P-450 CYP1A1; DNA; Endothelial Cells; Enzyme Induction; Flavonoids; Oxidative Stress; Polychlorinated Biphenyls; Protein Binding; Pulmonary Artery; Quercetin; Receptors, Aryl Hydrocarbon; Swine | 2003 |
Tea catechins protect against lead-induced ROS formation, mitochondrial dysfunction, and calcium dysregulation in PC12 cells.
Topics: Animals; Calcium; Catechin; Cell Death; Cell Survival; Dose-Response Relationship, Drug; Lead; Membrane Potentials; Mitochondria; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Tea | 2003 |
[Comparative vitamin P activity of tea catechins, of grape tannins and of buckwheat rutin].
Topics: Catechin; Catechols; Fagopyrum; Flavonoids; Fruit; Humans; Rutin; Tannins; Tea; Triticum; Vitamins; Vitis | 1954 |
Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites.
Topics: Animals; Catechin; Cell Line; Dogs; Drug Resistance, Multiple; Multidrug Resistance-Associated Proteins | 2003 |
Green tea epigallocatechin-3-gallate is an inhibitor of mammalian histidine decarboxylase.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Enzyme Inhibitors; Histamine; Histidine Decarboxylase; In Vitro Techniques; Rats; Recombinant Proteins; Tea; Tumor Cells, Cultured | 2003 |
EGCG corrects aberrant splicing of IKAP mRNA in cells from patients with familial dysautonomia.
Topics: Base Sequence; Carrier Proteins; Catechin; Cell Line; Drug Synergism; Dysautonomia, Familial; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Humans; Molecular Sequence Data; Mutation; RNA Splicing; RNA, Messenger; Tocotrienols; Transcriptional Elongation Factors | 2003 |
Membrane-rigidifying effects of anti-cancer dietary factors.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apigenin; Catechin; Cell Division; Cell Membrane; Diet; Flavonoids; Fluorescence Polarization; Genistein; Isoflavones; Liposomes; Membrane Fluidity; Membrane Lipids; Mice; Multiple Myeloma; Phenols; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2002 |
Evaluation of the NO scavenging activity of procyanidin in grape seed by use of the TMA-PTIO/NOC 7 ESR system.
Topics: Biflavonoids; Catechin; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Nitric Oxide; Proanthocyanidins; Seeds; Vitis | 2003 |
(-)-Epigallocatechin gallate causes oxidative damage to isolated and cellular DNA.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Antioxidants; Catechin; Chelating Agents; Deoxyguanosine; DNA; DNA Damage; Free Radical Scavengers; HL-60 Cells; Humans; Oxidation-Reduction; Phosphorus Radioisotopes | 2003 |
Development of collagenase-resistant collagen and its interaction with adult human dermal fibroblasts.
Topics: Actin Cytoskeleton; Biocompatible Materials; Catechin; Cell Adhesion; Cell Division; Cells, Cultured; Collagen; Collagenases; Culture Techniques; Fibroblasts; Humans; Macrophages; Male; Matrix Metalloproteinase 1; Middle Aged; Protein Conformation; Skin; Skin Physiological Phenomena; Structure-Activity Relationship; Temperature; Tissue Engineering | 2003 |
Roles of catalase and hydrogen peroxide in green tea polyphenol-induced chemopreventive effects.
Topics: Acetylcysteine; Caspase 3; Caspases; Catalase; Catechin; Cell Division; Cell Survival; Chemoprevention; Drug Combinations; Enzyme Activation; Flavonoids; Free Radical Scavengers; Humans; Hydrogen Peroxide; Phenols; Polyphenols; Reactive Oxygen Species; Superoxide Dismutase; Tea; Tumor Cells, Cultured | 2004 |
A combination effect of epigallocatechin gallate, a major compound of green tea catechins, with antibiotics on Helicobacter pylori growth in vitro.
Topics: Amoxicillin; Anti-Bacterial Agents; Catechin; Clarithromycin; Colony Count, Microbial; Drug Combinations; Drug Resistance, Bacterial; Drug Synergism; Helicobacter pylori; Metronidazole; Microbial Sensitivity Tests | 2003 |
Green tea polyphenol (-)-epigallocatechin gallate prevents oxidative damage on periventricular white matter of infantile rats with hydrocephalus.
Topics: Animals; Animals, Newborn; Brain; Catechin; Cerebral Ventricles; Hydrocephalus; Kaolin; Lipid Peroxidation; Malondialdehyde; Neuroprotective Agents; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Tea | 2003 |
Medulloblastoma cell invasion is inhibited by green tea (-)epigallocatechin-3-gallate.
Topics: Apoptosis; Caspase 3; Caspases; Catechin; Cell Adhesion; Cell Line, Tumor; Cell Movement; Collagen; Flow Cytometry; Humans; Integrin beta1; Medulloblastoma; Neoplasm Invasiveness; Tea; Up-Regulation | 2003 |
The galloyl moiety of green tea catechins is the critical structural feature to inhibit fatty-acid synthase.
Topics: Animals; Catechin; Chickens; Fatty Acid Synthases; Flavonoids; Humans; Kinetics; Phenols; Polyphenols; Structure-Activity Relationship; Tea | 2003 |
Green tea polyphenol epigallocatechin-3-gallate (EGCG) differentially inhibits interleukin-1 beta-induced expression of matrix metalloproteinase-1 and -13 in human chondrocytes.
Topics: Antioxidants; Cartilage; Catechin; Cells, Cultured; Chondrocytes; Collagenases; Down-Regulation; Drug Interactions; Flavonoids; Humans; Interleukin-1; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; NF-kappa B; Phenols; Polyphenols; RNA, Messenger; Tea; Tissue Inhibitor of Metalloproteinase-1; Transcription Factor AP-1 | 2004 |
Epigallocatechin gallate modulates CYP450 isoforms in the female Swiss-Webster mouse.
Topics: Animals; Antineoplastic Agents, Phytogenic; Catechin; Catechol O-Methyltransferase; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Female; Injections, Intraperitoneal; Kidney; Liver; Longevity; Mice; Necrosis; Ovary; Protein Isoforms | 2003 |
Oxidation of indole-3-acetic acid by horseradish peroxidase induces apoptosis in G361 human melanoma cells.
Topics: Antioxidants; Apoptosis; Ascorbic Acid; Caspases; Catechin; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Free Radicals; Horseradish Peroxidase; Humans; Indoleacetic Acids; JNK Mitogen-Activated Protein Kinases; Melanoma; Mitochondria; Mitogen-Activated Protein Kinases; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Prodrugs; Proteins | 2004 |
Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity by 1,2,3,4,6-penta-O-galloyl-beta-D-glucose in murine macrophage cells.
Topics: Acetophenones; Animals; Catechin; Cell Line; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Gallic Acid; Humans; Hydrolyzable Tannins; Isoenzymes; Leukemia, Erythroblastic, Acute; Lipopolysaccharides; Macrophages; Medicine, Chinese Traditional; Membrane Proteins; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Paeonia; Plant Extracts; Plant Roots; Prostaglandin-Endoperoxide Synthases; Pyrogallol; Structure-Activity Relationship; Tannins | 2003 |
Epigallocatechin gallate, the main component of tea polyphenol, binds to CD4 and interferes with gp120 binding.
Topics: Antibodies, Monoclonal; Antiviral Agents; Catechin; CD4 Antigens; Cells, Cultured; Endocytosis; Flavonoids; HIV Envelope Protein gp120; Humans; Leukemia; Phenols; Polyphenols; T-Lymphocytes; Tea | 2003 |
Enzyme induction and dietary chemicals as approaches to cancer chemoprevention: the Seventh DeWitt S. Goodman Lecture.
Topics: Animals; Anticarcinogenic Agents; Caffeine; Catechin; Chemoprevention; Curcumin; Enzyme Induction; Enzyme Inhibitors; Humans; Neoplasms | 2003 |
Mechanisms of the inhibitory effects of epigallocatechin-3 gallate on platelet-derived growth factor-BB-induced cell signaling and mitogenesis.
Topics: Becaplermin; Catechin; Cell Division; Cells, Cultured; Humans; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Signal Transduction | 2004 |
Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.
Topics: Adaptor Proteins, Signal Transducing; Anticarcinogenic Agents; Antineoplastic Agents; Carcinoma, Squamous Cell; Carrier Proteins; Catechin; Cell Division; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, p16; Humans; Models, Molecular; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; O(6)-Methylguanine-DNA Methyltransferase; Receptors, Retinoic Acid | 2003 |
Tea polyphenols inhibit the transport of dietary phenolic acids mediated by the monocarboxylic acid transporter (MCT) in intestinal Caco-2 cell monolayers.
Topics: Biological Transport; Caco-2 Cells; Catechin; Cell Membrane Permeability; Epithelial Cells; Flavonoids; Fluorescein; Fluorescent Dyes; Humans; Hydroxybenzoates; Intestinal Absorption; Intestinal Mucosa; Intestines; Monocarboxylic Acid Transporters; Phenols; Polyphenols; Tea | 2003 |
Heat-epimerized tea catechins rich in gallocatechin gallate and catechin gallate are more effective to inhibit cholesterol absorption than tea catechins rich in epigallocatechin gallate and epicatechin gallate.
Topics: Animals; Catechin; Cholesterol; Hot Temperature; Intestinal Absorption; Male; Micelles; Rats; Rats, Sprague-Dawley; Solubility; Tea | 2003 |
A constituent of green tea, epigallocatechin-3-gallate, activates endothelial nitric oxide synthase by a phosphatidylinositol-3-OH-kinase-, cAMP-dependent protein kinase-, and Akt-dependent pathway and leads to endothelial-dependent vasorelaxation.
Topics: Animals; Aorta; Blotting, Western; Catechin; Cattle; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphorylation; Protease Inhibitors; Rats; Time Factors | 2004 |
Epigallocatechin-3-gallate increases intracellular [Ca2+] in U87 cells mainly by influx of extracellular Ca2+ and partly by release of intracellular stores.
Topics: Calcium; Catechin; Enzyme Activation; Flufenamic Acid; Genistein; Inositol Phosphates; Ion Channels; Mefenamic Acid; ortho-Aminobenzoates; Protein-Tyrosine Kinases; Tea; Tumor Cells, Cultured; Type C Phospholipases | 2004 |
Epigallocatechin-3-gallate is absorbed but extensively glucuronidated following oral administration to mice.
Topics: Administration, Oral; Animals; Biological Availability; Catechin; Chromatography, High Pressure Liquid; Feces; Glucuronides; Injections, Intravenous; Male; Mice; Mice, Inbred Strains; Stomach; Tissue Distribution | 2003 |
[Effect of L-EGCG on lipopolysaccharide-induced glomerular mesangial cell proliferation in rats].
Topics: Animals; Apoptosis; Catechin; Cell Division; Cells, Cultured; Esters; Free Radical Scavengers; Glomerular Mesangium; Glomerulonephritis, Membranoproliferative; Lipopolysaccharides; Proliferating Cell Nuclear Antigen; Rats; Superoxide Dismutase | 2003 |
Green tea polyphenol epigallocatechin-3-gallate inhibits platelet-derived growth factor-induced proliferation of human hepatic stellate cell line LI90.
Topics: Antineoplastic Agents, Phytogenic; Becaplermin; Catechin; Cell Division; Cell Line, Tumor; Collagen Type I; Collagen Type IV; Humans; Liver; Liver Neoplasms; Phosphorylation; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Radioligand Assay; Receptors, Platelet-Derived Growth Factor; RNA, Messenger; Tea | 2004 |
Epigallocatechin-3-gallate, constituent of green tea, suppresses the LPS-induced phenotypic and functional maturation of murine dendritic cells through inhibition of mitogen-activated protein kinases and NF-kappaB.
Topics: Animals; Antigens, CD; B7-1 Antigen; B7-2 Antigen; Catechin; Cell Division; Dendritic Cells; Dose-Response Relationship, Drug; Endocytosis; Gene Expression; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Interleukin-12; Lipopolysaccharides; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; Phenotype; Tea | 2004 |
Essential role of caspases in epigallocatechin-3-gallate-mediated inhibition of nuclear factor kappa B and induction of apoptosis.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Carcinoma, Squamous Cell; Caspase Inhibitors; Caspases; Catechin; Cell Line, Tumor; Cell Nucleus; Cell Survival; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Male; Models, Biological; NF-kappa B; Oligopeptides; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Protein Structure, Tertiary; Time Factors; Transcription, Genetic | 2004 |
Induction of apoptosis by EGCG in selected tumour cell lines in vitro.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma; Catechin; Cell Line; Cell Line, Tumor; Comet Assay; Dose-Response Relationship, Drug; Humans; Neoplasms | 2003 |
Multiple effects of green tea catechin on the antifungal activity of antimycotics against Candida albicans.
Topics: Amphotericin B; Antifungal Agents; Candida albicans; Catechin; Colony Count, Microbial; Culture Media; Drug Synergism; Hydrogen-Ion Concentration; Microbial Sensitivity Tests | 2004 |
Epigallocatechin gallate can significantly decrease free oxygen radicals in the reperfusion injury in vivo.
Topics: Animals; Antioxidants; Catechin; Disease Models, Animal; Femoral Artery; Femoral Vein; Kinetics; Male; Muscle, Skeletal; Rats; Rats, Wistar; Reperfusion Injury; Superoxides | 2003 |
Epigallocatechin 3-gallate attenuates neuronal damage induced by 3-hydroxykynurenine.
Topics: Apoptosis; Caspase 3; Caspases; Catechin; Cell Survival; Dose-Response Relationship, Drug; Humans; Kynurenine; Neuroblastoma; Neurons; Neuroprotective Agents; Reactive Oxygen Species; Tumor Cells, Cultured | 2004 |
Vascular actions of the polyphenolic catechin gallate EGCG: endothelium-dependent contraction and relaxation.
Topics: Animals; Aorta, Thoracic; Catechin; Endothelium, Vascular; Enzyme Inhibitors; Female; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Norepinephrine; Nucleoside-Diphosphate Kinase | 2003 |
Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-Associated Death Protein; Carrier Proteins; Catechin; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Activation; ErbB Receptors; Female; Flavonoids; Flow Cytometry; Forkhead Box Protein O1; Forkhead Transcription Factors; HeLa Cells; Humans; Immunoblotting; In Situ Nick-End Labeling; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phenols; Phosphorylation; Polyphenols; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Tea; Time Factors; Transcription Factors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Uterine Cervical Neoplasms | 2004 |
Docking studies and model development of tea polyphenol proteasome inhibitors: applications to rational drug design.
Topics: Amides; Binding Sites; Camellia sinensis; Catechin; Chymotrypsin; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Drug Design; Flavonoids; Models, Molecular; Multienzyme Complexes; Phenols; Polyphenols; Proteasome Endopeptidase Complex; Protein Binding; Protein Subunits | 2004 |
Lipid raft-associated catechin suppresses the FcepsilonRI expression by inhibiting phosphorylation of the extracellular signal-regulated kinase1/2.
Topics: Antigens, CD; Basophils; beta-Cyclodextrins; Catechin; Cell Line; Cell Survival; Cholesterol; Cyclodextrins; Down-Regulation; Enzyme Inhibitors; Flow Cytometry; Gene Expression; Humans; Immunoblotting; Membrane Microdomains; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Receptors, IgE | 2004 |
Green tea polyphenol (-)-epigallocatechin-3-gallate protects rat PC12 cells from apoptosis induced by serum withdrawal independent of P13-Akt pathway.
Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; Catechin; Cell Survival; Culture Media, Serum-Free; Nerve Growth Factors; Neuroprotective Agents; PC12 Cells; Rats | 2003 |
Inhibitory effect of epigallocatechin 3-O-gallate on vascular smooth muscle cell hypertrophy induced by angiotensin II.
Topics: Angiotensin II; Animals; Cardiomegaly; Catechin; Cells, Cultured; Male; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth, Vascular; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction | 2004 |
Unravelling green tea's mechanisms of action: more than meets the eye.
Topics: Animals; Camellia sinensis; Catechin; Cytokines; Free Radicals; Humans; Matrix Metalloproteinase Inhibitors; Signal Transduction | 2004 |
Inhibition of the vascular-endothelial growth factor-induced intracellular signaling and mitogenesis of human endothelial cells by epigallocatechin-3 gallate.
Topics: Catechin; Cell Division; Cells, Cultured; Endothelial Cells; Growth Inhibitors; Humans; Mitogens; Second Messenger Systems; Vascular Endothelial Growth Factor A | 2004 |
Green tea metabolite EGCG protects membranes against oxidative damage in vitro.
Topics: Adenosine Triphosphatases; Antineoplastic Agents, Phytogenic; Antioxidants; Catechin; Erythrocyte Membrane; Humans; Lipid Peroxidation; Molecular Structure; Oxidation-Reduction; Plant Extracts; Tea; Thiobarbituric Acid Reactive Substances | 2004 |
Theasinensin A, a tea polyphenol formed from (-)-epigallocatechin gallate, suppresses antibiotic resistance of methicillin-resistant Staphylococcus aureus.
Topics: Anti-Infective Agents; Benzopyrans; Catechin; Humans; Methicillin Resistance; Microbial Sensitivity Tests; Phenols; Phytotherapy; Plant Extracts; Staphylococcus aureus; Tea | 2003 |
Oxidative coupling of epigallocatechin gallate amplifies antioxidant activity and inhibits xanthine oxidase activity.
Topics: Antioxidants; Catechin; Free Radical Scavengers; Humans; Inhibitory Concentration 50; Molecular Structure; Oxidation-Reduction; Superoxides; Xanthine; Xanthine Oxidase | 2004 |
[Role of p38MAPKs pathway in the growth inhibition of rabbit lens epithelial cells induced by EGCG].
Topics: Animals; Catechin; Cell Division; Epithelial Cells; Lens, Crystalline; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rabbits | 2003 |
Modulation of phosphatidylinositol-3-kinase/protein kinase B- and mitogen-activated protein kinase-pathways by tea polyphenols in human prostate cancer cells.
Topics: Antineoplastic Agents; Biflavonoids; Catechin; Humans; Male; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Tea; Tumor Cells, Cultured | 2004 |
Green tea polyphenol (-)-epigallocatechin gallate attenuates the neuronal NADPH-d/nNOS expression in the nodose ganglion of acute hypoxic rats.
Topics: Animals; Antioxidants; Catechin; Dose-Response Relationship, Drug; Down-Regulation; Flavonoids; Hypoxia, Brain; Immunohistochemistry; Male; NADPH Dehydrogenase; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nodose Ganglion; Oxidative Stress; Phenols; Polyphenols; Rats; Rats, Wistar; Time Factors | 2004 |
The tea polyphenol, (-)-epigallocatechin gallate effects on growth, apoptosis, and telomerase activity in cervical cell lines.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Division; Cell Line; Cervix Uteri; Female; Humans; Tea; Telomerase; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 2004 |
Growth inhibition of prostate cancer cells by epigallocatechin gallate in the presence of Cu2+.
Topics: Adenoma; Catechin; Cell Division; Cell Survival; Copper; Free Radicals; Humans; Luminescent Measurements; Male; Prostatic Neoplasms; Tumor Cells, Cultured | 2004 |
Inhibition of c-Jun NH2-terminal kinase activity improves ischemia/reperfusion injury in rat lungs.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Carrier Proteins; Catechin; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; L-Lactate Dehydrogenase; Lung; Male; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proteins; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Transcription Factor AP-1; Tumor Necrosis Factor-alpha; Up-Regulation | 2004 |
EGCG down-regulates telomerase in human breast carcinoma MCF-7 cells, leading to suppression of cell viability and induction of apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Breast Neoplasms; Catalytic Domain; Catechin; Cell Division; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Flow Cytometry; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Telomerase; Time Factors | 2004 |
Comparative study of the growth-inhibitory and apoptosis-inducing activities of black tea theaflavins and green tea catechin on murine myeloid leukemia cells.
Topics: Animals; Apoptosis; Biflavonoids; Catechin; Cell Division; Cell Line, Tumor; Female; Leukemia, Myeloid; Mice; Mice, Inbred BALB C; Tea; Tumor Stem Cell Assay | 2004 |
Telomere maintenance in childhood primitive neuroectodermal brain tumors.
Topics: Adolescent; Adult; Brain Neoplasms; Catechin; Cell Line, Tumor; Cell Survival; Child; Child, Preschool; DNA-Binding Proteins; Dose-Response Relationship, Drug; Female; Fetus; Humans; Infant; Male; Middle Aged; Neuroectodermal Tumors, Primitive; Telomerase; Telomere | 2004 |
Effect of green tea extract on the induction of ornithine decarboxylase and the activation of extracellular signal-regulated kinase in bladder carcinoma ECV304 cells.
Topics: Apoptosis; Caspases; Catechin; Cell Survival; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Humans; In Situ Nick-End Labeling; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Plant Extracts; Tea; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 2003 |
Inhibitory effect of green tea catechins on cysteine proteinases in Porphyromonas gingivalis.
Topics: Adhesins, Bacterial; Catechin; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Gingipain Cysteine Endopeptidases; Hemagglutinins; Humans; Plant Extracts; Porphyromonas gingivalis; Tea | 2004 |
Different susceptibilities of Staphylococcus and Gram-negative rods to epigallocatechin gallate.
Topics: Anti-Bacterial Agents; Catechin; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Phytotherapy; Staphylococcus; Tea | 2004 |
Treatment of epigallocatechin-3-gallate inhibits matrix metalloproteinases-2 and -9 via inhibition of activation of mitogen-activated protein kinases, c-jun and NF-kappaB in human prostate carcinoma DU-145 cells.
Topics: Antineoplastic Agents, Phytogenic; Blotting, Western; Catechin; Cell Line, Tumor; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Fibroblasts; Genes, jun; Humans; JNK Mitogen-Activated Protein Kinases; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; Prostatic Neoplasms | 2004 |
Role of hydrogen peroxide in bactericidal action of catechin.
Topics: Anti-Bacterial Agents; Catechin; Gram-Negative Aerobic Bacteria; Gram-Positive Bacteria; Hydrogen Peroxide; Hydrogen-Ion Concentration; Oxidants; Tea; Time Factors | 2004 |
VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; B-Lymphocytes; Catechin; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Phosphorylation; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2004 |
Inhibition of liver cancer cell proliferation and migration by a combination of (-)-epigallocatechin-3-gallate and ascorbic acid.
Topics: Antioxidants; Ascorbic Acid; Catechin; Cell Division; Cell Movement; Colony Count, Microbial; Culture Media; Drug Therapy, Combination; Humans; Liver Neoplasms; Reference Values; Sensitivity and Specificity; Tumor Cells, Cultured | 2003 |
Involvement of ERK AND p38 MAP kinase in AAPH-induced COX-2 expression in HaCaT cells.
Topics: Amidines; Catechin; Chromans; Cyclooxygenase 2; Dinoprostone; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Humans; Imidazoles; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Keratinocytes; MAP Kinase Kinase 4; Membrane Proteins; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Pyridines | 2004 |
Polyphenol (-)-epigallocatechin gallate inhibits apoptosis induced by irradiation in human HaCaT keratinocytes.
Topics: Apoptosis; Caspase 3; Caspases; Catechin; Cell Division; Cell Line; Humans; Keratinocytes; Poly(ADP-ribose) Polymerases | 2004 |
Cellular toxicity of catechin analogues containing gallate in opossum kidney proximal tubular (OK) cells.
Topics: Animals; Antioxidants; Apoptosis; Catechin; Cell Division; Cells, Cultured; DNA Fragmentation; Dose-Response Relationship, Drug; Gallic Acid; In Situ Nick-End Labeling; Kidney Tubules, Proximal; Opossums | 2004 |
A receptor for green tea polyphenol EGCG.
Topics: Anticarcinogenic Agents; Antioxidants; Binding Sites; Catechin; Kinetics; Receptors, Laminin; Substrate Specificity | 2004 |
Inhibitory effects of green tea polyphenols on the production of a virulence factor of the periodontal-disease-causing anaerobic bacterium Porphyromonas gingivalis.
Topics: Camellia sinensis; Catechin; Fatty Acids; Flavonoids; Humans; Periodontal Diseases; Phenols; Phenylacetates; Polyphenols; Porphyromonas gingivalis | 2004 |
Potent inhibitors of anthrax lethal factor from green tea.
Topics: Animals; Antigens, Bacterial; Apoptosis; Bacterial Toxins; Camellia sinensis; Catechin; Macrophages; Metalloproteases; Mitogen-Activated Protein Kinase Kinases; Rats; Rats, Inbred F344; Tea | 2004 |
Regulation of urokinase plasminogen activator by epigallocatechin-3-gallate in human fibrosarcoma cells.
Topics: Antineoplastic Agents, Phytogenic; Blotting, Northern; Blotting, Western; Catechin; Chloramphenicol O-Acetyltransferase; Fibrosarcoma; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Indicators and Reagents; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Phosphorylation; RNA, Messenger; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 2004 |
The tea flavonoid epigallocatechin-3-gallate reduces cytokine-induced VCAM-1 expression and monocyte adhesion to endothelial cells.
Topics: Catechin; Cell Adhesion; Cell Line; Coculture Techniques; Cytokines; Dose-Response Relationship, Drug; E-Selectin; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; Monocytes; NF-kappa B; Reverse Transcriptase Polymerase Chain Reaction; Tea; Transcription, Genetic; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Cell Adhesion Molecule-1 | 2004 |
O-methylated catechins from tea leaves inhibit multiple protein kinases in mast cells.
Topics: Animals; Anti-Allergic Agents; Catechin; Enzyme Activation; Enzyme Inhibitors; Mast Cells; Methylation; Mice; Mice, Inbred CBA; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Passive Cutaneous Anaphylaxis; Plant Leaves; Protein Kinase C; Protein Kinase C beta; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Signal Transduction; Tea | 2004 |
Green tea polyphenol epigallocatechin-3-gallate protects HepG2 cells against CYP2E1-dependent toxicity.
Topics: Arachidonic Acid; Carcinoma, Hepatocellular; Catalysis; Catechin; Cell Line, Tumor; Cytochrome P-450 CYP2E1; Glutathione; Hepatocytes; Humans; Iron; Lipid Peroxidation; Mitochondria; Phenols; Protective Agents; Reactive Oxygen Species; Tea | 2004 |
Green tea polyphenol and curcumin inversely regulate human involucrin promoter activity via opposing effects on CCAAT/enhancer-binding protein function.
Topics: Antioxidants; Binding Sites; Catechin; CCAAT-Enhancer-Binding Proteins; Cell Differentiation; Curcumin; Cysteine Endopeptidases; DNA; Enzyme Activation; Flavonoids; Humans; Keratinocytes; MAP Kinase Kinase 3; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinase 13; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Mutation; Phenols; Polyphenols; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Protein Precursors; Protein-Tyrosine Kinases; Tea; Transcription Factor CHOP; Transcription Factors | 2004 |
Activity of (-)-epigallocatechin 3-O-gallate against oxidative stress in rats with adenine-induced renal failure.
Topics: Adenine; Animals; Antioxidants; Blood Urea Nitrogen; Catechin; Creatinine; Hydroxyl Radical; Kidney Failure, Chronic; Male; Methylguanidine; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar | 2004 |
Determination of (-)-epigallocatechin gallate in rat blood by microdialysis coupled with liquid chromatography.
Topics: Animals; Catechin; Chromatography, High Pressure Liquid; Microdialysis; Rats; Reproducibility of Results | 2004 |
A dosage design of mitomycin C tablets containing finely powdered green tea.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Carcinoma, Ehrlich Tumor; Catechin; Cell Line, Tumor; Drug Combinations; Drug Compounding; Drug Delivery Systems; Hardness; Mitomycin; Powders; Pressure; Tablets; Tea; Time Factors | 2004 |
Inhibition of fucosyltransferase VII by gallic acid and its derivatives.
Topics: Catechin; Ellagic Acid; Enzymes; Fucosyltransferases; Gallic Acid; Humans; Manganese | 2004 |
Epigallocatechin gallate markedly enhances formation of 8-oxo-7,8-dihydro-2'-deoxyguanosine in the reaction of 2'-deoxyguanosine with hypochlorous acid.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Catechin; Deoxyguanosine; DNA; Free Radical Scavengers; Free Radicals; Hypochlorous Acid; Molecular Structure; Oxidation-Reduction; Peroxides | 2004 |
(-)-Epigallocatechin-3-gallate induces contraction of the rat aorta by a calcium influx-dependent mechanism.
Topics: Animals; Antioxidants; Aorta; Azlocillin; Calcium; Catechin; Drug Synergism; Imidazolidines; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred WKY; Thapsigargin; Vasoconstriction; Vasodilator Agents | 2004 |
[MDR-reversing effect of two components of catechin on human hepatocellular carcinoma BEL-7404/Adr in vitro].
Topics: Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Liver Neoplasms | 2004 |
(-)-Epigallocatechin-3-gallate and hinokitiol reduce melanin synthesis via decreased MITF production.
Topics: Animals; Catechin; Cell Line; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Combinations; Humans; Melanins; Mice; Microphthalmia-Associated Transcription Factor; Monoterpenes; Transcription Factors; Tropolone | 2004 |
Generation of hydrogen peroxide primarily contributes to the induction of Fe(II)-dependent apoptosis in Jurkat cells by (-)-epigallocatechin gallate.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Catalase; Catechin; HeLa Cells; HL-60 Cells; Humans; Hydrogen Peroxide; Iron; Jurkat Cells; Oxidants; Oxidation-Reduction; Phenanthrolines; Reactive Oxygen Species; U937 Cells; Urokinase-Type Plasminogen Activator | 2004 |
Interaction of catechins with aluminum in vitro.
Topics: Acetic Acid; Aluminum; Buffers; Catechin; Flavonoids; Fluorides; Hydrogen-Ion Concentration; Molecular Structure; Phenols; Plant Extracts; Plant Leaves; Polyphenols; Spectrum Analysis; Tea | 2004 |
Pigments in green tea leaves (Camellia sinensis) suppress transformation of the aryl hydrocarbon receptor induced by dioxin.
Topics: Camellia sinensis; Catechin; Chlorophyll; Flavonoids; Lutein; Phenols; Pigments, Biological; Plant Extracts; Plant Leaves; Polychlorinated Dibenzodioxins; Polyphenols; Receptors, Aryl Hydrocarbon | 2004 |
Epigallocatechin-3-gallate, a green tea-derived polyphenol, inhibits IL-1 beta-dependent proinflammatory signal transduction in cultured respiratory epithelial cells.
Topics: Anti-Inflammatory Agents; Catechin; Cell Line, Tumor; Enzyme Activation; Flavonoids; Gene Expression Regulation; Humans; I-kappa B Kinase; Inflammation Mediators; Interleukin-1; Interleukin-1 Receptor-Associated Kinases; Interleukin-8; Isoenzymes; NF-kappa B; Phenols; Phosphorylation; Polyphenols; Protein Kinases; Protein Serine-Threonine Kinases; Respiratory Mucosa; Signal Transduction; Tea; Transcription Factor RelA | 2004 |
Modulation of beta-lactam resistance in Staphylococcus aureus by catechins and gallates.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; Catechin; Flavonoids; Gallic Acid; Microbial Sensitivity Tests; Oxacillin; Phenols; Polyphenols; Propyl Gallate; Staphylococcus aureus | 2004 |
Evaluation of epigallocatechin gallate and related plant polyphenols as inhibitors of the FabG and FabI reductases of bacterial type II fatty-acid synthase.
Topics: Acetyltransferases; Alcohol Oxidoreductases; Anti-Bacterial Agents; Catechin; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Fatty Acid Synthase, Type II; Flavonoids; Molecular Structure; Multienzyme Complexes; Oxidoreductases; Phenols; Polyphenols; Tea | 2004 |
Activation of the Akt/nuclear factor-kappaB signaling axis in developing lung neoplasia.
Topics: Anticarcinogenic Agents; Budesonide; Catechin; Cell Line, Tumor; Eflornithine; Humans; Lung Neoplasms; Neoplasm Proteins; NF-kappa B; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt | 2004 |
Differential effects of green tea-derived catechin on developing versus established atherosclerosis in apolipoprotein E-null mice.
Topics: Animals; Antioxidants; Apolipoproteins E; Arteriosclerosis; Camellia sinensis; Carotid Artery Diseases; Catechin; Cell Division; Cholesterol; Disease Progression; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Transcription Factor AP-1 | 2004 |
Growth inhibition and cell cycle arrest effects of epigallocatechin gallate in the NBT-II bladder tumour cell line.
Topics: Antineoplastic Agents, Phytogenic; Camellia sinensis; Catechin; Cell Cycle; Cell Division; Cell Line, Tumor; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Phytotherapy; Reverse Transcriptase Polymerase Chain Reaction; Urinary Bladder Neoplasms | 2004 |
In vivo reversal of doxorubicin resistance by (-)-epigallocatechin gallate in a solid human carcinoma xenograft.
Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Catechin; Doxorubicin; Drug Resistance, Neoplasm; Humans; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Transplantation, Heterologous | 2004 |
Interference effect of epigallocatechin-3-gallate on targets of nuclear factor kappaB signal transduction pathways activated by EB virus encoded latent membrane protein 1.
Topics: Active Transport, Cell Nucleus; Antineoplastic Agents; Catechin; Cell Line, Tumor; Cell Survival; ErbB Receptors; Humans; I-kappa B Proteins; Nasopharyngeal Neoplasms; NF-kappa B; NF-KappaB Inhibitor alpha; Promoter Regions, Genetic; Signal Transduction; Transcription Factor RelA; Viral Matrix Proteins | 2004 |
Involvement of ROS and JNK1 in selenite-induced apoptosis in Chang liver cells.
Topics: Acetylcysteine; Anthracenes; Apoptosis; Catechin; Cell Line; DNA Fragmentation; Free Radical Scavengers; Humans; Liver; Mitogen-Activated Protein Kinase 8; Phosphorylation; Reactive Oxygen Species; Selenium; Signal Transduction | 2004 |
Epigallocatechin-gallate enhances the activity of tetracycline in staphylococci by inhibiting its efflux from bacterial cells.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Catechin; Drug Synergism; Membrane Proteins; Microbial Sensitivity Tests; Spectrometry, Fluorescence; Staphylococcus; Staphylococcus aureus; Staphylococcus epidermidis; Tetracycline; Tetracycline Resistance | 2004 |
Direct inhibition of the ubiquitin-proteasome pathway by ester bond-containing green tea polyphenols is associated with increased expression of sterol regulatory element-binding protein 2 and LDL receptor.
Topics: Camellia sinensis; Catechin; Cysteine Endopeptidases; DNA-Binding Proteins; Esters; HeLa Cells; Humans; Multienzyme Complexes; Proteasome Endopeptidase Complex; Receptors, LDL; Sterol Regulatory Element Binding Protein 2; Transcription Factors; Ubiquitin | 2004 |
(-)-Epigallocatechin gallate inhibits membrane-type 1 matrix metalloproteinase, MT1-MMP, and tumor angiogenesis.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Catechin; Cell Division; Cell Movement; Colonic Neoplasms; Endothelium, Vascular; Humans; Matrix Metalloproteinase 14; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Methylcholanthrene; Mice; Neovascularization, Pathologic; Sarcoma, Experimental; Tumor Cells, Cultured; Umbilical Veins; Urokinase-Type Plasminogen Activator | 2004 |
Protective effects of green tea catechins on cerebral ischemic damage.
Topics: Animals; Brain Ischemia; Catechin; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Granulocyte Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Infarction, Middle Cerebral Artery; Interleukin-3; Male; Malondialdehyde; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Plant Extracts; Rats; Rats, Wistar; Recombinant Fusion Proteins; Recombinant Proteins; Tea; Tyrosine | 2004 |
Study of the combined effect of X-irradiation and epigallocatechin-gallate (a tea component) on the growth inhibition and induction of apoptosis in human cancer cell lines.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Survival; HeLa Cells; Humans; K562 Cells; Multiple Myeloma; X-Rays | 2004 |
Epigallocatechin gallate attenuates adhesion and migration of CD8+ T cells by binding to CD11b.
Topics: Antigens, CD1; Catechin; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Movement; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Granulocytes; Humans; Integrins; Monocytes | 2004 |
Phospholipase D isozymes mediate epigallocatechin gallate-induced cyclooxygenase-2 expression in astrocyte cells.
Topics: 1-Butanol; Animals; Astrocytes; Astrocytoma; Blotting, Western; Carbazoles; Catechin; Cell Line, Tumor; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Isoenzymes; Membrane Proteins; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphatidic Acids; Phospholipase D; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protein Isoforms; Protein Kinase C; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Transfection | 2004 |
In vitro effects of the polyphenols resveratrol, mangiferin and (-)-epigallocatechin-3-gallate on the scuticociliate fish pathogen Philasterides dicentrarchi.
Topics: Analysis of Variance; Animals; Antiprotozoal Agents; Catechin; Dose-Response Relationship, Drug; Fish Diseases; Flatfishes; In Vitro Techniques; Oligohymenophorea; Protozoan Infections, Animal; Resveratrol; Stilbenes; Xanthones | 2004 |
Inhibitory effect(s) of polymeric black tea polyphenol fractions on the formation of [(3)H]-B(a)P-derived DNA adducts.
Topics: Animals; Benzo(a)pyrene; Camellia sinensis; Catechin; Cytochrome P-450 Enzyme System; DNA Adducts; Flavonoids; Male; Microsomes, Liver; Oxazines; Phenols; Plant Leaves; Polyphenols; Rats; Rats, Sprague-Dawley; Tritium | 2004 |
(-)-Epigallocatechin-3-gallate protects cultured spiral ganglion cells from H2O2-induced oxidizing damage.
Topics: Animals; Antioxidants; Apoptosis; Catechin; Cell Survival; Cells, Cultured; Gene Expression; Hydrogen Peroxide; Mice; Oxidation-Reduction; Reverse Transcriptase Polymerase Chain Reaction; Spiral Ganglion; Superoxide Dismutase; Up-Regulation | 2004 |
Green tea polyphenol (-)-epigallocatechin gallate blocks epithelial barrier dysfunction provoked by IFN-gamma but not by IL-4.
Topics: Adjuvants, Immunologic; Catechin; Cell Line; DNA-Binding Proteins; Escherichia coli; Flavonoids; Humans; Immunosuppressive Agents; Interferon-gamma; Interleukin-4; Intestinal Mucosa; Permeability; Phenols; Polyphenols; STAT1 Transcription Factor; STAT6 Transcription Factor; Tea; Trans-Activators | 2004 |
Inhibitory effect of (-)-epigallocatechin 3-gallate, a polyphenol of green tea, on neutrophil chemotaxis in vitro and in vivo.
Topics: Animals; Camellia sinensis; Catechin; Chemokine CXCL1; Chemokines; Chemokines, CXC; Chemotaxis, Leukocyte; Inflammation; Intercellular Signaling Peptides and Proteins; Male; Neutrophils; Rats; Rats, Wistar | 2004 |
The use of comet assay data with a simple reaction mechanism to evaluate the relative effectiveness of free radical scavenging by quercetin, epigallocatechin gallate and N-acetylcysteine in UV-irradiated MRC5 lung fibroblasts.
Topics: Acetylcysteine; Catechin; Cells, Cultured; Comet Assay; DNA; DNA Damage; Fibroblasts; Free Radical Scavengers; Humans; Quercetin; Ultraviolet Rays | 2004 |
Prooxidant property of green tea polyphenols epicatechin and epigallocatechin-3-gallate: implications for anticancer properties.
Topics: Animals; Antineoplastic Agents; Antioxidants; Catechin; Cattle; Chemoprevention; Copper; DNA; Oxidation-Reduction; Plant Extracts; Plant Leaves; Reactive Oxygen Species; Tea | 2004 |
Inhibitory Effects of the C-2 Epimeric Isomers of Tea Catechins on Mouse Type IV Allergy.
Topics: Animals; Anti-Allergic Agents; Catechin; Dermatitis, Contact; Isomerism; Male; Mice; Mice, Inbred ICR; Oxazolone; Tea | 2004 |
Transcriptional responses to epigallocatechin-3 gallate in HT 29 colon carcinoma spheroids.
Topics: Blotting, Western; Catechin; Colonic Neoplasms; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins c-fos; ras GTPase-Activating Proteins; RNA, Messenger | 2004 |
Mechanisms of inhibition of tumor angiogenesis and vascular tumor growth by epigallocatechin-3-gallate.
Topics: Animals; Apoptosis; Capillaries; Catechin; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Nude; Neovascularization, Pathologic; NIH 3T3 Cells; Plant Preparations; Sarcoma, Kaposi; Tea; Vascular Neoplasms; Xenograft Model Antitumor Assays | 2004 |
Hypoxia-inducible factor 1alpha- mediated resistance to phenolic anticancer.
Topics: Animals; Antineoplastic Agents; Antioxidants; Blotting, Western; Capsaicin; Catechin; Cell Line, Tumor; Cell Survival; DNA-Binding Proteins; Drug Resistance, Neoplasm; Hypoxia-Inducible Factor 1; Nuclear Proteins; Resveratrol; Stilbenes; Time Factors; Transcription Factors; Transfection | 2004 |
Piperine enhances the bioavailability of the tea polyphenol (-)-epigallocatechin-3-gallate in mice.
Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Benzodioxoles; Biological Availability; Catechin; Cells, Cultured; Enzyme Inhibitors; Humans; Male; Mice; Microsomes, Liver; Piperidines; Polyunsaturated Alkamides | 2004 |
Phosphatidylinositol-3 kinase/Akt and GSK-3 mediated cytoprotective effect of epigallocatechin gallate on oxidative stress-injured neuronal-differentiated N18D3 cells.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Blotting, Western; Caspase Inhibitors; Catechin; Cell Differentiation; Cell Line; Cell Survival; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Hydrogen Peroxide; Mice; Mice, Inbred BALB C; Neurons; Neuroprotective Agents; Oncogene Protein v-akt; Oxidants; Oxidative Stress; Phosphatidylinositol 3-Kinases; Retroviridae Proteins, Oncogenic; Signal Transduction | 2004 |
Component in green tea helps kill leukemia cells.
Topics: Antineoplastic Agents, Phytogenic; Catechin; Drug Screening Assays, Antitumor; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Tea | 2004 |
Inhibition of interleukin-1beta-stimulated collagenase and stromelysin expression in human tendon fibroblasts by epigallocatechin gallate ester.
Topics: Catechin; Collagenases; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Interleukin-1; Matrix Metalloproteinase 3; Mitogen-Activated Protein Kinase 10; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; RNA, Messenger; Signal Transduction; Tendons | 2004 |
(-)-Epigallocatechin gallate attenuates glutamate-induced cytotoxicity via intracellular Ca modulation in PC12 cells.
Topics: Animals; Calcium; Catechin; Cell Death; Cell Survival; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Intracellular Fluid; PC12 Cells; Rats | 2004 |
Protective effect of epigallocatechin gallate on brain damage after transient middle cerebral artery occlusion in rats.
Topics: Animals; Catechin; Hypoxia, Brain; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2004 |
Antioxidants regulate normal human keratinocyte differentiation.
Topics: Anticarcinogenic Agents; Catechin; CCAAT-Enhancer-Binding Proteins; Cell Differentiation; Curcumin; Drug Interactions; Humans; Keratinocytes; Mitogen-Activated Protein Kinase 13; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Protein Precursors; Tea | 2004 |
Phospholipase C, protein kinase C, Ca2+/calmodulin-dependent protein kinase II, and redox state are involved in epigallocatechin gallate-induced phospholipase D activation in human astroglioma cells.
Topics: Antineoplastic Agents; Antioxidants; Astrocytoma; Brain Neoplasms; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Catechin; Cell Line, Tumor; Enzyme Activation; Enzyme Inhibitors; Humans; Oxidation-Reduction; Phospholipase C gamma; Phospholipase D; Protein Kinase C; Reactive Oxygen Species; Tea; Type C Phospholipases | 2004 |
Green tea (Camellia sinensis) extract does not alter cytochrome p450 3A4 or 2D6 activity in healthy volunteers.
Topics: Administration, Oral; Adult; Alprazolam; Camellia sinensis; Capsules; Catechin; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dextromethorphan; Dietary Supplements; Drug Administration Schedule; Female; Half-Life; Humans; Male; Plant Extracts; Plant Leaves; Time Factors | 2004 |
Epigallocatechin-3-gallate inhibits STAT-1 activation and protects cardiac myocytes from ischemia/reperfusion-induced apoptosis.
Topics: Administration, Oral; Animals; Animals, Newborn; Apoptosis; Caspases; Catechin; Cell Survival; Cells, Cultured; DNA-Binding Proteins; Enzyme Activation; Heart; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Phosphorylation; Plant Extracts; Rats; Reperfusion Injury; STAT1 Transcription Factor; Tea; Trans-Activators | 2004 |
Green tea polyphenols prevent toxin-induced hepatotoxicity in mice by down-regulating inducible nitric oxide-derived prooxidants.
Topics: Animals; Antioxidants; Blotting, Western; Carbon Tetrachloride; Catechin; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation, Enzymologic; Immunohistochemistry; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred ICR; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Random Allocation; RNA, Messenger; Severity of Illness Index; Tea | 2004 |
Direct evidence of interaction of a green tea polyphenol, epigallocatechin gallate, with lipid bilayers by solid-state Nuclear Magnetic Resonance.
Topics: Catechin; Deuterium; Dimyristoylphosphatidylcholine; Flavonoids; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phenols; Polyphenols; Tea | 2004 |
Epigallocatechin-3-O-gallate inhibits fibroblast contraction of floating collagen gel: interaction between epigallocatechin-3-O-gallate and platelet derived growth factor.
Topics: Catechin; Cells, Cultured; Collagen; Fibroblasts; Gels; Humans; Platelet-Derived Growth Factor | 2004 |
Inhibitory effects of green tea polyphenol (-)-epigallocatechin gallate on the expression of matrix metalloproteinase-9 and on the formation of osteoclasts.
Topics: Analysis of Variance; Animals; Animals, Newborn; Bone Marrow Cells; Catechin; Coculture Techniques; Culture Media, Conditioned; Gene Expression; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred ICR; Osteoblasts; Osteoclasts; Plant Extracts; Porphyromonas gingivalis; Protease Inhibitors; RNA, Messenger; Statistics, Nonparametric; Tea | 2004 |
Effect of EGCG, a major component of green tea, on the expression of Ets-1, c-Fos, and c-Jun during angiogenesis in vitro.
Topics: Animals; Anticarcinogenic Agents; Aorta; Blotting, Western; Catechin; Cell Culture Techniques; Cell Division; Collagen; Culture Media; Down-Regulation; Endothelial Cells; Morphogenesis; Neovascularization, Pathologic; Proto-Oncogene Protein c-ets-1; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Transcription Factors; Umbilical Veins | 2004 |
Protective effect of green tea polyphenol EGCG against neuronal damage and brain edema after unilateral cerebral ischemia in gerbils.
Topics: Animals; Brain Edema; Brain Ischemia; Catechin; Cells, Cultured; Flavonoids; Gerbillinae; Hippocampus; Male; Neurons; Neuroprotective Agents; Phenols; Polyphenols; Rats; Rats, Sprague-Dawley; Tea | 2004 |
Anticancer effects of (-)-epigallocatechin-3-gallate on ovarian carcinoma cell lines.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Catechin; Cdc20 Proteins; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cyclin A; Cyclin B; Cyclin B1; Dose-Response Relationship, Drug; Female; Humans; Ovarian Neoplasms; RNA, Messenger | 2004 |
[Epigallocatechin-3-gallate interferes with EBV-encoding AP-1 signal transduction pathway].
Topics: Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Cell Survival; Herpesvirus 4, Human; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Nasopharyngeal Neoplasms; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-jun; Signal Transduction; Transcription Factor AP-1; Viral Matrix Proteins | 2004 |
Triterpenoid saponin from Viola hondoensis W. Becker et H Boss. and their effect on MMP-1 and type I procollagen expression.
Topics: Blotting, Western; Catechin; Cell Proliferation; Cells, Cultured; Collagen Type I; Fibroblasts; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Matrix Metalloproteinase 1; Plant Extracts; Saponins; Triterpenes; Ultraviolet Rays; Viola | 2004 |
Gene expression changes induced by green tea polyphenol (-)-epigallocatechin-3-gallate in human bronchial epithelial 21BES cells analyzed by DNA microarray.
Topics: AlkB Homolog 1, Histone H2a Dioxygenase; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Bronchi; Catalase; Catechin; Cell Line, Transformed; DNA Repair Enzymes; Epithelial Cells; Escherichia coli Proteins; Flavonoids; Gene Expression; Gene Expression Profiling; Genes, ras; Homeodomain Proteins; Humans; Hydrogen Peroxide; Mixed Function Oxygenases; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Peptidylprolyl Isomerase; Phenols; Polycomb Repressive Complex 2; Polyphenols; Tea; Transcription Factors | 2004 |
Local delivery of green tea catechins inhibits neointimal formation in the rat carotid artery injury model.
Topics: Angiography; Angioplasty; Animals; Carotid Arteries; Carotid Artery Injuries; Catechin; Cell Proliferation; Coronary Restenosis; Enzymes; Male; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Rats; Rats, Inbred F344; Recombinant Proteins; Tea; Tunica Intima | 2004 |
Elevated polyamines lead to selective induction of apoptosis and inhibition of tumorigenesis by (-)-epigallocatechin-3-gallate (EGCG) in ODC/Ras transgenic mice.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Biogenic Polyamines; Catechin; Cell Proliferation; Cells, Cultured; Genes, ras; Immunoblotting; Immunohistochemistry; Keratinocytes; Mice; Mice, Transgenic; Ornithine Decarboxylase; ras Proteins; Skin Neoplasms | 2005 |
Prostate carcinoma and green tea: (-)epigallocatechin-3-gallate inhibits inflammation-triggered MMP-2 activation and invasion in murine TRAMP model.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inflammation; Male; Matrix Metalloproteinase 2; Mice; Neoplasm Invasiveness; Prostatic Neoplasms; Tea | 2004 |
Prostate carcinoma and green tea: PSA-triggered basement membrane degradation and MMP-2 activation are inhibited by (-)epigallocatechin-3-gallate.
Topics: Antioxidants; Basement Membrane; Carcinoma; Catechin; Gene Expression Regulation, Neoplastic; Humans; Male; Matrix Metalloproteinase 2; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Factors; Tea; Tumor Cells, Cultured | 2004 |
Prooxidative activities of tea catechins in the presence of Cu2+.
Topics: Antioxidants; Catechin; Copper; Hydrogen Peroxide; Iron; Oxidation-Reduction; Tea | 2004 |
The dietary flavonoids apigenin and (-)-epigallocatechin gallate enhance the positive modulation by diazepam of the activation by GABA of recombinant GABA(A) receptors.
Topics: Animals; Apigenin; Catechin; Diazepam; Diet; Drug Interactions; Flavonoids; gamma-Aminobutyric Acid; Genistein; Humans; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis | 2004 |
Is green tea better than black tea in reducing atherosclerosis?
Topics: Antioxidants; Arteriosclerosis; Camellia sinensis; Catechin; Fermentation; Food Handling; Humans; Inflammation; Phytotherapy; Tea | 2004 |
Green tea constituent epigallocatechin-3-gallate selectively inhibits COX-2 without affecting COX-1 expression in human prostate carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Arachidonic Acid; Catechin; Cell Division; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Humans; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tea; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 2005 |
Chemoprevention of colorectal cancer by grape seed proanthocyanidin is accompanied by a decrease in proliferation and increase in apoptosis.
Topics: Animals; Antioxidants; Apoptosis; Azoxymethane; Biflavonoids; Carcinogens; Caspase 3; Caspases; Catechin; Cell Division; Colorectal Neoplasms; Immunohistochemistry; Male; Proanthocyanidins; Random Allocation; Rats; Rats, Inbred F344 | 2004 |
Tamoxifen and epigallocatechin gallate are synergistically cytotoxic to MDA-MB-231 human breast cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Synergism; Humans; Tamoxifen | 2004 |
A potential prodrug for a green tea polyphenol proteasome inhibitor: evaluation of the peracetate ester of (-)-epigallocatechin gallate [(-)-EGCG].
Topics: Catechin; Drug Evaluation, Preclinical; Esters; Flavonoids; Humans; Jurkat Cells; Peracetic Acid; Phenols; Polyphenols; Prodrugs; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Tea | 2004 |
(-)-Epigallocatechin gallate inhibits lipopolysaccharide-induced microglial activation and protects against inflammation-mediated dopaminergic neuronal injury.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Blotting, Western; Carbocyanines; Catechin; Cell Count; Cells, Cultured; Culture Media, Conditioned; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Lipopolysaccharides; Microglia; Microtubule-Associated Proteins; Neuroblastoma; Neurons; Nitric Oxide; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase | 2004 |
Reversal of cancer multidrug resistance by green tea polyphenols.
Topics: Adenosine Triphosphatases; Animals; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Catechin; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Escherichia coli; Flavonoids; Gene Expression Regulation; Genes, MDR; Genetic Therapy; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Phenols; Polyphenols; Tea; Transformation, Bacterial; Transplantation, Heterologous | 2004 |
Phytoestrogens in common herbs regulate prostate cancer cell growth in vitro.
Topics: Antineoplastic Agents, Hormonal; Catechin; Cell Cycle; Cell Division; Curcumin; DNA Fragmentation; Humans; Male; Phytoestrogens; Prostatic Neoplasms; Quercetin; Receptors, Estrogen; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2004 |
Gene expression spectra in human leukemia HL-60 cells treated with EGCG.
Topics: Base Sequence; Catechin; DNA Primers; Gene Expression Profiling; HL-60 Cells; Humans; Leukemia; Reverse Transcriptase Polymerase Chain Reaction | 2004 |
Green tea epigallocatechin-3-gallate mediates T cellular NF-kappa B inhibition and exerts neuroprotection in autoimmune encephalomyelitis.
Topics: Administration, Oral; Animals; Catechin; Cell Death; Cell Line; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Down-Regulation; Encephalomyelitis, Autoimmune, Experimental; Female; Growth Inhibitors; Humans; I-kappa B Proteins; Immunity, Cellular; Jurkat Cells; Mice; Neurons; Neuroprotective Agents; NF-kappa B; NF-KappaB Inhibitor alpha; Proto-Oncogene Proteins; Reactive Oxygen Species; T-Lymphocytes; Tea; Up-Regulation | 2004 |
In vitro cytotoxicity of epigallocatechin gallate and tea extracts to cancerous and normal cells from the human oral cavity.
Topics: Anticarcinogenic Agents; Camellia sinensis; Carcinoma, Squamous Cell; Catechin; Humans; Lipid Peroxidation; Mouth; Oxidative Stress; Plant Extracts; Tea; Tongue Neoplasms; Tumor Cells, Cultured | 2004 |
Chromosome analysis of mouse zygotes after injecting oocytes with spermatozoa treated in vitro with green tea catechin, (-)-epigallocatechin gallate (EGCG).
Topics: Animals; Catechin; Chromatin; Chromosome Aberrations; Cytogenetic Analysis; Dose-Response Relationship, Drug; Female; Male; Mice; Oocytes; Sperm Injections, Intracytoplasmic; Spermatozoa; Zygote | 2004 |
Green tea polyphenols: antioxidative and prooxidative effects.
Topics: Animals; Antioxidants; Catechin; Drug Stability; Flavonoids; Humans; Neoplasms; Oxidants; Phenols; Polyphenols; Tea; Tumor Cells, Cultured | 2004 |
Effect of epigallocatechin gallate on renal function in cyclosporine-induced nephrotoxicity.
Topics: Antioxidants; Blood Urea Nitrogen; Catechin; Creatinine; Cyclosporine; Humans; Kidney; Kidney Function Tests; Kidney Transplantation | 2004 |
Effect of flavonoids on stress responses in myotube cultures.
Topics: Animals; Catechin; Cell Line; Cell Size; Flavonoids; Hypotonic Solutions; Leukotrienes; Mice; Muscle Fibers, Skeletal; Oxidation-Reduction; Potassium Chloride; Reactive Oxygen Species; Stress, Physiological; Taurine; Tea | 2004 |
Green tea polyphenol-induced epidermal keratinocyte differentiation is associated with coordinated expression of p57/KIP2 and caspase 14.
Topics: Caspase 14; Caspases; Catechin; Cell Differentiation; Cell Line; Cyclin-Dependent Kinase Inhibitor p57; Epidermal Cells; Epidermis; Gene Expression Regulation; Humans; Keratinocytes; Nuclear Proteins; RNA, Messenger; Tea; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Induction of apoptosis by epigallocatechin-3-gallate via mitochondrial signal transduction pathway.
Topics: Anticarcinogenic Agents; Apoptosis; Blotting, Western; Caspase 9; Caspases; Catechin; Cell Line, Tumor; Cell Survival; Humans; Mitochondria; Nasopharyngeal Neoplasms; Signal Transduction | 2004 |
Investigation of intestinal absorption and disposition of green tea catechins by Caco-2 monolayer model.
Topics: Biological Transport; Caco-2 Cells; Catechin; Chromatography, High Pressure Liquid; Humans; Intestinal Absorption; Mass Spectrometry; Tea | 2004 |
Effects of green tea on gene expression of hepatic gluconeogenic enzymes in vivo.
Topics: Animals; Catechin; Diabetes Mellitus; DNA Primers; Dose-Response Relationship, Drug; Gene Expression; Gluconeogenesis; Glucose-6-Phosphatase; Hypoglycemic Agents; Liver; Male; Mice; Mice, Inbred C57BL; Phytotherapy; Plant Extracts; Protein Serine-Threonine Kinases; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tea | 2004 |
Ellipsometry analysis of the in vitro adsorption of tea polyphenols onto salivary pellicles.
Topics: Adsorption; Adult; Antioxidants; Biflavonoids; Buffers; Catechin; Dental Pellicle; Detergents; Durapatite; Flavonoids; Humans; Male; Phenols; Polyphenols; Refractometry; Salivary Proteins and Peptides; Sodium Dodecyl Sulfate; Tannins; Tea; Urokinase-Type Plasminogen Activator | 2004 |
Green tea extract improves endurance capacity and increases muscle lipid oxidation in mice.
Topics: Adipose Tissue; Animals; Catechin; Dose-Response Relationship, Drug; Energy Metabolism; Fatty Acids; Fatty Acids, Nonesterified; Lactic Acid; Lipid Metabolism; Male; Metabolism; Mice; Mice, Inbred BALB C; Muscle, Skeletal; Organ Size; Oxidation-Reduction; Physical Endurance; Plant Extracts; RNA, Messenger; Swimming; Tea | 2005 |
Neuroprotective effects of (-)-epigallocatechin gallate following hypoxia-ischemia-induced brain damage: novel mechanisms of action.
Topics: Aconitate Hydratase; Animals; Arginase; Brain; Catechin; Citrate (si)-Synthase; Electron Transport Complex I; Electron Transport Complex II; Electron Transport Complex III; Electron Transport Complex IV; Hypoxia-Ischemia, Brain; Male; Mitochondrial Proton-Translocating ATPases; Nerve Tissue Proteins; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Rats; Rats, Wistar; Reactive Oxygen Species | 2005 |
New apoptosis cascade mediated by lysosomal enzyme and its protection by epigallo-catechin gallate.
Topics: Amino Acid Substitution; Animals; Apoptosis; Caspase 3; Caspases; Catechin; Cell Death; Galactosamine; Kinetics; Lactoferrin; Liver; Lysosomes; Models, Biological; Protease Inhibitors; Protein Processing, Post-Translational; Recombinant Proteins | 2004 |
Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor.
Topics: Adenosine Triphosphate; Bacterial Proteins; Biosensing Techniques; Calcium; Calmodulin; Catechin; Cell Line, Tumor; Endoplasmic Reticulum; Fluorescence; Gene Expression Regulation, Neoplastic; Genetic Engineering; Humans; Luminescent Proteins; Molecular Sequence Data; Mutation; Proto-Oncogene Proteins c-bcl-2; Tea | 2004 |
More benefits for green tea drinkers?
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Catechin; Contraindications; Humans; Tea | 2004 |
Effects of (-)-epigallocatechin-3-gallate on expression of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 in fibroblasts irradiated with ultraviolet A.
Topics: Catechin; Cells, Cultured; Fibroblasts; Gene Expression Regulation; Humans; Matrix Metalloproteinase 1; Proto-Oncogene Proteins c-jun; Radiation-Protective Agents; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Ultraviolet Rays | 2004 |
Anti-proliferative and proapoptotic effects of (-)-epigallocatechin-3-gallate on human melanoma: possible implications for the chemoprevention of melanoma.
Topics: Agar; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 7; Caspase 9; Caspases; Catechin; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Separation; Cell Survival; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Down-Regulation; Flow Cytometry; Humans; Immunoblotting; Immunohistochemistry; In Situ Nick-End Labeling; Ki-67 Antigen; Melanocytes; Melanoma; Membrane Potentials; Mitochondria; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Time Factors | 2005 |
Protective mechanism of epigallocatechin-3-gallate against Helicobacter pylori-induced gastric epithelial cytotoxicity via the blockage of TLR-4 signaling.
Topics: Apoptosis; Catechin; Cells, Cultured; Enzyme Inhibitors; Gastric Mucosa; Glycosylation; Helicobacter pylori; Humans; MAP Kinase Kinase 2; Membrane Glycoproteins; Mitogen-Activated Protein Kinase 3; NF-kappa B; Receptors, Cell Surface; Signal Transduction; Toll-Like Receptor 4; Toll-Like Receptors | 2004 |
Transactivation of peroxisome proliferator-activated receptor alpha by green tea extracts.
Topics: Animals; Camellia sinensis; Catechin; Chlorocebus aethiops; COS Cells; Plant Extracts; Plasmids; PPAR alpha; Tea; Transcriptional Activation; Transfection | 2004 |
Complexation of epigallocatechin gallate (a green tea extract, egcg) with Mn2+: nuclear spin relaxation by the paramagnetic ion.
Topics: Binding Sites; Catechin; Magnetic Resonance Spectroscopy; Manganese; Molecular Structure; Plant Extracts; Tea | 2005 |
Toxicity of green tea extracts and their constituents in rat hepatocytes in primary culture.
Topics: Animals; Biological Availability; Catechin; Cells, Cultured; Chemical and Drug Induced Liver Injury; Hepatocytes; Intestinal Absorption; L-Lactate Dehydrogenase; Male; Oxazines; Plant Extracts; Rats; Rats, Wistar; Tea; Xanthenes | 2005 |
Glucuronidation of the green tea catechins, (-)-epigallocatechin-3-gallate and (-)-epicatechin-3-gallate, by rat hepatic and intestinal microsomes.
Topics: Animals; Catechin; Chromatography, High Pressure Liquid; Glucuronides; Ileum; In Vitro Techniques; Jejunum; Liver; Male; Mass Spectrometry; Microsomes; Microsomes, Liver; Quercetin; Rats; Rats, Wistar; Tea; Uridine Diphosphate Glucuronic Acid | 2004 |
Protective effects of green tea catechins on alveolar macrophages against bacterial infections.
Topics: Bacterial Infections; Catechin; Cell Line; Humans; Macrophages, Alveolar; Phytotherapy; Tea | 2004 |
A difference between epigallocatechin-3-gallate and epicatechin-3-gallate on anti-allergic effect is dependent on their distinct distribution to lipid rafts.
Topics: Basophils; Catechin; Cell Line; Histamine H1 Antagonists; Humans; Membrane Microdomains | 2004 |
Tea polyphenol epigallocatechin-3-gallate associates with plasma membrane lipid rafts: lipid rafts mediate anti-allergic action of the catechin.
Topics: Antioxidants; Basophils; Catechin; Cell Line, Tumor; Cell Membrane; Histamine H1 Antagonists; Humans; Membrane Microdomains; Receptors, IgE; Tea | 2004 |
Tea catechin, epigallocatechin-3-gallate suppresses myosin II regulatory light chain phosphorylation.
Topics: Antioxidants; Catechin; HeLa Cells; Humans; Myosin Light Chains; Phosphorylation; Stress, Mechanical; Tea | 2004 |
Cytotoxicity of epigallocatechin-3-gallate to LNCaP cells in the presence of Cu2+.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Copper; Dose-Response Relationship, Drug; Drug Combinations; Humans; Male; Prostatic Neoplasms | 2005 |
Green tea's benefits finding their way into everyday products. Chewing gum may alleviate dry mouth condition.
Topics: Anticarcinogenic Agents; Antioxidants; Camellia sinensis; Catechin; Chewing Gum; Humans; Phytotherapy; Plant Leaves; Salivation; Tea | 2004 |
The green tea polyphenol (-)-epigallocatechin gallate and green tea can protect human cellular DNA from ultraviolet and visible radiation-induced damage.
Topics: Antimutagenic Agents; Antioxidants; Catechin; Cells, Cultured; Comet Assay; DNA Damage; Fibroblasts; Flavonoids; Humans; Molecular Structure; Phenols; Polyphenols; Radiation-Protective Agents; Skin Neoplasms; Statistics, Nonparametric; Tea; Ultraviolet Rays | 2005 |
Epigallocatechin gallate induces apoptosis of monocytes.
Topics: Anti-Inflammatory Agents; Apoptosis; Caspases; Catechin; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Monocytes; Tea | 2005 |
Antitumor effect of nutrient synergy on human osteosarcoma cells U-2OS, MNNG-HOS and Ewing's sarcoma SK-ES.1.
Topics: Arginine; Ascorbic Acid; Bone Neoplasms; Catechin; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Lysine; Matrix Metalloproteinases; Neovascularization, Pathologic; Nutritional Physiological Phenomena; Osteosarcoma; Proline; Sarcoma, Ewing; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2005 |
Catechin gallates inhibit multidrug resistance (MDR) in Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Catechin; Drug Resistance, Multiple; Humans; Microbial Sensitivity Tests; Phytotherapy; Plants, Medicinal; Staphylococcus aureus | 2004 |
Antimitogenic effect of green tea (-)-epigallocatechin gallate on 3T3-L1 preadipocytes depends on the ERK and Cdk2 pathways.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Catechin; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p18; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Extracellular Signal-Regulated MAP Kinases; Genes, jun; Mice; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Tea; Tumor Suppressor Proteins | 2005 |
Increased radiation sensitivity of an eosinophilic cell line following treatment with epigallocatechin-gallate, resveratrol and curcuma.
Topics: Annexin A5; Apoptosis; Catechin; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Curcuma; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Eosinophils; Flow Cytometry; Humans; Leukemia; Necrosis; Plant Extracts; Radiation Tolerance; Radiation, Ionizing; Resveratrol; Signal Transduction; Stilbenes; Time Factors; X-Rays | 2005 |
Differential in vitro cytotoxicity of (-)-epicatechin gallate (ECG) to cancer and normal cells from the human oral cavity.
Topics: Antioxidants; Apoptosis; Carcinoma, Squamous Cell; Catechin; Cell Survival; DNA; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fibroblasts; Gingiva; Humans; Mouth Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured | 2005 |
Iron and alpha-synuclein in the substantia nigra of MPTP-treated mice: effect of neuroprotective drugs R-apomorphine and green tea polyphenol (-)-epigallocatechin-3-gallate.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Animals; Apomorphine; Catechin; Disease Models, Animal; Free Radicals; Iron; Iron Chelating Agents; Lewy Bodies; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Substantia Nigra; Synucleins; Ubiquitin | 2004 |
Epigallocatechin-3-gallate induces apoptosis in estrogen receptor-negative human breast carcinoma cells via modulation in protein expression of p53 and Bax and caspase-3 activation.
Topics: Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Catechin; Cell Line, Tumor; Enzyme Activation; Female; Humans; Proto-Oncogene Proteins c-bcl-2; Receptors, Estrogen; Tumor Suppressor Protein p53 | 2005 |
Tea catechins with a galloyl moiety suppress postprandial hypertriacylglycerolemia by delaying lymphatic transport of dietary fat in rats.
Topics: Animals; Antioxidants; Biological Transport; Catechin; Dietary Fats; Hypertriglyceridemia; Lymphatic System; Male; Models, Animal; Rats; Rats, Wistar; Tea | 2005 |
Epigallocatechin gallate induces telomere fragmentation in HeLa and 293 but not in MRC-5 cells.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Free Radical Scavengers; HeLa Cells; Humans; Reactive Oxygen Species; Telomere | 2005 |
Cellular basis of the role of diesel exhaust particles in inducing Th2-dominant response.
Topics: Acetylcysteine; Adult; Air Pollutants; Antioxidants; Catechin; Cells, Cultured; Cytokines; Dendritic Cells; Female; Humans; Immunosuppressive Agents; Inflammation Mediators; Interferon-gamma; Interleukin-10; Lymphocyte Activation; Male; Monocytes; Oxidative Stress; RNA, Messenger; Th2 Cells; Vehicle Emissions | 2005 |
Epigallocatechin-3-gallate induces mitochondrial membrane depolarization and caspase-dependent apoptosis in pancreatic cancer cells.
Topics: Antioxidants; Apoptosis; Caspases; Catechin; Cell Proliferation; Cytochromes c; Cytosol; G2 Phase; Humans; JNK Mitogen-Activated Protein Kinases; Membrane Potentials; Mitochondria; Pancreatic Neoplasms; Signal Transduction; Tea | 2005 |
tNOX is both necessary and sufficient as a cellular target for the anticancer actions of capsaicin and the green tea catechin (-)-epigallocatechin-3-gallate.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Breast; Capsaicin; Catechin; Cell Division; Cell Line; Chlorocebus aethiops; COS Cells; HeLa Cells; Humans; Kidney; Kinetics; NADH, NADPH Oxidoreductases; Polymerase Chain Reaction; Tea; Transfection | 2004 |
Epigallocatechin-3-gallate causes the p21/WAF1-mediated G(1)-phase arrest of cell cycle and inhibits matrix metalloproteinase-9 expression in TNF-alpha-induced vascular smooth muscle cells.
Topics: Arteriosclerosis; Catechin; Cell Cycle; Cell Cycle Proteins; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; G1 Phase; Gene Expression Regulation; Humans; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Muscle, Smooth, Vascular; NF-kappa B; Promoter Regions, Genetic; Protease Inhibitors; Transcription Factor AP-1; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2005 |
Comment on inhibitory effect of (-)-epigallocatechin 3-gallate, a polyphenol of green tea, on neutrophil chemotaxis in vitro and in vivo.
Topics: Catechin; Chemotaxis, Leukocyte; Neutrophils; Tea | 2005 |
The intermediate filament protein vimentin is a new target for epigallocatechin gallate.
Topics: Amino Acid Sequence; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Blotting, Western; Catechin; Cell Line; Cell Proliferation; Chromatography, Affinity; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Flavonoids; Genetic Vectors; Glutathione Transferase; Humans; Immunoprecipitation; Inhibitory Concentration 50; Kinetics; Mice; Microscopy, Fluorescence; Models, Chemical; Molecular Sequence Data; Peptides; Phenols; Phosphorylation; Polyphenols; Protein Binding; Protein Structure, Tertiary; RNA, Small Interfering; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors; Vimentin | 2005 |
Human epidermal keratinocytes undergo (-)-epigallocatechin-3-gallate-dependent differentiation but not apoptosis.
Topics: Apoptosis; Calcium; Caspases; Catechin; Cell Differentiation; Cells, Cultured; Cytochromes c; Enzyme Activation; Epidermal Cells; Epidermis; Humans; Keratinocytes; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Transglutaminases | 2005 |
Short-term administration of (-)-epigallocatechin gallate reduces hepatic steatosis and protects against warm hepatic ischemia/reperfusion injury in steatotic mice.
Topics: Animals; Antioxidants; Body Weight; Catechin; Disease Models, Animal; Energy Intake; Energy Metabolism; Fatty Liver; Hepatocytes; Liver; Liver Circulation; Male; Mice; Mice, Obese; Necrosis; Reperfusion Injury | 2005 |
Protective effects of (-)-epicatechin-3-gallate on UVA-induced damage in HaCaT keratinocytes.
Topics: Antioxidants; Catechin; Cell Death; Cell Line; Humans; Hydrogen Peroxide; Keratinocytes; Ultraviolet Rays; Xanthine Oxidase | 2005 |
[Preparation and component analysis of tea pigments].
Topics: Biflavonoids; Caffeine; Catechin; Chromatography, High Pressure Liquid; Gallic Acid; Phenols; Pigments, Biological; Polyphenols; Tea | 2004 |
Green tea extract and (-)-epigallocatechin-3-gallate, the major tea catechin, exert oxidant but lack antioxidant activities.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Camellia sinensis; Catechin; Cell Line; Comet Assay; DNA Damage; HL-60 Cells; Humans; Hydrogen Peroxide; Macrophages; Mice; Oxidants; Oxidative Stress; Plant Extracts | 2005 |
Epigallocatechin gallate attenuates diet-induced obesity in mice by decreasing energy absorption and increasing fat oxidation.
Topics: Animals; Antioxidants; Body Composition; Body Temperature; Calorimetry, Indirect; Carrier Proteins; Catechin; Dietary Supplements; Eating; Glucokinase; Intestinal Absorption; Ion Channels; Leptin; Lipid Metabolism; Malate Dehydrogenase; Male; Membrane Proteins; Membrane Transport Proteins; Mice; Mice, Inbred NZB; Mitochondrial Proteins; Obesity; Oxidation-Reduction; Pyruvate Kinase; Stearoyl-CoA Desaturase; Tissue Distribution; Uncoupling Protein 1; Uncoupling Protein 2; Uncoupling Protein 3 | 2005 |
Platelet aggregation induced by the C-terminal peptide of thrombospondin-1 (4N1-1) is inhibited by epigallocatechin gallate but not by prostaglandin E1.
Topics: Alprostadil; Catechin; Cells, Cultured; Humans; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Protease Inhibitors; Thrombospondin 1 | 2004 |
Evaluation of proteasome-inhibitory and apoptosis-inducing potencies of novel (-)-EGCG analogs and their prodrugs.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Flavonoids; Humans; Jurkat Cells; Phenols; Polyphenols; Prodrugs; Proteasome Inhibitors; Tea | 2005 |
Epigallocatechin-3-gallate from green tea negatively affects swine granulosa cell function.
Topics: Animals; Anti-Infective Agents; Camellia sinensis; Catechin; Cell Division; Estradiol; Female; Granulosa Cells; Hydrogen Peroxide; Progesterone; Superoxide Dismutase; Superoxides; Swine; Tea; Vascular Endothelial Growth Factor A | 2005 |
The effect of tiarellic acid on the expressions of matrix metalloproteinase-1 and type 1 procollagen in ultraviolet irradiated cultured human skin fibroblasts.
Topics: Catechin; Cells, Cultured; Collagen Type I; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression; Humans; Matrix Metalloproteinase 1; Matrix Metalloproteinase Inhibitors; Plants, Medicinal; Skin; Time Factors; Triterpenes; Ultraviolet Rays | 2005 |
Reaction pH and protein affect the oxidation products of beta-pentagalloyl glucose.
Topics: Biflavonoids; Catechin; Free Radicals; Hydrogen-Ion Concentration; Hydrolyzable Tannins; Molecular Conformation; Oxidation-Reduction; Periodic Acid; Proanthocyanidins; Quinones; Serum Albumin, Bovine; Zinc | 2005 |
Ablation of either p21 or Bax prevents p53-dependent apoptosis induced by green tea polyphenol epigallocatechin-3-gallate.
Topics: Apoptosis; bcl-2-Associated X Protein; Camellia sinensis; Catechin; Cell Division; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; G1 Phase; Humans; Male; Prostatic Neoplasms; RNA, Small Interfering; Transfection; Tumor Suppressor Protein p53 | 2005 |
Synthetic peracetate tea polyphenols as potent proteasome inhibitors and apoptosis inducers in human cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Flavonoids; Humans; Hydrogen Peroxide; Jurkat Cells; Phenols; Polyphenols; Proteasome Inhibitors; Tea; Tumor Cells, Cultured | 2005 |
The antifolate activity of tea catechins.
Topics: Animals; Catechin; Cattle; Chickens; Enzyme Inhibitors; Folic Acid Antagonists; Humans; Kinetics; Leukemia L1210; Liver; Mice; Models, Molecular; Quinazolines; Tea; Tetrahydrofolate Dehydrogenase | 2005 |
Protective effect of epigallocatechin gallate and esculetin on oxidative DNA damage induced by psoralen plus ultraviolet-A therapy.
Topics: Catechin; DNA Damage; Ficusin; Oxidative Stress; PUVA Therapy; Umbelliferones | 2005 |
Epigallocatechin gallate inhibits aryl hydrocarbon receptor gene transcription through an indirect mechanism involving binding to a 90 kDa heat shock protein.
Topics: Animals; Binding Sites; Catechin; Cell Line, Tumor; Chickens; HSP90 Heat-Shock Proteins; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Ligands; Mice; Models, Biological; Multiprotein Complexes; Polychlorinated Dibenzodioxins; Protein Binding; Proteins; Receptors, Aryl Hydrocarbon; Recombinant Proteins; Transcription, Genetic | 2005 |
Repressions of MMP-9 expression and NF-kappa B localization are involved in inhibition of lung carcinoma 95-D cell invasion by (-)-epigallocatechin-3-gallate.
Topics: Antioxidants; Blotting, Western; Catechin; Down-Regulation; Humans; Lung Neoplasms; Matrix Metalloproteinase Inhibitors; Neoplasm Metastasis; NF-kappa B; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2005 |
(-)Epigallocatechin gallate and quercetin enhance survival signaling in response to oxidant-induced human endothelial apoptosis.
Topics: Apoptosis; Catechin; Cell Line; Cell Survival; Endothelium, Vascular; Glutathione; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Oxidants; Phosphorylation; Quercetin; Reactive Oxygen Species; Umbilical Veins | 2005 |
Contribution of flavonoid antioxidants to the preventive effect of mesna in cyclophosphamide-induced cystitis in rats.
Topics: Animals; Antineoplastic Agents, Alkylating; Antioxidants; Catechin; Cyclophosphamide; Cystitis; Drug Therapy, Combination; Flavonoids; Hematuria; Injections, Intraperitoneal; Male; Malondialdehyde; Mesna; Organ Size; Protective Agents; Quercetin; Rats; Rats, Sprague-Dawley; Urinary Bladder | 2005 |
Effects of tea constituents on cell cycle progression of human leukemia U937 cells.
Topics: Anticarcinogenic Agents; Apoptosis; Base Sequence; Camellia sinensis; Catechin; Cell Cycle; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p21; DNA, Neoplasm; Humans; Molecular Weight; Plant Extracts; Tea; U937 Cells; Up-Regulation | 2005 |
Structure-activity relationship of the tocopherol-regeneration reaction by catechins.
Topics: Catechin; Kinetics; Structure-Activity Relationship; Tocopherols | 2005 |
(-)-Epigallocatechin gallate and polyphenon E inhibit growth and activation of the epidermal growth factor receptor and human epidermal growth factor receptor-2 signaling pathways in human colon cancer cells.
Topics: Antioxidants; Apoptosis; Blotting, Western; Caco-2 Cells; Caspase 3; Caspase 9; Caspases; Catechin; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Cyclin D1; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; G1 Phase; Gene Expression Regulation; HT29 Cells; Humans; NF-kappa B; Phosphorylation; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-fos; Receptor, ErbB-2; Signal Transduction; Transcription Factor AP-1 | 2005 |
EGCG, a major component of green tea, inhibits VEGF production by swine granulosa cells.
Topics: Animals; Camellia sinensis; Catechin; Cells, Cultured; Female; Granulosa Cells; Plant Leaves; Swine; Vascular Endothelial Growth Factor A | 2005 |
Correlation of apoptosis with comet formation induced by tea polyphenols in human leukemia cells.
Topics: Antioxidants; Apoptosis; Biflavonoids; Caspase 3; Caspase 8; Caspases; Catechin; Comet Assay; Flavonoids; Flow Cytometry; HL-60 Cells; Humans; K562 Cells; Phenols; Polyphenols; Tea | 2005 |
Amelioration of sodium arsenite-induced clastogenicity by tea extracts in Chinese hamster v79 cells.
Topics: Animals; Antimutagenic Agents; Antioxidants; Arsenites; Biflavonoids; Camellia sinensis; Catalase; Catechin; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; DNA Repair; Fibroblasts; Plant Extracts; Sodium Compounds; Superoxide Dismutase; Tea; Water Pollutants, Chemical | 2005 |
The acid-promoted reaction of the green tea polyphenol epigallocatechin gallate with nitrite ions.
Topics: Catechin; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Nitrites; Tea | 2005 |
Physicochemical characteristics and in vivo deposition of liposome-encapsulated tea catechins by topical and intratumor administrations.
Topics: Administration, Topical; Animals; Catechin; Deoxycholic Acid; Drug Evaluation, Preclinical; Drug Stability; Injections, Intralesional; Liposomes; Mice; Mice, Nude; Neoplasms, Experimental; Organophosphates; Skin; Skin Neoplasms; Tea | 2005 |
Pathophysiological response of rhesus monkey kidney epithelial cells exposed to epigallocatechin-3-gallate.
Topics: Animals; Antioxidants; Camellia sinensis; Catechin; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Epithelial Cells; Kidney; Macaca mulatta; Plant Extracts; Plant Leaves | 2005 |
Inhibition of human liver catechol-O-methyltransferase by tea catechins and their metabolites: structure-activity relationship and molecular-modeling studies.
Topics: Catechin; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Humans; Liver; Models, Molecular; Structure-Activity Relationship; Tea | 2005 |
(-)-Epigallocatechin-3-gallate promotes pro-matrix metalloproteinase-7 production via activation of the JNK1/2 pathway in HT-29 human colorectal cancer cells.
Topics: Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Colorectal Neoplasms; Enzyme Activation; Enzyme Precursors; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 7; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; p38 Mitogen-Activated Protein Kinases | 2005 |
Catechins prevent vascular smooth muscle cell invasion by inhibiting MT1-MMP activity and MMP-2 expression.
Topics: Aorta; Atherosclerosis; Blotting, Northern; Blotting, Western; Catechin; Cell Movement; Cells, Cultured; Gene Expression; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Muscle, Smooth, Vascular; Neoplasms; Tea; Thrombin | 2005 |
Model of inhibition of Thermus aquaticus polymerase and Moloney murine leukemia virus reverse transcriptase by tea polyphenols (+)-catechin and (-)-epigallocatechin-3-gallate.
Topics: Animals; Anticarcinogenic Agents; Catechin; Flavonoids; Mice; Moloney murine leukemia virus; Phenols; Phytotherapy; Polyphenols; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA-Directed DNA Polymerase; Taq Polymerase; Tea | 2005 |
Kinetics of the inhibition of bovine liver dihydrofolate reductase by tea catechins: origin of slow-binding inhibition and pH studies.
Topics: Amino Acid Sequence; Animals; Binding Sites; Camellia sinensis; Catechin; Cattle; Flavonoids; Folic Acid Antagonists; Humans; Hydrogen-Ion Concentration; Kinetics; Liver; Models, Chemical; Molecular Sequence Data; Phenols; Polyphenols; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tea; Tetrahydrofolate Dehydrogenase | 2005 |
Black tea polyphenols suppress cell proliferation and induce apoptosis during benzo(a)pyrene-induced lung carcinogenesis.
Topics: Animals; Apoptosis; Benzo(a)pyrene; Biflavonoids; Carcinoma in Situ; Catechin; Cell Proliferation; Lung Neoplasms; Mice; Tea | 2005 |
Modulation of neuronal activity by EGCG.
Topics: Action Potentials; Animals; Catechin; Neurons; Neuroprotective Agents; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Vestibular Nuclei | 2005 |
Inhibitory effect of the tea polyphenol, (-)-epigallocatechin gallate, on growth of cervical adenocarcinoma cell lines.
Topics: Adenocarcinoma; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Female; Flavonoids; Flow Cytometry; Humans; Ki-67 Antigen; Phenols; Polyphenols; Tea; Telomerase; Uterine Cervical Neoplasms | 2006 |
Reversal of multidrug resistance in KB cells with tea polyphenol antioxidant capacity.
Topics: Antioxidants; Catechin; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Flavonoids; Humans; KB Cells; Oxidative Stress; Phenols; Polyphenols; Reactive Oxygen Species; Tea | 2005 |
Biosynthesized tea polyphenols inactivate Chlamydia trachomatis in vitro.
Topics: Anti-Bacterial Agents; Catechin; Chlamydia trachomatis; Flavonoids; HeLa Cells; Humans; Microbial Sensitivity Tests; Phenols; Polyphenols; Tea | 2005 |
Pharmacologic manipulation of the ataxia-telangiectasia mutated gene product as an intervention in age-related disease.
Topics: Aging; Animals; Antioxidants; Ataxia Telangiectasia Mutated Proteins; Catechin; Cell Cycle Proteins; DNA-Binding Proteins; Enzyme Inhibitors; Genistein; Humans; Insulin-Like Growth Factor I; Mice; Models, Biological; Models, Theoretical; Mutation; Oxidants; Protein Serine-Threonine Kinases; Quercetin; Signal Transduction; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2005 |
Growth of LNCaP cells in monoculture and coculture with osteoblasts and response to tNOX inhibitors.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Bone Neoplasms; Capsaicin; Catechin; Cell Survival; Cisplatin; Humans; Isoflavones; Male; Osteoblasts; Paclitaxel; Plant Extracts; Prostatic Neoplasms; Tumor Cells, Cultured | 2005 |
(-)-Epigallocatechin gallate as an intervention for the acute treatment of cerebral ischemia.
Topics: Alanine Transaminase; Animals; Brain; Brain Ischemia; Catechin; Infarction, Middle Cerebral Artery; Liver; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2005 |
Green tea polyphenol (-)-epigallocatechin-3-gallate induces neurorescue of long-term serum-deprived PC12 cells and promotes neurite outgrowth.
Topics: Animals; Biological Transport; Catechin; Cell Death; Cell Differentiation; Cell Membrane; Culture Media, Serum-Free; Enzyme Activation; Flavonoids; Neurites; Neuroprotective Agents; PC12 Cells; Phenols; Polyphenols; Protein Kinase C; Protein Kinase C-alpha; Rats | 2005 |
Novel inhibitors of fatty-acid synthase from green tea (Camellia sinensis Xihu Longjing) with high activity and a new reacting site.
Topics: Camellia sinensis; Catechin; Enzyme Inhibitors; Fatty Acid Synthases; Flavonoids; Inhibitory Concentration 50; Obesity; Phenols; Plant Extracts; Polyphenols; Tea | 2006 |
Epigallocatechin-3-O-gallate disrupts stress fibers and the contractile ring by reducing myosin regulatory light chain phosphorylation mediated through the target molecule 67 kDa laminin receptor.
Topics: Actins; Catechin; Cell Proliferation; Contractile Proteins; Dose-Response Relationship, Drug; Gene Expression Regulation; HeLa Cells; Humans; Myosin Light Chains; Phosphorylation; Receptors, Laminin; Stress Fibers | 2005 |
Green tea polyphenol epigallocatechin-3-gallate blocks PDGF-induced proliferation and migration of rat pancreatic stellate cells.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Division; Cell Movement; Drug Interactions; Flavonoids; Hepatocytes; Male; Phenols; Platelet-Derived Growth Factor; Polyphenols; Rats; Rats, Wistar; Signal Transduction; Tea | 2005 |
[Effect of epigallocatechingallate on acute lung injury induced by oleic acid in mice].
Topics: Animals; Catechin; Lung; Male; Mice; Oleic Acid; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protective Agents; Respiratory Distress Syndrome; Tumor Necrosis Factor-alpha | 2005 |
Effects of epigallocatechin gallate on the hemolysis induced by cyclosporine.
Topics: Catechin; Cyclosporine; Erythrocytes; Free Radical Scavengers; Hemolysis; Humans; In Vitro Techniques | 2005 |
Differential inhibition of oxidized LDL-induced apoptosis in human endothelial cells treated with different flavonoids.
Topics: Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Catechin; Cells, Cultured; Copper; Endothelial Cells; Flavonoids; Gene Expression; Genes, bcl-2; Hesperidin; Humans; Lipoproteins, LDL; Proto-Oncogene Proteins c-bcl-2; Quercetin; Rutin; Thiobarbituric Acid Reactive Substances; Umbilical Veins | 2005 |
The tea polyphenols EGCG and EGC repress mRNA expression of human telomerase reverse transcriptase (hTERT) in carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Camellia sinensis; Catechin; Cell Line, Tumor; Cell Survival; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Drug Delivery Systems; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; RNA, Messenger; Telomerase; Time Factors | 2006 |
Green tea polyphenol epigallocatechin gallate inhibits adipogenesis and induces apoptosis in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Apoptosis; Azo Compounds; Catechin; Cell Differentiation; Coloring Agents; In Situ Nick-End Labeling; Laser Scanning Cytometry; Mice; Tea | 2005 |
Epigallocatechin-3-gallate, a green-tea polyphenol, suppresses Rho signaling in TWNT-4 human hepatic stellate cells.
Topics: Actins; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Division; Cell Line; Flavonoids; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Hepatocytes; Humans; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Liver Cirrhosis; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phenols; Phosphorylation; Polyphenols; Protein-Tyrosine Kinases; rho GTP-Binding Proteins; Stress Fibers; Tea | 2005 |
About the cover illustration: Thea sinensis - the common tea plant.
Topics: Anticarcinogenic Agents; Camellia sinensis; Catechin; Humans; Liver Diseases; Phytotherapy | 2005 |
Antifolate activity of epigallocatechin gallate against Stenotrophomonas maltophilia.
Topics: Anti-Bacterial Agents; Catechin; Folic Acid Antagonists; Humans; Kinetics; Methotrexate; Microbial Sensitivity Tests; Stenotrophomonas maltophilia; Tetrahydrofolate Dehydrogenase; Trimethoprim; Trimethoprim Resistance | 2005 |
Probing the infiltrating character of brain tumors: inhibition of RhoA/ROK-mediated CD44 cell surface shedding from glioma cells by the green tea catechin EGCg.
Topics: Brain Neoplasms; Catechin; Cell Adhesion; Cell Line, Tumor; Cell Membrane; Cell Movement; Glioma; Humans; Hyaluronan Receptors; Hyaluronic Acid; Intracellular Signaling Peptides and Proteins; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Neoplasm Invasiveness; Protein Serine-Threonine Kinases; Recombinant Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Transfection | 2005 |
Green tea polyphenol extract attenuates ischemia/reperfusion injury of the gut.
Topics: Animals; Antioxidants; Blood Pressure; Catechin; Flavonoids; Ileum; Intercellular Adhesion Molecule-1; Male; P-Selectin; Phenols; Plant Extracts; Polyphenols; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Splanchnic Circulation; Structure-Activity Relationship; Tea | 2005 |
The apoptotic effect of green tea (-)-epigallocatechin gallate on 3T3-L1 preadipocytes depends on the Cdk2 pathway.
Topics: 3T3 Cells; Adipocytes; Animals; Apoptosis; Camellia sinensis; Caspase 3; Caspases; Catechin; CDC2-CDC28 Kinases; Cyclin-Dependent Kinase 2; DNA Fragmentation; Gene Expression; Mice; Stem Cells; Transfection | 2005 |
Activity of NADPH-cytochrome P-450 reductase of the human heart, liver and lungs in the presence of (-)-epigallocatechin gallate, quercetin and resveratrol: an in vitro study.
Topics: Anti-Bacterial Agents; Antioxidants; Catechin; Diet; Doxorubicin; Enzyme Activation; Heart; Herbicides; Humans; In Vitro Techniques; Liver; Lung; Male; Microsomes, Liver; Myocardium; NADPH-Ferrihemoprotein Reductase; Paraquat; Quercetin; Resveratrol; Stilbenes | 2005 |
Epigallocatechin gallate inhibits HIF-1alpha degradation in prostate cancer cells.
Topics: Catechin; Cell Line, Tumor; DNA-Binding Proteins; Dose-Response Relationship, Drug; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Nuclear Proteins; Prostatic Neoplasms; Transcription Factors; Up-Regulation | 2005 |
Molecular characterization of the gallate dioxygenase from Pseudomonas putida KT2440. The prototype of a new subgroup of extradiol dioxygenases.
Topics: Amino Acid Sequence; Benzidines; Catalase; Catechin; Cloning, Molecular; Coumaric Acids; Dioxygenases; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gallic Acid; Gene Expression Regulation, Bacterial; Hydrogen-Ion Concentration; Indoles; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutation; Oxygenases; Peroxidase; Phylogeny; Plasmids; Protein Structure, Tertiary; Pseudomonas putida; Sequence Homology, Amino Acid; Spectrophotometry; Sphingomonas; Substrate Specificity; Time Factors; Vanillic Acid | 2005 |
Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids.
Topics: Catechin; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Flavonoids; Humans; Kinetics; Promoter Regions, Genetic; Tea | 2005 |
Inhibition of autoantigen expression by (-)-epigallocatechin-3-gallate (the major constituent of green tea) in normal human cells.
Topics: Autoantigens; Blotting, Western; Catechin; Cell Line; Down-Regulation; Humans; Keratinocytes; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA; Salivary Glands | 2005 |
Examination of the anti-oxidative effect in renal tubular cells and apoptosis by oxidative stress.
Topics: Animals; Antioxidants; Apoptosis; Catechin; Cell Line; Dogs; Immunohistochemistry; Kidney Tubules; Osteopontin; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; Sialoglycoproteins; Superoxide Dismutase | 2005 |
Black tea extract can modulate protein expression of H-ras, c-Myc, p53, and Bcl-2 genes during pulmonary hyperplasia, dysplasia, and carcinoma in situ.
Topics: Animals; Animals, Newborn; Anticarcinogenic Agents; Apoptosis; Benzo(a)pyrene; Biflavonoids; Carcinoma in Situ; Catechin; Cell Proliferation; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Hyperplasia; Lung; Lung Neoplasms; Male; Mice; Plant Extracts; Proto-Oncogene Proteins; Proto-Oncogenes; Tea | 2005 |
Mechanisms of the inhibitory effect of epigallocatechin-3-gallate on cultured human vascular smooth muscle cell invasion.
Topics: Antioxidants; Catechin; Cell Adhesion; Cell Movement; Cells, Cultured; Collagen Type I; Collagenases; Enzyme Precursors; Gelatinases; Humans; In Vitro Techniques; Matrix Metalloproteinase 13; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Muscle, Smooth, Vascular; RNA, Messenger; RNA, Small Interfering; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transfection | 2005 |
(-)-Epigallocatechin-3-gallate, a polyphenolic compound from green tea, inhibits fibroblast adhesion and migration through multiple mechanisms.
Topics: Actins; Antibodies; Catechin; Cell Adhesion; Cell Line; Cell Line, Tumor; Cell Movement; Coculture Techniques; Cytoskeleton; Extracellular Matrix; Extracellular Matrix Proteins; Fibroblasts; Humans; Hydrogen Peroxide; Integrin alpha2beta1; Matrix Metalloproteinase Inhibitors; Melanoma; Tea | 2005 |
EGCG inhibits activation of the insulin-like growth factor-1 receptor in human colon cancer cells.
Topics: Catechin; Cell Line, Tumor; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Matrix Metalloproteinase 7; Matrix Metalloproteinase 9; Receptor, IGF Type 1; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta2 | 2005 |
Lysosomal trafficking of beta-catenin induced by the tea polyphenol epigallocatechin-3-gallate.
Topics: Anticarcinogenic Agents; beta Catenin; Cadherins; Catechin; Cell Line; Colonic Neoplasms; Colorectal Neoplasms; Genes, Reporter; Humans; Lysosomes; Recombinant Fusion Proteins; Signal Transduction; TCF Transcription Factors; Tea; Transcription Factor 7-Like 2 Protein | 2005 |
One-step purification of epigallocatechin gallate from crude green tea extracts by isocratic hydrogen bond adsorption chromatography on beta-cyclodextrin substituted agarose gel media.
Topics: beta-Cyclodextrins; Catechin; Chromatography, High Pressure Liquid; Hydrogen Bonding; Mass Spectrometry; Plant Extracts; Sepharose; Tea | 2005 |
Seasonal variations of phenolic compounds in Australia-grown tea (Camellia sinensis).
Topics: Australia; Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Flavonoids; Flavonols; Phenols; Plant Leaves; Polyphenols; Seasons | 2005 |
Separation of catechin constituents from five tea cultivars using high-speed counter-current chromatography.
Topics: Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Countercurrent Distribution; Nuclear Magnetic Resonance, Biomolecular | 2005 |
Characterization of the oxidase activity in mammalian catalase.
Topics: Animals; Benzidines; Blotting, Western; Catalase; Catechin; Cattle; Cell Line; Coumaric Acids; Cricetinae; Heme; Humans; Hydrogen Peroxide; Indoles; Iron; Kinetics; Laccase; Mice; Mitochondria; Models, Biological; Models, Chemical; Models, Molecular; Oxidoreductases; Oxygen; Peroxidases; Phenethylamines; Protein Binding; Protein Conformation; Spectrophotometry; Temperature; Time Factors; Tryptophan; Vanillic Acid | 2005 |
Bioavailability and antioxidant effect of epigallocatechin gallate administered in purified form versus as green tea extract in healthy individuals.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Antioxidants; Biological Availability; Catechin; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Damage; Flavonols; Guanine; Humans; Lymphocytes; Tea; Uric Acid | 2005 |
Molecular mechanisms of action of angiopreventive anti-oxidants on endothelial cells: microarray gene expression analyses.
Topics: Acetylcysteine; Angiogenesis Inhibitors; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Movement; Cells, Cultured; Endothelial Cells; Free Radical Scavengers; Gene Expression Profiling; Gene Expression Regulation; Humans; NF-kappa B; Oligonucleotide Array Sequence Analysis; Reproducibility of Results; RNA, Messenger; Tumor Necrosis Factor-alpha | 2005 |
Inhibition of survival signalling by dietary polyphenols and indole-3-carbinol.
Topics: Apoptosis; Catechin; Cell Cycle; Curcumin; Flavonoids; Humans; Indoles; Mitogen-Activated Protein Kinases; Neoplasms; NF-kappaB-Inducing Kinase; Phenols; Polyphenols; Protein Serine-Threonine Kinases; Signal Transduction; STAT Transcription Factors | 2005 |
Epigallocatechin-3-gallate suppresses galactose-alpha1,4-galactose-1beta,4-glucose ceramide expression in TNF-alpha stimulated human intestinal epithelial cells through inhibition of MAPKs and NF-kappaB.
Topics: Apoptosis; Blotting, Western; Catechin; Cell Nucleus; Cell Proliferation; Dose-Response Relationship, Drug; Epithelial Cells; Flow Cytometry; Galactosyltransferases; Gene Expression Regulation, Enzymologic; Glucosyltransferases; HT29 Cells; Humans; Intestinal Mucosa; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphorylation; Protein Transport; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trihexosylceramides; Tumor Necrosis Factor-alpha | 2005 |
The effects of epigallocatechin-3-gallate on extracellular matrix metabolism.
Topics: Antioxidants; Catechin; Cells, Cultured; Dermis; Epidermal Cells; Extracellular Matrix; Female; Fibroblasts; Humans; Keratinocytes; Keratolytic Agents; Matrix Metalloproteinases; Oxidative Stress; Tissue Inhibitor of Metalloproteinase-1; Tretinoin; Ultraviolet Rays | 2005 |
Effects of varied EGCG and (+)-catechin concentrations on proinflammatory cytokines mrna expression in cona-stimulated primary white blood cell cultures.
Topics: Animals; Catechin; Cattle; Cells, Cultured; Concanavalin A; Cytokines; Gene Expression; Leukocytes; RNA, Messenger; Tumor Necrosis Factor-alpha | 2005 |
Kinetic study of the quenching reaction of singlet oxygen by tea catechins in ethanol solution.
Topics: Catechin; Catechols; Electrochemistry; Ethanol; Kinetics; Models, Chemical; Nitrogen; Oxidative Stress; Oxygen; Propyl Gallate; Resorcinols; Singlet Oxygen; Tea; Temperature; Time Factors | 2005 |
Protective effects of EGCG on UVB-induced damage in living skin equivalents.
Topics: Apoptosis; Catechin; Cells, Cultured; DNA Damage; Fibroblasts; Humans; Keratinocytes; MAP Kinase Signaling System; Radiation Injuries; Radiation-Protective Agents; Skin; Tissue Engineering; Ultraviolet Rays | 2005 |
[Effect of EGCG on H2O2-induced MnSOD gene expression in cultured spiral ganglion cells].
Topics: Animals; Catechin; Cells, Cultured; Cochlea; Female; Hydrogen Peroxide; Male; Mice; Spiral Ganglion; Superoxide Dismutase | 2004 |
Green tea component, catechin, induces apoptosis of human malignant B cells via production of reactive oxygen species.
Topics: Apoptosis; Arsenic Trioxide; Arsenicals; B-Lymphocytes; bcl-2-Associated X Protein; Caspase 3; Caspases; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Intracellular Membranes; Membrane Potentials; Mitochondria; Multiple Myeloma; Oxides; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Signal Transduction; Tea; Time Factors | 2005 |
Relative ability of dietary compounds to modulate nuclear factor-kappaB activity as assessed in a cell-based reporter system.
Topics: Antioxidants; Ascorbic Acid; Catechin; Dose-Response Relationship, Drug; Flavonoids; HCT116 Cells; Humans; Luciferases; NF-kappa B; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2005 |
Epigallocatechin-3-gallate impairs chemokine production in human colon epithelial cell lines.
Topics: Antioxidants; Catechin; Cell Line, Tumor; Cell Survival; Chemokines; Colon; Colonic Neoplasms; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; HT29 Cells; Humans; Interleukin-8; Kinetics; Macrophage Inflammatory Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha; Up-Regulation | 2005 |
Green tea polyphenol epigallocatechin-3-gallate differentially modulates oxidative stress in PC12 cell compartments.
Topics: Animals; Antioxidants; Blotting, Western; Caspase 3; Caspases; Catechin; Cytochrome P-450 CYP2E1; DNA Fragmentation; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Induction; Glutathione; Lipid Peroxidation; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Subcellular Fractions; Tetrazolium Salts; Thiazoles | 2005 |
HPLC analysis of naturally occurring methylated catechins, 3' '- and 4' '-methyl-epigallocatechin gallate, in various fresh tea leaves and commercial teas and their potent inhibitory effects on inducible nitric oxide synthase in macrophages.
Topics: Camellia sinensis; Catechin; Fermentation; Methylation; Plant Leaves; Seasons; Taiwan | 2005 |
Comparison of (-)-epigallocatechin-3-gallate elicited liver and small intestine gene expression profiles between C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice.
Topics: Animals; Catechin; Gene Expression Profiling; Intestine, Small; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction | 2005 |
Antiviral effect of catechins in green tea on influenza virus.
Topics: Animals; Antiviral Agents; Catechin; Cell Line; Cell Survival; Chickens; Dogs; Enzyme Inhibitors; Erythrocytes; Hemagglutination Inhibition Tests; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Neuraminidase; Reverse Transcriptase Polymerase Chain Reaction; Tea; Tetrazolium Salts; Thiazoles; Viral Plaque Assay; Virus Replication | 2005 |
A lipid raft-associated 67kDa laminin receptor mediates suppressive effect of epigallocatechin-3-O-gallate on FcepsilonRI expression.
Topics: Catechin; Down-Regulation; Humans; Leukemia, Basophilic, Acute; Membrane Microdomains; Molecular Weight; Receptors, IgG; Receptors, Laminin; Tumor Cells, Cultured | 2005 |
Mechanism of action of (-)-epigallocatechin-3-gallate: auto-oxidation-dependent inactivation of epidermal growth factor receptor and direct effects on growth inhibition in human esophageal cancer KYSE 150 cells.
Topics: Benzopyrans; Biflavonoids; Carcinoma, Squamous Cell; Catechin; Cell Growth Processes; Cell Line, Tumor; Drug Stability; ErbB Receptors; Esophageal Neoplasms; Gallic Acid; Humans; Oxidation-Reduction; Phenols; Phosphorylation; Receptor, ErbB-2; Superoxide Dismutase | 2005 |
Epigallocatechin-3-gallate, a polyphenol component of green tea, suppresses both collagen production and collagenase activity in hepatic stellate cells.
Topics: Actins; Animals; Antioxidants; Catechin; Cell Line; Cells, Cultured; Collagen; Collagenases; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression; Humans; Liver; Male; Matrix Metalloproteinase 1; Muscle, Smooth; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tea; Tissue Inhibitor of Metalloproteinase-1 | 2005 |
Inhibitory effects of epigallocatechin gallate on compound 48/80-induced mast cell activation and passive cutaneous anaphylaxis.
Topics: Animals; Antioxidants; Catechin; Cyclic AMP; Histamine Release; Mast Cells; p-Methoxy-N-methylphenethylamine; Passive Cutaneous Anaphylaxis; Rats | 2005 |
Experimental study on anti-neoplastic activity of epigallocatechin-3-gallate to digestive tract carcinomas.
Topics: Antineoplastic Agents; Catechin; Cell Cycle; Cell Line, Tumor; Digestive System Neoplasms; DNA-Binding Proteins; Dose-Response Relationship, Drug; Genes, myc; Genes, p53; Humans; Telomerase | 2005 |
Anti-proliferative effects of green tea polyphenol EGCG on Ha-Ras-induced transformation of intestinal epithelial cells.
Topics: Animals; Anticarcinogenic Agents; Cadherins; Catechin; Cell Cycle; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin D1; Genes, ras; Intestinal Mucosa; Rats; Tea | 2006 |
Inhibitory effect of green tea (-)-epigallocatechin gallate on resistin gene expression in 3T3-L1 adipocytes depends on the ERK pathway.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Catechin; Cell Line; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; MAP Kinase Signaling System; Mice; Resistin; Tea | 2006 |
The antifolate activity of tea catechins.
Topics: Catechin; Folic Acid Antagonists; Tea; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates | 2005 |
Green tea catechin enhances osteogenesis in a bone marrow mesenchymal stem cell line.
Topics: Alkaline Phosphatase; Animals; Antioxidants; Biomarkers; Bone Marrow Cells; Calcification, Physiologic; Camellia sinensis; Catechin; Cell Division; Cell Line; Mesenchymal Stem Cells; Mice; Osteogenesis; Plant Extracts; RNA, Messenger; Thymidine | 2005 |
Interferon-gamma-induced STAT1-mediated membrane retention of NHE1 and associated proteins ezrin, radixin and moesin in HT-29 cells.
Topics: Catechin; Cation Transport Proteins; Cell Membrane; DNA-Binding Proteins; Dose-Response Relationship, Drug; HT29 Cells; Humans; Hydrogen-Ion Concentration; Interferon-gamma; Membrane Proteins; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; STAT1 Transcription Factor; Transcription Factors | 2005 |
Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Catechin; Cells, Cultured; Female; Flavonoids; Mice; Mice, Transgenic; Tea | 2005 |
Comparison of green tea extract and epigallocatechin gallate on secretion of catecholamines from the rabbit adrenal medulla.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adrenal Medulla; Animals; Calcium Channel Agonists; Catechin; Catecholamines; Dimethylphenylpiperazinium Iodide; Extracellular Fluid; Korea; Male; Muscarinic Agonists; Nicotinic Agonists; Perfusion; Plant Extracts; Plant Leaves; Potassium; Rabbits; Tea; Time Factors | 2005 |
Epigallocatechin gallate modulates cytokine production by bone marrow-derived dendritic cells stimulated with lipopolysaccharide or muramyldipeptide, or infected with Legionella pneumophila.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Bone Marrow Cells; Catechin; Cytokines; Dendritic Cells; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Immunity, Innate; Legionella pneumophila; Lipopolysaccharides; Mice; Mice, Inbred BALB C | 2005 |
The main catechin of green tea, (-)-epigallocatechin-3-gallate (EGCG), reduces bleomycin-induced DNA damage in human leucocytes.
Topics: Antibiotics, Antineoplastic; Bleomycin; Catechin; Comet Assay; Deoxyribonucleases, Type III Site-Specific; DNA Damage; Humans; In Vitro Techniques; Leukocytes; Phytohemagglutinins | 2006 |
Epigallocatechin gallate inhibits biofilm formation by ocular staphylococcal isolates.
Topics: Anti-Bacterial Agents; Biofilms; Catechin; Eye; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus epidermidis | 2005 |
Modulation of MPP+ uptake by tea and some of its components in Caco-2 cells.
Topics: 1-Methyl-4-phenylpyridinium; Caco-2 Cells; Caffeine; Catechin; Corticosterone; Food-Drug Interactions; Humans; Intestinal Absorption; Intestinal Mucosa; Organic Cation Transport Proteins; Plant Extracts; Quinolines; Tea; Theophylline; Tritium | 2005 |
[Effect of tea polyphenols on oxidative metabolism of polymorphonuclear neutrophils in healthy and obese people].
Topics: Adult; Antioxidants; Biflavonoids; C-Reactive Protein; Case-Control Studies; Catechin; Female; Flavonoids; Gallic Acid; Humans; Hydrogen Peroxide; In Vitro Techniques; Luminescence; Male; Middle Aged; Neutrophils; Nitric Oxide; Obesity; Oxidative Stress; Phenols; Polyphenols; Reactive Oxygen Species; Tea; Tetradecanoylphorbol Acetate | 2005 |
Dose-dependent levels of epigallocatechin-3-gallate in human colon cancer cells and mouse plasma and tissues.
Topics: Administration, Oral; Animals; Camellia sinensis; Catechin; Colon; Dose-Response Relationship, Drug; HT29 Cells; Humans; Intestine, Small; Liver; Male; Mice; Prostate; Rats; Tissue Distribution | 2006 |
Comparative effects of 2 antioxidants, selenomethionine and epigallocatechin-gallate, on catabolic and anabolic gene expression of articular chondrocytes.
Topics: Animals; Antioxidants; Cartilage, Articular; Catechin; Cattle; Cells, Cultured; Chondrocytes; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Enzymes; Extracellular Matrix; Gene Expression; Interleukin-1; NF-kappa B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selenomethionine; Transcription Factor AP-1 | 2005 |
UV-induced NF-kappaB activation and expression of IL-6 is attenuated by (-)-epigallocatechin-3-gallate in cultured human keratinocytes in vitro.
Topics: Apoptosis; Catechin; Down-Regulation; Fas Ligand Protein; Humans; Interleukin-6; Keratinocytes; Membrane Glycoproteins; NF-kappa B; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Radiation-Protective Agents; Transcription Factor RelA; Tumor Necrosis Factors; Ultraviolet Rays | 2005 |
Immune cell activation and subsequent epithelial dysfunction by Staphylococcus enterotoxin B is attenuated by the green tea polyphenol (-)-epigallocatechin gallate.
Topics: Animals; Anti-Inflammatory Agents; Camellia sinensis; Catechin; Cell Proliferation; Cytokines; Electrophoretic Mobility Shift Assay; Enterotoxins; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Humans; Immunoblotting; Interleukin-2; Lymphocyte Activation; Lymphocytes; Mice; NF-kappa B; Plant Extracts; Transcription Factor AP-1 | 2005 |
Inhibitory modulation of ATP-sensitive potassium channels by gallate-ester moiety of (-)-epigallocatechin-3-gallate.
Topics: Adenosine Triphosphate; Animals; Catechin; Cell Membrane; Ion Channel Gating; Islets of Langerhans; Membrane Potentials; Molecular Structure; Oocytes; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Protein Subunits; Structure-Activity Relationship; Xenopus laevis | 2005 |
Green tea catechin, epigallocatechin-3-gallate, inhibits vascular endothelial growth factor angiogenic signaling by disrupting the formation of a receptor complex.
Topics: Catechin; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Neoplasms; Neovascularization, Pathologic; Phosphatidylinositol 3-Kinases; Signal Transduction; Tea; Umbilical Veins; Vascular Endothelial Growth Factor A | 2006 |
Epigallocatechin gallate increases the formation of cytosolic lipid droplets and decreases the secretion of apoB-100 VLDL.
Topics: Adipocytes; Animals; Apolipoprotein B-100; Apolipoproteins B; Base Sequence; Catechin; Cell Line; Cytosol; DNA, Complementary; Heparin; Humans; Lipid Metabolism; Lipids; Lipoproteins; Lipoproteins, VLDL; Membrane Proteins; Mice; Mice, Transgenic; NIH 3T3 Cells; Perilipin-2; Rats; Receptors, LDL; Recombinant Proteins | 2006 |
Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Transitional Cell; Catechin; Cell Line, Tumor; Colorectal Neoplasms; Cytidine; Decitabine; Deoxycytidine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Silencing; HT29 Cells; Humans; Hydralazine; Male; Procainamide; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction | 2005 |
Genistein, EGCG, and capsaicin inhibit adipocyte differentiation process via activating AMP-activated protein kinase.
Topics: 3T3-L1 Cells; Adipocytes; AMP-Activated Protein Kinases; Animals; Capsaicin; Catechin; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Activation; Genistein; Mice; Multienzyme Complexes; Protein Serine-Threonine Kinases | 2005 |
Transdermal delivery of tea catechins by electrically assisted methods.
Topics: Administration, Cutaneous; Animals; Catechin; Electric Conductivity; Electroporation; In Vitro Techniques; Iontophoresis; Liposomes; Skin Absorption; Swine; Tea | 2006 |
Effect of some phenolic compounds and beverages on pepsin activity during simulated gastric digestion.
Topics: Animals; Caseins; Catechin; Digestion; Enzyme Activation; Flavonoids; Gastric Mucosa; Hemoglobins; Kinetics; Meat; Pepsin A; Phenols; Polyphenols; Protein Denaturation; Quercetin; Resveratrol; Stilbenes; Swine; Tea; Wine | 2005 |
Cytotoxicity and cytoprotective activity in naphthalenediols depends on their tendency to form naphthoquinones.
Topics: Animals; Antioxidants; Catechin; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Free Radicals; Hot Temperature; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Models, Chemical; Naphthols; Naphthoquinones; Oxidation-Reduction; Oxidative Stress; Quinones; Rats; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Use of cancer chemopreventive phytochemicals as antineoplastic agents.
Topics: Antineoplastic Agents, Phytogenic; Catechin; Curcumin; Humans; Neoplasms | 2005 |
Inhibition of intestinal tumorigenesis in Apcmin/+ mice by (-)-epigallocatechin-3-gallate, the major catechin in green tea.
Topics: Animals; Anticarcinogenic Agents; beta Catenin; Cadherins; Caffeine; Catechin; Dinoprostone; Extracellular Signal-Regulated MAP Kinases; Female; Genes, APC; HT29 Cells; Humans; Intestinal Neoplasms; Intestine, Small; Leukotriene B4; Male; Mice; Mice, Inbred C57BL; Phospholipases A; Phosphorylation; Proto-Oncogene Proteins c-akt | 2005 |
In vitro cytotoxicity of a theaflavin mixture from black tea to malignant, immortalized, and normal cells from the human oral cavity.
Topics: Biflavonoids; Catechin; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Glutathione; Humans; Hydrogen Peroxide; Plant Extracts; Tea | 2006 |
Attenuation of intestinal ischemia/reperfusion induced liver and lung injury by intraperitoneal administration of (-)-epigallocatechin-3-gallate.
Topics: Animals; Catechin; Intestinal Mucosa; Ischemia; Lipid Peroxidation; Liver; Lung; Male; Malondialdehyde; Microscopy, Electron; Microscopy, Polarization; Rats; Rats, Wistar; Reperfusion Injury | 2006 |
Study of the mechanisms involved in the vasorelaxation induced by (-)-epigallocatechin-3-gallate in rat aorta.
Topics: Angiotensin II; Animals; Aorta; Calcium; Catechin; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Male; Norepinephrine; Phosphodiesterase Inhibitors; Rats; Rats, Inbred WKY; Vasodilation | 2006 |
Synthesis and structure identification of thiol conjugates of (-)-epigallocatechin gallate and their urinary levels in mice.
Topics: Adult; Animals; Catechin; Cysteine; Humans; Magnetic Resonance Spectroscopy; Male; Mice; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds | 2005 |
Stability of tea polyphenol (-)-epigallocatechin-3-gallate and formation of dimers and epimers under common experimental conditions.
Topics: Benzopyrans; Catechin; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dimerization; Drug Stability; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxidation-Reduction; Phenols; Tea | 2005 |
Dual function of (--)-epigallocatechin gallate (EGCG) in healthy human lymphocytes.
Topics: Adult; Antioxidants; Bleomycin; Catechin; DNA Damage; Free Radical Scavengers; Humans; Hydrogen Peroxide; Lymphocytes; Male; Oxidants; Oxidation-Reduction | 2006 |
Regulation of p53 by activated protein kinase C-delta during nitric oxide-induced dopaminergic cell death.
Topics: Animals; Apoptosis; Catechin; Cell Death; Cell Line; Cell Survival; Coculture Techniques; Dopamine; Enzyme Activation; Immunoblotting; Immunohistochemistry; Immunoprecipitation; In Situ Nick-End Labeling; Mice; Microglia; Models, Biological; Nitric Oxide; Nitrites; Nitroprusside; Parkinson Disease; Phosphorylation; Proteasome Endopeptidase Complex; Protein Kinase C-delta; Proto-Oncogene Proteins c-mdm2; Serine; Time Factors; Tumor Suppressor Protein p53 | 2006 |
Green tea polyphenol epigallocatechin-3 gallate (EGCG) affects gene expression of breast cancer cells transformed by the carcinogen 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anticarcinogenic Agents; Breast Neoplasms; Carcinogens; Catechin; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2005 |
Clinical effects of oral green tea extracts in four patients with low grade B-cell malignancies.
Topics: Anticarcinogenic Agents; Camellia sinensis; Catechin; Clinical Trials as Topic; Disease-Free Survival; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Neoplasm Regression, Spontaneous; Neoplasm Staging; Phytotherapy; Plant Extracts; Radiography; Remission Induction; Tea | 2006 |
Apple- and hop-polyphenols protect periodontal ligament cells stimulated with enamel matrix derivative from Porphyromonas gingivalis.
Topics: Adhesins, Bacterial; Catechin; Cell Line; Cell Movement; Cell Proliferation; Cell Survival; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dental Enamel Proteins; Flavonoids; Gingipain Cysteine Endopeptidases; Humans; Humulus; Malus; Periodontal Ligament; Phenols; Polyphenols; Porphyromonas gingivalis; Proanthocyanidins; Protease Inhibitors; Urokinase-Type Plasminogen Activator | 2005 |
Natural products and the treatment of leukemia.
Topics: Anticarcinogenic Agents; Camellia sinensis; Catechin; Clinical Trials as Topic; Disease-Free Survival; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Neoplasm Regression, Spontaneous; Neoplasm Staging; Phytotherapy; Plant Extracts; Radiography; Remission Induction; Tea | 2006 |
Green tea polyphenol inhibits Mycobacterium tuberculosis survival within human macrophages.
Topics: Antioxidants; Camellia sinensis; Catechin; Colony Count, Microbial; Down-Regulation; Flavonoids; Flow Cytometry; Humans; Jurkat Cells; Macrophages; Microfilament Proteins; Mycobacterium tuberculosis; Phenols; Plant Extracts; Polyphenols; Sp1 Transcription Factor; Tuberculosis | 2006 |
Involvement of Nrf2, p38, B-Raf, and nuclear factor-kappaB, but not phosphatidylinositol 3-kinase, in induction of hemeoxygenase-1 by dietary polyphenols.
Topics: Animals; Apoptosis; B-Lymphocytes; Breast; Catechin; Cell Nucleus; Cells, Cultured; Curcumin; Diet; Fibroblasts; Flavonoids; Heme Oxygenase-1; Humans; Mice; Mice, Knockout; NF-E2-Related Factor 2; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phenols; Phosphatidylinositol 3-Kinases; Polyphenols; Sesquiterpenes; Sesquiterpenes, Guaiane | 2006 |
The effect of epigallocatechin gallate on suppressing disease progression of ALS model mice.
Topics: Amyotrophic Lateral Sclerosis; Animals; Blotting, Western; Caspase 3; Caspases; Catechin; Disease Models, Animal; Disease Progression; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mice; Mice, Transgenic; Motor Activity; Mutation; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1 | 2006 |
Safety studies on epigallocatechin gallate (EGCG) preparations. Part 1: genotoxicity.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Biological Assay; Camellia sinensis; Catechin; Consumer Product Safety; Dose-Response Relationship, Drug; Female; Humans; Hydrogen Peroxide; Male; Mice; Mice, Inbred Strains; Micronucleus Tests; Mutagenicity Tests; Rats; Rats, Wistar; Salmonella; Tumor Cells, Cultured | 2006 |
Tea polyphenol epigallocatechin 3-gallate impedes the anti-apoptotic effects of low-grade repetitive stress through inhibition of Akt and NFkappaB survival pathways.
Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Antioxidants; Apoptosis; Catechin; Cells, Cultured; Chromones; Cricetinae; Cricetulus; Enzyme Inhibitors; Fibroblasts; Humans; Hydrogen Peroxide; Lung; Morpholines; NF-kappa B; Oxidants; Oxidative Stress; Peptides; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Tea; Ultraviolet Rays | 2006 |
Upregulation of heme oxygenase-1 by Epigallocatechin-3-gallate via the phosphatidylinositol 3-kinase/Akt and ERK pathways.
Topics: Animals; Antioxidants; Catechin; Cattle; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Heme Oxygenase-1; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction; Up-Regulation | 2006 |
Safety studies on epigallocatechin gallate (EGCG) preparations. Part 2: dermal, acute and short-term toxicity studies.
Topics: Administration, Oral; Administration, Topical; Animals; Antioxidants; Area Under Curve; Camellia sinensis; Catechin; Dermatitis, Allergic Contact; Dogs; Dose-Response Relationship, Drug; Eye; Fasting; Female; Guinea Pigs; Male; No-Observed-Adverse-Effect Level; Rabbits; Random Allocation; Rats; Sex Factors; Skin Absorption; Species Specificity; Toxicity Tests, Acute | 2006 |
Inhibition of CWR22Rnu1 tumor growth and PSA secretion in athymic nude mice by green and black teas.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Biflavonoids; Catechin; Flavonoids; Male; Mice; Mice, Nude; Phenols; Polyphenols; Prostate-Specific Antigen; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Tea; Up-Regulation | 2006 |
Increase of MMP-13 expression in multi-stage oral carcinogenesis and epigallocatechin-3-gallate suppress MMP-13 expression.
Topics: Adult; Aged; Anticarcinogenic Agents; Blotting, Western; Carcinoma, Squamous Cell; Catechin; Collagenases; Electrophoresis, Polyacrylamide Gel; Humans; Immunohistochemistry; Matrix Metalloproteinase 13; Matrix Metalloproteinase Inhibitors; Middle Aged; Mouth Neoplasms; Neoplasm Staging; Protease Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2006 |
beta-Secretase (BACE1) inhibitors from pomegranate (Punica granatum) husk.
Topics: Acetates; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Butanols; Catechin; Dose-Response Relationship, Drug; Ellagic Acid; Endopeptidases; Enzyme Inhibitors; Fruit; Humans; Hydrolyzable Tannins; Lythraceae; Plant Extracts; Plants, Medicinal; Substrate Specificity | 2005 |
Epigallocatechin-3-gallate delivers hydrogen peroxide to induce death of ovarian cancer cells and enhances their cisplatin susceptibility.
Topics: Antineoplastic Agents; Antioxidants; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Cyclic N-Oxides; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Female; Fluoresceins; Humans; Hydrogen Peroxide; Ovarian Neoplasms; Pyruvic Acid; Spin Labels | 2006 |
Green tea extract and its major polyphenol (-)-epigallocatechin gallate improve muscle function in a mouse model for Duchenne muscular dystrophy.
Topics: Animals; Antioxidants; Camellia sinensis; Catechin; Diet; Disease Models, Animal; Free Radical Scavengers; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle Contraction; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Pentoxifylline; Phytotherapy; Plant Extracts; Plant Preparations | 2006 |
Searching for aging-related proteins in human dermal microvascular endothelial cells treated with anti-aging agents.
Topics: Aging; Antioxidants; Biomarkers; Blotting, Western; Catechin; Cells, Cultured; Dermis; Electrophoresis, Gel, Two-Dimensional; Endothelium, Vascular; Humans; Kinetin; Peptide Mapping; Plant Growth Regulators; Propidium; Proteome; Selenium; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thymidine | 2006 |
Safety studies on epigallocatechin gallate (EGCG) preparations. Part 3: teratogenicity and reproductive toxicity studies in rats.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Animals, Newborn; Anticarcinogenic Agents; Antimutagenic Agents; Catechin; Dose-Response Relationship, Drug; Female; Fetus; Injections, Subcutaneous; Litter Size; Male; No-Observed-Adverse-Effect Level; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reproduction; Teratogens | 2006 |
The Survivin-mediated radioresistant phenotype of glioblastomas is regulated by RhoA and inhibited by the green tea polyphenol (-)-epigallocatechin-3-gallate.
Topics: Anticarcinogenic Agents; Blotting, Western; Caspase 3; Caspases; Catechin; Caveolin 1; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Fluorescent Antibody Technique; Gene Expression; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Neoplasm Proteins; Phenotype; Probability; rhoA GTP-Binding Protein; Survivin; Transfection | 2006 |
Catechin derivatives: specific inhibitor for caspases-3, 7 and 2, and the prevention of apoptosis at the cell and animal levels.
Topics: Animals; Apoptosis; Caspase 2; Caspase 3; Caspase 7; Caspase Inhibitors; Caspases; Catechin; Cell-Free System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Galactosamine; HeLa Cells; Hepatocytes; Humans; In Situ Nick-End Labeling; Rats | 2006 |
A yeast-based model of alpha-synucleinopathy identifies compounds with therapeutic potential.
Topics: alpha-Synuclein; Brain Diseases; Caspase Inhibitors; Caspases; Catechin; Flavonoids; Humans; Metals; Models, Biological; Molecular Structure; Neuroprotective Agents; Recombinant Fusion Proteins; Risk Factors; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2006 |
Enhancement of the transdermal delivery of catechins by liposomes incorporating anionic surfactants and ethanol.
Topics: Administration, Cutaneous; Animals; Antioxidants; Catechin; Chemistry, Pharmaceutical; Deoxycholic Acid; Drug Compounding; Ethanol; Female; Liposomes; Mice; Mice, Inbred BALB C; Organophosphates; Particle Size; Permeability; Skin; Skin Absorption; Surface-Active Agents; Water | 2006 |
EGCG inhibits activation of HER3 and expression of cyclooxygenase-2 in human colon cancer cells.
Topics: bcl-X Protein; Biotransformation; Blotting, Western; Catechin; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Dinoprostone; DNA Fragmentation; Enzyme Induction; ErbB Receptors; Genes, erbB-2; Genes, Reporter; Humans; Immunoprecipitation; NF-kappa B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Transcription Factor AP-1 | 2005 |
Effect of liposome encapsulation of tea catechins on their accumulation in basal cell carcinomas.
Topics: Animals; Antineoplastic Agents; Carcinoma, Basal Cell; Catechin; Cell Line, Tumor; Deoxycholic Acid; Drug Delivery Systems; Ethanol; Female; Humans; Liposomes; Melanoma; Mice; Mice, Inbred BALB C; Tea | 2006 |
Apoptosis induction by Epican Forte in HTLV-1 positive and negative malignant T-cells.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Arginine; Ascorbic Acid; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Copper; Dietary Supplements; DNA; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression Profiling; Human T-lymphotropic virus 1; Humans; Lysine; Manganese; Proline; Reverse Transcriptase Polymerase Chain Reaction; Selenium; Sensitivity and Specificity; Structure-Activity Relationship; T-Lymphocytes; Transforming Growth Factors | 2006 |
Green tea polyphenol (-)-epigallocatechin-3-gallate inhibits ethanol-induced activation of pancreatic stellate cells.
Topics: Actins; Animals; Antioxidants; Camellia sinensis; Catechin; Cell Membrane; Cells, Cultured; Collagen; Collagen Type I; Ethanol; Flavonoids; Gene Expression; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pancreas; Phenols; Polyphenols; Rats; Rats, Wistar; Superoxide Dismutase; Transforming Growth Factor beta | 2006 |
Rational design of anticytoadherence inhibitors for Plasmodium falciparum based on the crystal structure of human intercellular adhesion molecule 1.
Topics: Animals; Antimalarials; Binding Sites; Catechin; Cell Adhesion; Cell Line; Crystallization; Drug Design; Erythrocytes; Humans; Intercellular Adhesion Molecule-1; Plasmodium falciparum | 2006 |
Potentiation of catechin gallate-mediated sensitization of Staphylococcus aureus to oxacillin by nongalloylated catechins.
Topics: Catechin; Drug Synergism; Microbial Sensitivity Tests; Oxacillin; Staphylococcus aureus | 2006 |
Epigallocatechin gallate reduces hypoxia-induced apoptosis in human hepatoma cells.
Topics: Antigens, Neoplasm; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cadherins; Carcinoma, Hepatocellular; Catechin; Cell Adhesion Molecules; Cell Hypoxia; Cell Line, Tumor; Coloring Agents; Epithelial Cell Adhesion Molecule; Genes, bcl-2; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Liver Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2006 |
The green tea catechins, (-)-Epigallocatechin-3-gallate (EGCG) and (-)-Epicatechin-3-gallate (ECG), inhibit HGF/Met signaling in immortalized and tumorigenic breast epithelial cells.
Topics: Antioxidants; Breast; Breast Neoplasms; Catechin; Dose-Response Relationship, Drug; Female; Hepatocyte Growth Factor; Humans; Neoplasm Invasiveness; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Receptors, Growth Factor; Signal Transduction; Tumor Cells, Cultured | 2006 |
(-)-Epigallocatechin gallate attenuates acute stress responses through GABAergic system in the brain.
Topics: Animals; Antioxidants; Brain; Catechin; Chickens; Corticosterone; Dose-Response Relationship, Drug; GABA Antagonists; GABA-B Receptor Antagonists; Injections, Intraventricular; Male; Organophosphorus Compounds; Picrotoxin; Receptors, GABA-B; Stress, Psychological; Vocalization, Animal | 2006 |
Cellular and in vivo hepatotoxicity caused by green tea phenolic acids and catechins.
Topics: Alanine Transaminase; Animals; Antioxidants; Catechin; Gallic Acid; Glutathione; Hydroxybenzoates; Iron; Liver; Male; Mass Spectrometry; Methylation; Mice; NAD(P)H Dehydrogenase (Quinone); Rats; Rats, Sprague-Dawley; Tea | 2006 |
The repressive effect of green tea ingredients on amyloid precursor protein (APP) expression in oral carcinoma cells in vitro and in vivo.
Topics: Amyloid beta-Protein Precursor; Animals; Blotting, Western; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Phytotherapy; Plant Preparations; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tea | 2007 |
Green tea polyphenol stimulates cancer preventive effects of celecoxib in human lung cancer cells by upregulation of GADD153 gene.
Topics: Anticarcinogenic Agents; Blotting, Western; Catechin; Celecoxib; Cell Line, Tumor; Cyclooxygenase Inhibitors; Drug Synergism; Flavonoids; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mitogen-Activated Protein Kinase Kinases; Phenols; Plant Extracts; Polymerase Chain Reaction; Polyphenols; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Tea; Transcription Factor CHOP; Up-Regulation | 2006 |
How can (-)-epigallocatechin gallate from green tea prevent HIV-1 infection? Mechanistic insights from computational modeling and the implication for rational design of anti-HIV-1 entry inhibitors.
Topics: Anti-HIV Agents; Binding Sites; Catechin; CD4-Positive T-Lymphocytes; Computer Simulation; Drug Design; HIV Envelope Protein gp120; HIV Infections; HIV-1; Ligands; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Protein Structure, Tertiary; Stereoisomerism; Structure-Activity Relationship; Tea; Time Factors | 2006 |
Synthesis, structure analyses, and characterization of novel epigallocatechin gallate (EGCG) glycosides using the glucansucrase from Leuconostoc mesenteroides B-1299CB.
Topics: Antioxidants; Catechin; Glycosides; Glycosylation; Glycosyltransferases; Leuconostoc; Molecular Structure; Solubility; Sucrose; Water | 2006 |
A green tea polyphenol, epigalocatechin-3-gallate, induces apoptosis of human hepatocellular carcinoma, possibly through inhibition of Bcl-2 family proteins.
Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; bcl-X Protein; Camellia sinensis; Carcinoma, Hepatocellular; Caspases; Catechin; Cell Line, Tumor; Down-Regulation; Enzyme Activation; Humans; Liver Neoplasms; Male; Membrane Glycoproteins; Mice; Mice, Inbred Strains; RNA, Messenger; Tea; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha; Xenograft Model Antitumor Assays | 2006 |
Suppression of Wnt signaling by the green tea compound (-)-epigallocatechin 3-gallate (EGCG) in invasive breast cancer cells. Requirement of the transcriptional repressor HBP1.
Topics: Blotting, Western; Breast Neoplasms; Catechin; Cell Line; Cell Line, Tumor; Cell Movement; Dactinomycin; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Genes, Reporter; High Mobility Group Proteins; Humans; Models, Biological; Phosphorylation; Plasmids; Proto-Oncogene Proteins c-myc; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Signal Transduction; Tea; Time Factors; Transcription, Genetic; Transfection; Wnt Proteins | 2006 |
Modulation of cholesterol metabolism by the green tea polyphenol (-)-epigallocatechin gallate in cultured human liver (HepG2) cells.
Topics: Camellia sinensis; Catechin; Cell Line, Tumor; Chenodeoxycholic Acid; Cholesterol; Dose-Response Relationship, Drug; Humans; Lanosterol; Liver; Plant Leaves; Receptors, LDL; Sterol Regulatory Element Binding Protein 1 | 2006 |
Green tea polyphenol epigallocatechin-3-gallate protects cells against peroxynitrite-induced cytotoxicity: modulatory effect of cellular G6PD status.
Topics: Apoptosis; Camellia sinensis; Catechin; Cell Line; Cell Survival; Fibroblasts; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Deficiency; Glutathione; Humans; Molsidomine; Oxidation-Reduction; Peroxynitrous Acid; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Tumor Suppressor Protein p53 | 2006 |
Green tea polyphenol (-)-epigallocatechin-3-gallate inhibits cyclooxygenase-2 expression in colon carcinogenesis.
Topics: Blotting, Western; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Enzyme Induction; Gene Expression Regulation, Enzymologic; Genes, Reporter; Humans; MAP Kinase Signaling System; NF-kappa B; Phosphatidylinositol 3-Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tea | 2006 |
Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines.
Topics: Azacitidine; Catechin; Cell Line, Tumor; Cytidine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Humans; Indoles; Jurkat Cells; Phthalimides; Procaine; Propionates; Tryptophan | 2006 |
Epigallocatechin-3-gallate protects toluene diisocyanate-induced airway inflammation in a murine model of asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Catechin; Disease Models, Animal; Gene Expression Regulation; Inflammation; Interleukin-5; Matrix Metalloproteinase 9; Mice; Reactive Oxygen Species; Respiratory System; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha | 2006 |
Transgenic mouse line overexpressing the cancer-specific tNOX protein has an enhanced growth and acquired drug-response phenotype.
Topics: Animals; Body Weight; Catechin; Cell Membrane; Gene Expression; Gene Expression Regulation, Enzymologic; Genetic Vectors; Genotype; Mice; Mice, Transgenic; NADH, NADPH Oxidoreductases; Phenotype; RNA-Directed DNA Polymerase; RNA, Messenger; Spectrophotometry; Survival Rate; Toxicity Tests, Acute | 2006 |
Green tea polyphenols and its constituent epigallocatechin gallate inhibits proliferation of human breast cancer cells in vitro and in vivo.
Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Catechin; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Female; Flavonoids; G1 Phase; Guanosine Triphosphate; Humans; Immunohistochemistry; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Phenols; Polyphenols; Proliferating Cell Nuclear Antigen; Tea; Xenograft Model Antitumor Assays | 2007 |
Effect of long-term oral administration of green tea extract on weight gain and glucose tolerance in Zucker diabetic (ZDF) rats.
Topics: Administration, Oral; Analysis of Variance; Animals; Body Weight; Catechin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Administration Schedule; Eating; Glucose; Glucose Intolerance; Hypoglycemic Agents; Male; Plant Extracts; Rats; Rats, Zucker; Tea | 2005 |
Epigallocatechin-3-gallate reduces allergen-induced asthma-like reaction in sensitized guinea pigs.
Topics: Allergens; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Catechin; Disease Models, Animal; Guinea Pigs; Lung; Male; Nitric Oxide Synthase; Ovalbumin | 2006 |
Green tea polyphenol epigallocatechin-3-gallate inhibits the expression of nitric oxide synthase and generation of nitric oxide induced by ultraviolet B in HaCaT cells.
Topics: Catechin; Cells, Cultured; Gene Expression Regulation, Enzymologic; Humans; Keratinocytes; Nitric Oxide; Nitric Oxide Synthase Type II; Protein Transport; RNA, Messenger; Tea; Transcription Factor RelA; Ultraviolet Rays | 2006 |
Reduction of iron-regulated amyloid precursor protein and beta-amyloid peptide by (-)-epigallocatechin-3-gallate in cell cultures: implications for iron chelation in Alzheimer's disease.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antigens, CD; Blotting, Western; Catechin; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Deferoxamine; Dose-Response Relationship, Drug; Drug Interactions; Electrophoresis, Gel, Two-Dimensional; Gene Expression; Humans; Immunoprecipitation; Iron; Iron Chelating Agents; Neuroblastoma; Neuroprotective Agents; Receptors, Transferrin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection | 2006 |
Inhibitory effect of Salvia miltiorrhia BGE on matrix metalloproteinase-9 activity and migration of TNF-alpha-induced human aortic smooth muscle cells.
Topics: Aorta; Catechin; Cell Movement; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Humans; Inhibitory Concentration 50; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Myocytes, Smooth Muscle; Plant Extracts; Plant Roots; Plant Stems; Protease Inhibitors; Salvia miltiorrhiza; Tumor Necrosis Factor-alpha | 2006 |
Long-term administration of green tea catechins improves spatial cognition learning ability in rats.
Topics: Animals; Antioxidants; Catechin; Cognition; Ferric Compounds; Hippocampus; Learning; Lipid Peroxides; Male; Memory; Oxidation-Reduction; Rats; Rats, Wistar; Reactive Oxygen Species; Space Perception; Tea | 2006 |
(+)-Catechin prevents ultraviolet B-induced human keratinocyte death via inhibition of JNK phosphorylation.
Topics: Catechin; Cell Death; Cell Line; Cells, Cultured; Enzyme Activation; Humans; Hydrogen Peroxide; Keratinocytes; MAP Kinase Kinase 4; Phosphorylation; Ultraviolet Rays | 2006 |
Tea polyphenol epigallocatechin-3-gallate inhibits ergosterol synthesis by disturbing folic acid metabolism in Candida albicans.
Topics: Antifungal Agents; Azoles; Candida albicans; Candidiasis; Catechin; Drug Synergism; Enzyme Inhibitors; Ergosterol; Folic Acid; Folic Acid Antagonists; Fungal Proteins; Leucovorin; Microbial Sensitivity Tests; Models, Biological; Naphthalenes; S-Adenosylmethionine; Spectrum Analysis; Terbinafine; Tetrahydrofolate Dehydrogenase; Vitamin B Complex | 2006 |
Protection of peroxynitrite-induced DNA damage by dietary antioxidants.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Catechin; Deoxyguanosine; Diet; DNA; DNA Damage; Free Radical Scavengers; Humans; Molsidomine; Peroxynitrous Acid; Resveratrol; Stilbenes; Triterpenes; U937 Cells; Ursolic Acid | 2006 |
Electrofocusing of methanolic extracts for identification of individual flavonol biomolecules in Camellia species.
Topics: Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Flavonols; Isoelectric Focusing; Methanol; Plant Extracts; Plant Leaves; Spectrophotometry | 2006 |
Catechin-vanilloid synergies with potential clinical applications in cancer.
Topics: Animals; Anticarcinogenic Agents; Camellia sinensis; Capsaicin; Catechin; Cell Line, Tumor; Drug Synergism; Female; HeLa Cells; Humans; Mice; Mice, Inbred BALB C; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Neoplasm Proteins; Plant Extracts | 2006 |
Prevention of ultraviolet radiation-induced immunosuppression by (-)-epigallocatechin-3-gallate in mice is mediated through interleukin 12-dependent DNA repair.
Topics: Administration, Topical; Animals; Anticarcinogenic Agents; Catechin; Cells, Cultured; DNA Repair; Genotype; Humans; Immune System; Immune Tolerance; Interleukin-12; Mice; Mice, Inbred C3H; Mice, Knockout; Sensitivity and Specificity; Ultraviolet Rays | 2006 |
High tea consumption diminishes salivary 17beta-estradiol concentration in Polish women.
Topics: Adult; Body Mass Index; Catechin; Drinking; Estradiol; Feeding Behavior; Female; Humans; Menstrual Cycle; Motor Activity; Poland; Reproductive History; Rural Health; Saliva; Tea; Urban Health | 2006 |
[The role of NF-E2-related factor 2 in the induction of uridine 5'-diphosphate-glucuronosyltransferase 1A and its isoforms by epigallocatechin gallate in colon cancer cells].
Topics: Blotting, Western; Caco-2 Cells; Catechin; Colonic Neoplasms; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glucuronosyltransferase; HT29 Cells; Humans; Immunohistochemistry; Microscopy, Confocal; NF-E2-Related Factor 2; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; Transfection | 2006 |
Epigallocatechin gallate protects dopaminergic neurons against 1-methyl-4- phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity by inhibiting microglial cell activation.
Topics: Animals; Catechin; Dopamine; Male; Mesencephalon; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neuroglia; Neurons; Neuroprotective Agents; Parkinson Disease; Substantia Nigra; Tea | 2006 |
ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Catechin; Endopeptidases; Female; Male; Mice; Mice, Inbred C57BL; Protein Structure, Tertiary; RNA, Small Interfering; Tea | 2006 |
Differential regulation of NF-kappaB activation and function by topoisomerase II inhibitors.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Catechin; Cell Line, Tumor; Daunorubicin; DNA Damage; Doxorubicin; Enzyme Inhibitors; Free Radicals; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Intercalating Agents; Mitoxantrone; NF-kappa B; Osteosarcoma; Oxidation-Reduction; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; Topoisomerase II Inhibitors; Transcription, Genetic | 2006 |
Determination of the predominant catechins in Acacia catechu by liquid chromatography/electrospray ionization-mass spectrometry.
Topics: Acacia; Camellia sinensis; Catechin; Chromatography, Liquid; Plant Leaves; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2006 |
Transdermal delivery of (-)-epigallocatechin-3-gallate, a green tea polyphenol, in mice.
Topics: Administration, Cutaneous; Animals; Biological Availability; Camellia sinensis; Catechin; Chemistry, Pharmaceutical; Delayed-Action Preparations; Dermis; Drug Stability; Epidermis; Female; Gels; Mice; Skin Absorption; Tissue Distribution | 2006 |
DNA and RNA as new binding targets of green tea catechins.
Topics: Apoptosis; Catechin; DNA; DNA Damage; DNA, Single-Stranded; Free Radical Scavengers; Models, Chemical; Models, Molecular; Nucleotides; RNA; Spectrometry, Mass, Electrospray Ionization; Surface Plasmon Resonance; Tea; Temperature | 2006 |
Inhibitory effects of epigallocatechin-3-O-gallate on serum-stimulated rat aortic smooth muscle cells via nuclear factor-kappaB down-modulation.
Topics: Animals; Antioxidants; Aorta; Catechin; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Myocytes, Smooth Muscle; NF-kappa B; Rats; Serum | 2006 |
The antifibrogenic effect of (-)-epigallocatechin gallate results from the induction of de novo synthesis of glutathione in passaged rat hepatic stellate cells.
Topics: Animals; Antioxidants; Catechin; Cell Culture Techniques; Cells, Cultured; Connective Tissue Growth Factor; Culture Media; Dose-Response Relationship, Drug; Extracellular Matrix; Fibrinogen; Fibrosis; Glutathione; Hepatocytes; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Lipid Peroxidation; Liver; Male; Procollagen; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Transforming Growth Factor beta; Signal Transduction; Tea; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2006 |
Modulators of cigarette smoke-induced pulmonary emphysema in A/J mice.
Topics: Animals; Antioxidants; B-Lymphocytes; Bronchoalveolar Lavage Fluid; Catechin; Female; Lymphocyte Subsets; Macrophages; Male; Mice; Mice, Inbred Strains; Neutrophils; Nicotiana; Pulmonary Emphysema; Respiratory Function Tests; Sex Factors; Smoke; T-Lymphocytes | 2006 |
Structure and intramolecular flexibility of beta-cyclodextrin complex with (-)-epigallocatechin gallate in aqueous solvent.
Topics: beta-Cyclodextrins; Catechin; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Solvents; Thermodynamics; Water | 2006 |
Interaction of (-)-epigallocatechin-3-gallate with human serum albumin: fluorescence, fourier transform infrared, circular dichroism, and docking studies.
Topics: Catechin; Circular Dichroism; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Serum Albumin; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Thermodynamics | 2006 |
Microarray-assisted pathway analysis identifies mitogen-activated protein kinase signaling as a mediator of resistance to the green tea polyphenol epigallocatechin 3-gallate in her-2/neu-overexpressing breast cancer cells.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Adhesion; Cell Growth Processes; Dexamethasone; Drug Resistance, Neoplasm; Enzyme Activation; Mammary Neoplasms, Experimental; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Oligonucleotide Array Sequence Analysis; Phosphorylation; Receptor, ErbB-2; RNA, Messenger | 2006 |
(-)-Epigallocatechin-3-gallate prevents photocarcinogenesis in mice through interleukin-12-dependent DNA repair.
Topics: Animals; Anticarcinogenic Agents; Catechin; DNA Repair; Female; Interleukin-12; Male; Mice; Mice, Inbred C3H; Mice, Knockout; Neoplasms, Radiation-Induced; Recombinant Proteins; Skin; Skin Neoplasms; Ultraviolet Rays; Xeroderma Pigmentosum Group A Protein | 2006 |
Inhibition of acid production in dental plaque bacteria by green tea catechins.
Topics: Acids; Adult; Anti-Bacterial Agents; Catechin; Dental Plaque; Female; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Streptococcus mutans; Tea | 2006 |
Green tea catechins inhibit pancreatic phospholipase A(2) and intestinal absorption of lipids in ovariectomized rats.
Topics: Animals; Camellia sinensis; Catechin; Female; Intestinal Absorption; Lipid Metabolism; Lymph Nodes; Ovariectomy; Ovary; Pancreas; Phospholipases A; Rats; Rats, Sprague-Dawley | 2006 |
Combined low dose ionizing radiation and green tea-derived epigallocatechin-3-gallate treatment induces human brain endothelial cells death.
Topics: Apoptosis; Brain; Camellia; Caspase 3; Catechin; Cell Cycle; Cell Death; Cell Line; Cell Survival; DNA Fragmentation; Endothelial Cells; Flow Cytometry; Humans; Immunoblotting; Necrosis; Photons | 2006 |
[Establishment of a novel molecular-targeted therapy for hematological malignancies mediated through reactive oxygen species (ROS)].
Topics: Antineoplastic Agents; Apoptosis; Capsaicin; Catechin; Homeostasis; Humans; Leukemia; Mitochondria; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species | 2006 |
Differential alterations in metabolic pattern of the spliceosomal UsnRNAs during pre-malignant lung lesions induced by benzo(a)pyrene: modulation by tea polyphenols.
Topics: Animals; Benzo(a)pyrene; Catechin; Flavonoids; Lung; Lung Neoplasms; Mice; Phenols; Polyphenols; Precancerous Conditions; RNA, Small Nuclear; Spliceosomes; Tea | 2006 |
Epigallocatechin gallate, the main ingredient of green tea induces apoptosis in breast cancer cells.
Topics: Anticarcinogenic Agents; Apoptosis; Breast Neoplasms; Caspase 3; Caspases; Catechin; Cell Cycle; Comet Assay; Flow Cytometry; Humans; Tumor Cells, Cultured | 2006 |
Effects of green tea on urinary stone formation: an in vivo and in vitro study.
Topics: Acetylglucosaminidase; Animals; Antioxidants; Catechin; Cell Line; Cell Survival; Cells, Cultured; Epithelium; Free Radicals; gamma-Glutamyltransferase; In Vitro Techniques; Kidney Calculi; Kidney Tubules, Proximal; Lipid Peroxidation; Male; Malondialdehyde; Oxalates; Rats; Rats, Sprague-Dawley; Tea | 2006 |
Green tea extract and (-)-epigallocatechin-3-gallate inhibit hypoxia- and serum-induced HIF-1alpha protein accumulation and VEGF expression in human cervical carcinoma and hepatoma cells.
Topics: Angiogenesis Inhibitors; Anticarcinogenic Agents; Carcinoma; Carcinoma, Hepatocellular; Catechin; Cell Hypoxia; Culture Media; Extracellular Signal-Regulated MAP Kinases; Female; HeLa Cells; Humans; Hypoxia-Inducible Factor 1; Liver Neoplasms; Phosphatidylinositol 3-Kinases; Plant Extracts; RNA, Messenger; Sirolimus; Uterine Cervical Neoplasms; Vascular Endothelial Growth Factor A | 2006 |
(-)-Epigallocatechin gallate regulates dopamine transporter internalization via protein kinase C-dependent pathway.
Topics: Animals; Catechin; Dopamine Plasma Membrane Transport Proteins; PC12 Cells; Protein Kinase C; Rats; RNA, Messenger; Signal Transduction | 2006 |
Antitumor effect of green tea polyphenol epigallocatechin-3-gallate in ovarian carcinoma cells: evidence for the endothelin-1 as a potential target.
Topics: Antineoplastic Agents; Catechin; Cell Line, Tumor; Cyclooxygenase Inhibitors; Dinoprostone; Endothelin A Receptor Antagonists; Endothelin-1; Female; Humans; Ovarian Neoplasms; Promoter Regions, Genetic; RNA, Messenger; Tea | 2006 |
The phyto-chemical (-)-epigallocatechin gallate suppresses gene expression of epidermal growth factor receptor in rat hepatic stellate cells in vitro by reducing the activity of Egr-1.
Topics: Animals; Base Sequence; Catechin; Cells, Cultured; DNA Primers; Early Growth Response Protein 1; Electrophoretic Mobility Shift Assay; ErbB Receptors; Gene Expression; Hepatocytes; Male; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Transcriptional Activation | 2006 |
Inhibition of proliferation and induction of apoptosis by EGCG in human osteogenic sarcoma (HOS) cells.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Catechin; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Osteosarcoma | 2006 |
Noncovalent cross-linking of casein by epigallocatechin gallate characterized by single molecule force microscopy.
Topics: Caseins; Catechin; Chemical Phenomena; Chemistry, Physical; Cross-Linking Reagents; Hydrophobic and Hydrophilic Interactions; Microscopy; Models, Molecular; Phosphorylation; Thermodynamics | 2006 |
Contribution of the 37-kDa laminin receptor precursor in the anti-metastatic PSP94-derived peptide PCK3145 cell surface binding.
Topics: Catechin; Cell Communication; Cell Line, Tumor; Collagen Type I; Drug Synergism; Humans; Kinetics; Matrix Metalloproteinase 9; Neoplasm Metastasis; Oligopeptides; Peptide Fragments; Prostatic Secretory Proteins; Protein Precursors; Receptors, Cell Surface; Receptors, Laminin | 2006 |
Sex- and strain-dependent effects of epigallocatechin gallate (EGCG) and epicatechin gallate (ECG) in the mouse.
Topics: Animals; Antioxidants; Aromatase; Catechin; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Injections, Intraperitoneal; Isoenzymes; Liver; Longevity; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Necrosis; Organ Size; Sex Factors; Species Specificity; Spleen | 2006 |
Effects of (-)-epigallocatechin-3-gallate on pancreatic beta-cell damage in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Catechin; Cell Count; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucose; Immunohistochemistry; Injections, Intraperitoneal; Insulin; Insulin-Secreting Cells; Male; Rats; Rats, Sprague-Dawley; Vitamin E; Vitamins | 2006 |
Epigallocathechin-3 gallate inhibits cardiac hypertrophy through blocking reactive oxidative species-dependent and -independent signal pathways.
Topics: Angiotensin II; Animals; Animals, Newborn; Antioxidants; Blotting, Northern; Blotting, Western; Cardiomegaly; Catechin; Electrophoretic Mobility Shift Assay; Enzyme Activation; ErbB Receptors; Hypertension; Male; MAP Kinase Kinase 4; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Transcription Factor AP-1 | 2006 |
Induction of CYP1A by green tea extract in human intestinal cell lines.
Topics: Caco-2 Cells; Catechin; Colon; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Phytotherapy; Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tea; Tumor Cells, Cultured | 2006 |
Apoptotic effect of EGCG in HT-29 colon cancer cells via AMPK signal pathway.
Topics: AMP-Activated Protein Kinase Kinases; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Catechin; Colonic Neoplasms; Cyclooxygenase 2; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Membrane Proteins; Protein Kinases; Pyrazoles; Pyrimidines; Reactive Oxygen Species; Signal Transduction | 2007 |
Bioassay-guided purification and identification of antimicrobial components in Chinese green tea extract.
Topics: Anti-Bacterial Agents; Bacteria; Beverages; Biological Assay; Catechin; Countercurrent Distribution; Drugs, Chinese Herbal; Flavonoids; Microbial Sensitivity Tests; Phenols; Polyphenols | 2006 |
Iron-chelating and free-radical scavenging activities of microwave-processed green tea in iron overload.
Topics: Antioxidants; beta-Thalassemia; Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Desiccation; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Erythrocytes; Ferric Compounds; Free Radical Scavengers; Hot Temperature; Humans; In Vitro Techniques; Iron; Iron Chelating Agents; Iron Overload; Kinetics; Lipid Peroxidation; Microwaves; Nitrates; Oxidative Stress; Plant Extracts; Plasma; Tea | 2006 |
[Halitosis and polyphenols].
Topics: Antioxidants; Catechin; Flavonoids; Halitosis; Humans; Phenols; Polyphenols; Sulfur Compounds; Taste Disorders; Tea | 2006 |
Can green tea protect against not only sunburn but also melanoma?
Topics: Catechin; Melanoma; Nitric Oxide; Skin Neoplasms; Sunburn; Tea; Ultraviolet Rays | 2006 |
Green tea flavonols inhibit glucosidase II.
Topics: alpha-Glucosidases; Animals; Catechin; Chromatography, High Pressure Liquid; Flavonols; Glycoside Hydrolase Inhibitors; Kinetics; Male; Microsomes, Liver; Rats; Rats, Wistar; Tea | 2006 |
Specific killing of multiple myeloma cells by (-)-epigallocatechin-3-gallate extracted from green tea: biologic activity and therapeutic implications.
Topics: Animals; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Gene Expression Profiling; Humans; Mice; Mice, SCID; Multiple Myeloma; Neoplasm Transplantation; Phytotherapy; Receptors, Laminin; RNA, Small Interfering; Tea; Transplantation, Heterologous | 2006 |
Comparison of potential chemotherapeutic agents, 5-fluoruracil, green tea, and thymoquinone on colon cancer cells.
Topics: Antineoplastic Agents; Benzoquinones; Catechin; Cell Proliferation; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Feasibility Studies; Fluorouracil; Plant Extracts; Tea; Treatment Outcome | 2006 |
The physiological effect of conventional treatment with epigallocatechin-3-gallate, thymoquinone, and tannic acid on the LNCaP cell line.
Topics: Antineoplastic Agents; Antioxidants; Benzoquinones; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Humans; Male; Prostatic Neoplasms; Tannins; Treatment Outcome | 2006 |
Effects of (-)epigallocatechin gallate and thymoquinone on proliferation of a PANC-1 cell line in culture.
Topics: Adenocarcinoma; Antineoplastic Agents; Antioxidants; Benzoquinones; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Humans; Pancreatic Neoplasms; Treatment Outcome | 2006 |
Green tea polyphenol epigallocatechin-3-gallate inhibits the endothelin axis and downstream signaling pathways in ovarian carcinoma.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; bcl-X Protein; Caspase 3; Caspases; Catechin; Cell Proliferation; Endothelin-1; Enzyme Activation; Female; Humans; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Ovarian Neoplasms; Phosphatidylinositol 3-Kinases; Receptor, Endothelin A; Signal Transduction; Tea; Transplantation, Heterologous; Urokinase-Type Plasminogen Activator; Vascular Endothelial Growth Factor A | 2006 |
The effects of (-)-epigallocatechin-3-gallate on the proliferation and differentiation of human megakaryocytic progenitor cells.
Topics: Catechin; Cell Differentiation; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; Megakaryocytes; Radiation Dosage; Radiation-Protective Agents; Stem Cells | 2006 |
Antifungal susceptibility of epigallocatechin 3-O-gallate (EGCg) on clinical isolates of pathogenic yeasts.
Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis; Catechin; Dose-Response Relationship, Drug; Echinocandins; Fluconazole; Flucytosine; Humans; Itraconazole; Lipopeptides; Lipoproteins; Micafungin; Miconazole; Microbial Sensitivity Tests; Peptides, Cyclic; Species Specificity | 2006 |
Therapeutic potential of (-)-epigallocatechin 3-O-gallate on renal damage in diabetic nephropathy model rats.
Topics: Animals; Body Weight; Catechin; Cyclooxygenase 2; Diabetic Nephropathies; Fibronectins; Kidney; Male; NF-kappa B; Nitric Oxide Synthase Type II; Organ Size; Proteinuria; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Transforming Growth Factor beta | 2006 |
Green tea extract and (-)-epigallocatechin-3-gallate inhibit mast cell-stimulated type I collagen expression in keloid fibroblasts via blocking PI-3K/AkT signaling pathways.
Topics: Camellia sinensis; Catechin; Cells, Cultured; Coculture Techniques; Collagen Type I; Fibroblasts; Humans; Keloid; Mast Cells; Phosphatidylinositol 3-Kinases; Plant Extracts; Proto-Oncogene Proteins c-akt; Signal Transduction | 2006 |
Anxiolytic properties of green tea polyphenol (-)-epigallocatechin gallate (EGCG).
Topics: Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Behavior, Animal; Carbolines; Catechin; Cells, Cultured; Chlordiazepoxide; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Electroshock; Embryo, Mammalian; gamma-Aminobutyric Acid; Hippocampus; Male; Maze Learning; Membrane Potentials; Mice; Neurons; Patch-Clamp Techniques; Reaction Time | 2006 |
Effects of a natural extract from Mangifera indica L, and its active compound, mangiferin, on energy state and lipid peroxidation of red blood cells.
Topics: Ascorbic Acid; Catechin; Chromatography, High Pressure Liquid; Erythrocytes; Hemolysis; Humans; Hydrogen Peroxide; Lipid Peroxidation; Malondialdehyde; Mangifera; Plant Extracts; Xanthones | 2006 |
Green tea polyphenol EGCG suppresses cigarette smoke condensate-induced NF-kappaB activation in normal human bronchial epithelial cells.
Topics: Anticarcinogenic Agents; Antioxidants; Apoptosis; Bronchi; Catechin; Cyclin D1; Cyclooxygenase 2; DNA; Epithelial Cells; Humans; Matrix Metalloproteinase 9; Membrane Proteins; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphorylation; Signal Transduction; Smoke; Tea; Vascular Endothelial Growth Factor A | 2007 |
Regulation of interleukin-1beta-induced chemokine production and matrix metalloproteinase 2 activation by epigallocatechin-3-gallate in rheumatoid arthritis synovial fibroblasts.
Topics: Arthritis, Rheumatoid; Catechin; Cell Survival; Cells, Cultured; Chemokines; Culture Media, Conditioned; Dose-Response Relationship, Drug; Down-Regulation; Drug Combinations; Fibroblasts; Humans; Interleukin-1; Matrix Metalloproteinase 3; Synovial Membrane | 2006 |
Yeast-based assay for the measurement of positive and negative influences on microsatellite stability.
Topics: Blotting, Western; Catechin; DNA Replication; Genomic Instability; Hydroxyurea; Microsatellite Repeats; Saccharomyces cerevisiae; Tea | 2006 |
Kinetic study of the thermal stability of tea catechins in aqueous systems using a microwave reactor.
Topics: Catechin; Drug Stability; Hot Temperature; Kinetics; Microwaves; Solutions; Tea; Thermodynamics; Water | 2006 |
Copper complexes of (-)-epicatechin gallate and (-)-epigallocatechin gallate act as inhibitors of Ribonuclease A.
Topics: Catechin; Circular Dichroism; Copper; Enzyme Inhibitors; Kinetics; Ribonuclease, Pancreatic; Spectroscopy, Fourier Transform Infrared | 2006 |
The involvement of the 67 kDa laminin receptor-mediated modulation of cytoskeleton in the degranulation inhibition induced by epigallocatechin-3-O-gallate.
Topics: Basophils; Calcimycin; Catechin; Cell Degranulation; Cell Line, Tumor; Cytoskeleton; Histamine Release; Humans; Membrane Microdomains; Myosin Light Chains; Myosin Type II; Phosphorylation; Receptors, Laminin | 2006 |
Suppression of MyD88- and TRIF-dependent signaling pathways of Toll-like receptor by (-)-epigallocatechin-3-gallate, a polyphenol component of green tea.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Catechin; Cell Line; Cyclooxygenase 2; Flavonoids; Gene Expression; Humans; I-kappa B Kinase; Interferon-gamma; Luciferases; Mice; Myeloid Differentiation Factor 88; NF-kappa B; NF-kappaB-Inducing Kinase; Phenols; Polyphenols; Protein Serine-Threonine Kinases; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tea; Toll-Like Receptor 2; Toll-Like Receptor 4; Toll-Like Receptors; Transfection | 2006 |
Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models.
Topics: Animals; Animals, Genetically Modified; Camellia sinensis; Catechin; Drosophila melanogaster; Exons; Humans; Huntingtin Protein; Huntington Disease; In Vitro Techniques; Microscopy, Atomic Force; Models, Biological; Motor Neurons; Multiprotein Complexes; Mutation; Nerve Degeneration; Nerve Tissue Proteins; Nuclear Proteins; Photoreceptor Cells, Invertebrate; Phytotherapy; Protein Conformation; Protein Folding; Protein Structure, Quaternary; Recombinant Fusion Proteins; Saccharomyces cerevisiae | 2006 |
Epigallocatechin gallate preserves endothelial function by reducing the endogenous nitric oxide synthase inhibitor level.
Topics: Animals; Arginine; Catechin; Cells, Cultured; Cholesterol, LDL; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Male; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Vasodilation | 2006 |
(-)-Epigallocatechin-3-gallate protects mice from concanavalin A-induced hepatitis through suppressing immune-mediated liver injury.
Topics: Alanine Transaminase; Animals; Apoptosis; Catechin; Chemical and Drug Induced Liver Injury; Chemokine CCL4; Chemokine CXCL10; Chemokines, CXC; Concanavalin A; Hepatocytes; Immunohistochemistry; Interferon-gamma; Liver; Macrophage Inflammatory Proteins; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Nitrites; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 2006 |
Comparative efficacy of oligonol, catechin and (-)-epigallocatechin 3-O-gallate in modulating the potassium bromate-induced renal toxicity in rats.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; Bromates; Catechin; Creatinine; Flavonoids; Kidney Diseases; Kidney Function Tests; Lipid Peroxidation; Male; Phenols; Pinus; Polyphenols; Rats; Rats, Wistar; Seeds; Vitis | 2006 |
Epigallocatechin gallate (EGCG) mimics insulin action on the transcription factor FOXO1a and elicits cellular responses in the presence and absence of insulin.
Topics: Catechin; Cell Line; Drug Interactions; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Insulin; Molecular Structure; Phosphatidylinositol 3-Kinases; Phosphoenolpyruvate Carboxykinase (ATP); Phosphorylation; Promoter Regions, Genetic; Reactive Oxygen Species; Signal Transduction; Transcription Factors; Transfection | 2007 |
Constitutive overexpression of Nrf2-dependent heme oxygenase-1 in A549 cells contributes to resistance to apoptosis induced by epigallocatechin 3-gallate.
Topics: Adenocarcinoma; Antioxidants; Apoptosis; Catechin; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Heme Oxygenase-1; Humans; Lung Neoplasms; NF-E2-Related Factor 2; Oxidation-Reduction; Protein Kinase C-alpha; Response Elements; RNA, Small Interfering; Sensitivity and Specificity; Transcriptional Activation | 2006 |
Iron chelators reduce chromosomal breaks in ataxia-telangiectasia cells.
Topics: Antibodies; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Catechin; Cell Culture Techniques; Cell Cycle Proteins; Cell Line; Chromosome Breakage; Deferoxamine; DNA-Binding Proteins; Drug Synergism; Humans; Iron; Iron Chelating Agents; Mutagens; Organometallic Compounds; Protein Serine-Threonine Kinases; Receptors, Transferrin; Recombinant Fusion Proteins; Salicylates; tert-Butylhydroperoxide; Thioctic Acid; Tumor Suppressor Proteins | 2006 |
Uptake and distribution of catechins in fetal organs following in utero exposure in rats.
Topics: Animals; Brain; Camellia sinensis; Catechin; Eye; Female; Fetal Heart; Fetus; Kidney; Liver; Lung; Maternal-Fetal Exchange; Plant Extracts; Pregnancy; Rats; Tissue Distribution | 2007 |
Epigallocatechin-3-gallate increases the formation of mineralized bone nodules by human osteoblast-like cells.
Topics: Alkaline Phosphatase; Calcification, Physiologic; Catechin; Cell Differentiation; Cells, Cultured; Core Binding Factor Alpha 1 Subunit; Dose-Response Relationship, Drug; Humans; Osteoblasts | 2007 |
Methylation of green tea polyphenols affects their binding to and inhibitory poses of the proteasome beta5 subunit.
Topics: Catechin; Chymotrypsin; Dose-Response Relationship, Drug; Flavonoids; Methylation; Models, Molecular; Molecular Conformation; Phenols; Polyphenols; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Protein Subunits; Tea | 2006 |
Impact of quercetin and EGCG on key elements of the Wnt pathway in human colon carcinoma cells.
Topics: beta Catenin; Catechin; Cell Division; Colonic Neoplasms; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Homeostasis; HT29 Cells; Humans; Quercetin; Wnt Proteins | 2006 |
Polyphenol (-)-epigallocatechin gallate protection from ischemia/reperfusion-induced renal injury in normotensive and hypertensive rats.
Topics: Animals; Blood Urea Nitrogen; Catechin; Creatinine; Disease Models, Animal; Flavonoids; Hypertension; Phenols; Polyphenols; Rats; Rats, Inbred SHR; Reference Values; Renal Circulation; Reperfusion Injury | 2006 |
(-)-Epigallocatechin gallate overcomes resistance to etoposide-induced cell death by targeting the molecular chaperone glucose-regulated protein 78.
Topics: Adenosine Triphosphatases; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Caspase 7; Caspase Inhibitors; Catechin; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Etoposide; Heat-Shock Proteins; Humans; Mice; Molecular Chaperones; Protein Conformation; Urinary Bladder Neoplasms | 2006 |
Epigallocatechin gallate supplementation alleviates diabetes in rodents.
Topics: Acyl-CoA Oxidase; Adipose Tissue; Animals; Blood Glucose; Carnitine O-Palmitoyltransferase; Catechin; Cell Line, Tumor; Diabetes Mellitus, Type 2; Dietary Supplements; Gene Expression; Gene Expression Regulation; Glucokinase; Glucose; Glucose Tolerance Test; Lipid Metabolism; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Sprague-Dawley; RNA, Messenger | 2006 |
Dietary factors may modify cancer risk by altering xenobiotic metabolism and many other mechanisms.
Topics: Animals; Catechin; Cells, Cultured; Diet; Humans; Neoplasms; Risk Factors; Xenobiotics | 2006 |
Peracetylation as a means of enhancing in vitro bioactivity and bioavailability of epigallocatechin-3-gallate.
Topics: Acetates; Acetylation; Animals; Anticarcinogenic Agents; Arachidonic Acid; Biological Availability; Catechin; Cell Line, Tumor; Cell Proliferation; Colon; Esterases; Humans; Intestine, Small; Male; Mice; Mice, Inbred Strains; Nitric Oxide | 2006 |
EGCG protects HT-22 cells against glutamate-induced oxidative stress.
Topics: Animals; Antioxidants; Catechin; Cell Line, Transformed; Cell Survival; Coculture Techniques; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Glutamic Acid; Heme Oxygenase-1; Hippocampus; Mice; Oxidative Stress; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2006 |
Kinetic properties of a MNB/DYRK1A mutant suitable for the elucidation of biochemical pathways.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Animals; Antioxidants; Catechin; Down Syndrome; Drug Resistance; Dyrk Kinases; Kinetics; Mice; Mutation, Missense; NIH 3T3 Cells; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases | 2006 |
A water extract of Artemisia capillaris prevents 2,2'-azobis(2-amidinopropane) dihydrochloride-induced liver damage in rats.
Topics: Alanine Transaminase; Amidines; Animals; Artemisia; Aspartate Aminotransferases; Catechin; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Liver; Liver Diseases; Male; Oxidants; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Water | 2006 |
Functional characterization of AATF transcriptome in human leukemic cells.
Topics: Androstadienes; Apoptosis; Apoptosis Regulatory Proteins; Base Sequence; Catechin; Cell Survival; Flow Cytometry; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Jurkat Cells; Leukemia; Models, Biological; Molecular Sequence Data; Proto-Oncogene Proteins c-myc; Repressor Proteins; Response Elements; Sp1 Transcription Factor; Transcription Factors; Transcription, Genetic; Wortmannin | 2007 |
Assessment of the polyphenolic composition of the organic extracts of Mauritian black teas: a potential contributor to their antioxidant functions.
Topics: Antioxidants; Catechin; Chromatography, High Pressure Liquid; Flavonoids; Flavonols; Gallic Acid; Oxidation-Reduction; Phenols; Plant Extracts; Polyphenols; Proanthocyanidins; Tea | 2006 |
Involvement of early growth response gene 1 in the modulation of microsomal prostaglandin E synthase 1 by epigallocatechin gallate in A549 human pulmonary epithelial cells.
Topics: Base Sequence; Catechin; Cell Line; DNA Primers; Early Growth Response Protein 1; Epithelial Cells; Humans; Intramolecular Oxidoreductases; Lung; Microscopy, Confocal; Microsomes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Promoter Regions, Genetic; Prostaglandin-E Synthases; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
Pro-oxidative effects of tea and polyphenols, epigallocatechin-3-gallate and epigallocatechin, on G6PD-deficient erythrocytes in vitro.
Topics: Adult; Camellia sinensis; Catechin; Erythrocytes; Flavonoids; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Deficiency; Glutathione; Glutathione Disulfide; Humans; Male; Mutation; Oxidants; Phenols; Polyphenols; Tea | 2006 |
Epigallocatechin-3-gallate inhibits the PDGF-induced VEGF expression in human vascular smooth muscle cells via blocking PDGF receptor and Erk-1/2.
Topics: Angiogenesis Inhibitors; Anticarcinogenic Agents; Catechin; Cell Proliferation; Culture Media, Conditioned; Endothelial Cells; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Receptors, Platelet-Derived Growth Factor; Umbilical Cord; Vascular Endothelial Growth Factor A | 2006 |
Electrochemical studies of (-)-epigallocatechin gallate and its interaction with DNA.
Topics: Catechin; DNA; Electrochemistry; Molecular Structure | 2006 |
Neuroprotective effects of (-)-epigallocatechin-3-gallate in a transgenic mouse model of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Blotting, Western; Caspase 3; Catechin; Disease Models, Animal; Enzyme Activation; Female; Immunohistochemistry; Male; Mice; Mice, Transgenic; Microglia; Motor Neurons; Neuroprotective Agents; NF-kappa B | 2006 |
Plant phenolics inhibit neutrophil elastase.
Topics: Catechin; Genistein; Humans; Hydrolyzable Tannins; Leukocyte Elastase; Phenols; Phenylethyl Alcohol; Plant Extracts; Proteinase Inhibitory Proteins, Secretory; Resveratrol; Stilbenes | 2006 |
(--)-epigallocatechin gallate enhances prostaglandin F2alpha-induced VEGF synthesis via upregulating SAPK/JNK activation in osteoblasts.
Topics: Animals; Animals, Newborn; Antioxidants; Catechin; Cell Line; Dinoprost; Enzyme Activation; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; Osteoblasts; Oxytocics; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protease Inhibitors; Proto-Oncogene Proteins c-jun; Signal Transduction; Up-Regulation; Vascular Endothelial Growth Factor A | 2007 |
Identification of two biologically crucial hydroxyl groups of (-)-epigallocatechin gallate in osteoclast culture.
Topics: Animals; Animals, Newborn; Catechin; Cell Death; Cells, Cultured; Hydrogen Peroxide; Hydrogen-Ion Concentration; Iron; Male; Mice; Osteoblasts; Oxidation-Reduction | 2007 |
Epigallocatechin gallate induced apoptosis in Sarcoma180 cells in vivo: mediated by p53 pathway and inhibition in U1B, U4-U6 UsnRNAs expression.
Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Catechin; Cell Cycle; Cell Proliferation; Gene Expression Regulation, Neoplastic; In Situ Nick-End Labeling; Injections, Intraperitoneal; Mice; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; RNA, Messenger; RNA, Neoplasm; RNA, Small Nuclear; Sarcoma; Tumor Suppressor Protein p53 | 2006 |
Effects of interactions of EGCG and Cd(2+) on the growth of PC-3 cells and their mechanisms.
Topics: Absorption; Animals; Anticarcinogenic Agents; Cadmium; Catechin; Cell Division; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Humans; Male; Prostatic Neoplasms; Spectrophotometry, Atomic; Spectrophotometry, Ultraviolet; Tea; Tetrazolium Salts; Thiazoles; Time Factors; Zinc | 2007 |
Mixed-mode retention mechanism for (-)-epigallocatechin gallate on a 12% cross-linked agarose gel media.
Topics: Acetonitriles; Adsorption; Alcohols; Catechin; Chromatography, Agarose; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Sepharose; Solvents; Tea | 2006 |
Epigallocatechin gallate and caffeine differentially inhibit the intestinal absorption of cholesterol and fat in ovariectomized rats.
Topics: Animals; Caffeine; Catechin; Cholesterol; Fatty Acids; Female; Intestinal Absorption; Lymph; Ovariectomy; Phospholipids; Rats; Rats, Sprague-Dawley | 2006 |
Positive inotropic effect of purified green tea catechin derivative in guinea pig hearts: the measurements of cellular Ca2+ and nitric oxide release.
Topics: Animals; Blood Pressure; Calcium; Cardiotonic Agents; Catechin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Perfusion; Pyridazines; Rabbits; Signal Transduction; Tea; Vasodilator Agents; Ventricular Function; Ventricular Pressure | 2006 |
Uniformly-sized, molecularly imprinted polymers for (-)-epigallocatechin gallate, -epicatechin gallate and -gallocatechin gallate by multi-step swelling and polymerization method.
Topics: Catechin; Chromatography, High Pressure Liquid; Tea | 2007 |
EGCG mitigates neurotoxicity mediated by HIV-1 proteins gp120 and Tat in the presence of IFN-gamma: role of JAK/STAT1 signaling and implications for HIV-associated dementia.
Topics: AIDS Dementia Complex; Analysis of Variance; Animals; Apoptosis; Catechin; Cells, Cultured; Female; Gene Products, tat; HIV Envelope Protein gp120; HIV-1; Interferon-gamma; Janus Kinases; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Neuroprotective Agents; Neurotoxins; Signal Transduction; STAT1 Transcription Factor; tat Gene Products, Human Immunodeficiency Virus | 2006 |
Catechins inhibit angiotensin II-induced vascular smooth muscle cell proliferation via mitogen-activated protein kinase pathway.
Topics: Angiotensin II; Animals; Catechin; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; DNA; Female; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction | 2006 |
Effect of epigallocatechingallate on ultraviolet B-induced photo-damage in keratinocyte cell line.
Topics: Apoptosis; Catechin; Cell Line; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression; Humans; Interleukin-6; Keratinocytes; Proto-Oncogene Proteins c-fos; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Ultraviolet Rays | 2006 |
Inhibition of HuR and MMP-9 expression in macrophage-differentiated HL-60 myeloid leukemia cells by green tea polyphenol EGCg.
Topics: Anticarcinogenic Agents; Antigens, Surface; Carcinogens; Catechin; Cell Adhesion; Cell Differentiation; ELAV Proteins; ELAV-Like Protein 1; HL-60 Cells; Humans; Immunoblotting; Macrophages; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; RNA-Binding Proteins; Tea; Tetradecanoylphorbol Acetate | 2007 |
Oxidative-induced retinal degeneration is attenuated by epigallocatechin gallate.
Topics: Animals; Brain; Caspase 3; Catechin; Choline O-Acetyltransferase; Electroretinography; gamma-Aminobutyric Acid; Gene Expression Regulation; Immunohistochemistry; In Situ Nick-End Labeling; Lipid Peroxidation; Neurofilament Proteins; Neuroprotective Agents; Oxidative Stress; Protein Kinase C; Rats; Retinal Degeneration; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rod Opsins; Sensory Rhodopsins; Thy-1 Antigens | 2006 |
Epigallocatechin gallate and genistein attenuate glial fibrillary acidic protein elevation induced by fibrogenic cytokines in hepatic stellate cells.
Topics: Animals; Blotting, Western; Catechin; Cell Line; Cytokines; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Genistein; Glial Fibrillary Acidic Protein; Hepatocytes; Molecular Structure; Rats; RNA, Messenger; Time Factors; Transfection; Transgenes | 2006 |
[Comparative characteristics of the antioxidants of plant origin introduced in fat emulsion foods].
Topics: alpha-Tocopherol; Antioxidants; Ascorbic Acid; Butylated Hydroxyanisole; Catechin; Cinnamates; Depsides; Dietary Fats; Emulsions; Food Preservation; Plants; Rosmarinic Acid; Soybean Oil | 2006 |
The reduction of hypoxia-induced and reoxygenation-induced apoptosis in rat islets by epigallocatechin gallate.
Topics: Animals; Apoptosis; Catechin; Cell Hypoxia; Islets of Langerhans; Islets of Langerhans Transplantation; L-Lactate Dehydrogenase; Oxygen Consumption; Rats; Rats, Inbred F344 | 2006 |
Trapping reactions of reactive carbonyl species with tea polyphenols in simulated physiological conditions.
Topics: Acetylation; Biflavonoids; Catechin; Chromatography, Gas; Chromatography, High Pressure Liquid; Flavonoids; Glycation End Products, Advanced; Glyoxal; Kinetics; Magnetic Resonance Spectroscopy; Phenols; Polyphenols; Pyruvaldehyde; Spectrometry, Mass, Electrospray Ionization; Tea | 2006 |
Effects of green tea compounds on irinotecan metabolism.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Catechin; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Glucuronates; Glucuronosyltransferase; Hepatocytes; Humans; Hydroxytestosterones; Irinotecan; RNA, Messenger; Tea | 2007 |
Green tea polyphenol epigallocatechin-3-gallate suppresses rat hepatic stellate cell invasion by inhibition of MMP-2 expression and its activation.
Topics: Animals; Catechin; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Gene Expression; Liver; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Rats; RNA, Messenger; Tea | 2006 |
Mouse embryonic fibroblast cells from transgenic mice overexpressing tNOX exhibit an altered growth and drug response phenotype.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Shape; Cells, Cultured; Embryo, Mammalian; Female; Fibroblasts; Isoflavones; Male; Mice; Mice, Transgenic; NADH, NADPH Oxidoreductases; Neoplasms; Oxidation-Reduction; Phenotype | 2007 |
Epigallocatechin gallate inhibits nitric oxide-induced apoptosis in rat PC12 cells.
Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspases; Catechin; Cytochromes c; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Time Factors; Voltage-Dependent Anion Channels | 2007 |
Green tea polyphenols function as prooxidants to activate oxidative-stress-responsive transcription factors in yeasts.
Topics: Camellia sinensis; Catechin; Cell Nucleus; Flavonoids; Heat-Shock Response; Hydrogen Peroxide; Membrane Proteins; Oxidative Stress; Pancreatitis-Associated Proteins; Phenols; Plant Extracts; Polyphenols; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Thioredoxins; Transcription Factors; Transcriptional Activation | 2007 |
Epigallocatechin-3-gallate inhibits secretion of TNF-alpha, IL-6 and IL-8 through the attenuation of ERK and NF-kappaB in HMC-1 cells.
Topics: Calcimycin; Calcium; Catechin; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Humans; Interleukin-6; Interleukin-8; Ionophores; NF-kappa B; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2007 |
Epigallocatechin gallate's protective effect against MMP7 in recessive dystrophic epidermolysis bullosa patients.
Topics: Adult; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Blotting, Western; Catechin; Collagen Type VII; Elastic Tissue; Epidermolysis Bullosa Dystrophica; Fibrillin-1; Fibrillins; Genes, Recessive; Humans; Immunologic Techniques; Matrix Metalloproteinase 7; Matrix Metalloproteinase Inhibitors; Microfilament Proteins; Organ Culture Techniques; Protease Inhibitors; Skin; Staining and Labeling; Time Factors; Tissue Distribution | 2007 |
Electron-impact and glow-discharge ionization LC-MS analysis of green tea tincture.
Topics: Caffeine; Camellia sinensis; Catechin; Chromatography, Liquid; Dietary Supplements; Mass Spectrometry; Molecular Structure; Plant Extracts; Plant Leaves; Tea | 2007 |
Green tea polyphenol (-) -epigallocatechin-3-gallate promotes the rapid protein kinase C- and proteasome-mediated degradation of Bad: implications for neuroprotection.
Topics: bcl-Associated Death Protein; Blotting, Western; Catechin; Cell Line, Tumor; Cell Survival; Chymotrypsin; Drug Interactions; Enzyme Inhibitors; Gene Expression Regulation; Humans; Models, Biological; Neuroblastoma; Neuroprotective Agents; Proteasome Endopeptidase Complex; Protein Kinase C; Time Factors; Transfection | 2007 |
Beneficial effects of natural antioxidants EGCG and alpha-lipoic acid on life span and age-dependent behavioral declines in Caenorhabditis elegans.
Topics: Aging; Amyloid beta-Peptides; Animals; Antioxidants; Caenorhabditis elegans; Catechin; Chemotaxis; Hydrogen Peroxide; Life Expectancy; Pharynx; Thioctic Acid | 2006 |
Epigallocatechin gallate, the main polyphenol in green tea, binds to the T-cell receptor, CD4: Potential for HIV-1 therapy.
Topics: Binding Sites; Catechin; CD4 Antigens; CD4 Immunoadhesins; Flavonoids; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Phenols; Polyphenols; Protease Inhibitors; Receptors, HIV; Tea | 2006 |
Inactivation mechanism of the beta-ketoacyl-[acyl carrier protein] reductase of bacterial type-II fatty acid synthase by epigallocatechin gallate.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Acetyltransferases; Alcohol Oxidoreductases; Bacterial Proteins; Catechin; Chemical Precipitation; Fatty Acid Synthase, Type II; Fatty Acid Synthases; Models, Biological; Multienzyme Complexes; Protease Inhibitors; Protein Binding; Time Factors | 2006 |
Antimalarial properties of green tea.
Topics: Animals; Antimalarials; Catechin; Dose-Response Relationship, Drug; Plant Extracts; Plasmodium falciparum; Tea | 2007 |
Effects of (-)-epigallocatechin-3-gallate on the activity of substantia nigra dopaminergic neurons.
Topics: Animals; Antioxidants; Catechin; Dopamine; Immunohistochemistry; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Substantia Nigra | 2007 |
Protective effects of EGCg or GCg, a green tea catechin epimer, against postischemic myocardial dysfunction in guinea-pig hearts.
Topics: Animals; Antioxidants; Apoptosis; Calcium; Caspase 3; Catechin; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Female; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Male; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocardium; Perfusion; Reactive Oxygen Species | 2007 |
Dietary polyphenols may affect DNA methylation.
Topics: Adaptor Proteins, Signal Transducing; Animals; Carrier Proteins; Catechin; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cyclin-Dependent Kinase Inhibitor p16; Diet; DNA Methylation; DNA Modification Methylases; Flavonoids; Genistein; Homocysteine; Humans; Mice; MutL Protein Homolog 1; Nuclear Proteins; Phenols; Polyphenols; Promoter Regions, Genetic; Receptors, Retinoic Acid; S-Adenosylmethionine; Tumor Suppressor Protein p14ARF | 2007 |
Antidiabetic activity of lipophilic (-)-epigallocatechin-3-gallate derivative under its role of alpha-glucosidase inhibition.
Topics: Animals; Antioxidants; Body Weight; Catechin; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Lipids; Male; Rats; Rats, Sprague-Dawley | 2007 |
EGCG-targeted p57/KIP2 reduces tumorigenicity of oral carcinoma cells: role of c-Jun N-terminal kinase.
Topics: Animals; Anthracenes; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Catechin; Cell Line; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p57; Cytochromes c; Disease-Free Survival; Enzyme Inhibitors; Female; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Nude; Mouth Neoplasms; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Signal Transduction; Transfection; Xenograft Model Antitumor Assays | 2007 |
Role of green tea polyphenols in the inhibition of collagenolytic activity by collagenase.
Topics: Animals; Catechin; Circular Dichroism; Collagen; Enzyme Inhibitors; Flavonoids; In Vitro Techniques; Kinetics; Male; Matrix Metalloproteinase Inhibitors; Models, Molecular; Phenols; Polyphenols; Protein Conformation; Rats; Rats, Wistar; Tea | 2007 |
Modulation of pregnane X receptor- and electrophile responsive element-mediated gene expression by dietary polyphenolic compounds.
Topics: Catechin; Cell Line, Tumor; Curcumin; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dietary Supplements; Flavonoids; Gene Expression Regulation; Glutathione Peroxidase; Heme Oxygenase-1; Humans; Phenols; Plant Extracts; Polyphenols; Pregnane X Receptor; Promoter Regions, Genetic; Quercetin; Receptors, Steroid; Response Elements; Resveratrol; Stilbenes; Syzygium; Thymus Plant | 2007 |
Evidence of a novel antiapoptotic factor: role of inhibitor of differentiation or DNA binding (Id-1) in anticancer drug-induced apoptosis.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Survival; Cisplatin; Down-Regulation; Doxorubicin; Etoposide; Female; HeLa Cells; Humans; Inhibitor of Differentiation Protein 1; Liver Neoplasms; Male; Mechlorethamine; Methotrexate; Mitomycin; Nasopharyngeal Neoplasms; Paclitaxel; Prostatic Neoplasms; Vincristine | 2007 |
[Green tea for reduction of plaque development].
Topics: Catechin; Humans; Huntington Disease; Neuroprotective Agents; Tea | 2006 |
Food components inhibiting recombinant human histidine decarboxylase activity.
Topics: Catechin; Enzyme Inhibitors; Food; Food Analysis; Histamine; Histidine; Histidine Decarboxylase; Humans; Kinetics; Recombinant Proteins | 2007 |
EGCG, a green tea polyphenol, improves endothelial function and insulin sensitivity, reduces blood pressure, and protects against myocardial I/R injury in SHR.
Topics: Animals; Blood Pressure; Catechin; Enalapril; Endothelium, Vascular; In Vitro Techniques; Insulin Resistance; Male; Mesenteric Veins; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WF; Tea; Vasodilator Agents | 2007 |
Green tea catechins inhibit bacterial DNA gyrase by interaction with its ATP binding site.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Anti-Bacterial Agents; Binding Sites; Catechin; DNA Gyrase; Escherichia coli; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Models, Molecular; Structure-Activity Relationship; Tea; Topoisomerase II Inhibitors | 2007 |
Epigallocatechin-3-gallate enhances CD8+ T cell-mediated antitumor immunity induced by DNA vaccination.
Topics: Animals; Antigens, Neoplasm; Apoptosis; Catechin; CD8-Positive T-Lymphocytes; Combined Modality Therapy; Dendritic Cells; Female; Human papillomavirus 16; Lymph Nodes; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Th1 Cells; Vaccines, DNA | 2007 |
Inhibition by epigallocatechin gallate of CoCl2-induced apoptosis in rat PC12 cells.
Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Caspase 9; Catechin; Cell Differentiation; Cobalt; DNA Fragmentation; Electrophoresis, Agar Gel; Flow Cytometry; Genes, bcl-2; Hypoxia-Ischemia, Brain; Membrane Potentials; Mitochondrial Membranes; Neuroprotective Agents; PC12 Cells; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2007 |
EGCG inhibits cardiomyocyte apoptosis in pressure overload-induced cardiac hypertrophy and protects cardiomyocytes from oxidative stress in rats.
Topics: Animals; Apoptosis; Blood Pressure; Cardiomegaly; Catechin; Cell Survival; L-Lactate Dehydrogenase; Male; Malondialdehyde; Myocytes, Cardiac; Organ Size; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53 | 2007 |
Pharmacokinetics of (-)-epigallocatechin-3-gallate in conscious and freely moving rats and its brain regional distribution.
Topics: Animals; Blood Proteins; Brain Chemistry; Camellia sinensis; Catechin; Male; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2007 |
The kinetics and mechanisms of the complex formation and antioxidant behaviour of the polyphenols EGCg and ECG with iron(III).
Topics: Antioxidants; Catechin; Ferric Compounds; Kinetics; Molecular Structure; Spectrophotometry, Ultraviolet; Temperature | 2007 |
Green tea catechins potentiate triclosan binding to enoyl-ACP reductase from Plasmodium falciparum (PfENR).
Topics: Animals; Antimalarials; Catechin; Chalcones; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Escherichia coli; Kinetics; Models, Molecular; Plasmodium falciparum; Protein Binding; Quercetin; Tea; Triclosan | 2007 |
A component of green tea, (-)-epigallocatechin-3-gallate, promotes apoptosis in T24 human bladder cancer cells via modulation of the PI3K/Akt pathway and Bcl-2 family proteins.
Topics: Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Urinary Bladder Neoplasms | 2007 |
Transdermal delivery of tea catechins and theophylline enhanced by terpenes: a mechanistic study.
Topics: Administration, Cutaneous; Animals; Catechin; Female; In Vitro Techniques; Rats; Rats, Wistar; Skin; Skin Absorption; Terpenes; Theophylline; Water | 2007 |
(-)-Epigallocatechin gallate suppresses indoleamine 2,3-dioxygenase expression in murine dendritic cells: evidences for the COX-2 and STAT1 as potential targets.
Topics: Animals; Catechin; Cyclooxygenase 2; Dendritic Cells; Down-Regulation; Enzyme Induction; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Male; Mice; Mice, Inbred C57BL; STAT1 Transcription Factor; T-Lymphocytes | 2007 |
NMR studies on the interaction between (-)-epigallocatechin gallate and cyclodextrins, free and bonded to silica gels.
Topics: Catechin; Cyclodextrins; Magnetic Resonance Spectroscopy; Models, Molecular; Silicon Dioxide | 2007 |
Evaluation of the astringency of black tea by a taste sensor system: scope and limitation.
Topics: Biosensing Techniques; Catechin; Humans; Membrane Potentials; Reference Standards; Taste; Tea | 2007 |
[Separation of isomeric compounds by high speed countercurrent chromatography].
Topics: Aniline Compounds; Catechin; Countercurrent Distribution; Isomerism; Tea | 2006 |
Single GUV method reveals interaction of tea catechin (-)-epigallocatechin gallate with lipid membranes.
Topics: Camellia sinensis; Catechin; Diffusion; Lipid Bilayers; Liposomes; Membrane Fluidity; Phosphatidylcholines; Surface Properties | 2007 |
Attomole catechins determination by capillary liquid chromatography with electrochemical detection.
Topics: Catechin; Chromatography, Liquid; Electrochemistry; Humans; Methanol; Phosphoric Acids; Reproducibility of Results; Sensitivity and Specificity; Tea; Time Factors; Water | 2007 |
Epigallocatechin-3-gallate(-)protects Chang liver cells against ethanol-induced cytotoxicity and apoptosis.
Topics: Antioxidants; Apoptosis; Catechin; Cell Culture Techniques; Cell Line; Cell Survival; Central Nervous System Depressants; Ethanol; Glutathione; Glutathione Disulfide; Humans; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Mitochondria; Reactive Oxygen Species | 2007 |
Do the dietary supplements epigallocatechin gallate or vitamin e cause a radiomodifying response on tumors in vivo? A pilot study with murine breast carcinoma.
Topics: Animals; Apoptosis; Breast Neoplasms; Carcinoma; Catechin; Cell Proliferation; Cells, Cultured; Combined Modality Therapy; Dietary Supplements; Female; Mice; Mice, Inbred C3H; Neovascularization, Pathologic; Pilot Projects; Radiation-Protective Agents; Vitamin E | 2007 |
Glucuronide transport across the endoplasmic reticulum membrane is inhibited by epigallocatechin gallate and other green tea polyphenols.
Topics: Animals; Anticarcinogenic Agents; Biological Transport; Catechin; Cell Line, Tumor; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Enzyme Activation; Flavonoids; Glucuronidase; Glucuronides; Male; Microsomes, Liver; Molecular Structure; Phenols; Polyphenols; Rats; Rats, Wistar; Tea | 2007 |
Oxidative coupling of the pyrogallol B-ring with a galloyl group during enzymatic oxidation of epigallocatechin 3-O-gallate.
Topics: Camellia sinensis; Catechin; Models, Chemical; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Phenylenediamines; Plant Extracts; Pyrogallol; Pyrus | 2007 |
The green tea compound, (-)-epigallocatechin-3-gallate downregulates N-cadherin and suppresses migration of bladder carcinoma cells.
Topics: Animals; Anticarcinogenic Agents; Cadherins; Catechin; Catenins; Cell Line, Tumor; Cell Movement; Down-Regulation; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Neoplasm Transplantation; Signal Transduction; STAT3 Transcription Factor; Tea; Transplantation, Heterologous; Urinary Bladder Neoplasms | 2007 |
The potential benefits of green tea in patients with uveitis.
Topics: Anti-Inflammatory Agents; Antioxidants; Catechin; Clinical Trials as Topic; Folic Acid; Humans; Immunosuppressive Agents; Inflammation; Methotrexate; Models, Biological; Models, Theoretical; Tea; Uveitis | 2007 |
(-)-Epigallocatechin gallate suppresses endothelin-1-induced interleukin-6 synthesis in osteoblasts: inhibition of p44/p42 MAP kinase activation.
Topics: Animals; Anthracenes; Catechin; Cells, Cultured; Endothelin-1; Enzyme Activation; Flavonoids; Imidazoles; Interleukin-6; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-raf; Pyridines; Tetradecanoylphorbol Acetate | 2007 |
The comparison of effect of catechins and green tea extract on oxidative modification of LDL in vitro.
Topics: Antioxidants; Catechin; Humans; Lipid Peroxidation; Lipoproteins, LDL; Oxidation-Reduction; Plant Extracts; Tea; Time Factors | 2006 |
Epigallocatechin gallate, a green tea polyphenol, mediates NO-dependent vasodilation using signaling pathways in vascular endothelium requiring reactive oxygen species and Fyn.
Topics: Animals; Antioxidants; Aorta; Catechin; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Male; Mitogen-Activated Protein Kinase Kinases; Nitric Oxide; Nitric Oxide Synthase Type III; Phenols; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Polyphenols; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-fyn; Rats; Rats, Inbred WKY; Reactive Oxygen Species; Signal Transduction; Splanchnic Circulation; Tea; Vasodilation | 2007 |
Protein kinase CK2 modulates apoptosis induced by resveratrol and epigallocatechin-3-gallate in prostate cancer cells.
Topics: Apoptosis; Casein Kinase II; Caspase 3; Catechin; Cell Proliferation; Drug Therapy, Combination; Humans; Immunoblotting; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Resveratrol; Signal Transduction; Stilbenes; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured | 2007 |
Green tea polyphenols reduce autoimmune symptoms in a murine model for human Sjogren's syndrome and protect human salivary acinar cells from TNF-alpha-induced cytotoxicity.
Topics: Animals; Autoimmunity; Catechin; Cell Line; Cell Survival; Disease Models, Animal; Flavonoids; Humans; Imidazoles; Lymphocytes; MAP Kinase Kinase 4; MAP Kinase Kinase Kinases; Mice; Mice, Inbred NOD; p38 Mitogen-Activated Protein Kinases; Phenols; Phosphorylation; Plant Extracts; Polyphenols; Pyridines; Salivary Glands; Sjogren's Syndrome; Tea; Tumor Necrosis Factor-alpha | 2007 |
SHP-2 tyrosine phosphatase inhibits p73-dependent apoptosis and expression of a subset of p53 target genes induced by EGCG.
Topics: Animals; Apoptosis; Catechin; DNA-Binding Proteins; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; In Situ Nick-End Labeling; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Mice; Nuclear Proteins; Oxidative Stress; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Tea; Transcriptional Activation; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2007 |
Direct inhibition of insulin-like growth factor-I receptor kinase activity by (-)-epigallocatechin-3-gallate regulates cell transformation.
Topics: Animals; Anticarcinogenic Agents; Blotting, Western; Catechin; Cell Transformation, Neoplastic; Mice; Mice, Nude; Phenotype; Receptor, IGF Type 1; Signal Transduction | 2007 |
(-)-Epigallocatechin-3-gallate inhibits monocyte chemotactic protein-1 expression in endothelial cells via blocking NF-kappaB signaling.
Topics: Blotting, Northern; Blotting, Western; Catechin; Cell Movement; Chemokine CCL2; Culture Media; Electrophoretic Mobility Shift Assay; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Humans; Monocytes; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Signal Transduction; Tetradecanoylphorbol Acetate | 2007 |
Improving effects of epigallocatechin-3-gallate on hemorheological abnormalities of aging Guinea pigs.
Topics: Administration, Oral; Aging; Animals; Antioxidants; Biological Transport; Blood Viscosity; Catechin; Erythrocyte Aggregation; Erythrocyte Deformability; Erythrocyte Membrane; Guinea Pigs; Malondialdehyde; Oxygen; Random Allocation | 2007 |
Use of tea extracts (Camelia sinensis) in jelly candies as polyphenols sources in human diet.
Topics: Agar; Antioxidants; Candy; Catechin; Consumer Behavior; Dose-Response Relationship, Drug; Flavonoids; Food Technology; Gelatin; Humans; Oxidation-Reduction; Phenols; Plant Extracts; Polyphenols; Taste; Tea | 2007 |
Chemiluminescence analysis of the prooxidant and antioxidant effects of epigallocatechin-3-gallate.
Topics: Antioxidants; Ascorbic Acid; Catechin; DNA Damage; Dose-Response Relationship, Drug; Food, Organic; Humans; Hydrogen Peroxide; Iron; Luminescence; Oxidation-Reduction; Reactive Oxygen Species; Superoxides; Tea | 2007 |
Structure-reactivity relationships of flavan-3-ols on product generation in aqueous glucose/glycine model systems.
Topics: Catechin; Flavonoids; Glucose; Glycine; Maillard Reaction; Phenols; Pyrazines; Structure-Activity Relationship | 2007 |
Epigallocatechin gallate dose-dependently induces apoptosis or necrosis in human MCF-7 cells.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Catechin; Cell Line, Tumor; Dose-Response Relationship, Drug; Female; Humans; Necrosis; Reactive Oxygen Species | 2007 |
Epigallocatechin gallate inhibits phorbol ester-induced activation of NF-kappa B and CREB in mouse skin: role of p38 MAPK.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2 Inhibitors; Female; Mice; Mice, Inbred ICR; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Skin; Tetradecanoylphorbol Acetate | 2007 |
Inhibition of hepatic glucose 6-phosphatase system by the green tea flavanol epigallocatechin gallate.
Topics: Animals; Catechin; Flavonols; Glucose; Glucose-6-Phosphatase; Glucose-6-Phosphate; Liver; Microsomes, Liver; Rats; Tea | 2007 |
Anti-atherogenic effects of a mixture of ascorbic acid, lysine, proline, arginine, cysteine, and green tea phenolics in human aortic smooth muscle cells.
Topics: Amino Acids; Animals; Aorta; Ascorbic Acid; Atherosclerosis; Catechin; Cattle; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Dose-Response Relationship, Drug; Humans; Immunochemistry; Interleukin-6; Matrix Metalloproteinase 2; Myocytes, Smooth Muscle; Phenols; Plant Extracts; Tea | 2007 |
Concise synthesis of dideoxy-epigallocatechin gallate (DO-EGCG) and evaluation of its anti-influenza virus activity.
Topics: Alphainfluenzavirus; Animals; Antiviral Agents; Catechin; Cells, Cultured; Dogs | 2007 |
Suppression of postprandial hypertriglyceridemia in rats and mice by oolong tea polymerized polyphenols.
Topics: Animals; Catechin; Flavonoids; Hypertriglyceridemia; Lymphatic System; Male; Mice; Mice, Inbred C57BL; Phenols; Polyphenols; Postprandial Period; Rats; Rats, Sprague-Dawley; Tea; Triglycerides | 2007 |
[Green tea against AIDS?].
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Catechin; CD4-Positive T-Lymphocytes; Humans; Models, Molecular; Tea | 2007 |
Tea polyphenols inhibit rat vascular smooth muscle cell adhesion and migration on collagen and laminin via interference with cell-ECM interaction.
Topics: Animals; Antioxidants; Catechin; Cell Adhesion; Cell Line; Cell Movement; Collagen; Extracellular Matrix; Flavonoids; Laminin; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenols; Polyphenols; Rats; Tea | 2007 |
Tea polyphenol inhibits allostimulation in mixed lymphocyte culture.
Topics: Animals; Apoptosis; Catechin; Cell Proliferation; Cells, Cultured; Female; Flavonoids; Flow Cytometry; Immunosuppressive Agents; Interleukin-2; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Phenols; Plant Extracts; Polyphenols; Tea | 2007 |
Green tea catechins upregulate superoxide dismutase and catalase in fruit flies.
Topics: Animals; Catalase; Catechin; Drosophila melanogaster; Gene Expression Regulation, Enzymologic; Superoxide Dismutase; Tea; Up-Regulation | 2007 |
Epigallocatechin-3-gallate suppresses NF-kappaB activation and phosphorylation of p38 MAPK and JNK in human astrocytoma U373MG cells.
Topics: Amyloid beta-Peptides; Anti-Inflammatory Agents; Astrocytoma; Catechin; Cyclooxygenase 2; Dinoprostone; Humans; Interleukin-1beta; Interleukin-6; Interleukin-8; JNK Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphorylation; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2007 |
Effects of polyphenols on skin damage due to ultraviolet A rays: an experimental study on rats.
Topics: Animals; Catechin; Chi-Square Distribution; Collagen; Flavonoids; Phenols; Polyphenols; Radiation-Protective Agents; Rats; Rats, Wistar; Skin; Sunburn; Ultraviolet Rays | 2007 |
(-)-Epigallocatechin-3-gallate inhibits growth of gastric cancer by reducing VEGF production and angiogenesis.
Topics: Animals; Anticarcinogenic Agents; Carcinoma; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Endothelial Cells; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; STAT3 Transcription Factor; Stomach Neoplasms; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2007 |
(-)-Epigallocatechin gallate induces apoptosis, via caspase activation, in osteoclasts differentiated from RAW 264.7 cells.
Topics: Acid Phosphatase; Alveolar Process; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Bone Resorption; Caspase Inhibitors; Caspases; Catechin; Cell Line; Cell Survival; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Isoenzymes; Mice; Osteoclasts; RANK Ligand; Tartrate-Resistant Acid Phosphatase | 2007 |
Sample stacking for the analysis of catechins by microemulsion EKC.
Topics: Beverages; Catechin; Chromatography, Micellar Electrokinetic Capillary; Cyclohexanols; Emulsions; Food Analysis; Heptanes; Online Systems; Sodium Dodecyl Sulfate; Surface-Active Agents; Tea; Vitis; Wine | 2007 |
Methylation suppresses the proteasome-inhibitory function of green tea polyphenols.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Death; Flavonoids; Humans; Jurkat Cells; Methylation; Phenols; Polyphenols; Protease Inhibitors; Proteasome Inhibitors; Tea | 2007 |
Weight gain and psychiatric treatment: Is there a role for green tea and conjugated linoleic acid?
Topics: Adult; Body Fat Distribution; Catechin; Dibenzothiazepines; Female; Humans; Linoleic Acids, Conjugated; Male; Psychotropic Drugs; Quetiapine Fumarate; Tea; Thinness; Weight Gain | 2007 |
Green tea polyphenol epigallocatechin-3-gallate inhibits oxidative damage and preventive effects on carbon tetrachloride-induced hepatic fibrosis.
Topics: Animals; Beverages; Carbon Tetrachloride Poisoning; Catechin; Cell Culture Techniques; Disease Models, Animal; Disease Progression; Enzyme Activation; Liver; Liver Cirrhosis; Male; Matrix Metalloproteinase 2; Rats; Rats, Sprague-Dawley; Rats, Wistar | 2007 |
A novel prodrug of the green tea polyphenol (-)-epigallocatechin-3-gallate as a potential anticancer agent.
Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Catechin; Cell Growth Processes; Cell Line, Tumor; Chromatography, High Pressure Liquid; Chymotrypsin; Female; Humans; Mice; Mice, Nude; Peracetic Acid; Prodrugs; Protease Inhibitors; Xenograft Model Antitumor Assays | 2007 |
LNCaP cells exposed to ceramic drug delivery treatment with epigallocatechin-3-gallate, thymoquinone, and tannic acid.
Topics: Anticarcinogenic Agents; Antioxidants; Benzoquinones; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Ceramics; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Humans; Male; Neoplasm Proteins; Prostatic Neoplasms; Tannins | 2007 |
A comparison of 5-fluorouracil and natural chemotherapeutic agents, EGCG and thymoquinone, delivered by sustained drug delivery on colon cancer cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Benzoquinones; Catechin; Cell Proliferation; Cell Survival; Colonic Neoplasms; Delayed-Action Preparations; Dose-Response Relationship, Drug; Fluorouracil; Humans; Phytotherapy; Plant Extracts; Treatment Outcome; Tumor Cells, Cultured | 2007 |
Physiological responses of ES-2 ovarian cell line following administration of epigallocatechin-3-gallate (EGCG), thymoquinone (TQ), and selenium (SE).
Topics: Antineoplastic Agents; Antioxidants; Benzoquinones; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Neoplasm Proteins; Ovarian Neoplasms; Selenium | 2007 |
Potential mechanisms for the synergistic cytotoxicity elicited by 4-hydroxytamoxifen and epigallocatechin gallate in MDA-MB-231 cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Flow Cytometry; Humans; Tamoxifen | 2007 |
Role of Zn2+ in epigallocatechin gallate affecting the growth of PC-3 cells.
Topics: Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Cell Survival; Humans; Male; Prostatic Neoplasms; Tea; Zinc | 2007 |
Effects of (-)-epigallocatechin-3-gallate in Ca2+ -permeable non-selective cation channels and voltage-operated Ca2+ channels in vascular smooth muscle cells.
Topics: Animals; Antioxidants; Aorta; Calcium; Calcium Channel Blockers; Calcium Channels; Catechin; Cations; Imidazoles; Male; Muscle, Smooth, Vascular; Myocytes, Cardiac; Patch-Clamp Techniques; Rats; Rats, Wistar | 2007 |
Interactions between a non glycosylated human proline-rich protein and flavan-3-ols are affected by protein concentration and polyphenol/protein ratio.
Topics: Amino Acid Sequence; Catechin; Flavonoids; Glycosylation; Humans; Kinetics; Peptide Fragments; Peptides; Phenols; Polyphenols; Proline-Rich Protein Domains; Salivary Proteins and Peptides | 2007 |
Epigallocatechin-3-gallate and epicatechin-3-gallate from green tea decrease plasma non-transferrin bound iron and erythrocyte oxidative stress.
Topics: beta-Thalassemia; Catechin; Cells, Cultured; Erythrocytes; Free Radical Scavengers; Humans; Iron; Iron Chelating Agents; Iron Overload; Oxidative Stress; Tea | 2007 |
Epigallocatechin-3 gallate prevents cardiac hypertrophy induced by pressure overload in rats.
Topics: Animals; Blood Pressure; Cardiomegaly; Catechin; Echocardiography; Heart Rate; Histocytochemistry; Male; Organ Size; Rats; Rats, Sprague-Dawley | 2007 |
Chemopreventive effect of aerosolized polyphenon E on lung tumorigenesis in A/J mice.
Topics: Aerosols; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Catechin; Female; Lung Neoplasms; Mice | 2007 |
Investigation of adsorption behavior of (-)-epigallocatechin gallate on bovine serum albumin surface using quartz crystal microbalance with dissipation monitoring.
Topics: Adsorption; Catechin; Chemical Phenomena; Chemistry, Physical; Crystallization; Elasticity; Quartz; Serum Albumin, Bovine; Viscosity | 2007 |
Tea polyphenol (-)-epigallocatechin 3-gallate suppresses heregulin-beta1-induced fatty acid synthase expression in human breast cancer cells by inhibiting phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase cascade signaling.
Topics: Breast Neoplasms; Catechin; Cell Line, Tumor; Fatty Acid Synthases; Gene Expression Regulation, Enzymologic; Humans; Mitogen-Activated Protein Kinases; Neuregulin-1; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction; Tea | 2007 |
Effects of epigallocatechin gallate on diethyldithiocarbamate-induced pancreatic fibrosis in rats.
Topics: Actins; Administration, Oral; Animals; Catechin; Collagen; Ditiocarb; Dose-Response Relationship, Drug; Fibrosis; Histocytochemistry; Immunohistochemistry; Male; Molecular Structure; Molecular Weight; Muscle, Smooth; Pancreatic Diseases; Random Allocation; Rats; Rats, Wistar; RNA, Messenger; Smad3 Protein; Smad7 Protein; Time Factors; Transforming Growth Factor beta1 | 2007 |
A para-amino substituent on the D-ring of green tea polyphenol epigallocatechin-3-gallate as a novel proteasome inhibitor and cancer cell apoptosis inducer.
Topics: Apoptosis; B-Lymphocytes; Caspase 3; Catechin; Cell Line, Tumor; Humans; Leukemia; Molecular Structure; Proteasome Endopeptidase Complex; Structure-Activity Relationship; Tea | 2007 |
The green tea polyphenol epigallocatechin-3-gallate improves systemic hemodynamics and survival in rodent models of polymicrobial sepsis.
Topics: Animals; Blood Pressure; Catechin; Disease Models, Animal; Gene Expression; Lung; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Sprague-Dawley; Sepsis; Survival Rate | 2007 |
Chemotherapy enhances CD8(+) T cell-mediated antitumor immunity induced by vaccination with vaccinia virus.
Topics: Animals; Antineoplastic Agents; Catechin; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cyclophosphamide; Female; Lysosomal-Associated Membrane Protein 1; Mice; Mice, Inbred C57BL; Neoplasms; Papillomavirus E7 Proteins; Protein Sorting Signals; Vaccination; Vaccinia virus | 2007 |
[Interaction of ctDNA and EGCG-Cu(II) complex].
Topics: Animals; Catechin; Cattle; Copper; DNA; Hydrogen-Ion Concentration; Molecular Structure; Spectrometry, Fluorescence; Spectrophotometry | 2007 |
Anti-tumor effect of ascorbic acid, lysine, proline, arginine, and epigallocatechin gallate on prostate cancer cell lines PC-3, LNCaP, and DU145.
Topics: Antioxidants; Arginine; Ascorbic Acid; Catechin; Cell Line, Tumor; Cell Proliferation; Chemistry, Pharmaceutical; Collagen; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Formazans; Humans; Laminin; Lysine; Male; Matrix Metalloproteinases; Neoplasm Invasiveness; Proline; Prostatic Neoplasms; Proteoglycans; Tetrazolium Salts | 2004 |
Epigallocatechin-3-gallate inhibits cell cycle and induces apoptosis in pancreatic cancer.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Caspase 3; Catechin; Cell Cycle; Cell Line, Tumor; Enzyme Activation; Humans; MAP Kinase Signaling System; Mice; Mice, Knockout; Mitochondria; Pancreatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species | 2007 |
Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG.
Topics: Adenocarcinoma; Apoptosis; Breast Neoplasms; Catechin; Cell Division; Cell Line, Tumor; DNA Methylation; E2F1 Transcription Factor; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histones; HL-60 Cells; Humans; Lysine; Male; Methylation; Neoplasm Proteins; Promoter Regions, Genetic; Protein Processing, Post-Translational; RNA, Messenger; RNA, Neoplasm; Telomerase | 2008 |
Comparison of white tea, green tea, epigallocatechin-3-gallate, and caffeine as inhibitors of PhIP-induced colonic aberrant crypts.
Topics: Animals; Anticarcinogenic Agents; Caffeine; Carcinogens; Catechin; Cell Division; Colon; Colonic Neoplasms; Humans; Imidazoles; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Tea | 2007 |
Epigallocatechin gallate, an active ingredient from green tea, attenuates damaging influences to the retina caused by ischemia/reperfusion.
Topics: Analysis of Variance; Animals; Apoptosis; Caspase 3; Catechin; Choline O-Acetyltransferase; Dose-Response Relationship, Drug; Drug Interactions; Electroretinography; Eye Proteins; Glial Fibrillary Acidic Protein; Hydrogen Peroxide; Neuroprotective Agents; Rats; Rats, Wistar; Reperfusion Injury; Retinal Diseases; Retinal Ganglion Cells; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Thy-1 Antigens | 2007 |
Activation of FOXO3a by the green tea polyphenol epigallocatechin-3-gallate induces estrogen receptor alpha expression reversing invasive phenotype of breast cancer cells.
Topics: Animals; Anticarcinogenic Agents; Beverages; Breast Neoplasms; Cadherins; Catechin; Estrogen Receptor alpha; Female; Flavonoids; Forkhead Box Protein O3; Forkhead Transcription Factors; gamma Catenin; Gene Expression; Gene Expression Profiling; Humans; Immunoblotting; Neoplasm Invasiveness; Neoplasm Proteins; Phenols; Phenotype; Polyphenols; Receptor, ErbB-2; Reverse Transcriptase Polymerase Chain Reaction; Snail Family Transcription Factors; Transcription Factors; Transfection | 2007 |
The green tea polyphenol, epigallocatechin-3-gallate inhibits telomerase and induces apoptosis in drug-resistant lung cancer cells.
Topics: Anticarcinogenic Agents; Apoptosis; Camellia sinensis; Catechin; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Neoplasms; Plant Extracts; Telomerase | 2007 |
Epigallocatechin gallate (EGCG) suppresses beta-amyloid-induced neurotoxicity through inhibiting c-Abl/FE65 nuclear translocation and GSK3 beta activation.
Topics: Active Transport, Cell Nucleus; Amyloid beta-Peptides; Apoptosis; Catechin; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Proto-Oncogene Proteins c-abl | 2009 |
Epigallocatechin-3-gallate and bicalutamide cause growth arrest and apoptosis in NRP-152 and NRP-154 prostate epithelial cells.
Topics: Anilides; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Catechin; Cell Count; Cell Division; Cell Line; Drug Synergism; Epithelial Cells; Immunohistochemistry; Male; Nitriles; Prostate; Rats; Rats, Wistar; Receptors, Androgen; Superoxide Dismutase; Tosyl Compounds | 2007 |
Autoxidative quinone formation in vitro and metabolite formation in vivo from tea polyphenol (-)-epigallocatechin-3-gallate: studied by real-time mass spectrometry combined with tandem mass ion mapping.
Topics: Animals; Catechin; Drug Stability; Kinetics; Male; Mass Spectrometry; Mice; Oxidation-Reduction; Quinones; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2007 |
Physiological levels of tea catechins increase cellular lipid antioxidant activity of vitamin C and vitamin E in human intestinal caco-2 cells.
Topics: Antioxidants; Ascorbic Acid; Caco-2 Cells; Catechin; Humans; Intestinal Mucosa; Intestines; Lipid Metabolism; Malondialdehyde; Tea; Vitamin E | 2007 |
Design, semisynthesis, and evaluation of O-acyl derivatives of (-)-epigallocatechin-3-gallate as antitumor agents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acylation; Animals; Antineoplastic Agents, Phytogenic; Catechin; Mice; Neoplasms, Experimental; Tea; Tetradecanoylphorbol Acetate | 2007 |
Solid-phase synthesis of epigallocatechin gallate derivatives.
Topics: Anticarcinogenic Agents; Antioxidants; Catechin; Methylation | 2007 |
The inhibitory effect of (-)-epigallocatechin gallate on activation of the epidermal growth factor receptor is associated with altered lipid order in HT29 colon cancer cells.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Catechin; Cell Membrane; Cross-Linking Reagents; Detergents; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Fluorescent Dyes; HT29 Cells; Humans; Membrane Microdomains; Octoxynol; Signal Transduction | 2007 |
Human gastric cells resistant to (-)-epigallocatechin gallate show cross-resistance to several environmental pollutants.
Topics: Arsenites; Carbamates; Catechin; Cell Line, Tumor; Cytoprotection; Dose-Response Relationship, Drug; Environmental Pollutants; Humans; Hydrogen Peroxide; Insecticides; Reactive Oxygen Species; Sodium Compounds; Stomach | 2007 |
The green tea component EGCG inhibits RNA polymerase III transcription.
Topics: Base Sequence; Catechin; HeLa Cells; Humans; Molecular Sequence Data; Promoter Regions, Genetic; RNA Polymerase III; TATA-Binding Protein Associated Factors; Tea; Transcription Factor TFIIIB; Transcription, Genetic | 2007 |
Epigallocatechin gallate-induced apoptosis does not affect adipocyte conversion of preadipocytes.
Topics: Adipocytes; Adipogenesis; Apoptosis; Apoptosis Regulatory Proteins; Catechin; Cell Line; Cell Survival; fas Receptor; Humans; PPAR gamma | 2007 |
Tea epigallocatechin-3-gallate increases 8-isoprostane level and induces caudal regression in developing rat embryos.
Topics: Animals; Antioxidants; Apoptosis; Catechin; Dinoprost; Embryo, Mammalian; Female; In Situ Nick-End Labeling; Plant Extracts; Pregnancy; Rats; Rats, Sprague-Dawley; Tea | 2007 |
A novel approach of proteomics and transcriptomics to study the mechanism of action of the antioxidant-iron chelator green tea polyphenol (-)-epigallocatechin-3-gallate.
Topics: Antioxidants; Blotting, Western; Catechin; Cell Line, Tumor; Electrophoresis, Gel, Two-Dimensional; Flavonoids; Gene Expression; Humans; Image Processing, Computer-Assisted; Iron Chelating Agents; Neurons; Neuroprotective Agents; Phenols; Plant Extracts; Polyphenols; Proteomics; Reverse Transcriptase Polymerase Chain Reaction; Tea; Transcription, Genetic | 2007 |
Epigallocatechin gallate suppresses expression of receptor activator of NF-kappaB ligand (RANKL) in Staphylococcus aureus infection in osteoblast-like NRG cells.
Topics: Animals; Catechin; Cytokines; Mice; Osteoblasts; Protease Inhibitors; RANK Ligand; Staphylococcal Infections; Staphylococcus aureus | 2007 |
Uncoupling by (--)-epigallocatechin-3-gallate of ATP-sensitive potassium channels from phosphatidylinositol polyphosphates and ATP.
Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Blood Glucose; Calcium; Catechin; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Insulin; Insulin-Secreting Cells; Ion Channel Gating; Male; Membrane Potentials; Mice; Molecular Structure; Multidrug Resistance-Associated Proteins; Myocytes, Cardiac; Neomycin; Oocytes; Phosphatidylinositol Phosphates; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Drug; Structure-Activity Relationship; Sulfonylurea Receptors; Xenopus laevis | 2007 |
Inhibition of epigallocatechin gallate on orthotopic colon cancer by upregulating the Nrf2-UGT1A signal pathway in nude mice.
Topics: Animals; Anticarcinogenic Agents; Catechin; Colonic Neoplasms; Glucuronosyltransferase; HT29 Cells; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; NF-E2-Related Factor 2; RNA, Messenger; Signal Transduction | 2007 |
Synergistic effects of a combination of dietary factors sulforaphane and (-) epigallocatechin-3-gallate in HT-29 AP-1 human colon carcinoma cells.
Topics: Catechin; Cell Survival; Cellular Senescence; Colonic Neoplasms; Drug Synergism; HT29 Cells; Humans; Hydroxamic Acids; Isothiocyanates; Reactive Oxygen Species; Sulfoxides; Superoxide Dismutase; Thiocyanates; Transcription Factor AP-1; Transcriptional Activation | 2008 |
Relationship between the biological activities of methylated derivatives of (-)-epigallocatechin-3-O-gallate (EGCG) and their cell surface binding activities.
Topics: Basophils; Catechin; Cell Line; Cell Membrane; Humans; Methylation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Structure-Activity Relationship | 2007 |
(-)-Epigallocatechin gallate, the most active polyphenolic catechin in green tea, presynaptically facilitates Ca2+-dependent glutamate release via activation of protein kinase C in rat cerebral cortex.
Topics: 4-Aminopyridine; Analysis of Variance; Animals; Calcium; Catechin; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; Male; Membrane Potentials; Potassium Channel Blockers; Presynaptic Terminals; Protein Kinase C; Rats; Rats, Sprague-Dawley; Synaptosomes | 2007 |
Protective effect of (-)-epigallocatechin gallate against advanced glycation endproducts-induced injury in neuronal cells.
Topics: Annexin A5; Antioxidants; Apoptosis; Catalase; Catechin; Cell Line, Tumor; Cell Survival; Glutathione Peroxidase; Glycation End Products, Advanced; Humans; Indicators and Reagents; Lipid Peroxidation; Malondialdehyde; Neuroblastoma; Neurons; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Superoxide Dismutase | 2007 |
Neuroprotective effects of quercetin and rutin on spatial memory impairment in an 8-arm radial maze task and neuronal death induced by repeated cerebral ischemia in rats.
Topics: Animals; Brain Ischemia; Catechin; Cell Death; Disease Models, Animal; Flavonoids; Hippocampus; Male; Maze Learning; Memory; Neurons; Neuroprotective Agents; Quercetin; Rats; Rats, Wistar; Rutin; Space Perception; Structure-Activity Relationship | 2007 |
Trypanosoma cruzi: in vitro and in vivo antiproliferative effects of epigallocatechin gallate (EGCg).
Topics: Animals; Antioxidants; Catechin; Chagas Disease; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Hepatocytes; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred BALB C; Parasitemia; Random Allocation; Trypanocidal Agents; Trypanosoma cruzi | 2007 |
Epigallocatechin gallate attenuates experimental non-alcoholic steatohepatitis induced by high fat diet.
Topics: Animals; Antioxidants; Catechin; Diet; Dietary Fats; Disease Models, Animal; Fatty Liver; Liver; Male; Rats; Rats, Sprague-Dawley | 2008 |
Effects of folate cycle disruption by the green tea polyphenol epigallocatechin-3-gallate.
Topics: Adenosine; Apoptosis; Caco-2 Cells; Camellia sinensis; Caspase 3; Catechin; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; DNA Replication; Fluorouracil; Folic Acid Antagonists; Gene Expression; Humans; Hypoxanthine; Leucovorin; Models, Biological; NF-kappa B; Protein Binding; Receptor, Adenosine A3; Tetrahydrofolate Dehydrogenase; Thymine; Transcription, Genetic | 2007 |
Modulation of human glutathione s-transferases by polyphenon e intervention.
Topics: Catechin; Female; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Lymphocytes; Male; Protease Inhibitors; Tea | 2007 |
Common tea formulations modulate in vitro digestive recovery of green tea catechins.
Topics: Animals; Beverages; Bile; Catechin; Chromatography, High Pressure Liquid; Citrus; Digestion; Drug Stability; Food Additives; Fruit; Hydrogen-Ion Concentration; In Vitro Techniques; Lipase; Milk; Oryza; Pancreatin; Pepsin A; Soy Milk; Tea | 2007 |
Dietary supplementation with epigallocatechin gallate elevates levels of circulating adiponectin in non-obese type-2 diabetic Goto-Kakizaki rats.
Topics: Adiponectin; Animals; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Supplements; Lipid Metabolism; Rats; Rats, Inbred Strains; Triglycerides | 2007 |
Characterizing the spatio-temporal behavior of cell populations through image auto- and cross-correlation microscopy.
Topics: Animals; Catechin; Cell Aggregation; Cell Line; Cell Movement; Cell Survival; Cells; Computer Simulation; Humans; Image Processing, Computer-Assisted; Mice; Microscopy; Neoplasms; Time Factors | 2007 |
Apoptotic effect of Epigallocatechin-3-gallate on the human gastric cancer cell line MKN45 via activation of the mitochondrial pathway.
Topics: Anticarcinogenic Agents; Apoptosis; Caspase 3; Catechin; Cell Line, Tumor; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Membrane Potential, Mitochondrial; Mitochondria; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Stomach Neoplasms; Time Factors | 2007 |
Inhibition of tumorigenesis in ApcMin/+ mice by a combination of (-)-epigallocatechin-3-gallate and fish oil.
Topics: Adenomatous Polyposis Coli; Animals; Anticarcinogenic Agents; Catechin; Dietary Fats; Female; Fish Oils; Germ-Line Mutation; Intestinal Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic | 2007 |
Epigallocatechin-3-Gallate suppresses early stage, but not late stage prostate cancer in TRAMP mice: mechanisms of action.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Proliferation; Drug Screening Assays, Antitumor; Insulin-Like Growth Factor I; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Transgenic; Prostate; Prostatic Neoplasms; Receptor, IGF Type 1; Receptors, Androgen | 2007 |
Concentration decrease of nitric oxide in the postischemic muscle is not only caused by the generation of O2-.
Topics: Animals; Antioxidants; Catechin; Hindlimb; Infusions, Intravenous; Ischemia; Male; Muscles; Nitric Oxide; Oxygen; Rats; Rats, Wistar; Reperfusion Injury; Signal Processing, Computer-Assisted; Superoxides | 2007 |
Inhibition of NADPH oxidase subunits translocation by tea catechin EGCG in mast cell.
Topics: Animals; beta-N-Acetylhexosaminidases; Blotting, Western; Catechin; Cell Line, Tumor; Cell Membrane; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Humans; Mast Cells; NADPH Oxidases; Neutrophils; Onium Compounds; p-Methoxy-N-methylphenethylamine; Phosphoproteins; Protease Inhibitors; Protein Subunits; Protein Transport; Reactive Oxygen Species; Tea; Time Factors | 2007 |
Theaflavins attenuate hepatic lipid accumulation through activating AMPK in human HepG2 cells.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Biflavonoids; Catechin; Dietary Fats; Enzyme Activation; Humans; Lipid Metabolism; Liver; Male; Multienzyme Complexes; Protein Serine-Threonine Kinases; Rats; Rats, Wistar | 2007 |
Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, suppresses hepatic gluconeogenesis through 5'-AMP-activated protein kinase.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Catechin; Gluconeogenesis; Hepatocytes; Hydrogen Peroxide; Insulin; Liver; Mice; Models, Biological; Multienzyme Complexes; Protein Serine-Threonine Kinases; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Tea | 2007 |
Semaphorin3A accelerates neuronal polarity in vitro and in its absence the orientation of DRG neuronal polarity in vivo is distorted.
Topics: Animals; Axons; Catechin; Cell Movement; Cell Polarity; Cells, Cultured; Chi-Square Distribution; Dendrites; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Female; Ganglia, Spinal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Mice, Knockout; Neurons; Pregnancy; Semaphorin-3A; Time Factors; Tubulin | 2007 |
Externally applied pressure activates pancreatic stellate cells through the generation of intracellular reactive oxygen species.
Topics: Acetylcysteine; Animals; Antioxidants; Catechin; Kinetics; Models, Animal; Pancreas; Pancreatitis; Pressure; Rats; Reactive Oxygen Species; Reference Values; Superoxide Dismutase | 2007 |
[Photo-protection of epigallocatechin-3-gallate on aging and gene mutation of human skin fibroblasts caused by ultraviolet radiation: an in vitro experiment].
Topics: beta-Galactosidase; Catechin; Cell Proliferation; Cells, Cultured; Cellular Senescence; Fibroblasts; Foreskin; Humans; Hypoxanthine Phosphoribosyltransferase; Infant; Male; Mutation; Ultraviolet Rays | 2007 |
Epigallocathechin-3-gallate in AL amyloidosis: a new therapeutic option?
Topics: Amyloidosis; Anticarcinogenic Agents; Catechin; Humans; Protease Inhibitors | 2007 |
Epigallocatechin-3 gallate induces growth inhibition and apoptosis in human breast cancer cells through survivin suppression.
Topics: Anticarcinogenic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Catechin; Cell Line, Tumor; Colony-Forming Units Assay; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Luciferases; Microtubule-Associated Proteins; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; Protease Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction; Survivin | 2007 |
Induction of apoptosis by epigallocatechin-3-gallate in human lymphoblastoid B cells.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Catechin; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Humans; Lymphoma, B-Cell; Reactive Oxygen Species; Signal Transduction | 2007 |
Temperance in green tea.
Topics: Animals; Antioxidants; Camellia sinensis; Catechin; Chemical and Drug Induced Liver Injury; Dietary Supplements; Humans; Liver Diseases; Plant Extracts; Tea | 2007 |
Synergic anticandidal effect of epigallocatechin-O-gallate combined with amphotericin B in a murine model of disseminated candidiasis and its anticandidal mechanism.
Topics: Amphotericin B; Animals; Antifungal Agents; Candida albicans; Candidiasis; Catechin; Drug Synergism; Female; Hyphae; Mice; Mice, Inbred BALB C | 2007 |
Different cytotoxic and clastogenic effects of epigallocatechin gallate in various cell-culture media due to variable rates of its oxidation in the culture medium.
Topics: Animals; Catalase; Catechin; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Culture Media; Female; Hydrogen Peroxide; Mutagens; Oxidation-Reduction | 2007 |
Myeloperoxidase is a key regulator of oxidative stress mediated apoptosis in myeloid leukemic cells.
Topics: Aniline Compounds; Antioxidants; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Heme; Humans; Leukemia, Myeloid, Acute; Oxidative Stress; Peroxidase; Reactive Oxygen Species; Superoxides | 2007 |
Inhibitory effects of various beverages on human recombinant sulfotransferase isoforms SULT1A1 and SULT1A3.
Topics: Adrenergic beta-Agonists; Arylsulfotransferase; Beverages; Biflavonoids; Biological Availability; Catechin; Citrus paradisi; Citrus sinensis; Flavanones; Flavones; Herb-Drug Interactions; Humans; In Vitro Techniques; Phenols; Polyphenols; Quercetin; Sulfotransferases; Tea | 2007 |
(-)-Epigallocatechin-3-gallate interferes with mast cell adhesiveness, migration and its potential to recruit monocytes.
Topics: Antineoplastic Agents; Catechin; Cell Adhesion; Cell Line; Cell Movement; Gene Expression Profiling; Gene Expression Regulation; Humans; Integrins; Mast Cells; Monocytes; Neovascularization, Physiologic | 2007 |
Enhancement of antibacterial effects of epigallocatechin gallate, using ascorbic acid.
Topics: Anti-Bacterial Agents; Ascorbic Acid; Catechin; Methicillin-Resistant Staphylococcus aureus; Molecular Structure; Oxidation-Reduction; Time Factors | 2008 |
One-step purification of epigallocatechin gallate from crude green tea extracts by mixed-mode adsorption chromatography on highly cross-linked agarose media.
Topics: Acetonitriles; Catechin; Chemical Fractionation; Chromatography, High Pressure Liquid; Molecular Structure; Plant Extracts; Sepharose; Solvents; Tea; Water | 2007 |
Epigallocatechin gallate (EGCG) potentiates the cytotoxicity of rotenone in neuroblastoma SH-SY5Y cells.
Topics: Antioxidants; Brain; Catechin; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Synergism; Humans; Insecticides; Neuroblastoma; Neurons; Oxidative Stress; Parkinson Disease; Reactive Oxygen Species; Rotenone; Superoxides | 2007 |
Fatty acid metabolism in breast cancer cells: differential inhibitory effects of epigallocatechin gallate (EGCG) and C75.
Topics: 4-Butyrolactone; Apoptosis; Breast Neoplasms; Carnitine O-Palmitoyltransferase; Catechin; Enzyme Inhibitors; Fatty Acid Synthases; Fatty Acids; Female; Humans; Signal Transduction | 2008 |
A new LC/MS/MS rapid and sensitive method for the determination of green tea catechins and their metabolites in biological samples.
Topics: Animals; Catechin; Chromatography, Liquid; Dogs; Glucuronides; Mass Spectrometry; Tea | 2007 |
Neurorescue activity, APP regulation and amyloid-beta peptide reduction by novel multi-functional brain permeable iron- chelating- antioxidants, M-30 and green tea polyphenol, EGCG.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antioxidants; Apoptosis; Catechin; Cell Line, Tumor; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Hydroxyquinolines; Mice; Mice, Inbred C57BL; Models, Biological; Neuroblastoma | 2007 |
Trastuzumab-resistant HER2-driven breast cancer cells are sensitive to epigallocatechin-3 gallate.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Catechin; Cell Growth Processes; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Forkhead Box Protein O3; Forkhead Transcription Factors; Humans; Intracellular Signaling Peptides and Proteins; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2; Signal Transduction; Trastuzumab | 2007 |
Green-tea polyphenol (-)-epigallocatechin-3-gallate provides resistance to apoptosis in isolated islets.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anoikis; Antioxidants; Catechin; Cell Hypoxia; Deoxyguanosine; Insulin; Islets of Langerhans; L-Lactate Dehydrogenase; Rats; Rats, Inbred F344; Reperfusion Injury; Tea | 2007 |
Catechin degradation with concurrent formation of homo- and heterocatechin dimers during in vitro digestion.
Topics: Catechin; Digestion; Dimerization; In Vitro Techniques; Lipase; Oxidation-Reduction; Pancreatin; Pepsin A | 2007 |
Inhibition of intestinal tumorigenesis in Apc(min/+) mice by green tea polyphenols (polyphenon E) and individual catechins.
Topics: Analysis of Variance; Animals; Anticarcinogenic Agents; Beverages; Biological Availability; Catechin; Cell Division; Diet; Drug Administration Routes; Female; Genes, APC; Immunohistochemistry; Intestinal Neoplasms; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-akt; Tea | 2007 |
Modifying effects of dietary factors on (-)-epigallocatechin-3-gallate-induced pro-matrix metalloproteinase-7 production in HT-29 human colorectal cancer cells.
Topics: Acetylcysteine; Antioxidants; Catechin; Colorectal Neoplasms; Culture Media; Curcumin; Gallic Acid; Genes, Reporter; HT29 Cells; Humans; Hydrogen Peroxide; Isothiocyanates; Luciferases; Matrix Metalloproteinase 7; RNA, Messenger; Transcription Factor AP-1 | 2007 |
Epigallocatechin-3-gallate (EGCG) inhibits PC-3 prostate cancer cell proliferation via MEK-independent ERK1/2 activation.
Topics: Anticarcinogenic Agents; Catechin; Cell Line; Cell Line, Tumor; Cell Proliferation; Chromones; Enzyme Activation; Epithelial Cells; Flavonoids; Humans; Inhibitory Concentration 50; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Prostatic Neoplasms; Protein Kinase Inhibitors | 2008 |
Epigallocatechin gallate affects human dendritic cell differentiation and maturation.
Topics: Antigen-Presenting Cells; Apoptosis; Catechin; Cell Differentiation; Cells, Cultured; Dendritic Cells; Humans; Immunosuppression Therapy; Interleukin-10; Monocytes; T-Lymphocytes | 2008 |
Neuroprotective effects of (-)-epigallocatechin-3-gallate (EGCG) on paraquat-induced apoptosis in PC12 cells.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Carrier Proteins; Caspase 3; Catechin; Cell Nucleus; Cell Survival; DNA Fragmentation; Membrane Potential, Mitochondrial; Mitochondrial Proteins; Neuroprotective Agents; Paraquat; PC12 Cells; Rats | 2008 |
Characterization of the constituents and antioxidant activity of Brazilian green tea (Camellia sinensis var. assamica IAC-259 cultivar) extracts.
Topics: Antioxidants; Brazil; Camellia sinensis; Catechin; Plant Extracts; Plant Leaves; Seasons | 2007 |
Purinergic regulation of angiogenesis by human breast carcinoma-secreted nucleoside diphosphate kinase.
Topics: Adenosine Triphosphate; Breast Neoplasms; Catechin; Cell Proliferation; Dose-Response Relationship, Drug; Ellagic Acid; Endothelial Cells; Humans; Neovascularization, Pathologic; Nucleoside-Diphosphate Kinase; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Tumor Cells, Cultured | 2007 |
The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Caspase 7; Catechin; Cell Growth Processes; Cell Line, Tumor; Dacarbazine; Down-Regulation; Drug Screening Assays, Antitumor; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Fluorouracil; Glioblastoma; Heat-Shock Proteins; Humans; Irinotecan; Molecular Chaperones; RNA, Small Interfering; Temozolomide; Transcription Factor CHOP; Transfection | 2007 |
Promotion of neuronal plasticity by (-)-epigallocatechin-3-gallate.
Topics: Animals; Catechin; Hippocampus; Long-Term Potentiation; Mice; Neuronal Plasticity | 2008 |
Epigallocatechin-3-gallate inhibits the invasion of human oral cancer cells and decreases the productions of matrix metalloproteinases and urokinase-plasminogen activator.
Topics: Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Cell Migration Assays; Cell Movement; Cell Survival; Epithelial Cells; Humans; Matrix Metalloproteinase Inhibitors; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Plant Extracts; Tea; Urokinase-Type Plasminogen Activator | 2007 |
Insulin signaling and the heat shock response modulate protein homeostasis in the Caenorhabditis elegans intestine during infection.
Topics: Animals; Animals, Genetically Modified; Antioxidants; Bacteria; Bacterial Proteins; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Catechin; Homeostasis; Hot Temperature; Insulin; Intestinal Mucosa; Intestines; Luminescent Proteins; Microscopy, Fluorescence; Muscles; Neurons; Oxidative Stress; Peptides; Signal Transduction; Thioctic Acid; Transcription Factors | 2008 |
Real-time imaging of beta-catenin dynamics in cells and living mice.
Topics: Animals; beta Catenin; Catechin; Cell Line; Humans; Luminescent Measurements; Mice; Signal Transduction; Time Factors; Transcription, Genetic; Wnt Proteins | 2007 |
[Inhibitory Effect of EGCG on angiogenesis induced by multiple myeloma cell line KM3 and its mechanism].
Topics: Angiogenesis Inhibitors; Catechin; Cell Line, Tumor; Down-Regulation; Humans; Multiple Myeloma; RNA, Messenger; Vascular Endothelial Growth Factor A | 2007 |
Effects of (-)-epigallocatechin gallate on the development of morphine-induced physical dependence.
Topics: Animals; Catechin; Cyclic AMP; Humans; Locus Coeruleus; Male; Mice; Mice, Inbred ICR; Morphine Dependence; Naloxone; Receptors, Dopamine D2; Signal Transduction; Substance Withdrawal Syndrome | 2007 |
Green tea flavonoid epigallocatechin-3-gallate (EGCG) inhibits cardiac hERG potassium channels.
Topics: Animals; Catechin; Cells, Cultured; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ion Channel Gating; Kidney; Oocytes; Potassium; Tea; Xenopus laevis | 2007 |
Induction of full-length survival motor neuron by polyphenol botanical compounds.
Topics: Alternative Splicing; Catechin; Cells, Cultured; Curcumin; Cyclic AMP Response Element-Binding Protein; Exons; Flavonoids; Humans; Models, Biological; Nerve Tissue Proteins; Phenols; Plants; Polyphenols; Resveratrol; RNA Precursors; RNA-Binding Proteins; SMN Complex Proteins; Stilbenes; Survival of Motor Neuron 1 Protein; Survival of Motor Neuron 2 Protein; Up-Regulation | 2008 |
Dynamic behavior of tea catechins interacting with lipid membranes as determined by NMR spectroscopy.
Topics: Catechin; Lipid Bilayers; Magnetic Resonance Spectroscopy; Structure-Activity Relationship; Tea | 2007 |
EGCG inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancer.
Topics: Animals; Catechin; Cell Proliferation; Endothelium, Vascular; Extracellular Signal-Regulated MAP Kinases; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Pancreatic Neoplasms | 2008 |
Epigallocatechin-3-O-gallate inhibits the angiotensin II-induced adhesion molecule expression in human umbilical vein endothelial cell via inhibition of MAPK pathways.
Topics: Angiotensin II; Catechin; Cell Membrane; Endothelial Cells; Enzyme Activation; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyridines; Umbilical Veins; Vascular Cell Adhesion Molecule-1 | 2007 |
A major ingredient of green tea rescues mice from lethal sepsis partly by inhibiting HMGB1.
Topics: Animals; Catechin; Cell Line; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; HMGB1 Protein; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Recombinant Proteins; Sepsis; Tea | 2007 |
Epigallocatechin gallate inhibits intracellular survival of Listeria monocytogenes in macrophages.
Topics: Animals; Anti-Bacterial Agents; Catechin; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Listeria monocytogenes; Macrophages; Mice; Mice, Inbred C3H | 2008 |
Combined effect of epigallocatechin gallate and triclosan on enoyl-ACP reductase of Mycobacterium tuberculosis.
Topics: Catechin; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Protein Binding; Protein Structure, Tertiary; Spectrometry, Fluorescence; Triclosan | 2008 |
Green tea polyphenol EGCG sensitizes human prostate carcinoma LNCaP cells to TRAIL-mediated apoptosis and synergistically inhibits biomarkers associated with angiogenesis and metastasis.
Topics: Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Camellia sinensis; Carcinoma; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; Humans; Male; Neovascularization, Pathologic; Prostatic Neoplasms; TNF-Related Apoptosis-Inducing Ligand | 2008 |
Tea polyphenol (-)-epigallocatechin-3-gallate: a new trapping agent of reactive dicarbonyl species.
Topics: Catechin; Chromatography, High Pressure Liquid; Flavonoids; Glycation End Products, Advanced; Glyoxal; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Phenols; Polyphenols; Pyruvaldehyde; Stereoisomerism; Tea | 2007 |
Black tea polyphenols mimic insulin/insulin-like growth factor-1 signalling to the longevity factor FOXO1a.
Topics: Animals; Biflavonoids; Catechin; Cell Line; Flavonoids; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Insulin; Insulin-Like Growth Factor I; Longevity; Phenols; Polyphenols; Protein Serine-Threonine Kinases; Rats; Signal Transduction; Tea | 2008 |
Therapeutic effect of epigallocatechin-3-gallate in a mouse model of colitis.
Topics: Animals; Antioxidants; Catechin; Colitis; Cytokines; Disease Models, Animal; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; NF-kappa B; Peroxidase; Tea; Transcription Factor AP-1; Trinitrobenzenesulfonic Acid | 2008 |
Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biomarkers, Tumor; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Curcumin; Diet; DNA Damage; Gene Expression Regulation, Neoplastic; Genistein; Humans; Indoles; Neoplasm Proteins; Neoplasms; RNA, Neoplasm; Time Factors | 2007 |
The behavior of vascular smooth muscle cells and platelets onto epigallocatechin gallate-releasing poly(l-lactide-co-epsilon-caprolactone) as stent-coating materials.
Topics: Animals; Biocompatible Materials; Blood Platelets; Catechin; Cell Movement; Cells, Cultured; Chemical Phenomena; Chemistry, Physical; Drug-Eluting Stents; Male; Microscopy, Electron, Scanning; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Platelet Activation; Polyesters; Rats; Rats, Sprague-Dawley; Spectroscopy, Fourier Transform Infrared | 2008 |
Antiproliferative effects of the major tea polyphenol, (-)-epigallocatechin gallate and retinoic acid in cervical adenocarcinoma.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 3; Catechin; Cell Growth Processes; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Synergism; Female; HeLa Cells; Humans; Telomerase; Tretinoin; Uterine Cervical Neoplasms | 2008 |
Green tea polyphenol and epigallocatechin gallate induce apoptosis and inhibit invasion in human breast cancer cells.
Topics: Adenocarcinoma; Apoptosis; Apoptosis Regulatory Proteins; beta Catenin; Breast Neoplasms; Catechin; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Phenols; Phosphorylation; Polyphenols; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Tea | 2007 |
(-)-Epigallocatechin-3-gallate downregulates estrogen receptor alpha function in MCF-7 breast carcinoma cells.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Survival; Down-Regulation; Estrogen Receptor alpha; Female; Humans; Tamoxifen; Trefoil Factor-1; Tumor Suppressor Proteins | 2007 |
Protective effects of epigallocatechin gallate after UV irradiation in cultured human retinal pigment epithelial cells.
Topics: Antioxidants; Catechin; Cell Count; Cells, Cultured; Dose-Response Relationship, Radiation; Humans; Pigment Epithelium of Eye; Radiation Injuries; Radiation-Protective Agents; Spectrophotometry; Ultraviolet Rays | 2007 |
Green tea catechin as a chemical chaperone in cancer prevention.
Topics: Catechin; Molecular Chaperones; Neoplasms; Protein Conformation | 2008 |
Inhibitory effect of (-)-epigallocatechin-3-gallate on lipid accumulation of 3T3-L1 cells.
Topics: 3T3-L1 Cells; Adaptor Proteins, Signal Transducing; Adipocytes; AMP-Activated Protein Kinase Kinases; Animals; Antioxidants; Catechin; Cell Differentiation; Cell Proliferation; Cell Survival; Cells, Cultured; DNA-Binding Proteins; Enzyme Activation; Glyceraldehyde-3-Phosphate Dehydrogenases; Insulin Receptor Substrate Proteins; Lipid Metabolism; Liver X Receptors; Mice; Orphan Nuclear Receptors; PPAR gamma; Protein Kinases; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Time Factors | 2007 |
Effect of dietary epigallocatechin-3-gallate on cytochrome P450 2E1-dependent alcoholic liver damage: enhancement of fatty acid oxidation.
Topics: Acetyl-CoA Carboxylase; Animals; Antioxidants; Aspartate Aminotransferases; Carnitine O-Palmitoyltransferase; Catechin; Cytochrome P-450 CYP2E1; Enzyme Activation; Fatty Liver, Alcoholic; Lipid Peroxidation; Male; Rats; Rats, Wistar | 2007 |
Repletion of antioxidant status by EGCG and retardation of oxidative damage induced macromolecular anomalies in aged rats.
Topics: Aging; Animals; Antioxidants; Catechin; Drug Evaluation, Preclinical; Lipid Peroxidation; Liver; Male; Muscle, Skeletal; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Sulfhydryl Compounds | 2008 |
Protective effect of (-)-epigallocatechin-gallate (EGCG) on lipid peroxide metabolism in isoproterenol induced myocardial infarction in male Wistar rats: a histopathological study.
Topics: Animals; Catechin; Isoproterenol; Lipid Peroxidation; Male; Myocardial Infarction; Myocardium; Rats; Rats, Wistar | 2008 |
Green tea polyphenol epigallocatechin-3-gallate signaling pathway through 67-kDa laminin receptor.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Flavonoids; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Melanoma, Experimental; Mice; Myosin-Light-Chain Phosphatase; Peptide Elongation Factor 1; Phenols; Phosphorylation; Polyphenols; Receptors, Laminin; Signal Transduction | 2008 |
Influence of epigallocatechin gallate and phenolic compounds from green tea on the growth of Oenococcus oeni.
Topics: Antioxidants; Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Culture Media; Dose-Response Relationship, Drug; Food Microbiology; Leuconostoc; Manganese; Phenols; Plant Extracts; Spectrophotometry, Atomic; Staining and Labeling; Wine | 2008 |
Fyn is a novel target of (-)-epigallocatechin gallate in the inhibition of JB6 Cl41 cell transformation.
Topics: Activating Transcription Factor 2; Adaptor Proteins, Signal Transducing; Animals; Antioxidants; Catechin; Cell Survival; Cell Transformation, Neoplastic; CREB-Binding Protein; Dose-Response Relationship, Drug; Epidermal Growth Factor; Glutathione Transferase; Kinetics; Mice; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; RNA, Small Interfering; STAT1 Transcription Factor; Time Factors; Transcription Factor AP-1 | 2008 |
Solid-state NMR analysis of the orientation and dynamics of epigallocatechin gallate, a green tea polyphenol, incorporated into lipid bilayers.
Topics: Camellia sinensis; Catechin; Lipid Bilayers; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular | 2008 |
The combination of epigallocatechin gallate and curcumin suppresses ER alpha-breast cancer cell growth in vitro and in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blotting, Western; Breast Neoplasms; Catechin; Cell Division; Cell Line, Tumor; Curcumin; ErbB Receptors; Estrogen Receptor alpha; Female; Flow Cytometry; Humans; Mice; Mice, Nude; Oncogene Protein v-akt; Organ Size; Vascular Endothelial Growth Factor Receptor-1; Weight Gain | 2008 |
Epigallocatechin-3-gallate inhibits interleukin-1beta-induced MUC5AC gene expression and MUC5AC secretion in normal human nasal epithelial cells.
Topics: Catechin; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression; Humans; Interleukin-1beta; Lung Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mucin 5AC; Mucins; Nasal Mucosa; Promoter Regions, Genetic; Signal Transduction; Tumor Cells, Cultured | 2008 |
EGCG inhibits activation of the insulin-like growth factor (IGF)/IGF-1 receptor axis in human hepatocellular carcinoma cells.
Topics: Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Proliferation; Hepatocytes; Humans; Liver Neoplasms; Phosphorylation; Receptor, IGF Type 1; Signal Transduction | 2008 |
Comparative examination of anti-proliferative activities of (-)-epigallocatechin gallate and (--)-epigallocatechin against HCT116 colorectal carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Catechin; Cell Cycle; Cell Proliferation; HCT116 Cells; Humans; Mitogen-Activated Protein Kinases | 2008 |
Epigallocatechin-3-gallate induces apoptosis and cell cycle arrest in HTLV-1-positive and -negative leukemia cells.
Topics: Apoptosis; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Human T-lymphotropic virus 1; Humans; Leukemia-Lymphoma, Adult T-Cell; RNA, Messenger; Transforming Growth Factors | 2008 |
Investigation of the mechanism of enhanced effect of EGCG on huperzine A's inhibition of acetylcholinesterase activity in rats by a multispectroscopic method.
Topics: Acetylcholinesterase; Alkaloids; Animals; Catechin; Cholinesterase Inhibitors; Kinetics; Male; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared | 2008 |
Epigallocatechin gallate inactivates clinical isolates of herpes simplex virus.
Topics: Animals; Catechin; Cell Line; Chlorocebus aethiops; Dose-Response Relationship, Drug; Female; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Microscopy, Electron; Vero Cells; Virion; Virus Inactivation | 2008 |
Molecular modelling study of the mechanism of high-potency inhibition of human catechol-O-methyltransferase by (-)-epigallocatechin-3-O-gallate.
Topics: Animals; Catechin; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Kinetics; Methylation; Models, Molecular; Rats; Swine | 2008 |
Absorption and pharmacokinetics of green tea catechins in beagles.
Topics: Administration, Oral; Animals; Antioxidants; Biological Availability; Biotransformation; Catechin; Dogs; Female; Glucuronides; Intestinal Absorption; Models, Animal; Sulfuric Acid Esters; Tea; Time Factors | 2008 |
[Effects of cell growth and apoptosis of preneoplastic Syrian hamster embryo cells by green tea constituent epigallocatechin-3-gallate].
Topics: Animals; Apoptosis; Catechin; Cell Division; Cell Line, Tumor; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Female; Precancerous Conditions; Pregnancy; Tea | 2007 |
N-Acetylcysteine enhances the lung cancer inhibitory effect of epigallocatechin-3-gallate and forms a new adduct.
Topics: Acetylcysteine; Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Flow Cytometry; Humans; Lung Neoplasms; Mice; Radiation-Protective Agents | 2008 |
Effects of epigallocatechin-3-gallate on mitochondrial integrity and antioxidative enzyme activity in the aging process of human fibroblast.
Topics: Antioxidants; Catalase; Catechin; Cellular Senescence; Fibroblasts; Flow Cytometry; Gene Expression; Glutathione Peroxidase; Humans; Mitochondria; Oxidoreductases; Radiation-Protective Agents; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase | 2008 |
Attenuation of senescence-induced oxidative exacerbations in aged rat brain by (-)-epigallocatechin-3-gallate.
Topics: Aging; Animals; Antioxidants; Brain Diseases, Metabolic; Catechin; Cytoprotection; Flavonoids; Lipid Peroxidation; Male; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Phenols; Polyphenols; Rats; Rats, Wistar; Up-Regulation | 2008 |
Antiplatelet activity of epigallocatechin gallate is mediated by the inhibition of PLCgamma2 phosphorylation, elevation of PGD2 production, and maintaining calcium-ATPase activity.
Topics: Animals; Arachidonic Acid; Calcium-Transporting ATPases; Catechin; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Male; Phospholipase C gamma; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin D2; Rabbits; Rats; Rats, Sprague-Dawley; Tea | 2008 |
The application of proteomics for studying the neurorescue activity of the polyphenol (-)-epigallocatechin-3-gallate.
Topics: Catechin; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Flavonoids; Gene Expression; Humans; Neuroblastoma; Phenols; Polyphenols; Proteomics | 2008 |
Mechanism of inhibition of wt-dihydrofolate reductase from E. coli by tea epigallocatechin-gallate.
Topics: Animals; Biosensing Techniques; Catechin; Cattle; Enzymes, Immobilized; Escherichia coli; Folic Acid Antagonists; Humans; Kinetics; Liver; Models, Molecular; Tea; Tetrahydrofolate Dehydrogenase; Thermodynamics | 2008 |
Topical treatment with (-)-epigallocatechin-3-gallate and genistein after a single UV exposure can reduce skin damage.
Topics: Administration, Topical; Animals; Cadherins; Catechin; Genistein; Mice; Mice, Hairless; Radiation-Protective Agents; Skin; Ultraviolet Rays | 2008 |
(-)Epigallocatechin gallate hampers collagen destruction and collagenase activation in ultraviolet-B-irradiated human dermal fibroblasts: involvement of mitogen-activated protein kinase.
Topics: Blotting, Western; Catechin; Cell Survival; Collagen; Collagenases; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Fibroblasts; Humans; Immunohistochemistry; Matrix Metalloproteinases; Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Skin; Ultraviolet Rays | 2008 |
Epigallocatechin-3-gallate inhibits growth of activated hepatic stellate cells by enhancing the capacity of glutathione synthesis.
Topics: Animals; Buthionine Sulfoximine; Catechin; Cell Proliferation; Cytoplasm; Dose-Response Relationship, Drug; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione; Hepatocytes; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Transforming Growth Factor beta1 | 2008 |
n-Hexane toxicity in Jurkat T-cells is mediated by reactive oxygen species.
Topics: Antioxidants; Benzoquinones; Catechin; Cell Proliferation; Dose-Response Relationship, Drug; Hexanes; Humans; Indicators and Reagents; Jurkat Cells; L-Lactate Dehydrogenase; Oxazines; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Solvents; Xanthenes | 2008 |
Differential effects of a green tea-derived polyphenol (-)-epigallocatechin-3-gallate on the acidosis-induced decrease in the Ca(2+) sensitivity of cardiac and skeletal muscle.
Topics: Acidosis; Animals; Antioxidants; Calcium; Catechin; Chickens; Dose-Response Relationship, Drug; Heart; Hydrogen-Ion Concentration; Mice; Muscle, Skeletal; Myocardium; Protein Isoforms; Tea; Troponin C | 2008 |
[Effect of (-)-epigallocatechin-3-gallate and 5-AZA-CdR on expression of X-linked inhibitor of apoptosis protein-associated factor 1 in human leukemia HL-60 and K562 cells].
Topics: Adaptor Proteins, Signal Transducing; Anticarcinogenic Agents; Antimetabolites, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; bcl-2-Associated X Protein; Catechin; Drug Synergism; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Interferon-alpha; Intracellular Signaling Peptides and Proteins; K562 Cells; Neoplasm Proteins; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Up-Regulation; X-Linked Inhibitor of Apoptosis Protein | 2008 |
[Protective effect of epigallocatechin-3-gallate on inflammatory bowel disease: experiment with rat models of induced colitis].
Topics: Animals; Blotting, Western; Catechin; Cyclooxygenase 2; Disease Models, Animal; Gene Expression; Inflammatory Bowel Diseases; Intestinal Mucosa; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trinitrobenzenesulfonic Acid | 2007 |
Subcutaneous injection, from birth, of epigallocatechin-3-gallate, a component of green tea, limits the onset of muscular dystrophy in mdx mice: a quantitative histological, immunohistochemical and electrophysiological study.
Topics: Animals; Camellia sinensis; Catechin; Creatine Kinase; Electrophysiology; Immunohistochemistry; Injections, Subcutaneous; Lipofuscin; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle Contraction; Muscle, Skeletal; Muscular Dystrophy, Duchenne; RNA, Messenger; Utrophin | 2008 |
Epigallocatechin gallate, a constituent of green tea, regulates high glucose-induced apoptosis.
Topics: Antioxidants; Apoptosis; Blotting, Western; Catechin; DNA Damage; DNA Fragmentation; Flow Cytometry; Fluorescent Dyes; Glucose; Glycation End Products, Advanced; Humans; Indoles; Membrane Potentials; Mitochondrial Membranes; Oxidation-Reduction; Tea; U937 Cells | 2008 |
Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat.
Topics: Animals; Anticarcinogenic Agents; beta Catenin; Caffeine; Carcinogens; Catechin; Colonic Neoplasms; Imidazoles; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Rats; Survival Analysis; Tea | 2008 |
Epigallocatechin-3-gallate reduces retinal ischemia/reperfusion injury by attenuating neuronal nitric oxide synthase expression and activity.
Topics: Animals; Antioxidants; Apoptosis; Catechin; Cell Death; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Glial Fibrillary Acidic Protein; In Situ Nick-End Labeling; Lipid Peroxidation; NADP; Neuroprotective Agents; Nitric Oxide Synthase; Rats; Rats, Wistar; Reperfusion Injury; Retinal Diseases; Retinal Ganglion Cells | 2008 |
(-)-Epigallocatechin gallate, a major constituent of green tea, poisons human type II topoisomerases.
Topics: Antigens, Neoplasm; Camellia sinensis; Catechin; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins; Humans; Plant Extracts; Recombinant Proteins; Tea | 2008 |
Preventive effect of (-)epigallocatechin-gallate (EGCG) on lysosomal enzymes in heart and subcellular fractions in isoproterenol-induced myocardial infarcted Wistar rats.
Topics: Animals; Cardiovascular Agents; Catechin; Disease Models, Animal; Heart; Isoproterenol; Lysosomes; Male; Myocardial Infarction; Rats; Rats, Wistar; Subcellular Fractions; Time Factors | 2008 |
Inhibition of intestinal ischemia/repurfusion induced apoptosis and necrosis via down-regulation of the NF-kB, c-Jun and caspace-3 expression by epigallocatechin-3-gallate administration.
Topics: Animals; Apoptosis; Caspase 3; Catechin; Down-Regulation; In Situ Nick-End Labeling; Intestinal Mucosa; Intestines; Ischemia; Male; Malondialdehyde; Microscopy; Necrosis; NF-kappa B; Peroxidase; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; Reperfusion Injury | 2008 |
Green tea extract and its major component epigallocatechin gallate inhibits hepatitis B virus in vitro.
Topics: Antiviral Agents; Catechin; Cell Line, Tumor; DNA, Viral; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Microbial Sensitivity Tests; Plant Extracts; Tea | 2008 |
Diastereomeric difference of inclusion modes between (-)-epicatechin gallate, (-)-epigallocatechin gallate and (+)-gallocatechin gallate, with beta-cyclodextrin in aqueous solvent.
Topics: Catechin; Magnetic Resonance Spectroscopy; Molecular Conformation; Solvents; Stereoisomerism; Water | 2008 |
Free Zn(2+) enhances inhibitory effects of EGCG on the growth of PC-3 cells.
Topics: Antioxidants; Catechin; Cell Division; Cell Line, Tumor; Cell Survival; Humans; Male; Prostatic Neoplasms; Protease Inhibitors; Zinc | 2008 |
Synthesis and biological activity of a 3,4,5-trimethoxybenzoyl ester analogue of epicatechin-3-gallate.
Topics: Antioxidants; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Gene Expression Profiling; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Models, Molecular; Molecular Structure; NADP; RNA, Messenger; Stereoisomerism; Structure-Activity Relationship; Tea; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Time Factors | 2008 |
Epigallocatechin-3-gallate ameliorates rats colitis induced by acetic acid.
Topics: Acetic Acid; Animals; Catechin; Colitis; Cytokines; Indicators and Reagents; Interferon-gamma; Intestinal Mucosa; Male; Malondialdehyde; Nitric Oxide; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2008 |
Antioxidants prevent ethanol-associated apoptosis in fetal rhombencephalic neurons.
Topics: Antioxidants; Apoptosis; Benzimidazoles; Catechin; Cells, Cultured; Central Nervous System Depressants; Curcumin; Ethanol; Fluorescent Dyes; Melatonin; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Resveratrol; Rhombencephalon; Signal Transduction; Stilbenes; Thioctic Acid | 2008 |
Epigallocatechin gallate protects against oxidative stress-induced mitochondria-dependent apoptosis in human lens epithelial cells.
Topics: Apoptosis; Caspase Inhibitors; Catechin; Cell Line; Cytochromes c; Cytosol; Enzyme Activation; Epithelial Cells; Humans; Hydrogen Peroxide; Lens, Crystalline; Membrane Potential, Mitochondrial; Mitochondria; Mitogen-Activated Protein Kinases; Oxidative Stress; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species | 2008 |
[DNA-protective potential of polyphenols in human mucosa cell cultures].
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Carcinogens; Catechin; Cells, Cultured; DNA Damage; Dose-Response Relationship, Drug; Flavonoids; Humans; Mouth Mucosa; Phenols; Polyphenols; Tannins | 2008 |
Effects of epigallocatechin-3-gallate (EGCG) on in vitro maturation and fertilization of porcine oocytes.
Topics: Acrosome Reaction; Animals; Antioxidants; Catechin; Female; Fertilization in Vitro; Hydrogen Peroxide; Male; Oocytes; Oogenesis; Pregnancy; Pregnancy Rate; Sperm Capacitation; Swine | 2008 |
Protein phosphatase 1 activation and alternative splicing of Bcl-X and Mcl-1 by EGCG + ibuprofen.
Topics: Alternative Splicing; bcl-X Protein; Catechin; Cell Line, Tumor; Drug Synergism; Enzyme Activation; Gene Expression Regulation; Humans; Ibuprofen; Male; Myeloid Cell Leukemia Sequence 1 Protein; Prostatic Neoplasms; Protein Phosphatase 1; Proto-Oncogene Proteins c-bcl-2 | 2008 |
Effect of green tea and (-)-epigallocatechin gallate on ethanol-induced toxicity in HepG2 cells.
Topics: Acetylcysteine; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Ethanol; gamma-Glutamyltransferase; Glutathione; Humans; Liver Neoplasms; Plant Extracts; Tea | 2008 |
Antisense experiments demonstrate an exon 4 minus splice variant mRNA as the basis for expression of tNOX, a cancer-specific cell surface protein.
Topics: Alternative Splicing; Anticarcinogenic Agents; Apoptosis; Catechin; Exons; Gene Expression; Gene Expression Regulation; HeLa Cells; Humans; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Oligonucleotides, Antisense; Polymerase Chain Reaction; RNA, Messenger; Transfection | 2007 |
[Effect of epigallocatechin-3-gallate on the invasiveness of hepatocarcinoma cells in vitro].
Topics: Carcinoma, Hepatocellular; Catechin; Cell Adhesion; Cell Survival; Hep G2 Cells; Humans; Liver Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mucin-1; Neoplasm Invasiveness; Plant Extracts | 2007 |
The impact of the 67kDa laminin receptor on both cell-surface binding and anti-allergic action of tea catechins.
Topics: Anti-Allergic Agents; Basophils; Catechin; Cell Line, Tumor; Glycosylation; Histamine Release; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Molecular Structure; Receptors, Laminin; Structure-Activity Relationship; Tea | 2008 |
Investigations of the cytotoxicity of epigallocatechin-3-gallate against PC-3 cells in the presence of Cd2+ in vitro.
Topics: Adenosine Triphosphate; Anticarcinogenic Agents; Apoptosis; Cadmium; Caspase 9; Catechin; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Synergism; Humans; Male; Membrane Potential, Mitochondrial; Prostatic Neoplasms; Receptors, Laminin; Tea; Up-Regulation | 2008 |
Reaction kinetics of degradation and epimerization of epigallocatechin gallate (EGCG) in aqueous system over a wide temperature range.
Topics: Catechin; Drug Stability; Health Promotion; Hot Temperature; Kinetics; Models, Theoretical; Tea; Temperature; Thermodynamics; Water | 2008 |
Simultaneous determination of catechins, rutin, and gallic acid in Cistus species extracts by HPLC with diode array detection.
Topics: Catechin; Chromatography, High Pressure Liquid; Cistus; Gallic Acid; Plant Extracts; Rutin | 2008 |
Characteristics of catechin- and theaflavin-mediated cardioprotection.
Topics: Animals; Animals, Newborn; Antioxidants; Biflavonoids; Cardiotonic Agents; Catechin; Cells, Cultured; Gallic Acid; Hydrogen Peroxide; Myocytes, Cardiac; Oxidants; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Signal Transduction; Tea | 2008 |
CFU-megakaryocytic progenitors expanded ex vivo from cord blood maintain their in vitro homing potential and express matrix metalloproteinases.
Topics: Antigens, CD34; Catechin; Cell Proliferation; Cell Survival; Chemokine CXCL12; Chemotactic Factors; Chemotaxis; Collagen; Colony-Forming Units Assay; Drug Combinations; Fetal Blood; Humans; Interleukin-3; Kinetics; Laminin; Matrix Metalloproteinase 14; Matrix Metalloproteinase 9; Megakaryocytes; Platelet Membrane Glycoprotein IIb; Proteoglycans; Receptors, CXCR4; Stem Cells; Thrombopoietin; Up-Regulation | 2008 |
The combination of raloxifene and epigallocatechin gallate suppresses growth and induces apoptosis in MDA-MB-231 cells.
Topics: Apoptosis; Blotting, Western; Catechin; Cell Cycle; Cell Line, Tumor; Culture Media; ErbB Receptors; Female; Flow Cytometry; Glucuronosyltransferase; Humans; Neuroprotective Agents; Phosphorylation; Proto-Oncogene Proteins c-akt; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators | 2008 |
EGCG reducing the susceptibility to cholesterol gallstone formation through the regulation of inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Cholecystitis; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Disease Susceptibility; Female; Gallstones; Gene Expression Profiling; Lipid Peroxidation; Lipids; Liver; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis | 2008 |
The beneficial effect of (-)-epigallocatechin-3-gallate in an experimental model of Alzheimer's disease in rat: a behavioral analysis.
Topics: Alzheimer Disease; Animals; Catechin; Disease Models, Animal; Male; Maze Learning; Psychomotor Performance; Rats; Rats, Wistar | 2007 |
Epigallocatechin-3-O-gallate inhibits TNFalpha-induced monocyte chemotactic protein-1 production from vascular endothelial cells.
Topics: Animals; Catechin; Cattle; Cell Line; Chemokine CCL2; Chromones; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Morpholines; Oncogene Protein v-akt; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Tea; Tumor Necrosis Factor-alpha | 2008 |
Potential anthelmintics: polyphenols from the tea plant Camellia sinensis L. are lethally toxic to Caenorhabditis elegans.
Topics: Animals; Antinematodal Agents; Caenorhabditis elegans; Camellia sinensis; Catechin; Flavonoids; Phenols; Plant Extracts; Plant Leaves; Polyphenols; Tea | 2008 |
Positive inotropic effects of epigallocatechin-3-gallate (EGCG) involve activation of Na+/H+ and Na+/Ca2+ exchangers.
Topics: Animals; Cardiotonic Agents; Catechin; Male; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Rats; Rats, Wistar; Signal Transduction; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers | 2008 |
(-)-Epigallocatechin gallate reduces transforming growth factor beta-stimulated HSP27 induction through the suppression of stress-activated protein kinase/c-Jun N-terminal kinase in osteoblasts.
Topics: Animals; Animals, Newborn; Antioxidants; Blotting, Western; Catechin; Cell Line; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; JNK Mitogen-Activated Protein Kinases; Mice; Osteoblasts; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Tea; Transforming Growth Factor beta | 2008 |
[Molecular mechanism by which green tea and tea extract inhibits left ventricle hypertrophy induced by renovascular hypertension in rats].
Topics: Animals; Antioxidants; Catechin; Flavonoids; Hypertension, Renovascular; Hypertrophy, Left Ventricular; Male; Phenols; Polyphenols; Random Allocation; Rats; Rats, Wistar; Tea | 2008 |
Involvement of 67-kDa laminin receptor-mediated myosin phosphatase activation in antiproliferative effect of epigallocatechin-3-O-gallate at a physiological concentration on Caco-2 colon cancer cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Caco-2 Cells; Catechin; Cell Cycle; Cell Proliferation; Colonic Neoplasms; HeLa Cells; Humans; Myosin-Light-Chain Phosphatase; Phosphorylation; Receptors, Laminin | 2008 |
(-)-Epigallocatechin gallate induces Nrf2-mediated antioxidant enzyme expression via activation of PI3K and ERK in human mammary epithelial cells.
Topics: Antioxidants; Catechin; Cell Line; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Enzymologic; Glutamate-Cysteine Ligase; Heme Oxygenase (Decyclizing); Humans; Mammary Glands, Human; NF-E2-Related Factor 2; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Superoxide Dismutase | 2008 |
Epigallocatechin-3-gallate (EGCG) inhibits the migratory behavior of tumor bronchial epithelial cells.
Topics: Antineoplastic Agents, Phytogenic; Bronchial Neoplasms; Catechin; Cell Culture Techniques; Cell Death; Cell Line, Tumor; Cell Movement; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Epithelial Cells; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Imaging, Three-Dimensional; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Microscopy, Video; Neoplasm Invasiveness; Protease Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Vimentin | 2008 |
Biochanin A inhibits breast cancer tumor growth in a murine xenograft model.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Genistein; Humans; Injections, Intraperitoneal; Liver; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Quercetin; Time Factors; Xenograft Model Antitumor Assays | 2008 |
Interaction of dicaffeoylquinic derivatives with peroxynitrite and other reactive nitrogen species.
Topics: Animals; Bicarbonates; Catechin; Cattle; Fibroblasts; Humans; Inhibitory Concentration 50; Lipopolysaccharides; Macrophages; Mice; Neutrophils; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Oxidation-Reduction; Peroxynitrous Acid; Quinic Acid; Reactive Nitrogen Species; Serum Albumin, Bovine; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tyrosine | 2008 |
Effects of (-) -epigallocatechin gallate in liver of an animal model of combined (physical and mental) fatigue.
Topics: Animals; Catechin; Dose-Response Relationship, Drug; Fatigue; Injections, Intraperitoneal; Liver; Male; Models, Animal; Random Allocation; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Time Factors | 2008 |
(-)Epigallocatechin-gallate (EGCG) prevents mitochondrial damage in isoproterenol-induced cardiac toxicity in albino Wistar rats: a transmission electron microscopic and in vitro study.
Topics: Animals; Antioxidants; Catalase; Catechin; Free Radical Scavengers; Glutathione; In Vitro Techniques; Isoproterenol; Lipid Peroxides; Male; Microscopy, Electron, Transmission; Mitochondria, Heart; Myocardial Infarction; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2008 |
Green tea epigallocatechin-3-gallate (EGCG) reduces beta-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Catechin; Cognition Disorders; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Maze Learning; Mice; Mice, Transgenic; Mutation; Neuroprotective Agents; Phosphorylation; tau Proteins | 2008 |
Effects of water-soluble natural antioxidants on photosensitized oxidation of conjugated linoleic acid in an oil-in-water emulsion system.
Topics: Antioxidants; Ascorbic Acid; Catechin; Emulsions; Flavonoids; Fruit; Furans; Light; Linoleic Acids, Conjugated; Oxidation-Reduction; Phenols; Polyphenols; Singlet Oxygen; Solubility; Vitis; Water | 2008 |
Green tea polyphenol epigallocatechin-3-gallate suppresses collagen production and proliferation in keloid fibroblasts via inhibition of the STAT3-signaling pathway.
Topics: Animals; Catechin; Cell Cycle; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen; Fibroblasts; Flavonoids; Humans; Keloid; Mice; Mice, Nude; Mitogen-Activated Protein Kinase Kinases; Phenols; Phosphatidylinositol 3-Kinases; Polyphenols; Protein Kinase Inhibitors; RNA, Small Interfering; Signal Transduction; STAT3 Transcription Factor; Tea; Triterpenes; Wound Healing | 2008 |
The modulation of endothelial cell gene expression by green tea polyphenol-EGCG.
Topics: Catechin; Cell Proliferation; Cells, Cultured; Endothelial Cells; Flavonoids; Gene Expression Profiling; Gene Expression Regulation; Humans; Phenols; Polyphenols; Tea; Vascular Endothelial Growth Factors | 2008 |
Green tea polyphenols affect skin preservation in rats and improve the rate of skin grafts.
Topics: Animals; Animals, Genetically Modified; Catechin; Flavonoids; Graft Survival; Male; Mice; Mice, Nude; Organ Preservation; Phenols; Polyphenols; Rats; Rats, Sprague-Dawley; Skin Transplantation; Tea | 2008 |
Epigallocatechin gallate improves serum lipid profile and erythrocyte and cardiac tissue antioxidant parameters in Wistar rats fed an atherogenic diet.
Topics: Animals; Anticholesteremic Agents; Antioxidants; Aorta, Thoracic; Ascorbic Acid; Atherosclerosis; Camellia sinensis; Catalase; Catechin; Diet, Atherogenic; Erythrocytes; Glutathione Peroxidase; Hypercholesterolemia; Injections, Intraperitoneal; Lipid Peroxidation; Lipids; Male; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Superoxide Dismutase; Vitamin E | 2008 |
Hypoxia-stimulated vascular endothelial growth factor production in human nasal polyp fibroblasts: effect of epigallocatechin-3-gallate on hypoxia-inducible factor-1 alpha synthesis.
Topics: Antioxidants; Camellia sinensis; Catechin; Cell Hypoxia; Cells, Cultured; Cobalt; Fibroblasts; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Nasal Polyps; Neovascularization, Pathologic; Plant Extracts; Vascular Endothelial Growth Factor A | 2008 |
Epigallocatechin-3-gallate suppresses TNF-alpha -induced production of MMP-1 and -3 in rheumatoid arthritis synovial fibroblasts.
Topics: Antioxidants; Arthritis, Rheumatoid; Catechin; Cells, Cultured; Dose-Response Relationship, Drug; Drug Antagonism; Fibroblasts; Gene Expression; Gene Expression Regulation, Enzymologic; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Mitogen-Activated Protein Kinases; RNA, Messenger; Synovial Membrane; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2008 |
Epigallocatechin gallate (EGCG) attenuates high glucose-induced insulin signaling blockade in human hepG2 hepatoma cells.
Topics: Adaptor Proteins, Signal Transducing; Adenylate Kinase; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Glucose; Humans; Insulin Receptor Substrate Proteins; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-akt; Signal Transduction | 2008 |
Effects of Epigallocatechin-3-gallate on lead-induced oxidative damage.
Topics: Animals; Animals, Newborn; Antioxidants; Catechin; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Antagonism; Female; Glutathione; Hippocampus; Injections, Intraperitoneal; Lactation; Lipid Peroxidation; Long-Term Potentiation; Malondialdehyde; Maternal Exposure; Membrane Potential, Mitochondrial; Neurons; Organometallic Compounds; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase | 2008 |
(-)-Epigallocatechin gallate inhibits basic fibroblast growth factor-stimulated interleukin-6 synthesis in osteoblasts.
Topics: Animals; Anthracenes; Catechin; Cells, Cultured; Fibroblast Growth Factor 2; Interleukin-6; Mice; Mitogen-Activated Protein Kinase 3; Organic Chemicals; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation | 2008 |
Orally administered epigallocatechin gallate attenuates light-induced photoreceptor damage.
Topics: Administration, Oral; Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Catechin; Glial Fibrillary Acidic Protein; Light; Membrane Potentials; Neuroglia; Oxidative Stress; Photoreceptor Cells; Rats; Rats, Wistar; Retina; Retinal Degeneration; Rhodopsin; RNA, Messenger | 2008 |
EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers.
Topics: alpha-Synuclein; Amyloid; Amyloid beta-Peptides; Amyloid Neuropathies; Catechin; Humans; Peptide Fragments; Plaque, Amyloid; Protein Binding | 2008 |
Protein phosphatase-2A is a target of epigallocatechin-3-gallate and modulates p53-Bak apoptotic pathway.
Topics: Animals; Apoptosis; Base Sequence; bcl-2 Homologous Antagonist-Killer Protein; Blotting, Western; Catechin; Cell Line; Chromatin Immunoprecipitation; DNA Primers; Flow Cytometry; Immunohistochemistry; Mice; Phosphorylation; Protein Phosphatase 2; Tumor Suppressor Protein p53 | 2008 |
Escaping amyloid fate.
Topics: alpha-Synuclein; Amyloid beta-Peptides; Amyloid Neuropathies; Catechin; Humans; Peptide Fragments; Plaque, Amyloid | 2008 |
(-)Epigallocatechingallate protects the mitochondria against the deleterious effects of lipids, calcium and adenosine triphosphate in isoproterenol induced myocardial infarcted male Wistar rats.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Calcium; Catechin; Cholesterol; Fatty Acids, Nonesterified; Isoproterenol; Lipid Peroxides; Lipids; Male; Mitochondria, Heart; Myocardial Infarction; Phospholipids; Protective Agents; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Thiobarbituric Acid Reactive Substances; Triglycerides | 2008 |
Green tea catechin enhances cholesterol 7alpha-hydroxylase gene expression in HepG2 cells.
Topics: Analysis of Variance; Camellia sinensis; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cholesterol 7-alpha-Hydroxylase; Dose-Response Relationship, Drug; Gene Expression; Humans; Liver; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Tea | 2008 |
Effects of (-)-epigallocatechin gallate on the redox reactions of human hemoglobin.
Topics: Aspirin; Catechin; Cross-Linking Reagents; Hemoglobins; Humans; Oxidation-Reduction | 2008 |
Studies on the interaction of copper complexes of (-)-epicatechin gallate and (-)-epigallocatechin gallate with calf thymus DNA.
Topics: Animals; Catechin; Cattle; Circular Dichroism; Copper; DNA; Molecular Structure; Organometallic Compounds; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2008 |
Synergistic effect of green tea polyphenols on their protection against FK506-induced cytotoxicity in renal cells.
Topics: Animals; Apoptosis; Beverages; Caspase 3; Catechin; Cell Line; Cell Survival; Drug Synergism; Flavonoids; Immunosuppressive Agents; Kidney Tubules, Proximal; Phenols; Polyphenols; Reactive Oxygen Species; Swine; Tacrolimus | 2008 |
Antioxidant effects of green tea and its polyphenols on bladder cells.
Topics: Antioxidants; Apoptosis; Camellia sinensis; Catechin; Cell Line; Cells, Cultured; Flavonoids; Humans; Hydrogen Peroxide; Oxidants; Oxidative Stress; Phenols; Plant Extracts; Polyphenols; Reactive Oxygen Species; Signal Transduction; Urinary Bladder; Urothelium | 2008 |
Synergistic inhibition of head and neck tumor growth by green tea (-)-epigallocatechin-3-gallate and EGFR tyrosine kinase inhibitor.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Cell Proliferation; Disease Progression; Drug Synergism; Enzyme Inhibitors; ErbB Receptors; Erlotinib Hydrochloride; Flow Cytometry; Fluorescent Antibody Technique; Head and Neck Neoplasms; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Nude; Protein-Tyrosine Kinases; Quinazolines; Transplantation, Heterologous | 2008 |
Enhanced anti-influenza A virus activity of (-)-epigallocatechin-3-O-gallate fatty acid monoester derivatives: effect of alkyl chain length.
Topics: Animals; Antiviral Agents; Catalysis; Catechin; Chemistry, Pharmaceutical; Detergents; Dogs; Drug Design; Fatty Acids; Flavonoids; Influenza A Virus, H1N1 Subtype; Models, Chemical; Phenols; Polyphenols; Solubility; Water | 2008 |
A green tea component suppresses posttranslational expression of basic fibroblast growth factor in colorectal cancer.
Topics: Acetylcysteine; Adenomatous Polyposis Coli; Animals; Antineoplastic Agents, Phytogenic; Camellia sinensis; Catechin; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cycloheximide; Cysteine Proteinase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Fibroblast Growth Factor 2; Genes, APC; HCT116 Cells; HT29 Cells; Humans; Mice; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Time Factors; Transfection | 2008 |
Inhibition of invasion and up-regulation of E-cadherin expression in human malignant melanoma cell line A375 by (-)-epigallocatechin-3-gallate.
Topics: Blotting, Western; Cadherins; Catechin; Cell Adhesion; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Neoplasm Invasiveness; Neoplasm Metastasis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin Neoplasms; Time Factors; Up-Regulation | 2008 |
The nitration of platelet vasodilator stimulated phosphoprotein following exposure to low concentrations of hydrogen peroxide.
Topics: Blood Platelets; Catechin; Cell Adhesion Molecules; Humans; Hydrogen Peroxide; Microfilament Proteins; Nitrates; Nitric Oxide; Phosphoproteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Processing, Post-Translational | 2008 |
(-)-Epigallocatechin-3-gallate suppresses osteoclast differentiation and ameliorates experimental arthritis in mice.
Topics: Animals; Antimutagenic Agents; Arthritis; Blotting, Western; Catechin; Cell Differentiation; Disease Models, Animal; Down-Regulation; Gene Expression; Humans; Mice; NF-kappa B; NFATC Transcription Factors; Osteoclasts; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
Food-drug interaction of (-)-epigallocatechin-3-gallate on the pharmacokinetics of irinotecan and the metabolite SN-38.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Area Under Curve; Bile; Biological Transport; Camptothecin; Catechin; Chromatography, High Pressure Liquid; Contraindications; Dietary Supplements; Food-Drug Interactions; Glucuronides; Injections, Intravenous; Irinotecan; Male; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms | 2008 |
The sensitization of glioma cells to cisplatin and tamoxifen by the use of catechin.
Topics: Antineoplastic Agents; Catechin; Cell Death; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Glioma; Humans; Tamoxifen; Telomerase | 2009 |
Effect of a prodrug of the green tea polyphenol (-)-epigallocatechin-3-gallate on the growth of androgen-independent prostate cancer in vivo.
Topics: Acetates; Androgens; Animals; Apoptosis; Biological Availability; Catechin; Cell Division; Humans; Immunohistochemistry; Ki-67 Antigen; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Prodrugs; Proliferating Cell Nuclear Antigen; Prostate-Specific Antigen; Prostatic Neoplasms; Tea; Transplantation, Heterologous | 2008 |
The antioxidant epigallocatechin gallate (EGCG) moderates the deleterious effects of maternal hyperthermia on follicle-enclosed oocytes in mice.
Topics: Animals; Antioxidants; Blastocyst; Body Temperature; Catechin; Cells, Cultured; Cytoprotection; Embryo Culture Techniques; Embryo, Mammalian; Embryonic Development; Female; Fever; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mothers; Oocytes; Ovarian Follicle; Oxidative Stress | 2008 |
(-)-Epigallocatechin gallate causes internalization of the epidermal growth factor receptor in human colon cancer cells.
Topics: Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Colonic Neoplasms; Endosomes; Epidermal Growth Factor; ErbB Receptors; Humans; Phosphorylation; Ubiquitin | 2008 |
[Protection and its mechanism of catechin morphon on hypoxia-reoxygenation [corrected] induced injury in myocardial cells].
Topics: Animals; Cardiotonic Agents; Catechin; Female; Free Radicals; Hypoxia; Myocytes, Cardiac; Oxygen; Protein Kinase C; Proteins; Rats; Signal Transduction; Survival Rate | 2008 |
Enhancement of antioxidant defense system by epigallocatechin-3-gallate during bleomycin induced experimental pulmonary fibrosis.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Ascorbic Acid; Bleomycin; Body Weight; Catechin; Glutathione; Injections, Intraperitoneal; Lung; Male; Organ Size; Pulmonary Fibrosis; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Vitamin E | 2008 |
Teatime. Drink to your health.
Topics: Antioxidants; Camellia sinensis; Catechin; Health Promotion; Humans; Tea | 2008 |
Regulating the age-related oxidative damage, mitochondrial integrity, and antioxidative enzyme activity in Fischer 344 rats by supplementation of the antioxidant epigallocatechin-3-gallate.
Topics: Aging; Animals; Antioxidants; Body Weight; Catalase; Catechin; Dietary Supplements; DNA, Mitochondrial; Eating; Glutathione Peroxidase; Kidney; Liver; Male; Membrane Potential, Mitochondrial; Mitochondria; Oligonucleotide Array Sequence Analysis; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Inbred F344; Superoxide Dismutase | 2008 |
Epigallocatechin-3-gallate improves Dermatophagoides pteronissinus extract-induced atopic dermatitis-like skin lesions in NC/Nga mice by suppressing macrophage migration inhibitory factor.
Topics: Animals; Antigens, Dermatophagoides; Catechin; Cytokines; Dermatitis, Atopic; Ear, External; Enzyme-Linked Immunosorbent Assay; Female; Immunohistochemistry; Immunosuppressive Agents; Macrophage Migration-Inhibitory Factors; Mice; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin; Tacrolimus | 2008 |
Epigallocatechin-3-gallate inhibits estrogen-induced activation of endometrial cells in vitro and causes regression of endometriotic lesions in vivo.
Topics: Angiogenesis Inhibitors; Animals; Catechin; Cell Line; Cell Proliferation; Cricetinae; Endometriosis; Endometrium; Estradiol; Female; Gene Expression; Ovarian Follicle; Vascular Endothelial Growth Factor A | 2008 |
Epigallocatechin-3-gallate suppressed the over-expression of HSP 70 and MDR1 induced by heat shock in SGC 7901.
Topics: Anticarcinogenic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Catechin; Cell Line, Tumor; Cell Proliferation; Hot Temperature; HSP70 Heat-Shock Proteins; Humans; RNA, Messenger | 2008 |
Comparison of delphinidin, quercetin and (-)-epigallocatechin-3-gallate as inhibitors of the EGFR and the ErbB2 receptor phosphorylation.
Topics: Anthocyanins; Carcinoma; Catechin; Cell Line, Tumor; ErbB Receptors; Female; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Quercetin; Receptor, ErbB-2; Vulvar Neoplasms | 2008 |
Epigallocatechin gallate inhibits endothelial exocytosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Catechin; Cell Line, Tumor; Endothelial Cells; Exocytosis; Humans; Leukocytes; Nitric Oxide; Thrombin; Weibel-Palade Bodies | 2008 |
(-)-Epigallocatechin-3-gallate (EGCG) inhibits HGF-induced invasion and metastasis in hypopharyngeal carcinoma cells.
Topics: Base Sequence; Blotting, Western; Catechin; Cell Line, Tumor; Cell Proliferation; DNA Primers; Enzyme Induction; Hepatocyte Growth Factor; Humans; Hypopharyngeal Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasm Metastasis; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
Chemoprevention of dibenzo[a,l]pyrene transplacental carcinogenesis in mice born to mothers administered green tea: primary role of caffeine.
Topics: Animals; Anticarcinogenic Agents; Benzopyrenes; Caffeine; Carcinogens; Catechin; Chemoprevention; Female; Maternal-Fetal Exchange; Mice; Neoplasms; Placenta; Plant Extracts; Pregnancy; Tea | 2008 |
Aggregation of a proline-rich protein induced by epigallocatechin gallate and condensed tannins: effect of protein glycosylation.
Topics: Catechin; Colloids; Drug Stability; Glycosylation; Humans; Light; Proanthocyanidins; Proline; Salivary Proteins and Peptides; Scattering, Radiation; Seeds; Solutions; Vitis; X-Rays | 2008 |
[Inhibitory effect of tea polyphenols and EGCG on cultured hypertrophic myocyte induced by Ang II].
Topics: Angiotensin II; Animals; Animals, Newborn; Cardiomegaly; Catechin; Cells, Cultured; Female; Flavonoids; Male; Myocytes, Cardiac; Phenols; Polyphenols; Rats; Rats, Wistar; Tea | 2008 |
Tea polyphenols can restrict benzo[a]pyrene-induced lung carcinogenesis by altered expression of p53-associated genes and H-ras, c-myc and cyclin D1.
Topics: Animals; Apoptosis; Benzo(a)pyrene; Biflavonoids; Catechin; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin D1; Female; Flavonoids; Lung; Lung Neoplasms; Male; Mice; Phenols; Polyphenols; Proto-Oncogene Proteins c-myc; ras Proteins; Tea; Tumor Suppressor Protein p53 | 2009 |
Role of caveolin-1 in EGCG-mediated protection against linoleic-acid-induced endothelial cell activation.
Topics: Catechin; Caveolin 1; Cell Line; Cyclooxygenase 2; Down-Regulation; Endothelium, Vascular; Humans; Linoleic Acid; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Up-Regulation | 2009 |
The protective effects of N-acetyl-L-cysteine and epigallocatechin-3-gallate on electric field-induced hepatic oxidative stress.
Topics: Acetylcysteine; Animals; Catechin; Electromagnetic Fields; Glutathione Peroxidase; Guinea Pigs; Lipid Peroxidation; Liver; Male; Nitric Oxide; Oxidative Stress; Peroxidase; Radiation-Protective Agents | 2008 |
Plant polyphenols mobilize nuclear copper in human peripheral lymphocytes leading to oxidatively generated DNA breakage: implications for an anticancer mechanism.
Topics: Antineoplastic Agents; Catechin; Cell Nucleus; Cell Survival; Cells, Cultured; Comet Assay; DNA Breaks; Flavonoids; Humans; Hydrogen Peroxide; Lymphocytes; Oxidants; Oxidation-Reduction; Oxidative Stress; Phenanthrolines; Phenols; Plant Extracts; Polyphenols | 2008 |
Effects of green tea polyphenol on methylation status of RECK gene and cancer cell invasion in oral squamous cell carcinoma cells.
Topics: Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Cell Movement; DNA Methylation; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Membrane Glycoproteins; Mouth Neoplasms; Neoplasm Invasiveness; Polymerase Chain Reaction; Promoter Regions, Genetic; RNA, Messenger; RNA, Neoplasm; Tea | 2008 |
Green tea intake, MTHFR/TYMS genotype and breast cancer risk: the Singapore Chinese Health Study.
Topics: Aged; Breast Neoplasms; Case-Control Studies; Catechin; Female; Folic Acid; Folic Acid Antagonists; Genotype; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Risk Factors; Tea; Thymidylate Synthase | 2008 |
(-)-Epigallocatechin 3-O-gallate (EGCG)-induced apoptosis in normal rat kidney interstitial fibroblast (NRK-49F) cells.
Topics: Animals; Apoptosis; Caspase 3; Catechin; Cell Proliferation; Cells, Cultured; Fibroblasts; Kidney; Rats | 2008 |
Novel and potent inhibitors of fatty acid synthase derived from catechins and their inhibition on MCF-7 cells.
Topics: Breast Neoplasms; Catechin; Cell Line, Tumor; Enzyme Inhibitors; Fatty Acid Synthases; Female; Humans; Hydrochloric Acid; Inhibitory Concentration 50; Kinetics; Propionates; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfuric Acids | 2009 |
Molecular dynamics study on the biophysical interactions of seven green tea catechins with lipid bilayers of cell membranes.
Topics: Biophysical Phenomena; Biophysics; Catechin; Cell Membrane; Chemical Phenomena; Chemistry, Physical; Lipid Bilayers; Models, Molecular; Molecular Structure; Static Electricity; Tea | 2008 |
Effect of genistein on the bioavailability and intestinal cancer chemopreventive activity of (-)-epigallocatechin-3-gallate.
Topics: Animals; Anticarcinogenic Agents; Biological Availability; Catechin; Drug Interactions; Genistein; HT29 Cells; Humans; Intestinal Neoplasms; Male; Mice | 2008 |
A high-throughput reporter gene assay to prove the ability of natural compounds to modulate glutathione peroxidase, superoxide dismutase and catalase gene promoters in V79 cells.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Carcinogens; Carnitine; Catalase; Catechin; Cells, Cultured; Chromans; Cricetinae; Cricetulus; Genistein; Glutathione Peroxidase; Herbicides; Humans; Luciferases; Paraquat; Promoter Regions, Genetic; Quercetin; Rats; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Vitamin B Complex | 2008 |
Selective effects of tea extract and its phenolic compounds on human peripheral blood mononuclear cell cytokine secretions.
Topics: Antioxidants; Caffeine; Camellia sinensis; Catechin; Cytokines; Gallic Acid; Humans; Interferon-gamma; Interleukin-1beta; Interleukin-6; Leukocytes, Mononuclear; Phenols; Plant Extracts; Tea; Tumor Necrosis Factor-alpha | 2009 |
New phenolic components and chromatographic profiles of green and fermented teas.
Topics: Biflavonoids; Catechin; Chromatography, High Pressure Liquid; Fermentation; Flavonoids; Glycosylation; Phenols; Spectrometry, Mass, Electrospray Ionization; Tea | 2008 |
(-)-Epigallocatechin gallate regulates CD3-mediated T cell receptor signaling in leukemia through the inhibition of ZAP-70 kinase.
Topics: Apoptosis; Catechin; CD3 Complex; Cell Line, Tumor; Gene Expression Regulation, Leukemic; Humans; Interleukin-2; Jurkat Cells; Leukemia; Models, Biological; Molecular Conformation; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; ZAP-70 Protein-Tyrosine Kinase | 2008 |
Green tea reduces LDL oxidability and improves vascular function.
Topics: Adult; Antigen-Antibody Complex; Brachial Artery; Camellia sinensis; Catechin; Cholesterol; Female; Humans; Lipid Peroxidation; Lipoproteins, LDL; Plant Extracts; Tea; Triglycerides; Vasodilation | 2008 |
Green tea extracts interfere with the stress-protective activity of PrP and the formation of PrP.
Topics: Animals; Antioxidants; Catechin; Cell Death; Cell Line, Tumor; Drugs, Chinese Herbal; Endocytosis; Flavonoids; Humans; Lysosomes; Mice; Molecular Structure; Oxidative Stress; Phenols; Polyphenols; Prion Diseases; Protein Conformation; PrPC Proteins; PrPSc Proteins; Signal Transduction; Solubility | 2008 |
EGCG inhibits mammary cancer cell migration through inhibition of nitric oxide synthase and guanylate cyclase.
Topics: Animals; Anticarcinogenic Agents; Carcinoma; Catechin; Cell Line, Tumor; Cell Movement; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Mammary Neoplasms, Animal; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrogen Oxides; Oxadiazoles; Quinoxalines | 2008 |
Antiproliferative and apoptosis-inducing activities of alkyl gallate and gallamide derivatives related to (-)-epigallocatechin gallate.
Topics: Amides; Apoptosis; Caspase 12; Catechin; Cell Proliferation; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Gallic Acid; HL-60 Cells; Humans; Molecular Structure; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Stereoisomerism; Structure-Activity Relationship; Transcription Factor CHOP; Tumor Cells, Cultured | 2008 |
Epigallocatechin-3-gallate and curcumin suppress amyloid beta-induced beta-site APP cleaving enzyme-1 upregulation.
Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Antioxidants; Aspartic Acid Endopeptidases; Blotting, Western; Catechin; Cells, Cultured; Cerebral Cortex; Curcumin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Mice; Oxidative Stress; Peptide Fragments; Rats; Reactive Oxygen Species; Up-Regulation | 2008 |
Effects of EGCG on voltage-gated sodium channels in primary cultures of rat hippocampal CA1 neurons.
Topics: Animals; Animals, Newborn; Catechin; Cells, Cultured; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Electrophysiology; Hippocampus; Ion Channel Gating; Neurons; Patch-Clamp Techniques; Rats; Sodium Channel Agonists; Sodium Channel Blockers; Sodium Channels | 2008 |
Massive accumulation of gallic acid and unique occurrence of myricetin, quercetin, and kaempferol in preparing old oolong tea.
Topics: Camellia sinensis; Catechin; Desiccation; Flavonoids; Gallic Acid; Kaempferols; Plant Leaves; Quercetin; Tea; Time Factors | 2008 |
Stress chaperone GRP78/BiP confers chemoresistance to tumor-associated endothelial cells.
Topics: Antineoplastic Agents; Brain Neoplasms; Caspases; Catechin; Cell Death; Drug Resistance, Neoplasm; Endoplasmic Reticulum Chaperone BiP; Endothelial Cells; Heat-Shock Proteins; Humans; Molecular Chaperones; Protein Folding; RNA, Small Interfering | 2008 |
Bioactive dietary polyphenolic compounds reduce nonheme iron transport across human intestinal cell monolayers.
Topics: Antioxidants; Biological Transport; Caco-2 Cells; Catechin; Chelating Agents; Epithelial Cells; Humans; Intestinal Mucosa; Intestines; Iron; Oxidation-Reduction; Plant Extracts; Seeds; Vitis | 2008 |
The major green tea polyphenol, (-)-epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice.
Topics: Adipose Tissue; Animals; Biomarkers; Body Weight; Catechin; Diet; Dietary Fats; Eating; Fatty Liver; Feces; Lipids; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Obesity; Tea | 2008 |
EGCG stabilizes p27kip1 in E2-stimulated MCF-7 cells through down-regulation of the Skp2 protein.
Topics: Blotting, Western; Catechin; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p27; Down-Regulation; Estrogens; Flow Cytometry; Gene Expression Regulation, Neoplastic; Guanine Nucleotide Exchange Factors; Humans; Immunoblotting; Immunoprecipitation; Models, Biological; Nuclear Proteins; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; S-Phase Kinase-Associated Proteins | 2008 |
Green tea polyphenol (-)-epigallocatechin gallate reduces neuronal cell damage and up-regulation of MMP-9 activity in hippocampal CA1 and CA2 areas following transient global cerebral ischemia.
Topics: Animals; Catechin; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Flavonoids; Hippocampus; Immunohistochemistry; In Situ Nick-End Labeling; Ischemic Attack, Transient; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Phenols; Polyphenols; Tea; Up-Regulation | 2009 |
Green tea epigallocatechin 3-gallate accumulates in mitochondria and displays a selective antiapoptotic effect against inducers of mitochondrial oxidative stress in neurons.
Topics: Animals; Apoptosis; Catechin; Immunohistochemistry; Mitochondria; Neurons; Oxidative Stress; Rats; Rats, Sprague-Dawley; Tea | 2009 |
Imidazolium salts: a mild reducing and antioxidative reagent.
Topics: Acetylcysteine; Animals; Antioxidants; Catechin; Dose-Response Relationship, Drug; Gold; Hepatic Stellate Cells; Imidazolines; Metal Nanoparticles; Oxidative Stress; Rats; Reactive Oxygen Species; Reducing Agents | 2008 |
Endoplasmic reticulum stress underlying the pro-apoptotic effect of epigallocatechin gallate in mouse hepatoma cells.
Topics: alpha-Glucosidases; Animals; Antineoplastic Agents; Apoptosis; Calcium; Catechin; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Eukaryotic Initiation Factor-2; Fluorescent Antibody Technique; Glucosides; Glycoside Hydrolase Inhibitors; Hymecromone; Liver Neoplasms, Experimental; Mice; Phosphorylation; Protein Folding; Stress, Physiological; Time Factors; Transcription Factor CHOP | 2009 |
Covalent modification of proteins by green tea polyphenol (-)-epigallocatechin-3-gallate through autoxidation.
Topics: Antineoplastic Agents; Antioxidants; Binding Sites; Catechin; Cell Survival; Cysteine; Drug Screening Assays, Antitumor; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Molecular Conformation; Oxidation-Reduction; Tea; Tumor Cells, Cultured | 2008 |
Polyphenol-induced dissociation of various amyloid fibrils results in a methionine-independent formation of ROS.
Topics: Amyloid; Catechin; Curcumin; Flavonoids; Humans; In Vitro Techniques; Islet Amyloid Polypeptide; Kinetics; Methionine; Models, Biological; Peroxides; Phenols; Polyphenols; Protein Binding; Reactive Oxygen Species; Time Factors | 2008 |
Protective effects of epigallocatechin gallate after UV irradiation of cultured human lens epithelial cells.
Topics: Antioxidants; Catechin; Cell Count; Cell Survival; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Lens, Crystalline; Radiation Injuries; Radiation-Protective Agents; Tetrazolium Salts; Thiazoles; Ultraviolet Rays | 2008 |
Epigallocatechin-3-gallate inhibits IL-6 synthesis and suppresses transsignaling by enhancing soluble gp130 production.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Catechin; Cells, Cultured; Cytokine Receptor gp130; Cytokines; Disease Models, Animal; Female; Fibroblasts; Gene Expression Regulation; Humans; Interleukin-1beta; Interleukin-6; Matrix Metalloproteinase 2; Rats; Rats, Inbred Lew; Receptors, Interleukin-6; Synovial Membrane; Up-Regulation | 2008 |
A new role for tamoxifen in oestrogen receptor-negative breast cancer when it is combined with epigallocatechin gallate.
Topics: Animals; Antineoplastic Agents, Hormonal; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Breast Neoplasms; Catechin; Cell Line, Tumor; Cytochrome P-450 CYP1B1; Down-Regulation; Drug Therapy, Combination; ErbB Receptors; Female; Humans; Mice; Mice, Nude; Protein Kinases; Receptors, Estrogen; Tamoxifen; TOR Serine-Threonine Kinases; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2008 |
Epigallocatechin gallate stimulates glucose uptake through the phosphatidylinositol 3-kinase-mediated pathway in L6 rat skeletal muscle cells.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Catechin; Cells, Cultured; Glucose; Hypoglycemic Agents; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphorylation; Rats | 2008 |
Effects of oral consumption of the green tea polyphenol EGCG in a murine model for human Sjogren's syndrome, an autoimmune disease.
Topics: Administration, Oral; Animals; Antibodies, Antinuclear; Apoptosis; Catechin; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Humans; Ki-67 Antigen; Lymphocytes; Mice; Mice, Inbred NOD; Phytotherapy; Proliferating Cell Nuclear Antigen; Sjogren's Syndrome; Submandibular Gland; Tea | 2008 |
Suppression of cell proliferation and gene expression by combinatorial synergy of EGCG, resveratrol and gamma-tocotrienol in estrogen receptor-positive MCF-7 breast cancer cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Chromans; Dose-Response Relationship, Drug; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Mice; Models, Biological; Resveratrol; Stilbenes; Superoxide Dismutase; Vitamin E | 2008 |
Epigallocatechin-3-gallate diminishes CCL2 expression in human osteoblastic cells via up-regulation of phosphatidylinositol 3-Kinase/Akt/Raf-1 interaction: a potential therapeutic benefit for arthritis.
Topics: Animals; Antioxidants; Arthritis, Experimental; Arthritis, Rheumatoid; Catechin; Cells, Cultured; Chemokine CCL2; Down-Regulation; Humans; Male; Oncogene Protein v-akt; Osteoblasts; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-raf; Rats; Signal Transduction | 2008 |
Inhibition of gap junctional intercellular communication by the green tea polyphenol (-)-epigallocatechin gallate in normal rat liver epithelial cells.
Topics: Animals; Catechin; Cell Communication; Cells, Cultured; Connexin 43; Epithelial Cells; Flavonoids; Gap Junctions; Mitogen-Activated Protein Kinase 3; Phenols; Phosphorylation; Polyphenols; Rats; Tea | 2008 |
Inhibition of pectin methyl esterase activity by green tea catechins.
Topics: Camellia sinensis; Carboxylic Ester Hydrolases; Catechin; Citrus; Fluorometry; Plant Extracts; Solanum lycopersicum; Substrate Specificity; Tea | 2008 |
The anti-inflammatory and anti-cancer properties of epigallocatechin-3-gallate are mediated by folate cycle disruption, adenosine release and NF-kappaB suppression.
Topics: Adenosine; Anticarcinogenic Agents; Antioxidants; Caco-2 Cells; Catechin; Colonic Neoplasms; Folic Acid; Humans; I-kappa B Proteins; Leucovorin; NF-kappa B; NF-KappaB Inhibitor alpha; Proto-Oncogene Proteins c-akt; Tumor Necrosis Factor-alpha; Vitamin B Complex | 2008 |
"Do you want a vodka? No, a green tea please!" Epigallocatechin gallate and its possible role in oxidative stress and liver damage.
Topics: Animals; Beverages; Camellia sinensis; Catechin; Free Radical Scavengers; Humans; Liver; Oxidative Stress; Tea | 2009 |
Screening of DHFR-binding drugs by MALDI-TOFMS.
Topics: Antineoplastic Agents; Catechin; Drug Evaluation, Preclinical; Enzyme Inhibitors; Folic Acid Antagonists; Protein Binding; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tea; Tetrahydrofolate Dehydrogenase | 2008 |
Epigallocatechin gallate promotes GLUT4 translocation in skeletal muscle.
Topics: Androstadienes; Animals; Camellia sinensis; Catechin; Genistein; Glucose; Glucose Transporter Type 4; Insulin; Insulin Resistance; Mice; Mice, Inbred C57BL; Muscle Fibers, Skeletal; Muscle, Skeletal; Protein Transport; Rats; Rats, Sprague-Dawley; Wortmannin | 2008 |
Protective role of tea catechins on erythrocytes subjected to oxidative stress during human aging.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Antioxidants; Catechin; Cells, Cultured; Erythrocyte Membrane; Erythrocytes; Female; Glutathione; Humans; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Sulfhydryl Compounds; Tea; tert-Butylhydroperoxide; Young Adult | 2009 |
[Impact of epigallocatechin gallate on gene expression profiles of human hepatocellular carcinoma cell lines BEL7404/ADM and BEL7402/5-FU].
Topics: Anticarcinogenic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cyclin G1; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Profiling; Humans; Liver Neoplasms; Oligonucleotide Array Sequence Analysis; Vault Ribonucleoprotein Particles | 2008 |
Simultaneous determination of the major active components of tea polyphenols in rat plasma by a simple and specific HPLC assay.
Topics: Animals; Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Flavonoids; Injections, Intravenous; Linear Models; Male; Phenols; Polyphenols; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Resorcinols; Sensitivity and Specificity; Tea | 2008 |
[Demethylation and transcription of p16 gene in malignant lymphoma cell line CA46 induced by EGCG].
Topics: Catechin; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Gene Expression Regulation, Neoplastic; Genes, p16; Humans; Lymphoma; Transcription, Genetic | 2008 |
Pathogenesis of ganglion "cell death" in glaucoma and neuroprotection: focus on ganglion cell axonal mitochondria.
Topics: Antioxidants; Axons; Catechin; Cell Death; Creatine; Glaucoma; Humans; Mitochondria; Neuroprotective Agents; Niacinamide; Optic Disk; Retinal Ganglion Cells; Thioctic Acid; Vitamin B Complex | 2008 |
Epigalocatechin-3-gallate (EGCG) downregulates PEA15 and thereby augments TRAIL-mediated apoptosis in malignant glioma.
Topics: Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Caspase 7; Catechin; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glioma; Humans; Inhibitor of Apoptosis Proteins; Intracellular Signaling Peptides and Proteins; Microtubule-Associated Proteins; Phosphoproteins; Survivin; TNF-Related Apoptosis-Inducing Ligand | 2008 |
Time-dependent intracellular trafficking of FITC-conjugated epigallocatechin-3-O-gallate in L-929 cells.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Nucleus; Cells, Cultured; Cytoplasm; Fibroblasts; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Mice; Microscopy, Confocal; Tea; Time Factors | 2008 |
Structural identification of novel glucoside and glucuronide metabolites of (-)-epigallocatechin-3-gallate in mouse urine using liquid chromatography/electrospray ionization tandem mass spectrometry.
Topics: Animals; Catechin; Chromatography, Liquid; Glucosides; Glucuronides; Male; Mice; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2008 |
Protection of brain and pancreas from high-fat diet: effects of catechin and caffeine.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Animals; Body Weight; Brain; Caffeine; Catechin; Central Nervous System Stimulants; Deoxyguanosine; Dietary Fats; Eating; Female; Glucose Tolerance Test; Lipid Metabolism; Maze Learning; Mice; Mice, Mutant Strains; Pancreas; Sesquiterpenes; Synaptophysin; Time Factors | 2009 |
Suppression of androgen receptor signaling and prostate specific antigen expression by (-)-epigallocatechin-3-gallate in different progression stages of LNCaP prostate cancer cells.
Topics: Animals; Catechin; Cell Line, Tumor; Cell Proliferation; Disease Progression; Humans; Male; Mice; Mice, Inbred BALB C; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Recurrence; Signal Transduction; Transcription, Genetic | 2009 |
Absorption, metabolism and excretion of Choladi green tea flavan-3-ols by humans.
Topics: Catechin; Chromatography, High Pressure Liquid; Flavonoids; Humans; Intestinal Absorption; Spectrometry, Mass, Electrospray Ionization; Tea | 2009 |
Enhanced antitumor activities of (-)-epigallocatechin-3-O-gallate fatty acid monoester derivatives in vitro and in vivo.
Topics: Acylation; Animals; Antineoplastic Agents; Catechin; Cell Line, Tumor; Cell Proliferation; Fatty Acids; Humans; Inhibitory Concentration 50; Mice; Mice, Inbred BALB C; Molecular Structure; Rats; Rats, Sprague-Dawley; Xenograft Model Antitumor Assays | 2008 |
Epigallocatechin gallate is a slow-tight binding inhibitor of enoyl-ACP reductase from Plasmodium falciparum.
Topics: Animals; Antimalarials; Catechin; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Plasmodium falciparum; Triclosan | 2008 |
(-)-Epigallocatechin-3-gallate prevents lipopolysaccharide-induced elevation of beta-amyloid generation and memory deficiency.
Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Apoptosis; Avoidance Learning; Brain; Catechin; Cerebral Cortex; Cyclooxygenase 2; Glial Fibrillary Acidic Protein; Hippocampus; Lipopolysaccharides; Male; Maze Learning; Memory; Memory Disorders; Mice; Nerve Tissue Proteins; Neurons; Nitric Oxide Synthase Type II; Peptide Fragments | 2009 |
PCR differential display-based identification of regulator of G protein signaling 10 as the target gene in human colon cancer cells induced by black tea polyphenol theaflavin monogallate.
Topics: Biflavonoids; Caco-2 Cells; Catechin; Colonic Neoplasms; Enzyme Induction; Flavonoids; Gallic Acid; Gene Expression Regulation; Humans; Phenols; Polyphenols; RGS Proteins; Tea; Time Factors | 2008 |
Microchip reversed-phase liquid chromatography with packed column and electrochemical flow cell using polystyrene/poly(dimethylsiloxane).
Topics: Catechin; Chromatography, Liquid; Dimethylpolysiloxanes; Electrochemistry; Electrodes; Equipment Design; Lab-On-A-Chip Devices; Microchip Analytical Procedures; Particle Size; Polystyrenes; Sensitivity and Specificity | 2008 |
(-)-Epigallocatechin-3-gallate potentiates the cytotoxicity induced by benzyl isothiocyanate and hydrogen peroxide in human Jurkat T lymphocytes.
Topics: Apoptosis; Catechin; Humans; Hydrogen Peroxide; Isothiocyanates; Jurkat Cells; Mitogen-Activated Protein Kinases; Signal Transduction; T-Lymphocytes | 2008 |
Inhibitory effect of green tea extract and (-)-epigallocatechin-3-gallate on mammalian thioredoxin reductase and HeLa cell viability.
Topics: Animals; Catechin; Cattle; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Inhibitory Concentration 50; Kinetics; Models, Chemical; NADP; Tea; Thioredoxin-Disulfide Reductase; Thioredoxins | 2008 |
In vitro cytotoxicity of (-)-EGCG octaacetate on MDAMB-231 and SKHep-1 human carcinoma cells: a pharmacological consideration on prodrug design.
Topics: Acetates; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Proliferation; Drug Design; Humans; Prodrugs | 2008 |
[Neuroprotective effect of epigallocatechin gallate on oxidative-stress-injured retinal cells].
Topics: Animals; Apoptosis; Catechin; Cell Survival; Cells, Cultured; Hydrogen Peroxide; In Situ Nick-End Labeling; Neuroprotective Agents; Oxidative Stress; Rats; Reactive Oxygen Species; Retinal Ganglion Cells; Tea | 2008 |
(-)-Epigallocatechin gallate/gelatin layer-by-layer assembled films and microcapsules.
Topics: Adsorption; Antioxidants; Capsules; Catechin; Drug Delivery Systems; Electrochemistry; Electrophoresis; Gelatin; Membranes, Artificial; Permeability | 2009 |
Antioxidants alleviate electric field-induced effects on lung tissue based on assays of heme oxygenase-1, protein carbonyl content, malondialdehyde, nitric oxide, and hydroxyproline.
Topics: Acetylcysteine; Animals; Antioxidants; Biodiversity; Catechin; Electromagnetic Fields; Guinea Pigs; Heme Oxygenase-1; Hydroxyproline; Lung Diseases; Male; Malondialdehyde; Nitric Oxide; Protein Carbonylation; Random Allocation | 2009 |
Green tea extract selectively activates peroxisome proliferator-activated receptor beta/delta in cultured cardiomyocytes.
Topics: Animals; Animals, Newborn; Antioxidants; Catechin; Cell Hypoxia; Cells, Cultured; Enzyme Activation; Myocytes, Cardiac; Nitric Oxide; Plant Extracts; PPAR delta; PPAR-beta; Rats; Rats, Wistar; Tea | 2009 |
Significant longevity-extending effects of EGCG on Caenorhabditis elegans under stress.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Camellia sinensis; Catechin; Cell Culture Techniques; Cell Survival; Cellular Senescence; DNA-Binding Proteins; Forkhead Transcription Factors; Gene Expression Regulation; Heat-Shock Proteins; Microscopy, Fluorescence; Organisms, Genetically Modified; Oxidative Stress; Superoxide Dismutase; Transcription Factors | 2009 |
The effects of green tea (-)-epigallocatechin-3-gallate on reactive oxygen species in 3T3-L1 preadipocytes and adipocytes depend on the glutathione and 67 kDa laminin receptor pathways.
Topics: 3T3-L1 Cells; Acetylcysteine; Adipocytes; Animals; Antibodies; Catechin; Glutathione; Mice; Reactive Oxygen Species; Receptors, Laminin; Tea | 2009 |
Can drinking tea prevent cancer? A controversy revisited.
Topics: Anticarcinogenic Agents; Catechin; Flavonoids; Humans; Neoplasms; Phenols; Polyphenols; Tea | 2009 |
[Epigallocatechin-3-gallate induces apoptosis in human hepatocellular carcinoma cells].
Topics: Apoptosis; bcl-X Protein; Carcinoma, Hepatocellular; Caspase 3; Caspase 9; Catechin; Cell Line, Tumor; Cyclooxygenase 2; Humans; Liver Neoplasms; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
Combinatorial effect of epigallocatechin-3-gallate and TRAIL on pancreatic cancer cell death.
Topics: Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 8; Caspase 9; Catechin; Cell Line, Tumor; Enzyme Activation; Fas-Associated Death Domain Protein; Humans; Immunoblotting; Pancreatic Neoplasms; Protease Inhibitors; Ribonucleases; TNF-Related Apoptosis-Inducing Ligand; Tumor Stem Cell Assay | 2009 |
Chemoprevention of fibroid tumors by [-]-epigallocatechin-3-gallate in quail.
Topics: Animals; Anticarcinogenic Agents; Bird Diseases; Catechin; Coturnix; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Leiomyoma; Oviducts; Random Allocation; Uterine Neoplasms | 2008 |
Epigallocatechin gallate from green tea (Camellia sinensis) increases lifespan and stress resistance in Caenorhabditis elegans.
Topics: Animals; Antioxidants; Caenorhabditis; Caenorhabditis elegans Proteins; Camellia sinensis; Catechin; Free Radical Scavengers; Genes, Reporter; Heat-Shock Proteins; Hydrogen Peroxide; Longevity; Oxidative Stress; Plant Extracts; Superoxides; Tea | 2009 |
NMR spectroscopic characterization of inclusion complexes comprising cyclodextrins and gallated catechins in aqueous solution: cavity size dependency.
Topics: Catechin; Computer Simulation; Deuterium Oxide; gamma-Cyclodextrins; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Molecular Conformation; Particle Size; Quantum Theory; Solutions; Stereoisomerism; Thermodynamics | 2009 |
EGCG inhibits proliferation of cardiac fibroblasts in rats with cardiac hypertrophy.
Topics: Angiotensin II; Animals; Antioxidants; Atrial Natriuretic Factor; Camellia sinensis; Cardiomegaly; Catechin; Cell Proliferation; Disease Models, Animal; DNA-Binding Proteins; Dose-Response Relationship, Drug; Endothelins; Enzyme Inhibitors; Fibroblasts; Fibrosis; Hydroxyproline; Male; Myocardium; Nitric Oxide Synthase Type II; Nitrites; Organ Size; Plant Extracts; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Transcription Factors | 2009 |
Green and black tea are equally potent stimuli of NO production and vasodilation: new insights into tea ingredients involved.
Topics: Animals; Aorta; Beverages; Brain; Catechin; Cattle; Endothelium, Vascular; Humans; Hydrocortisone; Nitric Oxide; Nitric Oxide Synthase Type III; Tea; Tissue Extracts; Vasodilation | 2009 |
Multifunctional effect of epigallocatechin-3-gallate (EGCG) in downregulation of gelatinase-A (MMP-2) in human breast cancer cell line MCF-7.
Topics: Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Female; Fibronectins; Focal Adhesion Kinase 1; Humans; Integrins; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; NF-kappa B; Vitronectin | 2009 |
Inhibitory effects of green tea catechin on the lipid accumulation in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Catechin; Lipolysis; Mice; RNA, Messenger; Tea | 2009 |
Effects of (-) epigallocatechin-3-gallate on Na(+) currents in rat dorsal root ganglion neurons.
Topics: Analgesics, Non-Narcotic; Animals; Antioxidants; Camellia sinensis; Catechin; Cells, Cultured; Dose-Response Relationship, Drug; Ganglia, Spinal; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Channels; Tetrodotoxin | 2009 |
(-)-Epigallocatechin-3-gallate is a novel Hsp90 inhibitor.
Topics: Animals; Binding Sites; Catechin; Cell Line, Tumor; Chickens; Dimerization; Dose-Response Relationship, Drug; Glutathione Transferase; HSP90 Heat-Shock Proteins; Humans; Ligands; Mice; Models, Biological; Molecular Chaperones; Peptide Mapping; Plasmids; Protein Binding; Protein Conformation; Receptors, Aryl Hydrocarbon; Recombinant Fusion Proteins; Response Elements; Tea; Time Factors; Transcription, Genetic | 2009 |
Protective effects of (-)-epigallocatechin gallate on UVA-induced damage in ARPE19 cells.
Topics: Adult; Catechin; Cell Death; Cell Line; Cell Survival; Cyclooxygenase 2; Cytoprotection; DNA Damage; Enzyme Activation; Humans; Hydrogen Peroxide; Intracellular Space; Mitogen-Activated Protein Kinases; Phosphorylation; Protective Agents; Retinal Pigment Epithelium; Ultraviolet Rays | 2008 |
Neuroprotective effects of (-)-epigallocatechin-3-gallate on aging mice induced by D-galactose.
Topics: Aging; Animals; Apoptosis; Caspase 3; Catechin; Female; Galactose; Glutathione Peroxidase; Hippocampus; In Situ Nick-End Labeling; Male; Malondialdehyde; Maze Learning; Mice; Motor Activity; Neuroprotective Agents; Superoxide Dismutase; Time Factors | 2009 |
(-)-Epigallocatechin-3-gallate induces up-regulation of Th1 and Th2 cytokine genes in Jurkat T cells.
Topics: Base Sequence; Catechin; Cytokines; DNA Primers; Humans; Hydrogen Peroxide; Interferon-gamma; Interleukin-13; Interleukin-2; Interleukin-5; Jurkat Cells; MAP Kinase Signaling System; Models, Immunological; RNA, Messenger; Th1 Cells; Th2 Cells; Up-Regulation | 2009 |
[Growth inhibition of prostate cancer cells by epigallocatechin-3-gallate in the presence of Zn2+ in vitro].
Topics: Catechin; Cell Line, Tumor; Cell Movement; Humans; Immunohistochemistry; Male; Matrix Metalloproteinase 9; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Zinc | 2008 |
Epigallocatechin-3-gallate augments antioxidant activities and inhibits inflammation during bleomycin-induced experimental pulmonary fibrosis through Nrf2-Keap1 signaling.
Topics: Animals; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antioxidants; Bleomycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Catechin; Collagen; Fluorescent Antibody Technique; Immunohistochemistry; Interleukin-1beta; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Lung; Male; Mast Cells; Microscopy, Confocal; Proteins; Pulmonary Fibrosis; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction | 2009 |
(-)-Epigallocatechin gallate suppresses azoxymethane-induced colonic premalignant lesions in male C57BL/KsJ-db/db mice.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinoma; Catechin; Cholesterol; Colonic Neoplasms; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Insulin; Intestinal Mucosa; Leptin; Male; Mice; Mice, Inbred C57BL; Precancerous Conditions; Receptor, IGF Type 1; Triglycerides | 2008 |
[Epigallocatechin-3-gallate inhibits growth and angiogenesis of gastric cancer and its molecular mechanism].
Topics: Animals; Catechin; Cell Line, Tumor; Female; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Signal Transduction; STAT3 Transcription Factor; Stomach Neoplasms; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2009 |
Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation.
Topics: Acetylation; Animals; B-Lymphocytes; Catechin; Cell Line, Tumor; Cell Transformation, Viral; Down-Regulation; HeLa Cells; Herpesvirus 4, Human; Histone Acetyltransferases; Humans; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2009 |
(-)-Epigallocatechin gallate reduces platelet-derived growth factor-BB-stimulated interleukin-6 synthesis in osteoblasts: suppression of SAPK/JNK.
Topics: Animals; Becaplermin; Blotting, Western; Catechin; Cell Line; Cells, Cultured; Interleukin-6; Mice; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Osteoblasts; Osteocalcin; Osteoprotegerin; Phosphorylation; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2008 |
(-)-Epigallocatechin gallate inhibition of osteoclastic differentiation via NF-kappaB.
Topics: Active Transport, Cell Nucleus; Animals; Catechin; Cell Differentiation; Cell Line; Mice; NF-kappa B; Osteoclasts; RANK Ligand; Transcription, Genetic | 2009 |
Trapping effects of green and black tea extracts on peroxidation-derived carbonyl substances of seal blubber oil.
Topics: Acrolein; Adipose Tissue; Aldehydes; Animals; Antioxidants; Caniformia; Catechin; Fatty Acids, Omega-3; Gas Chromatography-Mass Spectrometry; Lipid Peroxidation; Oils; Plant Extracts; Tea | 2009 |
A potential proliferative gene, NUDT6, is down-regulated by green tea catechins at the posttranscriptional level.
Topics: 3' Untranslated Regions; Anticarcinogenic Agents; Catechin; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Half-Life; Humans; Oligonucleotide Array Sequence Analysis; p38 Mitogen-Activated Protein Kinases; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Stability; RNA, Messenger; Tea; Time Factors | 2010 |
An extract of green tea, epigallocatechin-3-gallate, reduces periapical lesions by inhibiting cysteine-rich 61 expression in osteoblasts.
Topics: Alveolar Bone Loss; Animals; Antioxidants; Catechin; Cell Line, Tumor; Chemokine CCL2; Chemotaxis, Leukocyte; Cysteine-Rich Protein 61; Disease Models, Animal; Humans; Oncostatin M; Osteoblasts; Periapical Periodontitis; Plant Extracts; Rats; Rats, Wistar; Tea | 2009 |
Green tea (-)-epigallocatechin-3-gallate down-regulates VASP expression and inhibits breast cancer cell migration and invasion by attenuating Rac1 activity.
Topics: Animals; Breast Neoplasms; Catechin; Cell Adhesion Molecules; Cell Line, Tumor; Cell Movement; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Mice; Microfilament Proteins; Neuropeptides; Phosphoproteins; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; RNA, Messenger; RNA, Small Interfering; Tea; Time Factors; Up-Regulation | 2009 |
Green tea (-)-epigallocatechin gallate inhibits insulin stimulation of 3T3-L1 preadipocyte mitogenesis via the 67-kDa laminin receptor pathway.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Obesity Agents; Camellia sinensis; Catechin; Cell Proliferation; Dose-Response Relationship, Drug; Immune Sera; Insulin; Insulin Receptor Substrate Proteins; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Proto-Oncogene Proteins c-raf; Receptors, Laminin; Signal Transduction; Time Factors | 2009 |
Structure-activity relationship of bis-galloyl derivatives related to (-)-epigallocatechin gallate.
Topics: Anticarcinogenic Agents; Caspase 3; Catechin; Cell Proliferation; Cell Survival; Chromatography, Thin Layer; Enzyme Activation; HL-60 Cells; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Structure-Activity Relationship; Tea | 2009 |
Interaction of polyphenols with proteins: binding of (-)-epigallocatechin gallate to serum albumin, estimated by induced circular dichroism.
Topics: Animals; Binding Sites; Catechin; Cattle; Circular Dichroism; Flavonoids; Humans; Indicators and Reagents; Phenols; Polyphenols; Protein Binding; Proteins; Serum Albumin; Serum Albumin, Bovine | 2009 |
Preparation and antioxidant activity of green tea extract enriched in epigallocatechin (EGC) and epigallocatechin gallate (EGCG).
Topics: Antioxidants; Caffeine; Camellia sinensis; Catechin; Food, Fortified; Plant Extracts; Temperature; Time Factors | 2009 |
Interaction of tea catechin (-)-epigallocatechin gallate with lipid bilayers.
Topics: Animals; Calorimetry; Catechin; Cell Membrane; Chickens; Curcumin; Lipid Bilayers; Magainins; Octoxynol; Porosity; Solubility; Tea; Unilamellar Liposomes; X-Ray Diffraction | 2009 |
Green tea polyphenols down-regulate caveolin-1 expression via ERK1/2 and p38MAPK in endothelial cells.
Topics: Animals; Catechin; Cattle; Caveolin 1; Down-Regulation; Endothelium, Vascular; Flavonoids; Imidazoles; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 3; Nitric Oxide Synthase Type III; p38 Mitogen-Activated Protein Kinases; Pyridines; RNA, Messenger; Tea | 2009 |
Preservation of porcine hepatocytes in three-dimensional bioreactor at room temperature using epigallocatechin-3-gallate.
Topics: Animals; Bioreactors; Catechin; Cell Culture Techniques; Cell Proliferation; Cell Survival; Cells, Cultured; Equipment Design; Equipment Failure Analysis; Hepatocytes; Liver, Artificial; Swine; Swine, Miniature; Temperature; Tissue Engineering; Tissue Preservation | 2009 |
Catechin, green tea component, causes caspase-independent necrosis-like cell death in chronic myelogenous leukemia.
Topics: Anticarcinogenic Agents; Apoptosis; Blotting, Western; Caspases; Catechin; Cell Line, Tumor; Cell Proliferation; Humans; Immunoenzyme Techniques; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Membrane Potential, Mitochondrial; Necrosis; Subcellular Fractions; Tea | 2009 |
(-)-Epigallocatechin-3-gallate enhances uncoupling protein 2 gene expression in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Catechin; Gene Expression Regulation; Ion Channels; Mice; Mitochondrial Proteins; Promoter Regions, Genetic; RNA, Messenger; Uncoupling Protein 2 | 2009 |
Preclinical development of the green tea catechin, epigallocatechin gallate, as an HIV-1 therapy.
Topics: Antioxidants; Apoptosis; Camellia sinensis; Catechin; CD4-Positive T-Lymphocytes; Cell Proliferation; Cell Survival; Cells, Cultured; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Macrophages | 2009 |
Effects of oral epigallocatechin gallate supplementation on the minimal erythema dose and UV-induced skin damage.
Topics: Administration, Oral; Animals; Antioxidants; Catechin; Dose-Response Relationship, Radiation; Erythema; Female; Radiation-Protective Agents; Radiodermatitis; Rats; Rats, Hairless; Tea; Ultraviolet Rays; Water Loss, Insensible | 2009 |
EGCG inhibits growth and induces apoptosis in renal cell carcinoma through TFPI-2 overexpression.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Carcinoma, Renal Cell; Catechin; Cell Line, Tumor; Flow Cytometry; Gene Expression; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Kidney Neoplasms; Mice; Mice, Nude; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
[Antiviral effect of epigallocatechin gallate (EGCG) on influenza A virus].
Topics: Animals; Antiviral Agents; Catechin; Female; Influenza A virus; Male; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections | 2008 |
(-)-Epigallocatechin-3-Gallate protects SH-SY5Y cells against 6-OHDA-induced cell death through STAT3 activation.
Topics: Adrenergic Agents; Analysis of Variance; Catechin; Cell Death; Cell Differentiation; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Interactions; Humans; Neuroblastoma; Neuroprotective Agents; Oxidopamine; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Thymidine; Time Factors; Tritium; Tyrosine | 2009 |
Epigallocatechin-3-gallate induced primary cultures of rat hippocampal neurons death linked to calcium overload and oxidative stress.
Topics: Animals; Calcium; Catechin; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Hippocampus; Membrane Potentials; Neurons; Oxidative Stress; Rats; Rats, Wistar; Signal Transduction | 2009 |
Introducing nanochemoprevention as a novel approach for cancer control: proof of principle with green tea polyphenol epigallocatechin-3-gallate.
Topics: Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Survival; Chick Embryo; Drug Stability; Humans; Mice; Nanoparticles; Neoplasms, Experimental; Xenograft Model Antitumor Assays | 2009 |
Epigallocatechin-gallate modulates chemotherapy-induced apoptosis in human cholangiocarcinoma cells.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Bile Duct Neoplasms; Blotting, Western; Camellia sinensis; Catechin; Cell Line, Tumor; Cholangiocarcinoma; Cytochromes c; Deoxycytidine; Fluorouracil; Gemcitabine; Humans; Immunohistochemistry; Membrane Potential, Mitochondrial; Mice; Mice, Nude; Mitomycin; Plant Extracts | 2009 |
Effects of oral epigallocatechin gallate on the oral pharmacokinetics of verapamil in rats.
Topics: Administration, Oral; Animals; Antioxidants; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Calcium Channel Blockers; Catechin; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Male; Rats; Rats, Sprague-Dawley; Verapamil | 2009 |
Turmeric and green tea: a recipe for the treatment of B-chronic lymphocytic leukemia.
Topics: Apoptosis; Catechin; Curcuma; Curcumin; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Tea | 2009 |
Curcumin inhibits prosurvival pathways in chronic lymphocytic leukemia B cells and may overcome their stromal protection in combination with EGCG.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Catechin; Cell Survival; Curcumin; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Myeloid Cell Leukemia Sequence 1 Protein; NF-kappa B; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; STAT3 Transcription Factor; Stromal Cells; X-Linked Inhibitor of Apoptosis Protein | 2009 |
[Inhibition of (-)epigallocatechin gallate on dimethylarsinic acid promoting lung tumorigenesis through the induction of oxidative stress in mice].
Topics: Animals; Antineoplastic Agents; Cacodylic Acid; Catechin; Lung Neoplasms; Male; Mice; Oxidative Stress | 2008 |
Green tea polyphenols rescue of brain defects induced by overexpression of DYRK1A.
Topics: Animals; Antioxidants; Brain; Catechin; Dyrk Kinases; Flavonoids; Gene Dosage; Humans; Memory; Mice; Mice, Transgenic; Neuronal Plasticity; Phenols; Polyphenols; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Tea | 2009 |
Epigallocatechin-3-gallate relaxes the isolated bovine ophthalmic artery: involvement of phosphoinositide 3-kinase-Akt-nitric oxide/cGMP signalling pathway.
Topics: Androstadienes; Animals; Catechin; Cattle; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Ophthalmic Artery; Oxadiazoles; Penicillamine; Peptides; Phosphatidylinositols; Proto-Oncogene Proteins c-akt; Quinoxalines; Serotonin; Signal Transduction; Vasodilation; Wortmannin | 2009 |
Polyphenols prevent clinorotation-induced expression of atrogenes in mouse C2C12 skeletal myotubes.
Topics: Animals; Antioxidants; Catechin; Cell Line; Dexamethasone; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glucocorticoids; Mice; Muscle Fibers, Skeletal; Muscle Proteins; Muscle, Skeletal; Oxidative Stress; Phenols; Phosphorylation; Polyphenols; Quercetin; Rotation; SKP Cullin F-Box Protein Ligases; Tripartite Motif Proteins; Ubiquitin-Protein Ligases | 2009 |
Epigallocatechin gallate up-regulation of miR-16 and induction of apoptosis in human cancer cells.
Topics: Anticarcinogenic Agents; Apoptosis; Carcinoma, Hepatocellular; Catechin; DNA Fragmentation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Genes, Reporter; Hep G2 Cells; Humans; Liver Neoplasms; MicroRNAs; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Proto-Oncogene Proteins c-bcl-2; Tea; Up-Regulation | 2010 |
Systematic characterization of the covalent interactions between (-)-epigallocatechin gallate and peptides under physiological conditions by mass spectrometry.
Topics: Arginine; Catechin; Cysteine; Hydrogen-Ion Concentration; Mass Spectrometry; Methionine; Peptides; Sulfhydryl Compounds; Tandem Mass Spectrometry; Temperature | 2009 |
Novel cell culture model for prevention of carcinogenic risk in familial adenomatous polyposis syndrome.
Topics: Adenomatous Polyposis Coli; Animals; Anticarcinogenic Agents; Catechin; Cell Line; Colonic Neoplasms; Eflornithine; Eicosapentaenoic Acid; Genes, APC; Mice; Mice, Inbred C57BL; Mutation | 2009 |
Epigallocatechin-3-gallate attenuates cardiac hypertrophy in hypertensive rats in part by modulation of mitogen-activated protein kinase signals.
Topics: Animals; Antioxidants; Atrial Natriuretic Factor; Catalase; Catechin; Disease Models, Animal; DNA, Mitochondrial; Electron Transport Chain Complex Proteins; Enzyme Activation; Glutathione Peroxidase; Hemodynamics; Hypertension; Hypertrophy, Left Ventricular; Male; Malondialdehyde; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mitochondria, Heart; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Myocardium; Myosin Heavy Chains; Natriuretic Peptide, Brain; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Transcription Factor AP-1 | 2009 |
Regulation of Vascular Endothelial Growth Factor in endometrial tumour cells by resveratrol and EGCG.
Topics: Anticarcinogenic Agents; Catechin; Endometrial Neoplasms; Enzyme-Linked Immunosorbent Assay; Female; Humans; Resveratrol; Stilbenes; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2009 |
Cisplatin-induced hair cell death requires STAT1 and is attenuated by epigallocatechin gallate.
Topics: Animals; Antineoplastic Agents; Catechin; Cell Death; Cisplatin; Hair Cells, Auditory; Interferon-gamma; Mice; Mice, Knockout; Phosphorylation; Saccule and Utricle; Serine; STAT1 Transcription Factor; Tissue Culture Techniques | 2009 |
Polyphenol control of cell spreading on glycoprotein substrata.
Topics: Biocompatible Materials; Catechin; Cell Adhesion; Cell Line; Cell Movement; Coated Materials, Biocompatible; Fibroblasts; Flavonoids; Glycoproteins; Humans; Materials Testing; Mucins; Phenols; Polylysine; Polyphenols; Surface Properties | 2009 |
Mechanism of free Zn(2+) enhancing inhibitory effects of EGCG on the growth of PC-3 cells: interactions with mitochondria.
Topics: Adenosine Triphosphate; Apoptosis; Caspase 9; Catechin; Cell Division; Cell Line, Tumor; Cytochromes c; Drug Synergism; Humans; Male; Membrane Fluidity; Membrane Potential, Mitochondrial; Mitochondria; Prostatic Neoplasms; Zinc | 2009 |
Antipathogenic properties of green tea polyphenol epigallocatechin gallate at concentrations below the MIC against enterohemorrhagic Escherichia coli O157:H7.
Topics: Animals; Biofilms; Caenorhabditis elegans; Catechin; Colony Count, Microbial; Dose-Response Relationship, Drug; Escherichia coli O157; Escherichia coli Proteins; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Microbial Sensitivity Tests; Quorum Sensing; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tea; Virulence | 2009 |
Green tea polyphenols attenuate glial swelling and mitochondrial dysfunction following oxygen-glucose deprivation in cultures.
Topics: Brain Ischemia; Camellia sinensis; Catechin; Cell Line; Cell Size; Flavonoids; Glucose; Membrane Potential, Mitochondrial; Mitochondria; Neuroglia; Nitric Oxide; Oxygen; Phenols; Plant Extracts; Polyphenols; Tea | 2009 |
Green tea polyphenol epigallocatechin-3-gallate inhibits thrombin-induced hepatocellular carcinoma cell invasion and p42/p44-MAPKinase activation.
Topics: Anticarcinogenic Agents; Carcinoma, Hepatocellular; Catechin; Cell Growth Processes; Cell Line, Tumor; Enzyme Activation; Humans; Liver Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Invasiveness; Oligopeptides; Phosphorylation; Receptor, PAR-1; Receptors, Thrombin; Tea; Thrombin | 2009 |
Freeze-drying of mononuclear cells derived from umbilical cord blood followed by colony formation.
Topics: Catechin; Cell Survival; Culture Media; Dose-Response Relationship, Drug; Fetal Blood; Freeze Drying; Humans; Microscopy, Electron, Scanning; Monocytes | 2009 |
(-)Epigallocatechin-3-gallate inhibits the spontaneous firing of rat locus coeruleus neuron.
Topics: Action Potentials; Animals; Antioxidants; Catechin; Dose-Response Relationship, Drug; Drug Administration Schedule; Locus Coeruleus; Male; Neural Inhibition; Neurons; Norepinephrine; Rats; Rats, Sprague-Dawley; Stress, Psychological; Synaptic Transmission | 2009 |
Green tea (-)-epigallocatechin-3-gallate reduces body weight with regulation of multiple genes expression in adipose tissue of diet-induced obese mice.
Topics: Adipogenesis; Adipose Tissue; Animals; Anti-Obesity Agents; Body Weight; Catechin; Dietary Fats; Dose-Response Relationship, Drug; Epididymis; Gene Expression Regulation; Lipid Metabolism; Lipolysis; Liver; Male; Mice; Mice, Inbred C57BL; Obesity; Oxidation-Reduction; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tea; Thermogenesis; Triglycerides | 2009 |
Attenuation of liver ischemia/reperfusion induced apoptosis by epigallocatechin-3-gallate via down-regulation of NF-kappaB and c-Jun expression.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Catechin; Down-Regulation; Immunohistochemistry; In Situ Nick-End Labeling; Ischemia; Liver Diseases; Malondialdehyde; NF-kappa B; Peroxidase; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; Reperfusion Injury | 2010 |
Electrospun zein fibers as carriers to stabilize (-)-epigallocatechin gallate.
Topics: Catechin; Drug Stability; Electricity; Ethanol; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Microscopy, Electron, Scanning; Solutions; Spectroscopy, Fourier Transform Infrared; Tea; Water; Zein | 2009 |
Study of the interactions between a proline-rich protein and a flavan-3-ol by NMR: residual structures in the natively unfolded protein provides anchorage points for the ligands.
Topics: Amino Acid Sequence; Animals; Catechin; Flavonoids; Humans; Ligands; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Proline; Protein Conformation; Protein Folding; Salivary Proline-Rich Proteins; Sequence Alignment | 2009 |
Down-regulation of myeloid cell leukemia 1 by epigallocatechin-3-gallate sensitizes rheumatoid arthritis synovial fibroblasts to tumor necrosis factor alpha-induced apoptosis.
Topics: Anticarcinogenic Agents; Apoptosis; Arthritis, Rheumatoid; Blotting, Western; Caspase 3; Catechin; Cell Survival; Cells, Cultured; Down-Regulation; Fibroblasts; Myeloid Cell Leukemia Sequence 1 Protein; Osteoarthritis; Proto-Oncogene Proteins c-bcl-2; Synovial Membrane; Tumor Necrosis Factor-alpha | 2009 |
Identification of epigallocatechin-3-gallate in green tea polyphenols as a potent inducer of p53-dependent apoptosis in the human lung cancer cell line A549.
Topics: Apoptosis; Caspase 3; Caspase 7; Catechin; Cell Line, Tumor; Cell Survival; Flavonoids; Humans; Luciferases; Lung Neoplasms; Phenols; Polyphenols; Signal Transduction; Tea; Tumor Suppressor Protein p53 | 2009 |
Difference in growth suppression and apoptosis induction of EGCG and EGC on human promyelocytic leukemia HL-60 cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Catechin; Cell Proliferation; Cricetinae; Dose-Response Relationship, Drug; Enzyme Activation; HL-60 Cells; Humans; Inhibitory Concentration 50; Leukemia, Promyelocytic, Acute; Proto-Oncogene Proteins c-bcl-2; Time Factors | 2009 |
(-)-Epigallocatechin gallate induced apoptosis in human adrenal cancer NCI-H295 cells through caspase-dependent and caspase-independent pathway.
Topics: Adrenal Gland Neoplasms; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Calcium; Caspases; Catechin; Endoplasmic Reticulum Chaperone BiP; Flow Cytometry; Humans; Membrane Potential, Mitochondrial; Protease Inhibitors; Tumor Cells, Cultured | 2009 |
Suppression of cytochrome P450 1A1 expression induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mouse hepatoma hepa-1c1c7 cells treated with serum of (-)-epigallocatechin-3-gallate- and green tea extract-administered rats.
Topics: Animals; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Down-Regulation; Gene Expression Regulation, Neoplastic; Male; Mice; Plant Extracts; Polychlorinated Dibenzodioxins; Rats; Tea | 2009 |
Inhibitory effect of (-)-epigallocatechin and (-)-epigallocatechin gallate against heregulin beta1-induced migration/invasion of the MCF-7 breast carcinoma cell line.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Catechin; Cell Cycle; Cell Line, Tumor; Cell Migration Assays; Cell Movement; Cell Survival; Female; Humans; Neoplasm Invasiveness; Neuregulin-1; Phosphorylation; Protein Multimerization; Receptor, ErbB-2; Receptor, ErbB-3 | 2009 |
The green tea polyphenol (-)-epigallocatechin-3-gallate inhibits leukocyte activation by bacterial formylpeptide through the receptor FPR.
Topics: Animals; Antioxidants; Calcium-Calmodulin-Dependent Protein Kinases; Camellia sinensis; Catechin; Cell Line, Tumor; Cell Movement; Flavonoids; Humans; Inflammation; Injections, Intraperitoneal; Leukemia, Basophilic, Acute; Mice; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Rats; Receptors, Formyl Peptide; Signal Transduction; Transfection; Transgenes | 2009 |
Mitochondrial alterations in aging rat brain: effective role of (-)-epigallo catechin gallate.
Topics: Aging; Animals; Antioxidants; Brain; Catechin; Electron Transport Chain Complex Proteins; Lipid Peroxidation; Male; Mitochondria; Neurons; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Rats | 2009 |
Highly antibiotic-resistant Acinetobacter baumannii clinical isolates are killed by the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG).
Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Camellia; Catechin; Drug Resistance, Multiple, Bacterial; Drug Synergism; Humans; Mafenide; Microbial Sensitivity Tests; Microbial Viability | 2009 |
Inhibition of mutagenic PhIP formation by epigallocatechin gallate via scavenging of phenylacetaldehyde.
Topics: Acetaldehyde; Antimutagenic Agents; Catechin; Imidazoles; Mutagens | 2009 |
Albumin stabilizes (-)-epigallocatechin gallate in human serum: binding capacity and antioxidant property.
Topics: Catechin; Drug Stability; Humans; Protein Binding; Serum Albumin; Sulfhydryl Compounds | 2009 |
Free radicals generated during oxidation of green tea polyphenols: electron paramagnetic resonance spectroscopy combined with density functional theory calculations.
Topics: Antioxidants; Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Free Radicals; In Vitro Techniques; Models, Theoretical; Oxidation-Reduction; Oxidative Stress; Plant Extracts; Superoxides; Tea | 2009 |
Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-alpha and matrix metalloproteinase-13 in human chondrocytes.
Topics: Aged; Catechin; Cells, Cultured; Chondrocytes; Female; Flavonoids; Gene Expression Regulation; Glycation End Products, Advanced; Humans; Male; Matrix Metalloproteinase 13; Matrix Metalloproteinase Inhibitors; Middle Aged; Phenols; Polyphenols; Protease Inhibitors; Serum Albumin, Bovine; Tea; Tumor Necrosis Factor-alpha | 2009 |
Catechin-induced activation of the LKB1/AMP-activated protein kinase pathway.
Topics: 3T3-L1 Cells; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Catechin; Cell Differentiation; Enzyme Activation; Humans; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred BALB C; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Signal Transduction | 2009 |
The main green tea polyphenol epigallocatechin-3-gallate counteracts semen-mediated enhancement of HIV infection.
Topics: Amyloid; Anti-HIV Agents; Camellia sinensis; Catechin; Cells, Cultured; HIV Infections; HIV-1; Humans; Male; Peptide Fragments; Protein Tyrosine Phosphatases; Semen | 2009 |
Cell viability of normal human skin fibroblast and fibroblasts derived from granulation tissue: effects of nutraceuticals.
Topics: Analysis of Variance; Antioxidants; Camellia sinensis; Carotenoids; Catechin; Cell Survival; Cells, Cultured; Cholesteatoma, Middle Ear; Dietary Supplements; Dimethyl Sulfoxide; Fibroblasts; Furans; Genistein; Granulation Tissue; Humans; Lycopene; Plant Extracts; Skin; Solvents | 2009 |
Lung cancer inhibitory effect of epigallocatechin-3-gallate is dependent on its presence in a complex mixture (polyphenon E).
Topics: Adenoma; Aerosols; Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Biological Availability; Catechin; Drug Screening Assays, Antitumor; Drug Synergism; Female; Lung Neoplasms; Mice; Mice, Inbred A; Tea | 2009 |
Synergistic growth inhibition of squamous cell carcinoma of the head and neck by erlotinib and epigallocatechin-3-gallate: the role of p53-dependent inhibition of nuclear factor-kappaB.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Squamous Cell; Catechin; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Drug Screening Assays, Antitumor; Drug Synergism; Erlotinib Hydrochloride; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; NF-kappa B; Protein Kinase Inhibitors; Quinazolines; RNA, Small Interfering; Transcription Factor RelA; Tumor Suppressor Protein p53 | 2009 |
Chinese green tea ameliorates lung injury in cigarette smoke-exposed rats.
Topics: Animals; Antioxidants; Catechin; Goblet Cells; Hyperplasia; Inhalation Exposure; Lung Injury; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Smoking; Tea; Tobacco Smoke Pollution | 2009 |
Epigallocatechin-3-gallate affects the growth of LNCaP cells via membrane fluidity and distribution of cellular zinc.
Topics: Catechin; Cell Line, Tumor; Cell Proliferation; Cell Size; Dose-Response Relationship, Drug; Humans; Male; Membrane Fluidity; Prostatic Neoplasms; Zinc | 2009 |
Epigallocatechin-3-gallate reduces DNA damage induced by benzo[a]pyrene diol epoxide and cigarette smoke condensate in human mucosa tissue cultures.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adolescent; Adult; Anticarcinogenic Agents; Antimutagenic Agents; Carcinogens; Catechin; Cells, Cultured; Comet Assay; DNA Damage; Female; Humans; Male; Middle Aged; Mouth Mucosa; Smoking; Young Adult | 2009 |
Effects of epigallocatechin gallate on the oral bioavailability and pharmacokinetics of tamoxifen and its main metabolite, 4-hydroxytamoxifen, in rats.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Hormonal; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Catechin; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Injections, Intravenous; Intestinal Mucosa; Liver; Male; Rats; Rats, Sprague-Dawley; Tamoxifen | 2009 |
Epigallocatechin-3-gallate exhibits anti-fibrotic effect by attenuating bleomycin-induced glycoconjugates, lysosomal hydrolases and ultrastructural changes in rat model pulmonary fibrosis.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Bleomycin; Bronchoalveolar Lavage Fluid; Catechin; Dose-Response Relationship, Drug; L-Lactate Dehydrogenase; Lung; Male; Pulmonary Fibrosis; Rats; Rats, Wistar | 2009 |
Green tea EGCG suppresses T cell proliferation through impairment of IL-2/IL-2 receptor signaling.
Topics: Animals; Catechin; Cell Cycle; Cell Division; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hydrogen Peroxide; Interleukin-2; Male; Mice; Mice, Inbred C57BL; Receptors, Interleukin-2; Signal Transduction; T-Lymphocytes; Tea; Vitamin E | 2009 |
(-)-Epigallocatechin-3-gallate (EGCG) sensitizes melanoma cells to interferon induced growth inhibition in a mouse model of human melanoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; fas Receptor; Humans; Interferon-alpha; Melanoma; Mice; Mice, Nude; NF-kappa B; Proliferating Cell Nuclear Antigen; Tea; Xenograft Model Antitumor Assays | 2009 |
Epigallocatechin-3-gallate improves nonalcoholic steatohepatitis model mice expressing nuclear sterol regulatory element binding protein-1c in adipose tissue.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adipose Tissue; Animals; Catechin; Deoxyguanosine; Fatty Liver; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Mice; Mice, Transgenic; Sterol Regulatory Element Binding Protein 1 | 2009 |
Biphasic regulation of polymorphonuclear leukocyte spreading by polyphenolic compounds with pyrogallol moieties.
Topics: Animals; Camellia sinensis; Catechin; Cell Adhesion; Cell Surface Extensions; Cells, Cultured; Chemotaxis; Fibrinogen; Neutrophils; Plant Extracts; Pyrogallol; Swine; Tannins | 2009 |
Regioselective synthesis of methylated epigallocatechin gallate via nitrobenzenesulfonyl (Ns) protecting group.
Topics: Animals; Catechin; Chemistry, Organic; Chemistry, Pharmaceutical; Drug Design; Humans; Inhibitory Concentration 50; Matrix Metalloproteinase 1; Matrix Metalloproteinase 7; Methylation; Mice; Models, Chemical; Recombinant Proteins; Stereoisomerism; Tea | 2009 |
Promoter demethylation of WIF-1 by epigallocatechin-3-gallate in lung cancer cells.
Topics: Adaptor Proteins, Signal Transducing; Anticarcinogenic Agents; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Luciferases; Lung Neoplasms; Promoter Regions, Genetic; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Urokinase-Type Plasminogen Activator | 2009 |
Green tea extract: a novel addition to the antihirsutism armamentarium?
Topics: Camellia sinensis; Catechin; Eflornithine; Flavonoids; Hirsutism; Humans; Phytotherapy; Plant Extracts | 2009 |
(-)-Epigallocatechin gallate enhances the expression of genes related to insulin sensitivity and adipocyte differentiation in 3T3-L1 adipocytes at an early stage of differentiation.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Catechin; Gene Expression Regulation, Developmental; Insulin; Lipid Metabolism; Mice; Regression Analysis; RNA, Messenger; Tea | 2009 |
Coupling reactions of catechins with natural aldehydes and allyl alcohols and radical scavenging activities of the triglyceride-soluble products.
Topics: Aldehydes; Biphenyl Compounds; Catechin; Free Radical Scavengers; Hot Temperature; Picrates; Propanols; Solubility; Triglycerides; Water | 2009 |
Antiviral effect of epigallocatechin gallate on enterovirus 71.
Topics: Animals; Antioxidants; Antiviral Agents; Catechin; Cell Line; Chlorocebus aethiops; Enterovirus A, Human; Fibroblasts; Glycogen Storage Disease Type I; Humans; Male; Oxidative Stress; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Vero Cells; Virus Replication | 2009 |
Epigallocatechin-3-gallate is an inhibitor of Na+, K(+)-ATPase by favoring the E1 conformation.
Topics: Animals; Catechin; Inhibitory Concentration 50; Kidney; Molecular Conformation; Sodium-Potassium-Exchanging ATPase; Swine | 2009 |
Solution structure of human cardiac troponin C in complex with the green tea polyphenol, (-)-epigallocatechin 3-gallate.
Topics: Catechin; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Myocardium; Protein Binding; Tea; Troponin C | 2009 |
(-)-Epigallocatechin-3-gallate reduces experimental colon injury in rats by regulating macrophage and mast cell.
Topics: Animals; Catechin; Chemotaxis; Colitis; Histamine; Macrophages; Male; Mast Cells; N-Formylmethionine Leucyl-Phenylalanine; Peroxidase; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid | 2010 |
Role of catechin quinones in the induction of EpRE-mediated gene expression.
Topics: Animals; Catechin; Cell Line, Tumor; Gene Expression Regulation; Genes, Reporter; Glutathione; Humans; Luciferases; Mice; NAD(P)H Dehydrogenase (Quinone); Response Elements; Transcription, Genetic; Transfection | 2008 |
New life for an "old" drink.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Catechin; Cell Cycle; Drug Therapy, Combination; Humans; Melanoma; Mice; Signal Transduction; Tea | 2009 |
Neuroprotective effect of epigallocatechin-3-gallate against beta-amyloid-induced oxidative and nitrosative cell death via augmentation of antioxidant defense capacity.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; Catechin; Cell Death; Cell Line; Glutamate-Cysteine Ligase; Glutathione; Hippocampus; Male; Microglia; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Nitrogen Species; Reactive Oxygen Species | 2009 |
(-)-Epigallocatechin gallate suppresses the growth of human hepatocellular carcinoma cells by inhibiting activation of the vascular endothelial growth factor-vascular endothelial growth factor receptor axis.
Topics: Animals; Anticarcinogenic Agents; bcl-X Protein; Blotting, Western; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Humans; Liver Neoplasms; Male; Mice; Mice, Nude; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2009 |
Fast GC-FID based metabolic fingerprinting of Japanese green tea leaf for its quality ranking prediction.
Topics: Catechin; Chromatography, Gas; Flame Ionization; Japan; Metabolomics; Multivariate Analysis; Plant Extracts; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Tea | 2009 |
Effect of laminin tyrosine-isoleucine-glycine-serine-arginine peptide on the growth of human prostate cancer (PC-3) cells in vitro.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Androgens; Caspase 9; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Humans; Laminin; Male; Membrane Potential, Mitochondrial; Models, Molecular; Molecular Conformation; Oligopeptides; Prostatic Neoplasms; Receptors, Laminin | 2009 |
(-)-Epigallocatechin gallate downregulates EGF receptor via phosphorylation at Ser1046/1047 by p38 MAPK in colon cancer cells.
Topics: Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Colonic Neoplasms; Down-Regulation; ErbB Receptors; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-cbl; Pyridines; Serine | 2009 |
UVB radiation induces human lens epithelial cell migration via NADPH oxidase-mediated generation of reactive oxygen species and up-regulation of matrix metalloproteinases.
Topics: Active Transport, Cell Nucleus; Blotting, Western; Catechin; Cell Line; Cell Movement; Cell Nucleus; Electrophoresis, Polyacrylamide Gel; Epithelial Cells; Flow Cytometry; Humans; Lens, Crystalline; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Microscopy, Fluorescence; NADPH Oxidases; NF-kappa B; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Ultraviolet Rays; Up-Regulation | 2009 |
(-)-Epigallocatechin gallate attenuates the induction of HSP27 stimulated by sphingosine 1-phosphate via suppression of phosphatidylinositol 3-kinase/Akt pathway in osteoblasts.
Topics: Animals; Animals, Newborn; Blotting, Western; Catechin; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; HSP27 Heat-Shock Proteins; Intracellular Signaling Peptides and Proteins; Lysophospholipids; Mice; Microscopy, Fluorescence; Models, Biological; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Sphingosine | 2009 |
Development of epigallocatechin gallate-eluting polymeric stent and its physicochemical, biomechanical and biological evaluations.
Topics: Animals; Aorta, Thoracic; Caproates; Catechin; Drug Delivery Systems; Drug-Eluting Stents; Lactones; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Polymers; Rats; Rats, Sprague-Dawley; Stents; Tensile Strength | 2009 |
Studies on the effects of oral administration of nutrient mixture, quercetin and red onions on the bioavailability of epigallocatechin gallate from green tea extract.
Topics: Administration, Oral; Adult; Animals; Biological Availability; Catechin; Dietary Supplements; Female; Humans; Male; Middle Aged; Onions; Plant Extracts; Quercetin; Rats; Rats, Wistar; Tea | 2010 |
Gingko biloba extract reduces VEGF and CXCL-8/IL-8 levels in keratinocytes with cumulative effect with epigallocatechin-3-gallate.
Topics: Anti-Inflammatory Agents; Catechin; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Ginkgo biloba; Humans; Interleukin-8; Keratinocytes; Male; Plant Extracts; Plant Leaves; Time Factors; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2010 |
(-)-Epigallocatechin-3-gallate induces apoptosis of human hepatoma cells by mitochondrial pathways related to reactive oxygen species.
Topics: Apoptosis; Catechin; Cell Line, Tumor; Cytochromes c; Humans; Liver Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Reactive Oxygen Species | 2009 |
Green tea catechin inhibits lipopolysaccharide-induced bone resorption in vivo.
Topics: Alveolar Bone Loss; Animals; Antioxidants; Bone Marrow Cells; Catechin; Cell Count; Cell Nucleus; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Escherichia coli; Interleukin-1beta; Interleukin-2 Receptor alpha Subunit; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophage Colony-Stimulating Factor; Macrophages; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Osteoclasts; RANK Ligand; Tea | 2010 |
JNK-dependent NFATc1 pathway positively regulates IL-13 gene expression induced by (-)-epigallocatechin-3-gallate in human basophilic KU812 cells.
Topics: Anthracenes; Basophils; Catechin; Cell Line; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression; Humans; Hydrogen Peroxide; Interleukin-13; JNK Mitogen-Activated Protein Kinases; NFATC Transcription Factors; Peroxides; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship; Up-Regulation | 2009 |
(-)-epigallocatechin-3-gallate (EGCG) maintains kappa-casein in its pre-fibrillar state without redirecting its aggregation pathway.
Topics: Amyloid; Animals; Caseins; Catechin; Circular Dichroism; Humans; Molecular Structure; Protein Binding; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary | 2009 |
Effect of lycopene and epigallocatechin-3-gallate against 3-nitropropionic acid induced cognitive dysfunction and glutathione depletion in rat: a novel nitric oxide mechanism.
Topics: Animals; Brain; Carotenoids; Catechin; Disease Models, Animal; Glutathione; Huntington Disease; Lycopene; Male; Maze Learning; Memory Disorders; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Rats | 2009 |
Catechins inhibit CXCL10 production from oncostatin M-stimulated human gingival fibroblasts.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Catechin; Cells, Cultured; Chemokine CXCL10; Cytokine Receptor gp130; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Gingiva; Humans; Oncostatin M; Oncostatin M Receptor beta Subunit; Osmolar Concentration; Periodontal Diseases; Phosphorylation; Signal Transduction | 2010 |
[Preparation, activity and targeting ability evaluation in vitro on folate mediated epigallocatechin-3-gallate albumin nanoparticles].
Topics: Antineoplastic Agents, Phytogenic; Catechin; Cell Death; Cell Line, Tumor; Drug Carriers; Drug Compounding; Drug Delivery Systems; Folic Acid; Humans; Male; Nanoparticles; Particle Size; Prostatic Neoplasms; Serum Albumin, Bovine | 2009 |
[Epigallocatechin-3-gallate induces G1 phase cell cycle arrest in KB cells].
Topics: Catechin; Cell Cycle; Cell Proliferation; Cyclin E; Flow Cytometry; G1 Phase Cell Cycle Checkpoints; Humans; KB Cells; Oncogene Proteins | 2009 |
Reversible regulation of cell cycle-related genes by epigallocatechin gallate for hibernation of neonatal human tarsal fibroblasts.
Topics: Catechin; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Cells, Cultured; Fibroblasts; Gene Expression Regulation; Humans; Infant; Male; Oligonucleotide Array Sequence Analysis; Tarsal Bones | 2009 |
Green tea polyphenol (-)-epigallocatechin-3-gallate enhances the inhibitory effect of huperzine A on acetylcholinesterase by increasing the affinity with serum albumin.
Topics: Acetylcholinesterase; Administration, Oral; Alkaloids; Anticarcinogenic Agents; Antioxidants; Beverages; Brain; Catechin; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Neuroprotective Agents; Serum Albumin; Sesquiterpenes | 2009 |
The green tea polyphenol EGCG potentiates the antiproliferative activity of c-Met and epidermal growth factor receptor inhibitors in non-small cell lung cancer cells.
Topics: Animals; Anticarcinogenic Agents; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Erlotinib Hydrochloride; Humans; Indoles; Lung Neoplasms; Male; Mice; Mice, SCID; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Quinazolines; Sulfonamides; Xenograft Model Antitumor Assays | 2009 |
Effects of epigallocatechin gallate on osteogenic capability of human mesenchymal stem cells after suspension in phosphate-buffered saline.
Topics: Adult; Antioxidants; Buffers; Catechin; Cell Differentiation; Cell Proliferation; Cell Survival; Cells, Cultured; Female; Humans; Male; Mesenchymal Stem Cells; Osteogenesis; Phosphates; Sodium Chloride | 2010 |
HIV type-1 entry inhibitors with a new mode of action.
Topics: Anti-HIV Agents; Binding Sites; Camellia sinensis; Catechin; Cell Line, Tumor; Cinnamomum zeylanicum; Dose-Response Relationship, Drug; Drug Discovery; Drug Synergism; Enfuvirtide; HIV Envelope Protein gp41; HIV Infections; HIV-1; Humans; Mass Spectrometry; Peptide Fragments; Plant Extracts; Reproducibility of Results; Sambucus; Time Factors; Virion; Virus Internalization | 2009 |
Epigallocatechin gallate ameliorates chronic fatigue syndrome in mice: behavioral and biochemical evidence.
Topics: Animals; Antioxidants; Brucella abortus; Catalase; Catechin; Disease Models, Animal; Fatigue Syndrome, Chronic; Glutathione; Hyperalgesia; Lipid Peroxidation; Lipopolysaccharides; Locomotion; Mice; Mice, Inbred Strains; Nitrites; Oxidative Stress; Superoxide Dismutase; Swimming; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2009 |
(-)-Epigallocatechin gallate prevents carbon tetrachloride-induced rat hepatic fibrosis by inhibiting the expression of the PDGFRbeta and IGF-1R.
Topics: Actins; Alanine Transaminase; Animals; Anticarcinogenic Agents; Aspartate Aminotransferases; Carbon Tetrachloride; Catechin; Gene Expression; Liver; Liver Cirrhosis; Male; Rats; Rats, Wistar; Receptor, IGF Type 1; Receptor, Platelet-Derived Growth Factor beta; RNA, Messenger | 2009 |
Inhibitory effects of epigallocatechin-3 gallate, a polyphenol in green tea, on tumor-associated endothelial cells and endothelial progenitor cells.
Topics: Animals; Anticarcinogenic Agents; Blotting, Western; Catechin; Cell Line, Tumor; Cell Movement; Down-Regulation; Endothelial Cells; Flavonoids; Flow Cytometry; Gene Expression; Humans; Matrix Metalloproteinase 9; Melanoma; Mice; Microvessels; Neovascularization, Pathologic; Phenols; Polyphenols; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stem Cells; Tea; Xenograft Model Antitumor Assays | 2009 |
(-)-Epigallocatechin-3-gallate (EGCG) increases the viability of serum-starved A549 cells through its effect on Akt.
Topics: Adaptor Proteins, Signal Transducing; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Catechin; Cell Line, Tumor; Cell Survival; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-raf; Time Factors | 2009 |
Green tea (-)-epigallocatechin-3-gallate inhibits beta-amyloid-induced cognitive dysfunction through modification of secretase activity via inhibition of ERK and NF-kappaB pathways in mice.
Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Apoptosis; Brain; Camellia sinensis; Catechin; Cognition; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Mice; Neurons; NF-kappa B; Presenilin-2 | 2009 |
EGCG inhibits protein synthesis, lipogenesis, and cell cycle progression through activation of AMPK in p53 positive and negative human hepatoma cells.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Anticarcinogenic Agents; Carcinoma, Hepatocellular; Catechin; Cell Cycle; Cell Line, Tumor; Fatty Acid Synthases; Humans; Lipogenesis; Liver Neoplasms; Protein Biosynthesis; Protein Kinases; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53 | 2009 |
Green tea epigallocatechin-3-gallate inhibits microsomal prostaglandin E(2) synthase-1.
Topics: Anticarcinogenic Agents; Camellia sinensis; Catechin; Dinoprostone; Enzyme Inhibitors; Humans; Intramolecular Oxidoreductases; Microsomes; Prostaglandin H2; Prostaglandin-E Synthases | 2009 |
Epigallocatechin-3-gallate enhances ischemia/reperfusion-induced apoptosis in human umbilical vein endothelial cells via AKT and MAPK pathways.
Topics: Apoptosis; bcl-2-Associated X Protein; Catechin; Cell Cycle Proteins; Cell Proliferation; Endothelial Cells; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Forkhead Box Protein O1; Forkhead Box Protein O3; Forkhead Transcription Factors; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Reperfusion Injury; Umbilical Veins | 2009 |
Degradation and metabolism of catechin, epigallocatechin-3-gallate (EGCG), and related compounds by the intestinal microbiota in the pig cecum model.
Topics: Animals; Bacteria; Catechin; Cecum; Flavonoids; Models, Biological; Proanthocyanidins; Stereoisomerism; Swine | 2009 |
50 Hz extremely low frequency electromagnetic fields enhance protein carbonyl groups content in cancer cells: effects on proteasomal systems.
Topics: Analysis of Variance; Caco-2 Cells; Carcinogens; Catechin; Cell Survival; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Radiation; Electromagnetic Fields; Humans; Neoplasms; Proteasome Endopeptidase Complex; Protein Carbonylation; Radiation-Protective Agents; Temperature; Tetradecanoylphorbol Acetate | 2009 |
Blockade of GRP78 sensitizes breast cancer cells to microtubules-interfering agents that induce the unfolded protein response.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Caspase 7; Catechin; Cell Line, Tumor; Endoplasmic Reticulum Chaperone BiP; Female; Heat-Shock Proteins; Humans; Microtubules; Paclitaxel; Phosphorylation; Poly(ADP-ribose) Polymerases; Unfolded Protein Response; Vinblastine | 2009 |
Epigallocatechin-3-gallate (EGCG) affects the antioxidant and immune defense of the rainbow trout, Oncorhynchus mykiss.
Topics: Analysis of Variance; Animals; Antioxidants; Catechin; Complement Pathway, Alternative; Dietary Supplements; Flow Cytometry; Lipid Peroxides; Liver; Muramidase; Oncorhynchus mykiss; Reactive Oxygen Species; Superoxide Dismutase; Vitamin E | 2010 |
A fluorometric assay of SIRT1 deacetylation activity through quantification of nicotinamide adenine dinucleotide.
Topics: Catechin; Coumarins; Fluorescent Dyes; NAD; Peptides; Resveratrol; Sirtuin 1; Spectrometry, Fluorescence; Stilbenes | 2009 |
Artefacts in cell culture: pyruvate as a scavenger of hydrogen peroxide generated by ascorbate or epigallocatechin gallate in cell culture media.
Topics: Artifacts; Ascorbic Acid; Catechin; Culture Media; Free Radical Scavengers; Hydrogen Peroxide; Pyruvic Acid | 2009 |
[Effects of (-)-epigallocatechin-3-gallate on interleukin-1beta expression in mouse wound healing].
Topics: Animals; Catechin; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation; Interleukin-1beta; Male; Mice; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Wound Healing | 2009 |
Effects of epigallocatechin gallate on rotenone-injured murine brain cultures.
Topics: Animals; Brain Injuries; Catechin; Cell Count; Cells, Cultured; Corpus Striatum; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Neurites; Neurons; Neuroprotective Agents; Nitric Oxide; Rotenone; Superoxides; Tissue Culture Techniques; Tyrosine 3-Monooxygenase | 2010 |
Oral pre-treatment with epigallocatechin gallate in 6-OHDA lesioned rats produces subtle symptomatic relief but not neuroprotection.
Topics: Administration, Oral; Adrenergic Agents; Animals; Antioxidants; Catechin; Cell Count; Dopamine; Dyskinesia, Drug-Induced; Female; Immunohistochemistry; Motor Activity; Neurons; Neuropsychological Tests; Oxidopamine; Posture; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra | 2009 |
Modulation of NRF2 and UGT1A expression by epigallocatechin-3-gallate in colon cancer cells and BALB/c mice.
Topics: Animals; Anticarcinogenic Agents; Blotting, Western; Caco-2 Cells; Catechin; Colonic Neoplasms; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Glucuronosyltransferase; Humans; Male; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Modulation of arsenic trioxide-induced apoptosis by genistein and functionally related agents in U937 human leukaemia cells. Regulation by ROS and mitogen-activated protein kinases.
Topics: Adamantane; Antineoplastic Agents; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Catechin; Cell Cycle; Drug Synergism; Enzyme Activation; Estradiol; Etoposide; Genistein; HL-60 Cells; Humans; Hydroquinones; Immunoblotting; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Oxides; Protein Kinase Inhibitors; Reactive Oxygen Species; RNA, Small Interfering; U937 Cells | 2009 |
Some phenolic compounds increase the nitric oxide level in endothelial cells in vitro.
Topics: Catechin; Cell Line; Endothelial Cells; Gene Expression; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Phenols; Quercetin; Resveratrol; Stilbenes | 2009 |
Green tea catechin controls apoptosis in colon cancer cells by attenuation of H2O2-stimulated COX-2 expression via the AMPK signaling pathway at low-dose H2O2.
Topics: Acetylcysteine; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Apoptosis; Blotting, Western; Catechin; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Free Radical Scavengers; HT29 Cells; Humans; Hydrogen Peroxide; Oxidants; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Ribonucleotides; Signal Transduction; Tea; Tumor Suppressor Protein p53 | 2009 |
[Effects of epigallocatechin-3-gallate on the proliferation of colonic cancer cell line SW620 and PAK1 gene expression].
Topics: Blotting, Western; Catechin; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Humans; p21-Activated Kinases | 2009 |
Differentiation-associated alteration in sensitivity to apoptosis induced by (-)-epigallocatechin-3-O-gallate in HL-60 cells.
Topics: Antioxidants; Apoptosis; Catechin; Cell Differentiation; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Receptors, Laminin; Tea | 2009 |
Attenuation of the inflammatory changes and lipid anomalies by epigallocatechin-3-gallate in hypercholesterolemic diet fed aged rats.
Topics: Aging; Animals; Antioxidants; Atherosclerosis; Biomarkers; Catechin; Diet, Atherogenic; Hypercholesterolemia; Inflammation; Lipids; Male; Rats; Rats, Wistar | 2009 |
Effects of co-administration of tea epigallocatechin-3-gallate (EGCG) and caffeine on absorption and metabolism of EGCG in humans.
Topics: Adult; Caffeine; Catechin; Chromatography, High Pressure Liquid; Humans; Luminescence; Spectrophotometry, Ultraviolet; Tea | 2009 |
Nonfrozen preservation of articular cartilage by epigallocatechin-3-gallate reversibly regulating cell cycle and NF-kappaB expression.
Topics: Aged; Aged, 80 and over; Animals; Biomechanical Phenomena; Cartilage, Articular; Catechin; Cell Cycle; Cell Survival; Chondrocytes; Collagen; Cyclins; Extracellular Matrix; Female; Freezing; Glycosaminoglycans; Humans; Male; Middle Aged; NF-kappa B; Rabbits; Tissue Preservation | 2010 |
Suppression of Met activation in human colon cancer cells treated with (-)-epigallocatechin-3-gallate: minor role of hydrogen peroxide.
Topics: Antineoplastic Agents; Antioxidants; Catechin; Cell Line, Tumor; Colonic Neoplasms; Humans; Hydrogen Peroxide; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Receptors, Growth Factor | 2009 |
Inhibition of cyclooxygenase-2 expression and prostaglandin E2 production in chondrocytes by avocado soybean unsaponifiables and epigallocatechin gallate.
Topics: Aggrecans; Animals; Antioxidants; Cartilage, Articular; Catechin; Chondrocytes; Collagen Type II; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Gene Expression; Glycine max; Horses; Interleukin-1beta; NF-kappa B; Persea; Phenotype; Plant Extracts; Polymerase Chain Reaction; RNA; Tumor Necrosis Factor-alpha | 2010 |
Prooxidative effects of green tea polyphenol (-)-epigallocatechin-3-gallate on the HIT-T15 pancreatic beta cell line.
Topics: Apoptosis; Catechin; Cell Line; Cell Survival; Comet Assay; Dose-Response Relationship, Drug; Flavonoids; Hydrogen Peroxide; Insulin-Secreting Cells; Oxidants; Oxidative Stress; Phenols; Polyphenols; Reactive Oxygen Species; Tea | 2010 |
Select phytochemicals suppress human T-lymphocytes and mouse splenocytes suggesting their use in autoimmunity and transplantation.
Topics: Animals; Anthocyanins; Autoimmunity; Catechin; CD28 Antigens; CD3 Complex; Cell Line; Cell Proliferation; Curcumin; Female; Humans; Immunosuppressive Agents; Interleukin-2; Isothiocyanates; Magnoliopsida; Mice; Mice, Inbred BALB C; Organ Transplantation; Plant Extracts; Quercetin; Spleen; Sulfoxides; T-Lymphocytes; Thiocyanates | 2009 |
Protective effects of epigallocatechin gallate following 3-nitropropionic acid-induced brain damage: possible nitric oxide mechanisms.
Topics: Animals; Antioxidants; Behavior, Animal; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mitochondria; Motor Activity; Neurodegenerative Diseases; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; Nitric Oxide; Nitro Compounds; Oxidative Stress; Propionates; Rats; Rats, Wistar | 2009 |
Bioavailability of catechins from ready-to-drink tea.
Topics: Adolescent; Adult; Biological Availability; Catechin; Chromatography, High Pressure Liquid; Female; Flavonoids; Gallic Acid; Humans; Male; Middle Aged; Tandem Mass Spectrometry; Tea | 2010 |
Phytochemical characterization of an adaptogenic preparation from Rhodiola heterodonta.
Topics: Animals; Catechin; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Liquid; Ethanol; Glucosides; Hypoxia; Mass Spectrometry; Mice; Phenols; Phenylethyl Alcohol; Plant Preparations; Proanthocyanidins; Rhodiola | 2009 |
Green tea (-)-epigalocatechin-3-gallate inhibits KIT activity and causes caspase-dependent cell death in gastrointestinal stromal tumor including imatinib-resistant cells.
Topics: Animals; Apoptosis; Benzamides; Blotting, Western; Caspase 3; Caspase 8; Caspase 9; Caspases; Catechin; Cell Line; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Tea; Time Factors | 2009 |
[Studies on the chemical comstituents of Pithecellobium clypearia].
Topics: Antiviral Agents; Catechin; Chromatography, High Pressure Liquid; Fabaceae; Flavonoids; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Leaves; Plant Stems; Plants, Medicinal; Stereoisomerism | 2009 |
[Purification of EGCG monomer from the extracts of tea by high speed countercurrent chromatography].
Topics: Acetates; Catechin; Chromatography, High Pressure Liquid; Countercurrent Distribution; Ether; Molecular Structure; Plant Extracts; Solvents; Tea | 2009 |
Beneficial storage effects of epigallocatechin-3-o-gallate on the articular cartilage of rabbit osteochondral allografts.
Topics: Animals; Antioxidants; Cartilage, Articular; Catechin; Glycosaminoglycans; Hyaline Cartilage; Rabbits; Time Factors; Tissue Preservation; Transplantation, Homologous | 2009 |
Long-term preservation of rat skin tissue by epigallocatechin-3-o-gallate.
Topics: Animals; Antioxidants; Catechin; Cryopreservation; Glucose; Male; Mice; Mice, Nude; Rats; Skin; Skin Transplantation; Time Factors; Tissue Preservation | 2009 |
Preservation of platelets by adding epigallocatechin-3-o-gallate to platelet concentrates.
Topics: Antioxidants; Apoptosis; Blood Platelets; Blood Preservation; Caspase 3; Catechin; Chemokine CCL5; Gelsolin; Humans; L-Lactate Dehydrogenase; P-Selectin; Thromboplastin | 2009 |
Effects of (-)-epigallocatechin-3-gallate on cyclooxygenase 2, PGE(2), and IL-8 expression induced by IL-1beta in human synovial fibroblasts.
Topics: Aged; Aged, 80 and over; Catechin; Cyclooxygenase 2; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Genes; Humans; Interleukin-1beta; Interleukin-8; Middle Aged; Osteoarthritis; Prostaglandins E; Reverse Transcriptase Polymerase Chain Reaction; Synovial Membrane; Up-Regulation | 2010 |
EGCG induces apoptosis in human laryngeal epidermoid carcinoma Hep2 cells via mitochondria with the release of apoptosis-inducing factor and endonuclease G.
Topics: Anticarcinogenic Agents; Apoptosis Inducing Factor; Blotting, Western; Carcinoma, Squamous Cell; Catechin; Cell Cycle; Cell Line, Tumor; Endodeoxyribonucleases; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Laryngeal Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Tumor Suppressor Protein p53 | 2010 |
Regulatory effect of epigallocatechin gallate on the expression of C-reactive protein and other inflammatory markers in an experimental model of atherosclerosis.
Topics: Animals; Aorta, Thoracic; Atherosclerosis; Biomarkers; Blood Sedimentation; C-Reactive Protein; Catechin; Diet, Atherogenic; Disease Models, Animal; Inflammation; Injections, Intraperitoneal; Lymphocyte Count; Male; Platelet Count; Rats; Rats, Wistar | 2010 |
Apoptosis induction effects of EGCG in laryngeal squamous cell carcinoma cells through telomerase repression.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Catechin; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; G1 Phase; Humans; Laryngeal Neoplasms; Telomerase | 2009 |
Cell growth inhibition and gene expression regulation by (-)-epigallocatechin-3-gallate in human cervical cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Aromatase; Catechin; Cell Cycle; Cell Proliferation; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Human papillomavirus 16; Humans; Uterine Cervical Neoplasms | 2009 |
Skin penetration of epigallocatechin-3-gallate and quercetin from green tea and Ginkgo biloba extracts vehiculated in cosmetic formulations.
Topics: Administration, Cutaneous; Antioxidants; Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Cosmetics; Diffusion Chambers, Culture; Ginkgo biloba; Humans; In Vitro Techniques; Permeability; Plant Extracts; Quercetin; Skin Absorption; Time Factors | 2009 |
Analysis of flavonoid-based pharmacophores that inhibit aggrecanases (ADAMTS-4 and ADAMTS-5) and matrix metalloproteinases through the use of topologically constrained peptide substrates.
Topics: ADAM Proteins; ADAMTS4 Protein; ADAMTS5 Protein; Amino Acid Sequence; Antioxidants; Catechin; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Molecular Sequence Data; Molecular Structure; Peptides; Procollagen N-Endopeptidase; Stilbenes | 2009 |
Oxidative modification of citrate synthase by peroxyl radicals and protection with novel antioxidants.
Topics: Aconitate Hydratase; Amidines; Antioxidants; Ascorbic Acid; Catechin; Citrate (si)-Synthase; Enzyme Activation; Glutathione; Inhibitory Concentration 50; Mitochondria; Naphthols; Oxaloacetic Acid; Oxidants; Oxidation-Reduction; Oxidative Stress; Peroxides; Propyl Gallate | 2009 |
Epigallocatechin gallate (EGCG) and rutin suppress the glucotoxicity through activating IRS2 and AMPK signaling in rat pancreatic beta cells.
Topics: AMP-Activated Protein Kinases; Animals; Catechin; Cell Line, Tumor; Diabetes Mellitus, Type 2; Down-Regulation; Glucose; Humans; Insulin Receptor Substrate Proteins; Insulin-Secreting Cells; Rats; Rutin; Signal Transduction | 2009 |
A metabolite profiling approach to identify biomarkers of flavonoid intake in humans.
Topics: Adult; Biomarkers; Body Mass Index; Catechin; Flavonoids; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Male; Middle Aged; Nitrates; Nitrites; Phenols; Quercetin; Time Factors | 2009 |
Effects of epigallocatechin gallate on tissue protection and functional recovery after contusive spinal cord injury in rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Catechin; Dyskinesias; Female; Immunohistochemistry; In Situ Nick-End Labeling; Lipid Peroxidation; Neuroprotective Agents; Neuropsychological Tests; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord; Spinal Cord Injuries; Time Factors; Treatment Outcome | 2010 |
Antiproliferative and proapoptotic effects of epigallocatechin gallate on human leiomyoma cells.
Topics: Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Camellia sinensis; Catechin; Cell Proliferation; Cyclin-Dependent Kinase 4; Dose-Response Relationship, Drug; Female; Humans; Leiomyoma; Plant Extracts; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tea; Time Factors; Tumor Cells, Cultured; Uterine Neoplasms | 2010 |
Epigallocatechin-3-O-gallate (EGCG) protects the insulin sensitivity in rat L6 muscle cells exposed to dexamethasone condition.
Topics: AMP-Activated Protein Kinases; Animals; Biological Transport; Camellia sinensis; Catechin; Cell Line; Cell Membrane; Dexamethasone; Flavonoids; Glucocorticoids; Glucose; Glucose Metabolism Disorders; Glucose Transporter Type 4; Insulin Receptor Substrate Proteins; Insulin Resistance; Muscle Cells; Phenols; Phosphorylation; Phytotherapy; Plant Extracts; Polyphenols; Proto-Oncogene Proteins c-akt; Rats; Serine; Tea | 2010 |
Epigallocatechin-3-gallate inhibits osteoclastogenesis by down-regulating c-Fos expression and suppressing the nuclear factor-kappaB signal.
Topics: Animals; Bone Marrow Cells; Bone Resorption; Catechin; Cells, Cultured; Coculture Techniques; Down-Regulation; Gene Expression Regulation; Mice; NF-kappa B; NFATC Transcription Factors; Osteoclasts; Osteoprotegerin; Proto-Oncogene Proteins c-fos; RANK Ligand; Signal Transduction | 2010 |
The effect of epigallocatechin gallate on lipopolysaccharide-induced acute lung injury in a murine model.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Catechin; Cell Line; Chemokine CXCL2; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Lung; Macrophages; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neutrophil Infiltration; Organ Size; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Severity of Illness Index; Tumor Necrosis Factor-alpha | 2010 |
Targeting CWR22Rv1 prostate cancer cell proliferation and gene expression by combinations of the phytochemicals EGCG, genistein and quercetin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Catechin; Cell Growth Processes; Cell Line, Tumor; Culture Media, Serum-Free; Drug Synergism; Gene Expression; Genistein; Humans; Male; Neoplastic Stem Cells; Phytotherapy; Prostatic Neoplasms; Quercetin; Tumor Suppressor Protein p53 | 2009 |
Binding of epigallocatechin-3-gallate to transthyretin modulates its amyloidogenicity.
Topics: Amino Acid Substitution; Amyloid; Animals; Binding Sites; Binding, Competitive; Catechin; Cell Line; Humans; Microscopy, Electron, Transmission; Mutation; Prealbumin; Protein Binding; Protein Conformation; Thyroxine; Transfection | 2009 |
Chemical composition of the Lippia origanoides essential oils and their antigenotoxicity against bleomycin-induced DNA damage.
Topics: Antimutagenic Agents; Bleomycin; Catechin; Cell Culture Techniques; Cymenes; DNA Damage; Escherichia coli; Flowers; Gas Chromatography-Mass Spectrometry; Lippia; Monoterpenes; Oils, Volatile; Plant Extracts; Plant Leaves; Thymol | 2010 |
Separation of major catechins from green tea by ultrahigh pressure extraction.
Topics: Caffeine; Camellia sinensis; Catechin; Chemical Fractionation; Chromatography, High Pressure Liquid; Plant Leaves; Pressure; Solvents; Time Factors | 2010 |
Hepatotoxicity of high oral dose (-)-epigallocatechin-3-gallate in mice.
Topics: Aldehydes; Animals; Antioxidants; Biomarkers; Catechin; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cysteine; Cytokines; Dose-Response Relationship, Drug; Immunohistochemistry; Lipid Peroxidation; Liver Function Tests; Male; Metallothionein; Mice; Oxidants; Oxidative Stress; Spectrometry, Mass, Electrospray Ionization; Survival Analysis | 2010 |
Tea, coffee, and cocoa as ultraviolet radiation protectants for the beet armyworm nucleopolyhedrovirus.
Topics: Animals; Cacao; Caffeine; Catechin; Coffee; Nucleopolyhedroviruses; Plant Extracts; Radiation-Protective Agents; Spodoptera; Tea; Ultraviolet Rays | 2009 |
Green tea polyphenol epigallocatechin gallate reduces endothelin-1 expression and secretion in vascular endothelial cells: roles for AMP-activated protein kinase, Akt, and FOXO1.
Topics: AMP-Activated Protein Kinases; Animals; Binding Sites; Catechin; Cattle; Cells, Cultured; Down-Regulation; Endothelial Cells; Endothelin-1; Flavonoids; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression; Humans; Mice; NIH 3T3 Cells; Oncogene Protein v-akt; Phenols; Polyphenols; Promoter Regions, Genetic; Tea | 2010 |
Flavonoids activated caspases for apoptosis in human glioblastoma T98G and U87MG cells but not in human normal astrocytes.
Topics: Apoptosis; Astrocytes; BH3 Interacting Domain Death Agonist Protein; Brain Neoplasms; Caspase 8; Caspases; Catechin; Cell Line; Cell Line, Tumor; Enzyme Activation; Flavonoids; Glioblastoma; Humans; Membrane Potential, Mitochondrial; Mitogen-Activated Protein Kinase 8; Reactive Oxygen Species | 2010 |
Tea catechins' affinity for human cannabinoid receptors.
Topics: Camellia sinensis; Cannabinoids; Catechin; Cell Line; Humans; Ligands; Plant Extracts; Plant Leaves; Receptors, Cannabinoid; Recombinant Proteins; Signal Transduction; Tea | 2010 |
Catechins inhibit CCL20 production in IL-17A-stimulated human gingival fibroblasts.
Topics: Antioxidants; Catechin; Cells, Cultured; Chemokine CCL20; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Gingiva; Humans; Interleukin-17; p38 Mitogen-Activated Protein Kinases; Phosphorylation | 2009 |
Epigallocatechin-3-O-gallate decreases tumor necrosis factor-alpha-induced fractalkine expression in endothelial cells by suppressing NF-kappaB.
Topics: Anti-Inflammatory Agents; Catechin; Cell Line; Chemokine CX3CL1; Endothelial Cells; Humans; I-kappa B Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; RNA, Small Interfering; Tumor Necrosis Factor-alpha | 2009 |
Epigallocatechin gallate reduces human monocyte mobility and adhesion in vitro.
Topics: Anti-Inflammatory Agents; Catechin; Cell Adhesion; Cell Line; Cell Movement; Chemokine CCL2; Gene Expression Regulation; Humans; Integrin beta1; Monocytes; Receptors, CCR2 | 2009 |
A synergistic small-molecule combination directly eradicates diverse prion strain structures.
Topics: Aniline Compounds; Catechin; Drug Synergism; Heat-Shock Proteins; Models, Chemical; Models, Molecular; Peptide Termination Factors; Phthalimides; Prions; Protein Conformation; Protein Folding; Saccharomyces cerevisiae Proteins; Small Molecule Libraries | 2009 |
Depigmenting effect of catechins.
Topics: Animals; Catechin; Cell Line, Tumor; Cell Proliferation; Gallic Acid; Gene Expression; Melanins; Mice; Molecular Structure; Monophenol Monooxygenase | 2009 |
Indoleamine 2,3-dioxygenase, an immunomodulatory protein, is suppressed by (-)-epigallocatechin-3-gallate via blocking of gamma-interferon-induced JAK-PKC-delta-STAT1 signaling in human oral cancer cells.
Topics: Catechin; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Enzymologic; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Janus Kinases; Mouth Neoplasms; Protein Kinase C-delta; Signal Transduction; STAT1 Transcription Factor | 2010 |
Green tea, black tea, and epigallocatechin modify body composition, improve glucose tolerance, and differentially alter metabolic gene expression in rats fed a high-fat diet.
Topics: Adipocytes; Adipose Tissue; Animals; Antioxidants; Biomarkers; Body Composition; Camellia sinensis; Catechin; Cell Differentiation; Diet, Atherogenic; Dietary Fats; Fatty Acids; Gene Expression; Gene Expression Regulation; Glucose Intolerance; Liver; Male; Metabolic Syndrome; Muscle, Skeletal; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tea; Thermogenesis | 2009 |
Green tea catechins: inhibitors of glycerol-3-phosphate dehydrogenase.
Topics: Catechin; Drug Evaluation, Preclinical; Glycerol-3-Phosphate Dehydrogenase (NAD+); Triglycerides | 2010 |
(-)-Epigallocatechin-3-gallate decreases thrombin/paclitaxel-induced endothelial tissue factor expression via the inhibition of c-Jun terminal NH2 kinase phosphorylation.
Topics: Anthracenes; Catechin; Cells, Cultured; Drug-Eluting Stents; Endothelium, Vascular; Humans; JNK Mitogen-Activated Protein Kinases; Paclitaxel; Phosphorylation; Thrombin; Thromboplastin; Transcription Factor RelA | 2010 |
Green tea polyphenol (-)-epigallocatechin gallate suppressed the differentiation of murine osteoblastic MC3T3-E1 cells.
Topics: Animals; Bone Marrow Cells; Catechin; Cell Differentiation; Cell Line; Coculture Techniques; Mice; Osteoblasts; Tea | 2009 |
Antitumor activity of novel fluoro-substituted (-)-epigallocatechin-3-gallate analogs.
Topics: Animals; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Female; Fluorine; Humans; Hydrocarbons, Fluorinated; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Proteasome Inhibitors; Xenograft Model Antitumor Assays | 2010 |
Green tea polyphenol (-)-epigallocatechin gallate reduces matrix metalloproteinase-9 activity following transient focal cerebral ischemia.
Topics: Animals; Catechin; Flavonoids; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Phenols; Polyphenols; Tea; Tetrazolium Salts; Up-Regulation | 2010 |
Intramuscular adaptations to eccentric exercise and antioxidant supplementation.
Topics: Acetylcysteine; Adaptation, Physiological; Adult; Antioxidants; Catechin; Dietary Supplements; Double-Blind Method; Exercise; Exercise Test; Humans; Male; Muscle Contraction; Muscle, Skeletal; Young Adult | 2010 |
(-)-Epigallocatechin-3-gallate induces Du145 prostate cancer cell death via downregulation of inhibitor of DNA binding 2, a dominant negative helix-loop-helix protein.
Topics: Apoptosis; Catechin; Cell Line, Tumor; Down-Regulation; Humans; Inhibitor of Differentiation Protein 2; Male; Prostatic Neoplasms | 2010 |
Potentiation of (-)-epigallocatechin-3-gallate-induced apoptosis by bortezomib in multiple myeloma cells.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Boronic Acids; Bortezomib; Catechin; Cell Line, Tumor; Humans; Multiple Myeloma; Polymerase Chain Reaction; Pyrazines; RNA, Messenger; Tea; Transcription Factor RelA | 2009 |
(-)-Epigallocatechin-3-gallate increases cell proliferation and neuroblasts in the subgranular zone of the dentate gyrus in adult mice.
Topics: Administration, Oral; Animals; Catechin; Cell Proliferation; Dentate Gyrus; Doublecortin Protein; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Neurons | 2010 |
Binding affinity of tea catechins for HSA: characterization by high-performance affinity chromatography with immobilized albumin column.
Topics: Catechin; Chromatography, Affinity; Humans; Protein Binding; Serum Albumin; Structure-Activity Relationship | 2010 |
Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons.
Topics: Apigenin; Calcium Signaling; Catechin; Cells, Cultured; Curcumin; Enzyme Activation; Flavanones; Flavonoids; Humans; Hydrolyzable Tannins; L-Lactate Dehydrogenase; NAD; Neurons; Neuroprotective Agents; Nitric Oxide Synthase Type I; Phenols; Poly(ADP-ribose) Polymerases; Polyphenols; Quinolinic Acid; Tyrosine | 2010 |
The Bmi-1 polycomb protein antagonizes the (-)-epigallocatechin-3-gallate-dependent suppression of skin cancer cell survival.
Topics: Anticarcinogenic Agents; Apoptosis; Carcinoma, Squamous Cell; Catechin; Cell Count; Cell Cycle Proteins; Cell Line, Transformed; Cell Line, Tumor; Culture Media, Serum-Free; DNA Replication; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Knockdown Techniques; Genetic Vectors; Humans; Keratinocytes; Neoplasm Proteins; Nuclear Proteins; Polycomb Repressive Complex 1; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Repressor Proteins; Skin Neoplasms; Transcription Factors | 2010 |
[Epigallocatechin gallate induces apoptosis in human hepatocellular carcinoma HepG2 cells via TGF/Smad signaling pathway].
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Cycle; Hep G2 Cells; Humans; RNA, Messenger; Signal Transduction; Smad Proteins; Smad7 Protein; Transforming Growth Factor beta1 | 2009 |
Inhibitory effects of (-)-epigallocatechin-3-gallate from green tea on the growth of Babesia parasites.
Topics: Animals; Babesia; Babesiosis; Camellia sinensis; Catechin; Erythrocytes; Female; Inhibitory Concentration 50; Mice; Mice, Inbred BALB C; Parasitemia | 2010 |
Neuroprotective effects of (-)-epigallocatechin-3-gallate against quinolinic acid-induced excitotoxicity via PI3K pathway and NO inhibition.
Topics: Animals; Apoptosis; Calcium; Catechin; Cell Line; Cell Survival; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Mice; Neurons; Neuroprotective Agents; Neurotoxins; Nitric Oxide; Phosphatidylinositol 3-Kinases; Quinolinic Acid; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Time Factors | 2010 |
Residue Glu83 plays a major role in negatively regulating alpha-synuclein amyloid formation.
Topics: alpha-Synuclein; Amyloid; Catechin; Dopamine; Flavanones; Glutamic Acid; Humans; Mutation; Neurodegenerative Diseases; Neuroprotective Agents | 2010 |
A pro-drug of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) prevents differentiated SH-SY5Y cells from toxicity induced by 6-hydroxydopamine.
Topics: Caspase 3; Catechin; Cell Line, Tumor; Central Nervous System Agents; Dose-Response Relationship, Drug; Humans; L-Lactate Dehydrogenase; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Time Factors; Tretinoin | 2010 |
EGCG enhances TRAIL-mediated apoptosis in human melanoma A375 cell line.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 8; Catechin; Cell Line, Tumor; Drug Synergism; Humans; Melanoma; Receptors, TNF-Related Apoptosis-Inducing Ligand; Skin Neoplasms; TNF-Related Apoptosis-Inducing Ligand | 2009 |
(-)-Epigallocatechin-3-gallate inhibits invasion and migration of salivary gland adenocarcinoma cells.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Catechin; Cell Adhesion; Cell Movement; Cell Survival; Down-Regulation; Drug Evaluation, Preclinical; Gene Expression Regulation, Neoplastic; Humans; Integrin beta1; Matrix Metalloproteinases; Neoplasm Invasiveness; Salivary Gland Neoplasms; Tumor Cells, Cultured | 2010 |
Metabolism of (-)-epigallocatechin gallate by rat intestinal flora.
Topics: Animals; Bacteria; Catechin; Feces; Intestinal Mucosa; Intestines; Male; Rats; Rats, Wistar | 2010 |
Proteasome inhibition in human breast cancer cells with high catechol-O-methyltransferase activity by green tea polyphenol EGCG analogs.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Catechin; Catechol O-Methyltransferase; Cell Survival; Female; Humans; Prodrugs; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Tea | 2010 |
Green tea catechin EGCG inhibits ileal apical sodium bile acid transporter ASBT.
Topics: Biological Transport; Biotinylation; Caco-2 Cells; Catechin; Cell Line; Cell Membrane; Enzyme Inhibitors; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Humans; Ileum; Kinetics; Membrane Lipids; Membrane Microdomains; Membrane Proteins; Octoxynol; Organic Anion Transporters, Sodium-Dependent; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Signal Transduction; Symporters; Taurocholic Acid; Tea; Transfection | 2010 |
Evaluation of resveratrol oxidation in vitro and the crucial role of bicarbonate ions.
Topics: Bicarbonates; Butanols; Catalase; Catechin; Culture Media; HEPES; Hydrogen-Ion Concentration; Nitrogen; Oxidation-Reduction; Phosphates; Pyruvic Acid; Resveratrol; Sodium Bicarbonate; Stilbenes; Tromethamine; Water | 2010 |
Lipid/particle assemblies based on maltodextrin-gum arabic core as bio-carriers.
Topics: Amines; Catechin; Drug Carriers; Egg Yolk; Gum Arabic; Membranes, Artificial; Nanoparticles; Particle Size; Phosphatidylcholines; Polysaccharides; Surface Properties | 2010 |
Ambivalent role of gallated catechins in glucose tolerance in humans: a novel insight into non-absorbable gallated catechin-derived inhibitors of glucose absorption.
Topics: 3T3-L1 Cells; Adult; Animals; Catechin; Cell Line; Drug Administration Routes; Glucose; Glucose Intolerance; Hep G2 Cells; Humans; Intestinal Absorption; Male; Mice; Mice, Knockout; Plant Extracts; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Tea; Young Adult | 2009 |
Food-derived bioactives as potential regulators of the IL-12/IL-23 pathway implicated in inflammatory bowel diseases.
Topics: Caffeic Acids; Catechin; Cell Line, Tumor; Docosahexaenoic Acids; Food; Humans; Interleukin-12; Interleukin-23; Signal Transduction; Tumor Necrosis Factor-alpha | 2010 |
Synergistic and additive effects of epigallocatechin gallate and digitonin on Plasmodium sporozoite survival and motility.
Topics: Animals; Catechin; Digitonin; Drug Synergism; Liver; Plasmodium berghei | 2010 |
Green tea extract inhibits proliferation of uterine leiomyoma cells in vitro and in nude mice.
Topics: Animals; Antioxidants; Apoptosis; Catechin; Cell Proliferation; Cyclin-Dependent Kinase 4; Female; Leiomyoma; Mice; Mice, Nude; Proliferating Cell Nuclear Antigen; Tumor Cells, Cultured; Uterine Neoplasms | 2010 |
(-)-Epigallocatechin gallate sensitizes breast cancer cells to paclitaxel in a murine model of breast carcinoma.
Topics: Animals; Apoptosis; Catechin; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Female; Heat-Shock Proteins; Humans; JNK Mitogen-Activated Protein Kinases; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Paclitaxel | 2010 |
Nanolipidic particles improve the bioavailability and alpha-secretase inducing ability of epigallocatechin-3-gallate (EGCG) for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Biological Availability; Catechin; Cell Line, Tumor; Enzyme Induction; Humans; Lipids; Male; Mice; Nanoparticles; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2010 |
Protective effect of epigallocatechin gallate in murine water-immersion stress model of chronic fatigue syndrome.
Topics: Administration, Oral; Animals; Antioxidants; Brain; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Fatigue Syndrome, Chronic; Mice; Oxidative Stress; Spleen; Swimming; Thymus Gland; Tumor Necrosis Factor-alpha | 2010 |
Epigallocatechin-3-gallate induces cell death in acute myeloid leukaemia cells and supports all-trans retinoic acid-induced neutrophil differentiation via death-associated protein kinase 2.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Catechin; Cell Death; Cell Differentiation; Death-Associated Protein Kinases; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gene Knockdown Techniques; Humans; Leukemia, Myeloid, Acute; Neutrophils; Reverse Transcriptase Polymerase Chain Reaction; Tretinoin; Tumor Cells, Cultured; Up-Regulation | 2010 |
Fish oil enhances anti-amyloidogenic properties of green tea EGCG in Tg2576 mice.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Protein Precursor; Animals; Biological Availability; Brain; Catechin; Cell Line, Tumor; Drug Synergism; Female; Fish Oils; Mice; Mice, Transgenic; Tea | 2010 |
Epigallocatechin-3-gallate inhibits interleukin-6- and angiotensin II-induced production of C-reactive protein in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Antioxidants; Aorta, Thoracic; C-Reactive Protein; Catechin; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Interleukin-6; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
Effect of dietary Polyphenon E and EGCG on lung tumorigenesis in A/J Mice.
Topics: Animals; Anticarcinogenic Agents; Catechin; Chemoprevention; Female; Lung; Lung Neoplasms; Mice | 2010 |
Effects of epigallocatechin-3-gallate on rat retinal ganglion cells after optic nerve axotomy.
Topics: Animals; Axotomy; bcl-2-Associated X Protein; Blotting, Western; Catechin; Cell Count; Cell Survival; Enzyme Inhibitors; Female; Injections, Intraperitoneal; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 6; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Optic Nerve; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Retinal Ganglion Cells | 2010 |
The EGCg-induced redox-sensitive activation of endothelial nitric oxide synthase and relaxation are critically dependent on hydroxyl moieties.
Topics: Animals; Catechin; Coronary Vessels; Endothelium, Vascular; Enzyme Activation; Hydrogen Peroxide; Nitric Oxide Synthase Type III; Oxidation-Reduction; Reactive Oxygen Species; Superoxides; Swine; Vasodilation | 2010 |
In vitro modulation of MMP-2 and MMP-9 in human cervical and ovarian cancer cell lines by cytokines, inducers and inhibitors.
Topics: Catechin; Cell Line, Tumor; Cytokines; Dose-Response Relationship, Drug; Doxycycline; Enzyme Induction; Female; Humans; Interleukin-1beta; Lipopolysaccharides; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Ovarian Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Uterine Cervical Neoplasms | 2010 |
Celastrol and an EGCG pro-drug exhibit potent chemosensitizing activity in human leukemia cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cytarabine; Daunorubicin; Fusion Proteins, bcr-abl; Humans; Leukemia; Molecular Structure; Pentacyclic Triterpenes; Plant Extracts; Prodrugs; Triterpenes | 2010 |
(-)-Epigallocatechin-3-gallate induces apoptosis and suppresses proliferation by inhibiting the human Indian Hedgehog pathway in human chondrosarcoma cells.
Topics: Anticarcinogenic Agents; Apoptosis; Bone Neoplasms; Catechin; Cell Death; Cell Division; Cell Survival; Chondrosarcoma; DNA Primers; Flow Cytometry; Gene Amplification; Humans; Patched Receptors; Patched-1 Receptor; Receptors, Cell Surface | 2010 |
Staphylococcal strains adapted to epigallocathechin gallate (EGCG) show reduced susceptibility to vancomycin, oxacillin and ampicillin, increased heat tolerance, and altered cell morphology.
Topics: Adaptation, Physiological; Ampicillin; Anti-Bacterial Agents; Catechin; Cell Wall; Drug Resistance, Multiple, Bacterial; Hot Temperature; Microbial Sensitivity Tests; Microscopy, Electron, Transmission; Oxacillin; Staphylococcus aureus; Vancomycin | 2010 |
Effects of cigarette smoke borne reactive nitrogen species on salivary alpha-amylase activity and protein modifications.
Topics: Catechin; Down-Regulation; Enzyme Activation; Female; Humans; Luminescent Measurements; Male; Nicotiana; Nitrosation; Protein Modification, Translational; Reactive Nitrogen Species; Saliva; Salivary alpha-Amylases; Smoke | 2009 |
Epigallocatechin-3-gallate (EGCG) attenuates inflammation in MRL/lpr mouse mesangial cells.
Topics: AMP-Activated Protein Kinases; Animals; Catechin; Cell Survival; Female; Inflammation; Interferon-gamma; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Mesangial Cells; Mice; Mice, Inbred MRL lpr; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases | 2010 |
(-)-Epigallocatechin-3-gallate downregulates Pg-P and BCRP in a tamoxifen resistant MCF-7 cell line.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; bcl-2-Associated X Protein; Breast Neoplasms; Camellia sinensis; Catechin; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression; Humans; Leupeptins; Mitoxantrone; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Plant Extracts; Protease Inhibitors; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Tamoxifen | 2010 |
Fifth complement cascade protein (C5) cleavage fragments disrupt the SDF-1/CXCR4 axis: further evidence that innate immunity orchestrates the mobilization of hematopoietic stem/progenitor cells.
Topics: Animals; Catechin; Cells, Cultured; Chemokine CXCL12; Chemotaxis; Complement C5; Complement C5a; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression Regulation; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Humans; Immunity, Innate; Lymphoma, Non-Hodgkin; Mice; Peptide Fragments; Receptor, Anaphylatoxin C5a; Receptors, CXCR4; Up-Regulation | 2010 |
Molecular mechanisms of green tea polyphenols.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis; Biological Availability; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Female; Flavonoids; Humans; Male; Methylation; Mice; Phenols; Polyphenols; Prodrugs; Proteasome Inhibitors; Rats; Tea; Ubiquitinated Proteins | 2009 |
Pro-oxidative activities and dose-response relationship of (-)-epigallocatechin-3-gallate in the inhibition of lung cancer cell growth: a comparative study in vivo and in vitro.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Deoxyguanosine; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Histones; Humans; Lung Neoplasms; Male; Membrane Potential, Mitochondrial; Mice; Oxidative Stress; Reactive Oxygen Species; Xenograft Model Antitumor Assays | 2010 |
The inhibition of collagenase induced degradation of collagen by the galloyl-containing polyphenols tannic acid, epigallocatechin gallate and epicatechin gallate.
Topics: Antioxidants; Catechin; Collagen; Collagenases; Extracellular Matrix; Flavonoids; Gallic Acid; Matrix Metalloproteinase Inhibitors; Phenols; Polyphenols; Tannins | 2010 |
Effects of oral epigallocatechin gallate on the pharmacokinetics of nicardipine in rats.
Topics: Administration, Oral; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Catechin; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Free Radical Scavengers; Half-Life; Injections, Intravenous; Male; Nicardipine; Rats; Rats, Sprague-Dawley | 2009 |
A multisampling reporter system for monitoring microRNA activity in the same population of cells.
Topics: Catechin; Genes, Reporter; Genetic Techniques; Hep G2 Cells; Humans; MicroRNAs | 2009 |
Effects of epigallocatechin gallate on regulatory T cell number and function in obese v. lean volunteers.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Blotting, Western; Camellia sinensis; Case-Control Studies; Catechin; Cell Culture Techniques; Enzyme-Linked Immunosorbent Assay; Epigenesis, Genetic; Female; Flow Cytometry; Forkhead Transcription Factors; Histone Deacetylases; Humans; Interleukin-10; Male; Middle Aged; Obesity; Phytotherapy; Plant Extracts; T-Lymphocytes, Regulatory; Thinness; Transcription Factor RelA; Young Adult | 2010 |
Tea catechins reduce inflammatory reactions via mitogen-activated protein kinase pathways in toll-like receptor 2 ligand-stimulated dental pulp cells.
Topics: Anti-Inflammatory Agents; Catechin; Cells, Cultured; Dental Pulp; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Humans; Inflammation; Inflammation Mediators; Ligands; Mitogen-Activated Protein Kinases; Phosphorylation; Receptors, Pattern Recognition; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Streptococcus; Tea; Toll-Like Receptor 2; Up-Regulation | 2010 |
Green tea polyphenol epigallocatechin gallate inhibits cell signaling by inducing SOCS1 gene expression.
Topics: Animals; Antioxidants; Catechin; Cells, Cultured; Gene Expression Profiling; Humans; Mice; Mice, Inbred C57BL; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Structure-Activity Relationship; Superoxides; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins; Tea; Up-Regulation | 2010 |
Polyphenol (-)-epigallocatechin gallate during ischemia limits infarct size via mitochondrial K(ATP) channel activation in isolated rat hearts.
Topics: Animals; Anti-Arrhythmia Agents; Antioxidants; Catechin; Decanoic Acids; Glyburide; Heart; Hemodynamics; Humans; Hydroxy Acids; KATP Channels; Male; Mitochondria, Heart; Myocardial Infarction; Myocardial Ischemia; Potassium Channel Blockers; Rats; Rats, Wistar | 2010 |
Low dosage of rasagiline and epigallocatechin gallate synergistically restored the nigrostriatal axis in MPTP-induced parkinsonism.
Topics: Animals; Antioxidants; Catechin; Cell Line; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Indans; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Neuroprotective Agents; Parkinsonian Disorders; Recovery of Function; Substantia Nigra; Treatment Outcome | 2010 |
Gels containing MMP inhibitors prevent dental erosion in situ.
Topics: Adult; Animals; Anti-Infective Agents, Local; Carbonated Beverages; Cariostatic Agents; Catechin; Cattle; Chlorhexidine; Dentin; Gels; Humans; Matrix Metalloproteinase Inhibitors; Microscopy, Electron, Scanning; Placebos; Protease Inhibitors; Sodium Fluoride; Time Factors; Tooth Erosion; Young Adult | 2010 |
Study of the release of gallic acid from (-)-epigallocatechin gallate in old oolong tea by mass spectrometry.
Topics: Catechin; Chromatography, Liquid; Dimerization; Gallic Acid; Models, Molecular; Spectrometry, Mass, Electrospray Ionization; Tea; Time Factors | 2010 |
New inhibitors for expression of IgE receptor on human mast cell.
Topics: Anthocyanins; Anti-Allergic Agents; Catechin; Cell Line; Flavones; Flavonoids; Gene Expression; Humans; Hypersensitivity; Mast Cells; Receptors, IgE | 2010 |
EGCG protects against oxidized LDL-induced endothelial dysfunction by inhibiting LOX-1-mediated signaling.
Topics: Catechin; Cells, Cultured; Endothelial Cells; Female; Humans; Infant, Newborn; Male; Oxidation-Reduction; Scavenger Receptors, Class E; Signal Transduction | 2010 |
Effect of green tea catechins and hydrolyzable tannins on benzo[a]pyrene-induced DNA adducts and structure-activity relationship.
Topics: Animals; Benzo(a)pyrene; Catechin; DNA; DNA Adducts; Hydrolyzable Tannins; Isotope Labeling; Microsomes, Liver; Rats; Structure-Activity Relationship; Tannins; Tea | 2010 |
Effects of the main green tea polyphenol epigallocatechin-3-gallate on cardiac involvement in patients with AL amyloidosis.
Topics: Aged; Amyloidosis; Catechin; Female; Humans; Male; Middle Aged; Plant Extracts; Tea; Treatment Outcome; Ventricular Dysfunction, Left | 2010 |
Nanochemoprevention by bioactive food components: a perspective.
Topics: Animals; Anticarcinogenic Agents; Catechin; Chemoprevention; Humans; Nanoparticles; Nanotechnology; Neoplasms | 2010 |
Anti-melanoma effects of vorinostat in combination with polyphenolic antioxidant (-)-epigallocatechin-3-gallate (EGCG).
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; eIF-2 Kinase; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Melanoma; NF-kappa B; Vorinostat | 2010 |
The major green tea polyphenol, (-)-epigallocatechin-3-gallate, induces heme oxygenase in rat neurons and acts as an effective neuroprotective agent against oxidative stress.
Topics: Animals; Antioxidants; Camellia sinensis; Catechin; Gene Expression Regulation; Heme Oxygenase-1; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Plant Extracts; Protoporphyrins; Rats; RNA, Messenger; Tea | 2009 |
Pancreatic cancer DNMT1 expression and sensitivity to DNMT1 inhibitors.
Topics: Azacitidine; Catechin; Cell Line, Tumor; Cell Proliferation; Chromosomes, Human, Pair 19; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Resistance, Neoplasm; Gene Dosage; Humans; Mutation; Pancreatic Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins | 2010 |
Use of different buffers for detection and separation in determination of physio-active components in oolong tea infusion by CZE with amperometric detection.
Topics: Amino Acids; Ascorbic Acid; Buffers; Carbohydrates; Catechin; Electrochemistry; Electrophoresis, Capillary; Limit of Detection; Reproducibility of Results; Tea | 2010 |
Evaluation of enoyl-acyl carrier protein reductase inhibitors as Pseudomonas aeruginosa quorum-quenching reagents.
Topics: Amino Acid Sequence; Biofilms; Catechin; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Green Fluorescent Proteins; Hydrogen Bonding; Indicators and Reagents; Molecular Dynamics Simulation; Molecular Sequence Data; Movement; Pseudomonas aeruginosa; Quorum Sensing; Sequence Alignment; Triclosan; Virulence | 2010 |
(-)-Epigallocatechin gallate inhibits growth and activation of the VEGF/VEGFR axis in human colorectal cancer cells.
Topics: Anticarcinogenic Agents; Caco-2 Cells; Catechin; Cell Line, Tumor; Colorectal Neoplasms; ErbB Receptors; HCT116 Cells; HT29 Cells; Humans; Vascular Endothelial Growth Factor A | 2010 |
Chitosan green tea polyphenol complex as a released control compound for wound healing.
Topics: Animals; Antioxidants; Catechin; Chitosan; Flavonoids; Hydrogen-Ion Concentration; Male; Phenols; Plant Extracts; Polyphenols; Rats; Tea; Wound Healing | 2010 |
(-)-Epigallocatechin-3-gallate inhibits Met signaling, proliferation, and invasiveness in human colon cancer cells.
Topics: Antineoplastic Agents; Catechin; Cell Proliferation; Cell Survival; Colonic Neoplasms; HCT116 Cells; Hepatocyte Growth Factor; Humans; Indoles; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Receptors, Growth Factor; Signal Transduction; Sulfonamides; Tea | 2010 |
[Theanine, EGCG and caffeine determinated by HPLC].
Topics: Caffeine; Catechin; Chromatography, High Pressure Liquid; Glutamates; Sensitivity and Specificity; Tea | 2010 |
Bioactive dietary polyphenols decrease heme iron absorption by decreasing basolateral iron release in human intestinal Caco-2 cells.
Topics: Absorption; Biological Transport; Caco-2 Cells; Catechin; Flavonoids; Grape Seed Extract; Heme; Humans; Intestines; Iron; Phenols; Polyphenols | 2010 |
Effects of (-)-epigallocatechin gallate on RPE cell migration and adhesion.
Topics: Actins; Becaplermin; Catechin; Cell Adhesion; Cell Movement; Cytoskeleton; Electric Impedance; Epithelial Cells; Fibronectins; Humans; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-sis; Receptor, Platelet-Derived Growth Factor beta; Retinal Pigment Epithelium; Time Factors | 2010 |
Epimerization of tea catechins under weakly acidic and alkaline conditions.
Topics: Acids; Catechin; Molecular Conformation | 2010 |
Epigallocatechin gallate inhibits beta amyloid oligomerization in Caenorhabditis elegans and affects the daf-2/insulin-like signaling pathway.
Topics: Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Antioxidants; Biological Transport; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Camellia sinensis; Catechin; Cell Nucleus; Cytoplasm; Heat-Shock Proteins; Insulin; Lipofuscin; Naphthoquinones; Oxidative Stress; Plant Extracts; Polymerization; Receptor, Insulin; Signal Transduction; Somatomedins; Transcription Factors | 2010 |
EGCG remodels mature alpha-synuclein and amyloid-beta fibrils and reduces cellular toxicity.
Topics: alpha-Synuclein; Amyloid; Amyloid beta-Peptides; Amyloid Neuropathies; Animals; Blotting, Western; Catechin; CHO Cells; Chromatography, Affinity; Circular Dichroism; Cricetinae; Cricetulus; Escherichia coli; Humans; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Neuroprotective Agents; PC12 Cells; Rats | 2010 |
General synthesis of epi-series catechins and their 3-gallates: reverse polarity strategy.
Topics: Antioxidants; Catechin; Chemistry, Organic; Cyclization; Gallic Acid | 2010 |
[The antagonistic action of epigallocatechin-3-gallate on microcystin LR-induced oxidative damage on hepatocytes of mice and the expression of cytochrome P450 2E1].
Topics: Animals; Catechin; Cytochrome P-450 CYP2E1; Hepatocytes; Male; Marine Toxins; Mice; Mice, Inbred BALB C; Microcystins; Oxidative Stress | 2010 |
The functional effect of epigallocatechin gallate on ischemic stroke in rats.
Topics: Animals; Behavior, Animal; Brain Infarction; Catechin; Disease Models, Animal; Hindlimb; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sensory Gating; Statistics, Nonparametric | 2010 |
[Effect of epigallocatechin-3-galate on human acute monocytic leukemia cell line U937 and its relevant mechanism].
Topics: Catechin; Cell Proliferation; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Gene Expression Regulation, Leukemic; Genes, p16; Humans; Leukemia, Monocytic, Acute; U937 Cells | 2010 |
Epigallocatechin-3-gallate ameliorates hyperglycemia-induced embryonic vasculopathy and malformation by inhibition of Foxo3a activation.
Topics: Animals; Antioxidants; Blotting, Western; Catechin; Disease Models, Animal; Embryonic Development; Female; Fetus; Forkhead Box Protein O3; Forkhead Transcription Factors; Hyperglycemia; In Vitro Techniques; Oxidative Stress; Phosphorylation; Pregnancy; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Yolk Sac | 2010 |
Inhibition of the insulin-like growth factor I receptor by epigallocatechin gallate blocks proliferation and induces the death of Ewing tumor cells.
Topics: Anticarcinogenic Agents; Apoptosis; Bone Neoplasms; Catechin; Cell Adhesion; Cell Death; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Drug Evaluation, Preclinical; Humans; MAP Kinase Signaling System; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphorylation; Receptor, IGF Type 1; Sarcoma, Ewing | 2010 |
Epigallocatechin gallate suppresses lung cancer cell growth through Ras-GTPase-activating protein SH3 domain-binding protein 1.
Topics: Anticarcinogenic Agents; Blotting, Western; Carrier Proteins; Catechin; Cell Line, Tumor; Cell Proliferation; DNA Helicases; Humans; Immunoprecipitation; Lung Neoplasms; Poly-ADP-Ribose Binding Proteins; RNA Helicases; RNA Recognition Motif Proteins; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; src Homology Domains | 2010 |
Effects of catechin, epicatechin and epigallocatechin gallate on testosterone production in rat leydig cells.
Topics: Animals; Blotting, Western; Catechin; Electrophoresis, Polyacrylamide Gel; Leydig Cells; Male; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Testosterone | 2010 |
Extraordinary anticancer effect of green tea and red light.
Topics: Anticarcinogenic Agents; Catechin; Cell Proliferation; Dose-Response Relationship, Drug; HeLa Cells; Humans; Laser Therapy | 2010 |
Epigallocatechin-3-gallate (EGCG) reduces liver inflammation, oxidative stress and fibrosis in carbon tetrachloride (CCl4)-induced liver injury in mice.
Topics: Actins; Animals; Anti-Inflammatory Agents; Carbon Tetrachloride; Catechin; Chemical and Drug Induced Liver Injury; Collagen Type I; Cyclooxygenase 2 Inhibitors; Liver Cirrhosis; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Oxidative Stress; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Tyrosine | 2010 |
Plasma tea polyphenol levels and subsequent risk of breast cancer among Japanese women: a nested case-control study.
Topics: Adult; Aged; Asian People; Breast Neoplasms; Case-Control Studies; Catechin; Female; Flavonoids; Humans; Japan; Logistic Models; Middle Aged; Odds Ratio; Phenols; Polyphenols; Prospective Studies; Risk Assessment; Risk Factors; Surveys and Questionnaires; Tea; Time Factors | 2010 |
Cross-linked agarose for separation of low molecular weight natural products in hydrophilic interaction liquid chromatography.
Topics: Acetonitriles; Adsorption; Catechin; Chromatography, Liquid; Fallopia japonica; Flavonoids; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Microscopy, Electron, Scanning; Phenols; Plant Extracts; Plant Roots; Polyphenols; Salvia miltiorrhiza; Sepharose; Tea | 2010 |
Probing the antioxidant activity of polyphenols by CIDNP: from model compounds to green tea and red wine.
Topics: Antioxidants; Catechin; Flavonoids; Molecular Structure; Phenols; Polyphenols; Spectrum Analysis; Tea; Wine | 2010 |
p53-Dependent p21-mediated growth arrest pre-empts and protects HCT116 cells from PUMA-mediated apoptosis induced by EGCG.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Apoptosis Regulatory Proteins; Catechin; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Genes, p53; HCT116 Cells; Humans; Proto-Oncogene Proteins; Transfection; Tumor Suppressor Protein p53 | 2010 |
PKC-delta and -eta, MEKK-1, MEK-6, MEK-3, and p38-delta are essential mediators of the response of normal human epidermal keratinocytes to differentiating agents.
Topics: Anticarcinogenic Agents; Calcium; Carcinogens; Catechin; Cell Differentiation; Cells, Cultured; Epidermal Cells; Humans; Keratinocytes; MAP Kinase Kinase 3; MAP Kinase Kinase 6; MAP Kinase Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 13; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C-delta; Protein Precursors; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2010 |
(-)-Epigallocatechin-3-gallate down-regulates EGFR, MMP-2, MMP-9 and EMMPRIN and inhibits the invasion of MCF-7 tamoxifen-resistant cells.
Topics: Basigin; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drug Resistance, Neoplasm; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Phosphorylation; RNA, Messenger; Signal Transduction; Tamoxifen; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2 | 2011 |
Suppression mechanisms of flavonoids on aryl hydrocarbon receptor-mediated signal transduction.
Topics: Active Transport, Cell Nucleus; Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Base Sequence; Catechin; Cell Line, Tumor; DNA Primers; Flavanones; Flavonoids; MAP Kinase Signaling System; Mice; Phosphorylation; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Recombinant Proteins; Signal Transduction; Transfection | 2010 |
Green tea epigallocatechin gallate inhibits insulin stimulation of adipocyte glucose uptake via the 67-kilodalton laminin receptor and AMP-activated protein kinase pathways.
Topics: AMP-Activated Protein Kinases; Animals; Catechin; Glucose; Insulin; Mice; Mice, Inbred C3H; NIH 3T3 Cells; Receptors, Laminin; Tea | 2010 |
[Effect of epigallocatechin-3-gallate on the activity of alpha-glucosidase in vitro].
Topics: alpha-Glucosidases; Animals; Catechin; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Intestinal Mucosa; Intestine, Small; Rats; Rats, Wistar; Yeasts | 2010 |
[Effects of differentially expressed proteins in hepatocellular carcinoma cell treated by different telomerase inhibitors].
Topics: Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Enzyme Inhibitors; Humans; Liver Neoplasms; Protein Array Analysis; Proteome; Telomerase; Tretinoin; Zidovudine | 2010 |
Tea polyphenols inhibit IL-6 production in tumor necrosis factor superfamily 14-stimulated human gingival fibroblasts.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biflavonoids; Catechin; Cells, Cultured; Chronic Periodontitis; Enzyme Inhibitors; Female; Fibroblasts; Flavonoids; Gallic Acid; Gene Expression Regulation; Gingiva; Humans; Interleukin-6; Male; Middle Aged; Phenols; Polyphenols; RNA, Messenger; Signal Transduction; Tea; Tumor Necrosis Factor Ligand Superfamily Member 14 | 2010 |
Effects of epigallocatechin-3-gallate on behavioral impairments induced by psychological stress in rats.
Topics: Animals; Behavior, Animal; Catechin; Catecholamines; Gene Expression Regulation; Hippocampus; Hydrocortisone; Interleukin-2; Interleukin-6; Male; Metallothionein; Phytotherapy; Rats; Rats, Wistar; Serotonin; Stress, Psychological | 2010 |
Neuroprotective effects of Epigallocatechin-3-gallate (EGCG) in optic nerve crush model in rats.
Topics: Animals; Catechin; Cell Count; Cell Survival; Disease Models, Animal; Female; Nerve Crush; Neurofilament Proteins; Neuroprotective Agents; Optic Nerve Injuries; Random Allocation; Rats; Rats, Wistar; Retina; Retinal Ganglion Cells; Time Factors; Treatment Outcome | 2010 |
Dietary catechins and procyanidins modulate zinc homeostasis in human HepG2 cells.
Topics: Biflavonoids; Carcinoma, Hepatocellular; Catechin; Cation Transport Proteins; Diet; Gene Expression Regulation; Grape Seed Extract; Hep G2 Cells; Homeostasis; Humans; Interleukin-6; Liver Neoplasms; Metallothionein; Proanthocyanidins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tea; Zinc | 2011 |
Green tea catechins are potent sensitizers of ryanodine receptor type 1 (RyR1).
Topics: Action Potentials; Adult; Anticarcinogenic Agents; Antioxidants; Apoptosis; Catechin; Humans; Neurons; Plant Extracts; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Signal Transduction; Structure-Activity Relationship; Synaptic Transmission; Tea | 2010 |
Antimicrobial activity of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) against clinical isolates of Stenotrophomonas maltophilia.
Topics: Anti-Bacterial Agents; Camellia sinensis; Catechin; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Stenotrophomonas maltophilia | 2010 |
Epigallocatechin-3-gallate protects Na+ channels in rat ventricular myocytes against sulfite.
Topics: Animals; Catalase; Catechin; Cell Separation; Electrophysiology; Glutathione Peroxidase; Hydrogen Peroxide; Hydroxyl Radical; Myocytes, Cardiac; Oxidative Stress; Patch-Clamp Techniques; Rats; Reactive Oxygen Species; Sodium Channels; Sulfites; Superoxide Dismutase; Superoxides | 2010 |
Cloning of a novel O-methyltransferase from Camellia sinensis and synthesis of o-methylated EGCG and evaluation of their bioactivity.
Topics: Amino Acid Sequence; Animals; Anti-Allergic Agents; Anti-Bacterial Agents; Bone Marrow Cells; Camellia sinensis; Catechin; Cloning, Molecular; Free Radical Scavengers; Histamine Release; Mice; Molecular Sequence Data; Plant Proteins; Protein O-Methyltransferase; Sequence Alignment | 2010 |
Inhibition of proliferation and gene expression regulation by (-)-epigallocatechin-3-gallate in human synovial sarcoma cells.
Topics: Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Separation; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Proto-Oncogene Proteins c-bcl-2; Sarcoma, Synovial | 2011 |
In vitro electrocardiographic and cardiac ion channel effects of (-)-epigallocatechin-3-gallate, the main catechin of green tea.
Topics: Animals; Calcium Channels, L-Type; Catechin; CHO Cells; Cricetinae; Cricetulus; Electrocardiography; Guinea Pigs; Heart; Humans; In Vitro Techniques; Ion Channel Gating; Ion Channels; Patch-Clamp Techniques; Potassium Channels; Sodium Channels; Stereoisomerism; Tea | 2010 |
Anti-inflammatory effect of catechin on cultured human dental pulp cells affected by bacteria-derived factors.
Topics: Anti-Inflammatory Agents; Antioxidants; Catechin; Cells, Cultured; Dental Pulp; Escherichia coli; Flow Cytometry; Humans; Intercellular Adhesion Molecule-1; Interleukin-6; Interleukin-8; Lipopolysaccharides; Peptidoglycan; Reverse Transcriptase Polymerase Chain Reaction; Staphylococcus aureus; Time Factors; Vascular Cell Adhesion Molecule-1 | 2010 |
Epigallocatechin-3-gallate protects motor neurons and regulates glutamate level.
Topics: Animals; Blotting, Western; Catechin; Gene Expression Regulation; Glutamic Acid; Immunohistochemistry; Motor Neurons; Neuroprotective Agents; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Spinal Cord | 2010 |
Effect of epigallocatechin-3-gallate on iron overload in mice with alcoholic liver disease.
Topics: Animals; Antimicrobial Cationic Peptides; Catechin; Hepcidins; Iron; Iron Overload; Liver; Liver Diseases, Alcoholic; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Models, Biological; Receptors, Transferrin; Reverse Transcriptase Polymerase Chain Reaction; Transferrin | 2011 |
Green and black tea inhibit cytokine-induced IL-8 production and secretion in AGS gastric cancer cells via inhibition of NF-κB activity.
Topics: Camellia sinensis; Catechin; Cell Line, Tumor; Chromatography, Liquid; Humans; Interleukin-1beta; Interleukin-8; MAP Kinase Signaling System; Mass Spectrometry; NF-kappa B; Plant Extracts; Stomach Neoplasms; Tea | 2010 |
Epigallocatechin-3-gallate inhibits mast cell degranulation, leukotriene C4 secretion, and calcium influx via mitochondrial calcium dysfunction.
Topics: Animals; Calcium; Catechin; Leukotriene C4; Mast Cells; Mice; Mice, Inbred C57BL; Mitochondria; Rats; Reactive Oxygen Species | 2010 |
TLR4 signaling inhibitory pathway induced by green tea polyphenol epigallocatechin-3-gallate through 67-kDa laminin receptor.
Topics: Animals; Catechin; Cell Line; Down-Regulation; Gene Expression Regulation; Humans; Inflammation Mediators; Intracellular Signaling Peptides and Proteins; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Molecular Weight; Protein Transport; Receptors, Laminin; Signal Transduction; Toll-Like Receptor 4 | 2010 |
Epigallocatechin gallate-induced modulation of FoxO signaling in mammalian cells and C. elegans: FoxO stimulation is masked via PI3K/Akt activation by hydrogen peroxide formed in cell culture.
Topics: Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Catechin; Cell Line; Dyrk Kinases; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression; Genes, Helminth; Harmine; Humans; Hydrogen Peroxide; Longevity; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Superoxide Dismutase; Transcription Factors | 2010 |
Theaflavin digallate inactivates plasminogen activator inhibitor: could tea help in Alzheimer's disease and obesity?
Topics: Alzheimer Disease; Biflavonoids; Catechin; Electrophoresis, Polyacrylamide Gel; Gallic Acid; Humans; Indoleacetic Acids; Mutation; Obesity; Plasminogen Activator Inhibitor 1; Protein Binding; Tea; Thrombelastography; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator | 2010 |
EGCG and quercetin protected INS-1 cells in oxidative stress via different mechanisms.
Topics: Animals; Antioxidants; Blotting, Western; Catechin; Cell Line; Enzyme-Linked Immunosorbent Assay; Oxidative Stress; Quercetin; Rats; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
Reciprocal relationship between cytosolic NADH and ENOX2 inhibition triggers sphingolipid-induced apoptosis in HeLa cells.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cell Survival; Ceramides; Chromatography, Thin Layer; Cytosol; Dose-Response Relationship, Drug; HeLa Cells; Humans; Isoflavones; Lysophospholipids; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; Phosphotransferases (Alcohol Group Acceptor); Sphingolipids; Sphingomyelin Phosphodiesterase; Sphingosine | 2010 |
Beneficial effect of dietary epigallocatechin-3-gallate on skin via enhancement of antioxidant capacity in both blood and skin.
Topics: Animals; Antioxidants; Blood; Catechin; Diet; Female; Radiation-Protective Agents; Rats; Rats, Hairless; Skin; Ultraviolet Rays; Water Loss, Insensible | 2010 |
Biological and biomechanical evaluations of osteochondral allografts preserved in cold storage solution containing epigallocatechin gallate.
Topics: Aged; Biomechanical Phenomena; Cartilage, Articular; Catechin; Cell Survival; Chondrocytes; Cryopreservation; Extracellular Matrix; Humans; Menisci, Tibial; Middle Aged; Organ Preservation; Organ Preservation Solutions; Transplantation, Homologous | 2010 |
Epigallocatechin-3-gallate (EGCG) downregulates gelatinase-B (MMP-9) by involvement of FAK/ERK/NFkappaB and AP-1 in the human breast cancer cell line MDA-MB-231.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Carrier Proteins; Catechin; Cell Line, Tumor; Cell Movement; Cell Survival; Down-Regulation; Extracellular Matrix Proteins; Extracellular Signal-Regulated MAP Kinases; Female; Focal Adhesion Protein-Tyrosine Kinases; Humans; Matrix Metalloproteinase 9; NF-kappa B; RNA, Messenger; Signal Transduction; Tissue Inhibitor of Metalloproteinase-1; Transcription Factor AP-1 | 2010 |
Epigallocatechin-3-gallate ameliorates alcohol-induced cognitive dysfunctions and apoptotic neurodegeneration in the developing rat brain.
Topics: Animals; Animals, Newborn; Apoptosis; Brain; Catechin; Cognition Disorders; Ethanol; Male; Maze Learning; Neurodegenerative Diseases; Random Allocation; Rats; Rats, Wistar | 2010 |
Epigallocatechin-3-gallate directly suppresses T cell proliferation through impaired IL-2 utilization and cell cycle progression.
Topics: Animals; Antibodies, Monoclonal; Catechin; CD28 Antigens; CD3 Complex; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Cycle; Cell Division; Gene Expression; Interleukin-2; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Receptors, Interleukin-2; RNA, Messenger; Spleen; T-Lymphocytes | 2010 |
Epigallocatechin-3-gallate suppresses the expression of HSP70 and HSP90 and exhibits anti-tumor activity in vitro and in vivo.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents, Phytogenic; Binding Sites; Breast Neoplasms; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Male; Mice; Mice, Inbred BALB C; Oxidative Stress; Promoter Regions, Genetic; Time Factors; Transcription, Genetic; Transfection; Tumor Burden | 2010 |
Inhibition of inducible nitric oxide synthase expression and cell death by (-)-epigallocatechin-3-gallate, a green tea catechin, in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
Topics: Animals; Catechin; Cell Death; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nitric Oxide Synthase Type II; Parkinsonian Disorders; Tea | 2010 |
(-)-Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, reduces dichlorodiphenyl-trichloroethane (DDT)-induced cell death in dopaminergic SHSY-5Y cells.
Topics: Catechin; Cell Death; Cell Line, Tumor; Cell Survival; DDT; Dopamine; Humans; Neuroblastoma; Neuroprotective Agents; Pesticides | 2010 |
Inhibition by flavonoids of amyloid-like fibril formation by Plasmodium falciparum merozoite surface protein 2.
Topics: Amyloid; Animals; Antigens, Protozoan; Catechin; Child; Flavonoids; Humans; Magnetic Resonance Spectroscopy; Malaria Vaccines; Membrane Proteins; Merozoites; Plasmodium falciparum; Protozoan Proteins | 2010 |
Oral pretreatment with a green tea polyphenol for cardioprotection against ischemia-reperfusion injury in an isolated rat heart model.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Animals; Antioxidants; Apoptosis; Blotting, Western; Camellia sinensis; Cardiotonic Agents; Caspase 3; Catechin; Deoxyguanosine; Dose-Response Relationship, Drug; Enzyme Activation; Immunohistochemistry; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Perfusion; Rats; Rats, Sprague-Dawley; Time Factors; Ventricular Function, Left; Ventricular Pressure | 2011 |
Epigallocatechin gallate protects H9c2 cardiomyoblasts against hydrogen dioxides- induced apoptosis and telomere attrition.
Topics: Animals; Antioxidants; Apoptosis; Cardiotonic Agents; Catechin; Cell Line; Cells, Cultured; DNA Fragmentation; Dose-Response Relationship, Drug; Embryo, Mammalian; Flavonoids; Hydrogen Peroxide; Myoblasts, Cardiac; Myocytes, Cardiac; Oxidative Stress; Phenols; Polyphenols; Rats; Signal Transduction; Telomere; Time Factors | 2010 |
Candidate dietary phytochemicals modulate expression of phase II enzymes GSTP1 and NQO1 in human lung cells.
Topics: Anticarcinogenic Agents; Brassica; Bronchi; Camellia sinensis; Catechin; Cell Division; Cell Line; Cell Line, Tumor; Epithelial Cells; Gene Expression; Glutathione S-Transferase pi; Humans; Isothiocyanates; Lung; Lung Neoplasms; NAD(P)H Dehydrogenase (Quinone); Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfoxides; Thiocyanates | 2010 |
Robinetinidol-(4beta-->8)-epigallocatechin 3-O-gallate, a galloyl dimer prorobinetinidin from Acacia mearnsii De Wild, effectively protects human neuroblastoma SH-SY5Y cells against acrolein-induced oxidative damage.
Topics: Acacia; Acrolein; Caspase 3; Catechin; Cell Line, Tumor; Cell Survival; Dimerization; Flavonoids; Humans; Lipid Peroxidation; NADPH Oxidases; Nerve Degeneration; Neuroblastoma; Neurons; Neuroprotective Agents; Oxidative Stress | 2010 |
Protective effects of polyphenolic compounds on oxidative stress-induced cytotoxicity in PC12 cells.
Topics: Animals; Antioxidants; Catechin; Cell Survival; Cobalt; Flavonoids; Gallic Acid; Glutathione; Hydrogen Peroxide; Nitric Oxide; Oxidative Stress; PC12 Cells; Phenols; Polyphenols; Protective Agents; Rats; Reactive Oxygen Species | 2010 |
The crystal structure of the green tea polyphenol (-)-epigallocatechin gallate-transthyretin complex reveals a novel binding site distinct from the thyroxine binding site.
Topics: Amyloid Neuropathies, Familial; Binding Sites; Camellia sinensis; Catechin; Crystallography, X-Ray; Flavonoids; Humans; Phenols; Polyphenols; Prealbumin; Protein Conformation; Thyroxine | 2010 |
Effects of epigallocatechin gallate, L-ascorbic acid, alpha-tocopherol, and dihydrolipoic acid on the formation of deoxyguanosine adducts derived from lipid peroxidation.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acrolein; alpha-Tocopherol; Antioxidants; Ascorbic Acid; Catechin; Deoxyguanosine; DNA Damage; Docosahexaenoic Acids; Lipid Peroxidation; Thioctic Acid | 2010 |
Epigallocatechin gallate-mediated protection against tumor necrosis factor-α-induced monocyte chemoattractant protein-1 expression is heme oxygenase-1 dependent.
Topics: Animals; Bilirubin; Catechin; Cells, Cultured; Chemokine CCL2; Cytoprotection; Endothelial Cells; Gene Expression; Heme Oxygenase-1; Inflammation; Oligodeoxyribonucleotides, Antisense; Swine; Transfection; Tumor Necrosis Factor-alpha; Up-Regulation | 2010 |
Advanced glycation end products-induced apoptosis attenuated by PPARdelta activation and epigallocatechin gallate through NF-kappaB pathway in human embryonic kidney cells and human mesangial cells.
Topics: Apoptosis; Catechin; Cell Survival; Cells, Cultured; Glycation End Products, Advanced; Humans; Interleukin-6; Kidney; Mesangial Cells; NF-kappa B; Oxidative Stress; Phenoxyacetates; PPAR delta; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Tumor Necrosis Factor-alpha | 2010 |
The interactions of epigallocatechin-3-gallate with human whole saliva and parotid saliva.
Topics: Adsorption; Adult; Astringents; Catechin; Chemical Precipitation; Elasticity; Entropy; Female; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Immobilized Proteins; Lubrication; Male; Middle Aged; Parotid Gland; Protease Inhibitors; Protein Binding; Saliva; Salivary Glands; Salivary Proteins and Peptides; Spectroscopy, Fourier Transform Infrared; Temperature; Urokinase-Type Plasminogen Activator; Viscosity; Young Adult | 2010 |
Computational modeling of the potential interactions of the proteasome beta5 subunit and catechol-O-methyltransferase-resistant EGCG analogs.
Topics: Catechin; Catechol O-Methyltransferase Inhibitors; Computer Simulation; Fungal Proteins; Models, Molecular; Molecular Conformation; Proteasome Endopeptidase Complex; Protein Binding; Protein Interaction Mapping; Thermodynamics | 2010 |
Inhibition of catechol-Omicron-methyltransferase activity in human breast cancer cells enhances the biological effect of the green tea polyphenol (-)-EGCG.
Topics: Apoptosis; Breast Neoplasms; Carcinoma; Catechin; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cell Proliferation; Drug Evaluation, Preclinical; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Female; Flavonoids; Humans; Phenols; Polyphenols; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Tea; Tumor Cells, Cultured | 2010 |
(-)-Epigallocatechin-3-O-gallate (EGCG) reverses caffeine-induced anxiogenic-like effects.
Topics: Animals; Anxiety; Caffeine; Catechin; Central Nervous System Stimulants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Male; Maze Learning; Mice; Mice, Inbred ICR; Neuroprotective Agents; Rats; Rats, Wistar; Spectrum Analysis | 2010 |
Chitosan nanoparticles enhance the intestinal absorption of the green tea catechins (+)-catechin and (-)-epigallocatechin gallate.
Topics: Animals; Biological Availability; Catechin; Chitosan; Chromatography, High Pressure Liquid; In Vitro Techniques; Intestinal Absorption; Male; Mice; Nanoparticles; Tea | 2010 |
Apoptotic effect of green tea polyphenol (EGCG) on cervical carcinoma cells.
Topics: Adenocarcinoma; Antioxidants; Apoptosis; Caspase 3; Catechin; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Leukocytes, Mononuclear; Uterine Cervical Neoplasms | 2011 |
Epigallocatechin-3-gallate activates Nrf2/HO-1 signaling pathway in cisplatin-induced nephrotoxicity in rats.
Topics: Aldehydes; Animals; Antineoplastic Agents; Antioxidants; Catalase; Catechin; Cisplatin; Glutathione; Glutathione Peroxidase; Heme Oxygenase-1; Kidney; Male; Neoplasms; NF-E2-Related Factor 2; NF-kappa B; Rats; Rats, Wistar; Signal Transduction; Superoxide Dismutase; Tea | 2010 |
The polyphenol epigallocatechin-3-gallate affects lipid rafts to block activation of the c-Met receptor in prostate cancer cells.
Topics: Anticarcinogenic Agents; Antioxidants; beta-Cyclodextrins; Catechin; Cell Movement; Cells; Flavonoids; Humans; Male; Octoxynol; Phenols; Phosphatidylinositol 3-Kinases; Phosphorylation; Polyphenols; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction; Tea | 2010 |
Modulation of collagen type I, fibronectin and dermal fibroblast function and activity, in systemic sclerosis by the antioxidant epigallocatechin-3-gallate.
Topics: Analysis of Variance; Antioxidants; Biopsy; Case-Control Studies; Catechin; Cells, Cultured; Collagen Type I; Extracellular Matrix; Female; Fibroblasts; Fibronectins; Humans; Reactive Oxygen Species; Scleroderma, Systemic | 2010 |
Epigallocatechin gallate inhibits angiotensin II-induced endothelial barrier dysfunction via inhibition of the p38 MAPK/HSP27 pathway.
Topics: Angiotensin II; Catechin; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; HSP27 Heat-Shock Proteins; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Signal Transduction; Stress Fibers; Umbilical Veins | 2010 |
Underlying mechanism for suppression of vascular smooth muscle cells by green tea polyphenol EGCG released from biodegradable polymers for stent application.
Topics: Animals; Antioxidants; Aorta; Apoptosis; Biocompatible Materials; Catechin; Cell Adhesion; Cell Cycle; Cell Proliferation; Cells, Cultured; Dogs; Male; Materials Testing; Matrix Metalloproteinase 2; Molecular Structure; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Polymers; Proto-Oncogene Proteins c-akt; Stents | 2010 |
Preventive effects of C-2 epimeric isomers of tea catechins on mouse type I allergy.
Topics: Abdominal Wall; Allergens; Animals; Anti-Allergic Agents; Catechin; Dose-Response Relationship, Immunologic; Hypersensitivity, Immediate; Immunoglobulin E; Interleukin-10; Interleukin-4; Isomerism; Male; Mice; Ovalbumin; Tea | 2010 |
Nutraceutical inhibition of muscle proteolysis: a role of diallyl sulphide in the treatment of muscle wasting.
Topics: Allyl Compounds; Animals; Anorexia; Cachexia; Catechin; Cells, Cultured; Dietary Supplements; Genistein; Male; Muscle, Skeletal; Muscular Atrophy; Neoplasms; Rats; Rats, Wistar; Resveratrol; Stilbenes; Sulfides; Weight Loss | 2011 |
The preventive effect of oral EGCG in a fetal alcohol spectrum disorder mouse model.
Topics: Animals; Blotting, Western; Brain; Catechin; Central Nervous System Depressants; Embryonic Development; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Fetus; Genetic Markers; Humans; Hydrogen Peroxide; Infant, Newborn; Malondialdehyde; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuroprotective Agents; Oxidative Stress; Pregnancy; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Tea | 2010 |
Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines.
Topics: Antineoplastic Agents, Phytogenic; Ascorbic Acid; Camellia sinensis; Catechin; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Lysine; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Micronutrients; Neoplasm Invasiveness; Neoplasms; Plant Extracts; Proline; Protease Inhibitors; Tetradecanoylphorbol Acetate | 2010 |
In vitro mechanism of action for the cytotoxicity elicited by the combination of epigallocatechin gallate and raloxifene in MDA-MB-231 cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Catechin; Cell Line, Tumor; ErbB Receptors; Estrogen Receptor alpha; Female; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Raloxifene Hydrochloride; Receptor, ErbB-2; Ribosomal Protein S6 Kinases; Selective Estrogen Receptor Modulators; Signal Transduction; Time Factors; TOR Serine-Threonine Kinases; Transcription Factor RelA | 2010 |
Ability of a salivary intrinsically unstructured protein to bind different tannin targets revealed by mass spectrometry.
Topics: Catechin; Humans; Molecular Structure; Protein Binding; Salivary Proline-Rich Proteins; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tannins | 2010 |
A major green tea component, (-)-epigallocatechin-3-gallate, ameliorates doxorubicin-mediated cardiotoxicity in cardiomyocytes of neonatal rats.
Topics: Animals; Animals, Newborn; Antineoplastic Agents; Catalase; Catechin; Doxorubicin; Glutathione Peroxidase; L-Lactate Dehydrogenase; Malondialdehyde; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tea | 2010 |
Inhibitory effects of commonly used herbal extracts on UGT1A1 enzyme activity.
Topics: Catechin; Drug Evaluation, Preclinical; Echinacea; Estradiol; Glucuronosyltransferase; Humans; Inhibitory Concentration 50; Microsomes, Liver; Plant Extracts; Serenoa; Silybum marianum | 2010 |
White tea extract induces apoptosis in non-small cell lung cancer cells: the role of peroxisome proliferator-activated receptor-{gamma} and 15-lipoxygenases.
Topics: Anilides; Apoptosis; Arachidonate 15-Lipoxygenase; Carcinoma, Non-Small-Cell Lung; Catechin; Drug Evaluation, Preclinical; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Hormone Antagonists; Humans; Hydroxyeicosatetraenoic Acids; Lung Neoplasms; Plant Extracts; PPAR gamma; Tea; Tumor Cells, Cultured | 2010 |
In vitro screening for angiostatic potential of herbal chemicals.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevacizumab; Blotting, Western; Catechin; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Chalcones; Drug Evaluation, Preclinical; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Eye Proteins; Focal Adhesion Protein-Tyrosine Kinases; Humans; Nerve Growth Factors; Plant Preparations; Resveratrol; Retinal Pigment Epithelium; Serpins; Stilbenes; Umbilical Veins; Vascular Endothelial Growth Factor A; Xanthones | 2010 |
(-)-Epigallocatechin-3-gallate (EGCG) post-transcriptionally and post-translationally suppresses the cell proliferative protein TROP2 in human colorectal cancer cells.
Topics: Anticarcinogenic Agents; Antigens, Neoplasm; Antioxidants; Catechin; Cell Adhesion Molecules; Colorectal Neoplasms; Dose-Response Relationship, Drug; HCT116 Cells; HT29 Cells; Humans; Protein Biosynthesis; Protein Processing, Post-Translational; RNA, Messenger | 2010 |
Epigallocatechin-3-gallate, a natural polyphenol, inhibits cell proliferation and induces apoptosis in human ovarian cancer cells.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Cell Survival; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Humans; In Situ Nick-End Labeling; Ovarian Neoplasms | 2010 |
Carbonyl reductase 1 as a novel target of (-)-epigallocatechin gallate against hepatocellular carcinoma.
Topics: Alcohol Oxidoreductases; Animals; Antibiotics, Antineoplastic; Anticarcinogenic Agents; Carcinoma, Hepatocellular; Catechin; Daunorubicin; Humans; Liver Neoplasms; Mice; Tumor Cells, Cultured | 2010 |
Green tea compound in chemoprevention of cervical cancer.
Topics: Apoptosis; Blotting, Western; Catechin; Cell Cycle; Cell Proliferation; Cells, Cultured; Cervix Uteri; Female; Human papillomavirus 16; Humans; Immunoenzyme Techniques; Papillomavirus E7 Proteins; Papillomavirus Infections; Tea; Uterine Cervical Neoplasms | 2010 |
AMP kinase acts as a negative regulator of RANKL in the differentiation of osteoclasts.
Topics: Adenylate Kinase; Animals; Apoptosis; Blotting, Western; Bone Resorption; Catechin; Cell Differentiation; Cell Survival; Cells, Cultured; Macrophage Colony-Stimulating Factor; MAP Kinase Kinase Kinases; Metformin; Mice; Mice, Inbred ICR; Osteoclasts; Osteogenesis; Pyrazoles; Pyrimidines; RANK Ligand; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Stilbenes | 2010 |
Natural products as DNA methyltransferase inhibitors: a computer-aided discovery approach.
Topics: Biological Products; Catechin; Computational Biology; Computer Simulation; Curcumin; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Design; Enzyme Inhibitors; HCT116 Cells; HEK293 Cells; HL-60 Cells; Humans; Models, Molecular; User-Computer Interface | 2011 |
Amelioration of functional, biochemical and molecular deficits by epigallocatechin gallate in experimental model of alcoholic neuropathy.
Topics: Alcoholic Neuropathy; Analysis of Variance; Animals; Behavior, Animal; Catechin; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Hyperalgesia; Male; Oxidative Stress; Physical Stimulation; Rats; Rats, Wistar; Urokinase-Type Plasminogen Activator | 2011 |
(-)-Epigallocatethin-3-O-gallate counteracts caffeine-induced hyperactivity: evidence of dopaminergic blockade.
Topics: Animals; Caffeine; Catechin; Central Nervous System Stimulants; Hyperkinesis; Male; Mice; Mice, Inbred ICR; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior; Tea | 2010 |
Dual beneficial effects of (-)-epigallocatechin-3-gallate on levodopa methylation and hippocampal neurodegeneration: in vitro and in vivo studies.
Topics: Animals; Biological Products; Catechin; Catechol O-Methyltransferase Inhibitors; Cell Death; Cell Line; Enzyme Inhibitors; Hippocampus; Humans; Kainic Acid; Levodopa; Male; Methylation; Mice; Neurons; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2010 |
[Protective activity of different concentration of tea polyphenols and its major compound EGCG against whole body irradiation-induced injury in mice].
Topics: Animals; Camellia sinensis; Catechin; Disease Models, Animal; Female; Flavonoids; Humans; Male; Mice; Phenols; Plant Extracts; Polyphenols; Radiation Injuries; Radiation-Protective Agents; Random Allocation; Superoxide Dismutase; Whole-Body Irradiation | 2010 |
The flavanol (-)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP-induced toxicity.
Topics: alpha-Synuclein; Amyloid; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Catechin; Cell Culture Techniques; Diabetes Mellitus, Type 2; Flavonoids; Islet Amyloid Polypeptide; Microscopy, Electron, Transmission; Phenols; Polyphenols; Protease Nexins; Rats; Receptors, Cell Surface; Thiazoles | 2010 |
Hydrogen peroxide mediates EGCG-induced antioxidant protection in human keratinocytes.
Topics: Antioxidants; Apoptosis; Catalase; Catechin; Cell Line; Cytoprotection; DNA Damage; Humans; Hydrogen Peroxide; Keratinocytes; Oxidation-Reduction; Oxidative Stress | 2010 |
Effects of antioxidants on boar spermatozoa during sorting and storage.
Topics: Acrosome; Animals; Antioxidants; Catechin; Cell Survival; Male; Semen; Semen Analysis; Semen Preservation; Spermatozoa; Superoxide Dismutase; Swine | 2010 |
Role of (-)-epigallocatechin-3-gallate in cell viability, lipogenesis, and retinol-binding protein 4 expression in adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Blotting, Western; Catechin; Cell Culture Techniques; Cell Survival; Dose-Response Relationship, Drug; Flow Cytometry; Glucose; Humans; Lipid Metabolism; Mice; PPAR gamma; Reactive Oxygen Species; Retinol-Binding Proteins, Plasma | 2010 |
Solid-phase synthesis of a combinatorial methylated (±)-epigallocatechin gallate library and the growth-inhibitory effects of these compounds on melanoma B16 cells.
Topics: Animals; Antineoplastic Agents; Catechin; Cell Line, Tumor; Combinatorial Chemistry Techniques; Hydrogenation; Melanoma, Experimental; Methylation; Mice; Small Molecule Libraries | 2010 |
Thermodynamic analysis of the molecular interactions between amyloid beta-peptide 42 and (-)-epigallocatechin-3-gallate.
Topics: Amyloid beta-Peptides; Calorimetry; Catechin; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Osmolar Concentration; Peptide Fragments; Protein Binding; Temperature; Thermodynamics | 2010 |
Anticancer and anti-inflammatory effects of cysteine metabolites of the green tea polyphenol, (-)-epigallocatechin-3-gallate.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Catechin; Cell Line, Transformed; Cell Line, Tumor; Cell Proliferation; Cysteine; Humans; Mice; Rats; Tea | 2010 |
Regulation of Nrf2- and AP-1-mediated gene expression by epigallocatechin-3-gallate and sulforaphane in prostate of Nrf2-knockout or C57BL/6J mice and PC-3 AP-1 human prostate cancer cells.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Binding Sites; Catechin; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Isothiocyanates; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Promoter Regions, Genetic; Prostatic Neoplasms; Sulfoxides; Thiocyanates; Transcription Factor AP-1 | 2010 |
Gold nanoparticle mediated detection of prostate cancer cells using photoacoustic flowmetry with optical reflectance.
Topics: Acoustics; Catechin; Flow Cytometry; Gold; Humans; Male; Metal Nanoparticles; Neoplastic Cells, Circulating; Prostatic Neoplasms; Signal Processing, Computer-Assisted | 2010 |
Epigallocatechin-3 gallate, a green tea catechin, attenuated the downregulation of the cardiac gap junction induced by high glucose in neonatal rat cardiomyocytes.
Topics: Animals; Animals, Newborn; Catechin; Cells, Cultured; Connexin 43; Connexins; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Gap Junction alpha-5 Protein; Gap Junctions; Glucose; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Tea; Ventricular Remodeling | 2010 |
Amyloid formation and disaggregation of α-synuclein and its tandem repeat (α-TR).
Topics: alpha-Synuclein; Amyloid; Benzothiazoles; Catechin; Flavanones; Humans; Imidazoles; Imides; Ionic Liquids; Microscopy, Electron, Transmission; Parkinson Disease; Sulfonamides; Tandem Repeat Sequences; Thiazoles | 2010 |
Mobile phone radiation-induced free radical damage in the liver is inhibited by the antioxidants N-acetyl cysteine and epigallocatechin-gallate.
Topics: Acetylcysteine; Animals; Antioxidants; Catechin; Cell Phone; Electromagnetic Fields; Free Radicals; Glutathione Peroxidase; Guinea Pigs; Liver; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Peroxidase; Superoxide Dismutase; Time Factors | 2010 |
Plant aging and excess light enhance flavan-3-ol content in Cistus clusii.
Topics: Catechin; Cellular Senescence; Cistus; Flavonoids; Light; Lipid Peroxidation; Proanthocyanidins | 2011 |
Enhanced anti-tumor activity by the combination of the natural compounds (-)-epigallocatechin-3-gallate and luteolin: potential role of p53.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Caspase 3; Catechin; Cell Cycle Proteins; Cell Line, Tumor; DNA Damage; DNA-Binding Proteins; Drug Synergism; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Ki-67 Antigen; Luteolin; Mice; Mice, Nude; Mitochondria; Neoplasm Transplantation; Phosphorylation; Protein Serine-Threonine Kinases; Protein Stability; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2010 |
Geographical and climatic dependencies of green tea (Camellia sinensis) metabolites: a (1)H NMR-based metabolomics study.
Topics: Amino Acids; Caffeine; Camellia sinensis; Catechin; Climate; Discriminant Analysis; Glutamates; Magnetic Resonance Spectroscopy; Metabolomics; Multivariate Analysis; Republic of Korea | 2010 |
Comparison of the effect of oligonol, a new lychee fruit-derived low molecular form of polyphenol, and epigallocatechin-3-gallate on lipolysis in rat primary adipocytes.
Topics: Adipocytes; Animals; Catechin; Cells, Cultured; Fruit; Heme Oxygenase-1; Lipolysis; Litchi; Male; Mitogen-Activated Protein Kinases; Phenols; Rats; Rats, Wistar | 2011 |
The evaluation of catechins that contain a galloyl moiety as potential HIV-1 integrase inhibitors.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Catechin; DNA, Viral; Enzyme-Linked Immunosorbent Assay; HIV Integrase; HIV Integrase Inhibitors; HIV-1; Humans; Pyrrolidinones; Raltegravir Potassium | 2010 |
Lovastatin interacts with natural products to influence cultured hepatocarcinoma cell (hep-g2) growth.
Topics: Antineoplastic Agents; Capsaicin; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cells, Cultured; Curcumin; Drug Synergism; Hep G2 Cells; Herb-Drug Interactions; Humans; Liver Neoplasms; Lovastatin; Plant Extracts | 2010 |
Oxidative stress-mediated bimodal regulation of polymorphonuclear leukocyte spreading by polyphenolic compounds.
Topics: Animals; Antioxidants; Catechin; Glycine; Hydrogen Peroxide; Hydroquinones; Neutrophils; Oxidative Stress; Pyrogallol; Sulfhydryl Compounds; Superoxides; Swine; Tannins | 2010 |
Encapsulation of epigallocatechin-3-gallate (EGCG) using oil-in-water (O/W) submicrometer emulsions stabilized by ι-carrageenan and β-lactoglobulin.
Topics: Antineoplastic Agents; Capsules; Carrageenan; Catechin; Drug Stability; Emulsions; Hep G2 Cells; Humans; Lactoglobulins; Pressure | 2010 |
EGCG functions through estrogen receptor-mediated activation of ADAM10 in the promotion of non-amyloidogenic processing of APP.
Topics: ADAM Proteins; ADAM10 Protein; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Catechin; Cell Line; Disease Models, Animal; Estrogen Receptor alpha; Female; Furin; Humans; Membrane Proteins; Mice; Models, Biological; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Signal Transduction | 2010 |
Novel chemotherapeutic and renal protective effects for the green tea (EGCG): role of oxidative stress and inflammatory-cytokine signaling.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Antioxidants; C-Reactive Protein; Camellia sinensis; Carcinoma, Ehrlich Tumor; Catechin; Cisplatin; Cytokines; Female; Glomerular Filtration Rate; Kidney; Male; Malondialdehyde; Mice; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Renal Agents; Signal Transduction | 2010 |
Epigallocatechin-3-gallate prevents lipid peroxidation and enhances antioxidant defense system via modulating hepatic nuclear transcription factors in heat-stressed quails.
Topics: Animals; Antioxidants; Biomarkers; Catechin; Coturnix; Female; Gene Expression Regulation; Hot Temperature; Lipid Peroxidation; Liver; Oxidative Stress; Quail; Transcription Factors | 2010 |
Tea catechin EGCg suppresses the mgl gene associated with halitosis.
Topics: Anti-Infective Agents; Bacterial Proteins; Blotting, Western; Carbon-Sulfur Lyases; Catechin; Enzyme Inhibitors; Halitosis; Humans; Microbial Sensitivity Tests; Porphyromonas gingivalis; RNA, Bacterial; Spectrophotometry; Sulfhydryl Compounds; Sulfur Compounds; Time Factors; Volatile Organic Compounds | 2010 |
Supplementation of green tea catechins in dentifrices suppresses gingival oxidative stress and periodontal inflammation.
Topics: Alveolar Bone Loss; Animals; Antioxidants; Camellia sinensis; Catechin; Connective Tissue; Dentifrices; Disease Models, Animal; Epithelial Attachment; Gingiva; Gingival Recession; Lipid Peroxidation; Lysine; Male; NF-kappa B; Oxidative Stress; Periodontitis; Random Allocation; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Tyrosine | 2011 |
Green tea catechin, epigallocatechin gallate, suppresses signaling by the dsRNA innate immune receptor RIG-I.
Topics: Antioxidants; Camellia sinensis; Catechin; DEAD Box Protein 58; DEAD-box RNA Helicases; Down-Regulation; HEK293 Cells; Humans; Immunity, Innate; Plant Extracts; Receptors, Immunologic; RNA, Double-Stranded; Signal Transduction | 2010 |
Proinflammatory effect of cholesterol and its oxidation products on CaCo-2 human enterocyte-like cells: effective protection by epigallocatechin-3-gallate.
Topics: Antioxidants; Apoptosis; Caco-2 Cells; Catechin; Cholesterol; Enterocytes; Enzyme Activation; Humans; Hydroxycholesterols; Inflammation Mediators; Interleukin-8; Ketocholesterols; NADPH Oxidases; Onium Compounds; Up-Regulation | 2010 |
Metabolism of green tea catechins by the human small intestine.
Topics: Catechin; Chromatography, High Pressure Liquid; Gallic Acid; Humans; In Vitro Techniques; Intestine, Small; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tea | 2010 |
Laser modulated transmembrane convection: Implementation in cancer chemotherapy.
Topics: Antineoplastic Agents; Biological Transport; Catechin; Cell Count; Cell Membrane; Cell Membrane Permeability; Diffusion; Doxorubicin; Drug Resistance, Neoplasm; Female; HeLa Cells; Humans; Lasers; Methotrexate; Models, Biological; Time Factors; Uterine Cervical Neoplasms; Viscosity | 2010 |
Green tea polyphenols potentiate the action of nerve growth factor to induce neuritogenesis: possible role of reactive oxygen species.
Topics: Animals; Antioxidants; Catechin; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Nerve Growth Factor; Neurites; PC12 Cells; Phenols; Polyphenols; Rats; Tea | 2010 |
Catechin inhibits adhesion and migration of peripheral blood B cells by blocking CD11b.
Topics: B-Lymphocyte Subsets; Catechin; CD11b Antigen; Cell Adhesion; Cell Movement; Cells, Cultured; Endothelial Cells; Humans; Tea | 2011 |
Synergistic epigenetic reactivation of estrogen receptor-α (ERα) by combined green tea polyphenol and histone deacetylase inhibitor in ERα-negative breast cancer cells.
Topics: Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Survival; Chromatin Immunoprecipitation; DNA Methylation; Drug Synergism; Estrogen Receptor alpha; Female; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Polymerase Chain Reaction; Promoter Regions, Genetic; Tamoxifen | 2010 |
Cytotoxicity of arsenic trioxide is enhanced by (-)-epigallocatechin-3-gallate via suppression of ferritin in cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Caffeic Acids; Catechin; Cell Line, Tumor; Cytotoxins; Drug Synergism; Ferritins; Heme Oxygenase (Decyclizing); HL-60 Cells; Humans; Neoplasms; Oxides; Phenylethyl Alcohol | 2011 |
Molecular bases of thioredoxin and thioredoxin reductase-mediated prooxidant actions of (-)-epigallocatechin-3-gallate.
Topics: Amino Acid Sequence; Animals; Catalytic Domain; Catechin; Cattle; Cysteine; HeLa Cells; Humans; Oxidation-Reduction; Protein Binding; Rats; Reactive Oxygen Species; Recombinant Proteins; Thioredoxin-Disulfide Reductase; Thioredoxins | 2010 |
Inhibitory effect of epigallocatechin gallate (EGCG), resveratrol, and curcumin on proliferation of human retinal pigment epithelial cells in vitro.
Topics: Antioxidants; Apoptosis; Caspases; Catechin; Cell Division; Cell Proliferation; Cell Survival; Cells, Cultured; Curcumin; Flow Cytometry; Humans; Necrosis; Resveratrol; Retinal Pigment Epithelium; Stilbenes | 2010 |
Apoptosis of human fibrosarcoma HT-1080 cells by epigallocatechin-3-O-gallate via induction of p53 and caspases as well as suppression of Bcl-2 and phosphorylated nuclear factor-κB.
Topics: Active Transport, Cell Nucleus; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Caspases; Catechin; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Nucleus; Fibrosarcoma; Gene Expression; Humans; NF-kappa B; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tumor Suppressor Protein p53 | 2011 |
(-)-Epigallocatechin 3-gallate (EGCG) at the ocular surface inhibits corneal neovascularization.
Topics: Animals; Catechin; Corneal Neovascularization; Eye; Humans; Interleukin-1beta; NF-kappa B; Transcription Factor RelA; Vision, Ocular | 2011 |
Combination therapy with epigallocatechin-3-gallate and doxorubicin in human prostate tumor modeling studies: inhibition of metastatic tumor growth in severe combined immunodeficiency mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Catechin; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Humans; Male; Mice; Mice, Inbred C57BL; Mice, SCID; Neoplasm Metastasis; Prostatic Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays | 2010 |
Novel anti-fatty acid synthase compounds with anti-cancer activity in HER2+ breast cancer.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Breast Neoplasms; Catechin; Cell Survival; Fatty Acid Synthases; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Prognosis; Receptor, ErbB-2 | 2010 |
Exploring the chemical sensitivity of a carbon nanotube/green tea composite.
Topics: Catechin; Electrodes; Hydrogen Peroxide; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Nanocomposites; Nanotubes, Carbon; Oxidation-Reduction; Spectrum Analysis; Tea; Transistors, Electronic | 2010 |
Comparative effects of dietary flavanols on antioxidant defences and their response to oxidant-induced stress on Caco2 cells.
Topics: Antioxidants; Biflavonoids; Caco-2 Cells; Caspase 3; Catechin; Cell Survival; Diet; Glutathione; Glutathione Peroxidase; Humans; Oxidative Stress; Proanthocyanidins; Reactive Oxygen Species | 2011 |
Potential mechanisms behind (-)-epigallocatechin-3-gallate protection against cerebral ischemic injury.
Topics: Animals; Brain Ischemia; Catechin; Humans; Neuroprotective Agents; Reperfusion Injury | 2011 |
Extraction and isolation of catechins from tea.
Topics: Animals; Antioxidants; Caffeine; Catechin; Chromatography, Supercritical Fluid; Humans; Molecular Structure; Plant Extracts; Solid Phase Extraction; Solvents; Tea | 2010 |
Catechin derivatives from Parapiptadenia rigida with in vitro wound-healing properties.
Topics: Animals; Brazil; Catechin; DNA; Fabaceae; Mice; Mitogen-Activated Protein Kinase 14; Molecular Structure; NF-kappa B; Nuclear Magnetic Resonance, Biomolecular; Plant Bark; Swiss 3T3 Cells; Wound Healing | 2010 |
Selective inhibitory effect of epigallocatechin-3-gallate on migration of vascular smooth muscle cells.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Catechin; Cell Movement; Cell Proliferation; Cells, Cultured; Endothelial Cells; Immunohistochemistry; Male; Myocytes, Smooth Muscle; Rats; Rats, Sprague-Dawley | 2010 |
Formulation of a medical food cocktail for Alzheimer's disease: beneficial effects on cognition and neuropathology in a mouse model of the disease.
Topics: Acetylcysteine; Alkaloids; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Ascorbic Acid; Benzodioxoles; Brain; Catechin; Cerebral Cortex; Cognition; Curcumin; Dietary Supplements; Folic Acid; Hippocampus; Humans; Immunoblotting; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Transgenic; Piperidines; Polyunsaturated Alkamides; Thioctic Acid; Vitamin B Complex; Vitamins | 2010 |
Down-regulation of connexin43 gap junction by serum deprivation in human endothelial cells was improved by (-)-Epigallocatechin gallate via ERK MAP kinase pathway.
Topics: Catechin; Cells, Cultured; Chromones; Connexin 43; Culture Media, Serum-Free; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gap Junctions; Humans; Imidazoles; Morpholines; NG-Nitroarginine Methyl Ester; Pyridines; RNA, Small Interfering; Signal Transduction | 2011 |
Intra-peritoneal application of catechins and EGCG as in vivo inhibitors of ozone-induced oxidative stress.
Topics: Animals; Antioxidants; Catechin; Copper; Female; Glutathione Peroxidase; Injections, Intraperitoneal; Lipid Peroxidation; Oxidative Stress; Ozone; Rats; Rats, Wistar; Superoxide Dismutase; Zinc | 2011 |
Cardioprotective effects of epigallocatechin-3-gallate against doxorubicin-induced cardiomyocyte injury.
Topics: Animals; Antioxidants; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Male; Myocytes, Cardiac; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2011 |
Concise synthesis of catechin probes enabling analysis and imaging of EGCg.
Topics: Amines; Antioxidants; Catechin; Endothelial Cells; Humans; Image Processing, Computer-Assisted; Microscopy, Fluorescence; Tea; Umbilical Veins | 2011 |
Biochemical characterization of epigallocatechin-3-gallate as an effective stimulator for the phosphorylation of its binding proteins by glycogen synthase kinase-3β in vitro.
Topics: Animals; Camellia sinensis; Carrier Proteins; Catechin; Cattle; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Intercellular Signaling Peptides and Proteins; Luteolin; Myelin Basic Protein; Nerve Tissue Proteins; Phosphorylation; Plant Extracts; Quercetin; Rats; tau Proteins; Vimentin | 2010 |
Epigallocatechin gallate delays the onset of type 1 diabetes in spontaneous non-obese diabetic mice.
Topics: Animals; Apoptosis; Caspase 3; Catechin; Cell Survival; Diabetes Mellitus, Type 1; Dietary Supplements; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Interleukin-10; Interleukin-12; Islets of Langerhans; Mice; Mice, Inbred NOD; Organ Culture Techniques; Random Allocation; Survival Analysis | 2011 |
Protective effects of epigallocatechin-3-gallate against lead-induced oxidative damage.
Topics: Animals; Antioxidants; Catalase; Catechin; In Vitro Techniques; Lead; Lipid Peroxidation; Malondialdehyde; Myocytes, Cardiac; Oxidative Stress; Rats; Reactive Oxygen Species; Superoxide Dismutase | 2011 |
The tea catechin epigallocatechin gallate suppresses cariogenic virulence factors of Streptococcus mutans.
Topics: Anti-Infective Agents; Bacterial Proteins; Biofilms; Catechin; Gene Expression; Glucosyltransferases; Polymerase Chain Reaction; Streptococcus mutans; Tea; Virulence Factors | 2011 |
Effect on the epigallocatechin gallate/epigallocatechin ratio in a green tea (Camellia sinensis L.) extract of different extraction temperatures and its effect on IgA production in mice.
Topics: Animals; Camellia sinensis; Catechin; Chemical Fractionation; Female; Immunoglobulin A; Immunologic Factors; Mice; Mice, Inbred BALB C; Peyer's Patches; Tea; Temperature | 2010 |
Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Benzamides; Captopril; Catechin; Cell Differentiation; Cell Line; Cell Proliferation; Dioxoles; Dose-Response Relationship, Drug; Mice; Muscle Development; Myoblasts; Receptors, Transforming Growth Factor beta; Resveratrol; Signal Transduction; Smad3 Protein; Stilbenes; Transforming Growth Factor beta1; Tretinoin; Vitamin D; Vitamins | 2010 |
Epigallocatechin-3-gallate (EGCG) downregulates EGF-induced MMP-9 in breast cancer cells: involvement of integrin receptor α5β1 in the process.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Catechin; Cell Adhesion; Cell Line, Tumor; Down-Regulation; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Female; Fibronectins; Focal Adhesion Kinase 1; Gene Silencing; Humans; Integrin alpha5beta1; Matrix Metalloproteinase 9; Neoplasm Proteins; Phosphorylation; Protein Processing, Post-Translational; RNA, Messenger; RNA, Small Interfering; Signal Transduction | 2011 |
Sulfur mustard induced oxidative stress and its alteration by epigallocatechin gallate.
Topics: Animals; Antioxidants; Catechin; Chemical Warfare Agents; Female; Lipid Peroxidation; Mustard Gas; Oxidative Stress; Rats; Rats, Wistar | 2011 |
Green tea polyphenol EGCG blunts androgen receptor function in prostate cancer.
Topics: Androgen Receptor Antagonists; Binding, Competitive; Catechin; Computer Simulation; Fluorescence Resonance Energy Transfer; Humans; Male; MicroRNAs; Prostatic Neoplasms; Receptors, Androgen; Tea; Transcriptional Activation; Tumor Cells, Cultured | 2011 |
Epigallocatechin gallate-loaded polysaccharide nanoparticles for prostate cancer chemoprevention.
Topics: Anticarcinogenic Agents; Apoptosis; Carcinoma; Caspase 3; Catechin; Cell Line; Cell Survival; Chemoprevention; Gum Arabic; Humans; Male; Nanoparticles; Polysaccharides; Prostatic Neoplasms; Tea | 2011 |
The anticancer flavonoid chrysin induces the unfolded protein response in hepatoma cells.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Caspase 7; Catechin; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Eukaryotic Initiation Factor-2; Flavonoids; Heat-Shock Proteins; Hep G2 Cells; Humans; Liver Neoplasms; Phosphorylation; Poly(ADP-ribose) Polymerases; Proteasome Inhibitors; Regulatory Factor X Transcription Factors; RNA Interference; Transcription Factors; Unfolded Protein Response | 2011 |
In vitro studies on the inhibition of colon cancer by butyrate and polyphenolic compounds.
Topics: Analysis of Variance; Anticarcinogenic Agents; Apoptosis; Butyrates; Caco-2 Cells; Catechin; Cell Differentiation; Cell Proliferation; Cell Survival; Flavonoids; Humans; Phenols; Polyphenols; Propiophenones; Quercetin; Regression Analysis; Resveratrol; Rutin; Stilbenes | 2011 |
(-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells.
Topics: Acetylation; Anticarcinogenic Agents; Azacitidine; Catechin; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Genes, p16; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Skin Neoplasms; Transcriptional Activation | 2011 |
Epigallocatechin-3-gallate inhibits paracrine and autocrine hepatocyte growth factor/scatter factor-induced tumor cell migration and invasion.
Topics: Animals; Autocrine Communication; Catechin; Cell Line, Tumor; Cell Movement; Female; Hepatocyte Growth Factor; Humans; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Paracrine Communication; Phosphorylation; Proto-Oncogene Proteins c-met; Receptors, Growth Factor; Signal Transduction | 2011 |
Green tea polyphenol epigallocatechin-3-gallate (EGCG) induced intermolecular cross-linking of membrane proteins.
Topics: Ascorbic Acid; Benzoquinones; Catechin; Cell Membrane; Cross-Linking Reagents; Edetic Acid; Erythrocytes; Flavonoids; Humans; Membrane Proteins; Molecular Weight; Phenols; Polyphenols; Protein Multimerization; Protein Structure, Quaternary; Reactive Oxygen Species; Sulfhydryl Compounds; Tea | 2011 |
Human serum albumin as an antioxidant in the oxidation of (-)-epigallocatechin gallate: participation of reversible covalent binding for interaction and stabilization.
Topics: Aerobiosis; Amination; Antioxidants; Catechin; Humans; Oxidation-Reduction; Protein Binding; Pyrogallol; Serum Albumin; Water | 2011 |
Influence of the galloyl moiety in tea catechins on binding affinity for human serum albumin.
Topics: Antioxidants; Catechin; Humans; Kinetics; Protein Binding; Serum Albumin; Tea | 2010 |
Epicatechin gallate and catechin gallate are superior to epigallocatechin gallate in growth suppression and anti-inflammatory activities in pancreatic tumor cells.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Blotting, Western; Carcinoma, Pancreatic Ductal; Catechin; Cell Cycle; Cell Proliferation; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Fluorescent Antibody Technique; Humans; Pancreatic Neoplasms; Tea; Tumor Cells, Cultured | 2011 |
[Toxic hepatitis triggered by green tea].
Topics: Animals; Antioxidants; Camellia sinensis; Catechin; Chemical and Drug Induced Liver Injury; Humans; Liver; Tea | 2011 |
Green tea epigallocatechin gallate enhances therapeutic efficacy of temozolomide in orthotopic mouse glioblastoma models.
Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Camellia sinensis; Catechin; Cell Line, Tumor; Dacarbazine; Disease Models, Animal; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Glioblastoma; Humans; Immunohistochemistry; Mice; Mice, Knockout; Temozolomide | 2011 |
Evaluation of the bitterness of green tea catechins by a cell-based assay with the human bitter taste receptor hTAS2R39.
Topics: Catechin; HEK293 Cells; Humans; Receptors, Cell Surface; Taste; Tea | 2011 |
(-)-Epigallocatechin-3-gallate suppresses growth of AZ521 human gastric cancer cells by targeting the DEAD-box RNA helicase p68.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Proliferation; DEAD-box RNA Helicases; Drug Screening Assays, Antitumor; Humans; Molecular Conformation; Stereoisomerism; Stomach Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured | 2011 |
Interactions of green tea catechins with organic anion-transporting polypeptides.
Topics: Aniline Compounds; Animals; Antioxidants; Biological Transport; Camellia sinensis; Catechin; Cell Line; CHO Cells; Cricetinae; Cricetulus; Drug Interactions; Enterocytes; Estradiol; Estrone; Fluorescent Dyes; Hepatocytes; Humans; Organic Anion Transporters; Tea; Xanthenes | 2011 |
Light- and sodium azide-induced death of RGC-5 cells in culture occurs via different mechanisms.
Topics: Amino Acid Chloromethyl Ketones; Blotting, Western; Caspase 3; Catechin; Cell Culture Techniques; Cell Death; Cell Line; Cell Nucleus; Cell Survival; DNA; Imidazoles; Immunohistochemistry; Indoles; Light; Phosphatidylserines; Reactive Oxygen Species; Retinal Ganglion Cells; Sodium Azide; Staurosporine | 2011 |
Artefacts in cell culture: α-Ketoglutarate can scavenge hydrogen peroxide generated by ascorbate and epigallocatechin gallate in cell culture media.
Topics: Animals; Artifacts; Ascorbic Acid; Catechin; Cell Culture Techniques; Cells, Cultured; Culture Media; Hydrogen Peroxide; Ketoglutaric Acids; Oxidation-Reduction; Succinic Acid | 2011 |
Epigallocatechin-3-gallate protects kidneys from ischemia reperfusion injury by HO-1 upregulation and inhibition of macrophage infiltration.
Topics: Actins; Animals; Apoptosis; Benzothiazoles; Catechin; Diamines; Heme Oxygenase (Decyclizing); Kidney; Lipid Peroxidation; Macrophages; Malondialdehyde; Muscle, Smooth; Organic Chemicals; Quinolines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation | 2011 |
Green tea (-)-epigallocatechin-3-gallate inhibits HGF-induced progression in oral cavity cancer through suppression of HGF/c-Met.
Topics: Animals; Catechin; Cell Movement; Cell Proliferation; Chemoprevention; Disease Progression; Female; Hepatocyte Growth Factor; Humans; KB Cells; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mouth Neoplasms; Neoplasm Invasiveness; Proto-Oncogene Proteins c-met; Signal Transduction; Tea | 2011 |
Epigallocatechin gallate (EGCG), a major component of green tea, is a dual phosphoinositide-3-kinase/mTOR inhibitor.
Topics: Antineoplastic Agents; Catechin; Cell Proliferation; HEK293 Cells; Humans; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Tea; TOR Serine-Threonine Kinases | 2011 |
Effects of antioxidants on drug absorption in in vivo intestinal ischemia/reperfusion.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Antioxidants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Catechin; Dextrans; Fluorescein-5-isothiocyanate; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Rats; Rats, Wistar; Reperfusion Injury; Xanthophylls | 2011 |
Targeted biocompatible nanoparticles for the delivery of (-)-epigallocatechin 3-gallate to prostate cancer cells.
Topics: Anticarcinogenic Agents; Catalytic Domain; Catechin; Cell Line, Tumor; Cell Proliferation; Dipeptides; Drug Carriers; Humans; Kinetics; Male; Molecular Targeted Therapy; Nanoparticles; Polyesters; Prostate-Specific Antigen; Prostatic Neoplasms | 2011 |
Epigallocatechin-3-gallate reduces airway inflammation in mice through binding to proinflammatory chemokines and inhibiting inflammatory cell recruitment.
Topics: Animals; Binding Sites; Catechin; Cell Migration Inhibition; Cells, Cultured; Chemokine CXCL10; Chemokine CXCL11; Chemokine CXCL9; Chemokines; Disease Models, Animal; Inflammation Mediators; Lung; Male; Mice; Mice, Inbred BALB C; Mice, SCID; Mice, Transgenic | 2011 |
Epigallocatechin gallate elicits contractions of the isolated aorta of the aged spontaneously hypertensive rat.
Topics: Acetylcholine; Adenosine Triphosphate; Aging; Animals; Antioxidants; Aorta, Thoracic; Catechin; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypertension; Male; Microscopy, Confocal; Muscle Contraction; Oxidative Stress; Prostaglandins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Tea | 2011 |
Green tea epigallocatechin gallate exhibits anticancer effect in human pancreatic carcinoma cells via the inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Activation; Focal Adhesion Kinase 1; Humans; Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Receptor, IGF Type 1; Tea | 2010 |
Characterization of unusual proanthocyanidins in leaves of bayberry ( Myrica rubra Sieb. et Zucc.).
Topics: Catechin; Chromatography, High Pressure Liquid; Myrica; Phenols; Phloroglucinol; Plant Leaves; Proanthocyanidins | 2011 |
Green tea polyphenol epigallocatechin-3-gallate inhibits TLR2 signaling induced by peptidoglycan through the polyphenol sensing molecule 67-kDa laminin receptor.
Topics: Animals; Catechin; Down-Regulation; Enzyme Activation; Flavonoids; Inflammation Mediators; Intracellular Signaling Peptides and Proteins; Macrophages, Peritoneal; MAP Kinase Signaling System; Mice; Molecular Weight; Peptidoglycan; Phenols; Polyphenols; Receptors, Laminin; Signal Transduction; Tea; Toll-Like Receptor 2 | 2011 |
Epigallocatechin-3-gallate induces cell apoptosis of human chondrosarcoma cells through apoptosis signal-regulating kinase 1 pathway.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Catechin; Cell Line, Tumor; Chondrosarcoma; Flow Cytometry; Humans; Male; MAP Kinase Kinase Kinase 5; Membrane Potential, Mitochondrial; Mice; Mice, SCID; Reactive Oxygen Species; Rhodamines; RNA, Small Interfering; Signal Transduction; Xenograft Model Antitumor Assays | 2011 |
GRP78/BiP modulation of GRP78/BiP in altering sensitivity to chemotherapy.
Topics: Activating Transcription Factor 6; Animals; Antineoplastic Agents; Brain Neoplasms; Catechin; Cell Line, Tumor; Cells, Cultured; Cytological Techniques; Dacarbazine; Endoplasmic Reticulum Chaperone BiP; Gene Expression Regulation, Neoplastic; Glioma; Heat-Shock Proteins; Humans; Immunohistochemistry; Mice; Rats; Temozolomide | 2011 |
Targeting the unfolded protein response in cancer therapy.
Topics: Animals; Antineoplastic Agents; Catechin; Cell Line; Drug Screening Assays, Antitumor; Endoplasmic Reticulum Chaperone BiP; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Heat-Shock Proteins; Humans; Neoplasms; Thapsigargin; Unfolded Protein Response | 2011 |
Interaction of green tea polyphenol epigallocatechin-3-gallate with sunitinib: potential risk of diminished sunitinib bioavailability.
Topics: Animals; Biological Availability; Catechin; Chemical Precipitation; Herb-Drug Interactions; Humans; Indoles; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Plant Extracts; Pyrroles; Rats; Rats, Sprague-Dawley; Sunitinib; Tea | 2011 |
Extraction of antioxidants and caffeine from green tea (Camelia sinensis) leaves: kinetics and modeling.
Topics: Antioxidants; Caffeine; Camellia sinensis; Catechin; Diffusion; Food Handling; Hot Temperature; Iran; Isomerism; Kinetics; Models, Chemical; Plant Leaves; Solubility; Tea | 2010 |
Modulation of Ca²⁺ signals by epigallocatechin-3-gallate(EGCG) in cultured rat hippocampal neurons.
Topics: Animals; Calcium Signaling; Catechin; Cells, Cultured; Female; Hippocampus; Male; Neurons; Rats; Rats, Sprague-Dawley; Type C Phospholipases | 2011 |
(-)-Epigallocatechin-3-gallate induces apoptosis in gastric cancer cell lines by down-regulating survivin expression.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Line, Tumor; DNA-Binding Proteins; Down-Regulation; Humans; Inhibitor of Apoptosis Proteins; Nuclear Proteins; Stomach Neoplasms; Survivin; Tumor Protein p73; Tumor Suppressor Proteins | 2011 |
Epigallocatechin-3-gallate inhibits lactase but is alleviated by salivary proline-rich proteins.
Topics: Animals; Catechin; Cattle; Digestion; Down-Regulation; Enzyme Inhibitors; Humans; Intestine, Small; Kinetics; Lactase; Lactose; Models, Biological; Plant Extracts; Rats; Salivary Proline-Rich Proteins; Tea | 2011 |
Protective effect of quercetin, EGCG, catechin and betaine against oxidative stress induced by ethanol in vitro.
Topics: Aldehydes; Anti-Infective Agents, Local; Antioxidants; Betaine; Blotting, Western; Carcinoma, Hepatocellular; Catechin; Cells, Cultured; Cytochrome P-450 CYP2E1; Ethanol; Gastrointestinal Agents; Hepatocytes; Humans; In Vitro Techniques; Liver Neoplasms; Malondialdehyde; Oxidative Stress; Quercetin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2011 |
Identification of an EGCG oxidation derivative with proteasome modulatory activity.
Topics: Antioxidants; Catechin; Cell Survival; Computer Simulation; Drug Stability; HeLa Cells; Humans; Models, Molecular; Molecular Structure; Oxidation-Reduction; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Protein Carbonylation; Proteins; Surface Properties; Ubiquitination | 2011 |
Epigallocatechin-3-gallate potently inhibits the in vitro activity of hydroxy-3-methyl-glutaryl-CoA reductase.
Topics: Biosensing Techniques; Catechin; Computational Biology; Enzyme Activation; Enzyme Assays; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Microsomes, Liver; Recombinant Proteins | 2011 |
Anti-inflammatory and anti-oxidative effects of the green tea polyphenol epigallocatechin gallate in human corneal epithelial cells.
Topics: Anti-Inflammatory Agents; Antioxidants; Catechin; Cytokines; Enzyme Activation; Epithelial Cells; Epithelium, Corneal; Flavonoids; Glucose Oxidase; Humans; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; NF-kappa B; Osmotic Pressure; p38 Mitogen-Activated Protein Kinases; Phenols; Phosphorylation; Polyphenols; Reactive Oxygen Species; Tea; Transcription Factor AP-1; Transcriptional Activation | 2011 |
Tea polyphenol (-)-epigallocatechin-3-gallate inhibits nicotine- and estrogen-induced α9-nicotinic acetylcholine receptor upregulation in human breast cancer cells.
Topics: Antineoplastic Agents, Hormonal; Catechin; Cell Line, Tumor; Cell Proliferation; Estrogens; Female; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Nicotine; Nicotinic Antagonists; Phenols; Polyphenols; Receptors, Nicotinic; RNA, Messenger; Signal Transduction; Tea; Up-Regulation | 2011 |
EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages.
Topics: Animals; Autophagy; Blotting, Western; Catechin; Cell Line; Cytoplasm; HMGB1 Protein; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred BALB C; Microscopy, Electron, Transmission; Rats; RNA Interference | 2011 |
Preventive effects of (-)-epigallocatechin gallate on diethylnitrosamine-induced liver tumorigenesis in obese and diabetic C57BL/KsJ-db/db Mice.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Carcinogens; Catechin; Diabetes Mellitus, Experimental; Diethylnitrosamine; Extracellular Signal-Regulated MAP Kinases; Fatty Acids, Nonesterified; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Obesity; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1 | 2011 |
Anti-angiogenic activity and intracellular distribution of epigallocatechin-3-gallate analogs.
Topics: Actins; Angiogenesis Inhibitors; Biological Transport; Camellia sinensis; Catechin; Cell Line; Cell Movement; Cell Proliferation; Cytoplasm; Endothelial Cells; Endothelium, Vascular; Humans; Mitochondria; Neovascularization, Pathologic; Plant Extracts | 2011 |
Green tea may be benefit to the therapy of atrial fibrillation.
Topics: Animals; Antioxidants; Atrial Fibrillation; Catechin; Fibrosis; Humans; Inflammation; Myocardium; Oxidative Stress; Phytotherapy; Plant Extracts; Tea | 2011 |
Green tea constituents (-)-epigallocatechin-3-gallate (EGCG) and gallic acid induce topoisomerase I- and topoisomerase II-DNA complexes in cells mediated by pyrogallol-induced hydrogen peroxide.
Topics: Animals; Biocatalysis; Catalase; Catechin; Cell Death; Cell Line; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Flavonoids; Gallic Acid; Humans; Hydrogen Peroxide; Mice; Models, Biological; Pyrogallol; Tea; Time Factors | 2011 |
Epigallocatechin-3 gallate inhibits invasion, epithelial-mesenchymal transition, and tumor growth in oral cancer cells.
Topics: Base Sequence; Carcinoma, Squamous Cell; Catechin; Cell Division; Cell Line, Tumor; DNA Primers; Epithelial-Mesenchymal Transition; Fluorescent Antibody Technique; Humans; Mouth Neoplasms; Neoplasm Invasiveness; Reverse Transcriptase Polymerase Chain Reaction | 2011 |
Antioxidative activity of microbial metabolites of (-)-epigallocatechin gallate produced in rat intestines.
Topics: Animals; Antioxidants; Benzothiazoles; Catechin; Flow Injection Analysis; Free Radical Scavengers; Intestinal Mucosa; Intestines; Lactones; Microbiological Phenomena; Rats; Sulfonic Acids; Tea | 2011 |
The effect of green tea extract and EGCG on the signaling network in squamous cell carcinoma.
Topics: Anticarcinogenic Agents; Antioxidants; Carcinoma, Squamous Cell; Catechin; Cell Cycle; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Phosphorylation; Plant Extracts; Signal Transduction; Tea | 2011 |
Epigallocatechin-3-gallate effectively attenuates skeletal muscle atrophy caused by cancer cachexia.
Topics: Animals; Anticarcinogenic Agents; Blotting, Western; Cachexia; Carcinoma, Lewis Lung; Catechin; Fluorescent Antibody Technique; Male; Mice; Mice, Inbred C57BL; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; NF-kappa B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; SKP Cullin F-Box Protein Ligases; Tripartite Motif Proteins; Ubiquitin-Protein Ligases | 2011 |
Preclinical evaluation of the antitumor activity of bortezomib in combination with vitamin C or with epigallocatechin gallate, a component of green tea.
Topics: Animals; Antineoplastic Agents; Ascorbic Acid; Boronic Acids; Bortezomib; Catechin; Chromatography, Liquid; Drug Screening Assays, Antitumor; Female; Humans; Male; Mice; Mice, SCID; Prostatic Neoplasms; Pyrazines; Tandem Mass Spectrometry; Tea; Xenograft Model Antitumor Assays | 2011 |
Capillary electrophoresis methods for the determination of covalent polyphenol-protein complexes.
Topics: Animals; Catechin; Cattle; Electrophoresis, Capillary; Food Analysis; Polyphenols; Sensitivity and Specificity; Serum Albumin, Bovine; Wine | 2011 |
Procyanidin dimer B1 and trimer C1 impair inflammatory response signalling in human monocytes.
Topics: Antioxidants; Biflavonoids; Catechin; Cell Line; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Free Radicals; Humans; I-kappa B Kinase; Inflammation; Lipopolysaccharides; MAP Kinase Signaling System; Monocytes; NF-kappa B; Phosphorylation; Proanthocyanidins; Reactive Oxygen Species; Signal Transduction | 2011 |
A novel prodrug of epigallocatechin-3-gallate: differential epigenetic hTERT repression in human breast cancer cells.
Topics: Anticarcinogenic Agents; Apoptosis; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; DNA Modification Methylases; Epigenesis, Genetic; Female; Flow Cytometry; Histone Acetyltransferases; Humans; Prodrugs; Promoter Regions, Genetic; Telomerase | 2011 |
Characterization, antimicrobial activity, and mechanism of a high-performance (-)-epigallocatechin-3-gallate (EGCG)-CuII/polyvinyl alcohol (PVA) nanofibrous membrane.
Topics: Anti-Infective Agents; Bacteria; Catechin; Copper; Drug Delivery Systems; Drug Stability; Fungi; Membranes, Artificial; Microbial Viability; Nanostructures; Polyvinyl Alcohol | 2011 |
Proliferation of smooth muscle cells stimulated by Porphyromonas gingivalis is inhibited by apple polyphenol.
Topics: Adhesins, Bacterial; Aorta; Arterial Occlusive Diseases; Catechin; Cell Proliferation; Chlorogenic Acid; Culture Media, Conditioned; Cysteine Endopeptidases; Fimbriae, Bacterial; Flavonoids; Gingipain Cysteine Endopeptidases; Humans; Muscle, Smooth, Vascular; Mutation; Myocytes, Smooth Muscle; Plant Extracts; Porphyromonas gingivalis; Protease Inhibitors; Statistics, Nonparametric; Tannins; Tunica Intima | 2011 |
Development of (-)-epigallocatechin-3-gallate (EGCG)-loaded enteric microparticles with intestinal mucoadhesive property.
Topics: Adhesiveness; Animals; Antioxidants; Catechin; Delayed-Action Preparations; Drug Carriers; Drug Stability; Emulsions; Hydrogen-Ion Concentration; In Vitro Techniques; Intestine, Small; Microsomes; Microspheres; Particle Size; Polymethacrylic Acids; Polyvinyl Alcohol; Rats; Solvents | 2011 |
[Adsorption kinetic study of the interaction between human salivary alpha-amylase and the polyphenoles from the black/green tea].
Topics: Adsorption; alpha-Amylases; Animals; Antioxidants; Biflavonoids; Catechin; Chlorocebus aethiops; Humans; Salivary alpha-Amylases; Tea | 2011 |
Ascorbic acid offsets the inhibitory effect of bioactive dietary polyphenolic compounds on transepithelial iron transport in Caco-2 intestinal cells.
Topics: Ascorbic Acid; Biological Transport; Caco-2 Cells; Catechin; Cation Transport Proteins; Cell Polarity; Cold Temperature; Diet; Dietary Supplements; Enterocytes; Flavonoids; Grape Seed Extract; Humans; Intestinal Absorption; Iron Chelating Agents; Iron Radioisotopes; Iron, Dietary; Oxidation-Reduction; Phenols; Plant Extracts; Polyphenols; Tea | 2011 |
(-)-Epigallocatechin-3-O-gallate induces nonapoptotic cell death in leukemia cells independent of the 67 kDa laminin receptor.
Topics: Apoptosis; Caspase 3; Catechin; HL-60 Cells; Humans; K562 Cells; Lymphoma, Non-Hodgkin; Molecular Structure; Reactive Oxygen Species; Receptors, Laminin; Stereoisomerism | 2011 |
Prolonged exposure of cortical neurons to oligomeric amyloid-β impairs NMDA receptor function via NADPH oxidase-mediated ROS production: protective effect of green tea (-)-epigallocatechin-3-gallate.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Arachidonic Acid; Calcium; Catechin; Cell Survival; Cells, Cultured; Cerebral Cortex; Drug Interactions; Embryo, Mammalian; Glycoproteins; L-Lactate Dehydrogenase; N-Methylaspartate; NADPH Oxidases; Neurons; Neuroprotective Agents; Oxazines; Peptide Fragments; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Xanthenes | 2011 |
Effect of green tea on pharmacokinetics of 5-fluorouracil in rats and pharmacodynamics in human cell lines in vitro.
Topics: Animals; Antimetabolites, Antineoplastic; Area Under Curve; Camellia sinensis; Catechin; Cell Line, Tumor; Cell Survival; Drug Synergism; Fluorouracil; Humans; Male; Neoplasms; Plant Extracts; Rats; Rats, Sprague-Dawley | 2011 |
Nicotinic acetylcholine receptor-based blockade: applications of molecular targets for cancer therapy.
Topics: Aconitine; Anticarcinogenic Agents; Catechin; Humans; Molecular Targeted Therapy; Neoplasms; Nicotinic Antagonists; Receptors, Nicotinic; Signal Transduction; Smoking; Terpenes | 2011 |
Epigallocatechin-gallate stimulates NF-E2-related factor and heme oxygenase-1 via caveolin-1 displacement.
Topics: Animals; Bilirubin; Catechin; Caveolae; Caveolin 1; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Heme Oxygenase-1; NF-E2-Related Factor 2; RNA, Small Interfering; Swine | 2012 |
Epigallocatechin-3-gallate does not affect the activity of enzymes involved in metabolic activation and cellular excretion of benzo[a]pyrene in human colon carcinoma cells.
Topics: Benzo(a)pyrene; Biotransformation; Caco-2 Cells; Catechin; Cytochrome P-450 CYP1A1; Flavonoids; Flavonols; Glucuronosyltransferase; Humans; Receptors, Aryl Hydrocarbon; RNA, Messenger | 2011 |
Evaluation of renal protective effects of the green-tea (EGCG) and red grape resveratrol: role of oxidative stress and inflammatory cytokines.
Topics: Animals; Camellia sinensis; Catechin; Cisplatin; Cross-Linking Reagents; Cytokines; Dose-Response Relationship, Drug; Gene Expression Regulation; Kidney Diseases; Lipid Peroxidation; Oxidative Stress; Rats; Resveratrol; Stilbenes; Vitis | 2011 |
Epigallocatechin gallate inhibits HBV DNA synthesis in a viral replication - inducible cell line.
Topics: Antiviral Agents; Catechin; DNA Replication; DNA, Viral; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Viral; Genes, Reporter; Hep G2 Cells; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Viral; Transcription, Genetic; Transfection; Virus Replication | 2011 |
SU5416 and EGCG work synergistically and inhibit angiogenic and survival factors and induce cell cycle arrest to promote apoptosis in human malignant neuroblastoma SH-SY5Y and SK-N-BE2 cells.
Topics: Angiogenesis Inhibitors; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; E2F1 Transcription Factor; Humans; In Situ Nick-End Labeling; Indoles; Neovascularization, Pathologic; Neuroblastoma; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Retinoblastoma Protein; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2011 |
No inhibitory effects of (-)-epigallocatechin gallate and lycopene on spontaneous hepatotumorigenesis in C3H/HeN mice.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Carotenoids; Catechin; Liver Neoplasms, Experimental; Lycopene; Male; Mice; Mice, Inbred C3H; Mice, Knockout; Xeroderma Pigmentosum Group A Protein | 2010 |
In vitro antifungal activity of epigallocatechin 3-O-gallate against clinical isolates of dermatophytes.
Topics: Antifungal Agents; Arthrodermataceae; Catechin; Microbial Sensitivity Tests | 2011 |
Bioactive components from the tea polyphenols influence on endogenous antioxidant defense system and modulate inflammatory cytokines after total-body irradiation in mice.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Catechin; Gamma Rays; Hematologic Agents; Interleukin-1beta; Interleukin-6; Leukopenia; Malondialdehyde; Mice; Molecular Structure; Polyphenols; Radiation Injuries; Radiation-Protective Agents; Superoxide Dismutase; Tea; Tumor Necrosis Factor-alpha; Whole-Body Irradiation | 2011 |
A case report of atrial fibrillation potentially induced by hydroxycut: a multicomponent dietary weight loss supplement devoid of sympathomimetic amines.
Topics: Anti-Obesity Agents; Atrial Fibrillation; Catechin; Dietary Supplements; Female; Humans; Middle Aged; Plant Preparations; Sympathomimetics | 2010 |
Synergism from sequenced combinations of curcumin and epigallocatechin-3-gallate with cisplatin in the killing of human ovarian cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Catechin; Cisplatin; Curcumin; DNA Adducts; Drug Synergism; Female; Humans; Ovarian Neoplasms; Tumor Cells, Cultured | 2011 |
Epigallocatechin-3-O-gallate (EGCG) attenuates FFAs-induced peripheral insulin resistance through AMPK pathway and insulin signaling pathway in vivo.
Topics: AMP-Activated Protein Kinases; Animals; Catechin; Drug Therapy, Combination; Fatty Acids, Nonesterified; Glucose Clamp Technique; Insulin; Insulin Resistance; Oxidative Stress; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; Signal Transduction | 2011 |
Epigallocatechin-3-gallate regulates cell growth, cell cycle and phosphorylated nuclear factor-κB in human dermal fibroblasts.
Topics: Antioxidants; Apoptosis; Camellia sinensis; Catechin; Cell Cycle; Cell Proliferation; Cells, Cultured; Cytoplasm; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation; Humans; Infant, Newborn; NF-kappa B; Oligonucleotide Array Sequence Analysis; Phosphorylation; Skin | 2011 |
Therapeutic potential of dietary polyphenols against brain ageing and neurodegenerative disorders.
Topics: Aging; Antioxidants; Brain; Caffeic Acids; Catechin; Curcumin; Diet; Flavonoids; Neurodegenerative Diseases; Neuroprotective Agents; Phenols; Phenylethyl Alcohol; Polyphenols | 2010 |
Effect of girdling at various positions of 'Huang Zhi Xiang' tea tree (Camellia sinensis) on the contents of catechins and starch in fresh leaf.
Topics: Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Plant Leaves; Starch | 2011 |
Lipophilized epigallocatechin gallate (EGCG) derivatives as novel antioxidants.
Topics: Antioxidants; Camellia sinensis; Catechin; Fatty Acids; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Plant Extracts; Solubility | 2011 |
The green tea polyphenol (-)-epigallocatechin-3-gallate ameliorates experimental immune-mediated glomerulonephritis.
Topics: Animals; Anti-Glomerular Basement Membrane Disease; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Catechin; Kidney; Male; Mice; Mice, 129 Strain; NF-kappa B; Nitric Oxide; Osteopontin; Oxidative Stress; PPAR gamma; Signal Transduction; Tea | 2011 |
Difference of EGCg adhesion on cell surface between Staphylococcus aureus and Escherichia coli visualized by electron microscopy after novel indirect staining with cerium chloride.
Topics: Catechin; Cerium; Coloring Agents; Escherichia coli; Microscopy, Electron; Staining and Labeling; Staphylococcus aureus | 2011 |
Production of monodisperse epigallocatechin gallate (EGCG) microparticles by spray drying for high antioxidant activity retention.
Topics: Anticarcinogenic Agents; Antioxidants; Catechin; Desiccation; Drug Compounding; Drug Delivery Systems; Excipients; Fluoresceins; Free Radical Scavengers; Hot Temperature; Hypromellose Derivatives; Lactose; Methylcellulose; Nanoparticles; Particle Size; Pharmaceutical Solutions; Powders | 2011 |
Metabolite modulation of HeLa cell response to ENOX2 inhibitors EGCG and phenoxodiol.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Membrane; Cell Survival; Enzyme Inhibitors; HeLa Cells; Humans; Isoflavones; Lysophospholipids; NADH, NADPH Oxidoreductases; NADP; Sphingosine | 2011 |
Implantation of green tea catechin α-tricalcium phosphate combination enhances bone repair in rat skull defects.
Topics: Animals; Bone Regeneration; Calcium Phosphates; Catechin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Male; Rats; Rats, Wistar; Skull; Treatment Outcome | 2011 |
Synergistic anti-bacterial and proteomic effects of epigallocatechin gallate on clinical isolates of imipenem-resistant Klebsiella pneumoniae.
Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Catechin; Drug Resistance, Bacterial; Drug Synergism; Electrophoresis, Polyacrylamide Gel; Imipenem; Klebsiella pneumoniae; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Proteomics; Tea | 2011 |
Epigallocatechin gallate accelerates healing of indomethacin-induced stomach ulcers in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Catechin; Disease Models, Animal; Gastric Mucosa; Indomethacin; Lipid Peroxidation; Male; Mice; Omeprazole; Oxidative Stress; Stomach Ulcer; Tea | 2011 |
Early transcriptional pattern of angiogenesis induced by EGCG treatment in cervical tumour cells.
Topics: Angiogenesis Inhibitors; Apoptosis; Catechin; Cell Adhesion; Cell Movement; Cell Proliferation; Collagen; Drug Combinations; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HeLa Cells; Human Umbilical Vein Endothelial Cells; Humans; Laminin; Neoplasm Invasiveness; Neovascularization, Pathologic; Proteoglycans; Signal Transduction; Transcription, Genetic; Uterine Cervical Neoplasms | 2012 |
Chemopreventive effect of epigallocatechin-3-gallate (EGCG) and folic acid on the N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced gastrointestinal cancer in rat model.
Topics: Adenocarcinoma; Administration, Oral; Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Proliferation; Disease Models, Animal; Drug Therapy, Combination; Folic Acid; Gastrointestinal Neoplasms; Hematinics; Male; Methylnitronitrosoguanidine; Rats; Rats, Wistar; Sarcoma; Treatment Outcome | 2011 |
Induction of regulatory T cells by green tea polyphenol EGCG.
Topics: Animals; Catechin; Cell Line, Tumor; Cytokines; DNA Methylation; DNA Modification Methylases; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Interleukin-10; Jurkat Cells; Male; Mice; Mice, Inbred BALB C; Polyphenols; T-Lymphocytes; T-Lymphocytes, Regulatory; Tea | 2011 |
(-)-Epigallocatechin gallate attenuates NADPH-d/nNOS expression in motor neurons of rats following peripheral nerve injury.
Topics: Animals; Brain Stem; Catechin; Cell Death; Dose-Response Relationship, Drug; Male; Motor Neurons; NADP; Nerve Crush; Neuroprotective Agents; Nitric Oxide Synthase Type I; Peripheral Nerve Injuries; Rats; Rats, Wistar | 2011 |
Inverse relationship between adipocyte differentiation and ceramide level in 3T3-L1 cells.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Catechin; Ceramides; Lipid Metabolism; Mice; Molecular Targeted Therapy; Obesity; Sphingosine; Triglycerides | 2011 |
Inhibitory effect of (-)-epigallocatechin gallate on titanium particle-induced TNF-α release and in vivo osteolysis.
Topics: Animals; Catechin; Cell Line; Implants, Experimental; Macrophages; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 8; NF-kappa B; Osteolysis; Particulate Matter; Prosthesis Failure; Signal Transduction; Skull; Titanium; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2011 |
(-)-Epigallocatechin-3-gallate inhibits pancreatic lipase and reduces body weight gain in high fat-fed obese mice.
Topics: Animals; Antioxidants; Body Weight; Catechin; Diet, High-Fat; Feces; Lipase; Lipids; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity | 2012 |
(-)-Epigallocatechin-3-gallate inhibits VEGF expression induced by IL-6 via Stat3 in gastric cancer.
Topics: Anticarcinogenic Agents; Blotting, Western; Catechin; Cell Proliferation; Chromatin Immunoprecipitation; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Humans; In Vitro Techniques; Interleukin-6; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Stomach Neoplasms; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2011 |
Attenuation of the cardiac inflammatory changes and lipid anomalies by (-)-epigallocatechin-gallate in cigarette smoke-exposed rats.
Topics: Animals; Antioxidants; Catechin; Cholesterol; Creatine Kinase; Cyclooxygenase 2; Heart; Isoenzymes; L-Lactate Dehydrogenase; Lipid Metabolism; Lipids; Male; Myocarditis; Myocardium; NF-kappa B; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Smoking; Tumor Necrosis Factor-alpha | 2011 |
Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation.
Topics: Animals; Antioxidants; Carrier Proteins; Catechin; Disease Progression; Gene Expression Regulation; Inflammasomes; Interleukin-18; Interleukin-1beta; Kidney; Lupus Nephritis; Mice; Mice, Inbred NZB; NF-E2-Related Factor 2; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress | 2011 |
In vitro screening of synergistic ascorbate-drug combinations for the treatment of malignant mesothelioma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; L-Lactate Dehydrogenase; Lung Neoplasms; Mesothelioma; Neutral Red | 2011 |
Epigallocatechin-3-gallate induced modulation of cell deadhesion and migration on thermosensitive poly(N-isopropylacrylamide).
Topics: Acrylamides; Acrylic Resins; Anticarcinogenic Agents; Biocompatible Materials; Catechin; Cell Adhesion; Cell Movement; Hep G2 Cells; Humans; Liver Neoplasms; Polymers; Tea; Temperature | 2011 |
Green tea extract (epigallocatechin-3-gallate) reduces efficacy of radiotherapy on prostate cancer cells.
Topics: Antioxidants; Catechin; Humans; Male; Plant Extracts; Prostatic Neoplasms; Tea; Treatment Outcome; Tumor Cells, Cultured | 2011 |
Epigallocatechin-3-gallate suppresses the global interleukin-1beta-induced inflammatory response in human chondrocytes.
Topics: Aged; Antioxidants; Catechin; Chondrocytes; Cytoprotection; Drug Interactions; Gene Expression; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-1 Receptor-Associated Kinases; Interleukin-1beta; Interleukin-6; Interleukin-8; MAP Kinase Signaling System; Middle Aged; NF-kappa B; Nitrites; Osteoarthritis; Primary Cell Culture; TNF Receptor-Associated Factor 6; Tumor Necrosis Factor-alpha | 2011 |
A comparative study of the inhibiting effects of mitomycin C and polyphenolic catechins on tumor cell implantation/growth in a rat bladder tumor model.
Topics: Animals; Antibiotics, Antineoplastic; Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Screening Assays, Antitumor; Female; Mitomycin; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 2011 |
Dietary supplementation with high dose of epigallocatechin-3-gallate promotes inflammatory response in mice.
Topics: Animals; Biomarkers; Catechin; Dietary Supplements; Dinoprostone; Inflammation; Interleukin-1beta; Interleukin-6; Killer Cells, Natural; Male; Mice; Mice, Inbred C57BL; Natural Killer T-Cells; Plant Extracts; Spleen; Tea; Tumor Necrosis Factor-alpha | 2012 |
[The study of apoptosis of hepatocytes of rats for estimation safety and efficacy of application biologically active substances].
Topics: Animals; Antioxidants; Apoptosis; Caffeine; Catechin; Cells, Cultured; Central Nervous System Stimulants; Drug Evaluation; Food Additives; Hepatocytes; Male; Quercetin; Rats; Rats, Wistar | 2011 |
Green tea epigallocatechin-3-gallate (EGCG) and other flavonoids reduce Alzheimer's amyloid-induced mitochondrial dysfunction.
Topics: Adenosine Triphosphate; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Blotting, Western; Brain; Catechin; Cell Line, Tumor; Cerebral Cortex; Corpus Striatum; Enzyme-Linked Immunosorbent Assay; Flavonoids; Hippocampus; Humans; In Vitro Techniques; Membrane Potentials; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Diseases; Oxygen Consumption; Reactive Oxygen Species | 2011 |
Inhibitory effect of Epigallocatechin gallate on ovarian cancer cell proliferation associated with aquaporin 5 expression.
Topics: Analysis of Variance; Anticarcinogenic Agents; Antioxidants; Apoptosis; Aquaporin 5; Catechin; Cell Line, Tumor; Cell Membrane; Cell Nucleus; Cell Proliferation; Cytoplasm; Dose-Response Relationship, Drug; Down-Regulation; Female; Humans; I-kappa B Proteins; NF-KappaB Inhibitor alpha; Ovarian Neoplasms; Pyrrolidines; RNA, Messenger; Thiocarbamates; Transcription Factor RelA | 2012 |
Chronic epigallocatechin-3-gallate ameliorates learning and memory deficits in diabetic rats via modulation of nitric oxide and oxidative stress.
Topics: Animals; Avoidance Learning; Blood Glucose; Body Weight; Catechin; Diabetes Mellitus, Experimental; Hippocampus; Indazoles; Learning Disabilities; Male; Malondialdehyde; Maze Learning; Memory Disorders; Nerve Tissue Proteins; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitrites; Oxidative Stress; Rats; Rats, Wistar | 2011 |
EGCG-meditated cyto- and genotoxicity in HaCat keratinocytes is impaired by cell-mediated clearance of auto-oxidation-derived H2O2: an algorithm for experimental setting correction.
Topics: Algorithms; Blotting, Western; Catechin; Cell Count; Cell Culture Techniques; Cell Line; Cell Survival; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Humans; Hydrogen Peroxide; Keratinocytes; Mutagens; Oxidation-Reduction; Oxidative Stress; Time Factors; Toxicity Tests | 2011 |
Genotoxic effects of green tea extract on human laryngeal carcinoma cells in vitro.
Topics: Camellia sinensis; Catechin; Cell Line, Tumor; Comet Assay; DNA Damage; Humans; Laryngeal Neoplasms; Lipid Peroxidation; Mutagens; Plant Extracts; Tea; Tumor Cells, Cultured | 2011 |
Anti-inflammatory effect of the epigallocatechin gallate following spinal cord trauma in rat.
Topics: Animals; Anti-Inflammatory Agents; Catechin; Cyclooxygenase 2; Densitometry; Immunohistochemistry; Interleukin-1beta; Male; Myelin Sheath; Neutrophil Infiltration; Nitric Oxide Synthase Type II; Peroxidase; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Tumor Necrosis Factor-alpha; Tyrosine | 2011 |
Epigallocatechin-3-gallate induces growth inhibition and apoptosis of human anaplastic thyroid carcinoma cells through suppression of EGFR/ERK pathway and cyclin B1/CDK1 complex.
Topics: Anticarcinogenic Agents; Apoptosis; Carcinoma; Catechin; CDC2 Protein Kinase; Cell Line, Tumor; Cell Proliferation; Cyclin B1; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Humans; Signal Transduction; Thyroid Neoplasms | 2011 |
[Effects of loaded buffer with epigallocatechin gallate on physiological functions of platelets].
Topics: Apoptosis; Blood Platelets; Catechin; Flow Cytometry; Humans; Platelet Aggregation; Platelet Count | 2011 |
Epigallocatechin gallate inhibits the HIV reverse transcription step.
Topics: Anti-HIV Agents; Catechin; Drug Evaluation, Preclinical; Drug Synergism; HeLa Cells; HIV Infections; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Reverse Transcriptase Inhibitors; Reverse Transcription; Uracil; Zidovudine | 2011 |
Natural polyphenols inhibit different steps of the process of transthyretin (TTR) amyloid fibril formation.
Topics: Amyloid; Amyloidosis; Catechin; Curcumin; Flavonoids; Phenols; Polyphenols; Prealbumin; Protein Binding; Protein Multimerization | 2011 |
Attenuated mitochondrial NADP+-dependent isocitrate dehydrogenase activity enhances EGCG-induced apoptosis.
Topics: Apoptosis; Catechin; Cell Line, Tumor; DNA Fragmentation; HCT116 Cells; HeLa Cells; Humans; Immunoblotting; Isocitrate Dehydrogenase; Mitochondria; Mutagenesis, Site-Directed; RNA, Small Interfering | 2011 |
Proteomic approaches to study epigallocatechin gallate-provoked apoptosis of TSGH-8301 human urinary bladder carcinoma cells: roles of AKT and heat shock protein 27-modulated intrinsic apoptotic pathways.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Line, Tumor; HSP27 Heat-Shock Proteins; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Proteomics; Proto-Oncogene Proteins c-akt; Random Allocation; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays | 2011 |
Epigallocatechin-gallate suppresses tumorigenesis by directly targeting Pin1.
Topics: Animals; Catechin; Cyclin D1; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Humans; Mice; Mice, Knockout; Mice, Nude; Neoplasm Transplantation; NF-kappa B; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Protein Structure, Tertiary; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2011 |
Acute effects of epigallocatechin gallate from green tea on oxidation and tissue incorporation of dietary lipids in mice fed a high-fat diet.
Topics: Adipose Tissue; Animals; Antioxidants; Body Composition; Catechin; Diet, High-Fat; Dietary Supplements; Eating; Intestinal Absorption; Intestinal Mucosa; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction; Tea | 2012 |
Investigating the hydrogen peroxide quenching capacity of proteins in polyphenol-rich foods.
Topics: Antioxidants; Catechin; Dietary Proteins; Emulsions; Hydrogen Peroxide; Oxidation-Reduction; Polyphenols; Reactive Oxygen Species | 2011 |
Tea polyphenols induce apoptosis through mitochondrial pathway and by inhibiting nuclear factor-kappaB and Akt activation in human cervical cancer cells.
Topics: Apoptosis; Biflavonoids; Blotting, Western; Catechin; Cell Cycle; Cell Proliferation; Dose-Response Relationship, Drug; Female; Flavonoids; HeLa Cells; Humans; Membrane Potential, Mitochondrial; Mitochondria; NF-kappa B; Phenols; Polyphenols; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Tea; Time Factors; Tumor Cells, Cultured | 2011 |
(-)-Epigallocatechin-3-gallate increases the expression of genes related to fat oxidation in the skeletal muscle of high fat-fed mice.
Topics: Adipose Tissue; Animals; Antioxidants; Cadherins; Catechin; Diet, High-Fat; Dietary Fats; Gene Expression; Ion Channels; Male; Mice; Mice, Inbred C57BL; Mitochondrial Proteins; Muscle, Skeletal; Nuclear Respiratory Factor 1; Obesity; Oxidation-Reduction; PPAR alpha; Uncoupling Protein 3; Weight Gain | 2011 |
Role of the COX-independent pathways in the ulcer-healing action of epigallocatechin gallate.
Topics: Animals; Anti-Ulcer Agents; Catechin; Gene Expression Regulation; Intercellular Adhesion Molecule-1; Interleukin-10; Interleukin-4; Interleukin-6; Male; Mice; Nitric Oxide Synthase Type II; Nitrites; Omeprazole; Peroxidase; Selectins; Signal Transduction; Stomach Ulcer; Tumor Necrosis Factor-alpha; Ulcer; Vascular Cell Adhesion Molecule-1 | 2011 |
The treatment of bladder cancer in a mouse model by epigallocatechin-3-gallate-gold nanoparticles.
Topics: Animals; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Gold; Immunologic Factors; Male; Mice; Nanoparticles; Tea; Urinary Bladder Neoplasms | 2011 |
EGCG disaggregates amyloid-like fibrils formed by Plasmodium falciparum merozoite surface protein 2.
Topics: Amyloid; Antigens, Protozoan; Biophysical Phenomena; Catechin; Flavonoids; Malaria Vaccines; Merozoites; Microscopy, Electron, Transmission; Plasmodium falciparum; Protein Multimerization; Protein Structure, Secondary; Protozoan Proteins | 2011 |
Green tea epigallo-catechin-galleate ameliorates the development of obliterative airway disease.
Topics: Animals; Bronchiolitis Obliterans; Catechin; Cytokines; Fibrosis; Inflammation; Lung Transplantation; Mice; Neutrophil Infiltration; Tea | 2011 |
EGCG downregulates IL-1RI expression and suppresses IL-1-induced tumorigenic factors in human pancreatic adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Catechin; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Interleukin-1; Matrix Metalloproteinase 2; Pancreatic Neoplasms; Receptors, Interleukin-1 Type I; Vascular Endothelial Growth Factor A | 2011 |
Tea polyphenol-induced neuron-like differentiation of mouse mesenchymal stem cells.
Topics: Animals; Bone Marrow Cells; Catechin; Cell Differentiation; Cells, Cultured; Gene Expression; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Neurogenesis; Neurons; Neuroprotective Agents; Tea | 2011 |
The anti-cancer effects of (-)-epigallocatechin-3-gallate on the signaling pathways associated with membrane receptors in MCF-7 cells.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Calcium; Catechin; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Humans; Membrane Proteins; Signal Transduction | 2011 |
Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics.
Topics: Apoptosis; Caspase 3; Catechin; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Epithelial-Mesenchymal Transition; Hedgehog Proteins; Homeodomain Proteins; Humans; Nanog Homeobox Protein; Neoplastic Stem Cells; Octamer Transcription Factor-3; Pancreatic Neoplasms; Plant Extracts; Pluripotent Stem Cells; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Quercetin; Signal Transduction; TCF Transcription Factors; Tea; Transcription, Genetic; X-Linked Inhibitor of Apoptosis Protein | 2012 |
Epigallocatechin-3-gallate protects rat brain mitochondria against cadmium-induced damage.
Topics: Animals; Brain; Cadmium; Catechin; Chelating Agents; Formazans; Glutathione; Male; Mitochondria; Neuroprotective Agents; Rats; Rats, Wistar; Tetrazolium Salts; Thiobarbituric Acid Reactive Substances | 2011 |
(-)-Epigallocatechin-3-gallate and DZNep reduce polycomb protein level via a proteasome-dependent mechanism in skin cancer cells.
Topics: Acetylation; Adenosine; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Carrier Proteins; Caspases; Catechin; Cell Cycle; Cell Proliferation; Cells, Cultured; DNA Methylation; DNA-Binding Proteins; Drug Synergism; Enhancer of Zeste Homolog 2 Protein; Histone Deacetylase 1; Histones; Humans; Keratinocytes; Membrane Potential, Mitochondrial; Neoplasm Proteins; Nuclear Proteins; Polycomb Repressive Complex 1; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins; Repressor Proteins; Skin Neoplasms; Transcription Factors; Ubiquitination | 2011 |
Chrysin restores PDGF-induced inhibition on protein tyrosine phosphatase and reduces PDGF signaling in cultured VSMCs.
Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Catechin; Cell Proliferation; Flavonoids; Glutathione; Hydrogen Peroxide; Hyperplasia; Muscle, Smooth, Vascular; NADPH Oxidases; Neointima; Phosphorylation; Platelet-Derived Growth Factor; Protein Tyrosine Phosphatases; Rats; Reactive Oxygen Species; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Tunica Intima; Vanadates | 2012 |
Photodegradation of (-)-epigallocatechin-3-gallate in topical cream formulations and its photostabilization.
Topics: Administration, Topical; Alkanes; Antioxidants; Benzophenones; Catechin; Chalcones; Cinnamates; Drug Compounding; Drug Stability; Emollients; Emulsions; Excipients; Humans; Photolysis; Propiophenones; Reproducibility of Results; Skin; Sunscreening Agents; Tea; Ultraviolet Rays | 2011 |
[Effect of epigallocatechin gallate on lactacystin-induced PC12 cell injury].
Topics: Acetylcysteine; Animals; Apoptosis; Catechin; Flow Cytometry; PC12 Cells; Rats | 2011 |
Green tea polyphenols control dysregulated glutamate dehydrogenase in transgenic mice by hijacking the ADP activation site.
Topics: Adenosine Diphosphate; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Catalytic Domain; Catechin; Glucose; Glutamate Dehydrogenase; Glutamine; Humans; Islets of Langerhans; Mice; Mice, Transgenic; Mutagenesis, Site-Directed; Rats; Tea | 2011 |
Epigallocatechin-3-gallate has dual, independent effects on the cardiac sarcoplasmic reticulum/endoplasmic reticulum Ca2+ ATPase.
Topics: Animals; Antioxidants; Calcium; Catechin; Dogs; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Myocardium; Myocytes, Cardiac; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2011 |
Enhanced autophagy plays a cardinal role in mitochondrial dysfunction in type 2 diabetic Goto-Kakizaki (GK) rats: ameliorating effects of (-)-epigallocatechin-3-gallate.
Topics: Animals; Autophagy; Blood Glucose; Catechin; Diabetes Mellitus, Type 2; Down-Regulation; Fasting; Hypoglycemic Agents; Insulin Resistance; Male; Mitochondria; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Oxidative Stress; Rats; Tumor Suppressor Protein p53; Up-Regulation | 2012 |
Epigallocatechin gallate ameliorates behavioral and biochemical deficits in rat model of load-induced chronic fatigue syndrome.
Topics: Animals; Behavior, Animal; Body Weight; Brain Chemistry; Catechin; Cognition; Drinking; Eating; Fatigue Syndrome, Chronic; Hyperalgesia; Male; Maze Learning; Motor Activity; Nitric Oxide; Organ Size; Oxidative Stress; Physical Endurance; Postural Balance; Psychomotor Performance; Rats; Rats, Wistar; Stress, Psychological; Tumor Necrosis Factor-alpha | 2011 |
Green tea epigallocatechin-3-gallate inhibits angiogenesis and suppresses vascular endothelial growth factor C/vascular endothelial growth factor receptor 2 expression and signaling in experimental endometriosis in vivo.
Topics: Adult; Animals; Catechin; Cells, Cultured; Endometriosis; Female; Gene Expression Regulation; Humans; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Random Allocation; Signal Transduction; Tea; Vascular Endothelial Growth Factor C; Vascular Endothelial Growth Factor Receptor-2 | 2011 |
Analysis of the mechanism of inhibition of human matrix metalloproteinase 7 (MMP-7) activity by green tea catechins.
Topics: Antioxidants; Calcium Chloride; Catechin; Chromogenic Compounds; Humans; Hydrogen-Ion Concentration; Hydrolysis; Matrix Metalloproteinase 7; Matrix Metalloproteinase Inhibitors; Oligopeptides; Recombinant Proteins; Spectrometry, Fluorescence; Structure-Activity Relationship; Tea | 2011 |
Epigallocatechin-3-O-gallate inhibits the production of thymic stromal lymphopoietin by the blockade of caspase-1/NF-κB pathway in mast cells.
Topics: Blotting, Western; Calcimycin; Caspase Inhibitors; Caspases; Catechin; Cell Line; Cytokines; Gene Expression; Genes, Reporter; Humans; Luciferases; Mast Cells; NF-kappa B; Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin | 2012 |
The green tea polyphenol, epigallocatechin-3-gallate, inhibits hepatitis C virus entry.
Topics: Catechin; Cell Line, Tumor; Cells, Cultured; Hepacivirus; Hepatitis C; Humans; Tea; Virus Attachment; Virus Internalization | 2011 |
[(-)-Epigallocatechin-3-gallate reduces vascular endothelial growth factor expression in gastric cancer cells via suppressing activity].
Topics: Catechin; Humans; Interleukin-6; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Stomach Neoplasms; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2011 |
[Inhibitory effect and mechanism of (-)-epigallocatechin-3-gallate on HT29 and HCT-8 colorectal cancer cell lines and expression of HES1 and JAG1].
Topics: Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Calcium-Binding Proteins; Catechin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Flow Cytometry; Homeodomain Proteins; HT29 Cells; Humans; Intercellular Signaling Peptides and Proteins; Jagged-1 Protein; Membrane Proteins; Serrate-Jagged Proteins; Transcription Factor HES-1 | 2011 |
Occlusion of dentin tubules with antibacterial ammonium hexafluorosilicate solution for the prevention of dentin caries.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Antioxidants; Cariostatic Agents; Catechin; Cetylpyridinium; Chelating Agents; Chemical Precipitation; Chlorhexidine; Dental Caries; Dentin; Edetic Acid; Fluorides; Humans; Hydrogen-Ion Concentration; Materials Testing; Microscopy, Electron, Scanning; Phenols; Saliva, Artificial; Silicic Acid; Smear Layer; Temperature; Time Factors | 2011 |
Glomerulonephritis therapy: is there a role for green tea?
Topics: Animals; Anti-Glomerular Basement Membrane Disease; Catechin; Male; Tea | 2011 |
Biomimetic one-pot preparation of a black tea polyphenol theasinensin A from epigallocatechin gallate by treatment with copper(II) chloride and ascorbic acid.
Topics: Ascorbic Acid; Benzopyrans; Biomimetic Materials; Catechin; Copper; Dimerization; Oxidation-Reduction; Phenols; Polyphenols; Stereoisomerism; Tea | 2011 |
(-)-epigallocatechin-3-O-gallate augments pentobarbital-induced sleeping behaviors through Cl- channel activation.
Topics: Animals; Catechin; Cells, Cultured; Cerebellum; Chloride Channels; Chlorides; Glutamate Decarboxylase; Hippocampus; Male; Mice; Mice, Inbred ICR; Muscimol; Neuroprotective Agents; Pentobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA; Sleep | 2011 |
Effect of supplementation of soft drinks with green tea extract on their erosive potential against dentine.
Topics: Animals; Camellia sinensis; Carbonated Beverages; Catechin; Cattle; Dentin; Dietary Supplements; Hardness; Hydrogen-Ion Concentration; Materials Testing; Matrix Metalloproteinase Inhibitors; Plant Extracts; Saliva, Artificial; Temperature; Time Factors; Tooth Demineralization; Tooth Erosion; Tooth Remineralization | 2011 |
Green tea polyphenol epigallocatechin gallate activates TRPA1 in an intestinal enteroendocrine cell line, STC-1.
Topics: 3T3 Cells; Animals; Antioxidants; Calcium; Calcium Channel Blockers; Catechin; Cell Line; Enteroendocrine Cells; HEK293 Cells; Humans; Intestines; Mice; Microscopy, Fluorescence; Polyphenols; Taste; Taste Perception; Tea; Transfection; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2012 |
Green tea gets molecular.
Topics: Animals; Anticarcinogenic Agents; Catechin; Fibroblasts; Humans; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Knockout; Models, Chemical; Neoplasms; NF-kappa B; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Tea; Transcription Factor AP-1; Transcription, Genetic | 2011 |
Effects of green tea catechins on gramicidin channel function and inferred changes in bilayer properties.
Topics: Antioxidants; Catechin; Gramicidin; Humans; Ion Channel Gating; Ion Channels; Lipid Bilayers; Molecular Structure; Tea | 2011 |
Cytotoxicity of gamma-ray in rat immature hippocampal neurons.
Topics: Amifostine; Animals; Antioxidants; Caspase 3; Catechin; Cell Survival; Cells, Cultured; Dose-Response Relationship, Radiation; Female; Gamma Rays; Hippocampus; L-Lactate Dehydrogenase; Neurons; Poly(ADP-ribose) Polymerases; Pregnancy; Rats; Rats, Sprague-Dawley | 2011 |
Molecular insight into conformational transition of amyloid β-peptide 42 inhibited by (-)-epigallocatechin-3-gallate probed by molecular simulations.
Topics: Amyloid beta-Peptides; Catechin; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Peptide Fragments; Protein Binding; Thermodynamics | 2011 |
(-)-Epigallocatechin gallate suppresses adipocyte differentiation through the MEK/ERK and PI3K/Akt pathways.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Catechin; CCAAT-Enhancer-Binding Protein-alpha; Cell Differentiation; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Forkhead Box Protein O1; Forkhead Transcription Factors; Hypoglycemic Agents; Mice; Mitogen-Activated Protein Kinase Kinases; Phosphatidylinositol 3-Kinases; PPAR gamma; Proto-Oncogene Proteins c-akt; S Phase; Signal Transduction; Transcription, Genetic | 2012 |
The effects of gold nanoparticles in wound healing with antioxidant epigallocatechin gallate and α-lipoic acid.
Topics: Animals; Antioxidants; Catechin; Cell Movement; Cell Proliferation; Gene Expression; Gold; Humans; Mice; Mice, Inbred BALB C; Nanoparticles; Neovascularization, Physiologic; Ribonuclease, Pancreatic; Skin; Thioctic Acid; Vascular Endothelial Growth Factor A; Wound Healing | 2012 |
EGCG protects against UVB-induced apoptosis via oxidative stress and the JNK1/c-Jun pathway in ARPE19 cells.
Topics: Anisomycin; Anti-Bacterial Agents; Apoptosis; Catechin; Cell Line; Epithelial Cells; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 8; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Ultraviolet Rays | 2012 |
Epigallocatechin gallate inhibits sphere formation of neuroblastoma BE(2)-C cells.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Humans; Neuroblastoma; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction | 2012 |
Epigallocatechin-3-gallate protects pro-inflammatory cytokine induced injuries in insulin-producing cells through the mitochondrial pathway.
Topics: Adenosine Triphosphate; bcl-2-Associated X Protein; Catechin; Cell Death; Cell Line; Cytochromes c; Cytokines; Down-Regulation; Gene Expression Regulation, Enzymologic; Inflammation; Insulin; Insulin Secretion; Insulin-Secreting Cells; Membrane Potential, Mitochondrial; Mitochondria; Nitric Oxide; Nitric Oxide Synthase Type II; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Signal Transduction | 2011 |
Chitosan nanoparticles enhance the plasma exposure of (-)-epigallocatechin gallate in mice through an enhancement in intestinal stability.
Topics: Administration, Oral; Animals; Catechin; Chitosan; Chromatography, High Pressure Liquid; Drug Carriers; Drug Compounding; Drug Stability; Gastric Mucosa; Intestinal Absorption; Jejunum; Male; Mice; Molecular Structure; Mouth Mucosa; Nanoparticles; Tissue Distribution | 2011 |
Optimization of informative spectral variables for the quantification of EGCG in green tea using Fourier transform near-infrared (FT-NIR) spectroscopy and multivariate calibration.
Topics: Algorithms; Calibration; Catechin; Least-Squares Analysis; Multivariate Analysis; Spectroscopy, Fourier Transform Infrared; Spectroscopy, Near-Infrared; Tea | 2011 |
Effects of green tea polyphenol (-)-epigallocatechin-3-gallate on newly developed high-fat/Western-style diet-induced obesity and metabolic syndrome in mice.
Topics: Animals; Blood Glucose; Body Weight; Catechin; Diet, High-Fat; Disease Models, Animal; Humans; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Obesity; Plant Extracts; Polyphenols | 2011 |
Epigallocatechin-3-gallate induces cytokine production in mast cells by stimulating an extracellular superoxide-mediated calcium influx.
Topics: Animals; Bone Marrow Cells; Calcium; Calcium Signaling; Catechin; Cell Degranulation; Cell Line, Tumor; Cytokines; Gene Expression Regulation; Mast Cells; Mice; Rats; Superoxides | 2011 |
Digallate dimers of (-)-epigallocatechin gallate inactivate herpes simplex virus.
Topics: Animals; Antiviral Agents; Benzopyrans; Catechin; Chlorocebus aethiops; Depsides; Dimerization; Gallic Acid; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Hydrogen-Ion Concentration; Microscopy, Electron; Phenols; Vero Cells; Virus Inactivation | 2011 |
Effects of topical application of EGCG on testosterone-induced hair loss in a mouse model.
Topics: 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Alopecia; Animals; Antioxidants; Apoptosis; Catechin; Cyproterone Acetate; Dihydrotestosterone; Disease Models, Animal; Down-Regulation; Epithelial Cells; Female; Hair; Hair Follicle; Mice; Mice, Inbred CBA; Receptors, Androgen; Sebaceous Glands; Testosterone | 2011 |
Thrombin-stimulated connective tissue growth factor (CTGF/CCN2) production in human buccal mucosal fibroblasts: Inhibition by epigallocatechin-3-gallate.
Topics: Amino Acid Chloromethyl Ketones; Anticarcinogenic Agents; Areca; Blotting, Western; Catechin; Cells, Cultured; Connective Tissue Growth Factor; Fibroblasts; Hemostatics; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinase 5; Mastication; Mouth Mucosa; Oral Submucous Fibrosis; Reactive Oxygen Species; Receptor, PAR-1; Serine Proteinase Inhibitors; Thrombin; Up-Regulation | 2012 |
A comparative reverse docking strategy to identify potential antineoplastic targets of tea functional components and binding mode.
Topics: Antineoplastic Agents; Catechin; Computer Simulation; Drug Discovery; Epoxide Hydrolases; Humans; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Polyphenols; Protein Binding; Quantitative Structure-Activity Relationship; Tea | 2011 |
(-)-Epigallocatechin gallate inhibits hepatitis C virus (HCV) viral protein NS5B.
Topics: Antiviral Agents; Catechin; Hepacivirus; Microscopy, Confocal; RNA; Viral Nonstructural Proteins | 2011 |
Epigallocatechin gallate (EGCG) inhibits type II phosphatidylinositol 4-kinases: a key component in pathways of phosphoinositide turnover.
Topics: 1-Phosphatidylinositol 4-Kinase; Amino Acid Sequence; Anticarcinogenic Agents; Binding Sites; Camellia sinensis; Catechin; Enzyme Inhibitors; Humans; Jurkat Cells; Models, Molecular; Molecular Sequence Data; Neoplasms; Phosphatidylinositols; Protein Binding; Protein Isoforms; Sequence Alignment | 2011 |
Green tea polyphenol EGCG suppresses lung cancer cell growth through upregulating miR-210 expression caused by stabilizing HIF-1α.
Topics: Animals; Blotting, Western; Catechin; Cell Division; Cell Line, Tumor; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoprecipitation; Lung Neoplasms; Mice; MicroRNAs; Tea; Up-Regulation | 2011 |
(-)-Epigallocatechin gallate suppresses proliferation of vascular smooth muscle cells induced by high glucose by inhibition of PKC and ERK1/2 signalings.
Topics: Camellia sinensis; Catechin; Cell Line; Cell Proliferation; Diabetic Cardiomyopathies; Down-Regulation; Glucose; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Plant Extracts; Protein Kinase C | 2011 |
Increases in blood pressure and heart rate induced by caffeine are inhibited by (-)-epigallocatechin-3-O-gallate: involvement of catecholamines.
Topics: Animals; Blood Pressure; Caffeine; Catechin; Epinephrine; Heart Rate; Male; Norepinephrine; Rats; Rats, Wistar | 2011 |
(-)-Epigallocatechin-3-gallate blocks 3T3-L1 adipose conversion by inhibition of cell proliferation and suppression of adipose phenotype expression.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Animals; Anticarcinogenic Agents; Azo Compounds; Blotting, Western; Catechin; CCAAT-Enhancer-Binding Protein-alpha; Cell Count; Cell Cycle; Cell Differentiation; Cell Proliferation; Coloring Agents; Dose-Response Relationship, Drug; Flow Cytometry; Mice; Phenotype; PPAR gamma; Real-Time Polymerase Chain Reaction; Signal Transduction | 2011 |
Green tea polyphenol epigallocatechin-3-gallate suppresses melanoma growth by inhibiting inflammasome and IL-1β secretion.
Topics: Animals; Antineoplastic Agents; Camellia sinensis; Catechin; Cell Line, Tumor; Cell Proliferation; Female; Humans; Inflammation; Interleukin-1beta; Melanoma; Mice; Mice, Nude; Polyphenols; Skin Neoplasms | 2011 |
Characteristics and kinetics of iron release from the ferritin under the EGCG reduction.
Topics: Animals; Ascorbic Acid; Catechin; Circular Dichroism; Elasmobranchii; Ferritins; Hydrogen-Ion Concentration; Iron; Kinetics; Liver | 2012 |
Comment on the special issue--green tea and cancer.
Topics: Catechin; Humans; Neoplasms; Tea | 2011 |
Therapeutic efficacy of topical epigallocatechin gallate in murine dry eye.
Topics: Animals; Antioxidants; Catechin; Chemokines; Cornea; Disease Models, Animal; Dry Eye Syndromes; Female; Fluorescein; Immunohistochemistry; Interleukin-1beta; Mice; Mice, Inbred C57BL; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor D | 2011 |
Proanthocyanidins modulate microRNA expression in human HepG2 cells.
Topics: Catechin; Computational Biology; Hep G2 Cells; Hepatocytes; Humans; Inflammation; Insulin; Lipid Metabolism; MicroRNAs; Oxidative Stress; Proanthocyanidins; Reproducibility of Results; Signal Transduction; Transcriptome | 2011 |
Epigallocatechin gallate, the major component of polyphenols in green tea, inhibits telomere attrition mediated cardiomyocyte apoptosis in cardiac hypertrophy.
Topics: Animals; Apoptosis; Cardiomegaly; Catechin; Male; Myocytes, Cardiac; Polyphenols; Rats; Rats, Sprague-Dawley; Tea; Telomere | 2013 |
Green tea catechins reduce invasive potential of human melanoma cells by targeting COX-2, PGE2 receptors and epithelial-to-mesenchymal transition.
Topics: Catechin; Celecoxib; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Humans; Melanoma; Neoplasm Invasiveness; NF-kappa B; Pyrazoles; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sulfonamides; Tea; Tetradecanoylphorbol Acetate; Transcription Factor RelA | 2011 |
Neuroprotective effect of combination therapy of glatiramer acetate and epigallocatechin-3-gallate in neuroinflammation.
Topics: Animals; Axons; Catechin; Cell Count; Cell Death; Central Nervous System; Drug Therapy, Combination; Encephalomyelitis, Autoimmune, Experimental; Female; Glatiramer Acetate; Inflammation; Mice; Neuroprotective Agents; Peptides | 2011 |
670 nm laser light and EGCG complementarily reduce amyloid-β aggregates in human neuroblastoma cells: basis for treatment of Alzheimer's disease?
Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid; Antineoplastic Agents; Brain Neoplasms; Catechin; Humans; Low-Level Light Therapy; Microscopy, Fluorescence; Neuroblastoma; Tumor Cells, Cultured; Ultrasonography | 2012 |
AFM study of the differential inhibitory effects of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) against Gram-positive and Gram-negative bacteria.
Topics: Camellia sinensis; Catechin; Escherichia coli O157; Hydrogen Peroxide; Microbial Viability; Microscopy, Atomic Force; Oxidative Stress; Plant Extracts; Staphylococcus aureus | 2012 |
Effects of (-)-epigallocatechin-3-O-gallate on expression of gluconeogenesis-related genes in the mouse duodenum.
Topics: Acetylcysteine; Animals; Antioxidants; Catechin; Cell Line, Tumor; Dose-Response Relationship, Drug; Duodenum; Gene Expression Regulation; Gluconeogenesis; Humans; Mice | 2011 |
(-)-Epigallocatechin-3-gallate protects against neuronal cell death and improves cerebral function after traumatic brain injury in rats.
Topics: Animals; Apoptosis; Brain Injuries; Catechin; Cerebral Cortex; Cognition Disorders; DNA, Single-Stranded; Lipid Peroxidation; Male; Malondialdehyde; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Tea | 2011 |
Neuroprotection of green tea catechins on surgical menopause-induced overactive bladder in a rat model.
Topics: Animals; Catechin; Disease Models, Animal; Female; Menopause; Neuroprotective Agents; Ovariectomy; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Tea; Urinary Bladder, Overactive | 2012 |
Green tea catechin intervention of reactive oxygen species-mediated ERK pathway activation and chronically induced breast cell carcinogenesis.
Topics: Benzo(a)pyrene; Breast Neoplasms; Catechin; Cell Proliferation; Cells, Cultured; DNA Damage; Extracellular Signal-Regulated MAP Kinases; Female; Humans; MAP Kinase Signaling System; Nitrosamines; Reactive Oxygen Species; Tea | 2012 |
The effect of green tea polyphenols on macrophage migration inhibitory factor-associated steroid resistance.
Topics: Anti-Inflammatory Agents; Camellia sinensis; Catechin; Chemokines; Cytokines; Dermatitis; Dexamethasone; Drug Resistance; Glucocorticoids; Humans; Keratinocytes; Macrophage Migration-Inhibitory Factors; Plant Extracts; Polyphenols; Recombinant Proteins; RNA, Messenger; Up-Regulation | 2012 |
Black tea theaflavins inhibit formation of toxic amyloid-β and α-synuclein fibrils.
Topics: alpha-Synuclein; Amyloid; Amyloid beta-Peptides; Animals; Antioxidants; Biflavonoids; Binding Sites; Camellia sinensis; Catechin; Cell Line, Tumor; Congo Red; Drug Evaluation, Preclinical; Fluorescence; Hydrophobic and Hydrophilic Interactions; Plaque, Amyloid; Protein Denaturation; Rats | 2011 |
Epigallocatechin-3-gallate ameliorates experimental autoimmune encephalomyelitis by altering balance among CD4+ T-cell subsets.
Topics: Animals; Catechin; CD4-Positive T-Lymphocytes; Cell Proliferation; Cytokines; Demyelinating Diseases; Dietary Supplements; Down-Regulation; Encephalomyelitis, Autoimmune, Experimental; Female; Mice; Mice, Inbred C57BL; Monocytes; Multiple Sclerosis; Myelin Proteins; Myelin-Oligodendrocyte Glycoprotein; Neuritis; Neuroprotective Agents; Nuclear Receptor Subfamily 1, Group F, Member 3; Random Allocation; T-Box Domain Proteins; T-Lymphocyte Subsets | 2012 |
Pro-apoptotic and anti-inflammatory properties of the green tea constituent epigallocatechin gallate increase photodynamic therapy responsiveness.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Catechin; Cell Line, Tumor; Dihematoporphyrin Ether; Dinoprostone; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum Chaperone BiP; Female; Heat-Shock Proteins; Inflammation; Mammary Neoplasms, Experimental; Matrix Metalloproteinases, Secreted; Mice; Mice, Inbred C3H; Photochemotherapy; Photosensitizing Agents; Unfolded Protein Response; Vascular Endothelial Growth Factors | 2011 |
Shattering the underpinnings of neoplastic architecture in LNCap: synergistic potential of nutraceuticals in dampening PDGFR/EGFR signaling and cellular proliferation.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Catechin; Cell Line, Tumor; Cell Proliferation; Curcumin; Drug Synergism; ErbB Receptors; Humans; Isothiocyanates; Male; Phosphorylation; Prostatic Neoplasms; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Sulfoxides; Thiocyanates | 2011 |
(-)-Epigallocatechin-3-gallate: a novel storage medium for avulsed teeth.
Topics: Animals; Catechin; Cell Survival; Cells, Cultured; Humans; Isotonic Solutions; Milk; Organ Preservation Solutions; Periodontal Ligament; Tooth Avulsion | 2012 |
EGCG ameliorates the suppression of long-term potentiation induced by ischemia at the Schaffer collateral-CA1 synapse in the rat.
Topics: Amino Acids; Animals; Brain Infarction; Brain Ischemia; CA1 Region, Hippocampal; Catechin; Cell Shape; Cerebral Cortex; Extracellular Space; Glucose; Infarction, Middle Cerebral Artery; Long-Term Potentiation; Male; Neurons; Oxygen; Rats; Rats, Sprague-Dawley; Synapses | 2012 |
Epigallocatechin-3-gallate (EGCG) protects against chromate-induced toxicity in vitro.
Topics: Antioxidants; Apoptosis; Bronchi; Carcinogens, Environmental; Catechin; Chromium; Dose-Response Relationship, Drug; Epithelial Cells; Free Radical Scavengers; Gene Expression Regulation; Humans; Microscopy, Fluorescence; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Reactive Oxygen Species | 2012 |
EGCG inhibits the invasion of highly invasive CL1-5 lung cancer cells through suppressing MMP-2 expression via JNK signaling and induces G2/M arrest.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Line, Tumor; G2 Phase Cell Cycle Checkpoints; Gene Expression; Humans; Lung Neoplasms; M Phase Cell Cycle Checkpoints; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Tea | 2011 |
(-)-Epigallocatechin-3-gallate enhances the expression of an insulin-inducible transcription factor gene via a phosphoinositide 3-kinase/atypical protein kinase C lambda pathway.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Catechin; Cell Line, Tumor; Enzyme Inhibitors; Gene Expression; Insulin; Isoenzymes; Liver Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Rats; RNA, Messenger; Signal Transduction | 2011 |
Lipid rafts mediate epigallocatechin-3-gallate- and green tea extract-dependent viability of human colon adenocarcinoma COLO 205 cells; clusterin affects lipid rafts-associated signaling pathways.
Topics: beta Catenin; Camellia sinensis; Catechin; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Cell Survival; Clusterin; Dose-Response Relationship, Drug; Humans; MAP Kinase Signaling System; Membrane Microdomains; Plant Extracts; Time Factors | 2011 |
Epigallocatechin gallate suppresses peritoneal fibrosis in mice.
Topics: Animals; Catechin; Chemokine CCL2; Dialysis Solutions; Inflammation; Male; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; NF-kappa B; Peritoneal Fibrosis; Peritoneum; Platelet Endothelial Cell Adhesion Molecule-1; Pyruvaldehyde; Reactive Oxygen Species; Vascular Endothelial Growth Factor A | 2012 |
Epigallocatechin-3-gallate inhibits proliferation and migration of human colon cancer SW620 cells in vitro.
Topics: Anticarcinogenic Agents; Caspase 7; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colonic Neoplasms; Cytoskeleton; Extracellular Signal-Regulated MAP Kinases; Factor VIIa; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 9; NF-kappa B; Oligopeptides; Receptor, PAR-2; Signal Transduction | 2012 |
Binding with nucleic acids or glycosaminoglycans converts soluble protein oligomers to amyloid.
Topics: Amyloidogenic Proteins; Carbodiimides; Catechin; Cell Death; Cross-Linking Reagents; DNA; Glycosaminoglycans; HEK293 Cells; Humans; Jurkat Cells; Methylamines; Protein Multimerization; Protein Stability; Protein Structure, Quaternary; RNA; Solubility | 2012 |
(-)-Epigallocatechin-3-gallate is a new inhibitor of hepatitis C virus entry.
Topics: Animals; Antiviral Agents; Catechin; Cattle; Cell Line; Chlorocebus aethiops; Dose-Response Relationship, Drug; Hepacivirus; Hepatitis C; Hepatocytes; Humans; Kidney; Lipid Metabolism; Models, Animal; Plant Extracts; Tea; Vero Cells; Virus Internalization; Virus Replication | 2012 |
Structural perspective on the direct inhibition mechanism of EGCG on mammalian histidine decarboxylase and DOPA decarboxylase.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Catechin; Dopa Decarboxylase; Histidine Decarboxylase; Mammals; Molecular Dynamics Simulation; Tea | 2012 |
Synthesis and antiviral activity of substituted quercetins.
Topics: Animals; Antiviral Agents; Catechin; Chemistry, Pharmaceutical; Drug Design; Humans; Inhibitory Concentration 50; Models, Chemical; Molecular Conformation; Orthomyxoviridae; Quercetin; Swine; Virus Diseases | 2012 |
Broad inhibition of plasmodium falciparum cytoadherence by (+)-epigallocatechin gallate.
Topics: Antimalarials; Catechin; Cell Adhesion; Child; Child, Preschool; Erythrocytes; Humans; Intercellular Adhesion Molecule-1; Malaria, Falciparum; Microscopy; Plasmodium falciparum; Protein Binding | 2011 |
Epigallocatechin gallate induces expression of heme oxygenase-1 in endothelial cells via p38 MAPK and Nrf-2 that suppresses proinflammatory actions of TNF-α.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidant Response Elements; Aorta; Catechin; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Enzyme Induction; Heme Oxygenase-1; Humans; Liver; MAP Kinase Signaling System; Membrane Proteins; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; RNA Interference; RNA, Messenger; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2012 |
The interaction between tea polyphenols and rice starch during gelatinization.
Topics: Catechin; Chemical Phenomena; Food Additives; Gels; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Oryza; Phase Transition; Polyphenols; Seeds; Spectroscopy, Fourier Transform Infrared; Starch; Tea; Viscosity | 2011 |
Label free inhibitor screening of hepatitis C virus (HCV) NS5B viral protein using RNA oligonucleotide.
Topics: Antiviral Agents; Aptamers, Nucleotide; Biotin; Catechin; Computer Systems; Hepacivirus; Hepatitis C; Humans; Streptavidin; Viral Nonstructural Proteins | 2011 |
The effects of oxaloacetate on hydrogen peroxide generation from ascorbate and epigallocatechin gallate in cell culture media: potential for altering cell metabolism.
Topics: Ascorbic Acid; Catechin; Cells; Cells, Cultured; Culture Media; Hydrogen Peroxide; Oxaloacetic Acid | 2012 |
Tea catechin epigallocatechin gallate inhibits Streptococcus mutans biofilm formation by suppressing gtf genes.
Topics: Analysis of Variance; Anti-Infective Agents; Bacterial Adhesion; Bacterial Proteins; Biofilms; Catechin; Dose-Response Relationship, Drug; Gene Expression Regulation, Bacterial; Glucosyltransferases; Real-Time Polymerase Chain Reaction; Streptococcus mutans; Tea; Virulence Factors | 2012 |
Effects of intrathecal epigallocatechin gallate, an inhibitor of Toll-like receptor 4, on chronic neuropathic pain in rats.
Topics: Animals; Catechin; Chronic Disease; Constriction; Gene Expression Regulation; HMGB1 Protein; Injections, Spinal; Interleukin-10; Interleukin-1beta; Male; Neuralgia; NF-kappa B; Pain Threshold; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sciatic Nerve; Spinal Cord; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2012 |
Adrenomedullin interacts with VEGF in endometrial cancer and has varied modulation in tumours of different grades.
Topics: Adenocarcinoma; Adrenomedullin; Biomarkers, Tumor; Case-Control Studies; Catechin; Cell Line, Tumor; Cobalt; Endometrial Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Grading; Resveratrol; RNA, Messenger; Stilbenes; Up-Regulation; Vascular Endothelial Growth Factor A | 2012 |
A tea catechin, epigallocatechin-3-gallate, is a unique modulator of the farnesoid X receptor.
Topics: Animals; Catechin; Cells, Cultured; Chenodeoxycholic Acid; Dose-Response Relationship, Drug; Gene Expression Regulation; Hep G2 Cells; Humans; Inhibitory Concentration 50; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nuclear Receptor Coactivator 2; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Tea | 2012 |
Tea polyphenols inhibit rat osteoclast formation and differentiation.
Topics: Animals; Biflavonoids; Camellia sinensis; Catechin; Cell Differentiation; Cells, Cultured; Gallic Acid; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Osteoclasts; Rats; Rats, Wistar; RNA, Messenger | 2012 |
Suppression of free fatty acid-induced insulin resistance by phytopolyphenols in C2C12 mouse skeletal muscle cells.
Topics: Animals; Catechin; Cell Line; Curcumin; Enzyme Activation; Fatty Acids, Nonesterified; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Muscle, Skeletal; Palmitic Acid; Phosphorylation; Polyphenols; Protein Kinase C; Serine; Signal Transduction; Tetradecanoylphorbol Acetate | 2012 |
NMR characterization of monomeric and oligomeric conformations of human calcitonin and its interaction with EGCG.
Topics: Amino Acid Sequence; Calcitonin; Catechin; Humans; Microscopy, Electron; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Structure, Secondary | 2012 |
Assessment of multicomponent hydrogel scaffolds of poly(acrylic acid-2-hydroxy ethyl methacrylate)/gelatin for tissue engineering applications.
Topics: Acrylic Resins; Animals; Antioxidants; Catechin; Cell Line; Cell Survival; Delayed-Action Preparations; Fibroblasts; Gelatin; Hydrogel, Polyethylene Glycol Dimethacrylate; Methacrylates; Mice; Tissue Engineering; Tissue Scaffolds | 2013 |
(-)-Epigallocatechin-3-gallate increases the number of neural stem cells around the damaged area after rat traumatic brain injury.
Topics: Animals; Brain Injuries; Catechin; Cell Proliferation; Immunohistochemistry; Lipid Peroxidation; Male; Neural Stem Cells; Neuroprotective Agents; Rats; Rats, Wistar | 2012 |
[Mechanism of interaction between risperidone and tea catechin (2) influence of presence of galloyl group in catechin on insoluble complex formation with risperidone].
Topics: Antipsychotic Agents; Catechin; Dose-Response Relationship, Drug; Drug Interactions; Drug Stability; Hydrogen Bonding; Macromolecular Substances; Models, Molecular; Risperidone; Solubility; Tea | 2012 |
Differential protective effects of quercetin, resveratrol, rutin and epigallocatechin gallate against mitochondrial dysfunction induced by indomethacin in Caco-2 cells.
Topics: Adenosine Triphosphate; Caco-2 Cells; Catechin; Drug Interactions; Electron Transport Complex I; Gastrointestinal Diseases; Humans; Indomethacin; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Diseases; Quercetin; Resveratrol; Rutin; Stilbenes; Superoxides | 2012 |
Polyphenol content of plasma and litter after the oral administration of green tea and tea polyphenols in chickens.
Topics: Animal Nutritional Physiological Phenomena; Animals; Catechin; Chickens; Chromatography, Liquid; Manure; Polyphenols; Tandem Mass Spectrometry; Tea | 2012 |
The green tea polyphenol (2)-epigallocatechin-3-gallate (EGCG) is not a β-secretase inhibitor.
Topics: Amyloid Precursor Protein Secretases; Animals; Biological Assay; Catechin; CHO Cells; Cricetinae; Enzyme Activation; Enzyme Inhibitors; False Positive Reactions; Fluorescent Dyes; Inhibitory Concentration 50; Molecular Structure | 2012 |
EGCG debilitates the persistence of EBV latency by reducing the DNA binding potency of nuclear antigen 1.
Topics: Catechin; DNA; Epstein-Barr Virus Nuclear Antigens; Herpesvirus 4, Human; Humans; Replication Origin; Virus Latency; Virus Replication | 2012 |
Adsorption characteristics of (-)-epigallocatechin gallate and caffeine in the extract of waste tea on macroporous adsorption resins functionalized with chloromethyl, amino, and phenylamino groups.
Topics: Adsorption; Caffeine; Catechin; Chemical Phenomena; Indicators and Reagents; Kinetics; Spectroscopy, Fourier Transform Infrared; Tea; Thermodynamics | 2012 |
Role of neuronal nitric oxide synthase in the antiallodynic effects of intrathecal EGCG in a neuropathic pain rat model.
Topics: Animals; Arginine; Catechin; Disease Models, Animal; Extremities; Hyperalgesia; Injections, Spinal; Ligation; Male; Neuralgia; Nitric Oxide; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Nerves | 2012 |
Suppression of esophageal cancer cell growth using curcumin, (-)-epigallocatechin-3-gallate and lovastatin.
Topics: Animals; Anticarcinogenic Agents; Anticholesteremic Agents; Catechin; Cell Line, Tumor; Curcumin; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Esophageal Neoplasms; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Humans; JNK Mitogen-Activated Protein Kinases; Lovastatin; Mice; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous | 2012 |
Epigallocatechin-3-gallate as a potential therapeutic drug for TTR-related amyloidosis: "in vivo" evidence from FAP mice models.
Topics: Amyloid; Amyloid Neuropathies, Familial; Animals; Biomarkers; Catechin; Colon; Disease Models, Animal; Endoplasmic Reticulum Stress; Gastric Mucosa; Humans; Mice; Mice, Transgenic; Peripheral Nervous System; Prealbumin; Stomach | 2012 |
Green tea polyphenol EGCG induces lipid-raft clustering and apoptotic cell death by activating protein kinase Cδ and acid sphingomyelinase through a 67 kDa laminin receptor in multiple myeloma cells.
Topics: Animals; Apoptosis; Caspase 3; Catechin; Cell Line, Tumor; Enzyme Activation; Humans; Membrane Microdomains; Mice; Molecular Weight; Multiple Myeloma; Protein Kinase C-delta; Receptors, Laminin; Sphingomyelin Phosphodiesterase; Tea | 2012 |
Perioperative polyphenon E- and siliphos-inhibited colorectal tumor growth and metastases without impairment of gastric or abdominal wound healing in mouse models.
Topics: Abdomen; Analysis of Variance; Animals; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Collagen; Colorectal Neoplasms; Drug Combinations; Female; Laparotomy; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neoplasm Transplantation; Perioperative Period; Pneumoperitoneum, Artificial; Pressure; Random Allocation; Silybin; Silymarin; Stomach; Surgical Wound Dehiscence; Wound Healing | 2012 |
Epigallocatechin-3-gallate and penta-O-galloyl-β-D-glucose inhibit protein phosphatase-1.
Topics: Catechin; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; HeLa Cells; Humans; Hydrolyzable Tannins; Isoenzymes; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Protein Binding; Protein Phosphatase 1; Protein Phosphatase 2; Protein Structure, Tertiary; Surface Plasmon Resonance; Tea | 2013 |
Zinc ion enhances GABA tea-mediated oxidative DNA damage.
Topics: Antioxidants; Bacteriophage phi X 174; Catalase; Catechin; Comet Assay; DNA Damage; DNA, Viral; gamma-Aminobutyric Acid; Glutathione; Humans; Hydrogen Peroxide; Lymphocytes; Oxidants; Oxidation-Reduction; Potassium Iodide; Tea; Zinc | 2012 |
Nanochemoprevention by encapsulation of (-)-epigallocatechin-3-gallate with bioactive peptides/chitosan nanoparticles for enhancement of its bioavailability.
Topics: Biological Availability; Caco-2 Cells; Capsules; Catechin; Chemoprevention; Chitosan; Drug Carriers; Humans; Nanoparticles; Peptide Fragments | 2012 |
Anti-cancer activities of tea epigallocatechin-3-gallate in breast cancer patients under radiotherapy.
Topics: Administration, Oral; Adult; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Chemotherapy, Adjuvant; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Hepatocyte Growth Factor; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Neoplasm Invasiveness; NF-kappa B; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-met; Tea; Vascular Endothelial Growth Factor A | 2012 |
Low-dose docetaxel combined with (-)-epigallocatechin-3-gallate inhibits angiogenesis and tumor growth in nude mice with gastric cancer xenografts.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Catechin; Cell Proliferation; Docetaxel; Dose-Response Relationship, Drug; Drug Synergism; Humans; Immunoenzyme Techniques; Mice; Mice, Inbred BALB C; Mice, Nude; Microvessels; Neovascularization, Pathologic; Platelet Endothelial Cell Adhesion Molecule-1; Stomach Neoplasms; Taxoids; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2012 |
Higher cell stiffness indicating lower metastatic potential in B16 melanoma cell variants and in (-)-epigallocatechin gallate-treated cells.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Movement; Elastic Modulus; Elasticity; Melanoma, Experimental; Mice; Microscopy, Atomic Force; Skin Neoplasms | 2012 |
Effects of (-)-epigallocatechin gallate on the motility and penetrability of frozen-thawed boar spermatozoa incubated in the fertilization medium.
Topics: Animals; Catechin; Cryopreservation; Dose-Response Relationship, Drug; Female; Fertilization in Vitro; Male; Semen Preservation; Sperm Motility; Sperm-Ovum Interactions; Spermatozoa; Swine | 2012 |
Structural properties of EGCG-induced, nontoxic Alzheimer's disease Aβ oligomers.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Catechin; Humans; Magnetic Resonance Spectroscopy; Neuroprotective Agents; Protein Conformation; Protein Denaturation; Protein Multimerization | 2012 |
Intervention of human breast cell carcinogenesis chronically induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Topics: Base Sequence; Breast Neoplasms; Carcinogens; Catechin; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA Primers; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction | 2012 |
(-)-Epigallocatechin gallate induces Fas/CD95-mediated apoptosis through inhibiting constitutive and IL-6-induced JAK/STAT3 signaling in head and neck squamous cell carcinoma cells.
Topics: Apoptosis; Carcinoma, Squamous Cell; Catechin; Down-Regulation; Fas Ligand Protein; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Interleukin-6; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; STAT3 Transcription Factor | 2012 |
Antioxidative properties of functional polyphenols and their metabolites assessed by an ORAC assay.
Topics: Antioxidants; Catechin; Chlorogenic Acid; Hydrolyzable Tannins; Polyphenols; Reactive Oxygen Species | 2012 |
Endothelium/nitric oxide mechanism mediates vasorelaxation and counteracts vasoconstriction induced by low concentration of flavanols.
Topics: Animals; Aorta, Thoracic; Catechin; Endothelium, Vascular; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Phenylephrine; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Vasoconstriction; Vasodilation; Vasodilator Agents | 2013 |
Epigallocatechin-3-gallate inhibits expression of receptors for T cell regulatory cytokines and their downstream signaling in mouse CD4+ T cells.
Topics: Animals; Catechin; CD4-Positive T-Lymphocytes; Cell Proliferation; Down-Regulation; Female; Interleukin-15; Interleukin-2; Interleukin-7; Mice; Mice, Inbred C57BL; Receptors, Cytokine; Receptors, Interleukin-15; Receptors, Interleukin-2; Receptors, Interleukin-7; Signal Transduction | 2012 |
Green tea polyphenol epigallocatechin-3-gallate shows therapeutic antioxidative effects in a murine model of colitis.
Topics: Alkaloids; Analysis of Variance; Animals; Antioxidants; Benzodioxoles; Catechin; Colitis; Dextran Sulfate; Female; Glutathione Peroxidase; HT29 Cells; Humans; Interleukin-8; Malondialdehyde; Mice; Mice, Inbred C57BL; Oxidative Stress; Peroxidase; Piperidines; Polyunsaturated Alkamides; Reactive Oxygen Species; Superoxide Dismutase; Weight Loss | 2012 |
Complementary therapies, herbs, and other OTC agents: Green tea (Camellia sinensis).
Topics: Anticarcinogenic Agents; Camellia sinensis; Catechin; Herb-Drug Interactions; Neoplasms; Phytotherapy; Plant Extracts; Plant Leaves | 2011 |
The role of peroxiredoxin V in (-)-epigallocatechin 3-gallate-induced multiple myeloma cell death.
Topics: Acetylcysteine; Apoptosis; Catechin; Cell Line, Tumor; Cell Survival; Extracellular Signal-Regulated MAP Kinases; Humans; JNK Mitogen-Activated Protein Kinases; Multiple Myeloma; p38 Mitogen-Activated Protein Kinases; Peroxiredoxins; Phosphorylation; Plasma Cells; Reactive Oxygen Species; Signal Transduction; Syndecan-1 | 2011 |
Attenuation of murine graft-versus-host disease by a tea polyphenol.
Topics: Animals; Catechin; CD28 Antigens; CD3 Complex; CD4 Antigens; Cell Proliferation; Female; Graft Survival; Graft vs Host Disease; Immunocompromised Host; Interferon-gamma; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mitogens; Polyphenols; Spleen; Tea | 2012 |
Quantitative evaluation of the beneficial effects in the mdx mouse of epigallocatechin gallate, an antioxidant polyphenol from green tea.
Topics: Animals; Antioxidants; Body Weight; Catechin; Disease Models, Animal; Eating; Female; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscular Dystrophy, Duchenne; Oxidative Stress; Polyphenols; Tea | 2012 |
Formation of low-dimensional crystalline nucleus region during insulin amyloidogenesis process.
Topics: Amyloid; Catechin; Circular Dichroism; Crystallization; Humans; Insulin; Microscopy, Atomic Force; Protein Conformation; Spectrometry, Fluorescence | 2012 |
Preparative separation and purification of epigallocatechin gallate from green tea extracts using a silica adsorbent containing β-cyclodextrin.
Topics: Adsorption; beta-Cyclodextrins; Caffeine; Catechin; Plant Extracts; Silicon Dioxide; Tea | 2012 |
Two-photon excitation with pico-second fluorescence lifetime imaging to detect nuclear association of flavanols.
Topics: Catechin; Flavonols; Microscopy, Fluorescence, Multiphoton; Onions; Spectrometry, Fluorescence; Taxus | 2012 |
Chitosan-based luminescent/magnetic hybrid nanogels for insulin delivery, cell imaging, and antidiabetic research of dietary supplements.
Topics: Catechin; Cell Line; Cell Survival; Chitosan; Dietary Supplements; Drug Delivery Systems; Ferric Compounds; Hepatocytes; Humans; Hypoglycemic Agents; Insulin; Luminescence; Magnetics; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanoparticles; Particle Size; Quantum Dots; Receptor, Insulin; Spectroscopy, Fourier Transform Infrared; Xanthones | 2012 |
EGCG enhances the therapeutic potential of gemcitabine and CP690550 by inhibiting STAT3 signaling pathway in human pancreatic cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Catechin; Cell Line, Tumor; Cell Movement; Cell Survival; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; Pancreatic Neoplasms; Piperidines; Pyrimidines; Pyrroles; Signal Transduction; STAT3 Transcription Factor | 2012 |
Epigallocatechin-3-gallate potentiates curcumin's ability to suppress uterine leiomyosarcoma cell growth and induce apoptosis.
Topics: Apoptosis; Biological Availability; Catechin; Cell Line, Tumor; Cell Proliferation; Curcumin; Drug Synergism; Female; Humans; Leiomyosarcoma; Oncogene Protein v-akt; Receptors, Laminin; Ribosomal Protein S6 Kinases; Signal Transduction; TOR Serine-Threonine Kinases; Uterine Neoplasms | 2013 |
Flavonoid-mediated inhibition of SARS coronavirus 3C-like protease expressed in Pichia pastoris.
Topics: Catechin; Coronavirus 3C Proteases; Cysteine Endopeptidases; Flavonoids; Gene Expression; Hydrolysis; Inhibitory Concentration 50; Kinetics; Molecular Weight; Pichia; Protease Inhibitors; Recombinant Proteins; Severe acute respiratory syndrome-related coronavirus; Viral Proteins | 2012 |
Factors influencing the antioxidant and pro-oxidant activity of polyphenols in oil-in-water emulsions.
Topics: Antioxidants; Catechin; Emulsions; Hydrogen-Ion Concentration; Models, Chemical; Oils; Oxidants; Oxidation-Reduction; Polyphenols; Water | 2012 |
Site specific interaction of the polyphenol EGCG with the SEVI amyloid precursor peptide PAP(248-286).
Topics: Acid Phosphatase; Amino Acid Sequence; Catechin; HIV Infections; Humans; Hydrogen-Ion Concentration; Kinetics; Microscopy, Fluorescence; Molecular Sequence Data; Protein Binding; Protein Multimerization; Protein Tyrosine Phosphatases; Serum Amyloid A Protein | 2012 |
Effects of a catechin-free fraction derived from green tea on gene expression of enzymes related to lipid metabolism in the mouse liver.
Topics: Animals; Arteriosclerosis; Blood Glucose; Catechin; Cholesterol; Down-Regulation; Glucose-6-Phosphatase; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred BALB C; Obesity; Phosphoenolpyruvate Carboxykinase (ATP); Plant Extracts; Plant Leaves; Real-Time Polymerase Chain Reaction; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Tea; Triglycerides | 2012 |
Interaction of tea polyphenols and food constituents with model gut epithelia: the protective role of the mucus gel layer.
Topics: Caseins; Catechin; Cell Survival; Cytoprotection; Drug Interactions; Food; HT29 Cells; Humans; Intestinal Mucosa; Kinetics; Mucins; Mucus; Polyphenols; Polysaccharides; Tea | 2012 |
Impact of epigallo catechin-3-gallate on acetylcholine-acetylcholine esterase cycle in aged rat brain.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Behavior, Animal; Brain; Catechin; Kinetics; Male; Rats; Rats, Wistar | 2012 |
Inhibitory effects of epigallocatechin-3-gallate on cell proliferation and the expression of HIF-1α and P-gp in the human pancreatic carcinoma cell line PANC-1.
Topics: Antineoplastic Agents; Antioxidants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma; Catechin; Cell Line, Tumor; Cell Proliferation; Gene Expression; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Pancreatic Neoplasms; RNA, Messenger; Transcription, Genetic | 2012 |
Epigallocatechin-3-gallate prevents TNF-α-induced NF-κB activation thereby upregulating ABCA1 via the Nrf2/Keap1 pathway in macrophage foam cells.
Topics: Anti-Inflammatory Agents; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Catechin; Cell Line; Cholesterol; Foam Cells; Humans; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; NF-kappa B; Signal Transduction; Tumor Necrosis Factor-alpha; Up-Regulation | 2012 |
Biochemical characterization of novel lignans isolated from the wood of Taxus yunnanensis as effective stimulators for glycogen synthase kinase-3β and the phosphorylation of basic brain proteins by the kinase in vitro.
Topics: Animals; Brain; Catechin; Cattle; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Intercellular Signaling Peptides and Proteins; Lignans; Myelin Basic Protein; Nerve Tissue Proteins; Phosphorylation; Plant Extracts; Rats; Recombinant Proteins; tau Proteins; Taxus; Wood | 2012 |
Preparation, evaluation and characterization of quercetin-molecularly imprinted polymer for preconcentration and clean-up of catechins.
Topics: Adsorption; Catechin; Chromatography, High Pressure Liquid; Hydrogen Bonding; Kinetics; Molecular Imprinting; Polymers; Quercetin; Solid Phase Extraction | 2012 |
Analysis of in vitro chemoprevention of genotoxic damage by phytochemicals, as single agents or as combinations.
Topics: Anthocyanins; Antimutagenic Agents; Antioxidants; Catechin; Chlorogenic Acid; Diet; DNA Damage; HL-60 Cells; Humans; Micronucleus Tests; Mitomycin; Phytotherapy; Plants; Reactive Oxygen Species; Resveratrol; Stilbenes | 2012 |
A portable electrochemical sensor for caffeine and (-)epigallocatechin gallate based on molecularly imprinted poly(ethylene-co-vinyl alcohol) recognition element.
Topics: Caffeine; Catechin; Electrochemistry; Polyvinyls | 2011 |
The green tea polyphenol (-)-epigallocatechin gallate precipitates salivary proteins including alpha-amylase: biochemical implications for oral health.
Topics: Adult; Aggregatibacter actinomycetemcomitans; alpha-Amylases; Anti-Bacterial Agents; Catechin; Cystatins; Dental Caries; Dietary Carbohydrates; Female; Humans; Male; Middle Aged; Protein Binding; Proteome; Saliva; Salivary Proteins and Peptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tea; Young Adult | 2012 |
Preservation of (-)-epigallocatechin-3-gallate antioxidant properties loaded in heat treated β-lactoglobulin nanoparticles.
Topics: Antioxidants; Catechin; Drug Stability; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Lactoglobulins; Nanoparticles; Protein Structure, Secondary | 2012 |
Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently suppresses dextran sulfate sodium-induced colitis and colon tumorigenesis in mice.
Topics: Acetates; Acetylation; Animals; Catechin; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Down-Regulation; Gene Expression; Humans; Male; Mice; Mice, Inbred ICR; Premedication; Signal Transduction | 2012 |
Analysis of the inhibition and remodeling of islet amyloid polypeptide amyloid fibers by flavanols.
Topics: Amino Acid Sequence; Catechin; Humans; Islet Amyloid Polypeptide; Microscopy, Electron, Transmission; Molecular Sequence Data; Solubility; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2012 |
A new strategy for detection and development of tractable telomerase inhibitors.
Topics: Aminobenzoates; Benzamides; Catechin; Enzyme Inhibitors; HeLa Cells; Humans; Inhibitory Concentration 50; Kinetics; Naphthalenes; Porphyrins; Quinones; Telomerase; Tetrahymena | 2012 |
EGCG blocks TGFβ1-induced CCN2 by suppressing JNK and p38 in buccal fibroblasts.
Topics: Anthracenes; Benzamides; Catechin; Cell Line; Cells, Cultured; Connective Tissue Growth Factor; Dinoprostone; Dioxoles; Dose-Response Relationship, Drug; Fibroblasts; Flavonoids; Humans; Imidazoles; Lung; MAP Kinase Kinase 4; Mouth Mucosa; Oral Submucous Fibrosis; p38 Mitogen-Activated Protein Kinases; Protease Inhibitors; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2013 |
A profile of bioactive compounds of Rumex vesicarius L.
Topics: 1-Butanol; alpha-Tocopherol; Antioxidants; Apigenin; beta Carotene; Catechin; Chromatography, High Pressure Liquid; Egypt; Food Analysis; Fruit; Glucosides; Herbal Medicine; Luteolin; Phenols; Plant Extracts; Plant Leaves; Plant Roots; Quercetin; Rumex; Silymarin; Tandem Mass Spectrometry | 2011 |
Epigallocatechin-3-gallate inhibits apoptosis and protects testicular seminiferous tubules from ischemia/reperfusion-induced inflammation.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Catechin; Enzyme-Linked Immunosorbent Assay; Interleukin-1beta; Interleukin-6; Male; Nitric Oxide Synthase Type II; Orchitis; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Receptors, CCR2; Reperfusion Injury; RNA, Messenger; Seminiferous Tubules; Spermatic Cord Torsion; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53 | 2012 |
DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity.
Topics: Azacitidine; Caspase 3; Catechin; Cell Line, Tumor; Cytidine; Decitabine; Disulfides; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Breaks, Double-Stranded; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA Repair; Enzyme Induction; Gene Expression Regulation, Neoplastic; Glioblastoma; Histones; Humans; Hydralazine; Inhibitory Concentration 50; Lung Neoplasms; Neoplasm Proteins; Radiation-Sensitizing Agents; Tumor Stem Cell Assay; Tyrosine | 2012 |
A new norisoprenoid and other compounds from Fuzhuan brick tea.
Topics: alpha-Linolenic Acid; Anti-Bacterial Agents; Apigenin; Camellia sinensis; Catechin; Enteropathogenic Escherichia coli; Gallic Acid; Molecular Structure; Norisoprenoids | 2012 |
Perioperative polyphenon E, a green tea extract, does not affect the wound complication rate in mice after sham laparotomy yet has an inhibitory effect on wound healing.
Topics: Abdominal Wall; Administration, Oral; Animals; Biomechanical Phenomena; Body Weight; Catechin; Cell Proliferation; Chi-Square Distribution; Collagen; Female; Fibroblasts; Laparotomy; Mice; Mice, Inbred BALB C; Postoperative Period; Pressure; Wound Healing | 2012 |
(-)-Epigallocathechin-3-gallate, an AMPK activator, decreases ovariectomy-induced bone loss by suppression of bone resorption.
Topics: AMP-Activated Protein Kinases; Animals; Body Weight; Bone Density; Bone Resorption; Catechin; Enzyme Activators; Female; Mice; Ovariectomy; Protease Inhibitors | 2012 |
Quercetin increased bioavailability and decreased methylation of green tea polyphenols in vitro and in vivo.
Topics: Animals; Biological Availability; Catechin; Catechol O-Methyltransferase; Cell Line, Tumor; Down-Regulation; Humans; Male; Methylation; Mice; Mice, SCID; Neoplasms; Polyphenols; Quercetin; Tea; Up-Regulation | 2012 |
Down-regulation of glucose-regulated protein (GRP) 78 potentiates cytotoxic effect of celecoxib in human urothelial carcinoma cells.
Topics: Apoptosis; Catechin; Celecoxib; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2 Inhibitors; Down-Regulation; Drug Synergism; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; G1 Phase Cell Cycle Checkpoints; Heat-Shock Proteins; Humans; Indoles; Leupeptins; Pyrazoles; RNA, Small Interfering; Stress, Physiological; Sulfonamides; Unfolded Protein Response; Urinary Bladder Neoplasms | 2012 |
Quercetin increased the antiproliferative activity of green tea polyphenol (-)-epigallocatechin gallate in prostate cancer cells.
Topics: Androgens; Anticarcinogenic Agents; Catechin; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Humans; Male; Methylation; Prostatic Neoplasms; Quercetin; Tea | 2012 |
Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells.
Topics: AMP-Activated Protein Kinases; Antineoplastic Agents; Benzoates; Catechin; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; Humans; Naphthalenes; Neoplastic Stem Cells; Signal Transduction; TOR Serine-Threonine Kinases; Up-Regulation | 2012 |
A novel approach for addressing Alzheimer's disease: the chemo-optical synergism.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Catechin; Humans; Laser Therapy; Neuroprotective Agents | 2012 |
EGCG inhibits Tat-induced LTR transactivation: role of Nrf2, AKT, AMPK signaling pathway.
Topics: Antioxidants; Blotting, Western; Catechin; Cell Line; Cell Nucleus; Cell Survival; Cells, Cultured; Gene Silencing; Glutathione; HIV Long Terminal Repeat; Humans; I-kappa B Kinase; Immunoprecipitation; Mitogen-Activated Protein Kinases; NADPH Oxidases; NF-E2-Related Factor 2; Protease Inhibitors; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; tat Gene Products, Human Immunodeficiency Virus; Tea; Transcription Factor RelA; Transcriptional Activation; Transfection | 2012 |
Efficacy of food proteins as carriers for flavonoids.
Topics: Animals; Catechin; Cattle; Chickens; Dietary Supplements; Drug Carriers; Egg Proteins; Fish Proteins; Fishes; Gelatin; Kinetics; Milk Proteins; Protein Binding | 2012 |
Selective death of cancer cells by preferential induction of reactive oxygen species in response to (-)-epigallocatechin-3-gallate.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cyclin-Dependent Kinase Inhibitor p21; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; HCT116 Cells; HEK293 Cells; Humans; Neoplasms; Reactive Oxygen Species; Telomerase; Tumor Suppressor Protein p53; Up-Regulation | 2012 |
Heat shock protein 27 expression in areca quid chewing-associated oral squamous cell carcinomas.
Topics: Acetylcysteine; Areca; Arecoline; Carcinoma, Squamous Cell; Case-Control Studies; Catechin; Cyclooxygenase 2 Inhibitors; Down-Regulation; Female; Flavonoids; Gene Expression; Gene Expression Regulation, Neoplastic; HSP27 Heat-Shock Proteins; Humans; Imidazoles; Male; Middle Aged; Mouth Neoplasms; Nitrobenzenes; Pyridines; Quercetin; Sulfonamides | 2012 |
(-)-Epigallocatechin-3-gallate inhibits the replication cycle of hepatitis C virus.
Topics: Antiviral Agents; Apoptosis; Catechin; Cell Line; Dose-Response Relationship, Drug; Gene Expression Regulation, Viral; Hepacivirus; Humans; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Virus Internalization; Virus Replication | 2012 |
Nutraceutical-mediated restoration of wild-type levels of IKBKAP-encoded IKAP protein in familial dysautonomia-derived cells.
Topics: Blotting, Western; Carrier Proteins; Catechin; Dietary Supplements; Drug Synergism; Dysautonomia, Familial; Fibroblasts; Genistein; Genotype; HEK293 Cells; Humans; Isoflavones; Neurons; Phosphotransferases (Phosphate Group Acceptor); Reverse Transcriptase Polymerase Chain Reaction; RNA Splicing; Transcriptional Elongation Factors; Up-Regulation | 2012 |
Green tea (-)-epigallocatechin gallate inhibits IGF-I and IGF-II stimulation of 3T3-L1 preadipocyte mitogenesis via the 67-kDa laminin receptor, but not AMP-activated protein kinase pathway.
Topics: 3T3-L1 Cells; Adenosine Monophosphate; Adipocytes; Animals; Antioxidants; Catechin; Cell Proliferation; Immunoprecipitation; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Mice; Mitogen-Activated Protein Kinases; Phosphorylation; Plant Extracts; Receptor, IGF Type 1; Receptor, IGF Type 2; Receptors, Laminin; Tea | 2012 |
(-)-Epigallocatechin-3-gallate, a green tea-derived catechin, synergizes with celecoxib to inhibit IL-1-induced tumorigenic mediators by human pancreatic adenocarcinoma cells Colo357.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Camellia sinensis; Caspases; Catechin; Celecoxib; Cell Line, Tumor; Cyclooxygenase 2; Drug Synergism; Humans; Interleukin-1; Pancreatic Neoplasms; Pyrazoles; Sulfonamides | 2012 |
Alterations in expression of specific microRNAs by combination of 4-HPR and EGCG inhibited growth of human malignant neuroblastoma cells.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Survival; Fenretinide; Humans; MicroRNAs; Neuroblastoma | 2012 |
Epigallocatechin-3-gallate has an anti-platelet effect in a cyclic AMP-dependent manner.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Animals; Catechin; Collagen; Cyclic AMP; Cyclic GMP; Male; Phosphorylation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley | 2012 |
EGCG suppresses prostate cancer cell growth modulating acetylation of androgen receptor by anti-histone acetyltransferase activity.
Topics: Acetylation; Androgen Receptor Antagonists; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Chemoprevention; Histone Acetyltransferases; Humans; Male; Prostatic Neoplasms; Receptors, Androgen; Transcription, Genetic | 2012 |
Experimental and theoretical studies on the binding of epigallocatechin gallate to purified porcine gastric mucin.
Topics: Animals; Catechin; Gastric Mucins; Humans; Models, Molecular; Protein Binding; Solutions; Swine; Thermodynamics | 2012 |
Survivin knockdown increased anti-cancer effects of (-)-epigallocatechin-3-gallate in human malignant neuroblastoma SK-N-BE2 and SH-SY5Y cells.
Topics: Antineoplastic Agents; Apoptosis; Base Sequence; Caspases; Catechin; Cell Differentiation; Cell Line, Tumor; Cell Movement; Gene Knockdown Techniques; Humans; Inhibitor of Apoptosis Proteins; Neovascularization, Pathologic; Neuroblastoma; RNA, Messenger; RNA, Neoplasm; RNA, Small Interfering; Survivin | 2012 |
EGCG protects endothelial cells against PCB 126-induced inflammation through inhibition of AhR and induction of Nrf2-regulated genes.
Topics: Animals; Catechin; Cells, Cultured; Chemokine CCL2; Cytochrome P-450 CYP1A1; Cytoprotection; Endothelial Cells; Gene Expression Regulation; Glutathione Transferase; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Polychlorinated Biphenyls; Receptors, Aryl Hydrocarbon; Swine; Vascular Cell Adhesion Molecule-1 | 2012 |
Effects of epigallocatechin-3-gallate on pentylenetetrazole-induced kindling, cognitive impairment and oxidative stress in rats.
Topics: Animals; Brain; Catechin; Cognition; Convulsants; Kindling, Neurologic; Male; Maze Learning; Neuroprotective Agents; Oxidative Stress; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures | 2012 |
Radio-modulatory effects of green tea catechin EGCG on pBR322 plasmid DNA and murine splenocytes against gamma-radiation induced damage.
Topics: Animals; Antimutagenic Agents; Antioxidants; Catechin; Cell Death; DNA Damage; Gamma Rays; Lipid Peroxidation; Mice; Radiation-Protective Agents; Spleen; Tea | 2012 |
Thermodynamic analysis of the molecular interactions between amyloid β-protein fragments and (-)-epigallocatechin-3-gallate.
Topics: Amyloid beta-Peptides; Calorimetry; Catechin; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Peptide Fragments; Salts; Thermodynamics | 2012 |
Investigation into the mechanism of (-)-epigallocatechin-3-gallate-induced precipitation of insulin.
Topics: Catechin; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Insulin; Kinetics; Protein Binding; Salts; Solubility; Solutions | 2012 |
Influence of pH on the speciation of copper(II) in reactions with the green tea polyphenols, epigallocatechin gallate and gallic acid.
Topics: Catechin; Cations, Divalent; Copper; Electron Spin Resonance Spectroscopy; Gallic Acid; Hydrogen-Ion Concentration; Molecular Structure; Organometallic Compounds; Polymerization; Polyphenols; Tea | 2012 |
Green tea polyphenols increase p53 transcriptional activity and acetylation by suppressing class I histone deacetylases.
Topics: Acetylation; Apoptosis; bcl-2-Associated X Protein; Camellia sinensis; Catechin; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; G1 Phase Cell Cycle Checkpoints; Gene Expression; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Male; Plant Extracts; Polyphenols; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Binding; Protein Processing, Post-Translational; Protein Stability; Transcriptional Activation; Tumor Suppressor Protein p53 | 2012 |
Prostanoid EP1 receptor as the target of (-)-epigallocatechin-3-gallate in suppressing hepatocellular carcinoma cells in vitro.
Topics: Alprostadil; Antineoplastic Agents, Phytogenic; Blotting, Western; Bridged Bicyclo Compounds; Caproates; Carcinoma, Hepatocellular; Catechin; Cell Movement; Cell Proliferation; Cell Survival; Dinoprostone; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits, Gq-G11; Hep G2 Cells; Humans; Immunoassay; Liver Neoplasms; Neoplasm Invasiveness; Receptors, Prostaglandin E, EP1 Subtype; Time Factors | 2012 |
Antibacterial activity of ammonium hexafluorosilicate solution with antimicrobial agents for the prevention of dentin caries.
Topics: Acid Etching, Dental; Anti-Bacterial Agents; Anti-Infective Agents, Local; Bacterial Adhesion; Bacterial Load; Biofilms; Cariostatic Agents; Catechin; Cetylpyridinium; Chlorhexidine; Dental Caries; Dentin; Durapatite; Fluorides; Humans; Materials Testing; Microscopy, Electron, Scanning; Phenols; Phosphoric Acids; Silicic Acid; Silver Compounds; Streptococcus mutans; Wettability | 2012 |
Epigallocatechin-3-gallate induces mesothelioma cell death via H2 O2 -dependent T-type Ca2+ channel opening.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Calcium; Calcium Channels, T-Type; Catalase; Catechin; Cell Death; Cell Line, Tumor; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Humans; Hydrogen Peroxide; Mesothelioma; Mibefradil; Pleura; Pleural Neoplasms; Reactive Oxygen Species | 2012 |
The synergistic apoptotic interaction of panaxadiol and epigallocatechin gallate in human colorectal cancer cells.
Topics: Annexin A5; Apoptosis; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Drug Synergism; Ginsenosides; Humans; Molecular Docking Simulation | 2013 |
Isolation and characterization of phenolic antioxidants from Plantago herb.
Topics: Acetates; Antioxidants; Catechin; Ethanol; Glycosides; Oxidation-Reduction; Phenols; Plant Extracts; Plantago; Water | 2012 |
(-)-Epigallocatechin-3-gallate (EGCG) attenuates functional deficits and morphological alterations by diminishing apoptotic gene overexpression in skeletal muscles after sciatic nerve crush injury.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Behavior, Animal; Catechin; Desmin; Foot; Hot Temperature; Hyperalgesia; Immunohistochemistry; Male; Muscle, Skeletal; Nerve Crush; Neuroprotective Agents; Pain Measurement; Posture; Rats; Rats, Wistar; Reaction Time; Real-Time Polymerase Chain Reaction; Recovery of Function; RNA; Sciatic Neuropathy; Signal Transduction; Toes | 2012 |
Inhibitory effects of (-)-epigallocatechin-3-gallate and pterostilbene on pancreatic cancer growth in vitro.
Topics: Anticarcinogenic Agents; Carcinoma; Caspases; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cytochromes c; DNA Fragmentation; Drug Evaluation, Preclinical; Humans; Pancreatic Neoplasms; Stilbenes | 2012 |
Quercetin and epigallocatechin gallate induce in vitro a dose-dependent stiffening and hyperpolarizing effect on the cell membrane of human mononuclear blood cells.
Topics: Adult; Aged; Anisotropy; Biomarkers; Cardiovascular Diseases; Catechin; Cell Membrane; Cell Polarity; Diabetes Mellitus, Type 2; Diet, Vegetarian; Female; Humans; Hyperglycemia; Inflammation; Insulin; Insulin Resistance; Leukocytes, Mononuclear; Male; Membrane Fluidity; Membrane Potentials; Middle Aged; Quercetin; Resistin | 2012 |
An enzyme-coupled high-throughput assay for screening RNA methyltransferase activity in E. coli cell lysate.
Topics: Caffeic Acids; Catechin; Chlorogenic Acid; Chromogenic Compounds; Dithionitrobenzoic Acid; Enzyme Assays; Enzyme Inhibitors; Escherichia coli; High-Throughput Screening Assays; Homocysteine; Humans; Methyltransferases; Placental Lactogen; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2012 |
The preparation and characterization of gold-conjugated polyphenol nanoparticles as a novel delivery system.
Topics: Animals; Antineoplastic Agents; Antioxidants; Catechin; Cell Survival; Chromatography, High Pressure Liquid; Drug Carriers; Drug Stability; Female; Gold; Hydrogen-Ion Concentration; Metal Nanoparticles; Mice; Mice, Inbred C3H; Microsomes, Liver; Neoplasms, Experimental; Particle Size; Time Factors; Xenograft Model Antitumor Assays | 2012 |
NF-κΒ inhibition is ineffective in blocking cytokine-induced IL-8 production but P38 and STAT1 inhibitors are effective.
Topics: Caco-2 Cells; Catechin; Cell Line; Cytokines; Genes, Reporter; Humans; Imidazoles; NF-kappa B; Nitric Oxide; Nitriles; p38 Mitogen-Activated Protein Kinases; Proline; Protein Kinase Inhibitors; Pyridines; STAT1 Transcription Factor; Sulfones; Thiocarbamates | 2012 |
Natural polyphenols as modulators of TTR amyloidogenesis: in vitro and in vivo evidences towards therapy.
Topics: Amyloid Neuropathies, Familial; Animals; Blotting, Western; Catechin; Curcumin; Gastrointestinal Tract; Immunohistochemistry; Masoprocol; Mice; Peripheral Nervous System; Polyphenols; Prealbumin | 2012 |
Green tea catechins decrease oxidative stress in surgical menopause-induced overactive bladder in a rat model.
Topics: Animals; Antioxidants; Catechin; Disease Models, Animal; Female; Menopause; Ovariectomy; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Tea; Urinary Bladder, Overactive | 2012 |
Combined administration of EGCG and IL-1 receptor antagonist efficiently downregulates IL-1-induced tumorigenic factors in U-2 OS human osteosarcoma cells.
Topics: Antineoplastic Agents; Caspase 3; Catechin; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Drug Synergism; Enzyme Activation; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-6; Interleukin-8; Matrix Metalloproteinase 2; Osteosarcoma; Receptors, Interleukin-1; Vascular Endothelial Growth Factor A | 2012 |
Delphinidin-3-O-galactoside protects mouse hepatocytes from (-)-epigallocatechin-3-gallate-induced cytotoxicity via up-regulation of heme oxygenase-1 and heat shock protein 70.
Topics: Animals; Anthocyanins; Antioxidants; Catechin; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Galactosides; Heme Oxygenase-1; Hepatocytes; HSP70 Heat-Shock Proteins; Mice; Phytotherapy; Plant Extracts; RNA, Messenger; Up-Regulation | 2012 |
Green tea polyphenol EGCG sensing motif on the 67-kDa laminin receptor.
Topics: Amino Acid Motifs; Amino Acid Sequence; Catechin; Cell Proliferation; Extracellular Space; Hep G2 Cells; Humans; Molecular Sequence Data; Polyphenols; Protein Binding; Protein Structure, Tertiary; Receptors, Laminin; Ribosomal Proteins; Tea | 2012 |
Apple pectin affects the efficacy of epigallocatechin gallate on oral sucrose tolerance test in adult mice.
Topics: Animals; Blood Glucose; Catechin; Cellulose; Dietary Fiber; Lipids; Male; Malus; Mice; Mice, Inbred ICR; Pectins; Sucrose | 2011 |
Sensitive determination of (-)-epigallocatechin gallate in tea infusion using a novel ionic liquid carbon paste electrode.
Topics: Carbon; Catechin; Electrochemistry; Electrodes; Ionic Liquids; Oxidation-Reduction; Sensitivity and Specificity; Tea | 2012 |
Curcumin and other polyphenolic compounds in head and neck cancer chemoprevention.
Topics: Antimutagenic Agents; Catechin; Cell Survival; Cells, Cultured; Curcumin; DNA Damage; Head and Neck Neoplasms; Humans; Nicotiana; Polyphenols | 2012 |
Green tea epigallocatechin-3-gallate (EGCG) promotes neural progenitor cell proliferation and sonic hedgehog pathway activation during adult hippocampal neurogenesis.
Topics: Age Factors; Animals; Catechin; Cell Proliferation; Cells, Cultured; Dentate Gyrus; Hedgehog Proteins; Hippocampus; Kruppel-Like Transcription Factors; Learning; Male; Memory; Mice; Mice, Inbred C57BL; Neurogenesis; Neurons; Patched Receptors; Receptors, Cell Surface; Signal Transduction; Stem Cells; Tea; Zinc Finger Protein GLI1 | 2012 |
EGCG targeting efficacy of NF-κB downstream gene products is dictated by the monocytic/macrophagic differentiation status of promyelocytic leukemia cells.
Topics: Biomarkers, Tumor; Blood-Brain Barrier; Catechin; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cyclooxygenase 2; HL-60 Cells; Humans; I-kappa B Proteins; Leukemia, Promyelocytic, Acute; Macrophages; Matrix Metalloproteinase 9; Monocytes; NF-kappa B; Phosphorylation; Receptors, Laminin; Signal Transduction; Transcription, Genetic | 2012 |
Interaction of (-)-epigallocatechin gallate with lysozyme-conjugated silver nanoparticles.
Topics: Catechin; Circular Dichroism; Colloids; Metal Nanoparticles; Models, Molecular; Muramidase; Protein Binding; Protein Conformation; Silver; Spectrum Analysis, Raman | 2012 |
Deleterious effects of high concentrations of (-)-epigallocatechin-3-gallate and atorvastatin in mice with colon inflammation.
Topics: Animals; Atorvastatin; Azoxymethane; Catechin; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gastrointestinal Hemorrhage; Heptanoic Acids; Leukotriene B4; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Pyrroles; Rectum; Weight Loss | 2012 |
Mitochondrial damage contribute to epigallocatechin-3-gallate induced death in Leishmania amazonensis.
Topics: Antioxidants; Antiprotozoal Agents; Catechin; Dose-Response Relationship, Drug; Leishmania mexicana; Membrane Potential, Mitochondrial; Microscopy, Electron, Transmission; Mitochondria; Time Factors | 2012 |
Effects of efflux pump inhibitors on erythromycin, ciprofloxacin, and tetracycline resistance in Campylobacter spp. isolates.
Topics: Animals; Anti-Bacterial Agents; Campylobacter coli; Campylobacter jejuni; Catechin; Ciprofloxacin; Dipeptides; Drug Resistance, Multiple, Bacterial; Erythromycin; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Piperazines; Tetracycline Resistance | 2012 |
Epigallocatechin-3-gallate suppresses 1-methyl-4-phenyl-pyridine-induced oxidative stress in PC12 cells via the SIRT1/PGC-1α signaling pathway.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antioxidants; Camellia sinensis; Catechin; Cell Survival; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Oxidative Stress; Parkinson Disease; PC12 Cells; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phytotherapy; Plant Extracts; Rats; Reactive Oxygen Species; RNA-Binding Proteins; RNA, Messenger; Signal Transduction; Sirtuin 1; Superoxide Dismutase; Superoxide Dismutase-1; Tea; Transcription Factors; Up-Regulation | 2012 |
Inhibition of Eph receptor-ephrin ligand interaction by tea polyphenols.
Topics: Animals; Catechin; Cell Line; Chlorocebus aethiops; COS Cells; Ephrins; Mice; Polyphenols; Protein Binding; Protein Interaction Maps; Receptor, EphA4; Receptors, Eph Family; Signal Transduction; Small Molecule Libraries; Tea | 2012 |
Epigallocatechin gallate reduces vascular inflammation in db/db mice possibly through an NF-κB-mediated mechanism.
Topics: Animals; Antioxidants; Aorta; Catechin; Cell Adhesion; Cell Line; Diabetes Mellitus, Experimental; Dietary Supplements; Endothelial Cells; Humans; Hyperglycemia; Inflammation; Male; Mice; Mice, Inbred Strains; Monocytes; Tea; Transcription Factor RelA | 2012 |
Early apoptosis signals induced by a low dose of epigallocatechin 3-gallate interfere with apoptotic and cell death pathways.
Topics: Apoptosis; Catechin; Dose-Response Relationship, Drug; Flow Cytometry; HeLa Cells; Humans; Signal Transduction | 2012 |
Pro-apoptotic effect of epigallo-catechin-3-gallate on B lymphocytes through regulating BAFF/PI3K/Akt/mTOR signaling in rats with collagen-induced arthritis.
Topics: Animals; Ankle Joint; Apoptosis; Apoptosis Regulatory Proteins; Arthritis, Experimental; B-Cell Activating Factor; B-Cell Activation Factor Receptor; B-Lymphocytes; Bcl-2-Like Protein 11; bcl-X Protein; Catechin; Cell Proliferation; Collagen Type II; Gene Expression Regulation, Enzymologic; Immunoglobulin Isotypes; Male; Mechanistic Target of Rapamycin Complex 1; Membrane Proteins; Multiprotein Complexes; Phosphatidylinositol 3-Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Spleen; TOR Serine-Threonine Kinases | 2012 |
Epigallocatechin-3-gallate suppresses IGF-I-induced lipogenesis and cytokine expression in SZ95 sebocytes.
Topics: Acne Vulgaris; Administration, Topical; Animals; Anti-Inflammatory Agents; Apoptosis; Catechin; Cell Line, Transformed; Cell Proliferation; Cytokines; Ear Auricle; Female; Humans; Insulin-Like Growth Factor I; Interleukin-1; Interleukin-6; Interleukin-8; Lipogenesis; Rabbits; Sebaceous Glands; Sebum; Signal Transduction | 2012 |
(-)-Epigallocatechin gallate inhibits endotoxin-induced expression of inflammatory cytokines in human cerebral microvascular endothelial cells.
Topics: Blood-Brain Barrier; Catechin; Cell Line, Transformed; Cytokines; Endothelium, Vascular; Endotoxins; Gene Expression Regulation; Humans; Inflammation Mediators; Microcirculation | 2012 |
Different fatty acid metabolism effects of (-)-epigallocatechin-3-gallate and C75 in adenocarcinoma lung cancer.
Topics: 4-Butyrolactone; Adenocarcinoma; Adenocarcinoma of Lung; Analysis of Variance; Animals; Apoptosis; Carnitine O-Palmitoyltransferase; Catechin; Cell Line, Tumor; Fatty Acid Synthases; Fatty Acids; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; Random Allocation; Signal Transduction; Weight Loss; Xenograft Model Antitumor Assays | 2012 |
Epigallocatechin gallate enhances biliary cholesterol secretion in healthy rats and lowers plasma and liver cholesterol in ethinylestradiol-treated rats.
Topics: Animals; Biliary Tract; Biological Transport; Catechin; Cholesterol; Ethinyl Estradiol; Female; Gene Expression Regulation; Health; Intestinal Absorption; Liver; Phospholipids; Rats; Rats, Wistar | 2012 |
Laminin receptor specific therapeutic gold nanoparticles (198AuNP-EGCg) show efficacy in treating prostate cancer.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Female; Gold; Gold Radioisotopes; Humans; Male; Metal Nanoparticles; Mice; Mice, SCID; Particle Size; Prostatic Neoplasms; Xenograft Model Antitumor Assays | 2012 |
Beneficial effects of (-)-epigallocatechin gallate on ischemia-reperfusion testicular injury in rats.
Topics: Animals; Antioxidants; Biomarkers; Catechin; Disease Models, Animal; Male; Postoperative Complications; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Spermatic Cord Torsion | 2012 |
Cyclin D1 degradation and p21 induction contribute to growth inhibition of colorectal cancer cells induced by epigallocatechin-3-gallate.
Topics: Apoptosis; Caco-2 Cells; Caspase 3; Caspase 7; Catechin; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; HCT116 Cells; HT29 Cells; Humans; MAP Kinase Signaling System; NF-kappaB-Inducing Kinase; Phosphatidylinositol 3-Kinases; Phosphorylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proteolysis; Signal Transduction; Ubiquitination; Up-Regulation | 2012 |
Protective effects of (-)-epigallocatechin-3-gallate against TNF-α-induced lung inflammation via ROS-dependent ICAM-1 inhibition.
Topics: Activating Transcription Factor 2; Animals; Catechin; Cell Line; Extracellular Signal-Regulated MAP Kinases; Heme Oxygenase-1; Humans; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred ICR; NADPH Oxidases; Phosphorylation; Pneumonia; Protective Agents; Reactive Oxygen Species; Receptors, Tumor Necrosis Factor, Type I; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; TNF Receptor-Associated Factor 2; Tumor Necrosis Factor-alpha | 2013 |
Detailed analysis of apoptosis and delayed luminescence of human leukemia Jurkat T cells after proton irradiation and treatments with oxidant agents and flavonoids.
Topics: Apoptosis; Catechin; Cell Cycle; Cell Survival; Clone Cells; Flavonoids; Humans; Hydrogen Peroxide; Jurkat Cells; Kinetics; Leukemia; Luminescence; NADP; Oxidants; Protons; Quantum Theory; Quercetin; Time Factors; Vitamin K 3 | 2012 |
Preconditioning and acute effects of flavonoids in protecting cardiomyocytes from oxidative cell death.
Topics: Animals; Ascorbic Acid; Cardiotonic Agents; Catechin; Cell Death; Cell Line; Culture Media, Serum-Free; Cytoprotection; Flavonoids; Glucose; Glyceraldehyde-3-Phosphate Dehydrogenases; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidation-Reduction; Oxidative Stress; Oxygen; Quercetin; Rats; tert-Butylhydroperoxide; Time Factors | 2012 |
Protection against oxidative DNA damage and stress in human prostate by glutathione S-transferase P1.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Catechin; Cell Line; Deoxyguanosine; DNA Damage; Enzyme Activation; Epithelial Cells; Gene Expression Regulation, Neoplastic; Glutathione S-Transferase pi; Guanosine Triphosphate; Humans; Hydrogen Peroxide; Male; Oxidative Stress; Prostate; Prostatic Neoplasms; Reactive Oxygen Species | 2014 |
Green tea and its major polyphenol EGCG increase the activity of oral peroxidases.
Topics: Antioxidants; Catechin; Humans; Oxidative Stress; Peroxidases; Saliva; Tea | 2013 |
Opposite effects of quercetin, luteolin, and epigallocatechin gallate on insulin sensitivity under normal and inflammatory conditions in mice.
Topics: 3T3 Cells; Adipose Tissue; Animals; Biological Transport; Blood Glucose; Catechin; Cell Line; Culture Media, Conditioned; Glucose; Glucose Tolerance Test; I-kappa B Kinase; Inflammation; Insulin Receptor Substrate Proteins; Insulin Resistance; Luteolin; Macrophages; Male; Mice; Mice, Inbred ICR; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Quercetin | 2013 |
Epigallocatechin-3-gallate diminishes cytokine-stimulated Cyr61 expression in human osteoblastic cells: a therapeutic potential for arthritis.
Topics: Adult; Animals; Arthritis; Catechin; Cells, Cultured; Chemokine CCL2; Chromones; Cysteine-Rich Protein 61; Cytokines; Enzyme Inhibitors; Humans; Inositol Phosphates; Male; Morpholines; NF-kappa B; Osteoblasts; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Young Adult | 2012 |
A modulating effect of epigallocatechin gallate (EGCG), a tea catechin, on the bladder of rats exposed to water avoidance stress.
Topics: Animals; Catechin; Cell Degranulation; Cystitis, Interstitial; Defecation; Disease Models, Animal; Female; Immersion; Injections, Intraperitoneal; Mast Cells; Rats; Rats, Sprague-Dawley; Stress, Psychological; Time Factors; Urinary Bladder; Urination; Water | 2013 |
Epigallocatechin-3-gallate modulates antioxidant and DNA repair-related proteins in exocrine glands of a primary Sjogren's syndrome mouse model prior to disease onset.
Topics: Animals; Antibodies, Antinuclear; Antioxidants; Catechin; Disease Models, Animal; DNA Repair; Exocrine Glands; Female; Lymphocytes; Mice; Mice, Inbred NOD; Peroxiredoxin VI; Proliferating Cell Nuclear Antigen; Sjogren's Syndrome; Time Factors | 2012 |
Inhibition of the intracellular Ca(2+) transporter SERCA (Sarco-Endoplasmic Reticulum Ca(2+)-ATPase) by the natural polyphenol epigallocatechin-3-gallate.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Calcium; Catechin; Dose-Response Relationship, Drug; Female; Microsomes; Muscle Proteins; Muscle, Skeletal; Phosphates; Phosphorylation; Rabbits; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2012 |
Comparison of three amyloid assembly inhibitors: the sugar scyllo-inositol, the polyphenol epigallocatechin gallate, and the molecular tweezer CLR01.
Topics: Amyloid beta-Peptides; Animals; Bridged-Ring Compounds; Catechin; Inositol; Organophosphates; Peptide Fragments; Polyphenols; Rats; Rats, Sprague-Dawley | 2012 |
A cell-based, microplate colorimetric screen identifies 7,8-benzoflavone and green tea gallate catechins as inhibitors of the hepatitis C virus.
Topics: Antiviral Agents; Benzoflavones; Camellia sinensis; Catechin; Cell Line, Tumor; Cyclosporine; Drug Evaluation, Preclinical; Flavones; Hepacivirus; Hepatitis C; Humans; Phytotherapy; Reproducibility of Results; Tamoxifen | 2012 |
Effect of (-)-epigallocatechin gallate on electrochemical behavior and surface film composition of Co-Cr alloy used in dental restorations.
Topics: Catechin; Chromium Alloys; Cobalt; Corrosion; Dielectric Spectroscopy; Electrochemical Techniques; Photoelectron Spectroscopy; Saliva, Artificial; Spectrophotometry, Atomic; Surface Properties; Tea | 2012 |
Green tea catechins increase the force of contraction in isolated guinea pig atrial muscle preparations by increasing the amplitude of intracellular Ca2+ concentration.
Topics: Animals; Calcium; Camellia sinensis; Catechin; Dose-Response Relationship, Drug; Guinea Pigs; Heart Atria; Male; Molecular Structure; Myocardial Contraction; Plant Extracts; Regression Analysis | 2012 |
Green tea polyphenols precondition against cell death induced by oxygen-glucose deprivation via stimulation of laminin receptor, generation of reactive oxygen species, and activation of protein kinase Cε.
Topics: Animals; Antioxidants; Catechin; Cell Death; Cell Membrane; Cytosol; Enzyme Activation; Glucose; Oxygen; PC12 Cells; Polyphenols; Protein Binding; Protein Kinase C-epsilon; Protein Transport; Rats; Reactive Oxygen Species; Receptors, Laminin; Tea | 2012 |
Oxygen partial pressure modulates 67-kDa laminin receptor expression, leading to altered activity of the green tea polyphenol, EGCG.
Topics: Animals; Antineoplastic Agents, Phytogenic; Base Sequence; Catechin; Cell Line, Tumor; Cell Proliferation; DNA Primers; HeLa Cells; Hep G2 Cells; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Melanoma, Experimental; Mice; Oxygen; Proteasome Inhibitors; Reactive Oxygen Species; Receptors, Laminin; Ubiquitination | 2012 |
Catechins protect neurons against mitochondrial toxins and HIV proteins via activation of the BDNF pathway.
Topics: Animals; Anti-HIV Agents; Brain-Derived Neurotrophic Factor; Catechin; Embryo, Mammalian; Gene Expression Regulation; High-Throughput Screening Assays; Hippocampus; HIV Envelope Protein gp120; Humans; Mitochondria; Neurons; Neuroprotective Agents; Nitro Compounds; Oxidative Stress; Primary Cell Culture; Propionates; Protein Precursors; Rats; Resveratrol; Signal Transduction; Stereoisomerism; Stilbenes; tat Gene Products, Human Immunodeficiency Virus | 2012 |
Neutralizing effect of green tea epigallocatechin-3-gallate on nicotine-induced toxicity and chemokine (C-C motif) ligand 5 secretion in human oral epithelial cells and fibroblasts.
Topics: Aggregatibacter actinomycetemcomitans; Catechin; Cells, Cultured; Chemokine CCL5; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Fibroblasts; Humans; Lipopolysaccharides; Nicotine; Polyphenols; Tea | 2012 |
The polyphenol EGCG inhibits amyloid formation less efficiently at phospholipid interfaces than in bulk solution.
Topics: Catechin; Humans; Islet Amyloid Polypeptide; Microscopy, Atomic Force; Models, Molecular; Molecular Structure; Particle Size; Phospholipids; Polyphenols; Solutions; Spectrum Analysis; Surface Properties | 2012 |
Antitumor activity of the tea polyphenol epigallocatechin-3-gallate encapsulated in targeted vesicles after intravenous administration.
Topics: Administration, Intravenous; Animals; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Female; Humans; Melanoma; Mice; Mice, Inbred BALB C; Microscopy, Electron, Transmission; Tea; Xenograft Model Antitumor Assays | 2013 |
Epigallocatechin gallate promotes the vasorelaxation power of the antiatherosclerotic dipeptide Trp-His in contracted rat aorta.
Topics: Animals; Aorta; Cardiovascular Diseases; Catechin; Dipeptides; Drug Synergism; Humans; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents | 2012 |
Coordinated regulation of murine cardiomyocyte contractility by nanomolar (-)-epigallocatechin-3-gallate, the major green tea catechin.
Topics: Animals; Biological Transport; Calcium; Catechin; Cell Membrane; Cell Size; In Vitro Techniques; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocytes, Cardiac; Rabbits; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Stereoisomerism; Tea | 2012 |
Antiproliferative and apoptotic effect of epigallocatechin-3-gallate on Ishikawa cells is accompanied by sex steroid receptor downregulation.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Caspases; Catechin; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Enzyme Activation; Estradiol; Extracellular Signal-Regulated MAP Kinases; G1 Phase Cell Cycle Checkpoints; Gene Expression; Humans; MAP Kinase Signaling System; Proto-Oncogene Proteins c-akt; Receptors, Estrogen; Receptors, Progesterone | 2012 |
Epigallocatechin gallate sensitizes CAL-27 human oral squamous cell carcinoma cells to the anti-metastatic effects of gefitinib (Iressa) via synergistic suppression of epidermal growth factor receptor and matrix metalloproteinase-2
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Drug Synergism; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Gefitinib; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Mouth Neoplasms; Neoplasm Metastasis; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Wound Healing | 2012 |
Radioprotective effects of (-)-epigallocatechin-3-gallate on human erythrocyte/granulocyte lineages.
Topics: Antigens, CD34; Catechin; Cell Lineage; Erythrocytes; Erythropoietin; Female; Granulocyte Colony-Stimulating Factor; Granulocytes; Hematopoietic Stem Cells; Humans; Placenta; Pregnancy; Radiation-Protective Agents; Recombinant Proteins; Stem Cells; Umbilical Cord; X-Rays | 2012 |
Cavernous antioxidant effect of green tea, epigallocatechin-3-gallate with/without sildenafil citrate intake in aged diabetic rats.
Topics: Animals; Antioxidants; Catechin; Diabetes Complications; Drug Evaluation, Preclinical; Drug Therapy, Combination; Erectile Dysfunction; Male; Penis; Phosphodiesterase 5 Inhibitors; Phytotherapy; Piperazines; Purines; Rats; Sildenafil Citrate; Sulfones; Tea | 2013 |
The dual action of epigallocatechin gallate (EGCG), the main constituent of green tea, against the deleterious effects of visible light and singlet oxygen-generating conditions as seen in yeast cells.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Catechin; Light; Oxidative Stress; Photosensitizing Agents; Reactive Oxygen Species; Saccharomyces cerevisiae; Singlet Oxygen; Solvents; Tea; Ultraviolet Rays | 2012 |
Influence of gallate and pyrogallol moieties on the intestinal absorption of (-)-epicatechin and (-)-epicatechin gallate.
Topics: Biological Availability; Caco-2 Cells; Catechin; Functional Food; Humans; Intestinal Absorption; Pyrogallol; Structure-Activity Relationship; Tea | 2012 |
Epigallocatechin-3-gallate inhibits bladder cancer cell invasion via suppression of NF-κB‑mediated matrix metalloproteinase-9 expression.
Topics: Anticarcinogenic Agents; Catechin; Cell Adhesion; Cell Line, Tumor; Cell Movement; Down-Regulation; Fibronectins; Humans; Matrix Metalloproteinase 9; NF-kappa B; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; RNA, Messenger; Urinary Bladder Neoplasms | 2012 |
Epigallocatechin gallate induces upregulation of the two-component VraSR system by evoking a cell wall stress response in Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Catechin; Cell Wall; DNA-Binding Proteins; Drug Tolerance; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Gene Knockout Techniques; Lysostaphin; Oxacillin; Real-Time Polymerase Chain Reaction; Signal Transduction; Staphylococcus aureus | 2012 |
Amelioration of influenza virus-induced reactive oxygen species formation by epigallocatechin gallate derived from green tea.
Topics: Animals; Antiviral Agents; Camellia sinensis; Catechin; Cell Line; Cell Survival; Dogs; Dose-Response Relationship, Drug; Erythrocytes; Guinea Pigs; Hemagglutination Tests; Hemagglutination, Viral; Influenza A Virus, H1N1 Subtype; Lung; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Pneumonia, Viral; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction | 2012 |
Tea phenols in bulk and nanoparticle form modify DNA damage in human lymphocytes from colon cancer patients and healthy individuals treated in vitro with platinum-based chemotherapeutic drugs.
Topics: Antineoplastic Agents; Antioxidants; Catechin; Cell Survival; Chemoprevention; Cisplatin; Colonic Neoplasms; DNA Damage; Flavonoids; Humans; Lymphocytes; Nanoparticles; Particle Size; Polymers; Reactive Oxygen Species; Tea | 2013 |
A plant cell-based system that predicts aβ42 misfolding: potential as a drug discovery tool for Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Catechin; Cell Engineering; Curcumin; Drug Evaluation, Preclinical; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; Humans; Microscopy, Fluorescence; Models, Biological; Mutation; Nicotiana; Peptide Fragments; Phosphotransferases (Alcohol Group Acceptor); Plant Cells; Protein Binding; Protein Conformation; Protein Folding; Recombinant Fusion Proteins; Resveratrol; Stilbenes | 2012 |
Prodrug of green tea epigallocatechin-3-gallate (Pro-EGCG) as a potent anti-angiogenesis agent for endometriosis in mice.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Biological Availability; Catechin; Endometriosis; Endometrium; Female; Mice; Neovascularization, Pathologic; Ovarian Follicle; Oxidation-Reduction; Prodrugs; Tea | 2013 |
EGCG inhibits transforming growth factor-β-mediated epithelial-to-mesenchymal transition via the inhibition of Smad2 and Erk1/2 signaling pathways in nonsmall cell lung cancer cells.
Topics: Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Down-Regulation; Epithelial-Mesenchymal Transition; Humans; Lung Neoplasms; MAP Kinase Signaling System; Plant Extracts; Smad2 Protein; Transforming Growth Factor beta | 2012 |
Epigallocatechin-3-gallate prevents systemic inflammation-induced memory deficiency and amyloidogenesis via its anti-neuroinflammatory properties.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Behavior, Animal; Catechin; Cells, Cultured; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Inflammation; Lipopolysaccharides; Male; Memory Disorders; Mice; Mice, Inbred ICR; Neurons; Nitric Oxide Synthase Type II; Peptide Fragments; Rats | 2013 |
(-)-Epigallocatechin-3-gallate induces apoptosis in human endometrial adenocarcinoma cells via ROS generation and p38 MAP kinase activation.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; Endometrial Neoplasms; Female; Humans; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species | 2013 |
Green tea polyphenol epigallocatechin-3-gallate inhibits TLR4 signaling through the 67-kDa laminin receptor on lipopolysaccharide-stimulated dendritic cells.
Topics: Animals; Camellia sinensis; Catechin; Cells, Cultured; Cytokines; Dendritic Cells; Inflammation; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Mice; NF-kappa B; Receptors, Laminin; Signal Transduction; Toll-Like Receptor 4; Up-Regulation | 2012 |
Green tea (-)epigallocatechin-3-gallate reverses oxidative stress and reduces acetylcholinesterase activity in a streptozotocin-induced model of dementia.
Topics: Acetylcholinesterase; Animals; Antibiotics, Antineoplastic; Antioxidants; Catechin; Cognition; Dementia; Glial Fibrillary Acidic Protein; Glucose; Glutathione; Glutathione Peroxidase; Hippocampus; Injections, Intraventricular; Male; Maze Learning; Nerve Growth Factors; Neuroglia; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Space Perception; Streptozocin; Tea | 2013 |
Analysis of induction mechanisms of an insulin-inducible transcription factor SHARP-2 gene by (-)-epigallocatechin-3-gallate.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Catechin; Homeodomain Proteins; Insulin; NF-kappa B; Rats; Transcription Factor RelA; Up-Regulation | 2012 |
EGCG inhibits growth of human pancreatic tumors orthotopically implanted in Balb C nude mice through modulation of FKHRL1/FOXO3a and neuropilin.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Catechin; Cell Line, Tumor; Cell Proliferation; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Neuropilins; Pancreas; Pancreatic Neoplasms; Proliferating Cell Nuclear Antigen; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Catechins in neuroAIDS.
Topics: Animals; Anti-HIV Agents; Brain-Derived Neurotrophic Factor; Catechin; HIV Envelope Protein gp120; Humans; Mitochondria; Neuroprotective Agents; tat Gene Products, Human Immunodeficiency Virus | 2012 |
Neuroprotective effect of epigallocatechin-3-gallate against N-methyl-D-aspartate-induced excitotoxicity in the adult rat retina.
Topics: Animals; Apoptosis; Catechin; Cell Count; Cell Survival; Excitatory Amino Acid Agonists; Female; Injections, Intraperitoneal; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Wistar; Retinal Degeneration; Retinal Ganglion Cells; RNA, Messenger; Thy-1 Antigens | 2012 |
Better survival of random pattern skin flaps through the use of epigallocatechin gallate.
Topics: Angiogenesis Inducing Agents; Animals; Capillaries; Catechin; Dermatologic Surgical Procedures; Female; Graft Survival; Immunohistochemistry; Necrosis; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Surgical Flaps; Vascular Endothelial Growth Factor A | 2012 |
Screening of matrix metalloproteinase inhibitors by microanalysis with fluorescence detection.
Topics: Amino Acid Sequence; Catechin; Drug Evaluation, Preclinical; Electrophoresis, Microchip; Fluorescence; Humans; Inhibitory Concentration 50; Kinetics; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Molecular Sequence Data; Oleic Acid; Online Systems | 2013 |
Incompatibility between propericiazine oral solution and tea-based drink.
Topics: Administration, Oral; Antipsychotic Agents; Catechin; Phenothiazines; Tea | 2012 |
Epigallocatechin gallate affects survival and metabolism of human sperm.
Topics: Catechin; Cell Survival; Cholesterol; Dose-Response Relationship, Drug; Estradiol; Fulvestrant; Glucose; Humans; Lipid Metabolism; Male; Phosphorylation; Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Receptors, Estrogen; Sperm Motility; Spermatozoa; src-Family Kinases; Tea; Triglycerides; Tyrosine | 2012 |
Topical treatment with anti-oxidants and Au nanoparticles promote healing of diabetic wound through receptor for advance glycation end-products.
Topics: Administration, Topical; Animals; Antioxidants; Catechin; Cell Line; Diabetes Mellitus, Experimental; Fibroblasts; Glycation End Products, Advanced; Gold; Humans; Male; Metal Nanoparticles; Mice; Mice, Inbred BALB C; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Thioctic Acid; Wound Healing | 2012 |
[Integrated pharmacokinetic study of multiple effective components of tea polyphenols and its correlation with anti-free radical pharmacodynamics in rats].
Topics: Animals; Antioxidants; Area Under Curve; Catechin; Chromatography, Liquid; Free Radical Scavengers; Free Radicals; Injections, Intravenous; Lipid Peroxidation; Male; Mice; Polyphenols; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Tea | 2012 |
Alternative pathways of human islet amyloid polypeptide aggregation distinguished by (19)f nuclear magnetic resonance-detected kinetics of monomer consumption.
Topics: Benzothiazoles; Catechin; Circular Dichroism; Fluorine; Humans; Islet Amyloid Polypeptide; Kinetics; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Spectrometry, Fluorescence; Thiazoles | 2012 |
Epigallocatechin gallate as a modulator of Campylobacter resistance to macrolide antibiotics.
Topics: Animals; Anti-Bacterial Agents; Biological Transport, Active; Campylobacter; Campylobacter Infections; Catechin; Drug Resistance, Bacterial; Humans; Macrolides; Membrane Transport Proteins | 2012 |
[Protective effect of epigallocatechin-3-gallate on apoptosis of rat cerebellar granule neurons induced by acrylamide].
Topics: Acrylamide; Animals; Apoptosis; Catechin; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Female; Male; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2012 |
Gallated form of tea catechin, not nongallated form, increases fecal starch excretion in rats.
Topics: alpha-Amylases; Animals; Catechin; Dietary Carbohydrates; Feces; Intestinal Mucosa; Intestines; Male; Rats; Rats, Wistar; Starch; Statistics, Nonparametric; Tea | 2012 |
Mechanisms for epigallocatechin gallate induced inhibition of drug metabolizing enzymes in rat liver microsomes.
Topics: Animals; Antioxidants; Blotting, Western; Catechin; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytosol; Dose-Response Relationship, Drug; Drug Antagonism; Enzyme Inhibitors; Glutathione; Glutathione Transferase; Male; Microsomes, Liver; Protein Binding; Rats; Rats, Sprague-Dawley | 2012 |
Expression of NSAID-activated gene-1 by EGCG in head and neck cancer: involvement of ATM-dependent p53 expression.
Topics: Anticarcinogenic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Growth Differentiation Factor 15; Head and Neck Neoplasms; Heterografts; Humans; RNA, Small Interfering; Squamous Cell Carcinoma of Head and Neck; Tumor Suppressor Protein p53 | 2013 |
Impact of protease inhibitors on dentin matrix degradation by collagenase.
Topics: Analysis of Variance; Animals; Bacterial Proteins; Cariostatic Agents; Catechin; Cattle; Chlorhexidine; Collagen; Collagenases; Dentin; Extracellular Matrix; Ferrous Compounds; Protease Inhibitors; Sodium Fluoride; Tooth Demineralization; Tooth Erosion | 2012 |
Comparison between single-cell cultures and tissue cultures as model systems for evaluating the modulation of gene expression by food bioactives.
Topics: Aorta, Abdominal; Aortic Aneurysm, Abdominal; Catechin; Cell Culture Techniques; Cholesterol, Dietary; Dietary Supplements; Elective Surgical Procedures; Fatty Acids, Omega-3; Genetic Variation; Hep G2 Cells; Humans; Models, Biological; Models, Genetic; Tissue Culture Techniques; Transcription, Genetic | 2013 |
(-)-Epigallocatechin-3-gallate protects against NO-induced ototoxicity through the regulation of caspase- 1, caspase-3, and NF-κB activation.
Topics: Animals; Apoptosis; Caspase 1; Caspase 3; Catechin; Enzyme Activation; Gene Expression Regulation; Hair Cells, Auditory; Membrane Potential, Mitochondrial; NF-kappa B; Nitric Oxide; Organ of Corti; Protective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction | 2012 |
A cellular lipidomic study on the Aβ-induced neurotoxicity and neuroprotective effects of EGCG by using UPLC/MS-based glycerolipids profiling and multivariate analysis.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Arachidonic Acid; Catechin; Glycerides; Lipid Metabolism; Multivariate Analysis; Neurons; Neuroprotective Agents; PC12 Cells; Peptide Fragments; Phosphatidylcholines; Phospholipases A2; Phospholipids; Principal Component Analysis; Rats | 2012 |
Oxidative stability of (-)-epigallocatechin gallate in the presence of thiols.
Topics: Catechin; Hydrogen-Ion Concentration; Oxidation-Reduction; Polyphenols; Sulfhydryl Compounds | 2012 |
Combination therapy with taurine, epigallocatechin gallate and genistein for protection against hepatic fibrosis induced by alcohol in rats.
Topics: Actins; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Catechin; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Ethanol; gamma-Glutamyltransferase; Genistein; Liver Cirrhosis; Peroxidase; Proto-Oncogene Proteins c-bcl-2; Rats; RNA, Messenger; Smad3 Protein; Taurine | 2012 |
Inhibition of starch digestion by the green tea polyphenol, (-)-epigallocatechin-3-gallate.
Topics: Administration, Oral; Amylases; Animals; Area Under Curve; Blood Glucose; Catechin; Dose-Response Relationship, Drug; Glucose Transporter Type 2; Intestine, Small; Male; Mice; Pancreatic alpha-Amylases; Postprandial Period; Sodium-Glucose Transporter 1; Starch; Tea | 2012 |
(-)-Epigallocatechin-3-gallate decreases the impairment in learning and memory in spontaneous hypertension rats.
Topics: Animals; Antioxidants; Blood Pressure; Catechin; Hippocampus; Hypertension; Learning Disabilities; Lipid Peroxidation; Male; Maze Learning; Memory Disorders; Motor Activity; Oxidative Stress; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Tea | 2012 |
Green tea polyphenols function as prooxidants to inhibit Pseudomonas aeruginosa and induce the expression of oxidative stress-related genes.
Topics: Anti-Bacterial Agents; Antioxidants; Bacterial Proteins; Catechin; DNA Restriction Enzymes; Hydrogen Peroxide; Hydrogen-Ion Concentration; Oxidative Stress; Plant Extracts; Polyphenols; Pseudomonas aeruginosa; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Serine Endopeptidases; Tea; Up-Regulation | 2013 |
(-)-Epigallocatechin-3-gallate induces non-apoptotic cell death in human cancer cells via ROS-mediated lysosomal membrane permeabilization.
Topics: Apoptosis; Blotting, Western; Catechin; Cell Survival; Hep G2 Cells; Humans; Intracellular Membranes; Lysosomes; Reactive Oxygen Species | 2012 |
Green tea epigallocatechin-3-gallate modulates differentiation of naïve CD4⁺ T cells into specific lineage effector cells.
Topics: Animals; Catechin; CD4-Positive T-Lymphocytes; Cell Differentiation; Female; Interleukin-6; Mice; Nuclear Receptor Subfamily 1, Group F, Member 3; Receptors, Interleukin; Receptors, Interleukin-6; Signal Transduction; STAT3 Transcription Factor; T-Lymphocytes, Regulatory; Tea; Th1 Cells; Th17 Cells; Th2 Cells | 2013 |
Involvement of microRNAs in epigallocatechin gallate-mediated UVB protection in human dermal fibroblasts.
Topics: Antioxidants; Biomarkers, Tumor; Catechin; Cells, Cultured; Dermis; Fibroblasts; Gene Expression Profiling; Humans; MicroRNAs; Mitogen-Activated Protein Kinases; Oligonucleotide Array Sequence Analysis; Phosphorylation; Radiation-Protective Agents; Ultraviolet Rays | 2013 |
Characterizing antiprion compounds based on their binding properties to prion proteins: implications as medical chaperones.
Topics: Amides; Aminopyridines; Animals; Binding Sites; Carbazoles; Catechin; Congo Red; Magnetic Resonance Spectroscopy; Mice; Molecular Chaperones; Molecular Structure; Nitriles; Pentosan Sulfuric Polyester; Piperidines; Prions; Protein Conformation; Quinacrine; Surface Plasmon Resonance | 2013 |
Natural therapies assessment for the treatment of endometriosis.
Topics: Angiogenesis Inhibitors; Animals; Antioxidants; Apoptosis; Catechin; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endometriosis; Endometrium; Female; Humans; Injections, Intraperitoneal; Intestinal Diseases; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Random Allocation; Resveratrol; Stilbenes | 2013 |
Green tea extract reverses endothelial dysfunction and reduces atherosclerosis progression in homozygous knockout low-density lipoprotein receptor mice.
Topics: Alanine Transaminase; Animals; Antioxidants; Aorta; Atherosclerosis; Biomarkers; Catechin; Chemokine CCL2; Disease Models, Animal; Endothelium, Vascular; Female; Inflammation; Lipoproteins, LDL; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Plant Extracts; Receptors, LDL; Tea; Triglycerides; Tumor Necrosis Factor-alpha | 2012 |
Epigallocatechin-3-gallate inhibits angiotensin II and interleukin-6-induced C-reactive protein production in macrophages.
Topics: Angiotensin II; Anti-Inflammatory Agents; C-Reactive Protein; Cardiovascular Diseases; Catechin; Cell Line, Tumor; Humans; Inflammation; Interleukin-6; Macrophages; Reactive Oxygen Species; RNA, Messenger; Tea; U937 Cells | 2012 |
Separation of epigallocatechin gallate from tea polyphenol by simulated moving bed chromatography.
Topics: Adsorption; Catechin; Chromatography, Liquid; Polyphenols; Tea | 2012 |
Synergistic effect of L-Carnosine and EGCG in the prevention of physiological brain aging.
Topics: Aging; Animals; Brain; Carnosine; Catechin; Cell Death; Drug Synergism; Female; Heme Oxygenase-1; HSP72 Heat-Shock Proteins; Humans; Oxidative Stress; Pregnancy; Rats; Rats, Wistar | 2013 |
Reno-protective effects of epigallocatechingallate in a small piglet model of extracorporeal circulation.
Topics: Animals; Apoptosis Inducing Factor; Blood Pressure; Cardiopulmonary Bypass; Catechin; Creatinine; Heart Rate; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney; Poly Adenosine Diphosphate Ribose; Protective Agents; Swine; Tyrosine; Urea | 2013 |
Hydroxylation of (-)-epigallocatechin-3-O-gallate at 3'', but not 4'', is essential for the PI3-kinase/Akt-dependent phosphorylation of endothelial NO synthase in endothelial cells and relaxation of coronary artery rings.
Topics: Animals; Camellia sinensis; Cardiovascular Diseases; Catechin; Coronary Vessels; Endothelial Cells; Humans; Hydroxylation; In Vitro Techniques; Molecular Structure; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphorylation; Plant Extracts; Proto-Oncogene Proteins c-akt; Swine; Vasodilation | 2013 |
Trout-skin gelatin-based edible films containing phenolic antioxidants: effect on physical properties and oxidative stability of cod-liver oil model food.
Topics: Animals; Antioxidants; Catechin; Cod Liver Oil; Food Handling; Food Packaging; Food Storage; Gelatin; Oxidation-Reduction; Oxygen; Phenols; Physical Phenomena; Skin; Tea; Trout; Water | 2012 |
Polyphenols extracted from black tea (Camellia sinensis) residue by hot-compressed water and their inhibitory effect on pancreatic lipase in vitro.
Topics: Biflavonoids; Caffeine; Catechin; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Food Handling; Gallic Acid; Hot Temperature; Inhibitory Concentration 50; Lipase; Mass Spectrometry; Plant Extracts; Polyphenols; Tea | 2012 |
Anti-inflammatory activity of lipophilic epigallocatechin gallate (EGCG) derivatives in LPS-stimulated murine macrophages.
Topics: Animals; Anti-Inflammatory Agents; Catechin; Cell Line; Cyclooxygenase 2; Gene Expression; Lipopolysaccharides; Macrophages; Mice; Molecular Structure; Nitric Oxide Synthase Type II | 2012 |
(-)-Epigallocatechin-3-gallate stimulates both AMP-activated protein kinase and nuclear factor-kappa B signaling pathways.
Topics: AMP-Activated Protein Kinases; Animals; Basic Helix-Loop-Helix Transcription Factors; Catechin; Cell Line, Tumor; NF-kappa B; Rats; Signal Transduction; Up-Regulation | 2012 |
Epigallocathechin gallate, polyphenol present in green tea, inhibits stem-like characteristics and epithelial-mesenchymal transition in nasopharyngeal cancer cell lines.
Topics: Antineoplastic Agents, Phytogenic; Camellia sinensis; Carcinoma; Catechin; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplastic Stem Cells; Phytotherapy; Plant Extracts; Polyphenols; Tea | 2012 |
Resveratrol attenuates L-DOPA-induced hydrogen peroxide toxicity in neuronal cells.
Topics: Antioxidants; Catechin; Cell Line, Tumor; Cell Survival; Drug Evaluation, Preclinical; Drug Interactions; Fibroblasts; Fluoresceins; Humans; Hydrogen Peroxide; Levodopa; Monoamine Oxidase; Nerve Tissue Proteins; Neuroblastoma; Neurons; Neuroprotective Agents; Oxidative Stress; Quercetin; Resveratrol; Stilbenes; Tyrosine; Tyrosine 3-Monooxygenase | 2012 |
Inhibitory effects of catechin derivatives on mammalian DNA polymerase and topoisomerase activities and mouse one-cell zygote development.
Topics: Animals; Apoptosis; Catechin; Cattle; DNA; DNA-Directed DNA Polymerase; Humans; Mice; Nucleic Acid Synthesis Inhibitors; Rats; Tea; Topoisomerase Inhibitors; Zygote | 2013 |
(-)-Epigallocatechin 3-gallate inhibits invasion by inducing the expression of Raf kinase inhibitor protein in AsPC‑1 human pancreatic adenocarcinoma cells through the modulation of histone deacetylase activity.
Topics: Adenocarcinoma; Apoptosis; Blotting, Western; Cadherins; Catechin; Cell Movement; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Histone Deacetylases; Humans; Matrix Metalloproteinase 2; Neoplasm Invasiveness; NF-kappa B; Pancreatic Neoplasms; Phosphatidylethanolamine Binding Protein; Phosphorylation; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured | 2013 |
High-dose sodium selenite toxicity cannot be prevented by the co-administration of pharmacological levels of epigallocatechin-3-gallate which in turn aggravates the toxicity.
Topics: Animals; Catechin; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Glutathione Transferase; Growth Disorders; Liver; Male; Mice; Oxidative Stress; Protective Agents; Selenium; Sodium Selenite; Tissue Distribution | 2013 |
Evaluation of Camellia sinensis catechins as a swine antimicrobial feed additive that does not cause antibiotic resistance.
Topics: Animals; Anti-Bacterial Agents; Camellia sinensis; Catechin; Drug Resistance, Bacterial; Food Additives; Humans; Microbial Sensitivity Tests; Plant Leaves; Pseudomonas aeruginosa; Staphylococcus aureus; Swine | 2013 |
Enzymatic and chemical interesterification of rice bran oil, sheaolein, and palm stearin and comparative study of their physicochemical properties.
Topics: Antioxidants; Calorimetry, Differential Scanning; Catalysis; Catechin; Chemical Phenomena; Chromatography, Gas; Crystallization; Esterification; Fatty Acids; Magnetic Resonance Spectroscopy; Margarine; Oleic Acids; Oxidation-Reduction; Palm Oil; Phytosterols; Plant Oils; Rice Bran Oil; Triglycerides; Volatile Organic Compounds | 2012 |
EGCG inhibits CTGF expression via blocking NF-κB activation in cardiac fibroblast.
Topics: Animals; Catechin; Cell Proliferation; Cells, Cultured; Collagen; Connective Tissue Growth Factor; Disease Models, Animal; Fibroblasts; Fibronectins; Fibrosis; Gene Expression Regulation, Neoplastic; Humans; Male; Myocardium; NF-kappa B; Plant Extracts; Rats; Rats, Sprague-Dawley; Tea | 2013 |
[EGCG regulates TGF-β1-induced epithelial mesenchymal transition in squamous cell carcinoma of head and neck].
Topics: Antigens, CD; Cadherins; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Head and Neck Neoplasms; Humans; Signal Transduction; Smad7 Protein; Squamous Cell Carcinoma of Head and Neck; Transforming Growth Factor beta1; Vimentin | 2012 |
Rapid cytotoxicity screening platform for amyloid inhibitors using a membrane-potential sensitive fluorescent probe.
Topics: alpha-Synuclein; Amyloid beta-Peptides; Antioxidants; Barbiturates; Biosensing Techniques; Catechin; Cell Line, Tumor; Cell Survival; Flavanones; Fluorescent Dyes; Humans; Isoxazoles; Peptide Fragments; Recombinant Proteins; Thiobarbiturates | 2013 |
Cholestatic effect of epigallocatechin gallate in rats is mediated via decreased expression of Mrp2.
Topics: Animals; ATP-Binding Cassette Transporters; Bile Acids and Salts; Catechin; Cholestasis; Cholestenones; Cholesterol 7-alpha-Hydroxylase; Down-Regulation; Ethinyl Estradiol; Female; Glutathione; Hepatocytes; Homeostasis; Ileum; Permeability; Rats; Rats, Wistar; Up-Regulation | 2013 |
AFM probing the mechanism of synergistic effects of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) with cefotaxime against extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli.
Topics: beta-Lactamases; Catechin; Cefotaxime; Drug Synergism; Escherichia coli; Microbial Sensitivity Tests; Microscopy, Atomic Force; Oxidative Stress; Tea; Time Factors | 2012 |
Epigallocatechin gallate acts synergistically in combination with cisplatin and designed trans-palladiums in ovarian cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ovarian Epithelial; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; DNA Adducts; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Palladium | 2012 |
[Effects of EGCG on the nasopharyngeal carcinoma cell line CNE-2 and the expression of related gene].
Topics: Apoptosis; bcl-2-Associated X Protein; Carcinoma; Caspase 3; Catechin; Cell Line, Tumor; Cell Proliferation; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Proto-Oncogene Proteins c-bcl-2 | 2012 |
(-)-Epigallocatechin-3-gallate induces apoptosis and inhibits invasion and migration of human cervical cancer cells.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Movement; Cell Proliferation; Cell Survival; Chromatin; DNA Fragmentation; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Signal Transduction; Tissue Inhibitor of Metalloproteinase-1 | 2012 |
Phenolic promiscuity in the cell nucleus--epigallocatechingallate (EGCG) and theaflavin-3,3'-digallate from green and black tea bind to model cell nuclear structures including histone proteins, double stranded DNA and telomeric quadruplex DNA.
Topics: Biflavonoids; Camellia sinensis; Catechin; Cell Nucleus Structures; Circular Dichroism; DNA; G-Quadruplexes; Gallic Acid; Histones; Humans; Kinetics; Mass Spectrometry; Plant Extracts; Polyphenols; Tea; Telomere | 2013 |
The upregulation of transglutaminase-2 by cyclosporin a in human gingival fibroblasts is augmented by oxidative stress.
Topics: Acetylcysteine; Adult; Antioxidants; Catechin; Cell Culture Techniques; Cells, Cultured; Chromones; Curcumin; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblasts; Flavonoids; Free Radical Scavengers; Gingiva; GTP-Binding Proteins; Humans; Imidazoles; Immunosuppressive Agents; Male; Morpholines; Oxidative Stress; Phosphoinositide-3 Kinase Inhibitors; Protease Inhibitors; Protein Glutamine gamma Glutamyltransferase 2; Pyridines; Reactive Oxygen Species; Transglutaminases; Up-Regulation | 2013 |
Neuroprotective effect of (-)-epigallocatechin-3-gallate in rats when administered pre- or post-traumatic brain injury.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Brain Edema; Brain Injuries; Catechin; Deoxyguanosine; Disease Models, Animal; DNA, Single-Stranded; Drug Administration Schedule; Glial Fibrillary Acidic Protein; Lipid Peroxidation; Male; Maze Learning; Neurons; Neuroprotective Agents; Phosphopyruvate Hydratase; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Time Factors | 2013 |
(-)-Epigallocatechin-3-gallate inhibition of Epstein-Barr virus spontaneous lytic infection involves ERK1/2 and PI3-K/Akt signaling in EBV-positive cells.
Topics: Antiviral Agents; Catechin; Cell Line, Tumor; Cell Survival; Chromones; DNA, Viral; Enzyme Activation; Epstein-Barr Virus Infections; Flavonoids; Herpesvirus 4, Human; Humans; Lymphoma; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Morpholines; Nasopharyngeal Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Viral Proteins; Virus Activation | 2013 |
Inhibition of herpes simplex virus type 1 with the modified green tea polyphenol palmitoyl-epigallocatechin gallate.
Topics: Animals; Antigens, Viral; Antiviral Agents; Catechin; Cell Proliferation; Cell Survival; Chlorocebus aethiops; Dose-Response Relationship, Drug; Gene Expression Regulation, Viral; Green Fluorescent Proteins; Herpes Simplex; Herpesvirus 1, Human; Microscopy, Fluorescence; Tea; Vero Cells; Viral Envelope Proteins; Viral Proteins | 2013 |
Polyphenols suppress hydrogen peroxide-induced oxidative stress in human bone-marrow derived mesenchymal stem cells.
Topics: Biphenyl Compounds; Bone Marrow Cells; Catalase; Catechin; Colony-Forming Units Assay; Curcumin; Cytoprotection; Cytosol; DNA Damage; Female; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Intracellular Space; Male; Mesenchymal Stem Cells; Middle Aged; Nitric Oxide; Oxidative Stress; Picrates; Polyphenols; S-Nitroso-N-Acetylpenicillamine | 2013 |
The influence of flavonoid compounds on the in vitro inhibition study of a human fibroblast collagenase catalytic domain expressed in E. coli.
Topics: Binding, Competitive; Catalysis; Catalytic Domain; Catechin; Collagenases; Dose-Response Relationship, Drug; Escherichia coli; Fibroblasts; Flavonoids; Gallic Acid; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Inhibitory Concentration 50; Matrix Metalloproteinase 1; Matrix Metalloproteinase Inhibitors; Models, Molecular; Molecular Structure; Protein Conformation; Recombinant Fusion Proteins; Structure-Activity Relationship; Substrate Specificity | 2013 |
(-)-Epigallocatechin-3-gallate inhibits voltage-gated proton currents in BV2 microglial cells.
Topics: Animals; Catechin; Cell Line; Dose-Response Relationship, Drug; Electric Conductivity; Ion Channels; Mice; Microglia; Neuroprotective Agents; Protons | 2013 |
Epigallocatechin-3-gallate up-regulates tumor suppressor gene expression via a reactive oxygen species-dependent down-regulation of UHRF1.
Topics: Apoptosis; Catechin; CCAAT-Enhancer-Binding Proteins; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p16; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Jurkat Cells; Nuclear Proteins; Promoter Regions, Genetic; Reactive Oxygen Species; Tumor Protein p73; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Vascular Endothelial Growth Factor A | 2013 |
Epigallocatechin Gallate (EGCG) is the most effective cancer chemopreventive polyphenol in green tea.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; HCT116 Cells; Humans; Models, Molecular; Molecular Structure; Polyphenols; Structure-Activity Relationship; Tea | 2012 |
Kinetic study of catechin stability: effects of pH, concentration, and temperature.
Topics: Catechin; Drug Stability; Food Preservation; Hydrogen-Ion Concentration; Kinetics; Solutions; Tea; Temperature | 2012 |
Inhibitory mechanism of pancreatic amyloid fibril formation: formation of the complex between tea catechins and the fragment of residues 22-27.
Topics: Amyloid; Catechin; Islet Amyloid Polypeptide; Kinetics; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Peptide Fragments; Tea | 2012 |
Neuroprotective potential of epigallo catechin-3-gallate in PC-12 cells.
Topics: Animals; Antioxidants; Apoptosis; Catechin; Membrane Potential, Mitochondrial; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Protein Carbonylation; Rats; Tumor Necrosis Factor-alpha | 2013 |
(-)-Epicatechin gallate prevents alkali-salt mediated fibrillogenesis of hen egg white lysozyme.
Topics: Alkalies; Animals; Benzothiazoles; Catechin; Chickens; Circular Dichroism; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kinetics; Microscopy, Fluorescence; Muramidase; Nephelometry and Turbidimetry; Protein Structure, Secondary; Salts; Thiazoles; Time Factors; Tryptophan | 2013 |
Polyphenols can inhibit furin in vitro as a result of the reactivity of their auto-oxidation products to proteins.
Topics: Animals; Antioxidants; Catechin; Detergents; Furin; Glutathione; Humans; Hydrogen Peroxide; Oxidation-Reduction; Polyphenols; Proprotein Convertases | 2013 |
Erythrocyte membrane transporters during human ageing: modulatory role of tea catechins.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Catechin; Erythrocyte Membrane; Female; Humans; Male; Membrane Transport Proteins; Middle Aged; Oxidative Stress; Tea; Young Adult | 2013 |
Synergetic downregulation of 67 kDa laminin receptor by the green tea (Camellia sinensis) secondary plant compound epigallocatechin gallate: a new gateway in metastasis prevention?
Topics: Animals; Camellia sinensis; Catechin; Cell Line; Down-Regulation; Humans; Neoplasm Metastasis; Neoplasms; Plant Extracts; Receptors, Laminin | 2012 |
Combining the chemotherapeutic effects of epigallocatechin 3-gallate with siRNA-mediated p53 knock-down results in synergic pro-apoptotic effects.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Combined Modality Therapy; Gene Silencing; HeLa Cells; Humans; RNA, Small Interfering; Transfection; Treatment Outcome; Tumor Suppressor Protein p53 | 2012 |
Preventive effects of epigallocatechin-3-O-gallate against replicative senescence associated with p53 acetylation in human dermal fibroblasts.
Topics: Acetylation; Animals; beta-Galactosidase; Catechin; Cell Cycle; Cell Death; Cell Proliferation; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Cytoprotection; Dermis; Fibroblasts; Fluorescein-5-isothiocyanate; Humans; Hydrogen Peroxide; Inhibitory Concentration 50; Microscopy, Fluorescence; Protective Agents; Rats; Sirtuin 1; Tumor Suppressor Protein p53 | 2012 |
Effects of green tea catechins on cytochrome P450 2B6, 2C8, 2C19, 2D6 and 3A activities in human liver and intestinal microsomes.
Topics: Aryl Hydrocarbon Hydroxylases; Catechin; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Inhibitory Concentration 50; Intestines; Kinetics; Microsomes; Microsomes, Liver; Plant Extracts | 2013 |
Surface plasmon resonance imaging of amyloid-β aggregation kinetics in the presence of epigallocatechin gallate and metals.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Catechin; Copper; Ferric Compounds; Humans; Ions; Kinetics; Metals; Microscopy, Electron, Transmission; Peptide Fragments; Surface Plasmon Resonance; Thiazoles; Zinc | 2013 |
Novel immunoregulatory properties of EGCG on reducing inflammation in EAE.
Topics: Animals; Antigen-Presenting Cells; Catechin; CD4-Positive T-Lymphocytes; Cell Differentiation; Encephalomyelitis, Autoimmune, Experimental; Male; Mice; Mice, Inbred C57BL; Multiple Sclerosis; STAT Transcription Factors; Th17 Cells | 2013 |
Proanthocyanidin oligomers isolated from Salacia reticulata leaves potently inhibit pancreatic lipase activity.
Topics: Catechin; Inhibitory Concentration 50; Lipase; Pancreas; Plant Leaves; Plant Stems; Polyphenols; Proanthocyanidins; Salacia; Tea | 2013 |
Epigallocatechin-3-gallate prevents oxidative phosphorylation deficit and promotes mitochondrial biogenesis in human cells from subjects with Down's syndrome.
Topics: Adenosine Triphosphate; Catechin; Cells, Cultured; Chromosomes, Human, Pair 21; Down Syndrome; Fibroblasts; Heat-Shock Proteins; Humans; Mitochondria; Oxidative Phosphorylation; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Reactive Oxygen Species; Signal Transduction; Sirtuin 1; Tea; Transcription Factors; Trisomy | 2013 |
(-)-Epigallocatechin-3-gallate inhibits human papillomavirus (HPV)-16 oncoprotein-induced angiogenesis in non-small cell lung cancer cells by targeting HIF-1α.
Topics: Angiogenesis Inhibitors; Animals; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Gene Expression; Human papillomavirus 16; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-8; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Oncogene Proteins; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Platelet Endothelial Cell Adhesion Molecule-1; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; Repressor Proteins; Signal Transduction; Transfection; Vascular Endothelial Growth Factor A | 2013 |
Comparative evaluation of different co-antioxidants on the photochemical- and functional-stability of epigallocatechin-3-gallate in topical creams exposed to simulated sunlight.
Topics: Antioxidants; Ascorbic Acid; Biphenyl Compounds; Butylated Hydroxytoluene; Catechin; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Stability; Emulsions; Free Radicals; Light; Oxidation-Reduction; Photolysis; Picrates; Skin Cream; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Thioctic Acid; Vitamin E | 2013 |
Bioactive peptides/chitosan nanoparticles enhance cellular antioxidant activity of (-)-epigallocatechin-3-gallate.
Topics: Antioxidants; Biological Availability; Capsules; Caseins; Catechin; Chitosan; Free Radicals; Hep G2 Cells; Humans; Nanocapsules; Peptide Fragments; Phosphopeptides | 2013 |
Therapeutic efficacy of epigallocatechin gallate-loaded nanoliposomes against burn wound infection by methicillin-resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Burns; Catechin; Kidney; Liposomes; Liver; Male; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Nanostructures; Skin; Spleen; Staphylococcal Infections; Wound Infection | 2013 |
Aggregation of the salivary proline-rich protein IB5 in the presence of the tannin EgCG.
Topics: Amino Acid Sequence; Binding Sites; Catechin; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Protein Multimerization; Protein Structure, Quaternary; Salivary Proline-Rich Proteins | 2013 |
Degradation kinetics of chlorogenic acid at various pH values and effects of ascorbic acid and epigallocatechin gallate on its stability under alkaline conditions.
Topics: Ascorbic Acid; Caffeic Acids; Catechin; Chlorogenic Acid; Drug Stability; Hydrogen-Ion Concentration; Kinetics; Quinic Acid | 2013 |
(-)-Epigallocatechin-3-gallate (EGCG) attenuates peripheral nerve degeneration in rat sciatic nerve crush injury.
Topics: Animals; Catechin; Crush Syndrome; Male; Microscopy, Electron, Transmission; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Sciatic Nerve; Transcription, Genetic | 2013 |
The anti-adipogenic effects of (-)epigallocatechin gallate are dependent on the WNT/β-catenin pathway.
Topics: 3T3-L1 Cells; Adipogenesis; Animals; beta Catenin; Catechin; Mice; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; Transcription Factors; Wnt Proteins | 2013 |
In vitro mechanism for downregulation of ER-α expression by epigallocatechin gallate in ER+/PR+ human breast cancer cells.
Topics: Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; Down-Regulation; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase 1; HSP90 Heat-Shock Proteins; Humans; Nuclear Receptor Co-Repressor 1; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; RNA Polymerase II; Signal Transduction; Tea | 2013 |
Alterations in the intestinal assimilation of oxidized PUFAs are ameliorated by a polyphenol-rich grape seed extract in an in vitro model and Caco-2 cells.
Topics: Animals; Antioxidants; Biological Availability; Caco-2 Cells; Catechin; Diet; Dietary Fats; Fatty Acids, Unsaturated; Fishes; Food Storage; Gastric Mucosa; Grape Seed Extract; Humans; Ileum; Intestinal Mucosa; Jejunum; Lipid Peroxidation; Oxidation-Reduction; Polyphenols; Reactive Oxygen Species; Seafood; Stomach; Vitis | 2013 |
Transport by OATP1B1 and OATP1B3 enhances the cytotoxicity of epigallocatechin 3-O-gallate and several quercetin derivatives.
Topics: Animals; Antineoplastic Agents; Catechin; CHO Cells; Cricetinae; Hepatocytes; Humans; Liver-Specific Organic Anion Transporter 1; Molecular Structure; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Quercetin; Solute Carrier Organic Anion Transporter Family Member 1B3 | 2013 |
Epigallocatechin gallate and sulforaphane combination treatment induce apoptosis in paclitaxel-resistant ovarian cancer cells through hTERT and Bcl-2 down-regulation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Catechin; Cell Cycle; Cell Proliferation; Down-Regulation; Drug Resistance, Neoplasm; Female; Humans; Isothiocyanates; Ovarian Neoplasms; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Sulfoxides; Telomerase; Thiocyanates; Tumor Cells, Cultured | 2013 |
EGCG inhibits recepteur d'origine nantais expression by suppressing Egr-1 in gastric cancer cells.
Topics: Animals; Catechin; Cell Line, Tumor; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Plant Extracts; Promoter Regions, Genetic; Receptor Protein-Tyrosine Kinases; RNA Interference; RNA, Small Interfering; Stomach Neoplasms; Tea; Tetradecanoylphorbol Acetate; Transcription, Genetic; Xenograft Model Antitumor Assays | 2013 |
Intrathecal epigallocatechin gallate treatment improves functional recovery after spinal cord injury by upregulating the expression of BDNF and GDNF.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain-Derived Neurotrophic Factor; Catechin; Female; Glial Cell Line-Derived Neurotrophic Factor; Motor Activity; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord; Spinal Cord Injuries | 2013 |
Interaction of members of the heat shock protein-70 family with the macrophage mannose receptor.
Topics: Amino Acid Sequence; Binding Sites; Blotting, Western; Catechin; Gene Expression; HEK293 Cells; HeLa Cells; HSP70 Heat-Shock Proteins; Humans; Immunoprecipitation; Lectins, C-Type; Macrophages; Mannose Receptor; Mannose-Binding Lectins; Mass Spectrometry; Microscopy, Confocal; Molecular Sequence Data; Plasmids; Protein Binding; Protein Interaction Domains and Motifs; Protein Transport; Receptors, Cell Surface; Transfection | 2013 |
67-kDa laminin receptor increases cGMP to induce cancer-selective apoptosis.
Topics: Animals; Apoptosis; Caspases; Catechin; Cell Line, Tumor; Cell Proliferation; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Female; Humans; Imidazoles; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Molecular Weight; Multiple Myeloma; Neoplasms; Phosphodiesterase 5 Inhibitors; Piperazines; Receptors, Laminin; Signal Transduction; Sulfones; Triazines; Vardenafil Dihydrochloride; Xenograft Model Antitumor Assays | 2013 |
Sensitization of TRAIL-induced apoptosis in human hepatocellular carcinoma HepG2 cells by phytochemicals.
Topics: Apoptosis; Carcinoma, Hepatocellular; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 3; Catechin; DNA Fragmentation; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Indoles; Inhibitory Concentration 50; Liver Neoplasms; Proto-Oncogene Proteins c-bcl-2; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand | 2013 |
The activity against Ehrlich's ascites tumors of doxorubicin contained in self assembled, cell receptor targeted nanoparticle with simultaneous oral delivery of the green tea polyphenol epigallocatechin-3-gallate.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Catechin; Doxorubicin; Magnetic Resonance Spectroscopy; Male; Mice; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Spectrophotometry, Ultraviolet; Tea | 2013 |
Therapeutic potential of EGCG on acute renal damage in a rat model of obstructive nephropathy.
Topics: Acute Kidney Injury; Animals; Antioxidants; Catechin; Disease Models, Animal; Glutathione; Glutathione Disulfide; Humans; Infusions, Parenteral; Kidney; Male; NF-E2-Related Factor 2; Oxidative Stress; Rats; Reactive Oxygen Species; Signal Transduction | 2013 |
Functional characterization of ferret CCL20 and CCR6 and identification of chemotactic inhibitors.
Topics: Amino Acid Sequence; Animals; Catechin; Chemokine CCL20; Chemotaxis; Cloning, Molecular; DNA, Complementary; Dogs; Ferrets; Mice; Molecular Sequence Data; Open Reading Frames; Phylogeny; Protein Binding; Receptors, CCR6; Sequence Alignment; Sequence Analysis, DNA; Viral Proteins | 2013 |
Changes in skeletal muscle proteolytic gene expression after prophylactic supplementation of EGCG and NAC and eccentric damage.
Topics: Acetylcysteine; Calpain; Catechin; Dietary Supplements; Double-Blind Method; Exercise; Gene Expression; Humans; Male; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Nontherapeutic Human Experimentation; SKP Cullin F-Box Protein Ligases; Tripartite Motif Proteins; Ubiquitin-Protein Ligases; Young Adult | 2013 |
Prion protein-mediated toxicity of amyloid-β oligomers requires lipid rafts and the transmembrane LRP1.
Topics: Amyloid beta-Peptides; Animals; Caspase 3; Catechin; Cell Line, Tumor; Cell Membrane; Hippocampus; Humans; Low Density Lipoprotein Receptor-Related Protein-1; Membrane Microdomains; Microscopy, Fluorescence; Neurons; Prions; Protein Binding; Proto-Oncogene Proteins c-fyn; Rats; Rats, Wistar; Resveratrol; RNA Interference; Stilbenes; Tea | 2013 |
Discrimination of α-amino acids using green tea flavonoid (-)-epigallocatechin gallate as a chiral solvating agent.
Topics: Amino Acids; Catechin; Flavonoids; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Solvents; Stereoisomerism; Tea | 2013 |
EGCG attenuates high glucose-induced endothelial cell inflammation by suppression of PKC and NF-κB signaling in human umbilical vein endothelial cells.
Topics: Blood Glucose; Catechin; Diabetes Complications; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Human Umbilical Vein Endothelial Cells; Humans; Immunoblotting; Inflammation; Molecular Structure; NF-kappa B; Protein Kinase C; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Vascular Cell Adhesion Molecule-1 | 2013 |
RETRACTED: Tea polyphenols enhance cisplatin chemosensitivity in cervical cancer cells via induction of apoptosis.
Topics: Analysis of Variance; Antineoplastic Agents; Apoptosis; Biflavonoids; Blotting, Western; Catechin; Cell Proliferation; Cisplatin; Drug Resistance, Neoplasm; Female; HeLa Cells; Humans; Immunohistochemistry; Membrane Potential, Mitochondrial; NF-kappa B; Polyphenols; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Tea; Uterine Cervical Neoplasms | 2013 |
Regulation of nodularin-induced apoptosis by epigallocatechin-3-gallate on fish lymphocytes in vitro.
Topics: Animals; Antioxidants; Apoptosis; Blotting, Western; Catechin; Cells, Cultured; Dose-Response Relationship, Drug; Female; Flow Cytometry; Goldfish; Lymphocytes; Male; Marine Toxins; Membrane Potential, Mitochondrial; Nodularia; Oxidative Stress; Peptides, Cyclic; Reactive Oxygen Species; Water Pollutants, Chemical | 2013 |
Cytoprotective effect of epigallocatechin-3-gallate against deoxynivalenol-induced toxicity through anti-oxidative and anti-inflammatory mechanisms in HT-29 cells.
Topics: Anti-Inflammatory Agents; Antioxidants; Apoptosis; Caspase 3; Catechin; Cyclooxygenase 2; Cytoprotection; Fusarium; HT29 Cells; Humans; NF-kappa B; Oxidative Stress; Polyphenols; Tea; Trichothecenes; Up-Regulation | 2013 |
Antioxidant and pro-oxidant activity of (-)-epigallocatechin-3-gallate in food emulsions: Influence of pH and phenolic concentration.
Topics: Antioxidants; Catechin; Emulsions; Hydrogen-Ion Concentration; Linseed Oil; Oxidants; Phenols; Thiobarbituric Acid Reactive Substances | 2013 |
Vitexin-2-O-xyloside, raphasatin and (-)-epigallocatechin-3-gallate synergistically affect cell growth and apoptosis of colon cancer cells.
Topics: Apigenin; Apoptosis; Caspase 3; Catechin; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Synergism; Humans; Isothiocyanates; Mitochondria; Reactive Oxygen Species | 2013 |
The green tea polyphenol (-)-epigallocatechin-3-gallate inhibits magnesium binding to the C-domain of cardiac troponin C.
Topics: Actomyosin; Animals; Anticarcinogenic Agents; Calcium; Calcium Signaling; Catechin; Chickens; Electrocardiography; Magnesium; Myocardial Contraction; Myocardium; Protein Binding; Protein Structure, Tertiary; Rats; Tea; Troponin C | 2013 |
TGF-β1-induced epithelial-mesenchymal transition and acetylation of Smad2 and Smad3 are negatively regulated by EGCG in human A549 lung cancer cells.
Topics: Acetylation; Anticarcinogenic Agents; Antigens, CD; Cadherins; Catechin; Cell Line, Tumor; Cell Movement; Cell Survival; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; p300-CBP Transcription Factors; Protein Binding; Protein Processing, Post-Translational; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta1; Vimentin | 2013 |
Insights into antiamyloidogenic properties of the green tea extract (-)-epigallocatechin-3-gallate toward metal-associated amyloid-β species.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Camellia sinensis; Catechin; Copper; Humans; Metals; Models, Molecular; Neuroprotective Agents; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Plant Extracts; Protein Binding; Protein Conformation; Protein Multimerization; Tandem Mass Spectrometry; Zinc | 2013 |
Green tea extract supplementation induces the lipolytic pathway, attenuates obesity, and reduces low-grade inflammation in mice fed a high-fat diet.
Topics: Adiponectin; Animals; Catechin; Chromatography, High Pressure Liquid; Diet, High-Fat; Enzyme-Linked Immunosorbent Assay; Interleukin-10; Lipolysis; Mice; Myeloid Differentiation Factor 88; Obesity; Tea; TNF Receptor-Associated Factor 6; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2013 |
Cyclooxygenase-1 and prostacyclin production by endothelial cells in the presence of mild oxidative stress.
Topics: Animals; Aorta, Thoracic; Catechin; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Endothelial Cells; Epoprostenol; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; In Vitro Techniques; Male; Oxidative Stress; Rats; Vasodilator Agents | 2013 |
Electroanalysis of the interaction between (-)-epigallocatechin-3-gallate (EGCG) and amyloid-β in the presence of copper.
Topics: Amyloid beta-Peptides; Catechin; Copper; Microscopy, Electron, Transmission; Protein Binding | 2013 |
Reduction of ferrylmyoglobin by theanine and green tea catechins. Importance of specific Acid catalysis.
Topics: Catalysis; Catechin; Chemical Phenomena; Gallic Acid; Glutamates; Hydrogen-Ion Concentration; Metmyoglobin; Oxidation-Reduction; Tea | 2013 |
Membranar effects exerted in vitro by polyphenols - quercetin, epigallocatechin gallate and curcumin - on HUVEC and Jurkat cells, relevant for diabetes mellitus.
Topics: Anisotropy; Antioxidants; Catechin; Cell Membrane; Cell Survival; Chemokine CCL2; Curcumin; Diabetes Mellitus; Human Umbilical Vein Endothelial Cells; Humans; Jurkat Cells; Lipid Peroxidation; Membrane Potentials; Quercetin | 2013 |
Storage stability and physical characteristics of tea-polyphenol-bearing nanoliposomes prepared with milk fat globule membrane phospholipids.
Topics: Animals; Catechin; Chromatography, High Pressure Liquid; Fats; Hydrogen-Ion Concentration; Liposomes; Membrane Lipids; Milk; Nanostructures; Phospholipids; Polyphenols; Tea; Ultrafiltration | 2013 |
Protective effects of a catechin-rich extract on the hippocampal formation and spatial memory in aging rats.
Topics: Age Factors; Animals; Catechin; Dendrites; Disease Models, Animal; Hippocampus; Lysosomes; Male; Malondialdehyde; Maze Learning; Memory Disorders; Microscopy, Electron, Transmission; Mitochondria; Neuroprotective Agents; Protein Carbonylation; Pyramidal Cells; Random Allocation; Rats; Rats, Wistar; Silver Staining; Space Perception | 2013 |
Epigallocatechin gallate promotes p53 accumulation and activity via the inhibition of MDM2-mediated p53 ubiquitination in human lung cancer cells.
Topics: Catechin; Cell Line; Cell Line, Tumor; Cell Nucleus; HEK293 Cells; Humans; Lung Neoplasms; Phosphorylation; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-mdm2; Tea; Transcription, Genetic; Tumor Suppressor Protein p53; Ubiquitination; Up-Regulation | 2013 |
Synergistic interactions of epigallocatechin gallate and oxytetracycline against various drug resistant Staphylococcus aureus strains in vitro.
Topics: Anti-Bacterial Agents; Catechin; Drug Resistance, Multiple, Bacterial; Drug Synergism; Erythromycin; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxytetracycline; Plant Leaves; Tea; Tetracycline; Tetracycline Resistance | 2013 |
Epigallocatechin gallate attenuated the activation of rat cardiac fibroblasts induced by angiotensin II via regulating β-arrestin1.
Topics: Angiotensin II; Animals; Arrestins; beta-Arrestins; Catechin; Cell Survival; Cells, Cultured; Collagen; Fibroblasts; GTP-Binding Protein alpha Subunits, Gq-G11; Myocardium; Protein Kinase C-delta; Rats; Receptor, Angiotensin, Type 1; RNA Interference; RNA, Small Interfering | 2013 |
Influence of the green tea leaf extract on neurotoxicity of aluminium chloride in rats.
Topics: Acetylcholinesterase; Aluminum Chloride; Aluminum Compounds; Alzheimer Disease; Animals; Avoidance Learning; Brain; CA1 Region, Hippocampal; Camellia sinensis; Catechin; Chlorides; Glutathione; Male; Neurotoxicity Syndromes; Oxidation-Reduction; Rats; Rats, Wistar; Superoxide Dismutase; Tea | 2014 |
(-)-Epigallocatechin-3-gallate improves bone microarchitecture in ovariectomized rats.
Topics: Animals; Body Weight; Bone and Bones; Bone Density; Bone Diseases, Metabolic; Bone Morphogenetic Protein 2; Catechin; Female; Lumbar Vertebrae; Ovariectomy; Rats; Rats, Sprague-Dawley; Tibia | 2013 |
Epigallocatechin-3-gallate inhibits collagen production of nasal polyp-derived fibroblasts.
Topics: Actins; Adult; Antioxidants; Catechin; Cell Differentiation; Cells, Cultured; Collagen Type I; Extracellular Matrix; Female; Fibroblasts; Humans; Male; Myofibroblasts; Nasal Polyps; Reactive Oxygen Species; Transforming Growth Factor beta1 | 2014 |
Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Catechin; Cyclooxygenase 2; Diet, High-Fat; Down-Regulation; Fatty Liver; Female; Fibrosis; Forkhead Transcription Factors; Inflammation; Liver; Matrix Metalloproteinase 2; Nerve Tissue Proteins; NF-kappa B; Nitric Oxide Synthase Type II; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Tumor Necrosis Factor-alpha | 2014 |
The green tea catechin epigallocatechin gallate (EGCG) blocks cell motility, chemotaxis and development in Dictyostelium discoideum.
Topics: Catechin; Cell Movement; Chemotaxis; Cyclic AMP; Dictyostelium; Reverse Transcriptase Polymerase Chain Reaction | 2013 |
Phenotypic screening with oleaginous microalgae reveals modulators of lipid productivity.
Topics: Antioxidants; Batch Cell Culture Techniques; Biomass; Butylated Hydroxyanisole; Catechin; Colforsin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluorescent Dyes; Lipid Metabolism; Lipids; Microalgae; Oxazines; Phenotype; Quinacrine; Small Molecule Libraries | 2013 |
Quercetin and epigallocatechin-3-gallate effect on the anisotropy of model membranes with cholesterol.
Topics: 2-Naphthylamine; Catechin; Cell Membrane; Cholesterol; Dimyristoylphosphatidylcholine; Dose-Response Relationship, Drug; Fluorescent Dyes; Laurates; Liposomes; Phospholipids; Quercetin; Temperature | 2013 |
Preclinical demonstration of synergistic Active Nutrients/Drug (AND) combination as a potential treatment for malignant pleural mesothelioma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Catechin; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; Lung Neoplasms; Male; Mesothelioma; Mesothelioma, Malignant; Mice; Mice, Inbred NOD; Mice, SCID; Pleural Neoplasms; Signal Transduction; Xenograft Model Antitumor Assays | 2013 |
Molecular mechanism of the inhibition of EGCG on the Alzheimer Aβ(1-42) dimer.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Catechin; Circular Dichroism; Dimerization; Humans; Molecular Dynamics Simulation; Molecular Structure; Peptide Fragments; Thermodynamics | 2013 |
Epigallocatechin-3-gallate is a potent phytochemical inhibitor of intimal hyperplasia in the wire-injured carotid artery.
Topics: Animals; Cardiovascular Agents; Carotid Artery Injuries; Carotid Artery, Common; Carotid Intima-Media Thickness; Catechin; Cell Proliferation; Disease Models, Animal; Disulfides; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Hyperplasia; Injections, Intraperitoneal; Isothiocyanates; Male; Neointima; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Sulfinic Acids; Sulfoxides; Time Factors | 2013 |
Preparation of thyroid follicular cells for mRNA quantification after fluorescence-activated cell sorting.
Topics: Animals; Antibodies; Catechin; Cell Line; Flow Cytometry; Gene Expression; Humans; Nuclear Proteins; Rats; RNA Stability; RNA, Messenger; Thyroglobulin; Thyroid Gland; Thyroid Nuclear Factor 1; Transcription Factors | 2013 |
Epigallocatechin gallate targeting of membrane type 1 matrix metalloproteinase-mediated Src and Janus kinase/signal transducers and activators of transcription 3 signaling inhibits transcription of colony-stimulating factors 2 and 3 in mesenchymal stromal
Topics: Angiogenesis Inhibitors; Catechin; Cells, Cultured; Concanavalin A; Gene Silencing; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Janus Kinases; Macrophage Colony-Stimulating Factor; Matrix Metalloproteinase 14; Mesenchymal Stem Cells; Phosphorylation; Protein Processing, Post-Translational; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Toll-Like Receptor 2; Toll-Like Receptor 6; Transcription, Genetic | 2013 |
Green tea formulations with vitamin C and xylitol on enhanced intestinal transport of green tea catechins.
Topics: Antioxidants; Ascorbic Acid; Biological Availability; Caco-2 Cells; Catechin; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Humans; Intestinal Absorption; Intestinal Mucosa; Intestines; Mass Spectrometry; Plant Extracts; Tea; Xylitol | 2013 |
Epigallocatechin gallate inhibits growth and epithelial-to-mesenchymal transition in human thyroid carcinoma cell lines.
Topics: Actins; Apoptosis; Cadherins; Catechin; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; Epithelial-Mesenchymal Transition; Homeodomain Proteins; Humans; Integrin alpha5; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Nuclear Proteins; Proto-Oncogene Proteins c-akt; Thyroid Neoplasms; Transcription Factors; Tumor Suppressor Protein p53; Twist-Related Protein 1; Up-Regulation; Vimentin; Zinc Finger E-box-Binding Homeobox 1 | 2013 |
AMPK synergizes with the combined treatment of 1'-acetoxychavicol acetate and sodium butyrate to upregulate phase II detoxifying enzyme activities.
Topics: AMP-Activated Protein Kinases; Animals; Benzyl Alcohols; Butyric Acid; Catechin; Cells, Cultured; Drug Synergism; Epithelial Cells; Glutathione S-Transferase pi; Metabolic Detoxication, Phase II; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Phosphorylation; Rats; RNA, Messenger; Tumor Suppressor Protein p53; Up-Regulation; Xenobiotics | 2013 |
Effect of the flavonoid epigallocatechin-3-gallate on resin-dentin bond strength.
Topics: Acid Etching, Dental; Adhesiveness; Antioxidants; Catechin; Chlorhexidine; Composite Resins; Dental Bonding; Dental Cements; Dental Stress Analysis; Dentin; Humans; Materials Testing; Phosphoric Acids; Protease Inhibitors; Stress, Mechanical; Temperature; Tensile Strength; Time Factors; Water | 2013 |
Mechanisms of saccharide protection against epigallocatechin-3-gallate deterioration in aqueous solutions.
Topics: Antioxidants; Beverages; Carbohydrates; Catechin; Food Technology; Kinetics; Lactoglobulins | 2013 |
Catalase is inhibited by flavonoids.
Topics: Animals; Catalase; Catechin; Cattle; Enzyme Inhibitors; Flavonoids; Hydrogen Bonding; Hydrogen Peroxide; Hydrophobic and Hydrophilic Interactions; Liver | 2013 |
Epigallocatechin 3-gallate inhibits 7-ketocholesterol-induced monocyte-endothelial cell adhesion.
Topics: Acetylcysteine; Arteriosclerosis; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Catechin; Cell Adhesion; Endothelial Cells; Enzyme Inhibitors; Humans; Intercellular Adhesion Molecule-1; Ketocholesterols; Lipoproteins, HDL; Monocytes; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; U937 Cells | 2013 |
Inhibition of attachment of oral bacteria to immortalized human gingival fibroblasts (HGF-1) by tea extracts and tea components.
Topics: Actinomyces; Administration, Oral; Bacterial Adhesion; Catechin; Cells, Cultured; Fibroblasts; Flavonoids; Gallic Acid; Gingiva; Humans; Phenol; Plant Extracts; Stem Cells; Streptococcus; Streptococcus mitis; Streptococcus mutans; Tannins; Tea | 2013 |
Two new monoterpene glycosides from Qing Shan Lu Shui tea with inhibitory effects on leukocyte-type 12-lipoxygenase activity.
Topics: Animals; Arachidonate 12-Lipoxygenase; Catechin; Glycosides; Leukocytes; Lipoxygenase Inhibitors; Monoterpenes; Swine; Tea | 2013 |
The effect of orally administered epigallocatechin-3-gallate on ligature-induced periodontitis in rats.
Topics: Acid Phosphatase; Alveolar Bone Loss; Alveolar Process; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Catechin; Collagen; Down-Regulation; Epithelial Attachment; Immunohistochemistry; Interleukin-6; Isoenzymes; Male; Osteoclasts; Periodontitis; Random Allocation; Rats; Rats, Sprague-Dawley; Tartrate-Resistant Acid Phosphatase; Time Factors; Tooth Cervix; Tumor Necrosis Factor-alpha | 2013 |
Evaluation of unsaturated alkanoic acid amides as maskers of epigallocatechin gallate astringency.
Topics: Amides; Beverages; Catechin; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Grape Seed Extract; Humans; Polyunsaturated Alkamides; Reproducibility of Results; Salivation; Structure-Activity Relationship; Taste; Tea | 2013 |
Study of Abl1 tyrosine kinase inhibitors by liquid chromatography-electrospray ionization-mass spectrometry.
Topics: Amino Acid Sequence; Benzamides; Biological Products; Caffeic Acids; Catechin; Chromatography, Liquid; Drug Discovery; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Limit of Detection; Peptides; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Spectrometry, Mass, Electrospray Ionization | 2013 |
Anticancer activities of (-)-epigallocatechin-3-gallate encapsulated nanoliposomes in MCF7 breast cancer cells.
Topics: Anticarcinogenic Agents; Apoptosis; Breast Neoplasms; Catechin; Cell Proliferation; Cell Survival; Chitosan; Female; Humans; Liposomes; MCF-7 Cells; Nanoconjugates | 2013 |
Curcumin inhibits TGFβ1-induced CCN2 via Src, JNK, and Smad3 in gingiva.
Topics: Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Cell Culture Techniques; Cell Movement; Cells, Cultured; Connective Tissue Growth Factor; Curcumin; Enzyme Inhibitors; Fibroblasts; Flavonoids; Gingiva; Gingival Overgrowth; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Lovastatin; MAP Kinase Kinase 4; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Signal Transduction; Smad3 Protein; src-Family Kinases; Transforming Growth Factor beta1 | 2013 |
Toward the molecular mechanism(s) by which EGCG treatment remodels mature amyloid fibrils.
Topics: Amyloid; Catechin; HEK293 Cells; Humans; Models, Molecular; Molecular Structure | 2013 |
Epigallocatechin-3-gallate promotes apoptosis and expression of the caspase 9a splice variant in PC3 prostate cancer cells.
Topics: Apoptosis; Caspase 9; Catechin; Cell Line, Tumor; Cisplatin; Gene Expression Regulation, Neoplastic; Humans; Male; Prostatic Neoplasms; Protein Isoforms | 2013 |
Green tea epigallocatechin-3-gallate attenuates Porphyromonas gingivalis-induced atherosclerosis.
Topics: Animals; Anti-Inflammatory Agents; Aorta; Atherosclerosis; Bacteroidaceae Infections; Biomarkers; Catechin; Disease Models, Animal; Gene Expression Profiling; Male; Mice; Mice, Knockout; Porphyromonas gingivalis; Tea Tree Oil; Treatment Outcome | 2013 |
Green tea extract with polyethylene glycol-3350 reduces body weight and improves glucose tolerance in db/db and high-fat diet mice.
Topics: Adiponectin; Adipose Tissue; Animals; Anti-Obesity Agents; Caco-2 Cells; Camellia sinensis; Catechin; Diabetes Mellitus, Type 2; Diet, High-Fat; Glucose; Glucose Intolerance; Humans; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Obesity; Organ Size; Plant Extracts; Polyethylene Glycols; Retinol-Binding Proteins, Plasma | 2013 |
[Research on EGCG improving the degenerative changes of the brain in AD model mice induced with chemical drugs].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Catechin; Disease Models, Animal; Female; Galactose; Gene Expression Regulation; Hippocampus; Mice; Neurons; Neuroprotective Agents; Phytotherapy; Tea | 2012 |
Bioavailability of antioxidants applied to stratified human corneal epithelial cells.
Topics: Amidines; Antioxidants; Biological Availability; Catechin; Cells, Cultured; Epithelium, Corneal; Fluoresceins; Humans; Hypoxanthine; Limbus Corneae; Oxidants; Quercetin; Reactive Oxygen Species; Tissue Distribution; Xanthine Oxidase | 2013 |
Correlation between catechin content and NF-κB inhibition by infusions of green and black tea.
Topics: Caffeine; Camellia sinensis; Catechin; Cells, Cultured; Chromatography, High Pressure Liquid; Epithelial Cells; Free Radical Scavengers; Gene Expression Regulation; Humans; NF-kappa B; Tea; Transcription, Genetic | 2013 |
Effect of emulsification on the skin permeation and UV protection of catechin.
Topics: Animals; Catechin; Cell Line; Cell Survival; Emulsions; Humans; Keratinocytes; Male; Permeability; Rats; Skin; Solutions; Ultraviolet Rays | 2014 |
Epigallocatechin-3-Gallate (EGCG) inhibits cell proliferation and migratory behaviour of triple negative breast cancer cells.
Topics: Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Neoplasm Proteins | 2013 |
The effects of ErhBMP-2-/EGCG-coated BCP bone substitute on dehiscence around dental implants in dogs.
Topics: Animals; Bone Morphogenetic Protein 2; Bone Substitutes; Catechin; Dental Implants; Dental Prosthesis Design; Dogs; Guided Tissue Regeneration, Periodontal; Hydroxyapatites; Osteogenesis; Recombinant Proteins; Titanium; Transforming Growth Factor beta | 2014 |
(-)-Epigallocatechin-3-gallate alleviates spatial memory impairment in APP/PS1 mice by restoring IRS-1 signaling defects in the hippocampus.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Blotting, Western; Catechin; Disease Models, Animal; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Immunohistochemistry; Insulin Receptor Substrate Proteins; JNK Mitogen-Activated Protein Kinases; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Peptide Fragments; Phosphorylation; Presenilin-1; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Tumor Necrosis Factor-alpha | 2013 |
(-)-Epigallocatechin-3-gallate, a potential inhibitor to human dicarbonyl/L-xylulose reductase.
Topics: Catalytic Domain; Catechin; Enzyme Inhibitors; Escherichia coli; Gene Expression; Humans; Hydrogen Bonding; Molecular Docking Simulation; NADP; Recombinant Proteins; Sugar Alcohol Dehydrogenases; Surface Plasmon Resonance | 2013 |
Quercetin and epigallocatechin gallate inhibit glucose uptake and metabolism by breast cancer cells by an estrogen receptor-independent mechanism.
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Catechin; Cell Death; Cell Proliferation; Female; Glucose; Humans; Lactic Acid; MCF-7 Cells; Quercetin; Receptors, Estrogen | 2013 |
Epigallocatechin gallate protects against nitric oxide-induced apoptosis via scavenging ROS and modulating the Bcl-2 family in human dental pulp cells.
Topics: Apoptosis; Catechin; Cell Survival; Cells, Cultured; Dental Pulp; Free Radical Scavengers; Humans; Multigene Family; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species | 2013 |
Polyphenols protect the epithelial barrier function of Caco-2 cells exposed to indomethacin through the modulation of occludin and zonula occludens-1 expression.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Caco-2 Cells; Catechin; Enterocytes; Functional Food; Gene Expression Regulation; Humans; Indomethacin; Occludin; Permeability; Polyphenols; Protein Transport; Quercetin; Resveratrol; Stilbenes; Tight Junctions; Zonula Occludens-1 Protein | 2013 |
Green tea catechins can bind and modify ERp57/PDIA3 activity.
Topics: Catalytic Domain; Catechin; DNA; Enzyme Assays; Humans; Kinetics; Ligands; Models, Molecular; Oxidation-Reduction; Protein Binding; Protein Disulfide-Isomerases; Protein Structure, Tertiary; Recombinant Proteins; Spectrometry, Fluorescence; Structure-Activity Relationship; Surface Plasmon Resonance | 2013 |
Effect of epigallocatechin-3-gallate on graft-versus-host disease.
Topics: Animals; Catechin; DNA (Cytosine-5-)-Methyltransferases; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Interleukin Receptor Common gamma Subunit; Leukocytes, Mononuclear; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; STAT1 Transcription Factor; Transplantation, Heterologous; Transplantation, Homologous | 2014 |
Transcriptional activation of flavan-3-ols biosynthesis in grape berries by UV irradiation depending on developmental stage.
Topics: Analysis of Variance; Anthocyanins; Biosynthetic Pathways; Catechin; Flavonoids; Fruit; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Genes, Plant; Plant Proteins; Real-Time Polymerase Chain Reaction; Time Factors; Transcriptional Activation; Ultraviolet Rays; Vitis | 2013 |
Nodulisporisteriods A and B, the first 3,4-seco-4-methyl-progesteroids from Nodulisporium sp.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Androstenes; Catechin; Crystallography, X-Ray; Drug Evaluation, Preclinical; Humans; Lactones; Models, Molecular; Molecular Conformation; Peptide Fragments; Propionates; Protein Multimerization; Secosteroids; Xylariales | 2013 |
Epigallocatechin-3-gallate reduces myometrial infiltration, uterine hyperactivity, and stress levels and alleviates generalized hyperalgesia in mice induced with adenomyosis.
Topics: Adenomyosis; Animals; Biomarkers; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hydrocortisone; Hyperalgesia; Mice; Mice, Inbred ICR; Myometrium; Pain Threshold; Reaction Time; Stress, Physiological; Tamoxifen; Time Factors; Uterine Contraction | 2013 |
Histone deacetylase inhibition by Japanese encephalitis virus in monocyte/macrophages: a novel viral immune evasion strategy.
Topics: Animals; Antigen Presentation; Catechin; Cell Line; Encephalitis; Encephalitis Virus, Japanese; Histone Deacetylases; Histones; Host-Pathogen Interactions; Humans; Immune Evasion; Immunity, Innate; Inflammation Mediators; Interferons; Macrophages; Mice | 2013 |
Epigallocatechin-3 gallate inhibits cancer invasion by repressing functional invadopodia formation in oral squamous cell carcinoma.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Catechin; Cell Membrane; Cell Movement; Cell Proliferation; Cortactin; Extracellular Matrix; Focal Adhesion Kinase 1; Gene Expression Regulation, Neoplastic; Humans; Male; Matrix Metalloproteinases; Mice; Mice, Inbred BALB C; Mouth Neoplasms; Neoplasm Invasiveness; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); rhoA GTP-Binding Protein; Xenograft Model Antitumor Assays | 2013 |
PI3K/AKT/mTOR signaling is involved in (-)-epigallocatechin-3-gallate-induced apoptosis of human pancreatic carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Camellia sinensis; Catechin; Cell Line, Tumor; Cell Proliferation; Humans; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinase; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; RNA, Messenger; Signal Transduction; TOR Serine-Threonine Kinases; Up-Regulation | 2013 |
Synthesis of PLGA nanoparticles of tea polyphenols and their strong in vivo protective effect against chemically induced DNA damage.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Biflavonoids; Catechin; DNA Damage; DNA Repair; Female; Gene Expression Regulation; Lactic Acid; Mice; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Skin; Tea | 2013 |
Treatment with EGCG in NSCLC leads to decreasing interstitial fluid pressure and hypoxia to improve chemotherapy efficacy through rebalance of Ang-1 and Ang-2.
Topics: Angiogenesis Inhibitors; Angiopoietin-1; Angiopoietin-2; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Catechin; Chemotherapy, Adjuvant; Cisplatin; Drug Therapy, Combination; Extracellular Fluid; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Oxygen | 2013 |
Crystal engineering of green tea epigallocatechin-3-gallate (EGCg) cocrystals and pharmacokinetic modulation in rats.
Topics: Animals; Calorimetry, Differential Scanning; Catechin; Rats; Solubility; Spectroscopy, Fourier Transform Infrared; Tea; Thermogravimetry; X-Ray Diffraction | 2013 |
Combination of low concentration of (-)-epigallocatechin gallate (EGCG) and curcumin strongly suppresses the growth of non-small cell lung cancer in vitro and in vivo through causing cell cycle arrest.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Clone Cells; Curcumin; Cyclin B1; Cyclin D1; DNA Replication; Female; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude | 2013 |
Epigallocatechin gallate (EGCG) stimulates autophagy in vascular endothelial cells: a potential role for reducing lipid accumulation.
Topics: Adenylate Kinase; Animals; Autophagy; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Catechin; Cattle; Cells, Cultured; DNA Primers; Endothelium, Vascular; Lipid Metabolism | 2013 |
Depolymerization of cranberry procyanidins using (+)-catechin, (-)-epicatechin, and (-)-epigallocatechin gallate as chain breakers.
Topics: Catechin; Plant Extracts; Polymerization; Proanthocyanidins; Vaccinium macrocarpon | 2013 |
Antioxidant enzymes mediate survival of breast cancer cells deprived of extracellular matrix.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Ascorbic Acid; Blotting, Western; Breast Neoplasms; Catalase; Catechin; Cell Adhesion; Cell Line; Cell Line, Tumor; Cell Survival; Chromans; Extracellular Matrix; Female; Humans; Mice; Mice, Nude; Reactive Oxygen Species; RNA Interference; Superoxide Dismutase; Tomography, X-Ray Computed; Xenograft Model Antitumor Assays | 2013 |
Inhibitory effect of catechin-related compounds on renin activity.
Topics: Antihypertensive Agents; Catechin; Enzyme Assays; Gallic Acid; Humans; Recombinant Proteins; Renin; Solutions; Structure-Activity Relationship; Tea | 2013 |
Pin1 inhibitors: Pitfalls, progress and cellular pharmacology.
Topics: Animals; Binding Sites; Catalytic Domain; Catechin; Drug Design; Enzyme Inhibitors; Humans; Mice; NIMA-Interacting Peptidylprolyl Isomerase; Peptides; Peptidylprolyl Isomerase; Piperidines; Protein Binding; Small Molecule Libraries; Thiram | 2013 |
[Effect of EGCG on the proliferation and invasion of human hepatoma HepG2 cells].
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Proliferation; Hep G2 Cells; Humans; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Sincalide; Vascular Endothelial Growth Factor A | 2013 |
Inducing apoptosis of cancer cells using small-molecule plant compounds that bind to GRP78.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biphenyl Compounds; Catechin; Cell Line, Tumor; Cell Survival; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Humans; Lignans; Molecular Targeted Therapy; Molecular Weight; Neoplasms; Protein Binding | 2013 |
Involvement of α7 nAChR signaling cascade in epigallocatechin gallate suppression of β-amyloid-induced apoptotic cortical neuronal insults.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Catechin; Cell Survival; Cells, Cultured; Cerebral Cortex; Neurons; Neuroprotective Agents; Peptide Fragments; Rats; Signal Transduction | 2014 |
Green tea catechins based functional drink (Green cool) improves the antioxidant status of SD rats fed on high cholesterol and sucrose diets.
Topics: Animals; Antioxidants; Beverages; Catechin; Cholesterol, Dietary; Dietary Sucrose; Glutathione; Rats; Rats, Sprague-Dawley; Sensation; Tea | 2013 |
Effect of epigallocatechin-3-gallate on inflammatory mediators release in LPS-induced Parkinson's disease in rats.
Topics: Animals; Catechin; Dopamine; Inflammation Mediators; Lipopolysaccharides; Male; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley | 2013 |
Protonation of epigallocatechin-3-gallate (EGCG) results in massive aggregation and reduced oral bioavailability of EGCG-dispersed selenium nanoparticles.
Topics: Animals; Biological Availability; Catechin; Chemistry, Pharmaceutical; Dietary Supplements; Drug Stability; Hydrogen-Ion Concentration; Kidney; Liver; Male; Mice; Nanoparticles; Particle Size; Selenium; Serum Albumin, Bovine | 2013 |
Epigallocatechin gallate effectively ameliorates fluoride-induced oxidative stress and DNA damage in the liver of rats.
Topics: Adenosine Triphosphatases; Animals; Antioxidants; Bilirubin; Biomarkers; Body Mass Index; Catechin; DNA Damage; Eating; Fluorides; Free Radical Scavengers; Hepatocytes; Lipid Peroxidation; Lipid Peroxides; Liver; Male; Oxidative Stress; Pilot Projects; Protein Carbonylation; Random Allocation; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2013 |
Anti-edema effect of epigallocatechin gallate on spinal cord injury in rats.
Topics: Animals; Aquaporin 4; Blotting, Western; Catechin; Disease Models, Animal; Edema; Glial Fibrillary Acidic Protein; Immunohistochemistry; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries | 2013 |
Synthesis and structure-activity relationships of EGCG analogues, a recently identified Hsp90 inhibitor.
Topics: Antineoplastic Agents; Catechin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HSP90 Heat-Shock Proteins; Humans; MCF-7 Cells; Molecular Structure; Structure-Activity Relationship | 2013 |
The phytochemical, EGCG, extends lifespan by reducing liver and kidney function damage and improving age-associated inflammation and oxidative stress in healthy rats.
Topics: Aging; Animals; Blood Glucose; Blood Pressure; Body Weight; Catechin; Feeding Behavior; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression Regulation; Heart Rate; Inflammation; Kidney; Kidney Function Tests; Lipids; Liver; Liver Function Tests; Longevity; Male; NF-kappa B; Oxidative Stress; Phytochemicals; Rats; Rats, Wistar; RNA, Messenger; Sirtuin 1 | 2013 |
(-)-Epigallocatechin-3-gallate blocks nicotine-induced matrix metalloproteinase-9 expression and invasiveness via suppression of NF-κB and AP-1 in endothelial cells.
Topics: Catechin; Endothelial Cells; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasm Metastasis; NF-kappa B; Nicotine; Reactive Oxygen Species; Transcription Factor AP-1 | 2013 |
Ex vivo evaluation of antifibrotic compounds in skin scarring: EGCG and silencing of PAI-1 independently inhibit growth and induce keloid shrinkage.
Topics: Adolescent; Adult; Apoptosis; Catechin; Cell Proliferation; Collagen; Dexamethasone; Gene Knockdown Techniques; Gene Silencing; Humans; Keloid; Organ Culture Techniques; Plasminogen Activator Inhibitor 1; RNA, Small Interfering; Skin; Young Adult | 2013 |
(-)-Epigallocatechin-3-gallate inhibits CC chemokine ligand 11 production in human gingival fibroblasts.
Topics: Anthracenes; Catechin; Cells, Cultured; Chemokine CCL11; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Gingiva; Humans; Imidazoles; Interleukin-1beta; Interleukin-4; JNK Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Signal Transduction; Th2 Cells; Tumor Necrosis Factor-alpha | 2013 |
Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cells.
Topics: Antineoplastic Agents; Catechin; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drug Screening Assays, Antitumor; Drug Synergism; fms-Like Tyrosine Kinase 3; Gene Expression; Gene Expression Regulation, Leukemic; HSP90 Heat-Shock Proteins; Humans; Infant; Leukemia, Myeloid, Acute; Male; Mitogen-Activated Protein Kinases; Mutagenesis, Insertional; Phosphorylation; Point Mutation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; STAT5 Transcription Factor; Staurosporine | 2013 |
(-)-Epigallocatechin gallate amplifies interleukin-1-stimulated interleukin-6 synthesis in osteoblast-like MC3T3-E1 cells.
Topics: AMP-Activated Protein Kinases; Animals; Catechin; Cell Line; Dose-Response Relationship, Drug; Drug Synergism; Gene Expression Regulation; I-kappa B Proteins; Interleukin-1; Interleukin-6; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; RNA, Messenger; Signal Transduction | 2013 |
Assessment of DNA damage and lipid peroxidation in diabetic mice: effects of propolis and epigallocatechin gallate (EGCG).
Topics: Animals; Antioxidants; Bees; Brain; Catechin; DNA Damage; Humans; Kidney; Lipid Peroxidation; Liver; Mice; Mice, Inbred NOD; Propolis | 2013 |
Anti-metastatic and differential effects on protein expression of epigallocatechin-3-gallate in HCCLM6 hepatocellular carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Catechin; Cell Differentiation; Cell Line, Tumor; Cell Survival; DNA Helicases; DNA-Binding Proteins; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; Liver Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Molecular Chaperones; Neoplasm Metastasis; Nuclear Proteins; Nucleophosmin; Protein Processing, Post-Translational; Proteomics; RNA-Binding Proteins | 2013 |
Epigallocatechin-3-gallate attenuates head and neck cancer stem cell traits through suppression of Notch pathway.
Topics: Animals; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Cell Proliferation; Female; Head and Neck Neoplasms; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Multidrug Resistance-Associated Protein 2; Neoplastic Stem Cells; Receptors, Notch; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; Transfection; Xenograft Model Antitumor Assays | 2013 |
Epigallocatechin-3-gallate regulates the expression of Kruppel-like factor 4 through myocyte enhancer factor 2A.
Topics: Apoptosis; Blotting, Western; Catechin; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; G1 Phase; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; MEF2 Transcription Factors; Phosphorylation; Promoter Regions, Genetic; Resting Phase, Cell Cycle; RNA, Messenger | 2014 |
Effect of green tea and its polyphenols on mouse liver.
Topics: Animals; Camellia sinensis; Catechin; Chemical and Drug Induced Liver Injury; Fever; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred Strains; Plant Extracts; Polyphenols; Tea | 2013 |
Enhancement of (-)-epigallocatechin-3-gallate and theaflavin-3-3'-digallate induced apoptosis by ascorbic acid in human lung adenocarcinoma SPC-A-1 cells and esophageal carcinoma Eca-109 cells via MAPK pathways.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Ascorbic Acid; Biflavonoids; Caspase 3; Caspase 9; Catechin; Cell Line, Tumor; Enzyme Inhibitors; Esophageal Neoplasms; Gallic Acid; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MAP Kinase Signaling System | 2013 |
Regulation of Id1 expression by epigallocatechin‑3‑gallate and its effect on the proliferation and apoptosis of poorly differentiated AGS gastric cancer cells.
Topics: Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Differentiation Protein 1; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Stomach Neoplasms | 2013 |
Epigallocatechin-3-gallate exerts protective effects against heat stress through modulating stress-responsive transcription factors in poultry.
Topics: Animal Feed; Animals; Antibodies; Antioxidants; Catechin; Chickens; Coturnix; Cyclooxygenase 2; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Female; Heat-Shock Proteins; Heat-Shock Response; Liver; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Transcription Factor AP-1 | 2013 |
Negative modulation of mitochondrial oxidative phosphorylation by epigallocatechin-3 gallate leads to growth arrest and apoptosis in human malignant pleural mesothelioma cells.
Topics: Adenosine Triphosphate; Apoptosis; Catalase; Catechin; Cell Cycle; Cell Proliferation; Cells, Cultured; Cytochromes c; Electron Transport Complex I; Electron Transport Complex II; Epithelial Cells; Humans; Immunoblotting; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Mitochondria; Mitochondrial Proton-Translocating ATPases; Oxidative Phosphorylation; Pleural Neoplasms; Reactive Oxygen Species; Superoxide Dismutase | 2013 |
Antibacterial and physical properties of EGCG-containing glass ionomer cements.
Topics: Anti-Bacterial Agents; Biofilms; Cariostatic Agents; Catechin; Chemical Phenomena; Chlorhexidine; Chromatography; Colorimetry; Coloring Agents; Dental Stress Analysis; Fluorides; Glass Ionomer Cements; Hardness; Humans; Light; Materials Testing; Microscopy, Electron, Scanning; Pliability; Spectrophotometry; Streptococcus mutans; Stress, Mechanical; Surface Properties; Tetrazolium Salts; Thiazoles | 2013 |
Epigallocatechin-3-gallate prevents heat shock-induced MMP-1 expression by inhibiting AP-1 activity in human dermal fibroblasts.
Topics: Aging, Premature; Animals; Catechin; Dermis; Fibroblasts; Gene Expression Regulation; Hot Temperature; Humans; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 1; Mice; NIH 3T3 Cells; Protein Binding; Signal Transduction; Skin Aging; Transcription Factor AP-1 | 2013 |
Interaction of characteristic structural elements of persimmon tannin with Chinese cobra PLA2.
Topics: Animals; Catechin; Diospyros; Elapid Venoms; Elapidae; Flavonoids; Fruit; Molecular Structure; Phospholipases A2 | 2013 |
Epigallocatechin-gallate (EGCG) regulates autophagy in human retinal pigment epithelial cells: a potential role for reducing UVB light-induced retinal damage.
Topics: Antioxidants; Autophagy; Catechin; Cell Line; Humans; Retinal Pigment Epithelium; Signal Transduction; TOR Serine-Threonine Kinases; Ultraviolet Rays | 2013 |
Phosphodiesterase 5 inhibitor acts as a potent agent sensitizing acute myeloid leukemia cells to 67-kDa laminin receptor-dependent apoptosis.
Topics: Apoptosis; Catechin; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Synergism; Enzyme Activation; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Nitric Oxide Synthase Type III; Oncogene Protein v-akt; Phosphodiesterase 5 Inhibitors; Primary Cell Culture; Receptors, Laminin; Signal Transduction; Sphingomyelin Phosphodiesterase | 2013 |
Effects of green tea extract and (-)-epigallocatechin-3-gallate on pharmacokinetics of nadolol in rats.
Topics: Animals; Area Under Curve; Camellia sinensis; Catechin; Herb-Drug Interactions; Intestinal Absorption; Male; Nadolol; Plant Extracts; Rats; Rats, Sprague-Dawley | 2013 |
(-)-Epigallocatechin gallate inhibits TNF-α-induced PAI-1 production in vascular endothelial cells.
Topics: Catechin; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Flavonoids; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Phosphorylation; Plaque, Atherosclerotic; Plasminogen Activator Inhibitor 1; Receptors, Tumor Necrosis Factor, Type I; Tea; Time Factors; Tumor Necrosis Factor-alpha | 2013 |
A computational exploration of the interactions of the green tea polyphenol (-)-Epigallocatechin 3-Gallate with cardiac muscle troponin C.
Topics: Binding Sites; Calcium; Catechin; Humans; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Myocardial Contraction; Myocardium; Polyphenols; Protein Binding; Protein Interaction Domains and Motifs; Tea; Troponin C | 2013 |
Aggregation modulators interfere with membrane interactions of β2-microglobulin fibrils.
Topics: beta 2-Microglobulin; Catechin; Cell Membrane; Heparin; Humans; Polymerization; Polyphenols; Protein Binding; Unilamellar Liposomes | 2013 |
Chemoprevention of skin cancer with 1,1-Bis (3'-indolyl)-1-(aromatic) methane analog through induction of the orphan nuclear receptor, NR4A2 (Nurr1).
Topics: 8-Hydroxy-2'-Deoxyguanosine; Apoptosis; Blotting, Western; Catechin; Cell Line, Tumor; Cell Survival; Cells, Cultured; Chemoprevention; Deoxyguanosine; Dose-Response Relationship, Drug; Humans; Immunohistochemistry; Indoles; Inhibitory Concentration 50; Keratinocytes; Nuclear Receptor Subfamily 4, Group A, Member 2; Oxidative Stress; Reactive Oxygen Species; Skin Neoplasms; Ultraviolet Rays | 2013 |
Inhibition of influenza virus internalization by (-)-epigallocatechin-3-gallate.
Topics: Animals; Antiviral Agents; Catechin; Cell Line; Enzyme Inhibitors; Humans; Neuraminidase; Orthomyxoviridae; Viral Proteins; Virus Internalization | 2013 |
Anti-cancer effects of naturally occurring compounds through modulation of signal transduction and miRNA expression in human colon cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, Neoplasm; Humans; MicroRNAs; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Resveratrol; Signal Transduction; Stilbenes; Xanthones | 2013 |
Characterization of binding interactions of (-)-epigallocatechin-3-gallate from green tea and lipase.
Topics: Animals; Camellia sinensis; Catechin; Hydrogen Bonding; Kinetics; Lipase; Models, Molecular; Plant Extracts; Protein Binding; Swine; Thermodynamics | 2013 |
Bi-layer composite dressing of gelatin nanofibrous mat and poly vinyl alcohol hydrogel for drug delivery and wound healing application: in-vitro and in-vivo studies.
Topics: Animals; Antioxidants; Bandages; Catechin; Delayed-Action Preparations; Equipment Design; Equipment Failure Analysis; Gelatin; Male; Materials Testing; Nanocapsules; Polyvinyl Alcohol; Rats; Rats, Wistar; Skin; Transdermal Patch; Treatment Outcome; Wound Healing; Wounds, Penetrating | 2013 |
Non-alcoholic steatohepatitis and preneoplastic lesions develop in the liver of obese and hypertensive rats: suppressing effects of EGCG on the development of liver lesions.
Topics: Angiotensin II; Animals; Anticarcinogenic Agents; Catechin; Fatty Liver; Gene Expression; Hypertension; Interleukin-6; Lipid Peroxidation; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Peptidyl-Dipeptidase A; Precancerous Conditions; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Tumor Necrosis Factor-alpha | 2014 |
The reconstructed skin micronucleus assay in EpiDerm™: reduction of false-positive results - a mechanistic study with epigallocatechin gallate.
Topics: Anticarcinogenic Agents; Catechin; Cells, Cultured; DNA Damage; False Positive Reactions; Gene Expression Regulation; Humans; Keratinocytes; Male; Micronuclei, Chromosome-Defective; Micronucleus Tests; Reagent Kits, Diagnostic | 2013 |
Epigallocatechin-3-O-gallate, a green tea polyphenol, induces expression of pim-1 kinase via PPARγ in human vascular endothelial cells.
Topics: Catechin; Gene Expression Regulation, Enzymologic; Human Umbilical Vein Endothelial Cells; Humans; Polyphenols; PPAR gamma; Proto-Oncogene Proteins c-pim-1; Tea | 2013 |
Green tea phenolics inhibit butyrate-induced differentiation of colon cancer cells by interacting with monocarboxylate transporter 1.
Topics: Adenocarcinoma; Alkaline Phosphatase; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Butyric Acid; Catechin; Cell Differentiation; Cell Membrane; Cell Proliferation; Colonic Neoplasms; Histamine Antagonists; Humans; Membrane Microdomains; Monocarboxylic Acid Transporters; Polyphenols; Tea; Tumor Cells, Cultured | 2013 |
Inhibition of urease activity in the urinary tract pathogen Staphylococcus saprophyticus.
Topics: Amides; Catechin; Culture Media; Enzyme Inhibitors; Flavonoids; Hydrogen-Ion Concentration; Hydroxamic Acids; Imidazoles; Kinetics; Staphylococcus saprophyticus; Urease; Urinary Tract; Urine; Virulence Factors | 2014 |
Epigallocatechin-3-gallate inhibits IGF-I-stimulated lung cancer angiogenesis through downregulation of HIF-1α and VEGF expression.
Topics: Base Sequence; Catechin; Cell Line, Tumor; DNA Primers; Down-Regulation; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin-Like Growth Factor I; Lung Neoplasms; Neovascularization, Pathologic; Real-Time Polymerase Chain Reaction; Vascular Endothelial Growth Factor A | 2013 |
Effects of epigallocatechin-3-gallate (EGCG) on A549 lung cancer tumor growth and angiogenesis.
Topics: Animals; Antineoplastic Agents; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Endostatins; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; RNA, Messenger; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2013 |
Activation of the hTAS2R14 human bitter-taste receptor by (-)-epigallocatechin gallate and (-)-epicatechin gallate.
Topics: Calcium; Catechin; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Receptors, G-Protein-Coupled | 2013 |
Nanoencapsulation enhances epigallocatechin-3-gallate stability and its antiatherogenic bioactivities in macrophages.
Topics: Atherosclerosis; Camellia sinensis; Cardiovascular Agents; Catechin; Cell Line; Chemokine CCL2; Cholesterol; Drug Compounding; Drug Stability; Humans; Macrophages; Nanoparticles; Plant Extracts | 2013 |
Methylated-(3'')-epigallocatechin gallate analog suppresses tumor growth in Huh7 hepatoma cells via inhibition of angiogenesis.
Topics: Animals; Antioxidants; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Human Umbilical Vein Endothelial Cells; Humans; Liver Neoplasms; Mice; Mitogen-Activated Protein Kinase 1; Neovascularization, Pathologic; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2014 |
Sphingosine-1-phosphate stimulated connective tissue growth factor expression in human buccal fibroblasts: Inhibition by epigallocatechin-3-gallate.
Topics: Areca; Catechin; Cells, Cultured; Connective Tissue Growth Factor; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Humans; Lysophospholipids; Oral Submucous Fibrosis; p38 Mitogen-Activated Protein Kinases; Signal Transduction; Sphingosine; Up-Regulation | 2015 |
Curcumin-induced upregulation of the anti-tau cochaperone BAG2 in primary rat cortical neurons.
Topics: Animals; Catechin; Cerebral Cortex; Curcumin; Lysosomal Membrane Proteins; Molecular Chaperones; Neurons; Primary Cell Culture; Rats; Resveratrol; Stilbenes; tau Proteins; Up-Regulation | 2013 |
Quercetin and EGCG exhibit chemopreventive effects in cholangiocarcinoma cells via suppression of JAK/STAT signaling pathway.
Topics: Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Catechin; Cell Line, Tumor; Cholangiocarcinoma; Humans; Intercellular Adhesion Molecule-1; Interferon-gamma; Interleukin-6; Janus Kinase 1; Janus Kinase 2; Nitric Oxide Synthase Type II; Phosphorylation; Quercetin; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; STAT5 Transcription Factor; Tumor Suppressor Proteins | 2014 |
Epigallocatechin-3-gallate inhibits stem-like inflammatory breast cancer cells.
Topics: Animals; Anticarcinogenic Agents; Breast; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Inflammatory Breast Neoplasms; Lymphangiogenesis; Mice; Mice, SCID; Neoplasm Invasiveness; Vascular Endothelial Growth Factor D | 2013 |
Exosome derived from epigallocatechin gallate treated breast cancer cells suppresses tumor growth by inhibiting tumor-associated macrophage infiltration and M2 polarization.
Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Chemokine CCL2; Disease Models, Animal; Exosomes; Female; Gene Expression Regulation, Neoplastic; I-kappa B Kinase; I-kappa B Proteins; Macrophage Colony-Stimulating Factor; Macrophages; Mice; MicroRNAs; Paracrine Communication | 2013 |
The aryl receptor inhibitor epigallocatechin-3-gallate protects INS-1E beta-cell line against acute dioxin toxicity.
Topics: Antioxidants; Catechin; Cell Line; Environmental Pollutants; Humans; Membrane Potential, Mitochondrial; Mitochondria; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon | 2013 |
Combined effects of green tea extracts, green tea polyphenols or epigallocatechin gallate with acarbose on inhibition against α-amylase and α-glucosidase in vitro.
Topics: Acarbose; alpha-Amylases; alpha-Glucosidases; Camellia sinensis; Catechin; Drug Synergism; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Plant Extracts; Polyphenols | 2013 |
Epigallocatechin-3-gallate and trichostatin A synergistically inhibit human lymphoma cell proliferation through epigenetic modification of p16INK4a.
Topics: Catechin; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; Drug Synergism; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Lymphoma; Promoter Regions, Genetic | 2013 |
Mechanism of the inhibition of the STAT3 signaling pathway by EGCG.
Topics: Apoptosis; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Molecular Docking Simulation; Phosphorylation; Protein Conformation; Signal Transduction; src Homology Domains; STAT3 Transcription Factor; Surface Plasmon Resonance; Tea | 2013 |
EGCG suppresses Fused Toes Homolog protein through p53 in cervical cancer cells.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis Regulatory Proteins; Catechin; Cell Survival; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; HeLa Cells; Humans; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-akt; RNA, Messenger; Tumor Suppressor Protein p53; Uterine Cervical Neoplasms | 2013 |
Green tea polyphenol epigallocatechin-3-gallate enhance glycogen synthesis and inhibit lipogenesis in hepatocytes.
Topics: Antioxidants; Catechin; Diabetes Mellitus, Type 2; Glycogen; Hep G2 Cells; Hepatocytes; Humans; Lipid Metabolism; Lipogenesis; Metabolic Syndrome; Phosphorylation; Proto-Oncogene Proteins c-akt; Tea | 2013 |
(-)-Epigallocatechin-3-gallate (EGCG) modulates neurological function when intravenously infused in acute and, chronically injured spinal cord of adult rats.
Topics: Animals; Behavior, Animal; Catechin; Female; Neurons; Neuroprotective Agents; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord; Spinal Cord Injuries | 2014 |
Oral administration of naturally occurring chitosan-based nanoformulated green tea polyphenol EGCG effectively inhibits prostate cancer cell growth in a xenograft model.
Topics: Administration, Oral; Animals; Anticarcinogenic Agents; bcl-2-Associated X Protein; Caspases; Catechin; Cell Proliferation; Chitosan; Enzyme-Linked Immunosorbent Assay; Humans; Immunoblotting; Immunoenzyme Techniques; Male; Mice; Mice, Nude; Nanoparticles; Nanotechnology; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proliferating Cell Nuclear Antigen; Prostate-Specific Antigen; Prostatic Neoplasms; Tea; Xenograft Model Antitumor Assays | 2014 |
In situ label-free imaging for visualizing the biotransformation of a bioactive polyphenol.
Topics: 2-Naphthylamine; Animals; Biotransformation; Catechin; Ions; Kidney; Liver; Male; Metabolic Detoxication, Phase II; Mice; Mice, Inbred C57BL; Molecular Imaging; Polyphenols; Reference Standards; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Staining and Labeling; Tissue Extracts | 2013 |
In vitro modulation of MMP-2 and MMP-9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Carcinogens; Catechin; Cell Line, Tumor; Chondrosarcoma; Dactinomycin; Dexamethasone; Doxycycline; Fibrosarcoma; Humans; Interleukin-1beta; Lipopolysaccharides; Liposarcoma; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Sarcoma; Sarcoma, Synovial; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Necrosis Factor-alpha | 2013 |
Comparison of (-)-epigallocatechin-3-O-gallate (EGCG) and O-methyl EGCG bioavailability in rats.
Topics: Animals; Area Under Curve; Biological Availability; Camellia sinensis; Catechin; Gallic Acid; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Tea | 2013 |
Evaluation of the bitter-masking potential of food proteins for EGCG by a cell-based human bitter taste receptor assay and binding studies.
Topics: Caseins; Catechin; Female; Humans; Kinetics; Male; Protein Binding; Receptors, Cell Surface; Taste | 2013 |
Green tea polyphenol, (-)-epigallocatechin-3-gallate, induces toxicity in human skin cancer cells by targeting β-catenin signaling.
Topics: Anticarcinogenic Agents; beta Catenin; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Delivery Systems; Humans; Polyphenols; Signal Transduction; Skin Neoplasms; Tea | 2013 |
UHPLC determination of catechins for the quality control of green tea.
Topics: Caffeine; Calibration; Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Electrochemistry; Geography; Kinetics; Mass Spectrometry; Micelles; Plant Extracts; Quality Control; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tea; Theobromine; Theophylline | 2014 |
In vitro and in vivo effects of (-)-epigallocatechin 3-O-gallate on Leishmania amazonensis.
Topics: Administration, Oral; Animals; Brazil; Catechin; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Leishmania mexicana; Macrophages; Male; Mice; Mice, Inbred BALB C; Molecular Structure; Stereoisomerism; Tea; Trypanosoma cruzi | 2013 |
Plant polyphenol induced cell death in human cancer cells involves mobilization of intracellular copper ions and reactive oxygen species generation: a mechanism for cancer chemopreventive action.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apigenin; Apoptosis; Catechin; Cell Death; Cell Line, Tumor; Cell Proliferation; Chelating Agents; Copper; Drug Screening Assays, Antitumor; Humans; Luteolin; Phenanthrolines; Polyphenols; Reactive Oxygen Species; Resveratrol; Stilbenes | 2014 |
Epigallocatechin-3-gallate inhibits hepatoblastoma growth by reactivating the Wnt inhibitor SFRP1.
Topics: Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Gene Silencing; Hepatoblastoma; Humans; Intercellular Signaling Peptides and Proteins; Membrane Proteins; Poly(ADP-ribose) Polymerases; Wnt Signaling Pathway | 2013 |
Combined taurine, epigallocatechin gallate and genistein therapy reduces HSC-T6 cell proliferation and modulates the expression of fibrogenic factors.
Topics: Animals; Catechin; Cell Line; Cell Proliferation; Collagen Type I; Down-Regulation; Drug Therapy, Combination; Genistein; Liver Cirrhosis; Matrix Metalloproteinase 2; Rats; RNA, Messenger; Taurine; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta1; Up-Regulation | 2013 |
Ion mobility spectrometry reveals the mechanism of amyloid formation of Aβ(25-35) and its modulation by inhibitors at the molecular level: epigallocatechin gallate and scyllo-inositol.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Catechin; Humans; Inositol; Mass Spectrometry; Models, Molecular; Peptide Fragments; Protein Multimerization; Protein Structure, Secondary | 2013 |
Epigallocatechin-3-gallate blocks triethylene glycol dimethacrylate-induced cyclooxygenase-2 expression by suppressing extracellular signal-regulated kinase in human dental pulp and embryonic palatal mesenchymal cells.
Topics: Catechin; Cell Culture Techniques; Cell Line; Cells, Cultured; Composite Resins; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dental Pulp; Extracellular Signal-Regulated MAP Kinases; Humans; MAP Kinase Signaling System; Mesenchymal Stem Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Palate; Polyethylene Glycols; Polymethacrylic Acids; Reactive Oxygen Species | 2013 |
DHA sensitizes FaO cells to tert-BHP-induced oxidative effects. Protective role of EGCG.
Topics: Animals; Catalase; Catechin; Cell Line, Tumor; Dietary Supplements; Docosahexaenoic Acids; Glutathione; Heme Oxygenase-1; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Protective Agents; Protein Transport; Rats; Reactive Oxygen Species; Tea; tert-Butylhydroperoxide | 2013 |
Effects of the green tea polyphenol epigallocatechin-3-gallate on high-fat diet-induced insulin resistance and endothelial dysfunction.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Catechin; Cattle; Cells, Cultured; Diet, High-Fat; Endothelial Cells; Endothelium, Vascular; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Polyphenols; Tea | 2013 |
Synergistic inhibition of lung cancer cell lines by (-)-epigallocatechin-3-gallate in combination with clinically used nitrocatechol inhibitors of catechol-O-methyltransferase.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Benzophenones; Blotting, Western; Catechin; Catechol O-Methyltransferase Inhibitors; Catechols; Cell Cycle; Cell Proliferation; Cell-Free System; DNA Methylation; Drug Synergism; Enzyme Inhibitors; Humans; Lung Neoplasms; Male; Mice; Nitriles; Nitro Compounds; Nitrophenols; Oxidative Stress; Reactive Oxygen Species; Tolcapone; Tumor Cells, Cultured | 2014 |
EGCG inhibit chemical reactivity of iron through forming an Ngal-EGCG-iron complex.
Topics: Acute-Phase Proteins; Antioxidants; Catechin; Chlorides; Chromatography, Liquid; Ferric Compounds; Ferrous Compounds; Iron; Lipocalin-2; Lipocalins; Mass Spectrometry; Oxidation-Reduction; Plant Extracts; Protein Binding; Proto-Oncogene Proteins; Reactive Oxygen Species; Recombinant Proteins; Tea | 2013 |
Epigallocatechin gallate induces embryonic toxicity in mouse blastocysts through apoptosis.
Topics: Animals; Apoptosis; Blastocyst; Catechin; Dose-Response Relationship, Drug; Embryo Implantation; Embryo Transfer; Embryonic Development; Female; Humans; MCF-7 Cells; Mice; Mice, Inbred ICR; Pregnancy; Signal Transduction | 2014 |
Resveratrol and EGCG bind directly and distinctively to miR-33a and miR-122 and modulate divergently their levels in hepatic cells.
Topics: Animals; ATP Binding Cassette Transporter 1; Catechin; Cell Line, Tumor; Fatty Acid Synthases; Flavonoids; Humans; Liver; MicroRNAs; Plant Extracts; Polyphenols; Rats; Resveratrol; Sterol Regulatory Element Binding Protein 2; Stilbenes; Vitis | 2014 |
Cellular targets for the beneficial actions of tea polyphenols.
Topics: Animals; Antioxidants; Biflavonoids; Camellia sinensis; Catechin; Humans; Neoplasms; Oxidants; Phytotherapy; Plant Extracts; Polyphenols; Signal Transduction; Tea | 2013 |
Epicatechin and epigallocatechin gallate inhibit formation of intermediary radicals during heating of lysine and glucose.
Topics: Camellia sinensis; Catechin; Free Radicals; Glucose; Hot Temperature; Hydrogen-Ion Concentration; Lysine; Maillard Reaction; Plant Extracts | 2014 |
Optimization of ultrasonic extraction of phenolic antioxidants from green tea using response surface methodology.
Topics: Antioxidants; Caffeine; Catechin; Phenols; Plant Extracts; Tea; Ultrasonics | 2013 |
In vitro modulation of MMP-2 and MMP-9 in pediatric human sarcoma cell lines by cytokines, inducers and inhibitors.
Topics: Catechin; Cell Line, Tumor; Child; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Osteosarcoma; Pediatrics; Rhabdomyosarcoma; Sarcoma; Tumor Necrosis Factor-alpha | 2014 |
Neuroprotection by (-)-epigallocatechin-3-gallate in a rat model of stroke is mediated through inhibition of endoplasmic reticulum stress.
Topics: Animals; Apoptosis; Caspase 12; Catechin; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Endoplasmic Reticulum Stress; Flavonoids; Heat-Shock Proteins; Male; Mitogen-Activated Protein Kinase Kinases; Neuroprotective Agents; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; Spectrin; Stroke; Transcription Factor CHOP; TRPC Cation Channels | 2014 |
(-)-Epigallocatechin-gallate (EGCG) stabilize the mitochondrial enzymes and inhibits the apoptosis in cigarette smoke-induced myocardial dysfunction in rats.
Topics: Animals; Antioxidants; Apoptosis; Body Weight; Catechin; Citric Acid Cycle; Electrophoresis, Agar Gel; Enzyme Stability; Glutathione; Heart; Lipid Peroxidation; Male; Mitochondria, Heart; Myocardium; Organ Size; Oxidative Stress; Rats; Rats, Wistar; Smoking | 2013 |
Combination of ascorbate/epigallocatechin-3-gallate/gemcitabine synergistically induces cell cycle deregulation and apoptosis in mesothelioma cells.
Topics: Apoptosis; Ascorbic Acid; Catechin; Cell Cycle; Cell Line, Tumor; Deoxycytidine; Drug Combinations; Drug Synergism; Gemcitabine; Humans; Mesothelioma | 2014 |
Antioxidant induces DNA damage, cell death and mutagenicity in human lung and skin normal cells.
Topics: Animals; Antioxidants; Apoptosis; Catechin; Cell Death; Cell Line; Cell Line, Tumor; Cell Survival; CHO Cells; Cricetulus; DNA Breaks, Double-Stranded; DNA Damage; Fibroblasts; Humans; Hydrogen Peroxide; Hypoxanthine Phosphoribosyltransferase; Inhibitory Concentration 50; Mutagenesis; Mutation; Plant Extracts; Tea | 2013 |
Dietary supplementation with (-)-epigallocatechin-3-gallate reduces inflammatory response in adipose tissue of non-obese type 2 diabetic Goto-Kakizaki (GK) rats.
Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Catechin; Diabetes Mellitus, Type 2; Dietary Supplements; Gene Expression Regulation; Inflammation; Male; Obesity; Oxidative Stress; Rats; Rats, Wistar | 2013 |
Green tea extract and its major constituent, epigallocatechin-3-gallate, induce epithelial beta-defensin secretion and prevent beta-defensin degradation by Porphyromonas gingivalis.
Topics: beta-Defensins; Butadienes; Camellia sinensis; Catechin; Cell Line; Cell Survival; Enzyme Inhibitors; Epithelial Cells; Gingiva; Humans; Imidazoles; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; p38 Mitogen-Activated Protein Kinases; Plant Extracts; Porphyromonas gingivalis; Proteolysis; Pyridines; Up-Regulation | 2014 |
Epigallocatechin-3-gallate attenuates Porphyromonas gingivalis lipopolysaccharide-enhanced matrix metalloproteinase-1 production through inhibition of interleukin-6 in gingival fibroblasts.
Topics: Adult; Antioxidants; Catechin; Cell Culture Techniques; Cell Survival; Cells, Cultured; Female; Fibroblasts; Gingiva; Humans; Interleukin-6; Lipopolysaccharides; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase Inhibitors; Microscopy, Confocal; NF-kappa B; Porphyromonas gingivalis; Young Adult | 2014 |
Epigallocatechin-3-gallate prevents tumor cell implantation/growth in an experimental rat bladder tumor model.
Topics: Animals; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Humans; Mitomycin; Neoplasms, Experimental; Rats; Urinary Bladder Neoplasms | 2014 |
Epigallocatechin-3-gallate inhibits homocysteine-induced apoptosis of endothelial cells by demethylation of the DDAH2 gene.
Topics: Amidohydrolases; Apoptosis; Azacitidine; Catechin; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Promoter Regions, Genetic; RNA, Messenger | 2013 |
The role of the mitochondrial oxidative stress in the cytotoxic effects of the green tea catechin, (-)-epigallocatechin-3-gallate, in oral cells.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Catechin; Cell Line, Tumor; Fibroblasts; Gene Expression Regulation; Gingiva; Humans; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Mitochondria; Mouth Neoplasms; Oxidative Stress; Reactive Oxygen Species; Tea | 2014 |
Epigallocatechin-3-gallate-mediated cardioprotection by Akt/GSK-3β/caveolin signalling in H9c2 rat cardiomyoblasts.
Topics: Animals; Catechin; Caveolin 1; Cell Line; Cell Survival; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hydrogen Peroxide; Myocytes, Cardiac; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Spectrometry, Fluorescence | 2013 |
Epigallocatechin gallate improves insulin signaling by decreasing toll-like receptor 4 (TLR4) activity in adipose tissues of high-fat diet rats.
Topics: Adipose Tissue; Animals; Catechin; Diet, High-Fat; Insulin; Interleukin-6; Macrophages; Male; Phosphatidylinositol 3-Kinase; Rats, Sprague-Dawley; Signal Transduction; Toll-Like Receptor 4 | 2014 |
Inhibition of Leishmania (Leishmania) amazonensis and rat arginases by green tea EGCG, (+)-catechin and (-)-epicatechin: a comparative structural analysis of enzyme-inhibitor interactions.
Topics: Animals; Anticarcinogenic Agents; Arginase; Catechin; Enzyme Inhibitors; Leishmania; Liver; Molecular Docking Simulation; Protozoan Proteins; Rats | 2013 |
Mechanism-based inhibition of cancer metastasis with (-)-epigallocatechin gallate.
Topics: Animals; Antineoplastic Agents; beta-Cyclodextrins; Catechin; Cell Line, Tumor; Cell Membrane; Cell Movement; Cholesterol; Elastic Modulus; Epithelial-Mesenchymal Transition; Humans; Mice; Microscopy, Atomic Force; Neoplasm Metastasis; Snail Family Transcription Factors; Transcription Factors; Vimentin | 2014 |
EGCG attenuates pro-inflammatory cytokines and chemokines production in LPS-stimulated L02 hepatocyte.
Topics: Anti-Inflammatory Agents; Catechin; Cell Line; Cell Survival; Cytokines; Hepatocytes; Humans; Intercellular Adhesion Molecule-1; Lipopolysaccharides; Matrix Metalloproteinase 2; Mitogen-Activated Protein Kinases; NF-kappa B; Tumor Necrosis Factor-alpha | 2014 |
The spectral properties of (-)-epigallocatechin 3-O-gallate (EGCG) fluorescence in different solvents: dependence on solvent polarity.
Topics: Acetonitriles; Catechin; Dimethyl Sulfoxide; Ethanol; Solvents; Spectrometry, Fluorescence | 2013 |
Epigallocatechin gallate attenuates ET-1-induced contraction in carotid artery from type 2 diabetic OLETF rat at chronic stage of disease.
Topics: Acetylcholine; Animals; Carotid Arteries; Catechin; Chronic Disease; Diabetes Mellitus, Experimental; Endothelin-1; In Vitro Techniques; Male; NADPH Oxidases; Nitric Oxide Synthase Type III; Nitroprusside; Phenylephrine; Rats, Inbred OLETF; Receptors, Endothelin; Superoxide Dismutase; Vasoconstriction; Vasodilation | 2014 |
Epigallocatechin-3-gallate-capped Ag nanoparticles: preparation and characterization.
Topics: Camellia sinensis; Catechin; Cetrimonium; Cetrimonium Compounds; Hydroxyl Radical; Ions; Metal Nanoparticles; Microscopy, Electron, Transmission; Nanoparticles; Nanotechnology; Oxygen; Plant Extracts; Plant Leaves; Silver; Spectrophotometry, Ultraviolet | 2014 |
Epigallocatechin-3-gallate, a green tea catechin, protects the heart against regional ischemia-reperfusion injuries through activation of RISK survival pathways in rats.
Topics: Animals; Camellia sinensis; Cardiotonic Agents; Catechin; Cell Death; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Male; MAP Kinase Signaling System; Myocardial Reperfusion Injury; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley | 2014 |
Mitogenesis of vascular smooth muscle cell stimulated by platelet-derived growth factor-bb is inhibited by blocking of intracellular signaling by epigallocatechin-3-O-gallate.
Topics: Animals; Aorta; Becaplermin; Catechin; Cell Cycle Checkpoints; Cell Proliferation; Humans; Intracellular Space; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mitogens; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protective Agents; Proto-Oncogene Proteins c-sis; Rats; Signal Transduction | 2013 |
Epigallocatechin-3-gallate improves plantaris muscle recovery after disuse in aged rats.
Topics: Aging; Animals; Apoptosis; Body Weight; Catechin; Drug Evaluation, Preclinical; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hindlimb Suspension; Isometric Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Muscular Atrophy; Organ Size; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred BN; Rats, Inbred F344; Signal Transduction; Stem Cells; Weight-Bearing | 2014 |
Epigallocatechin gallate does not accelerate the early phase of liver regeneration after partial hepatectomy in rats.
Topics: Animals; Antioxidants; Caspases; Catechin; Cell Cycle Proteins; Cytokines; Gene Expression Regulation; Heme Oxygenase-1; Hepatectomy; Liver Regeneration; Male; NAD(P)H Dehydrogenase (Quinone); Oxidative Stress; Rats; Rats, Wistar; RNA, Messenger | 2014 |
Green tea polyphenol epigallocatechin 3-gallate, contributes to the degradation of DNMT3A and HDAC3 in HCT 116 human colon cancer cells.
Topics: Base Sequence; Catechin; Colonic Neoplasms; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; DNA Primers; HCT116 Cells; Histone Deacetylases; Humans; Proteolysis; Real-Time Polymerase Chain Reaction; Tea | 2013 |
Epigallocatechin-3-gallate prevents autoimmune-associated down- regulation of p21 in salivary gland cells through a p53-independent pathway.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Diabetes Mellitus, Type 1; Disease Models, Animal; Down-Regulation; Epithelial Cells; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Proliferating Cell Nuclear Antigen; Retinoblastoma Protein; Salivary Glands; Sjogren's Syndrome; Tumor Suppressor Protein p53; Xerostomia | 2014 |
Association of caspase-14 and filaggrin expression with keratinization of the oral mucosa and reconstruction culture rat models.
Topics: Animals; Animals, Newborn; Caspase 14; Catechin; Cell Culture Techniques; Epithelial Cells; Epithelium; Esophagus; Fibroblasts; Filaggrin Proteins; Intermediate Filament Proteins; Keratin-10; Keratins; Models, Animal; Mouth Mucosa; Palate; Phosphoproteins; Protease Inhibitors; Rats; Rats, Wistar; Skin; Tissue Culture Techniques | 2014 |
Induction of the connexin 32 gene by epigallocatechin-3-gallate potentiates vinblastine-induced cytotoxicity in human renal carcinoma cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Renal Cell; Catechin; Cell Line, Tumor; Cell Survival; Connexins; DNA Methylation; Gap Junction beta-1 Protein; Humans; Promoter Regions, Genetic; RNA Interference; RNA, Messenger; RNA, Small Interfering; Up-Regulation; Vinblastine | 2013 |
(-)-Epigallocatechin-3-gallate suppresses liver metastasis of human colorectal cancer.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Enzyme Activation; HCT116 Cells; Humans; Liver Neoplasms; Male; Mice; Mice, SCID; Neovascularization, Pathologic; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Vascular Endothelial Growth Factor Receptor-2 | 2014 |
Epigallocatechin-3-gallate induces apoptosis, inhibits proliferation and decreases invasion of glioma cell.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Glioma; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Matrix Metalloproteinase 9 | 2014 |
Simultaneous detection of green tea catechins and gallic acid in human serum after ingestion of green tea tablets using ion-pair high-performance liquid chromatography with electrochemical detection.
Topics: Administration, Oral; Adult; Catechin; Chromatography, High Pressure Liquid; Electrochemical Techniques; Female; Gallic Acid; Humans; Male; Middle Aged; Tablets; Tea; Young Adult | 2014 |
(-)-Epigallocatechin-3-gallate ameliorates learning and memory deficits by adjusting the balance of TrkA/p75NTR signaling in APP/PS1 transgenic mice.
Topics: Amyloid beta-Protein Precursor; Animals; Avoidance Learning; Catechin; Male; Memory Disorders; Mice; Mice, Transgenic; Presenilin-1; Receptor, trkA; Receptors, Nerve Growth Factor; Signal Transduction | 2014 |
Antiproliferative activity of tea catechins associated with casein micelles, using HT29 colon cancer cells.
Topics: Antioxidants; Camellia sinensis; Caseins; Catechin; Cell Proliferation; HT29 Cells; Humans; Micelles; Nanoparticles; Polyphenols | 2014 |
Covalent complexation and functional evaluation of (-)-epigallocatechin gallate and α-lactalbumin.
Topics: Antioxidants; Catechin; Emulsions; Hydrogen-Ion Concentration; Lactalbumin; Protein Binding; Protein Conformation; Temperature | 2014 |
Epigallocatechin gallate inhibits the growth of human lung cancer by directly targeting the EGFR signaling pathway.
Topics: Antineoplastic Agents; Catechin; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; ErbB Receptors; G1 Phase Cell Cycle Checkpoints; Gene Expression; Gene Knockdown Techniques; Humans; Lung Neoplasms; Signal Transduction | 2014 |
Synergistic effect of the flavonoid catechin, quercetin, or epigallocatechin gallate with fluconazole induces apoptosis in Candida tropicalis resistant to fluconazole.
Topics: Antifungal Agents; Apoptosis; Candida tropicalis; Catechin; Drug Interactions; Drug Resistance, Fungal; Drug Synergism; Fluconazole; Microbial Sensitivity Tests; Quercetin; Reactive Oxygen Species | 2014 |
Epigallocatechin-3-gallate (EGCG) attenuates concanavalin A-induced hepatic injury in mice.
Topics: Animals; Catechin; Chemical and Drug Induced Liver Injury; Concanavalin A; Disease Models, Animal; Male; Mice, Inbred C57BL; Oxidative Stress; Toll-Like Receptors; Tumor Necrosis Factor-alpha | 2014 |
Green tea epigallocatechin gallate binds to and inhibits respiratory complexes in swelling but not normal rat hepatic mitochondria.
Topics: Animals; Blotting, Western; Catechin; Electron Transport Chain Complex Proteins; Electrophoresis, Polyacrylamide Gel; Male; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Oxidative Phosphorylation; Protein Binding; Protein Subunits; Rats; Rats, Sprague-Dawley; Silver Staining; Tea | 2014 |
Sequentially releasing dual-drug-loaded PLGA-casein core/shell nanomedicine: design, synthesis, biocompatibility and pharmacokinetics.
Topics: Animals; Biocompatible Materials; Caseins; Catechin; Cell Death; Cell Line; Chromatography, High Pressure Liquid; Cytokines; Humans; Indocyanine Green; Inflammation; Lactic Acid; Materials Testing; Mice; Nanomedicine; Nanoparticles; Organ Specificity; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2014 |
Binding interaction between (-)-epigallocatechin gallate causes impaired spreading of cancer cells on fibrinogen.
Topics: Animals; Binding Sites; Catechin; Cattle; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cyanogen Bromide; Fibrinogen; Humans; Mice; Peptides; Protein Binding; Protein Structure, Tertiary; Protein Subunits; Thermolysin | 2013 |
Epigallocatechin gallate inhibits oxidative stress-induced DNA damage and apoptosis in MRL-Fas(lpr) mice with autoimmune sialadenitis via upregulation of heme oxygenase-1 and Bcl-2.
Topics: Animals; Antioxidants; Apoptosis; Autoantigens; Autoimmune Diseases; Catechin; Disease Models, Animal; DNA Damage; Gene Expression Regulation; Heme Oxygenase-1; Mice; Mice, Inbred MRL lpr; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Severity of Illness Index; Sialadenitis; Submandibular Gland | 2014 |
EGCG inhibits Cd(2+)-induced apoptosis through scavenging ROS rather than chelating Cd(2+) in HL-7702 cells.
Topics: Apoptosis; Cadmium; Catechin; Cell Line; Chelating Agents; Free Radical Scavengers; Humans; Liver; Malondialdehyde; Membrane Potential, Mitochondrial; Oxidative Stress; Proton Magnetic Resonance Spectroscopy; Reactive Oxygen Species; Spectrophotometry, Ultraviolet | 2014 |
Epigallocatechin-3-gallate inhibits cell growth, induces apoptosis and causes S phase arrest in hepatocellular carcinoma by suppressing the AKT pathway.
Topics: Apoptosis; Carcinoma, Hepatocellular; Catechin; Cell Cycle Checkpoints; Cell Proliferation; Humans; Liver Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; S Phase; Signal Transduction | 2014 |
Green tea and one of its constituents, Epigallocatechine-3-gallate, are potent inhibitors of human 11β-hydroxysteroid dehydrogenase type 1.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Catechin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Hydrocortisone; Kinetics; Microsomes, Liver; Plant Extracts; Tea | 2014 |
Molecular mechanism of (-)-epigallocatechin-3-gallate on balloon injury-induced neointimal formation and leptin expression.
Topics: Angioplasty, Balloon; Angiotensin II; Animals; Aorta, Thoracic; Carotid Arteries; Carotid Artery Injuries; Catechin; Cell Movement; Cells, Cultured; Leptin; Male; Muscle, Smooth, Vascular; Neointima; Rats; Rats, Wistar; RNA, Small Interfering | 2014 |
Arecoline stimulated early growth response-1 production in human buccal fibroblasts: suppression by epigallocatechin-3-gallate.
Topics: Arecoline; Blotting, Western; Catechin; Cheek; Cholinergic Agonists; Early Growth Response Protein 1; Humans; Immunohistochemistry; Mouth Mucosa; Oral Submucous Fibrosis; Signal Transduction | 2015 |
Elasto-regenerative properties of polyphenols.
Topics: Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Catechin; Cells, Cultured; Elastic Tissue; Elastin; Fibrillins; Hydrolyzable Tannins; Kinetics; Male; Matrix Metalloproteinase 2; Microfilament Proteins; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Polyphenols; Protein-Lysine 6-Oxidase; Rats; Rats, Sprague-Dawley; Regeneration; Tropoelastin | 2014 |
Epigallocatechin-3-gallate modulates anti-oxidant defense enzyme expression in murine submandibular and pancreatic exocrine gland cells and human HSG cells.
Topics: Animals; Antioxidants; Catechin; Cell Line, Tumor; Gene Expression; Gene Expression Regulation; Humans; Hydrogen Peroxide; Mice; Mice, Inbred NOD; Mitogen-Activated Protein Kinases; Pancreas, Exocrine; Peroxiredoxin VI; Protein Kinase Inhibitors; Submandibular Gland | 2014 |
Epigallocatechin-3-gallate inhibits lysophosphatidic acid-stimulated connective tissue growth factor via JNK and Smad3 suppression in human gingival fibroblasts.
Topics: Catechin; Cells, Cultured; Connective Tissue Growth Factor; Curcumin; Fibroblasts; Gingiva; Humans; Lysophospholipids; MAP Kinase Kinase 4; Smad3 Protein; Wound Healing | 2014 |
Fabrication of self-assembled (-)-epigallocatechin gallate (EGCG) ovalbumin-dextran conjugate nanoparticles and their transport across monolayers of human intestinal epithelial Caco-2 cells.
Topics: Caco-2 Cells; Catechin; Dextrans; Digestion; Drug Stability; Gastrointestinal Tract; Glutaral; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Maillard Reaction; Nanoparticles; Ovalbumin; Particle Size | 2014 |
PPARα activation sensitizes cancer cells to epigallocatechin-3-gallate (EGCG) treatment via suppressing heme oxygenase-1.
Topics: Antioxidants; Catechin; Cell Death; Cell Line, Tumor; Cell Survival; Chromatin Immunoprecipitation; Heme Oxygenase-1; Humans; PPAR alpha; Promoter Regions, Genetic; RNA, Small Interfering; Tea | 2014 |
Epigallocatechin‑3‑gallate inhibits the proliferation and migration of human ovarian carcinoma cells by modulating p38 kinase and matrix metalloproteinase‑2.
Topics: Anticarcinogenic Agents; Carcinoma; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Enzyme Activation; Female; Humans; Imidazoles; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Ovarian Neoplasms; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Biosynthesis; Pyridines | 2014 |
Epigallocatechin 3-O-gallate induces 67 kDa laminin receptor-mediated cell death accompanied by downregulation of ErbB proteins and altered lipid raft clustering in mammary and epidermoid carcinoma cells.
Topics: Algorithms; Anticarcinogenic Agents; Apoptosis; Carcinoma, Squamous Cell; Catechin; Cell Proliferation; Down-Regulation; ErbB Receptors; Female; Flavonoids; G2 Phase Cell Cycle Checkpoints; Genes, erbB-1; Genes, erbB-2; Genistein; Glycine max; Humans; Molecular Structure; Polyphenols; Receptors, Laminin; Ribosomal Proteins; Tea | 2014 |
Autophagy inhibition contributes to the synergistic interaction between EGCG and doxorubicin to kill the hepatoma Hep3B cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Humans; Liver Neoplasms; Mice; Mice, Nude; Up-Regulation; Xenograft Model Antitumor Assays | 2014 |
Effects of the tea catechin epigallocatechin gallate on Porphyromonas gingivalis biofilms.
Topics: Anti-Bacterial Agents; Biofilms; Catechin; Porphyromonas gingivalis | 2014 |
NitroDIGE analysis reveals inhibition of protein S-nitrosylation by epigallocatechin gallates in lipopolysaccharide-stimulated microglial cells.
Topics: Animals; Catechin; Cell Line, Transformed; Chromatography, Liquid; Cysteine; Lipopolysaccharides; Mice; Microglia; Neuroprotective Agents; Nitric Oxide Synthase; Peroxiredoxins; Phosphorylation; Proteomics; S-Nitrosothiols; Signal Transduction; Superoxide Dismutase; Tandem Mass Spectrometry; Ubiquitin Thiolesterase | 2014 |
Impact of 5-aza-2'-deoxycytidine and epigallocatechin-3-gallate for induction of human regulatory T cells.
Topics: Azacitidine; Catechin; Decitabine; Forkhead Transcription Factors; Humans; Male; Methylation; Oligonucleotide Array Sequence Analysis; T-Lymphocytes, Regulatory | 2014 |
Dietary supplementation with a low dose of (-)-epigallocatechin-3-gallate reduces pro-inflammatory responses in peripheral leukocytes of non-obese type 2 diabetic GK rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Analysis of Variance; Animals; Catechin; Chemokines; Corn Oil; Cytokines; Deoxyguanosine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet; Diet, High-Fat; Dietary Fats; Dietary Supplements; Disease Models, Animal; Inflammation; Leukocytes; Male; Malondialdehyde; Oxidative Stress; Polymerase Chain Reaction; Rats; Rats, Wistar | 2013 |
Epigallocatechin-3-gallate inhibits TF and TNF-α expression induced by the anti-β2GPI/β2GPI complex in human THP-1 cells.
Topics: Antibodies; beta 2-Glycoprotein I; Catechin; Cell Line; Enzyme Activation; Humans; MAP Kinase Signaling System; NF-kappa B; RNA, Messenger; Thromboplastin; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2014 |
Epigenetic induction of tissue inhibitor of matrix metalloproteinase-3 by green tea polyphenols in breast cancer cells.
Topics: Acetylation; Breast; Breast Neoplasms; Catechin; Cell Line, Tumor; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Polyphenols; Promoter Regions, Genetic; Tea; Tissue Inhibitor of Metalloproteinase-3 | 2015 |
Green tea (-)-epigallocatechin gallate suppresses IGF-I and IGF-II stimulation of 3T3-L1 adipocyte glucose uptake via the glucose transporter 4, but not glucose transporter 1 pathway.
Topics: 3T3-L1 Cells; Acetylcysteine; Adipocytes; Animals; Antibodies; Catechin; Cell Membrane; Cytoplasm; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Mice; Phosphorylation; Protein Transport; Receptors, Laminin; Signal Transduction; Tea | 2014 |
Epigallocatechin gallate counteracts oxidative stress in docosahexaenoxic acid-treated myocytes.
Topics: Animals; Calcium; Catechin; Cells, Cultured; Docosahexaenoic Acids; Mitochondria, Muscle; Muscle, Skeletal; Oxidative Phosphorylation; Oxidative Stress; Reactive Oxygen Species | 2014 |
Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, stimulates hepatic autophagy and lipid clearance.
Topics: Adenylate Kinase; Animals; Autophagy; Catechin; Diet, High-Fat; Fatty Liver; Hep G2 Cells; Hepatocytes; Humans; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Phagosomes; Tea | 2014 |
Noncompetitive inhibition of proton-coupled folate transporter by myricetin.
Topics: Animals; Biological Transport; Catechin; Cell Line; Dogs; Flavonoids; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Proton-Coupled Folate Transporter | 2014 |
Inhibitory activity of synthesized acetylated Procyanidin B1 analogs against HeLa S3 cells proliferation.
Topics: Acetylation; Biflavonoids; Catechin; Cell Proliferation; HeLa Cells; Humans; Neoplasms; Polymers; Proanthocyanidins; Tea | 2014 |
Green tea catechins potentiate the neuritogenic action of brain-derived neurotrophic factor: role of 67-kDa laminin receptor and hydrogen peroxide.
Topics: Animals; Antioxidants; Brain-Derived Neurotrophic Factor; Catechin; Dose-Response Relationship, Drug; Drug Synergism; Hydrogen Peroxide; Molecular Weight; Neurites; Oxidants; PC12 Cells; Polyphenols; Rats; Receptor, trkB; Receptors, Laminin; Tea | 2014 |
Curcumin and (-)-epigallocatechin-3-gallate attenuate acrylamide-induced proliferation in HepG2 cells.
Topics: Acrylamide; Catechin; Cell Proliferation; Curcumin; Hep G2 Cells; Humans | 2014 |
Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Butyric Acid; Catechin; Cell Cycle Checkpoints; Cell Proliferation; Colonic Neoplasms; Down-Regulation; Epigenesis, Genetic; HCT116 Cells; HT29 Cells; Humans; Signal Transduction; Tumor Cells, Cultured | 2014 |
Epigallocatechin gallate eye drops protect against ultraviolet B-induced corneal oxidative damage in mice.
Topics: Animals; Antioxidants; Catalase; Catechin; Cornea; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; Lissamine Green Dyes; Male; Mice; Mice, Inbred ICR; Ophthalmic Solutions; Oxidative Stress; Protective Agents; Protein Carbonylation; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Ultraviolet Rays | 2014 |
Reduction of microbiological risk in minced meat by a combination of natural antimicrobials.
Topics: Alpinia; Animals; Anti-Bacterial Agents; Antioxidants; Campylobacter jejuni; Catechin; Cattle; Chickens; Escherichia coli; Food Handling; Food Preservatives; Food Storage; Listeria monocytogenes; Meat; Microbial Viability; Phytochemicals; Plant Extracts; Refrigeration; Seeds; Sus scrofa | 2014 |
EGCG attenuates autoimmune arthritis by inhibition of STAT3 and HIF-1α with Th17/Treg control.
Topics: Animals; Antioxidants; Arthritis; Autoimmune Diseases; Catechin; Cell Differentiation; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Mice; Mice, Inbred BALB C; Mice, Knockout; Osteoclasts; Oxidative Stress; Receptors, Interleukin-1; STAT3 Transcription Factor; T-Lymphocytes, Regulatory; Th17 Cells | 2014 |
Epigallocatechin gallate (EGCG) prevents H2O2-induced oxidative stress in primary rat retinal pigment epithelial cells.
Topics: Animals; Animals, Newborn; Antioxidants; Apoptosis; Catechin; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Flow Cytometry; Hydrogen Peroxide; Oxidants; Oxidative Stress; Rats; Rats, Long-Evans; Retinal Pigment Epithelium | 2014 |
Cyclosporine A induces connective tissue growth factor expression in human gingival fibroblasts: suppression by epigallocatechin-3-gallate.
Topics: Catechin; Connective Tissue Growth Factor; Cyclosporine; Fibroblasts; Gingiva; Gingival Overgrowth; Humans; Primary Cell Culture; Transforming Growth Factor beta1 | 2014 |
In vitro evaluation of the antiviral activity of the synthetic epigallocatechin gallate analog-epigallocatechin gallate (EGCG) palmitate against porcine reproductive and respiratory syndrome virus.
Topics: Animals; Antiviral Agents; Catechin; Cell Line; Cell Survival; Cytopathogenic Effect, Viral; Microbial Viability; Palmitates; Porcine respiratory and reproductive syndrome virus; Swine | 2014 |
Promotion of full-thickness wound healing using epigallocatechin-3-O-gallate/poly (lactic-co-glycolic acid) membrane as temporary wound dressing.
Topics: Adult; Animals; Antioxidants; Bandages; Catechin; Cell Line; Humans; Lactic Acid; Male; Membranes, Artificial; Mice; Mice, Inbred BALB C; Mice, Nude; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Wound Healing | 2014 |
Modeling of chemical inhibition from amyloid protein aggregation kinetics.
Topics: Amyloid beta-Peptides; Apigenin; Biflavonoids; Catechin; Flavones; Insulin; Insulin Antagonists; Kinetics; Models, Biological; Peptide Fragments; Phosphatidylcholines; Pyruvaldehyde | 2014 |
Immunoprotective effect of epigallocatechin-3-gallate on oral anticancer drug-induced α-defensin reduction in Caco-2 cells.
Topics: alpha-Defensins; Antimetabolites, Antineoplastic; Antioxidants; Caco-2 Cells; Catechin; Herb-Drug Interactions; Humans; Hydrogen Peroxide; Intestinal Mucosa; Neoplasms; Plant Extracts; Reactive Oxygen Species; RNA, Messenger; Tegafur | 2014 |
Epigallocatechin-3-gallate restores the Bcl-2 expression in liver of young rats challenged with hypercholesterolemia but not in aged rats: an insight into its disparity of efficacy on advancing age.
Topics: Age Factors; Animals; Apoptosis; Catechin; Disease Models, Animal; Humans; Hypercholesterolemia; Liver; Male; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar | 2014 |
Differences in heat stability and ligand binding among β-lactoglobulin genetic variants A, B and C using (1)H NMR and fluorescence quenching.
Topics: Animals; Binding Sites; Catechin; Cattle; Circular Dichroism; Kinetics; Lactoglobulins; Magnetic Resonance Spectroscopy; Protein Binding; Protein Stability; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence; Vitamin A | 2014 |
Antigenotoxic effects of (-)-epigallocatechin-3-gallate (EGCG), quercetin, and rutin on chromium trioxide-induced micronuclei in the polychromatic erythrocytes of mouse peripheral blood.
Topics: Animals; Antioxidants; Catechin; Chromium Compounds; DNA Damage; Erythrocytes; Female; Mice; Micronucleus Tests; Quercetin; Reactive Oxygen Species; Rutin | 2014 |
Identifying key non-volatile compounds in ready-to-drink green tea and their impact on taste profile.
Topics: Caffeine; Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Humans; Plant Extracts; Taste; Tea | 2014 |
A new antioxidant beverage produced with green tea and apple.
Topics: Antioxidants; Beverages; Catechin; Chromatography, High Pressure Liquid; Flavonoids; Hydrogen-Ion Concentration; Malus; Phenols; Tea | 2014 |
Epigallocatechin-3-gallate inhibits tax-dependent activation of nuclear factor kappa B and of matrix metalloproteinase 9 in human T-cell lymphotropic virus-1 positive leukemia cells.
Topics: Antioxidants; Catechin; Cell Line, Tumor; Cell Proliferation; Gene Products, tax; Human T-lymphotropic virus 1; Humans; Leukemia-Lymphoma, Adult T-Cell; Matrix Metalloproteinase 9; Neuroprotective Agents; NF-kappa B; Transcription, Genetic; Transcriptional Activation; Urokinase-Type Plasminogen Activator | 2014 |
Effect of topical epigallocatechin gallate on corneal neovascularization in rabbits.
Topics: Administration, Topical; Angiogenesis Inhibitors; Animals; Antioxidants; Blotting, Western; Catechin; Cornea; Corneal Neovascularization; Cyclooxygenase 2; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Ophthalmic Solutions; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vascular Endothelial Growth Factor A | 2014 |
Chemopreventive and hepatoprotective effects of Epigallocatechin-gallate against hepatocellular carcinoma: role of heparan sulfate proteoglycans pathway.
Topics: alpha-Fetoproteins; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Ascorbic Acid; Camellia sinensis; Carcinoma, Hepatocellular; Catechin; Fibroblast Growth Factor 2; Gene Expression; Hep G2 Cells; Heparan Sulfate Proteoglycans; Humans; Liver; Liver Neoplasms; Male; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Phytotherapy; Plant Extracts; Rats, Sprague-Dawley; Syndecan-1; Thioacetamide | 2014 |
Effects of the vegetable polyphenols epigallocatechin-3-gallate, luteolin, apigenin, myricetin, quercetin, and cyanidin in primary cultures of human retinal pigment epithelial cells.
Topics: Anthocyanins; Apigenin; Catechin; Cell Death; Cell Proliferation; Cell Survival; Cells, Cultured; Chemotaxis; DNA Fragmentation; Epithelial Cells; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Indoles; Intracellular Space; Luteolin; Phosphorylation; Polyphenols; Quercetin; Retinal Pigment Epithelium; RNA, Messenger; Signal Transduction; Vascular Endothelial Growth Factor A; Vegetables | 2014 |
Epigallocatechin gallate decreases the micellar solubility of cholesterol via specific interaction with phosphatidylcholine.
Topics: Bile Acids and Salts; Camellia sinensis; Catechin; Cholesterol; Humans; Intestinal Absorption; Kinetics; Micelles; Models, Biological; Phosphatidylcholines; Plant Extracts; Solubility | 2014 |
Stability of catechins in green tea nutraceutical products: application of solid phase extraction-thin layer chromatography densitometry.
Topics: Camellia sinensis; Catechin; Chromatography, Thin Layer; Dietary Supplements; Mass Spectrometry; Plant Extracts; Solid Phase Extraction; Tea | 2014 |
Delivery of green tea catechin and epigallocatechin gallate in liposomes incorporated into low-fat hard cheese.
Topics: Antioxidants; Catechin; Cheese; Liposomes; Nanocapsules; Tea | 2014 |
Epigallocatechin gallate with photodynamic therapy enhances anti-tumor effects in vivo and in vitro.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Drug Combinations; Drug Synergism; Female; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Photochemotherapy; Photosensitizing Agents; Porphyrins; Treatment Outcome; Tumor Burden | 2014 |
Identification of Novel Polyphenolic Inhibitors of Shikimate Dehydrogenase (AroE).
Topics: Alcohol Oxidoreductases; Arabidopsis; Bacterial Proteins; Binding Sites; Catechin; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; Inhibitory Concentration 50; Kinetics; Microbial Sensitivity Tests; Polyphenols; Protein Domains; Pseudomonas putida; Sequence Alignment; Sequence Homology, Amino Acid; Spectrophotometry | 2014 |
The effect of epigallocatechin-3-gallate (EGCG) on human alveolar bone cells both in vitro and in vivo.
Topics: Alkaline Phosphatase; Alveolar Process; Animals; Apoptosis; Calcium Phosphates; Catechin; Cell Movement; Cell Proliferation; Child; Female; Flow Cytometry; Gene Expression; Humans; In Vitro Techniques; Male; Mice; Osteogenesis; Reverse Transcriptase Polymerase Chain Reaction | 2014 |
Green tea decoction improves glucose tolerance and reduces weight gain of rats fed normal and high-fat diet.
Topics: Administration, Oral; Animals; Caffeine; Catechin; Diet, High-Fat; Glucose; Glucose Tolerance Test; Glucose Transporter Type 2; Glucose Transporter Type 4; Lipids; Male; Polyphenols; Protein Transport; Rats, Wistar; Sodium-Glucose Transporter 1; Tea; Weight Gain | 2014 |
Peptides derived from HIV-1 gp120 co-receptor binding domain form amyloid fibrils and enhance HIV-1 infection.
Topics: Amino Acid Sequence; Amyloid; Anti-HIV Agents; Catechin; Cell Line; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Inhibitory Concentration 50; Molecular Sequence Data; Peptide Fragments; Protein Interaction Domains and Motifs; Virus Internalization | 2014 |
Fabrication of epigallocatechin-3-gallate nanocarrier based on glycosylated casein: stability and interaction mechanism.
Topics: Caseins; Catechin; Drug Carriers; Drug Stability; Glycosylation; Maillard Reaction; Nanoparticles | 2014 |
Epigallocatechin-3-gallate (EGCG) as a pro-osteogenic agent to enhance osteogenic differentiation of mesenchymal stem cells from human bone marrow: an in vitro study.
Topics: Alkaline Phosphatase; Antioxidants; Bone Marrow Cells; Bone Morphogenetic Protein 2; Catechin; Cell Differentiation; Cell Lineage; Cell Proliferation; Cell- and Tissue-Based Therapy; Core Binding Factor Alpha 1 Subunit; Humans; Mesenchymal Stem Cells; Osteogenesis; Osteoporosis; Tea; Urokinase-Type Plasminogen Activator | 2014 |
Bioefficacy of tea catechins encapsulated in casein micelles tested on a normal mouse cell line (4D/WT) and its cancerous counterpart (D/v-src) before and after in vitro digestion.
Topics: Animals; Caseins; Catechin; Cell Line; Cell Line, Tumor; Cell Proliferation; Mice; Micelles; Polyphenols; Rats; Tea | 2014 |
Effects of green tea compound epigallocatechin-3-gallate against Stenotrophomonas maltophilia infection and biofilm.
Topics: Animals; Bacterial Load; Biofilms; Catechin; Colistin; Female; Instillation, Drug; Kinetics; Mice, Inbred C57BL; Mice, Mutant Strains; Microbial Sensitivity Tests; Stenotrophomonas maltophilia; Tea | 2014 |
Epigallocatechin-3-gallate ameliorates seawater aspiration-induced acute lung injury via regulating inflammatory cytokines and inhibiting JAK/STAT1 pathway in rats.
Topics: Acute Lung Injury; Animals; Arterial Pressure; Bronchoalveolar Lavage Fluid; Catechin; Cytokines; Interleukin-1; Interleukin-10; Janus Kinase 1; Janus Kinase 2; Macrophages; Male; Oxygen; Partial Pressure; Phosphorylation; Rats; Rats, Sprague-Dawley; Respiratory Aspiration; Seawater; Signal Transduction; STAT1 Transcription Factor; Tumor Necrosis Factor-alpha | 2014 |
Effect of epigallocatechin gallate on drug transport mediated by the proton-coupled folate transporter.
Topics: Caco-2 Cells; Catechin; Cells, Cultured; Folic Acid; HEK293 Cells; Humans; Methotrexate; Proton-Coupled Folate Transporter | 2014 |
Analysis of green tea compounds and their stability in dentifrices of different pH levels.
Topics: Catechin; Chromatography, Liquid; Dentifrices; Flavonoids; Hydrogen-Ion Concentration; Tea; Temperature; Toothpastes | 2014 |
Interactions among chemical components of Cocoa tea (Camellia ptilophylla Chang), a naturally low caffeine-containing tea species.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Caffeine; Camellia; Camellia sinensis; Catechin; Cell Line, Tumor; China; Chromatography, High Pressure Liquid; Lipopolysaccharides; Mice; Nitric Oxide; Phytochemicals; Plant Extracts; Plant Leaves; Polyphenols; Tea; Xanthines | 2014 |
(-)-Epigallocatechin-3-gallate ameliorates photodynamic therapy responses in an in vitro T lymphocyte model.
Topics: Apoptosis; Caspase 3; Catalase; Catechin; Cell Proliferation; DNA Fragmentation; Humans; Hydrogen Peroxide; Interferon-gamma; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Photochemotherapy; Prohibitins; Reactive Oxygen Species | 2014 |
EGCG enhances the efficacy of cisplatin by downregulating hsa-miR-98-5p in NSCLC A549 cells.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Cisplatin; Computational Biology; Down-Regulation; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Transfection; Up-Regulation | 2014 |
Role of the flavan-3-ol and galloyl moieties in the interaction of (-)-epigallocatechin gallate with serum albumin.
Topics: Animals; Catechin; Cattle; Flavonoids; Kinetics; Molecular Structure; Protein Binding; Serum Albumin | 2014 |
Astringency is a trigeminal sensation that involves the activation of G protein-coupled signaling by phenolic compounds.
Topics: Adult; Aged; Animals; Astringents; Calcium; Catechin; Chorda Tympani Nerve; GTP-Binding Proteins; Humans; Mice; Middle Aged; Phenols; Polyphenols; Signal Transduction; Taste; Taste Perception; Transient Receptor Potential Channels; Trigeminal Ganglion; Wine | 2014 |
Increased STAT1 signaling in endocrine-resistant breast cancer.
Topics: Blotting, Western; Breast Neoplasms; Catechin; Cell Survival; Cyclic S-Oxides; Estrogens; Female; Humans; MCF-7 Cells; Polymerase Chain Reaction; Pyridines; STAT1 Transcription Factor; STAT3 Transcription Factor; Tamoxifen; Tyrphostins | 2014 |
The green tea extract epigallocatechin-3-gallate inhibits irradiation-induced pulmonary fibrosis in adult rats.
Topics: Actins; Animals; Antioxidants; Catechin; Dexamethasone; Gamma Rays; Gene Expression; Heme Oxygenase-1; Hydroxyproline; Injections, Intraperitoneal; Interleukin-10; Interleukin-6; Lung; Male; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Pulmonary Fibrosis; Pulmonary Surfactant-Associated Protein B; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Tea; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2014 |
Inhibition enhancer of zeste homologue 2 promotes senescence and apoptosis induced by doxorubicin in p53 mutant gastric cancer cells.
Topics: Apoptosis; Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Cellular Senescence; DNA Damage; Down-Regulation; Doxorubicin; Enhancer of Zeste Homolog 2 Protein; Humans; Mutation; Polycomb Repressive Complex 2; RNA Interference; RNA, Small Interfering; Stomach Neoplasms; Tumor Suppressor Protein p53 | 2014 |
Exploring the influence of EGCG on the β-sheet-rich oligomers of human islet amyloid polypeptide (hIAPP1-37) and identifying its possible binding sites from molecular dynamics simulation.
Topics: Algorithms; Binding Sites; Catechin; Humans; Islet Amyloid Polypeptide; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Protein Conformation; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary | 2014 |
Fabrication of coated bovine serum albumin (BSA)-epigallocatechin gallate (EGCG) nanoparticles and their transport across monolayers of human intestinal epithelial Caco-2 cells.
Topics: Biological Availability; Biological Transport; Caco-2 Cells; Catechin; Chitosan; Coated Materials, Biocompatible; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestines; Nanoparticles; Particle Size; Peptide Hydrolases; Polylysine; Serum Albumin, Bovine | 2014 |
Detection of the polyphenolic components in Ribes nigrum L.
Topics: Antioxidants; Catechin; Chromatography, High Pressure Liquid; Polyphenols; Reproducibility of Results; Ribes; Romania; Spectrophotometry, Ultraviolet | 2014 |
Towards the discovery of drug-like epigallocatechin gallate analogs as Hsp90 inhibitors.
Topics: Biological Products; Catechin; Drug Discovery; HSP90 Heat-Shock Proteins; Structure-Activity Relationship | 2014 |
Epigallocatechin gallate (EGCG) attenuates infrasound-induced neuronal impairment by inhibiting microglia-mediated inflammation.
Topics: Animals; Apoptosis; Catechin; Culture Media, Conditioned; Cytokines; Inflammation; Inflammation Mediators; Male; Microglia; Neurons; Neuroprotective Agents; NF-kappa B; Rats, Sprague-Dawley; Sound | 2014 |
Cellular uptake and cytotoxicity of chitosan-caseinophosphopeptides nanocomplexes loaded with epigallocatechin gallate.
Topics: Biological Transport; Caco-2 Cells; Caseins; Catechin; Cell Survival; Chitosan; Hep G2 Cells; Humans; Nanoparticles; Particle Size; Phosphopeptides | 2012 |
Epigallocatechin gallate promotes the development of mouse 2-cell embryos in vitro by regulating mitochondrial activity and expression of genes related to p53 signalling pathway.
Topics: Animals; Apoptosis; Catechin; Cell Cycle; Cells, Cultured; Female; Free Radical Scavengers; Gene Expression Regulation; In Vitro Techniques; Male; Membrane Potential, Mitochondrial; Mice; Mitochondria; Reactive Oxygen Species; Signal Transduction; Tumor Suppressor Protein p53 | 2014 |
Epigallocatechin-3-gallate (EGCG)-stabilized selenium nanoparticles coated with Tet-1 peptide to reduce amyloid-β aggregation and cytotoxicity.
Topics: Amyloid beta-Peptides; Animals; Catechin; Cell Survival; Metal Nanoparticles; PC12 Cells; Rats; Selenium | 2014 |
Epigallocatechin gallate suppresses LPS endocytosis and nitric oxide production by reducing Rab5-caveolin-1 interaction.
Topics: Animals; Catechin; Caveolin 1; Cell Line; Endocytosis; Humans; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Protein Binding; rab5 GTP-Binding Proteins | 2014 |
In vitro anti-osteoporosis properties of diverse Korean Drynariae rhizoma phenolic extracts.
Topics: Animals; Antioxidants; Catechin; Cell Proliferation; Cells, Cultured; Chlorogenic Acid; Chromatography, High Pressure Liquid; Coumaric Acids; Emodin; Hydroxybenzoates; Luteolin; Mice; Osteoporosis; Phloroglucinol; Plant Extracts; Plants, Medicinal; Polypodiaceae; Quercetin; Republic of Korea | 2014 |
Recombinant expression and inhibition mechanism analysis of pectin methylesterase from Aspergillus flavus.
Topics: Aspergillus flavus; Carboxylic Ester Hydrolases; Catechin; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Enzyme Stability; Gene Expression; Hydrogen-Ion Concentration; Models, Molecular; Molecular Docking Simulation; Molecular Weight; Pichia; Protein Conformation; Recombinant Proteins; Temperature | 2014 |
Epigallocatechin gallate induces the steady state mRNA levels of pS2 and PR genes in MCF-7 breast cancer cells.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Catechin; Cell Survival; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Receptors, Progesterone; RNA, Messenger; Trefoil Factor-1; Tumor Suppressor Proteins | 2014 |
[Epigallocatechin gallate attenuates the expression of regulated upon activation normal T cell expressed and secreted induced by lipopolysaccharide in human retinal endothelial cells].
Topics: Catechin; Cells, Cultured; Chemokine CCL5; Endothelial Cells; Humans; Lipopolysaccharides; Phosphorylation; Proto-Oncogene Proteins c-akt; Retina | 2014 |
[Assessment of inner filter effect corrections in fluorimetry of the interaction between polyphenols and proteins].
Topics: Catechin; Elapid Venoms; Fluorometry; Fruit; Phospholipases A2; Polyphenols | 2014 |
Red wine tannins fluidify and precipitate lipid liposomes and bicelles. A role for lipids in wine tasting?
Topics: Catechin; Humans; Liposomes; Magnetic Resonance Spectroscopy; Tannins; Taste; Wine | 2014 |
A small molecule inhibits virion attachment to heparan sulfate- or sialic acid-containing glycans.
Topics: Animals; Antiviral Agents; Catechin; Chlorocebus aethiops; DNA Viruses; Dogs; Heparitin Sulfate; Madin Darby Canine Kidney Cells; N-Acetylneuraminic Acid; Polysaccharides; RNA Viruses; Vero Cells; Virion; Virus Attachment | 2014 |
(-)-Epigallocatechin gallate protects against cerebral ischemia-induced oxidative stress via Nrf2/ARE signaling.
Topics: Animals; Antioxidant Response Elements; Brain Ischemia; Catechin; Male; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction | 2014 |
Ferulic acid enhances the vasorelaxant effect of epigallocatechin gallate in tumor necrosis factor-alpha-induced inflammatory rat aorta.
Topics: Animals; Aorta; Arginine; Catechin; Coumaric Acids; Dipeptides; Drug Synergism; Male; Rats, Sprague-Dawley; Structure-Activity Relationship; Tumor Necrosis Factor-alpha; Vasodilation | 2014 |
(-)-Epigallocatechin-3-gallate attenuated myocardial mitochondrial dysfunction and autophagy in diabetic Goto-Kakizaki rats.
Topics: Animals; Autophagy; Catechin; Diabetes Mellitus, Experimental; Disease Models, Animal; Male; Mitochondria, Heart; Oxidative Stress; Rats; Rats, Wistar | 2014 |
Copolymeric micelles for delivery of EGCG and cyclopamine to pancreatic cancer cells.
Topics: Apoptosis; Catechin; Cell Line, Tumor; Down-Regulation; Drug Delivery Systems; ErbB Receptors; Hedgehog Proteins; Humans; Micelles; Pancreatic Neoplasms; Phosphorylation; Polyesters; Polyethylene Glycols; Polymers; Signal Transduction; Veratrum Alkaloids | 2014 |
Regulation of p53-targeting microRNAs by polycyclic aromatic hydrocarbons: Implications in the etiology of multiple myeloma.
Topics: 3' Untranslated Regions; Benzo(a)pyrene; Carcinogens, Environmental; Catechin; Cell Line, Tumor; Cell Survival; Down-Regulation; HeLa Cells; Humans; MicroRNAs; Multiple Myeloma; Polycyclic Aromatic Hydrocarbons; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; Tumor Suppressor Protein p53; Up-Regulation | 2015 |
The batch adsorption of the epigallocatechin gallate onto apple pomace.
Topics: Catechin; Fruit; Malus; Thermodynamics | 2014 |
A short-term preservation of human cultured periosteal sheets, osteogenic grafting materials, using a commercial preservation solution containing epigallocatechin-3-gallate (Theliokeep(®)) under hypothermic conditions.
Topics: Catechin; Cell Survival; Collagen; Humans; Organ Preservation; Organ Preservation Solutions; Periosteum; Tissue Culture Techniques | 2012 |
Partial cloning, tissue distribution and effects of epigallocatechin gallate on hepatic 3-hydroxy-3-methylglutaryl-CoA reductase mRNA transcripts in goldfish (Carassius auratus).
Topics: Amino Acid Sequence; Animals; Base Sequence; Catechin; Cloning, Molecular; Gene Expression Regulation; Goldfish; Hydroxymethylglutaryl CoA Reductases; Liver; Molecular Sequence Data; Organ Specificity; Phylogeny; RNA, Messenger; Sequence Alignment | 2014 |
Salivary α-amylase, serum albumin, and myoglobin protect against DNA-damaging activities of ingested dietary agents in vitro.
Topics: Catechin; Cell Line, Tumor; Coffea; Comet Assay; Diet; DNA Damage; Gallic Acid; HeLa Cells; Humans; Myoglobin; Polyphenols; Protective Agents; Pyrogallol; Salivary alpha-Amylases; Serum Albumin; Tea | 2014 |
EGCG mediated downregulation of NF-AT and macrophage infiltration in experimental hepatic steatosis.
Topics: Animals; Antioxidants; Catechin; Cell Adhesion Molecules; Cholesterol, Dietary; Down-Regulation; Drug Evaluation, Preclinical; Fatty Liver; Liver; Macrophages; Male; NF-kappa B; NFATC Transcription Factors; Phytotherapy; Plant Extracts; Rats, Wistar; Tumor Necrosis Factor-alpha | 2014 |
Catechins inhibit vascular endothelial growth factor production and cyclooxygenase-2 expression in human dental pulp cells.
Topics: Blotting, Western; Catechin; Cells, Cultured; Cyclooxygenase 2 Inhibitors; Dental Pulp; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Humans; Interleukin-1beta; Lipopolysaccharides; Peptidoglycan; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2015 |
Green tea polyphenol epigallocatechin-3-gallate inhibits TNF-α-induced production of monocyte chemoattractant protein-1 in human umbilical vein endothelial cells.
Topics: Catechin; Cell Survival; Cells, Cultured; Chemokine CCL2; Dose-Response Relationship, Drug; Human Umbilical Vein Endothelial Cells; Humans; RNA, Messenger; Structure-Activity Relationship; Tea; Tumor Necrosis Factor-alpha | 2014 |
The effect of epigallocatechin gallate on hepatocytes isolated from normal and partially hepatectomized rats.
Topics: Animals; Antioxidants; Caspase 3; Caspase 7; Catechin; Cell Survival; DNA; Dose-Response Relationship, Drug; Hepatectomy; Hepatocytes; Male; Oxidative Stress; Primary Cell Culture; Rats; Rats, Wistar | 2014 |
Improving anticancer efficacy of (-)-epigallocatechin-3-gallate gold nanoparticles in murine B16F10 melanoma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Gold; Humans; Male; Melanoma, Experimental; Metal Nanoparticles; Mice; Mice, Inbred C57BL | 2014 |
Enhanced uptake and transport of (+)-catechin and (-)-epigallocatechin gallate in niosomal formulation by human intestinal Caco-2 cells.
Topics: Caco-2 Cells; Catechin; Humans; Intestinal Absorption; Liposomes; Metabolic Clearance Rate; Nanocapsules; Up-Regulation | 2014 |
Differential activities of fungi-derived tannases on biotransformation and substrate inhibition in green tea extract.
Topics: Antioxidants; Biocatalysis; Biotransformation; Carboxylic Ester Hydrolases; Catechin; Free Radical Scavengers; Fungi; Gallic Acid; Hydrolysis; Plant Extracts; Polyphenols; Tea | 2014 |
Biochemical characterization of Aspergillus oryzae native tannase and the recombinant enzyme expressed in Pichia pastoris.
Topics: Aspergillus oryzae; Carboxylic Ester Hydrolases; Catechin; Electrophoresis, Polyacrylamide Gel; Fungal Proteins; Gene Expression; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; Pichia; Protein Subunits; Recombinant Proteins; Substrate Specificity | 2014 |
Concentrated green tea extract induces severe acute hepatitis in a 63-year-old woman--a case report with pharmaceutical analysis.
Topics: Acute Disease; Camellia sinensis; Catechin; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Dietary Supplements; Female; Humans; Middle Aged; Plant Extracts; Severity of Illness Index; Tea | 2014 |
Antifibrotic properties of epigallocatechin-3-gallate in endometriosis.
Topics: Acetylcysteine; Actins; Adult; Animals; Catechin; Cell Movement; Cell Proliferation; Cells, Cultured; Connective Tissue Growth Factor; Endometriosis; Female; Fibronectins; Fibrosis; Humans; Matrix Metalloproteinase 2; Mice; Mice, Nude; Peptide Fragments; Signal Transduction | 2014 |
Mechanistic studies for tri-targeted inhibition of enzymes involved in cholesterol biosynthesis by green tea polyphenols.
Topics: Animals; Carboxy-Lyases; Catechin; Cholesterol; Enzyme Inhibitors; Geranyltranstransferase; Humans; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; Phosphotransferases (Alcohol Group Acceptor); Rats; Tea | 2014 |
Epigallocatechin-3-gallate inhibits proliferation of human aortic smooth muscle cells via up-regulating expression of mitofusin 2.
Topics: Aorta; Catechin; Cell Line; Cell Proliferation; GTP Phosphohydrolases; Humans; Mitochondrial Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Smooth Muscle; Proto-Oncogene Proteins c-raf; RNA, Small Interfering; Up-Regulation | 2014 |
Properties of precipitate of creaming down by (-)-epigallocatechin-3-O-gallate and caffeine.
Topics: Caffeine; Catechin; Chemical Precipitation; Models, Molecular; Molecular Structure | 2014 |
Green tea polyphenol, epigallocatechin-3-gallate, possesses the antiviral activity necessary to fight against the hepatitis B virus replication in vitro.
Topics: Antiviral Agents; Camellia sinensis; Catechin; Dose-Response Relationship, Drug; Hep G2 Cells; Hepatitis B virus; Humans; In Vitro Techniques; Plant Extracts; Virus Replication | 2014 |
How epigallocatechin gallate can inhibit α-synuclein oligomer toxicity in vitro.
Topics: alpha-Synuclein; Biopolymers; Calorimetry, Differential Scanning; Catechin; Cell Membrane Permeability; Circular Dichroism; In Vitro Techniques; Microscopy, Confocal; Microscopy, Electron, Transmission; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Secondary | 2014 |
Molecular identification for epigallocatechin-3-gallate-mediated antioxidant intervention on the H2O2-induced oxidative stress in H9c2 rat cardiomyoblasts.
Topics: Animals; Antioxidants; Apoptosis; Catechin; Cell Survival; Glycogen Synthase Kinase 3; Hydrogen Peroxide; Mitochondria; Myoblasts; Myocardium; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Rats; Reactive Oxygen Species; Signal Transduction | 2014 |
Effect of selected catechins on doxorubicin antiproliferative efficacy and hepatotoxicity in vitro.
Topics: Animals; Antineoplastic Agents; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Doxorubicin; Hepatocytes; Humans; Male; Rats; Rats, Wistar; Reactive Oxygen Species | 2014 |
In vivo human skin penetration of (-)-epigallocatechin-3-gallate from topical formulations.
Topics: Administration, Topical; Adult; Antioxidants; Catechin; Chemistry, Pharmaceutical; Drug Delivery Systems; Emulsions; Excipients; Female; Gels; Humans; Male; Permeability; Photolysis; Skin; Skin Absorption; Young Adult | 2014 |
Green tea extract inhibition of human leiomyoma cell proliferation is mediated via catechol-O-methyltransferase.
Topics: Catechin; Catechol O-Methyltransferase; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase 4; Female; Gene Expression; Gene Expression Profiling; Gene Silencing; Humans; Leiomyoma; Proliferating Cell Nuclear Antigen; RNA, Small Interfering; Signal Transduction; Tea; Uterine Neoplasms | 2014 |
Isolation and characterization of rat intestinal bacteria involved in biotransformation of (-)-epigallocatechin.
Topics: Actinobacteria; Animals; Bacteria; Biotransformation; Catechin; Feces; Lactones; Metabolic Networks and Pathways; Pentanoic Acids; Rats | 2014 |
Attenuated migration by green tea extract (-)-epigallocatechin gallate (EGCG): involvement of 67 kDa laminin receptor internalization in macrophagic cells.
Topics: Animals; Antioxidants; Catechin; Cell Line; Cell Movement; Lipopolysaccharides; Macrophages; Mice; Microscopy, Confocal; Plant Extracts; Receptors, Laminin; Tea | 2014 |
Excellent anti-proliferative and pro-apoptotic effects of (-)-epigallocatechin-3-gallate encapsulated in chitosan nanoparticles on human melanoma cell growth both in vitro and in vivo.
Topics: Animals; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Chitosan; Humans; Male; Melanoma; Mice; Mice, Nude; Nanoparticles; Nanotechnology; Xenograft Model Antitumor Assays | 2014 |
EGCG inhibits the growth and tumorigenicity of nasopharyngeal tumor-initiating cells through attenuation of STAT3 activation.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplastic Stem Cells; Signal Transduction; Spheroids, Cellular; STAT3 Transcription Factor; Time Factors | 2014 |
Epigallocatechin-3-gallate (EGCG) protects skin cells from ionizing radiation via heme oxygenase-1 (HO-1) overexpression.
Topics: Antioxidants; Apoptosis; Catechin; Cell Line; Cell Survival; Gene Knockdown Techniques; Heme Oxygenase-1; Histones; Humans; Keratinocytes; Radiation Tolerance; Radiation-Protective Agents; Reactive Oxygen Species; Transcriptional Activation | 2014 |
In vitro activity of curcumin in combination with epigallocatechin gallate (EGCG) versus multidrug-resistant Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Catechin; Colony Count, Microbial; Curcumin; Drug Resistance, Multiple, Bacterial; Drug Synergism; Microbial Sensitivity Tests; Microbial Viability | 2014 |
Anacardic acid from brazilian cashew nut trees reduces dentine erosion.
Topics: Anacardic Acids; Anacardium; Animals; Antioxidants; Cariostatic Agents; Catechin; Cattle; Dentin; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Microscopy, Electron, Scanning; Nuts; Phytotherapy; Plant Extracts; Sodium Fluoride; Tooth Demineralization; Tooth Erosion; Tooth Remineralization; Tooth Root | 2014 |
Interactions of epigallo-catechin 3-gallate and ovalbumin, the major allergen of egg white.
Topics: Allergens; Antigen-Presenting Cells; Basophils; Catechin; Circular Dichroism; Egg White; Electrophoresis, Polyacrylamide Gel; Food Hypersensitivity; Humans; Immunoglobulin E; Monocytes; Ovalbumin; Polyphenols; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Tea | 2014 |
Free energy predictions of ligand binding to an α-helix using steered molecular dynamics and umbrella sampling simulations.
Topics: Catechin; Keratins; Ligands; Molecular Dynamics Simulation; Protein Binding; Protein Stability; Protein Structure, Secondary; Thermodynamics | 2014 |
Voluntary wheel running, but not a diet containing (-)-epigallocatechin-3-gallate and β-alanine, improves learning, memory and hippocampal neurogenesis in aged mice.
Topics: Aging; Animals; beta-Alanine; Brain; Brain-Derived Neurotrophic Factor; Catechin; Conditioning, Psychological; Fear; Gene Expression; Interleukin-1beta; Male; Maze Learning; Memory; Mice, Inbred BALB C; Motor Activity; Neurogenesis; Oxidative Stress; Running; Volition | 2014 |
The application of (-)-epigallocatechin gallate in preparation of an antioxidant dialysate.
Topics: Antioxidants; Catechin; Hemodialysis Solutions; Humans; Oxidation-Reduction; Oxidative Stress; Polyphenols | 2012 |
Antioxidative effect of epigallocatechin gallate against D-galactosamine-induced injury in primary culture of rat hepatocytes.
Topics: Animals; Antioxidants; Catechin; Cell Culture Techniques; Galactosamine; Glutathione; Hepatocytes; Rats | 2014 |
Green tea extract suppresses N-methyl-N-nitrosourea-induced photoreceptor apoptosis in Sprague-Dawley rats.
Topics: Administration, Oral; Alkylating Agents; Animals; Apoptosis; Catechin; Chromatography, Liquid; Cyclic Nucleotide Phosphodiesterases, Type 6; Female; In Situ Nick-End Labeling; Injections, Intraperitoneal; Methylnitrosourea; Photoreceptor Cells, Vertebrate; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Retinal Degeneration; Rhodopsin; Tandem Mass Spectrometry; Tea | 2014 |
A RXR ligand 6-OH-11-O-hydroxyphenanthrene with antitumour properties enhances (-)-epigallocatechin-3-gallate activity in three human breast carcinoma cell lines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Catechin; Cell Proliferation; Female; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; Ligands; MCF-7 Cells; Phenanthrenes; Retinoid X Receptors | 2014 |
Changes in the physiology and gene expression of Microcystis aeruginosa under EGCG stress.
Topics: Anti-Bacterial Agents; Catechin; Gene Expression Regulation, Bacterial; Microcystis; Oxidative Stress; Photosynthesis; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction | 2014 |
Effect of (-)-epigallocatechin gallate on the fibrillation of human serum albumin.
Topics: Catechin; Humans; Models, Molecular; Protein Binding; Protein Conformation; Serum Albumin; Tea | 2014 |
HSPA5 is an essential host factor for Ebola virus infection.
Topics: Animals; Antiviral Agents; Catechin; Ebolavirus; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Hemorrhagic Fever, Ebola; Host-Pathogen Interactions; Humans; Mice, Inbred C57BL; Virus Replication | 2014 |
(-)-Epigallocatechin-3-gallate modulates spinal cord neuronal degeneration by enhancing growth-associated protein 43, B-cell lymphoma 2, and decreasing B-cell lymphoma 2-associated x protein expression after sciatic nerve crush injury.
Topics: Animals; bcl-X Protein; Catechin; Disease Models, Animal; GAP-43 Protein; Immunohistochemistry; Male; Nerve Crush; Nerve Degeneration; Neuroprotective Agents; Peripheral Nerve Injuries; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Recovery of Function; Reverse Transcriptase Polymerase Chain Reaction; Sciatic Nerve; Spinal Cord | 2015 |
Inhibition of catalase by tea catechins in free and cellular state: a biophysical approach.
Topics: Catalase; Catechin; Cell Survival; Drug Evaluation, Preclinical; Humans; Hydrogen Peroxide; Inhibitory Concentration 50; K562 Cells; Protein Binding; Tea; Thermodynamics | 2014 |
Amelioration of lipid profile and level of antioxidant activities by epigallocatechin-gallate in a rat model of atherogenesis.
Topics: Animals; Antioxidants; Atherosclerosis; Catechin; Diet, Atherogenic; Disease Models, Animal; Lipids; Male; Rats; Rats, Wistar | 2014 |
Epigallocatechin-3-gallate and tetracycline differently affect ataxin-3 fibrillogenesis and reduce toxicity in spinocerebellar ataxia type 3 model.
Topics: Amyloid; Animals; Ataxin-3; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Catechin; Cell Survival; Chlorocebus aethiops; COS Cells; Disease Models, Animal; Gene Expression; Green Fluorescent Proteins; Humans; Hydrogen Bonding; Machado-Joseph Disease; Microscopy, Atomic Force; Nerve Tissue Proteins; Neuroprotective Agents; Protein Aggregates; Recombinant Fusion Proteins; Spectroscopy, Fourier Transform Infrared; Tetracycline | 2014 |
Purification and characterization of a novel O-methyltransferase from Flammulina velutipes.
Topics: Amino Acid Sequence; Catechin; Flammulina; Hydrogen-Ion Concentration; Methyltransferases; Molecular Sequence Data; Sequence Analysis; Temperature | 2014 |
Epigallocatechin-3-gallate suppresses the lipid deposition through the apoptosis during differentiation in bovine bone marrow mesenchymal stem cells.
Topics: Adipogenesis; Animals; Apoptosis; Bone Marrow Cells; Catechin; Cattle; CCAAT-Enhancer-Binding Protein-alpha; Cells, Cultured; Fatty Acid-Binding Proteins; Mesenchymal Stem Cells; PPAR gamma; Stearoyl-CoA Desaturase | 2015 |
Effects of epigallocatechin-3-gallate on the healing of extraction sockets with a periapical lesion: A pilot study in dogs.
Topics: Animals; Bone Regeneration; Bone Substitutes; Catechin; Cattle; Dogs; Male; Orbit; Pilot Projects | 2015 |
Zinc ionophore activity of quercetin and epigallocatechin-gallate: from Hepa 1-6 cells to a liposome model.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Antioxidants; Biological Transport; Catechin; Cell Line, Tumor; Cell Membrane Permeability; Cholesterol; Clioquinol; Cytoplasm; Fluorescent Dyes; Hepatocytes; Ionophores; Mice; Microscopy, Fluorescence; Osmolar Concentration; Polycyclic Compounds; Quercetin; Unilamellar Liposomes; Zinc | 2014 |
Quercetin, luteolin, and epigallocatechin gallate promote glucose disposal in adipocytes with regulation of AMP-activated kinase and/or sirtuin 1 activity.
Topics: 3T3-L1 Cells; Adipocytes; Adipokines; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Catechin; Glucose; Hypoglycemic Agents; Insulin; Luteolin; Mice; NF-kappa B; Niacinamide; Phosphorylation; Plant Extracts; Proto-Oncogene Proteins c-akt; Quercetin; Signal Transduction; Sirtuin 1 | 2014 |
(-)-Epigallocatechin gallate selectively inhibits adenosine diphosphate‑stimulated human platelet activation: suppression of heat shock protein 27 phosphorylation via p38 mitogen‑activated protein kinase.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Catechin; CD40 Ligand; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; Molecular Chaperones; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet-Derived Growth Factor; Ristocetin; Tea | 2014 |
Acetylated FoxO1 mediates high-glucose induced autophagy in H9c2 cardiomyoblasts: regulation by a polyphenol -(-)-epigallocatechin-3-gallate.
Topics: Acetylation; Animals; Antioxidants; Autophagy; Biomarkers; Catechin; Cell Line; Cytosol; Forkhead Transcription Factors; Glucose; Insulin Resistance; Male; Myoblasts, Cardiac; Nerve Tissue Proteins; Polyphenols; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species | 2014 |
Membrane lipids protected from oxidation by red wine tannins: a proton NMR study.
Topics: Antioxidants; Catechin; Chlorobenzenes; Dimyristoylphosphatidylcholine; Dose-Response Relationship, Drug; Kinetics; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Lipids; Molecular Dynamics Simulation; Molecular Structure; Oxidation-Reduction; Phosphatidylcholines; Time Factors; Wine | 2014 |
Augmented cellular uptake of nanoparticles using tea catechins: effect of surface modification on nanoparticle-cell interaction.
Topics: Animals; Camellia sinensis; Catechin; Cell Line; Cell Line, Tumor; Coated Materials, Biocompatible; Diffusion; Glioma; Humans; Magnetite Nanoparticles; Materials Testing; Nanocapsules; Particle Size; Plant Extracts; Rats; Surface Properties | 2014 |
Effect of processing on physicochemical characteristics and bioefficacy of β-lactoglobulin-epigallocatechin-3-gallate complexes.
Topics: Caco-2 Cells; Catechin; Cell Proliferation; Chemistry, Pharmaceutical; Drug Stability; Hot Temperature; Humans; Lactoglobulins; Nanoparticles; Particle Size; Surface Tension | 2014 |
Effect of dietary supplementation of (-)-epigallocatechin gallate on gut microbiota and biomarkers of colonic fermentation in rats.
Topics: Acetic Acid; Animals; Bifidobacterium; Biomarkers; Butyric Acid; Catechin; Clostridium; Cresols; Dietary Supplements; Feces; Fermentation; Gastrointestinal Tract; Male; Microbiota; Organ Size; Prevotella; Rats; Rats, Wistar; Weight Gain | 2014 |
Theobromine enhances absorption of cacao polyphenol in rats.
Topics: Administration, Oral; Animals; Area Under Curve; Cacao; Catechin; Male; Plant Extracts; Polyphenols; Rats; Rats, Wistar; Theobromine | 2014 |
Green tea extract treatment alleviates ocular inflammation in a rat model of endotoxin-induced uveitis.
Topics: Animals; Aqueous Humor; Catechin; Disease Models, Animal; Endotoxins; Inflammation; Lipopolysaccharides; Neutrophil Infiltration; Plant Extracts; Rats; Rats, Sprague-Dawley; Tea; Uveitis | 2014 |
Structure-activity studies of (-)-epigallocatechin gallate derivatives as HCV entry inhibitors.
Topics: Antiviral Agents; Catechin; Cell Survival; Dose-Response Relationship, Drug; Hepacivirus; Humans; Microbial Sensitivity Tests; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured; Virus Internalization | 2014 |
Epigallocatechin-3-gallate-mediated Tollip induction through the 67-kDa laminin receptor negatively regulating TLR4 signaling in endothelial cells.
Topics: Animals; Catechin; Cell Adhesion Molecules; Endothelial Cells; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Receptors, Laminin; RNA Interference; RNA, Small Interfering; Signal Transduction; Toll-Like Receptor 4 | 2014 |
A combination of eicosapentaenoic acid-free fatty acid, epigallocatechin-3-gallate and proanthocyanidins has a strong effect on mTOR signaling in colorectal cancer cells.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin D1; Eicosapentaenoic Acid; Grape Seed Extract; Humans; Proanthocyanidins; Proto-Oncogene Proteins c-myc; Signal Transduction; TOR Serine-Threonine Kinases | 2014 |
Epigalloccatechin-3-gallate inhibits ocular neovascularization and vascular permeability in human retinal pigment epithelial and human retinal microvascular endothelial cells via suppression of MMP-9 and VEGF activation.
Topics: Animals; Camellia sinensis; Capillary Permeability; Catechin; Cornea; Endothelial Cells; Extracellular Matrix; Humans; Matrix Metalloproteinase 9; Mice; Neovascularization, Physiologic; Platelet Endothelial Cell Adhesion Molecule-1; Reactive Oxygen Species; Retinal Pigment Epithelium; Signal Transduction; Vascular Endothelial Growth Factor A | 2014 |
Epigallocatechin-3-gallate functions as a physiological regulator by modulating the jasmonic acid pathway.
Topics: Arabidopsis; Arabidopsis Proteins; Botrytis; Catechin; Cyclopentanes; Disease Susceptibility; Flavonoids; Gene Expression Regulation, Plant; Oxylipins; Plant Diseases; Plant Growth Regulators; Salicylic Acid; Signal Transduction | 2015 |
The therapeutic effects of EGCG on vitiligo.
Topics: Animals; Anti-Inflammatory Agents; Catechin; CD8-Positive T-Lymphocytes; Disease Models, Animal; Female; Hydroquinones; Interferon-gamma; Interleukin-6; Melanocytes; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Skin Pigmentation; Transcriptome; Tumor Necrosis Factor-alpha; Vitiligo | 2014 |
The effect of (-)-epigallocatechin 3-O--gallate in vitro and in vivo in Leishmania braziliensis: involvement of reactive oxygen species as a mechanism of action.
Topics: Animals; Antioxidants; Catechin; Leishmania braziliensis; Leishmaniasis; Mice; Mice, Inbred BALB C; Reactive Oxygen Species | 2014 |
Tea component, epigallocatechin gallate, potentiates anticataleptic and locomotor-sensitizing effects of caffeine in mice.
Topics: Animals; Antipsychotic Agents; Caffeine; Catalepsy; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Lipid Peroxidation; Male; Mice; Motor Activity; Parkinsonian Disorders; Tea | 2015 |
Immunomodulatory effects of EGCG fraction of green tea extract in innate and adaptive immunity via T regulatory cells in murine model.
Topics: Adaptive Immunity; Animals; B-Lymphocytes; Catechin; Cell Proliferation; Female; Immunity, Innate; Killer Cells, Natural; Mice; Mice, Inbred BALB C; Ovalbumin; Phagocytes; Phagocytosis; Plant Extracts; T-Lymphocytes, Regulatory; Tea | 2014 |
Assessment of extraction parameters on antioxidant capacity, polyphenol content, epigallocatechin gallate (EGCG), epicatechin gallate (ECG) and iriflophenone 3-C-β-glucoside of agarwood (Aquilaria crassna) young leaves.
Topics: Catechin; Ethanol; Flavonoids; Free Radical Scavengers; Glucosides; Plant Extracts; Plant Leaves; Polyphenols; Solid Phase Extraction; Solvents; Thymelaeaceae | 2014 |
Protective effects of epigallocatechin gallate (EGCG) on streptozotocin-induced diabetic nephropathy in mice.
Topics: Animals; Blotting, Western; Body Weight; Catechin; Diabetic Nephropathies; Immunohistochemistry; Male; Mice; Mice, Inbred ICR; Random Allocation; Streptozocin | 2014 |
Tea derived galloylated polyphenols cross-link purified gastrointestinal mucins.
Topics: Animals; Catechin; Cross-Linking Reagents; Elasticity; Gastrointestinal Tract; Humans; Mucins; Neutron Diffraction; Phase Transition; Phenols; Polyphenols; Scattering, Small Angle; Solutions; Swine; Tea; Viscosity | 2014 |
Binding of (-)-epigallocatechin-3-gallate with thermally-induced bovine serum albumin/ι-carrageenan particles.
Topics: Animals; Antioxidants; Carrageenan; Catechin; Cattle; Circular Dichroism; Fluorescence; Hydrophobic and Hydrophilic Interactions; Particle Size; Protein Binding; Protein Structure, Secondary; Serum Albumin, Bovine; Spectrometry, Fluorescence; Surface Tension; Temperature | 2015 |
EGCG inhibits properties of glioma stem-like cells and synergizes with temozolomide through downregulation of P-glycoprotein inhibition.
Topics: Aldehyde Dehydrogenase 1 Family; Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Catechin; Cell Line, Tumor; Cell Movement; Cell Survival; Dacarbazine; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Glioma; Humans; Isoenzymes; Neoplastic Stem Cells; Rats; Retinal Dehydrogenase; RNA, Messenger; Temozolomide | 2015 |
Effects of antioxidants and additional emulsifiers on the stability of emulsified milk fat in the photo/radical oxidation system.
Topics: Animals; Antioxidants; Catechin; Emulsifying Agents; Emulsions; Fats; Milk; Oxidation-Reduction; Plant Extracts; Polysorbates; Quercetin; Tea; Tocopherols | 2014 |
Analysis of the effect of the active compound of green tea (EGCG) on the proliferation of peripheral blood mononuclear cells.
Topics: Adult; Breast Neoplasms; Camellia sinensis; Catechin; Cell Proliferation; Cells, Cultured; Female; Humans; Interferon-gamma; Leukocytes, Mononuclear; Plant Extracts | 2014 |
Validation of a high performance liquid chromatography method for the stabilization of epigallocatechin gallate.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Buffers; Catechin; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Stability; Drug Storage; Ethylene Glycols; Excipients; HEPES; Hot Temperature; Hydrogen-Ion Concentration; Oxidation-Reduction; Reducing Agents; Solvents; Spectrophotometry | 2014 |
Epigallocatechingallate inhibits migration of human uveal melanoma cells via downregulation of matrix metalloproteinase-2 activity and ERK1/2 pathway.
Topics: Catechin; Cell Line, Tumor; Cell Movement; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Melanoma; Phosphorylation; Uveal Neoplasms | 2014 |
PLGA nanofiber membranes loaded with epigallocatechin-3-O-gallate are beneficial to prevention of postsurgical adhesions.
Topics: Animals; Catechin; Lactic Acid; Male; Membranes, Artificial; Nanofibers; Partial Thromboplastin Time; Peritoneum; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protective Agents; Rats; Rats, Sprague-Dawley; Tissue Adhesions | 2014 |
Binding of flavonoids to staphylococcal enterotoxin B.
Topics: Binding Sites; Catechin; Enterotoxins; Flavonoids; Humans; Kaempferols; Molecular Docking Simulation; Molecular Structure; Monosaccharides; Receptors, Antigen, T-Cell; Spectrometry, Fluorescence | 2014 |
[Signifinace of cyclin D1 expression in CNE2 cells processed by EGCG].
Topics: Carcinoma; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms | 2014 |
Screening of alternative drugs to the tumor suppressor miR-375 in esophageal squamous cell carcinoma using the connectivity map.
Topics: Antineoplastic Agents; Apoptosis; Benzocaine; Betazole; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Chenodeoxycholic Acid; Cytotoxins; DNA Primers; Esophageal Neoplasms; Humans; In Situ Nick-End Labeling; Metformin; MicroRNAs; Nizatidine; Organophosphates; Proline; Protein Array Analysis; Real-Time Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones; Transcriptome; Transfection; Tumor Suppressor Proteins | 2014 |
Improvement of polyphenol properties upon glucosylation in a UV-induced skin cell ageing model.
Topics: Antioxidants; Biphenyl Compounds; Caffeic Acids; Catalase; Catechin; Cell Line; Cell Survival; Glycosylation; Humans; Interleukins; Picrates; Skin Aging; Superoxide Dismutase | 2014 |
Epigallocatechin-3-gallate protects against cisplatin nephrotoxicity by inhibiting the apoptosis in mouse.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Catechin; Cisplatin; Disease Models, Animal; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred C57BL | 2014 |
Mir-194 is a hepatocyte gate keeper hindering HCV entry through targeting CD81 receptor.
Topics: Catechin; Computational Biology; Flow Cytometry; Hepacivirus; Hepatitis C; Humans; Liver; Liver Transplantation; MicroRNAs; Reverse Transcriptase Polymerase Chain Reaction; Tetraspanin 28; Up-Regulation | 2015 |
Tocotrienol-rich fraction, [6]-gingerol and epigallocatechin gallate inhibit proliferation and induce apoptosis of glioma cancer cells.
Topics: Apoptosis; Catechin; Catechols; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Fatty Alcohols; Glioma; Humans; Tocotrienols | 2014 |
Effects of Oolong tea polyphenols, EGCG, and EGCG3″Me on pancreatic α-amylase activity in vitro.
Topics: alpha-Amylases; Animals; Camellia sinensis; Catechin; Enzyme Inhibitors; Gallic Acid; Kinetics; Pancreas; Plant Extracts; Polyphenols; Swine | 2014 |
2(5H)-Furanone, epigallocatechin gallate, and a citric-based disinfectant disturb quorum-sensing activity and reduce motility and biofilm formation of Campylobacter jejuni.
Topics: 4-Butyrolactone; Biofilms; Campylobacter jejuni; Catechin; Citric Acid; Disinfectants; Microbial Sensitivity Tests; Quorum Sensing | 2015 |
Simulated gastrointestinal digestion, intestinal permeation and plasma protein interaction of white, green, and black tea polyphenols.
Topics: Biological Availability; Blood Proteins; Catechin; Cholesterol; Digestion; Intestinal Mucosa; Polyphenols; Tea | 2015 |
Selected drugs that inhibit DNA methylation can preferentially kill p53 deficient cells.
Topics: Animals; Anticarcinogenic Agents; Azacitidine; Catechin; Cell Line, Tumor; Cell Proliferation; Cytidine; Decitabine; DNA Methylation; Humans; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neoplasm Transplantation; Phthalimides; Tryptophan; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2014 |
Epigallocatechin-3-gallate potentiates the effect of curcumin in inducing growth inhibition and apoptosis of resistant breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Caspases; Catechin; Cell Transformation, Neoplastic; Curcumin; Doxorubicin; Drug Combinations; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; MCF-7 Cells; Phytotherapy; Polyphenols; Signal Transduction | 2014 |
[Effects of EGCG on learning and memory ability expression level of NMDA receptor NR1 subunit protein in the brain of fatigue rats].
Topics: Animals; Catechin; Disease Models, Animal; Fatigue; Learning; Male; Memory; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2014 |
The effects of N-acetylcysteine and epigallocatechin-3-gallate on liver tissue protein oxidation and antioxidant enzyme levels after the exposure to radiofrequency radiation.
Topics: Acetylcysteine; Animals; Antioxidants; Catechin; Cell Phone; Guinea Pigs; Liver; Male; Oxidation-Reduction; Protein Carbonylation; Proteins; Radiation-Protective Agents; Radio Waves; Superoxide Dismutase | 2015 |
Vardenafil, a clinically available phosphodiesterase inhibitor, potentiates the killing effect of EGCG on CLL cells.
Topics: Catechin; Cell Line, Tumor; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Imidazoles; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasm Proteins; Phosphodiesterase 5 Inhibitors; Piperazines; Receptors, Laminin; Ribosomal Proteins; Sulfones; Triazines; Vardenafil Dihydrochloride | 2015 |
Determination of exogenous epigallocatechin gallate peracetate in mouse plasma using liquid chromatography with quadrupole time-of-flight mass spectrometry.
Topics: Animals; Catechin; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Female; Mass Spectrometry; Mice; Mice, Inbred ICR; Peracetic Acid; Plasma | 2014 |
Epigallocatechin-3-gallate elicits Ca2+ spike in MCF-7 breast cancer cells: essential role of Cav3.2 channels.
Topics: Breast Neoplasms; Calcium Channel Blockers; Calcium Channels, T-Type; Catechin; Cell Line, Tumor; Female; Humans; MCF-7 Cells; Membrane Potentials; Patch-Clamp Techniques | 2014 |
(-)-Epigallocatechin-3-gallate inhibits entry of hepatitis B virus into hepatocytes.
Topics: Antiviral Agents; Catechin; Cell Line; Hepatitis B; Hepatitis B virus; Hepatocytes; Humans; Plant Extracts; Virus Internalization; Virus Replication | 2014 |
Epigallocatechin-3-gallate sensitizes IFN-γ-stimulated CD4+ T cells to apoptosis via alternative activation of STAT1.
Topics: Animals; Apoptosis; Catechin; CD4-Positive T-Lymphocytes; Cell Line; Female; Humans; Interferon gamma Receptor; Interferon-gamma; Janus Kinase 1; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, SCID; Receptors, Interferon; Signal Transduction; Spleen; src-Family Kinases; STAT1 Transcription Factor | 2014 |
Mechanism of action of (-)-epigallocatechin-3-gallate: auto-oxidation-dependent activation of extracellular signal-regulated kinase 1/2 in Jurkat cells.
Topics: Camellia sinensis; Catalase; Catechin; Humans; Hydrogen Peroxide; Jurkat Cells; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 6; Oxidation-Reduction; Phosphorylation; Plant Extracts; Polyphenols; Superoxide Dismutase | 2014 |
Reorganisation of the salivary mucin network by dietary components: insights from green tea polyphenols.
Topics: Camellia sinensis; Catechin; Centrifugation, Zonal; Diet; Humans; Microscopy, Atomic Force; Mucin-5B; Mucins; Polyphenols; Protein Aggregates; Protein Structure, Tertiary; Saliva; Salivary Proteins and Peptides; Tea | 2014 |
The polyphenols (-)-epigallocatechin-3-gallate and luteolin synergistically inhibit TGF-β-induced myofibroblast phenotypes through RhoA and ERK inhibition.
Topics: Catechin; Cell Line; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Humans; Luteolin; Myofibroblasts; Phenotype; rhoA GTP-Binding Protein; Transforming Growth Factor beta | 2014 |
Self-assembled micellar nanocomplexes comprising green tea catechin derivatives and protein drugs for cancer therapy.
Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Drug Carriers; Humans; Mice; Mice, Nude; Micelles; Neoplasms; Trastuzumab | 2014 |
Epigallocatechin gallate potentially attenuates Fluoride induced oxidative stress mediated cardiotoxicity and dyslipidemia in rats.
Topics: Adenosine Triphosphatases; Animals; Antioxidants; Biomarkers; Body Weight; Calcium; Cardiotoxicity; Catechin; DNA Fragmentation; Drinking Behavior; Dyslipidemias; Feeding Behavior; Fluorides; Lipid Peroxidation; Lipids; Male; Membranes; Mitochondria, Heart; Myocardium; Organ Size; Oxidative Stress; Rats; Rats, Wistar | 2015 |
67-kDa laminin receptor-dependent protein phosphatase 2A (PP2A) activation elicits melanoma-specific antitumor activity overcoming drug resistance.
Topics: Animals; Blotting, Western; Catechin; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; DNA-Binding Proteins; Drug Resistance, Neoplasm; Enzyme Activation; Female; Histone Chaperones; Humans; Indoles; Melanoma; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Microscopy, Confocal; Mutation; Neurofibromin 2; Protein Phosphatase 2; Proto-Oncogene Proteins B-raf; Receptors, Laminin; RNA Interference; Sulfonamides; TOR Serine-Threonine Kinases; Transcription Factors; Xenograft Model Antitumor Assays | 2014 |
Content Variation of Catechin Markers, Total Phenolics and Caffeine in Green Tea Dietary Supplements.
Topics: Caffeine; Calibration; Catechin; Chromatography, High Pressure Liquid; Dietary Supplements; Polyphenols; Tea | 2016 |
Physicochemical characterization of epigallocatechin gallate lipid nanoparticles (EGCG-LNs) for ocular instillation.
Topics: Administration, Ophthalmic; Catechin; Cetrimonium; Cetrimonium Compounds; Drug Carriers; Humans; Lipids; Nanoparticles; Quaternary Ammonium Compounds | 2014 |
Biotransformation of catechin and extraction of active polysaccharide from green tea leaves via simultaneous treatment with tannase and pectinase.
Topics: Animals; Antioxidants; Biotransformation; Camellia sinensis; Carboxylic Ester Hydrolases; Catechin; Chromatography, High Pressure Liquid; Gallic Acid; Humans; Hydrolysis; Interleukin-6; Macrophages; Mice, Inbred BALB C; Plant Extracts; Plant Leaves; Polygalacturonase; Polysaccharides; Tea | 2015 |
Native and thermally modified protein-polyphenol coassemblies: lactoferrin-based nanoparticles and submicrometer particles as protective vehicles for (-)-epigallocatechin-3-gallate.
Topics: Catechin; Drug Carriers; Drug Stability; Hot Temperature; Hydrogen-Ion Concentration; Lactoferrin; Nanoparticles; Particle Size; Protein Binding; Protein Structure, Secondary | 2014 |
In vitro effects of prolonged exposure to quercetin and epigallocatechin gallate of the peripheral blood mononuclear cell membrane.
Topics: Antioxidants; Case-Control Studies; Catechin; Cell Membrane; Cells, Cultured; Drug Evaluation, Preclinical; Fluorescence Polarization; Glycation End Products, Advanced; Hypercholesterolemia; Leukocytes, Mononuclear; Membrane Fluidity; Membrane Potentials; Oxidative Stress; Quercetin | 2014 |
Protective effects of epigallocatechin-3 gallate on atrial electrical and structural remodeling in a rabbit rapid atrial pacing model.
Topics: Animals; Antioxidants; Atrial Remodeling; Catechin; Cytokines; Heart Atria; Male; Oxidative Stress; Rabbits | 2015 |
Beneficial effects of dietary EGCG and voluntary exercise on behavior in an Alzheimer's disease mouse model.
Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anxiety; Catechin; Cerebral Cortex; Disease Models, Animal; Drinking Water; Female; Hippocampus; Housing, Animal; Humans; Male; Maze Learning; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Nootropic Agents; Peptide Fragments | 2015 |
Inhibition of human aldehyde oxidase activity by diet-derived constituents: structural influence, enzyme-ligand interactions, and clinical relevance.
Topics: Aldehyde Oxidase; Catechin; Cytochrome P-450 Enzyme System; Diet; Enzyme Inhibitors; Food-Drug Interactions; Guanine; Humans; Ligands; Oxidation-Reduction; Quantitative Structure-Activity Relationship; Tea; Xenobiotics | 2015 |
Differential prooxidative effects of the green tea polyphenol, (-)-epigallocatechin-3-gallate, in normal and oral cancer cells are related to differences in sirtuin 3 signaling.
Topics: Antioxidants; Catechin; Cell Line, Tumor; ERRalpha Estrogen-Related Receptor; Gene Expression Regulation; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Mitochondria; Mouth Neoplasms; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Polyphenols; Reactive Oxygen Species; Receptors, Estrogen; Signal Transduction; Sirtuin 3; Superoxide Dismutase; Tea; Transcription Factors | 2015 |
Molecular mechanism of epigallocatechin-3-gallate in human esophageal squamous cell carcinoma in vitro and in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Squamous Cell; Caspase 3; Catechin; Cell Line, Tumor; Cell Proliferation; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; G1 Phase Cell Cycle Checkpoints; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Reactive Oxygen Species; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2015 |
[The effect of epigallocatechin gallate (EGCG) on the surface properties of nickel-chromium dental casting alloys after electrochemical corrosion].
Topics: Catechin; Chromium; Chromium Alloys; Corrosion; Dental Alloys; Nickel; Saliva, Artificial; Surface Properties | 2014 |
Epigallocatechin-3-gallate (EGCG) inhibits 3-hydroxy-3-methylglutaryl-CoA reductase in the presence of glycerol.
Topics: Catechin; Glycerol; Hep G2 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors | 2014 |
Single-step green synthesis and characterization of gold-conjugated polyphenol nanoparticles with antioxidant and biological activities.
Topics: Antioxidants; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Drug Stability; Flavonoids; Flavonols; Gold; Green Chemistry Technology; Humans; Metal Nanoparticles; Polyphenols; Resveratrol; Stilbenes | 2014 |
Molecular interactions between (-)-epigallocatechin gallate analogs and pancreatic lipase.
Topics: Animals; Catechin; Enzyme Activation; Hydrodynamics; Kinetics; Molecular Structure; Pancrelipase; Protein Binding; Protein Structure, Secondary; Swine; Thermodynamics | 2014 |
Alternative approaches to Hsp90 modulation for the treatment of cancer.
Topics: Animals; Antineoplastic Agents; Catechin; Drug Discovery; HSP90 Heat-Shock Proteins; Humans; Models, Molecular; Neoplasms; Novobiocin; Silybin; Silymarin | 2014 |
Epigallocatechin-3-gallate induces the apoptosis of hepatocellular carcinoma LM6 cells but not non-cancerous liver cells.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Hepatocellular; Catechin; Cell Cycle; Cell Line, Tumor; Cell Survival; Hepatocytes; Humans; Membrane Potential, Mitochondrial | 2015 |
Effect of pre- and post-combined multidoses of epigallocatechin gallate and coenzyme Q10 on cisplatin-induced oxidative stress in rat kidney.
Topics: Animals; Antineoplastic Agents; Antioxidants; Catechin; Cisplatin; Creatinine; Kidney; Kidney Diseases; Male; Micronutrients; Oxidative Stress; Oxidoreductases; Rats; Rats, Wistar; Ubiquinone; Urea | 2015 |
Phytoferritin association induced by EGCG inhibits protein degradation by proteases.
Topics: Catechin; Dietary Proteins; Dietary Supplements; Ferritins; Hydrogen-Ion Concentration; Iron, Dietary; Pepsin A; Peptide Hydrolases; Protein Conformation; Proteolysis; Trypsin | 2014 |
Epigallocatechin gallate attenuates proliferation and oxidative stress in human vascular smooth muscle cells induced by interleukin-1β via heme oxygenase-1.
Topics: Antioxidants; Atherosclerosis; Catechin; Cell Proliferation; Cells, Cultured; Enzyme Induction; Heme Oxygenase-1; Humans; Interleukin-1beta; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-E2-Related Factor 2; Oxidative Stress | 2014 |
Epigallocatechin-3-gallate attenuates impairment of learning and memory in chronic unpredictable mild stress-treated rats by restoring hippocampal autophagic flux.
Topics: Amyloid beta-Peptides; Animals; Autoantigens; Autophagy; CA1 Region, Hippocampal; Catechin; Chloroquine; Chronic Disease; Cognitive Dysfunction; Gene Expression Regulation; Male; Maze Learning; Memory; Microtubule-Associated Proteins; Neurons; Nootropic Agents; Peptide Fragments; Rats; Rats, Wistar; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Stress, Psychological; TOR Serine-Threonine Kinases | 2014 |
Protection of murine spermatogenesis against ionizing radiation-induced testicular injury by a green tea polyphenol.
Topics: Animals; Catechin; Cytoprotection; Female; Male; Mice; Mice, Inbred C57BL; Radiation Injuries; Radiation-Protective Agents; Radiation, Ionizing; Spermatogenesis; Spermatozoa; Testis | 2015 |
The fungal laccase-catalyzed oxidation of EGCG and the characterization of its products.
Topics: Anti-Infective Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Aspergillus; Biflavonoids; Camellia sinensis; Catalysis; Catechin; Laccase; Oxidation-Reduction; Plant Extracts; Polyphenols; Tea | 2015 |
Novel Epigenetic Regulation of Alpha-Synuclein Expression in Down Syndrome.
Topics: alpha-Synuclein; Animals; Catechin; Disease Models, Animal; DNA Methylation; Down Syndrome; Epigenesis, Genetic; Mice; Promoter Regions, Genetic | 2016 |
Protection of epigallocatechin gallate against degradation during in vitro digestion using apple pomace as a carrier.
Topics: Catechin; Digestion; Food Additives; Functional Food; Humans; In Vitro Techniques; Malus; Plant Extracts; Waste Products | 2014 |
Auto-oxidation products of epigallocatechin gallate activate TRPA1 and TRPV1 in sensory neurons.
Topics: Animals; Catechin; Cells, Cultured; Chickens; Chromatography, High Pressure Liquid; Dimerization; HEK293 Cells; Humans; Membrane Potentials; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Rats; Recombinant Fusion Proteins; Sensory Receptor Cells; Snakes; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Transient Receptor Potential Channels; TRPV Cation Channels | 2015 |
Epigallocatechin 3-gallate suppresses interleukin-1β-induced inflammatory responses in intervertebral disc cells in vitro and reduces radiculopathic pain in rats.
Topics: Adult; Animals; Catechin; Cells, Cultured; Female; Humans; Imidazoles; Inflammation; Interleukin-1 Receptor-Associated Kinases; Interleukin-1beta; Intervertebral Disc; Intervertebral Disc Degeneration; Male; MAP Kinase Kinase 4; Matrix Metalloproteinases; Middle Aged; Neuralgia; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pyridines; Radiculopathy; Rats; Rats, Sprague-Dawley | 2014 |
Promoting photosensitized reductive dechlorination of chlorothalonil using epigallocatechin gallate in water.
Topics: Camellia sinensis; Catechin; Environmental Restoration and Remediation; Fungicides, Industrial; Halogenation; Molecular Structure; Nitriles; Oxidation-Reduction; Photolysis; Plant Extracts; Seeds; Sunlight; Waste Products; Water; Water Pollutants, Chemical | 2014 |
The green tea polyphenol (-)-epigallocatechin gallate prevents the aggregation of tau protein into toxic oligomers at substoichiometric ratios.
Topics: Animals; Catechin; Humans; PC12 Cells; Protein Aggregation, Pathological; Rats; tau Proteins; Tea | 2015 |
Paclitaxel/epigallocatechin gallate coloaded liposome: a synergistic delivery to control the invasiveness of MDA-MB-231 breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Compounding; Drug Synergism; Female; Gene Expression; Humans; Liposomes; Mammary Glands, Human; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Paclitaxel | 2015 |
NNK-induced DNA methyltransferase 1 in lung tumorigenesis in A/J mice and inhibitory effects of (-)-epigallocatechin-3-gallate.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Bronchi; Carcinogenesis; Carcinogens; Catechin; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Lung; Lung Neoplasms; Mice, Inbred A; Neoplasm Proteins; Nitrosamines; Promoter Regions, Genetic; Respiratory Mucosa | 2015 |
Synergistic effect of curcumin on epigallocatechin gallate-induced anticancer action in PC3 prostate cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Catechin; Cell Cycle Checkpoints; Cell Division; Cell Line, Tumor; Cell Proliferation; Curcumin; Dose-Response Relationship, Drug; Drug Synergism; Humans; Male; Prostatic Neoplasms; Up-Regulation | 2015 |
The green tea catechin, epigallocatechin gallate inhibits chikungunya virus infection.
Topics: Antiviral Agents; Catechin; Chikungunya virus; Genetic Vectors; HEK293 Cells; Humans; Tea; Virus Attachment; Virus Replication | 2015 |
Sensitivity to hepatotoxicity due to epigallocatechin gallate is affected by genetic background in diversity outbred mice.
Topics: Animals; Antioxidants; Catechin; Chemical and Drug Induced Liver Injury; Chromosome Mapping; Dose-Response Relationship, Drug; Genotyping Techniques; In Situ Nick-End Labeling; Liver; Male; Mice; Phenotype; Polymorphism, Single Nucleotide; Polyphenols; Quantitative Trait Loci; Tea | 2015 |
Quercetin, luteolin and epigallocatechin gallate alleviate TXNIP and NLRP3-mediated inflammation and apoptosis with regulation of AMPK in endothelial cells.
Topics: AMP-Activated Protein Kinases; Apoptosis; Carrier Proteins; Catechin; Cell Line; Endoplasmic Reticulum Stress; Endothelial Cells; Endothelin-1; Gene Expression; Human Umbilical Vein Endothelial Cells; Humans; Inflammasomes; Inflammation; Luteolin; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Palmitic Acid; Protein Kinase Inhibitors; Quercetin | 2014 |
iTRAQ-based proteomic analysis of combination therapy with taurine, epigallocatechin gallate, and genistein on carbon tetrachloride-induced liver fibrosis in rats.
Topics: Animals; Antioxidants; Blotting, Western; Catechin; Chemical and Drug Induced Liver Injury; Chromatography, Ion Exchange; Chromatography, Liquid; Computational Biology; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Factor VII; Fibrinogen; Genistein; Glycolysis; Liver; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Protein Interaction Maps; Protein Serine-Threonine Kinases; Proteomics; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Taurine; Thioredoxins; Triose-Phosphate Isomerase | 2015 |
Antioxidant supplementation can reduce the survival costs of excess amino acid intake in honeybees.
Topics: Amino Acids, Essential; Animal Feed; Animals; Antioxidants; Bees; Catechin; Diet; Dietary Supplements; Longevity | 2014 |
(-)-Epigallocatechin-3-gallate induces cancer cell apoptosis via acetylation of amyloid precursor protein.
Topics: Acetylation; Amyloid beta-Protein Precursor; Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Catechin; Cell Line, Tumor; Epigenesis, Genetic; Flow Cytometry; Fluorescent Antibody Technique; Histone Deacetylase Inhibitors; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice; Mice, Nude; Neoplasms, Experimental; Rats; Xenograft Model Antitumor Assays | 2015 |
Epigallocatechin gallate prevents inflammation by reducing macrophage infiltration and inhibiting tumor necrosis factor-α signaling in the pancreas of rats on a high-fat diet.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Blood Glucose; Catechin; Cytokines; Diet, High-Fat; Inflammation; Inflammation Mediators; Insulin; Insulin Resistance; Islets of Langerhans; Macrophages; Male; Pancreas; Phytotherapy; Plant Extracts; Rats, Sprague-Dawley; Signal Transduction; Tumor Necrosis Factor-alpha | 2014 |
Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport.
Topics: Acetyl Coenzyme A; Animals; Antineoplastic Agents; Biological Transport; Catechin; Cell Line, Tumor; Cell Survival; Citric Acid; Citric Acid Cycle; Coumaric Acids; Glucose; Glutamine; Humans; Lipid Metabolism; Male; Mice, Nude; Mitochondria; Oxidation-Reduction; Pyruvic Acid; Sugar Alcohol Dehydrogenases; Tumor Burden; Xenograft Model Antitumor Assays | 2014 |
EGCG assisted green synthesis of ZnO nanopowders: Photodegradative, antimicrobial and antioxidant activities.
Topics: Anti-Bacterial Agents; Antioxidants; Catalysis; Catechin; Enterobacter aerogenes; Green Chemistry Technology; Metal Nanoparticles; Microbial Sensitivity Tests; Photolysis; Powders; Staphylococcus aureus; Zinc Oxide | 2015 |
Thermal degradation of green tea flavan-3-ols and formation of hetero- and homocatechin dimers in model dairy beverages.
Topics: Animals; Beverages; Catechin; Dietary Proteins; Flavonoids; Food Handling; Milk; Polyphenols; Tea | 2015 |
Fast identification of lipase inhibitors in oolong tea by using lipase functionalised Fe3O4 magnetic nanoparticles coupled with UPLC-MS/MS.
Topics: Catechin; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Lipase; Magnetite Nanoparticles; Plant Extracts; Tandem Mass Spectrometry; Tea | 2015 |
Physicochemical characterisation of β-carotene emulsion stabilised by covalent complexes of α-lactalbumin with (-)-epigallocatechin gallate or chlorogenic acid.
Topics: beta Carotene; Catechin; Chemical Phenomena; Chlorogenic Acid; Drug Stability; Emulsions; Lactalbumin; Particle Size; Spectrometry, Fluorescence | 2015 |
Noninvasive bioluminescence imaging of α-synuclein oligomerization in mouse brain using split firefly luciferase reporters.
Topics: alpha-Synuclein; Animals; Catechin; Cell Death; Cells, Cultured; Corpus Striatum; Dopaminergic Neurons; Humans; Luciferases, Firefly; Luminescent Measurements; Mice; Neuroimaging; Neuroprotective Agents; Protein Aggregates; Substantia Nigra; Tacrolimus | 2014 |
Enhancement of flavonoid ability to cross the blood-brain barrier of rats by co-administration with α-tocopherol.
Topics: 8-Hydroxy-2'-Deoxyguanosine; alpha-Tocopherol; Animals; Antioxidants; Blood-Brain Barrier; Catechin; Chromatography, High Pressure Liquid; Deoxyguanosine; Hippocampus; Male; Mass Spectrometry; Oxidative Stress; Quercetin; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rutin | 2015 |
Genipin-structured peptide-polysaccharide nanoparticles with significantly improved resistance to harsh gastrointestinal environments and their potential for oral delivery of polyphenols.
Topics: Caseins; Catechin; Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Drug Delivery Systems; Gastrointestinal Tract; Humans; Iridoids; Nanoparticles; Peptide Fragments; Polyphenols; Proteoglycans | 2014 |
The effect of Epigallocatechin-3-gallate in allergic airway inflammation.
Topics: Animals; Anti-Allergic Agents; Catechin; Humans; Inflammation; Matrix Metalloproteinase 9; Mice; p38 Mitogen-Activated Protein Kinases | 2014 |
Improving the effectiveness of (-)-epigallocatechin gallate (EGCG) against rabbit atherosclerosis by EGCG-loaded nanoparticles prepared from chitosan and polyaspartic acid.
Topics: Animals; Atherosclerosis; Biological Availability; Catechin; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Delivery Systems; Humans; Male; Nanoparticles; Particle Size; Peptides; Rabbits | 2014 |
Caloric restriction mimetics: natural/physiological pharmacological autophagy inducers.
Topics: Acetyl Coenzyme A; Anacardic Acids; Animals; Autophagy; Caloric Restriction; Catalysis; Catechin; Curcumin; Food Deprivation; Humans; Leucine; Mice; Models, Animal; Niacinamide; Plant Extracts; Resveratrol; Spermidine; Starvation; Stilbenes; Terpenes | 2014 |
(-)-Epigallocatechin-3-gallate inhibits nasopharyngeal cancer stem cell self-renewal and migration and reverses the epithelial-mesenchymal transition via NF-κB p65 inactivation.
Topics: Carrier Proteins; Catechin; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Humans; Intracellular Signaling Peptides and Proteins; Nasopharyngeal Neoplasms; Neoplasm Proteins; Neoplastic Stem Cells; NF-kappa B; Signal Transduction | 2015 |
Effects of epigallocatechin gallate on the cell-wall structure of Mycobacterial smegmatis mc²155.
Topics: Antitubercular Agents; Catechin; Cell Wall; Microbial Sensitivity Tests; Mycobacterium smegmatis | 2015 |
Tea polyphenols alleviate motor impairments, dopaminergic neuronal injury, and cerebral α-synuclein aggregation in MPTP-intoxicated parkinsonian monkeys.
Topics: alpha-Synuclein; Animals; Catechin; Cell Survival; Corpus Striatum; Dopamine; Dopaminergic Neurons; Female; Macaca fascicularis; Motor Activity; Neuroprotective Agents; Parkinsonian Disorders; Substantia Nigra | 2015 |
Overexpression of miR-126 sensitizes osteosarcoma cells to apoptosis induced by epigallocatechin-3-gallate.
Topics: Apoptosis; Bone Neoplasms; Catechin; Cell Cycle; Cell Proliferation; Drug Resistance, Neoplasm; Flow Cytometry; Humans; MicroRNAs; Osteosarcoma; Tumor Cells, Cultured | 2014 |
Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse post-traumatic osteoarthritis model.
Topics: Animals; Anti-Inflammatory Agents; Cartilage, Articular; Catechin; Chondrocytes; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Osteoarthritis; Palliative Care; Polyphenols; Tea | 2014 |
Nociceptive spinal cord neurons of laminae I-III exhibit oxidative stress damage during diabetic neuropathy which is prevented by early antioxidant treatment with epigallocatechin-gallate (EGCG).
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Catechin; Deoxyguanosine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Hyperalgesia; Immunohistochemistry; Male; Neuralgia; Neuroprotective Agents; Nociceptors; Oxidative Stress; Proto-Oncogene Proteins c-fos; Rats, Wistar; Spinal Cord; Touch | 2015 |
Effects of Epigallocatechin gallate against Enterococcus faecalis biofilm and virulence.
Topics: 2,2'-Dipyridyl; Antioxidants; Biofilms; Catechin; Enterococcus faecalis; Flow Cytometry; Microbial Sensitivity Tests; Polymerase Chain Reaction; Virulence | 2015 |
Dietary pretreatment with green tea polyphenol, (-)-epigallocatechin-3-gallate reduces the bioavailability and hepatotoxicity of subsequent oral bolus doses of (-)-epigallocatechin-3-gallate.
Topics: Administration, Oral; Alanine Transaminase; Animals; Biological Availability; Catechin; Diet; Glutathione; Liver; Male; Mice; Polyphenols; Tea | 2015 |
Mutational analysis of the ability of resveratrol to inhibit amyloid formation by islet amyloid polypeptide: critical evaluation of the importance of aromatic-inhibitor and histidine-inhibitor interactions.
Topics: Amino Acid Sequence; Amino Acids, Aromatic; Amyloid; Arginine; Benzothiazoles; Catechin; DNA Mutational Analysis; Histidine; Humans; Islet Amyloid Polypeptide; Molecular Sequence Data; Mutant Proteins; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Structure-Activity Relationship; Thiazoles | 2015 |
The allosteric binding sites of sulfotransferase 1A1.
Topics: Allosteric Site; Arylsulfotransferase; Catechin; Humans; Mefenamic Acid; Protein Binding | 2015 |
Epigallocatechin-3-gallate Sensitizes Human 786-O Renal Cell Carcinoma Cells to TRAIL-Induced Apoptosis.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Carcinoma, Renal Cell; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspases; Catechin; Cell Line, Tumor; Cell Survival; Down-Regulation; Flow Cytometry; Humans; Kidney Neoplasms; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; TNF-Related Apoptosis-Inducing Ligand | 2015 |
Potent inhibition of VEGFR-2 activation by tight binding of green tea epigallocatechin gallate and apple procyanidins to VEGF: relevance to angiogenesis.
Topics: Biflavonoids; Binding Sites; Catechin; Computer Simulation; Human Umbilical Vein Endothelial Cells; Humans; Malus; Phosphorylation; Proanthocyanidins; Signal Transduction; Tea; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2015 |
Epigallocatechin-3-gallate attenuates unilateral ureteral obstruction-induced renal interstitial fibrosis in mice.
Topics: Animals; Anti-Inflammatory Agents; Body Weight; Catechin; Cytokines; Fibrosis; Kidney; Kidney Glomerulus; Kidney Tubules; Macrophages; Male; Mice, Inbred C57BL; Organ Size; Protective Agents; Signal Transduction; Smad Proteins; Urethral Obstruction | 2015 |
Curcumin and epigallocatechin gallate inhibit the cancer stem cell phenotype via down-regulation of STAT3-NFκB signaling.
Topics: Antineoplastic Agents, Phytogenic; Catechin; Cell Movement; Curcumin; Down-Regulation; Drug Screening Assays, Antitumor; Humans; Hyaluronan Receptors; MCF-7 Cells; Neoplastic Stem Cells; NF-kappa B; Phenotype; Phosphorylation; Protein Processing, Post-Translational; Signal Transduction; STAT3 Transcription Factor | 2015 |
Gene regulation mediated by microRNAs in response to green tea polyphenol EGCG in mouse lung cancer.
Topics: Animals; Anticarcinogenic Agents; Camellia sinensis; Carcinogens; Catechin; Cell Cycle Proteins; Female; Gene Expression Regulation; Lung Neoplasms; Mice; MicroRNAs; Mitogen-Activated Protein Kinases; NF-kappa B; Nitrosamines; Polyphenols; Proto-Oncogene Proteins c-akt | 2014 |
Mechanism for the antibacterial action of epigallocatechin gallate (EGCg) on Bacillus subtilis.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacillus subtilis; Bacterial Proteins; Carrier Proteins; Catechin; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Glucose; Lipoproteins; Molecular Docking Simulation; Molecular Sequence Data; Oxygen; Spores, Bacterial | 2015 |
Divergent effect of liver X receptor agonists on prostate-specific antigen expression is dependent on androgen receptor in prostate carcinoma cells.
Topics: Benzoates; Benzylamines; Catechin; Cell Line, Tumor; Cell Proliferation; Humans; Hydrocarbons, Fluorinated; Liver X Receptors; Male; Orphan Nuclear Receptors; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Sulfonamides | 2015 |
Long non-coding RNAs expression profile in HepG2 cells reveals the potential role of long non-coding RNAs in the cholesterol metabolism.
Topics: Catechin; Cell Line, Tumor; Cholesterol; Hep G2 Cells; Humans; RNA, Long Noncoding | 2015 |
Effect of pH and metal ions on DPPH radical scavenging activity of tea.
Topics: Aluminum; Biphenyl Compounds; Catechin; Copper; Free Radical Scavengers; Hydrogen-Ion Concentration; Picrates; Plant Extracts; Tea; Zinc | 2015 |
Multiclass comparative virtual screening to identify novel Hsp90 inhibitors: a therapeutic breast cancer drug target.
Topics: Adenine; Anisoles; Antineoplastic Agents; Benzamides; Binding Sites; Breast Neoplasms; Catechin; Databases, Chemical; Drug Discovery; Female; Gene Expression; Glycine; Heterocyclic Compounds, 2-Ring; High-Throughput Screening Assays; HSP90 Heat-Shock Proteins; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Indazoles; Ligands; Molecular Docking Simulation; Protein Binding; Pyrazoles; Pyridines; Static Electricity; Structure-Activity Relationship; User-Computer Interface | 2015 |
Transient receptor potential vanilloid type 1 is vital for (-)-epigallocatechin-3-gallate mediated activation of endothelial nitric oxide synthase.
Topics: AMP-Activated Protein Kinases; Anilides; Animals; Calcium; Capsaicin; Catechin; Cell Movement; Cell Proliferation; Cell Survival; Cinnamates; Endothelial Cells; HEK293 Cells; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Signal Transduction; Tea; TRPV Cation Channels | 2015 |
Hippocampal Neuroprotection by Minocycline and Epigallo-Catechin-3-Gallate Against Cardiopulmonary Bypass-Associated Injury.
Topics: Adenosine Triphosphate; Animals; Apoptosis Inducing Factor; Brain Edema; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Cardiopulmonary Bypass; Caspase 3; Catechin; Chromatography, High Pressure Liquid; Disease Models, Animal; Hypoxia-Inducible Factor 1, alpha Subunit; Minocycline; Neuroprotective Agents; Poly Adenosine Diphosphate Ribose; Swine; Tyrosine | 2015 |
Green tea polyphenol (-)-epigallocatechin-3-gallate triggered hepatotoxicity in mice: responses of major antioxidant enzymes and the Nrf2 rescue pathway.
Topics: Alanine Transaminase; Aldehydes; Animals; Aspartate Aminotransferases; Catalase; Catechin; Chemical and Drug Induced Liver Injury; Glutathione Peroxidase; Histones; Interleukin-6; Liver; Male; Maximum Tolerated Dose; Mice; NF-E2-Related Factor 2; Superoxide Dismutase; Tea; Thioredoxin Reductase 1; Thioredoxins | 2015 |
Epigallocatechin gallate inhibits human tongue carcinoma cells via HK2‑mediated glycolysis.
Topics: Anticarcinogenic Agents; Apoptosis; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Cell Proliferation; Chemoprevention; Enzyme Activation; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Glycolysis; Hexokinase; Humans; Mitochondrial Membranes; Proto-Oncogene Proteins c-akt; Tongue Neoplasms | 2015 |
[Protective effect of epigallocatechin gallate against sperm abnormality in mice].
Topics: Animals; Catechin; Cyclophosphamide; Male; Mice; Mutagens; Random Allocation; Spermatozoa; Time Factors | 2014 |
The heat shock protein 90 inhibitor, (-)-epigallocatechin gallate, has anticancer activity in a novel human prostate cancer progression model.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Catechin; Cell Movement; Cell Proliferation; Disease Progression; HSP90 Heat-Shock Proteins; Humans; Male; Mice; Prostatic Hyperplasia; Prostatic Neoplasms; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Wound Healing; Xenograft Model Antitumor Assays | 2015 |
In vitro activity of 23 tea extractions and epigallocatechin gallate against Candida species.
Topics: Antifungal Agents; Aspergillus fumigatus; Camellia sinensis; Candida; Catechin; Microbial Sensitivity Tests; Microbial Viability; Plant Extracts | 2015 |
Small molecule inhibitors of Clostridium difficile toxin B-induced cellular damage.
Topics: Animals; Bacterial Proteins; Bacterial Toxins; Biflavonoids; Catechin; Cell Line; Cell Survival; Chlorocebus aethiops; Cholates; Clostridioides difficile; Gallic Acid; Humans; Kinetics; Necrosis; Phloretin; Protein Binding; Small Molecule Libraries; Vero Cells | 2015 |
(-)-epigallocatechin-3-gallate inhibits fibrillogenesis of chicken cystatin.
Topics: Amyloid; Animals; Catechin; Chickens; Cystatins; Molecular Docking Simulation; Mutation; Protein Binding; Protein Structure, Secondary | 2015 |
Au nanostructured surfaces for electrochemical and localized surface plasmon resonance-based monitoring of α-synuclein-small molecule interactions.
Topics: alpha-Synuclein; Biosensing Techniques; Catechin; Copper; Electrochemistry; Gold; Metal Nanoparticles; Protein Binding; Surface Plasmon Resonance; Tin Compounds | 2015 |
Epigallocatechin-3-Gallate Attenuates Oxidative Stress and Inflammation in Obstructive Nephropathy via NF-κB and Nrf2/HO-1 Signalling Pathway Regulation.
Topics: Animals; Bilirubin; Catechin; Disease Models, Animal; Electrophoretic Mobility Shift Assay; Heme Oxygenase-1; Inflammation; Kidney; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Signal Transduction; Ureteral Obstruction | 2015 |
EGCG inhibits proliferation, invasiveness and tumor growth by up-regulation of adhesion molecules, suppression of gelatinases activity, and induction of apoptosis in nasopharyngeal carcinoma cells.
Topics: Animals; Apoptosis; Cadherins; Carcinoma; Caspase 3; Catechin; Cell Adhesion Molecules; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Gelatinases; Humans; Mice; Mice, SCID; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; NF-kappa B; Signal Transduction; Spheroids, Cellular; Transplantation, Heterologous; Up-Regulation | 2015 |
Epigallocatechin gallate, ellagic acid, and rosmarinic acid perturb dNTP pools and inhibit de novo DNA synthesis and proliferation of human HL-60 promyelocytic leukemia cells: Synergism with arabinofuranosylcytosine.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Catechin; Cell Proliferation; Cinnamates; Cytarabine; Depsides; DNA; Drug Synergism; Ellagic Acid; Free Radical Scavengers; HL-60 Cells; Humans; Molecular Structure; Nucleic Acid Synthesis Inhibitors; Rosmarinic Acid; Thymine Nucleotides | 2015 |
Anti-melanogenic effects of black, green, and white tea extracts on immortalized melanocytes.
Topics: Animals; Catechin; Cell Line; Melanins; Melanocytes; Mice; Monophenol Monooxygenase; Plant Extracts; Plant Leaves; Tea | 2015 |
Green tea polyphenol epigallocatechin-3-gallate attenuates TNF-α-induced intercellular adhesion molecule-1 expression and monocyte adhesion to retinal pigment epithelial cells.
Topics: Active Transport, Cell Nucleus; Blotting, Western; Camellia sinensis; Catechin; Cell Adhesion; Cell Death; Cell Movement; Cells, Cultured; Cytokines; Humans; Inflammation Mediators; Intercellular Adhesion Molecule-1; Leukocytes; Microscopy, Confocal; Microscopy, Electron, Scanning; Monocytes; NF-kappa B; Oxidative Stress; Polyphenols; Reactive Oxygen Species; Retinal Pigment Epithelium; Tea; Tumor Necrosis Factor-alpha | 2015 |
(-)-Epigallocatechingallate induces apoptosis in B lymphoma cells via caspase-dependent pathway and Bcl-2 family protein modulation.
Topics: Antineoplastic Agents; Apoptosis; Caspases; Catechin; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Lymphoma, B-Cell; Proto-Oncogene Proteins c-bcl-2; Signal Transduction | 2015 |
Mechanism of Dose-Dependent Regulation of UBE1L by Polyphenols in Human Bronchial Epithelial Cells.
Topics: Antineoplastic Agents; Bronchi; Catechin; Cell Line; Cell Survival; Curcumin; Dose-Response Relationship, Drug; Epithelial Cells; Gene Expression Regulation; Humans; Polyphenols; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; tert-Butylhydroperoxide; Ubiquitin-Activating Enzymes | 2015 |
Sensitization to docetaxel in prostate cancer cells by green tea and quercetin.
Topics: Apoptosis; Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Docetaxel; Down-Regulation; Drug Synergism; Humans; Male; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms; Quercetin; Taxoids; Tea | 2015 |
Correction: Epigallocatechin-3-gallate attenuates impairment of learning and memory in chronic unpredictable mild stress-treated rats by restoring hippocampal autophagic flux.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Autophagy; CA1 Region, Hippocampal; Catechin; Male; Memory; Peptide Fragments; Rats; Rats, Wistar; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Stress, Psychological; TOR Serine-Threonine Kinases | 2015 |
Green tea polyphenol EGCG reverse cisplatin resistance of A549/DDP cell line through candidate genes demethylation.
Topics: Animals; Catechin; Cell Line, Tumor; Cell Proliferation; Cisplatin; DNA Methylation; Drug Resistance, Neoplasm; Genes, Neoplasm; Humans; Mice, Inbred BALB C; Mice, Nude; Polyphenols; Tea | 2015 |
Potentiation of growth inhibition and epigenetic modulation by combination of green tea polyphenol and 5-aza-2'-deoxycytidine in human breast cancer cells.
Topics: Azacitidine; Breast Neoplasms; Catechin; Cell Proliferation; Cell Survival; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; MCF-7 Cells; Plant Extracts; Random Amplified Polymorphic DNA Technique; Tea | 2015 |
(-) Epigallocatechin-3-gallate attenuates reserpine-induced orofacial dyskinesia and oxidative stress in rat striatum.
Topics: Animals; Catalase; Catechin; Corpus Striatum; Disease Models, Animal; Glutathione; Lipid Peroxidation; Male; Movement Disorders; Oxidative Stress; Rats; Rats, Wistar; Reserpine; Superoxide Dismutase | 2015 |
Molecular characterization of the boron adducts of the proteasome inhibitor bortezomib with epigallocatechin-3-gallate and related polyphenols.
Topics: Antineoplastic Agents; Bortezomib; Catalytic Domain; Catechin; Cell Line, Tumor; Cell Proliferation; Humans; Models, Molecular; Polyphenols; Proteasome Endopeptidase Complex; Proteasome Inhibitors | 2015 |
High concentration of epigallocatechin-3-gallate increased the incidences of arrhythmia and diastolic dysfunction via β2-adrenoceptor.
Topics: Animals; Arrhythmias, Cardiac; Camellia sinensis; Catechin; Glucose; Heart; Male; Muscle Contraction; Myocardium; Myocytes, Cardiac; Plant Extracts; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Tea; Tromethamine | 2015 |
Acetylproteomic analysis reveals functional implications of lysine acetylation in human spermatozoa (sperm).
Topics: Acetylation; Amino Acid Motifs; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibody Specificity; Catechin; Consensus Sequence; Cyclosporine; Humans; Lysine; Male; Membrane Potential, Mitochondrial; Mice; Molecular Sequence Data; Peptide Library; Peptides; Protein Interaction Maps; Proteomics; Software; Sperm Motility; Spermatozoa; Voltage-Dependent Anion Channel 2 | 2015 |
(-)-Epigallocatechin-3-gallate reverses the expression of various tumor-suppressor genes by inhibiting DNA methyltransferases and histone deacetylases in human cervical cancer cells.
Topics: Anticarcinogenic Agents; Catechin; Chromatin Assembly and Disassembly; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Enzyme Induction; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; HeLa Cells; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Models, Molecular; Molecular Docking Simulation; Neoplasm Proteins; Protein Conformation; RNA, Messenger; RNA, Neoplasm; Tumor Suppressor Proteins; Uterine Cervical Neoplasms | 2015 |
Chemopreventive potential of the tannase-mediated biotransformation of green tea.
Topics: Antioxidants; Biotransformation; Camellia sinensis; Carboxylic Ester Hydrolases; Catechin; Chemoprevention; Comet Assay; Humans; Neoplasms; Plant Extracts | 2012 |
Stem cell intervention ameliorates epigallocatechin-3-gallate/lipopolysaccharide-induced hepatotoxicity in mice.
Topics: Alanine Transaminase; Alkaline Phosphatase; Amylases; Animals; Aspartate Aminotransferases; Catechin; Chemical and Drug Induced Liver Injury; Chemokine CXCL16; Chemokine CXCL6; Embryonic Stem Cells; Lipopolysaccharides; Lipoproteins, LDL; Liver; Male; Mice; Oxidative Stress; Stem Cell Transplantation; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2015 |
Epigallocatechin-3-gallate pretreatment attenuates doxorubicin-induced cardiotoxicity in rats: A mechanistic study.
Topics: Animals; Antibiotics, Antineoplastic; Base Sequence; Catechin; DNA Primers; Dose-Response Relationship, Drug; Doxorubicin; Electrocardiography; Heart; Male; Oxidative Stress; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction | 2015 |
pecific nutrient combination effects on tax, NF- κB and MMP-9 in human T-cell lymphotropic virus -1 positive malignant T-lymphocytes.
Topics: Anticarcinogenic Agents; Carcinogenesis; Catechin; CD4-Positive T-Lymphocytes; Cell Line; Cell Nucleus; Cell Proliferation; Gene Expression Regulation, Viral; Gene Products, tax; HTLV-I Infections; Human T-lymphotropic virus 1; Humans; Leukemia-Lymphoma, Adult T-Cell; Matrix Metalloproteinase 9; NF-kappa B; Protein Transport; Signal Transduction | 2015 |
Endothelial NO Production Is Mandatory for Epigallocatechin-3-Gallate-induced Vasodilation: Results From eNOS Knockout (eNOS-/-) Mice.
Topics: Animals; Aorta; Catechin; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice, Knockout; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Signal Transduction; Vasodilation; Vasodilator Agents | 2015 |
Epigallocatechin-3-gallate protects against cisplatin-induced nephrotoxicity by inhibiting endoplasmic reticulum stress-induced apoptosis.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Apoptosis; Caspase 12; Catechin; Cisplatin; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Extracellular Signal-Regulated MAP Kinases; Heat-Shock Proteins; Kidney; Male; Mice; Mice, Inbred C57BL; Phosphorylation | 2015 |
Upregulation of B-cell translocation gene 2 by epigallocatechin-3-gallate via p38 and ERK signaling blocks cell proliferation in human oral squamous cell carcinoma cells.
Topics: Animals; Carcinoma, Squamous Cell; Catechin; Cell Growth Processes; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; G1 Phase Cell Cycle Checkpoints; Gene Knockdown Techniques; Head and Neck Neoplasms; Humans; Immediate-Early Proteins; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mice, Nude; Mouth Neoplasms; p38 Mitogen-Activated Protein Kinases; Squamous Cell Carcinoma of Head and Neck; Tumor Suppressor Proteins; Up-Regulation; Xenograft Model Antitumor Assays | 2015 |
Effects of phytochemicals on in vitro anti-inflammatory activity of Bifidobacterium adolescentis.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Bifidobacterium; Catechin; Cell Line; Coculture Techniques; Dose-Response Relationship, Drug; Flavonoids; Glucosides; Lactic Acid; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Phytochemicals; Probiotics; Quercetin | 2015 |
Enhanced in vitro and in vivo cellular imaging with green tea coated water-soluble iron oxide nanocrystals.
Topics: Animals; Camellia sinensis; Catechin; Cell Line; Cell Survival; Ferric Compounds; Humans; Macrophages; Magnetic Resonance Imaging; Mice; Nanoparticles; Plant Extracts | 2015 |
Epigallocatechin gallate (EGCG) suppresses lipopolysaccharide-induced Toll-like receptor 4 (TLR4) activity via 67 kDa laminin receptor (67LR) in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Inflammatory Agents; Catechin; Interleukin-6; Lipopolysaccharides; Mice; NF-kappa B; Receptors, Laminin; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2015 |
(-)-Epigallocatechin-3-gallate inhibits osteosarcoma cell invasiveness by inhibiting the MEK/ERK signaling pathway in human osteosarcoma cells.
Topics: Bone Neoplasms; Catechin; Cell Adhesion; Cell Line, Tumor; Cell Movement; Extracellular Signal-Regulated MAP Kinases; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Neoplasm Invasiveness; Osteosarcoma | 2015 |
Bioactivity-guided fractionation of an antidiarrheal Chinese herb Rhodiola kirilowii (Regel) Maxim reveals (-)-epicatechin-3-gallate and (-)-epigallocatechin-3-gallate as inhibitors of cystic fibrosis transmembrane conductance regulator.
Topics: Animals; Antidiarrheals; Catechin; Cell Line; Cystic Fibrosis Transmembrane Conductance Regulator; Drugs, Chinese Herbal; Humans; Mice; Rats; Rats, Wistar; Rhodiola | 2015 |
Cloning and characterization of a novel O-methyltransferase from Flammulina velutipes that catalyzes methylation of pyrocatechol and pyrogallol structures in polyphenols.
Topics: Amino Acid Sequence; Catechin; Catechol O-Methyltransferase; Catechols; Cloning, Molecular; Escherichia coli; Flammulina; Fungal Proteins; Gallic Acid; Methylation; Methyltransferases; Molecular Sequence Data; Molecular Structure; Polyphenols; Pyrogallol; Recombinant Proteins; Substrate Specificity | 2015 |
Effect of epigallocatechin gallate on uncoupling protein 2 in acute liver injury.
Topics: Animals; Antioxidants; Catechin; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Ion Channels; Male; Mitochondrial Proteins; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Thioacetamide; Uncoupling Protein 2 | 2015 |
Structure-dependent inhibitory effects of green tea catechins on insulin secretion from pancreatic β-cells.
Topics: Calcium; Calcium Channels; Catechin; Glucose; Insulin; Insulin Secretion; Insulin-Secreting Cells; Structure-Activity Relationship; Tea | 2015 |
Epigallocatechin-3-gallate attenuates transforming growth factor-β1 induced epithelial-mesenchymal transition via Nrf2 regulation in renal tubular epithelial cells.
Topics: Animals; Catechin; Cell Line; Epithelial Cells; Epithelial-Mesenchymal Transition; Kidney Tubules, Proximal; NF-E2-Related Factor 2; Rats; Transforming Growth Factor beta1 | 2015 |
Study of the relationship between taste sensor response and the amount of epigallocatechin gallate adsorbed onto a lipid-polymer membrane.
Topics: Adsorption; Biosensing Techniques; Catechin; Humans; Lipids; Membranes, Artificial; Polymers; Taste | 2015 |
Green tea polyphenol (-)-epigallocatechin-3-gallate restores Nrf2 activity and ameliorates crescentic glomerulonephritis.
Topics: Animals; Antioxidants; Catechin; Glomerulonephritis; Kidney; Male; Mice; Mice, 129 Strain; Mitogen-Activated Protein Kinases; NF-E2-Related Factor 2; Oxidative Stress; PPAR gamma; Signal Transduction; Sirtuin 1; Tea | 2015 |
Epigallocatechin-3-O-Gallate Protects Against Hepatic Damage and Testicular Toxicity in Male Mice Exposed to Di-(2-Ethylhexyl) Phthalate.
Topics: Animals; Apoptosis; Aromatase; Catechin; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Esters; Injections, Intraperitoneal; Liver; Male; Mice; Organ Size; Phthalic Acids; Reproduction; RNA, Messenger; Spermatozoa; Testicular Diseases; Testis; Testosterone | 2015 |
Green tea polyphenol epigallocatechin-3-gallate and cranberry proanthocyanidins act in synergy with cathelicidin (LL-37) to reduce the LPS-induced inflammatory response in a three-dimensional co-culture model of gingival epithelial cells and fibroblasts.
Topics: Aggregatibacter actinomycetemcomitans; Antimicrobial Cationic Peptides; Catechin; Cathelicidins; Coculture Techniques; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Fibroblasts; Gingiva; Humans; Inflammation Mediators; Lipopolysaccharides; Plant Extracts; Proanthocyanidins; Tea; Vaccinium macrocarpon | 2015 |
Effect of (-)-epigallocatechin-3-gallate on glucose-induced human serum albumin glycation.
Topics: Antioxidants; Catechin; Glucose; Glycosylation; Humans; Serum Albumin | 2015 |
Nrf2 activation attenuates both orthodontic tooth movement and relapse.
Topics: Animals; Antioxidants; Catechin; Cell Line; Free Radical Scavengers; Heme Oxygenase-1; Isothiocyanates; Macrophages; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Osteoclasts; Oxidative Stress; RANK Ligand; Reactive Oxygen Species; Recurrence; Signal Transduction; Stem Cells; Sulfoxides; Tooth Movement Techniques | 2015 |
Exercise but not (-)-epigallocatechin-3-gallate or β-alanine enhances physical fitness, brain plasticity, and behavioral performance in mice.
Topics: Administration, Oral; Analysis of Variance; Animals; beta-Alanine; Body Composition; Brain; Bromodeoxyuridine; Catechin; Conditioning, Psychological; Eating; Fatigue; Fear; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred BALB C; Neuroprotective Agents; Physical Conditioning, Animal; Physical Fitness; Random Allocation | 2015 |
Calcium desensitizer catechin reverses diastolic dysfunction in mice with restrictive cardiomyopathy.
Topics: Animals; Calcium; Cardiomyopathy, Restrictive; Catechin; Cell Size; Diastole; Electrocardiography; Mice, Transgenic; Myocytes, Cardiac; Sarcomeres; Troponin I | 2015 |
A derivative of epigallocatechin-3-gallate induces apoptosis via SHP-1-mediated suppression of BCR-ABL and STAT3 signalling in chronic myelogenous leukaemia.
Topics: Animals; Antineoplastic Agents; Apoptosis; Catechin; Cell Cycle; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fusion Proteins, bcr-abl; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Signal Transduction; STAT3 Transcription Factor; Structure-Activity Relationship; Tumor Cells, Cultured | 2015 |
The anti-fibrotic effects of epigallocatechin-3-gallate in bile duct-ligated cholestatic rats and human hepatic stellate LX-2 cells are mediated by the PI3K/Akt/Smad pathway.
Topics: Animals; Bile Ducts; Catechin; Cell Line; Cholestasis; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; Male; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins | 2015 |
The protective role of (-)-epigallocatechin-3-gallate in thrombin-induced neuronal cell apoptosis and JNK-MAPK activation.
Topics: Animals; Anthracenes; Apoptosis; Caspase 3; Catechin; Cell Survival; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Inhibitors; L-Lactate Dehydrogenase; MAP Kinase Kinase 4; Neurons; Neuroprotective Agents; Phosphorylation; Rats; Thrombin; Time Factors | 2015 |
Interferon-γ Decreases Nuclear Localization of Pdx-1 and Triggers β-Cell Dysfunction in Chronic Pancreatitis.
Topics: Catechin; Cell Nucleus; Demography; Female; Gene Expression Regulation; Homeodomain Proteins; Humans; Insulin; Insulin-Secreting Cells; Interferon-gamma; Interleukin-10; Male; Pancreatitis, Chronic; Protein Transport; Trans-Activators | 2015 |
Mechanisms of DNA methyltransferase-inhibitor interactions: Procyanidin B2 shows new promise for therapeutic intervention of cancer.
Topics: Amino Acid Sequence; Animals; Biflavonoids; Breast; Breast Neoplasms; Catechin; Cell Line, Tumor; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Humans; Mice; Molecular Docking Simulation; Molecular Sequence Data; Proanthocyanidins; Sequence Alignment | 2015 |
Epigallocatechin-3-gallate attenuates lipopolysaccharide-induced mastitis in rats via suppressing MAPK mediated inflammatory responses and oxidative stress.
Topics: Animals; Blotting, Western; Catechin; Disease Models, Animal; Female; Lipopolysaccharides; Male; Mammary Glands, Animal; Mastitis; Mitogen-Activated Protein Kinase Kinases; Oxidative Stress; Pregnancy; Rats, Sprague-Dawley | 2015 |
EGCG prevents tryptophan oxidation of cataractous ocular lens human γ-crystallin in presence of H2O2.
Topics: Cataract; Catechin; gamma-Crystallins; Humans; Hydrogen Peroxide; Lens, Crystalline; Middle Aged; Molecular Docking Simulation; Oxidation-Reduction; Protein Conformation; Tryptophan | 2015 |
The Bmi-1 helix-turn and ring finger domains are required for Bmi-1 antagonism of (-) epigallocatechin-3-gallate suppression of skin cancer cell survival.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Survival; Gene Expression Regulation; Humans; Mutation; Polycomb Repressive Complex 1; Polycomb-Group Proteins; RING Finger Domains; Skin Neoplasms | 2015 |
Epigallocatechin-3-gallate inhibits nicotine-induced migration and invasion by the suppression of angiogenesis and epithelial-mesenchymal transition in non-small cell lung cancer cells.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Humans; Mice; Neoplasm Invasiveness; Neoplasm Proteins; Neovascularization, Pathologic; Nicotine; Smoking; Tea; Xenograft Model Antitumor Assays | 2015 |
Epigallocatechin gallate stimulates the neuroreactive salivary secretomotor system in autoimmune sialadenitis of MRL-Fas(lpr) mice via activation of cAMP-dependent protein kinase A and inactivation of nuclear factor κB.
Topics: Animals; Aquaporin 5; Autoimmune Diseases; Catechin; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Gene Expression Regulation; Histone Deacetylase 1; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred MRL lpr; NF-kappa B; Protein Subunits; Reactive Oxygen Species; Salivary Glands; Sialadenitis; Submandibular Gland | 2015 |
Dual targeted therapy with p53 siRNA and Epigallocatechingallate in a triple negative breast cancer cell model.
Topics: Anticarcinogenic Agents; Apoptosis; Autophagy; Blotting, Western; Catechin; Cell Proliferation; Combined Modality Therapy; Female; Gene Expression Regulation, Neoplastic; Humans; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Triple Negative Breast Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2015 |
[Efficacy of epigallocatechin gallate in treatment of alkali burn injury of murine cornea].
Topics: Alkalies; Animals; Burns, Chemical; Catechin; Cornea; Corneal Neovascularization; Disease Models, Animal; Eye Burns; Inflammation; Mice; Mice, Inbred C57BL; Neutrophils; RNA, Messenger; Vascular Endothelial Growth Factor A | 2015 |
Novel epigallocatechin-3-gallate (EGCG) derivative as a new therapeutic strategy for reducing neuropathic pain after chronic constriction nerve injury in mice.
Topics: Animals; Catechin; Cell Membrane; Cytokines; Fatty Acid Synthase, Type I; Fatty Acids; Gene Expression Regulation; Hyperalgesia; Male; Mice; Neuralgia; Pain; Pain Threshold; Peripheral Nerve Injuries; Spinal Cord Injuries | 2015 |
Combination of erlotinib and EGCG induces apoptosis of head and neck cancers through posttranscriptional regulation of Bim and Bcl-2.
Topics: Anticarcinogenic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Catechin; Cell Line, Tumor; Cycloheximide; Drug Synergism; Erlotinib Hydrochloride; Extracellular Signal-Regulated MAP Kinases; Head and Neck Neoplasms; Humans; Membrane Proteins; Phosphorylation; Protein Biosynthesis; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; RNA Interference | 2015 |
Impact and significance of EGCG on Smad, ERK, and β-catenin pathways in transdifferentiation of renal tubular epithelial cells.
Topics: Animals; beta Catenin; Catechin; Cell Line; Epithelial Cells; Epithelial-Mesenchymal Transition; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Kidney Tubules; Protective Agents; Rats; Signal Transduction; Smad3 Protein | 2015 |
Epigallocatechin-3-gallate and zinc provide anti-apoptotic protection against hypoxia/reoxygenation injury in H9c2 rat cardiac myoblast cells.
Topics: Animals; Apoptosis; Catechin; Cell Hypoxia; Cell Line; Cell Survival; Hypoxia; Male; Myoblasts, Cardiac; Oxygen; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Zinc | 2015 |
Epigallocatechin-3-gallate protects HUVECs from PM2.5-induced oxidative stress injury by activating critical antioxidant pathways.
Topics: Antioxidants; Catechin; Cell Survival; Gene Expression Regulation; Gene Silencing; Heme Oxygenase-1; Human Umbilical Vein Endothelial Cells; Humans; Inhibitory Concentration 50; MAP Kinase Signaling System; Molecular Structure; NF-E2-Related Factor 2; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Particulate Matter; Reactive Oxygen Species; Signal Transduction | 2015 |
Attenuation of progressive hearing loss in DBA/2J mice by reagents that affect epigenetic modifications is associated with up-regulation of the zinc importer Zip4.
Topics: Animals; Catechin; Cation Transport Proteins; Cochlea; Down-Regulation; Epigenesis, Genetic; Evoked Potentials, Auditory, Brain Stem; Hearing Loss; Immunohistochemistry; Methionine; Mice; Mice, Inbred DBA; Microscopy, Fluorescence; Oligonucleotide Array Sequence Analysis; Organ of Corti; Real-Time Polymerase Chain Reaction; Spiral Ganglion; Up-Regulation; Valproic Acid | 2015 |
Mitochondrial modulation by Epigallocatechin 3-Gallate ameliorates cisplatin induced renal injury through decreasing oxidative/nitrative stress, inflammation and NF-kB in mice.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Catechin; Cell Line; Cisplatin; Humans; Inflammation; Kidney; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Oxidative Stress; Renal Insufficiency | 2015 |
Green tea extract and its major constituent epigallocatechin-3-gallate inhibit growth and halitosis-related properties of Solobacterium moorei.
Topics: Anti-Bacterial Agents; Antioxidants; Bacterial Adhesion; beta-Galactosidase; Biofilms; Camellia sinensis; Catechin; Enzyme Inhibitors; Gram-Positive Bacteria; Halitosis; Humans; Plant Extracts; Polyphenols; Tea | 2015 |
(-)-Epigallocatechin-3-gallate attenuates cognitive deterioration in Alzheimer's disease model mice by upregulating neprilysin expression.
Topics: Alzheimer Disease; Animals; Catechin; Cell Proliferation; Cells, Cultured; CHO Cells; Cognition Disorders; Cricetulus; Disease Models, Animal; Mice; Neprilysin; Stereoisomerism; Up-Regulation | 2015 |
Sequential release of epigallocatechin gallate and paclitaxel from PLGA-casein core/shell nanoparticles sensitizes drug-resistant breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Caseins; Catechin; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Lactic Acid; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2015 |
Supplements for weight loss: hype or help for obesity? Part III.
Topics: Amorphophallus; Catechin; Dietary Fiber; Dietary Supplements; Fish Oils; Galactans; Garcinia cambogia; Humans; Mannans; Meta-Analysis as Topic; Obesity; Panax; Plant Gums; Plant Roots; Psyllium; Tea; Trigonella; Weight Loss | 2015 |
Green tea polyphenol epigallocatechin-3-gallate ameliorates insulin resistance in non-alcoholic fatty liver disease mice.
Topics: Animals; Biomarkers; Blood Glucose; Camellia sinensis; Catechin; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulysin; Liver; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Phytotherapy; Plants, Medicinal; Time Factors | 2015 |
Rosiglitazone, but not epigallocatechin-3-gallate, attenuates the decrease in PGC-1α protein levels in palmitate-induced insulin-resistant C2C12 cells.
Topics: Animals; Antioxidants; Catechin; Cell Line; Creatine Kinase; Glucose; Hypoglycemic Agents; Insulin Resistance; Mice; Muscle Fibers, Skeletal; Myoblasts; Palmitates; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rosiglitazone; Thiazolidinediones; Transcription Factors | 2015 |
Green Tea Polyphenols Protects Cochlear Hair Cells from Ototoxicity by Inhibiting Notch Signalling.
Topics: Amyloid Precursor Protein Secretases; Animals; Catechin; Cell Proliferation; Cochlea; Down-Regulation; Electrophysiological Phenomena; Gentamicins; Hair Cells, Auditory; Humans; In Vitro Techniques; Mechanotransduction, Cellular; Mice; Mice, Transgenic; Polyphenols; Protein Synthesis Inhibitors; Receptors, Notch; Regeneration; Signal Transduction; Tea | 2015 |
Catechin inhibition of influenza neuraminidase and its molecular basis with mass spectrometry.
Topics: Animals; Antiviral Agents; Binding Sites; Catechin; Cell Line; Dogs; Enzyme Inhibitors; Influenza A Virus, H1N1 Subtype; Madin Darby Canine Kidney Cells; N-Acetylneuraminic Acid; Neuraminidase; Orthomyxoviridae Infections; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tea | 2015 |
Epigallocatechin-3-gallate reduces tubular cell apoptosis in mice with ureteral obstruction.
Topics: Animals; Apoptosis; Biomarkers; Blotting, Western; Catechin; Cell Line; Flow Cytometry; In Situ Nick-End Labeling; Kidney Tubules; MAP Kinase Signaling System; Mice; Protective Agents; Rats; Ureteral Obstruction | 2015 |
Epigallocatechin-3-gallate treatment reduces thermal hyperalgesia after spinal cord injury by down-regulating RhoA expression in mice.
Topics: Animals; Catechin; Contusions; Down-Regulation; Female; Hyperalgesia; Locomotion; Mice; Mice, Inbred BALB C; Nerve Fibers; Nociceptors; Pain Measurement; Recovery of Function; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Spinal Cord; Spinal Cord Injuries; Tumor Necrosis Factor-alpha | 2016 |
Effect of polyphenolic phytochemicals on ectopic oxidative phosphorylation in rod outer segments of bovine retina.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Benzodioxoles; Caspase 3; Caspase 9; Catechin; Cattle; Curcumin; Cytochromes c; Hydrogen Peroxide; Malondialdehyde; Oxidative Phosphorylation; Oxygen Consumption; Phytochemicals; Piperidines; Polyunsaturated Alkamides; Quercetin; Resveratrol; Rod Cell Outer Segment; Stilbenes | 2015 |
In vitro toxicity of epigallocatechin gallate in rat liver mitochondria and hepatocytes.
Topics: Animals; Caspase 3; Catechin; Cell Survival; Cells, Cultured; Hepatocytes; Male; Membrane Potential, Mitochondrial; Microscopy, Fluorescence; Mitochondria, Liver; Oxidative Phosphorylation; Rats; Rats, Wistar; Reactive Oxygen Species; Tea; Tumor Necrosis Factor-alpha | 2015 |
Epigallocatechin-3-gallate enhances the therapeutic effects of leptomycin B on human lung cancer a549 cells.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Cytochrome P-450 CYP3A; Down-Regulation; Fatty Acids, Unsaturated; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Reactive Oxygen Species; Superoxide Dismutase; Survivin; Up-Regulation | 2015 |
Epigallocatechin-3-gallate inhibits VCAM-1 expression and apoptosis induction associated with LC3 expressions in TNFα-stimulated human endothelial cells.
Topics: Apoptosis; Caspases; Catechin; Cell Adhesion; Cell Line; Chemokine CCL2; Endothelial Cells; Glutamates; Humans; Intercellular Adhesion Molecule-1; Microtubule-Associated Proteins; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2015 |
EGCG Enhances Cisplatin Sensitivity by Regulating Expression of the Copper and Cisplatin Influx Transporter CTR1 in Ovary Cancer.
Topics: Animals; Catechin; Cation Transport Proteins; Cell Line, Tumor; Cisplatin; Copper Transporter 1; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Ovarian Neoplasms; Xenograft Model Antitumor Assays | 2015 |
Quinopeptide formation associated with the disruptive effect of epigallocatechin-gallate on lysozyme fibrils.
Topics: Amyloid; Animals; Catechin; Molecular Structure; Muramidase; Peptides; Polyphenols; Protein Aggregation, Pathological | 2015 |
D-Galactose High-Dose Administration Failed to Induce Accelerated Aging Changes in Neurogenesis, Anxiety, and Spatial Memory on Young Male Wistar Rats.
Topics: Aging; Animals; Anxiety; Body Weight; Catechin; Dentate Gyrus; Diet; Doublecortin Domain Proteins; Doublecortin Protein; Galactose; Ki-67 Antigen; Male; Maze Learning; Microtubule-Associated Proteins; Neurogenesis; Neurons; Neuropeptides; Rats, Wistar; Spatial Memory | 2015 |
Inhibition of the aggregation of lactoferrin and (-)-epigallocatechin gallate in the presence of polyphenols, oligosaccharides, and collagen peptide.
Topics: Catechin; Collagen; Food Additives; Humans; Lactoferrin; Oligosaccharides; Polyphenols; Protein Aggregates; Protein Structure, Secondary | 2015 |
Complexes of green tea polyphenol, epigalocatechin-3-gallate, and 2S albumins of peanut.
Topics: 2S Albumins, Plant; Arachis; Binding Sites; Catechin; Circular Dichroism; Protein Structure, Secondary; Tea | 2015 |
Fabrication mechanism and structural characteristics of the ternary aggregates by lactoferrin, pectin, and (-)-epigallocatechin gallate using multispectroscopic methods.
Topics: Animals; Catechin; Cattle; Circular Dichroism; Fluorescence; Lactoferrin; Particle Size; Pectins; Protein Structure, Secondary; Viscosity | 2015 |
Epigallocatechin 3-gallate ameliorates bile duct ligation induced liver injury in mice by modulation of mitochondrial oxidative stress and inflammation.
Topics: Animals; Bile Ducts, Intrahepatic; Catechin; Cell Death; Cholestasis; Cytokines; Disease Models, Animal; Gene Expression Regulation; Hepatic Stellate Cells; Hepatocytes; Inflammation; Liver Cirrhosis; Mice; Mitochondria; NF-kappa B; Oxidative Stress | 2015 |
Molecular weight and galloylation affect grape seed extract constituents' ability to cross-link dentin collagen in clinically relevant time.
Topics: Biflavonoids; Catechin; Collagen; Cross-Linking Reagents; Dentin; Grape Seed Extract; Humans; In Vitro Techniques; Mass Spectrometry; Materials Testing; Molar; Molecular Structure; Molecular Weight; Polymerization; Proanthocyanidins; Spectroscopy, Fourier Transform Infrared; Surface Properties; Tensile Strength; Time Factors | 2015 |
Green tea EGCG plus fish oil omega-3 dietary supplements rescue mitochondrial dysfunctions and are safe in a Down's syndrome child.
Topics: Catechin; Child; Dietary Supplements; Down Syndrome; Fatty Acids, Omega-3; Fish Oils; Humans; Mitochondria; Tea | 2015 |
Epigallocatechin gallate attenuated non-alcoholic steatohepatitis induced by methionine- and choline-deficient diet.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Catechin; Choline Deficiency; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Inflammation Mediators; Lipids; Liver; Male; Methionine; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Signal Transduction; Transforming Growth Factor beta | 2015 |
Epigallocatechin-3-gallate-induced free-radical production upon adipogenic differentiation in bovine bone-marrow mesenchymal stem cells.
Topics: Adipogenesis; Animals; Bone Marrow; Catechin; Cattle; Cell Differentiation; Free Radicals; Humans; Mesenchymal Stem Cells; Reactive Oxygen Species; Tea | 2015 |
High dose of epigallocatechin-3-gallate inhibits proliferation and induces apoptosis of H9C2 cardiomyocytes through down-regulation of SIRT1.
Topics: Animals; Antioxidants; Apoptosis; Catechin; Cell Line; Cell Proliferation; Cell Survival; In Situ Nick-End Labeling; Myocytes, Cardiac; Rats; Sirtuin 1 | 2015 |
Interaction mechanism between green tea extract and human α-amylase for reducing starch digestion.
Topics: Antioxidants; Catechin; Chromatography, High Pressure Liquid; Digestion; Humans; Hydrogen Bonding; Inhibitory Concentration 50; Pancreas; Pancreatic alpha-Amylases; Plant Extracts; Starch; Tea | 2015 |
Nodulisporiviridins A-H, Bioactive Viridins from Nodulisporium sp.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Androstenes; Animals; Bacteriocins; Catechin; China; Crystallography, X-Ray; Disease Models, Animal; Humans; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Xylariales | 2015 |
Potent and Nontoxic Chemosensitizer of P-Glycoprotein-Mediated Multidrug Resistance in Cancer: Synthesis and Evaluation of Methylated Epigallocatechin, Gallocatechin, and Dihydromyricetin Derivatives.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Catechin; Cell Proliferation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavonols; Humans; Methylation; Models, Molecular; Molecular Structure; Neoplasm Proteins; Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured | 2015 |
EGCG-mediated autophagy flux has a neuroprotection effect via a class III histone deacetylase in primary neuron cells.
Topics: Apoptosis; Autophagy; bcl-2-Associated X Protein; Catechin; Cell Line; Histone Deacetylases; Humans; Membrane Potential, Mitochondrial; Mitochondria; Neurons; Neuroprotection; Neuroprotective Agents; Prions; RNA; RNA, Small Interfering; Sirtuin 1 | 2015 |
[Interaction of fish collagen peptide with epigallocatechin gallate].
Topics: Animals; Antioxidants; Catechin; Collagen; Fishes; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared | 2015 |
Epigallocatechin-3-gallate opposes HBV-induced incomplete autophagy by enhancing lysosomal acidification, which is unfavorable for HBV replication.
Topics: Antiviral Agents; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; DNA Replication; DNA, Viral; Hep G2 Cells; Hepatitis B virus; Humans; Liver Neoplasms; Lysosomes; Microtubule-Associated Proteins; Plant Extracts; RNA Interference; RNA, Small Interfering; Tea; Ubiquitin-Activating Enzymes; Viral Core Proteins; Virus Replication | 2015 |
EGCG synergizes the therapeutic effect of cisplatin and oxaliplatin through autophagic pathway in human colorectal cancer cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Autophagy; Catechin; Cell Transformation, Neoplastic; Cisplatin; Colorectal Neoplasms; Drug Synergism; HT29 Cells; Humans; Microtubule-Associated Proteins; Organoplatinum Compounds; Oxaliplatin; Signal Transduction; Tea; Tumor Cells, Cultured | 2015 |
Epigallocatechin gallate attenuates fibroblast proliferation and excessive collagen production by effectively intervening TGF-β1 signalling.
Topics: Animals; Bleomycin; Catechin; Cell Differentiation; Cell Proliferation; Collagen; Fibroblasts; Gene Expression Regulation, Enzymologic; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Rats; Rats, Wistar; Signal Transduction; Transforming Growth Factor beta1 | 2015 |
[Effect of epigallocatechin gallate against exercise-induced fatigue in mice].
Topics: Animals; Blood Urea Nitrogen; Catechin; Exercise Tolerance; Fatigue; Glycogen; L-Lactate Dehydrogenase; Mice; Physical Conditioning, Animal | 2015 |
Fluphenazine·HCl and Epigallocatechin Gallate Modulate the Rate of Formation and Structural Properties of Apolipoprotein C-II Amyloid Fibrils.
Topics: Amyloid; Antipsychotic Agents; Apolipoprotein C-II; Benzothiazoles; Binding, Competitive; Catechin; Drug Discovery; Drugs, Investigational; Fluphenazine; Humans; Kinetics; Microscopy, Electron, Transmission; Neuroprotective Agents; Particle Size; Protein Aggregates; Protein Conformation; Proteostasis Deficiencies; Recombinant Proteins; Small Molecule Libraries; Thiazoles; Ultracentrifugation | 2015 |
MST-312 induces G2/M cell cycle arrest and apoptosis in APL cells through inhibition of telomerase activity and suppression of NF-κB pathway.
Topics: Apoptosis; Benzamides; Catechin; Cell Line, Tumor; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Promyelocytic, Acute; NF-kappa B; Phosphorylation; Signal Transduction; Telomerase | 2015 |
Fish β-parvalbumin acquires allergenic properties by amyloid assembly.
Topics: Amyloid; Animals; Catechin; Cross Reactions; Endopeptidase K; Fish Proteins; Fishes; Food Hypersensitivity; Humans; Immunoglobulin E; Parvalbumins; Pepsin A; Seafood | 2015 |
Preventive effects of a major component of green tea, epigallocathechin-3-gallate, on hepatitis-B virus DNA replication.
Topics: Antioxidants; Camellia sinensis; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; DNA Replication; DNA, Viral; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Liver Neoplasms; Tea; Virus Replication | 2015 |
A new method for measuring osteoclast formation by electrical impedance.
Topics: Bone Resorption; Catechin; Cell Differentiation; Cells, Cultured; Computer Systems; Cytological Techniques; Electric Impedance; Humans; Macrophage Colony-Stimulating Factor; Osteoclasts; RANK Ligand | 2015 |
Biochemical and histopathological effects of catechin on experimental peripheral nerve injuries.
Topics: Animals; Catechin; Disease Models, Animal; Male; Neuroprotective Agents; Peripheral Nerve Injuries; Rats; Rats, Wistar | 2015 |
Differences in binding behavior of (-)-epigallocatechin gallate to β-lactoglobulin heterodimers (AB) compared to homodimers (A) and (B).
Topics: Animals; Binding Sites; Catechin; Cattle; Lactoglobulins; Ligands; Milk; Protein Binding; Protein Multimerization; Protein Structure, Secondary; Scattering, Small Angle; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2015 |
EGCG regulates the cross-talk between JWA and topoisomerase IIα in non-small-cell lung cancer (NSCLC) cells.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; DNA Topoisomerases, Type II; DNA-Binding Proteins; Female; Heat-Shock Proteins; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Membrane Transport Proteins; Mice, Inbred BALB C; Mice, Nude; Proteolysis; Xenograft Model Antitumor Assays | 2015 |
Decaffeinated green tea extract rich in epigallocatechin-3-gallate improves insulin resistance and metabolic profiles in normolipidic diet--but not high-fat diet-fed mice.
Topics: Absorption, Physicochemical; Adipose Tissue, White; Adiposity; Animals; Anti-Obesity Agents; Biomarkers; Brazil; Camellia sinensis; Catechin; Diet, High-Fat; Dietary Supplements; Food Handling; Hyperlipidemias; Hypolipidemic Agents; Insulin Resistance; Male; Mice; Obesity; Plant Extracts; Plant Leaves; Random Allocation; Weight Gain | 2015 |
Neuroprotective effect of epigallocatechin-3-gallate in a mouse model of chronic glaucoma.
Topics: Administration, Oral; Animals; Catechin; Cell Survival; Chronic Disease; Female; Glaucoma; Intraocular Pressure; Mice, Inbred C57BL; Neuroprotective Agents; Retinal Ganglion Cells | 2015 |
Incubator proof miniaturized Holomonitor to in situ monitor cancer cells exposed to green tea polyphenol and preosteoblast cells adhering on nanostructured titanate surfaces: validity of the measured parameters and their corrections.
Topics: Animals; Catechin; Cell Adhesion; Cell Line; Cell Movement; HeLa Cells; Holography; Humans; Mice; Microscopy; Nanostructures; Neoplasms; Reproducibility of Results; Single-Cell Analysis; Tea; Titanium | 2015 |
Targeting increased copper levels in diethylnitrosamine induced hepatocellular carcinoma cells in rats by epigallocatechin-3-gallate.
Topics: Animals; Carcinoma, Hepatocellular; Catechin; Cell Membrane Permeability; Copper; Diethylnitrosamine; DNA Damage; Free Radical Scavengers; Humans; Liver Neoplasms; Oxidative Stress; Rats; Reactive Oxygen Species; Tea | 2015 |
Protective effects of epigallocatechin-3-gallate on intestinal ischemia reperfusion injury through enhanced activation of PI3K/Akt pathway in rats.
Topics: Animals; Anti-Inflammatory Agents; Catechin; Disease Models, Animal; Gene Expression Regulation; Interleukin-1; Interleukin-6; Intestines; Male; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction; Tumor Necrosis Factor-alpha | 2015 |
Computational and Biochemical Discovery of RSK2 as a Novel Target for Epigallocatechin Gallate (EGCG).
Topics: Adenosine Triphosphate; Animals; Binding, Competitive; Catalytic Domain; Catechin; Cell Line; Cell Survival; Computational Biology; Drug Evaluation, Preclinical; Epidermal Growth Factor; Mice; Molecular Docking Simulation; Molecular Targeted Therapy; Protein Kinase Inhibitors; Ribosomal Protein S6 Kinases, 90-kDa | 2015 |
The Effect of (-)-Epigallo-catechin-(3)-gallate on Amyloidogenic Proteins Suggests a Common Mechanism.
Topics: Amyloidogenic Proteins; Animals; Catechin; Humans; Protein Aggregates; Protein Multimerization | 2015 |
The green tea catechin epigallocatechin gallate induces cell cycle arrest and shows potential synergism with cisplatin in biliary tract cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Biliary Tract Neoplasms; Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Synergism; Humans | 2015 |
Dual fatty acid synthase and HER2 signaling blockade shows marked antitumor activity against breast cancer models resistant to anti-HER2 drugs.
Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Catechin; Cell Adhesion; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fatty Acid Synthase, Type I; Female; Gallic Acid; Humans; Lapatinib; Mice; Mice, Inbred NOD; Mice, SCID; Mutation; Naphthalenes; Neoplasm Invasiveness; Neoplasm Transplantation; Quinazolines; Receptor, ErbB-2; Signal Transduction; Sirolimus; Trastuzumab | 2015 |
Uncoupling of myofilament Ca2+ sensitivity from troponin I phosphorylation by mutations can be reversed by epigallocatechin-3-gallate.
Topics: Animals; Bepridil; Calcium; Catechin; Humans; Mice; Muscle Contraction; Mutation; Myofibrils; Phosphorylation; Quinolines; Rabbits; Thiadiazines; Troponin I | 2015 |
Local Controlled Release of Polyphenol Conjugated with Gelatin Facilitates Bone Formation.
Topics: Animals; Catechin; Cell Differentiation; Delayed-Action Preparations; Gelatin; Mesenchymal Stem Cells; Mice; Mice, Inbred ICR; Osteogenesis; Polyphenols; Skull | 2015 |
Treatment of Chronic Experimental Autoimmune Encephalomyelitis with Epigallocatechin-3-Gallate and Glatiramer Acetate Alters Expression of Heme-Oxygenase-1.
Topics: Animals; Axons; Catechin; Chronic Disease; Down-Regulation; Encephalomyelitis, Autoimmune, Experimental; Female; Gene Expression Regulation, Enzymologic; Glatiramer Acetate; Heme Oxygenase-1; Membrane Proteins; Mice; Myelin Sheath; Oxidation-Reduction | 2015 |
Do pH and flavonoids influence hypochlorous acid-induced catalase inhibition and heme modification?
Topics: Animals; Catalase; Catechin; Cattle; Heme; Hydrogen-Ion Concentration; Hypochlorous Acid; Kinetics; Liver; Quercetin | 2015 |
Correction: EGCG Enhances Cisplatin Sensitivity by Regulating Expression of the Copper and Cisplatin Influx Transporter CTR1 in Ovary Cancer.
Topics: Antineoplastic Agents; Catechin; Cation Transport Proteins; Cisplatin; Copper Transporter 1; Female; Humans; Ovarian Neoplasms | 2015 |
Protective effect of epigallocatechin gallate, a major constituent of green tea, against renal ischemia-reperfusion injury in rats.
Topics: Animals; Antioxidants; Catechin; Cytokines; Kidney; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tea; Treatment Outcome; Urokinase-Type Plasminogen Activator | 2015 |
(-)Epigallocatechin-3-gallate decreases the stress-induced impairment of learning and memory in rats.
Topics: Animals; Antioxidants; Catechin; Hippocampus; Learning Disabilities; Male; Maze Learning; Memory Disorders; Motor Activity; Rats, Sprague-Dawley; Reactive Oxygen Species; Restraint, Physical; Spatial Learning; Stress, Psychological; Thiobarbituric Acid Reactive Substances | 2015 |
Green tea polyphenol epigallocatechin-O-gallate induces cell death by acid sphingomyelinase activation in chronic myeloid leukemia cells.
Topics: Anticarcinogenic Agents; Blotting, Western; Catechin; Cell Line, Tumor; Enzyme Activation; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Membrane Microdomains; Sphingomyelin Phosphodiesterase; Tea | 2015 |
Combined Effects of Curcumin and (-)-Epigallocatechin Gallate on Inhibition of N-Acylhomoserine Lactone-Mediated Biofilm Formation in Wastewater Bacteria from Membrane Bioreactor.
Topics: Acyl-Butyrolactones; Anti-Bacterial Agents; Biofilms; Bioreactors; Catechin; Curcumin; Drug Interactions; Gram-Negative Bacteria; Microbial Sensitivity Tests; Wastewater | 2015 |
Mobilization of copper ions in human peripheral lymphocytes by catechins leading to oxidative DNA breakage: A structure activity study.
Topics: Animals; Catechin; Cations, Monovalent; Cattle; Cell Survival; Chromatin; Comet Assay; Copper; DNA; DNA Fragmentation; Humans; Lymphocytes; Molecular Docking Simulation; Oxidation-Reduction; Primary Cell Culture; Reactive Oxygen Species; Structure-Activity Relationship; Thermodynamics | 2015 |
A-type ECG and EGCG dimers disturb the structure of 3T3-L1 cell membrane and strongly inhibit its differentiation by targeting peroxisome proliferator-activated receptor γ with miR-27 involved mechanism.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Catechin; Cell Differentiation; Dimerization; Mice; MicroRNAs; PPAR gamma | 2015 |
Dietary (-)-Epigallocatechin-3-gallate Supplementation Counteracts Aging-Associated Skeletal Muscle Insulin Resistance and Fatty Liver in Senescence-Accelerated Mouse.
Topics: Aging; Animals; Camellia sinensis; Catechin; Dietary Supplements; Fatty Liver; Female; Glucose; Glucose Transporter Type 4; Humans; Insulin Resistance; Lipid Metabolism; Liver; Male; Mice; Muscle, Skeletal; Plant Extracts; Sterol Regulatory Element Binding Protein 1 | 2015 |
Paraventricular Nucleus Infusion of Epigallocatechin-3-O-Gallate Improves Renovascular Hypertension.
Topics: Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Antioxidants; Blood Pressure; Catechin; Cytokines; Disease Models, Animal; Hypertension, Renovascular; Infusions, Parenteral; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Paraventricular Hypothalamic Nucleus; Rats, Sprague-Dawley; Superoxide Dismutase-1; Time Factors | 2016 |
Differential proteomic analysis reveals that EGCG inhibits HDGF and activates apoptosis to increase the sensitivity of non-small cells lung cancer to chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; Proteomics; Structure-Activity Relationship; Tumor Cells, Cultured | 2016 |
EGCG reverses human neutrophil elastase-induced migration in A549 cells by directly binding to HNE and by regulating α1-AT.
Topics: alpha 1-Antitrypsin; Biosensing Techniques; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Leukocyte Elastase; Phosphatidylinositol 3-Kinases; Protein Binding; Proto-Oncogene Proteins c-akt; Signal Transduction; Surface Plasmon Resonance | 2015 |
Green tea component epigallocatechin-3-gallate decreases expression of osteopontin via a decrease in mRNA half-life in cell lines of metastatic hepatocellular carcinoma.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Movement; Enzyme-Linked Immunosorbent Assay; Half-Life; Humans; Liver Neoplasms; Neoplasm Metastasis; Osteopontin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2015 |
(-)Epigallocatechin-3-gallate prevents the reserpine-induced impairment of short-term social memory in rats.
Topics: Animals; Antioxidants; Behavior, Animal; Catechin; Drug Interactions; Hippocampus; Lipid Peroxidation; Male; Maze Learning; Memory, Short-Term; Oxidative Stress; Rats; Rats, Wistar; Reserpine; Social Behavior; Social Behavior Disorders | 2015 |
Neuroprotective Effects of (-)-Epigallocatechin-3-Gallate Against Focal Cerebral Ischemia/Reperfusion Injury in Rats Through Attenuation of Inflammation.
Topics: Animals; Brain Ischemia; Catechin; Inflammation; Inflammation Mediators; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Treatment Outcome | 2015 |
Polyphenols Inhibit Hepatitis C Virus Entry by a New Mechanism of Action.
Topics: Anthocyanins; Antiviral Agents; Catechin; Cell Line; Cryoelectron Microscopy; Drug Evaluation, Preclinical; HEK293 Cells; Hepacivirus; Hepatocytes; Humans; Interferon-alpha; Polyphenols; Proline; Virus Internalization | 2015 |
Rescue of the abnormal skeletal phenotype in Ts65Dn Down syndrome mice using genetic and therapeutic modulation of trisomic Dyrk1a.
Topics: Animals; Bone Diseases; Catechin; Disease Models, Animal; Down Syndrome; Dyrk Kinases; Gene Dosage; Male; Mice; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases | 2015 |
Epigallocatechin-3-gallate enhances clearance of phosphorylated tau in primary neurons.
Topics: Animals; Antioxidants; Autophagy; Catechin; Cell Line, Tumor; Humans; Microtubules; Neurons; NF-E2-Related Factor 2; Nuclear Proteins; Phosphorylation; Phytochemicals; Rats; Rats, Sprague-Dawley; RNA-Binding Proteins; RNA, Messenger; tau Proteins; Tea | 2016 |
Antiglycation activity of lipophilized epigallocatechin gallate (EGCG) derivatives.
Topics: Antioxidants; Catechin; Freeze Drying; Glycation End Products, Advanced; Pyruvaldehyde; Structure-Activity Relationship | 2016 |
Inhibition of Light Chain 6aJL2-R24G Amyloid Fiber Formation Associated with Light Chain Amyloidosis.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amyloid; Amyloidosis; Catechin; Humans; Immunoglobulin Light Chains; In Vitro Techniques; Melatonin; Microscopy, Electron, Transmission; Models, Molecular; Molecular Sequence Data; Mutation, Missense; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Multimerization; Quercetin; Recombinant Proteins; Rifampin; Tetracycline | 2015 |
Heat treatment enhances the antimicrobial activity of (+)-Catechin when combined with copper sulphate.
Topics: Anti-Bacterial Agents; Catechin; Copper Sulfate; Hot Temperature; Hydrogen Peroxide; Microbial Sensitivity Tests; Staphylococcus aureus; Structure-Activity Relationship | 2015 |
Tumor-Homing Cell-Penetrating Peptide Linked to Colloidal Mesoporous Silica Encapsulated (-)-Epigallocatechin-3-gallate as Drug Delivery System for Breast Cancer Therapy in Vivo.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Catechin; Cell Survival; Cell-Penetrating Peptides; Drug Carriers; Female; Fluorescent Dyes; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Confocal; Nanoparticles; Particle Size; Porosity; Reactive Oxygen Species; Silicon Dioxide; Transplantation, Heterologous | 2015 |
Extraction Kinetics of phytochemicals and antioxidant activity during black tea (Camellia sinensis L.) brewing.
Topics: Antioxidants; Caffeine; Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Food Analysis; Gallic Acid; Phytochemicals; Plant Leaves; Polyphenols; Sri Lanka; Tea; Time Factors | 2015 |
A genome-wide study of DNA methylation modified by epigallocatechin-3-gallate in the CAL-27 cell line.
Topics: Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Cell Proliferation; Computational Biology; DNA Methylation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genome-Wide Association Study; Humans; Mouth Neoplasms; Signal Transduction | 2015 |
Epigallocatechin gallate hinders human hepatoma and colon cancer sphere formation.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Catechin; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Dose-Response Relationship, Drug; HCT116 Cells; Hep G2 Cells; Humans; Liver Neoplasms; Neoplastic Stem Cells; Tea | 2016 |
Synergistic effects of tea catechin epigallocatechin gallate and antimycotics against oral Candida species.
Topics: Amphotericin B; Anilides; Antifungal Agents; Biofilms; Candida; Catechin; Drug Synergism; Fluconazole; Miconazole; Microbial Sensitivity Tests; Polyphenols; Tetrazolium Salts | 2015 |
Sphingosine Kinase-1 Protects Multiple Myeloma from Apoptosis Driven by Cancer-Specific Inhibition of RTKs.
Topics: Animals; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Death-Associated Protein Kinases; Drug Synergism; Enzyme Activation; Female; Humans; Membrane Microdomains; Mice, Inbred BALB C; Multiple Myeloma; Phosphotransferases (Alcohol Group Acceptor); Receptor Protein-Tyrosine Kinases; Signal Transduction; Sphingomyelin Phosphodiesterase; Sphingosine; Xenograft Model Antitumor Assays | 2015 |
In Vitro Activity of Epigallocatechin Gallate and Quercetin Alone and in Combination versus Clinical Isolates of Methicillin-Resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Catechin; Humans; Methicillin; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Quercetin; Staphylococcus aureus; Time Factors | 2015 |
High doses of (-)-epigallocatechin-3-gallate from green tea induces cardiac fibrosis in mice.
Topics: Administration, Oral; Animals; Catechin; Collagen; Connective Tissue Growth Factor; Fibronectins; Fibrosis; Mice; Myocardium; Tea | 2015 |
Antifolate Activity of Plant Polyphenols against Mycobacterium tuberculosis.
Topics: Catechin; Folic Acid Antagonists; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Phytochemicals; Polyphenols | 2015 |
Epigallocatechin-3-gallate Increases RXRγ-mediated Pro-apoptotic and Anti-invasive Effects in Gastrointestinal Cancer Cell Lines.
Topics: Apoptosis; Catechin; Cell Line, Tumor; Drug Synergism; Forkhead Box Protein O3; Gastrointestinal Neoplasms; Humans; Ligands; Metalloproteases; Mitochondria; Phenanthrenes; Retinoid X Receptor gamma; Tea; Tretinoin | 2016 |
[Study on inhibitory effect of EGCG on Calcium oxalate nephrolithiasis in rats and its related mechanism].
Topics: Animals; Blood Urea Nitrogen; Calcium; Calcium Oxalate; Catechin; Creatinine; Disease Models, Animal; Humans; Kidney; Male; Nephrolithiasis; Osteopontin; Rats; Rats, Wistar | 2015 |
Active Targeted Nanoparticles for Oral Administration of Gastric Cancer Therapy.
Topics: Administration, Oral; Animals; Apoptosis; Catechin; Chitosan; Drug Carriers; Gelatin; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms, Experimental; Polyethylene Glycols; Stomach Neoplasms | 2015 |
Effect of Brewing Duration on the Antioxidant and Hepatoprotective Abilities of Tea Phenolic and Alkaloid Compounds in a t-BHP Oxidative Stress-Induced Rat Hepatocyte Model.
Topics: Alkaloids; Animals; Antioxidants; Caffeine; Catechin; Cell Survival; Chromatography, High Pressure Liquid; Hepatocytes; Liver; Male; Mitochondria; Models, Biological; Oxidative Stress; Phenols; Plant Extracts; Protective Agents; Rats; Spectrometry, Mass, Electrospray Ionization; Superoxides; Tea; tert-Butylhydroperoxide; Time Factors | 2015 |
EGCG induces G-CSF expression and neutrophilia in experimental sepsis.
Topics: Animals; Anti-Inflammatory Agents; Catechin; Cells, Cultured; Chemokines; Disease Models, Animal; Granulocyte Colony-Stimulating Factor; HMGB1 Protein; Humans; Leukocytes, Mononuclear; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Neutrophils; Sepsis; Tea | 2015 |
Epigallocatechin-3-O-Gallate-Loaded Poly(lactic-co-glycolic acid) Fibrous Sheets as Anti-Adhesion Barriers.
Topics: Adsorption; Animals; Antioxidants; Bandages; Catechin; Lactic Acid; Male; Materials Testing; Nanocapsules; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Surface Properties; Tissue Adhesions; Treatment Outcome | 2015 |
Screening of multi-targeted natural compounds for receptor tyrosine kinases inhibitors and biological evaluation on cancer cell lines, in silico and in vitro.
Topics: Antineoplastic Agents; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Discovery; Humans; Molecular Docking Simulation; Plant Extracts; Receptor Protein-Tyrosine Kinases; Research Design | 2015 |
Epigallocatechin‑3‑gallate inhibits the invasion of salivary adenoid cystic carcinoma cells by reversing the hypermethylation status of the RECK gene.
Topics: Carcinoma, Adenoid Cystic; Catechin; Cell Line, Tumor; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; GPI-Linked Proteins; Humans; Promoter Regions, Genetic; Tea | 2015 |
Decaffeinated green tea extract rich in epigallocatechin-3-gallate prevents fatty liver disease by increased activities of mitochondrial respiratory chain complexes in diet-induced obesity mice.
Topics: Animals; Body Weight; Catechin; Cytokines; Diet, High-Fat; Dietary Supplements; Enzymes; Glucose Tolerance Test; Insulin Resistance; Liver; Male; Mice; Non-alcoholic Fatty Liver Disease; Obesity; Tea | 2015 |
Implication of Akt, ERK1/2 and alternative p38MAPK signalling pathways in human colon cancer cell apoptosis induced by green tea EGCG.
Topics: Anticarcinogenic Agents; Antioxidants; Apoptosis; Catechin; Cell Line, Tumor; Colonic Neoplasms; Food Handling; HEK293 Cells; Humans; Isoenzymes; MAP Kinase Signaling System; Osmolar Concentration; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; RNA Interference; RNA, Small Interfering; Tea | 2015 |
Improving the sweet aftertaste of green tea infusion with tannase.
Topics: Carboxylic Ester Hydrolases; Catechin; Hydrolysis; Plant Extracts; Taste; Tea | 2016 |
Gold-conjugated green tea nanoparticles for enhanced anti-tumor activities and hepatoprotection--synthesis, characterization and in vitro evaluation.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Catechin; Drug Evaluation, Preclinical; Gold; Hepatocytes; Humans; Liver; Male; MCF-7 Cells; Mice; Nanoparticles; Tea | 2015 |
Toxicity inhibitors protect lipid membranes from disruption by Aβ42.
Topics: Amyloid beta-Peptides; Bridged-Ring Compounds; Catechin; Cryoelectron Microscopy; Dimyristoylphosphatidylcholine; Fluorescence Resonance Energy Transfer; Kinetics; Lipid Bilayers; Microscopy, Confocal; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Neuroprotective Agents; Organophosphates; Peptide Fragments; Phosphatidylglycerols; Protein Multimerization; Protein Structure, Secondary; Unilamellar Liposomes | 2015 |
Epigallocatechin Gallate/Layered Double Hydroxide Nanohybrids: Preparation, Characterization, and In Vitro Anti-Tumor Study.
Topics: Antineoplastic Agents; Catechin; Cell Line, Tumor; Humans; Hydrogen-Ion Concentration; Hydroxides; Male; Nanocomposites; Prostatic Neoplasms | 2015 |
Separation and purification of epigallocatechin-3-gallate (EGCG) from green tea using combined macroporous resin and polyamide column chromatography.
Topics: Adsorption; Catechin; Chromatography, High Pressure Liquid; Kinetics; Nylons; Tea; Thermodynamics | 2015 |
Effects of Metabolites Produced from (-)-Epigallocatechin Gallate by Rat Intestinal Bacteria on Angiotensin I-Converting Enzyme Activity and Blood Pressure in Spontaneously Hypertensive Rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Bacteria; Blood Pressure; Catechin; Hypertension; Intestines; Lactones; Male; Rats; Rats, Inbred SHR; Tea; Valerates | 2015 |
Folate deficiency-triggered redox pathways confer drug resistance in hepatocellular carcinoma.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Survival; Culture Media; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Endoplasmic Reticulum Chaperone BiP; Folic Acid; Heat-Shock Proteins; Hep G2 Cells; Humans; Inhibitor of Apoptosis Proteins; Liver Neoplasms; Oxidation-Reduction; Reactive Oxygen Species; RNA Interference; Signal Transduction; Survivin | 2015 |
Interfacial dilational properties of tea polyphenols and milk proteins with gut epithelia and the role of mucus in nutrient adsorption.
Topics: Caco-2 Cells; Catechin; Cell Survival; Coculture Techniques; HT29 Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Milk Proteins; Mucins; Mucus; Polyphenols; Rheology; Tea | 2015 |
Elevated transglutaminase-2 expression mediates fibrosis in areca quid chewing-associated oral submucocal fibrosis via reactive oxygen species generation.
Topics: Acetylcysteine; Areca; Arecoline; Blotting, Western; Catechin; Dose-Response Relationship, Drug; GTP-Binding Proteins; Humans; Immunohistochemistry; Oral Submucous Fibrosis; Protein Glutamine gamma Glutamyltransferase 2; Reactive Oxygen Species; Transglutaminases | 2016 |
Green tea component EGCG, insulin and IGF-1 promote nuclear efflux of atrophy-associated transcription factor Foxo1 in skeletal muscle fibers.
Topics: Active Transport, Cell Nucleus; Adenoviridae; Animals; Camellia; Catechin; Cell Nucleus; Cytoplasm; Dose-Response Relationship, Drug; Female; Flavonoids; Forkhead Box Protein O1; Green Fluorescent Proteins; Insulin; Insulin-Like Growth Factor I; Mice; Models, Theoretical; Muscle Fibers, Skeletal; Polyphenols; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Receptor, Insulin; Signal Transduction; Tea | 2015 |
Epigallocatechin-3-gallate (EGCG) Suppresses the Trafficking of Lymphocytes to Epidermal Melanocytes via Inhibition of JAK2: Its Implication for Vitiligo Treatment.
Topics: Anti-Inflammatory Agents; Antioxidants; Camellia sinensis; Catechin; CD11a Antigen; Cell Movement; Epidermal Cells; Epidermis; Humans; Intercellular Adhesion Molecule-1; Interferon-gamma; Janus Kinase 2; Melanocytes; Phosphorylation; Phytotherapy; Plant Extracts; Receptors, CCR2; Signal Transduction; STAT3 Transcription Factor; T-Lymphocytes; Vitiligo | 2015 |
Nanoparticle-Assisted Combinatorial Therapy for Effective Treatment of Endometriosis.
Topics: Animals; Antioxidants; Catechin; Cells, Cultured; Doxycycline; Drug Delivery Systems; Drug Evaluation, Preclinical; Drug Therapy, Combination; Endometriosis; Female; Humans; Mice; Nanoparticles; Spectroscopy, Fourier Transform Infrared; Treatment Outcome | 2015 |
Insight into the mechanism of polyphenols on the activity of HMGR by molecular docking.
Topics: Binding Sites; Catalytic Domain; Catechin; Cholesterol; Curcumin; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Molecular Docking Simulation; NADP; Polyphenols; Protein Binding; Protein Conformation; Structure-Activity Relationship | 2015 |
Green tea epigallocatechin-3-gallate alleviates Porphyromonas gingivalis-induced periodontitis in mice.
Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Cytokines; Female; Gingiva; Inflammation Mediators; Mice; Mice, Inbred BALB C; Periodontitis; Porphyromonas gingivalis; Tea | 2015 |
Effects of EGCG content in green tea extract on pharmacokinetics, oxidative status and expression of inflammatory and apoptotic genes in the rat ocular tissues.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Catechin; Dose-Response Relationship, Drug; Endophthalmitis; Eye; Female; Gene Expression Regulation; Oxidative Stress; Plant Extracts; Rats, Sprague-Dawley; Tea; Vitreous Body | 2015 |
Low dose EGCG treatment beginning in adolescence does not improve cognitive impairment in a Down syndrome mouse model.
Topics: Aging; Animals; Behavior, Animal; Brain Chemistry; Catechin; Cognition Disorders; Down Syndrome; Dyrk Kinases; Female; Growth; Learning; Maze Learning; Mice; Mice, Transgenic; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recognition, Psychology | 2015 |
Epigallocatechin-3-gallate attenuates bone cancer pain involving decreasing spinal Tumor Necrosis Factor-α expression in a mouse model.
Topics: Animals; Behavior, Animal; Bone Neoplasms; Catechin; Disease Progression; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Osteosarcoma; Pain Measurement; Pain, Intractable; Spinal Cord; Spine; Tumor Necrosis Factor-alpha | 2015 |
Epigallocatechin gallate affects glucose metabolism and increases fitness and lifespan in Drosophila melanogaster.
Topics: alpha-Amylases; alpha-Glucosidases; Animals; Antioxidants; Camellia sinensis; Catechin; Drosophila melanogaster; Drosophila Proteins; Energy Metabolism; Glucose; Homeostasis; Insulin; Longevity; Molecular Docking Simulation; Phosphoenolpyruvate Carboxykinase (ATP); Plant Extracts; Positive Transcriptional Elongation Factor B; Proteins; Transcription Factors; Up-Regulation | 2015 |
The Green Tea Component (-)-Epigallocatechin-3-Gallate Sensitizes Primary Endothelial Cells to Arsenite-Induced Apoptosis by Decreasing c-Jun N-Terminal Kinase-Mediated Catalase Activity.
Topics: Animals; Antioxidants; Aorta; Arsenites; Blotting, Western; Catalase; Catechin; Cattle; Cells, Cultured; Drug Resistance; Drug Synergism; Endothelium, Vascular; Humans; Immunoenzyme Techniques; JNK Mitogen-Activated Protein Kinases; Mitochondria; Oxidation-Reduction; Phosphorylation; Reactive Oxygen Species; Signal Transduction; Tea; Teratogens | 2015 |
Using Defatted Rice Bran as a Bioadsorbent for Carrying Tea Catechins.
Topics: Adsorption; Caffeine; Camellia sinensis; Catechin; Cellulose; Dietary Fiber; Edible Grain; Food Additives; Humans; Oryza; Plant Extracts; Plant Proteins; Tea; Temperature | 2015 |
Tea polyphenols epigallocatechin gallete and theaflavin restrict mouse liver carcinogenesis through modulation of self-renewal Wnt and hedgehog pathways.
Topics: alpha-Fetoproteins; Animals; Biflavonoids; Catechin; Female; Hedgehog Proteins; Hyaluronan Receptors; Liver; Liver Neoplasms, Experimental; Mice; Tea; Wnt Proteins | 2016 |
Prevention of hepatitis C virus infection using a broad cross-neutralizing monoclonal antibody (AR4A) and epigallocatechin gallate.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Neutralizing; Antiviral Agents; Broadly Neutralizing Antibodies; Catechin; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Genotype; Hepatitis C; Hepatitis Viruses; Humans; Liver; Mice, SCID; Time Factors | 2016 |
Exovascular application of epigallocatechin-3-O-gallate-releasing electrospun poly(L-lactide glycolic acid) fiber sheets to reduce intimal hyperplasia in injured abdominal aorta.
Topics: Animals; Antioxidants; Aorta, Abdominal; Catechin; Diffusion; Drug Implants; Electroplating; Endothelium, Vascular; Lactic Acid; Male; Membranes, Artificial; Nanocapsules; Nanopores; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Rabbits; Treatment Outcome; Vascular System Injuries | 2015 |
QIAD assay for quantitating a compound's efficacy in elimination of toxic Aβ oligomers.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Carrier Proteins; Catechin; Disease Models, Animal; Ferredoxin-NADP Reductase; Humans; Inositol; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Oligopeptides; Protein Aggregation, Pathological; Taurine | 2015 |
The Inhibition of Maillard Browning by Different Concentrations of Rosmarinic Acid and Epigallocatechin-3-Gallate in Model, Bakery, and Fruit Systems.
Topics: Antioxidants; Bread; Catechin; Cinnamates; Color; Depsides; Food Handling; Food Preservation; Fruit; Glucose; Glycine; Humans; Maillard Reaction; Malus; Reactive Oxygen Species; Rosmarinic Acid | 2015 |
Molecular docking and molecular dynamics studies reveal structural basis of inhibition and selectivity of inhibitors EGCG and OSU-03012 toward glucose regulated protein-78 (GRP78) overexpressed in glioblastoma.
Topics: Amino Acid Sequence; Catalytic Domain; Catechin; Endoplasmic Reticulum Chaperone BiP; Gene Expression; Glioblastoma; Heat-Shock Proteins; Humans; Hydrogen Bonding; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Sequence Data; Molecular Structure; Protein Binding; Protein Conformation; Protein Interaction Domains and Motifs; Pyrazoles; Quantitative Structure-Activity Relationship; Sequence Alignment; Sulfonamides | 2015 |
Melatonin attenuates (-)-epigallocatehin-3-gallate-triggered hepatotoxicity without compromising its downregulation of hepatic gluconeogenic and lipogenic genes in mice.
Topics: Animals; Catechin; Forkhead Box Protein O1; Forkhead Transcription Factors; Gluconeogenesis; Lipogenesis; Liver; Male; Melatonin; Mice; Sterol Regulatory Element Binding Protein 1 | 2015 |
Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein.
Topics: Atorvastatin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Catechin; Cells, Cultured; Digoxin; HEK293 Cells; Hepatocytes; Humans; Liver-Specific Organic Anion Transporter 1; Metformin; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Solute Carrier Organic Anion Transporter Family Member 1B3; Tea; Tissue Distribution | 2015 |
Comparison of Cytotoxicity and the Anti-Adipogenic Effect of Green Tea Polyphenols with Epigallocatechin-3-Gallate in 3T3-L1 Preadipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Camellia sinensis; Catechin; CCAAT-Enhancer-Binding Protein-alpha; Cell Differentiation; Dose-Response Relationship, Drug; Mice; Plant Extracts; Polyphenols; Sterol Regulatory Element Binding Protein 1 | 2015 |
Increased intestinal P-glycoprotein expression and activity with progression of diabetes and its modulation by epigallocatechin-3-gallate: Evidence from pharmacokinetic studies.
Topics: Animals; Atorvastatin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Catechin; Diabetes Mellitus, Experimental; Disease Progression; Ileum; Intestinal Absorption; Male; Rats; Sodium-Potassium-Exchanging ATPase; Verapamil | 2015 |
EGCG antagonizes Bortezomib cytotoxicity in prostate cancer cells by an autophagic mechanism.
Topics: Antineoplastic Agents; Autophagy; Bortezomib; Catechin; Cell Line, Tumor; Endoplasmic Reticulum Stress; Eukaryotic Initiation Factor-2; Humans; Leupeptins; Male; Microtubule-Associated Proteins; Prostatic Neoplasms; Proteasome Inhibitors; Transcription Factor CHOP; Up-Regulation | 2015 |
Dressing with epigallocatechin gallate nanoparticles for wound regeneration.
Topics: Animals; Anti-Bacterial Agents; Bandages; Biocompatible Materials; Catechin; Cells, Cultured; Chitosan; Disease Models, Animal; Drug Delivery Systems; Fibroblasts; Gelatin; Gentamicins; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Male; Materials Testing; Nanoparticles; Polyglutamic Acid; Rats; Rats, Sprague-Dawley; Re-Epithelialization; Wound Healing; Wounds and Injuries | 2016 |
Regulation of Transforming Growth Factor β-Activated Kinase Activation by Epigallocatechin-3-Gallate in Rheumatoid Arthritis Synovial Fibroblasts: Suppression of K(63) -Linked Autoubiquitination of Tumor Necrosis Factor Receptor-Associated Factor 6.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Blotting, Western; Catechin; Disease Models, Animal; Female; Fibroblasts; Humans; Immunoprecipitation; In Vitro Techniques; Interleukin-1 Receptor-Associated Kinases; Interleukin-1beta; Interleukin-6; Interleukin-8; Lysine; MAP Kinase Kinase Kinases; Molecular Docking Simulation; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Rats; Rats, Inbred Lew; Synovial Membrane; TNF Receptor-Associated Factor 6; Ubiquitination | 2016 |
Assessing Interactions between Lipophilic and Hydrophilic Antioxidants in Food Emulsions.
Topics: alpha-Tocopherol; Antioxidants; Ascorbic Acid; Catechin; Emulsions; Food; Gallic Acid; Humans; Hydrophobic and Hydrophilic Interactions; Linolenic Acids; Lipid Peroxidation; Lipids; Oxidation-Reduction | 2015 |
Oxidative Stress, Cytotoxicity, and Genotoxicity Induced by Methyl Parathion in Human Gingival Fibroblasts: Protective Role of Epigallocatechin-3-Gallate.
Topics: Apoptosis; Catechin; Cell Line; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Fibroblasts; Gingiva; Humans; Insecticides; Methyl Parathion; Micronucleus Tests; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species | 2015 |
Epigallocatechin-3-Gallate (EGCG) Reduces Rotenone Effect on Stallion Sperm-Zona Pellucida Heterologous Binding.
Topics: Acrosome; Animals; Antioxidants; Catechin; Horses; Male; Rotenone; Sperm Capacitation; Sperm Motility; Sperm-Ovum Interactions; Zona Pellucida | 2015 |
Role of Spm-Cer-S1P signalling pathway in MMP-2 mediated U46619-induced proliferation of pulmonary artery smooth muscle cells: protective role of epigallocatechin-3-gallate.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cardiovascular Agents; Cardiovascular Diseases; Catechin; Cattle; Cell Culture Techniques; Cell Proliferation; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Myocytes, Smooth Muscle; Pulmonary Artery; Vasoconstrictor Agents | 2015 |
Epigallocatechin-3-Gallate Reduces Cytotoxic Effects Caused by Dental Monomers: A Hypothesis.
Topics: Animals; Antioxidants; Apoptosis; Biocompatible Materials; Catechin; Dental Pulp; Dogs; Glutathione; Male; Mice; Mice, Knockout; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Phenotype; Reactive Oxygen Species; Resins, Synthetic; Tooth | 2015 |
Epigallocatechin-3-gallate attenuates the AIM2-induced secretion of IL-1β in human epidermal keratinocytes.
Topics: Caspase 1; Catechin; Cells, Cultured; DNA-Binding Proteins; Humans; Inflammasomes; Interferon-gamma; Interleukin-1beta; Keratinocytes | 2015 |
Amplification by (-)-epigallocatechin gallate and chlorogenic acid of TNF-α-stimulated interleukin-6 synthesis in osteoblasts.
Topics: Animals; Blotting, Western; Catechin; Cell Line; Chlorogenic Acid; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Interleukin-6; Mice; Osteoblasts; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 70-kDa; Tumor Necrosis Factor-alpha | 2015 |
Green tea polyphenol EGCG suppresses osteosarcoma cell growth through upregulating miR-1.
Topics: Apoptosis; Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Crizotinib; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Osteosarcoma; Polyphenols; Proto-Oncogene Proteins c-met; Pyrazoles; Pyridines; Tea | 2016 |
Is there a role for neurotrophic factors and their receptors in augmenting the neuroprotective effect of (-)-epigallocatechin-3-gallate treatment of sciatic nerve crush injury?
Topics: Animals; Brain-Derived Neurotrophic Factor; Catechin; Drug Interactions; Glial Cell Line-Derived Neurotrophic Factor; Male; Nerve Regeneration; Neurons; Neuroprotective Agents; Neurotrophin 3; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Nerve Growth Factor; Sciatic Nerve | 2016 |
Real Time Monitoring of Inhibition of Adipogenesis and Angiogenesis by (-)-Epigallocatechin-3-Gallate in 3T3-L1 Adipocytes and Human Umbilical Vein Endothelial Cells.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Antioxidants; Catechin; CCAAT-Enhancer-Binding Protein-alpha; Cell Proliferation; Human Umbilical Vein Endothelial Cells; Humans; Mice; Neovascularization, Physiologic; Plant Extracts; PPAR gamma; RNA, Messenger; Vascular Endothelial Growth Factor A | 2015 |
Monitoring the Antioxidant Mediated Chemosensitization and ARE-Signaling in Triple Negative Breast Cancer Therapy.
Topics: Animals; Antioxidants; Apoptosis; Blotting, Western; Catechin; Cell Proliferation; Cells, Cultured; Female; Humans; Immunoenzyme Techniques; Immunoprecipitation; Mice; Mice, Nude; NF-E2-Related Factor 2; Oxidative Stress; Response Elements; Signal Transduction; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays | 2015 |
Green Tea Extract Rich in Epigallocatechin-3-Gallate Prevents Fatty Liver by AMPK Activation via LKB1 in Mice Fed a High-Fat Diet.
Topics: AMP-Activated Protein Kinases; Animals; Blotting, Western; Body Weight; Catechin; Diet, High-Fat; Enzyme Activation; Fatty Liver; Male; Mice; Plant Extracts; Protein Serine-Threonine Kinases; Tea | 2015 |
How Epigallocatechin-3-gallate and Tetracycline Interact with the Josephin Domain of Ataxin-3 and Alter Its Aggregation Mode.
Topics: Amyloid; Ataxin-3; Catechin; Humans; Nerve Tissue Proteins; Neuroprotective Agents; Peptides; Repressor Proteins; Spectroscopy, Fourier Transform Infrared; Tetracycline | 2015 |
EGCG Attenuates Uric Acid-Induced Inflammatory and Oxidative Stress Responses by Medicating the NOTCH Pathway.
Topics: Catechin; Chemokine CCL2; Down-Regulation; Human Umbilical Vein Endothelial Cells; Humans; Intercellular Adhesion Molecule-1; Interleukin-6; Oxidative Stress; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Notch; RNA Interference; RNA, Small Interfering; Signal Transduction; Tumor Necrosis Factor-alpha; Up-Regulation; Uric Acid | 2015 |
Bacterial thioredoxin and thioredoxin reductase as mediators for epigallocatechin 3-gallate-induced antimicrobial action.
Topics: Anti-Bacterial Agents; Catechin; Dose-Response Relationship, Drug; Escherichia coli; Microbial Sensitivity Tests; Mutation; Staphylococcus aureus; Structure-Activity Relationship; Thioredoxin-Disulfide Reductase; Thioredoxins; Time Factors | 2016 |
Epigallocatechin-3-gallate shows anti-proliferative activity in HeLa cells targeting tubulin-microtubule equilibrium.
Topics: Antineoplastic Agents; Binding Sites; Catechin; Cell Proliferation; Colchicine; G2 Phase Cell Cycle Checkpoints; HeLa Cells; Humans; Kinetics; M Phase Cell Cycle Checkpoints; Microtubules; Models, Molecular; Polymerization; Protein Conformation; Thermodynamics; Tubulin | 2015 |
Inhibitory Effect of Epigallocatechin Gallate on the Virulence of Clostridium difficile PCR Ribotype 027.
Topics: Animals; Anti-Bacterial Agents; Caenorhabditis elegans; Camellia sinensis; Catechin; Clostridioides difficile; Clostridium Infections; Gene Expression; Genes, Bacterial; Homoserine; Lactones; Mice; Phytotherapy; Plant Extracts; Polymerase Chain Reaction; Quorum Sensing; Ribotyping; Species Specificity; Virulence | 2015 |
Addendum: management of anogenital warts.
Topics: Catechin; Condylomata Acuminata; Humans | 2015 |
Black Tea Extract and Its Theaflavin Derivatives Inhibit the Growth of Periodontopathogens and Modulate Interleukin-8 and β-Defensin Secretion in Oral Epithelial Cells.
Topics: beta-Defensins; Biflavonoids; Catechin; Cell Line; Epithelial Cells; Humans; Interleukin-8; Lipopolysaccharides; Microbial Sensitivity Tests; Mouth; Plant Extracts; Porphyromonas gingivalis; Tea | 2015 |
PLGA-encapsulated tea polyphenols enhance the chemotherapeutic efficacy of cisplatin against human cancer cells and mice bearing Ehrlich ascites carcinoma.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Biflavonoids; Carcinoma, Ehrlich Tumor; Catechin; Cell Count; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Female; Flow Cytometry; Humans; Kinetics; Lactic Acid; Mice; Mitochondria; Nanoparticles; Neovascularization, Pathologic; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyphenols; Reactive Oxygen Species; Tea | 2015 |
Assessment of the activity of directly acting antivirals and other products against different genotypes of hepatitis C virus prevalent in resource-poor countries.
Topics: Antiviral Agents; Catechin; Food Additives; Genotype; Hepacivirus; Hepatitis C; Humans; Nitro Compounds; Prevalence; Silybin; Silymarin; Thiazoles; Virus Replication | 2016 |
Application of Green Tea Catechin for Inducing the Osteogenic Differentiation of Human Dedifferentiated Fat Cells in Vitro.
Topics: Adipocytes; Alkaline Phosphatase; Biomarkers; Calcification, Physiologic; Catechin; Cell Dedifferentiation; Cell Proliferation; Cells, Cultured; Gene Expression; Humans; Osteoblasts; Osteogenesis; RNA, Messenger; Tea | 2015 |
Inhibition of quorum sensing, biofilm, and spoilage potential in Shewanella baltica by green tea polyphenols.
Topics: Animals; Bacterial Proteins; Biofilms; Camellia sinensis; Carbon-Sulfur Lyases; Catechin; Diketopiperazines; Dose-Response Relationship, Drug; Food Preservation; Genes, Bacterial; Homoserine; Lactones; Microbial Sensitivity Tests; Oxidoreductases, N-Demethylating; Perciformes; Polyphenols; Quorum Sensing; Seafood; Shewanella | 2015 |
Comparison of natural crosslinking agents for the stabilization of xenogenic articular cartilage.
Topics: Animals; Cartilage; Cartilage, Articular; Catechin; Collagenases; Cross-Linking Reagents; Drug Evaluation, Preclinical; Grape Seed Extract; Heterografts; Iridoids; Proanthocyanidins; Swine | 2016 |
Transdermal solid delivery of epigallocatechin-3-gallate using self-double-emulsifying drug delivery system as vehicle: Formulation, evaluation and vesicle-skin interaction.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Biocompatible Materials; Biological Availability; Catechin; Cell Line; Cell Survival; Diffusion; Drug Delivery Systems; Emulsions; Excipients; Mice; Particle Size; Skin; Solubility; Spectroscopy, Fourier Transform Infrared; Surface-Active Agents; Viscosity | 2016 |
Epigallocatechin gallate attenuates amyloid β-induced inflammation and neurotoxicity in EOC 13.31 microglia.
Topics: Amyloid beta-Peptides; Animals; Catechin; Cell Line; Gene Expression Regulation; Heme Oxygenase-1; Inflammation; Interleukin-1beta; Interleukin-6; Intracellular Space; MAP Kinase Signaling System; Membrane Proteins; Mice; Microglia; Neurons; Neuroprotective Agents; Neurotoxins; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide Synthase Type II; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 2016 |
Epigallocatechin-3-gallate suppresses alveolar epithelial cell apoptosis in seawater aspiration-induced acute lung injury via inhibiting STAT1-caspase-3/p21 associated pathway.
Topics: Acute Lung Injury; Alveolar Epithelial Cells; Animals; Apoptosis; Caspase 3; Catechin; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Humans; Lung; Male; Phosphorylation; Pulmonary Edema; Rats, Sprague-Dawley; Respiratory Aspiration; Seawater; Signal Transduction; STAT1 Transcription Factor | 2016 |
A 3-day EGCG-supplementation reduces interstitial lactate concentration in skeletal muscle of overweight subjects.
Topics: Adipose Tissue; Catechin; Dietary Supplements; Energy Metabolism; Female; Gene Expression Regulation; Humans; Lactic Acid; Lipolysis; Male; Metabolome; Metabolomics; Muscle, Skeletal; Overweight; Oxidation-Reduction; Time Factors | 2015 |
Theaflavin-3, 3'-digallate decreases human ovarian carcinoma OVCAR-3 cell-induced angiogenesis via Akt and Notch-1 pathways, not via MAPK pathways.
Topics: Biflavonoids; Carcinoma; Catechin; Cell Line, Tumor; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mitogen-Activated Protein Kinase Kinases; Neovascularization, Pathologic; Oncogene Protein v-akt; Ovarian Neoplasms; Proto-Oncogene Proteins c-myc; Receptor, Notch1; Signal Transduction; Vascular Endothelial Growth Factor A | 2016 |
EGCG attenuates atherosclerosis through the Jagged-1/Notch pathway.
Topics: Animals; Apolipoproteins E; Apoptosis; Atherosclerosis; Calcium-Binding Proteins; Catechin; Gene Expression Regulation, Enzymologic; Human Umbilical Vein Endothelial Cells; Humans; Intercellular Signaling Peptides and Proteins; Jagged-1 Protein; Lipoproteins, LDL; Membrane Proteins; Mice; Mice, Knockout; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Receptors, Notch; Serrate-Jagged Proteins; Signal Transduction | 2016 |
EGCG/gelatin-doxorubicin gold nanoparticles enhance therapeutic efficacy of doxorubicin for prostate cancer treatment.
Topics: Antibiotics, Antineoplastic; Catechin; Cell Line, Tumor; Doxorubicin; Gelatin; Gold; Humans; Male; Metal Nanoparticles | 2016 |
Effect of adjunctive application of epigallocatechin-3-gallate and ethanol-wet bonding on adhesive-dentin bonds.
Topics: Acid Etching, Dental; Adhesives; Catechin; Composite Resins; Dental Bonding; Dentin; Dentin-Bonding Agents; Ethanol; Humans; Methacrylates; Molar, Third; Random Allocation; Water | 2016 |
N- and S-homocysteinylation reduce the binding of human serum albumin to catechins.
Topics: Aminoacylation; Catechin; Cysteine; Electrophoresis, Capillary; Homocysteine; Humans; Hyperhomocysteinemia; Kinetics; Ligands; Lysine; Protein Processing, Post-Translational; Serum Albumin; Serum Albumin, Human | 2017 |
Polyphenolic Secondary Metabolites Synergize the Activity of Commercial Antibiotics against Clinical Isolates of β-Lactamase-producing Klebsiella pneumoniae.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Caffeic Acids; Catechin; Ciprofloxacin; Drug Synergism; Ellagic Acid; Gentamicins; Klebsiella pneumoniae; Microbial Sensitivity Tests; Phytochemicals; Polyphenols; Quercetin; Reserpine; Tetracycline | 2016 |
Characterization and cloning of laccase gene from Hericium coralloides NBRC 7716 suitable for production of epitheaflagallin 3-O-gallate.
Topics: Amino Acid Sequence; Basidiomycota; Benzocycloheptenes; Catechin; Cloning, Molecular; Fungal Proteins; Gallic Acid; Genes, Fungal; Hot Temperature; Hydrogen-Ion Concentration; Laccase; Molecular Sequence Data; Molecular Structure; Oxidation-Reduction; Phenols; Phosphoglycerate Kinase; Polyphenols; Protein Stability; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Substrate Specificity | 2016 |
Green tea extract as a treatment for patients with wild-type transthyretin amyloidosis: an observational study.
Topics: Administration, Oral; Aged; Aged, 80 and over; Amyloid; Amyloid Neuropathies, Familial; Catechin; Cohort Studies; Humans; Hypertrophy, Left Ventricular; Male; Middle Aged; Plant Extracts; Tea | 2015 |
Green Tea Polyphenol Prevents Diabetic Rats From Acute Kidney Injury After Cardiopulmonary Bypass.
Topics: Acute Kidney Injury; Administration, Oral; Animals; Biopsy, Needle; Cardiopulmonary Bypass; Catechin; Diabetes Mellitus, Experimental; Disease Models, Animal; Follow-Up Studies; Immunohistochemistry; Kidney Function Tests; Male; Polyphenols; Preoperative Care; Random Allocation; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reference Values; Risk Assessment; Tea; Treatment Outcome | 2016 |
Determination and quality evaluation of green tea extracts through qualitative and quantitative analysis of multi-components by single marker (QAMS).
Topics: Caffeine; Catechin; Food Quality; Gallic Acid; Tea | 2016 |
The Amyloid Fibril-Forming Properties of the Amphibian Antimicrobial Peptide Uperin 3.5.
Topics: Amino Acid Sequence; Amphibians; Amyloid; Animals; Antimicrobial Cationic Peptides; Catechin; Cell Survival; Circular Dichroism; PC12 Cells; Protein Structure, Secondary; Rats; Spectrometry, Mass, Electrospray Ionization | 2016 |
Cellular determinants involving mitochondrial dysfunction, oxidative stress and apoptosis correlate with the synergic cytotoxicity of epigallocatechin-3-gallate and menadione in human leukemia Jurkat T cells.
Topics: Apoptosis; Calcium; Catechin; Cell Survival; Humans; Jurkat Cells; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Stress; Reactive Oxygen Species; Vitamin K 3 | 2016 |
Stereochemistry of the Black Tea Pigments Theacitrins A and C.
Topics: Camellia sinensis; Catechin; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Pigments, Biological; Polyphenols; Tea | 2016 |
The polyphenol (-)-epigallocatechin-3-gallate prevents apoA-IIowa amyloidosis in vitro and protects human embryonic kidney 293 cells against amyloid cytotoxicity.
Topics: Amyloid; Amyloidosis; Apolipoprotein A-I; Catechin; Cell Survival; Drug Evaluation, Preclinical; HEK293 Cells; Humans; Protein Aggregation, Pathological; Protein Structure, Secondary; Reactive Oxygen Species | 2016 |
Galloylated proanthocyanidins from shea (Vitellaria paradoxa) meal have potent anthelmintic activity against Ascaris suum.
Topics: Animals; Anthelmintics; Ascaris suum; Catechin; Chromatography, High Pressure Liquid; Ericaceae; Flavonoids; Gallic Acid; Molecular Structure; Proanthocyanidins; Seeds; Swine | 2016 |
Modulation of hexavalent chromium-induced genotoxic damage in peripheral blood of mice by epigallocatechin-3-gallate (EGCG) and its relationship to the apoptotic activity.
Topics: Animals; Antimutagenic Agents; Apoptosis; Catechin; Cell Survival; Chromium; Chromium Compounds; DNA Damage; Environmental Pollutants; Erythrocytes; Male; Mice; Mice, Inbred ICR; Micronucleus Tests; Mutagens; Necrosis | 2016 |
Association of Catechin Molecules in Water: Quantitative Binding Study and Complex Structure Analysis.
Topics: Catechin; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Stereoisomerism; Tea; Water | 2016 |
The green tea polyphenol EGCG potentiates the antiproliferative activity of sunitinib in human cancer cells.
Topics: Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Breast Neoplasms; Catechin; Cell Proliferation; Drug Synergism; Drug Therapy, Combination; Female; Humans; Immunoenzyme Techniques; Indoles; Insulin Receptor Substrate Proteins; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Prognosis; Pyrroles; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sunitinib; Tea; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2016 |
Reduction in Autophagy by (-)-Epigallocatechin-3-Gallate (EGCG): a Potential Mechanism of Prevention of Mitochondrial Dysfunction After Subarachnoid Hemorrhage.
Topics: Animals; Autophagy; Catechin; Cell Survival; Dose-Response Relationship, Drug; Male; Mice; Mitochondria; Neuroprotective Agents; PC12 Cells; Rats; Subarachnoid Hemorrhage | 2017 |
Epigallocatechin-3-gallate protects against tumor necrosis factor alpha induced inhibition of osteogenesis of mesenchymal stem cells.
Topics: Catechin; Cell Differentiation; Cell Survival; Cells, Cultured; Humans; Immunologic Factors; Mesenchymal Stem Cells; Osteogenesis; Tumor Necrosis Factor-alpha | 2016 |
Differential effects of Epigallocatechin-3-gallate containing supplements on correcting skeletal defects in a Down syndrome mouse model.
Topics: Absorptiometry, Photon; Animals; Bone and Bones; Catechin; Dietary Supplements; Disease Models, Animal; Down Syndrome; Female; Femur; Male; Mice, Inbred C57BL; Mice, Mutant Strains; X-Ray Microtomography | 2016 |
Epigallocatechin-3-O-gallate up-regulates microRNA-let-7b expression by activating 67-kDa laminin receptor signaling in melanoma cells.
Topics: Animals; Catechin; Cell Line, Tumor; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HMGA2 Protein; Humans; Melanoma; Mice; MicroRNAs; Protein Phosphatase 2; Receptors, Laminin; Ribosomal Proteins; Signal Transduction | 2016 |
Identification of (-)-epigallocatechin-3-gallate as a potential agent for blocking infection by grass carp reovirus.
Topics: Animals; Carps; Catechin; Cells, Cultured; Dose-Response Relationship, Drug; Kidney; Reoviridae; Virus Attachment | 2016 |
Quantitation of Alpha-Glucosidase Activity Using Fluorinated Carbohydrate Array and MALDI-TOF-MS.
Topics: Acarbose; alpha-Glucosidases; Carbohydrates; Catechin; Enzyme Assays; Halogenation; Inhibitory Concentration 50; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2016 |
Epigallocatechin-3-gallate induces oxidative phosphorylation by activating cytochrome c oxidase in human cultured neurons and astrocytes.
Topics: Adenosine Triphosphate; Astrocytes; Blotting, Western; Brain; Catechin; Cell Proliferation; Cell Respiration; Cells, Cultured; Electron Transport Complex IV; Fetus; Humans; Membrane Potential, Mitochondrial; Mitochondria; Neurons; Neuroprotective Agents; Oxidation-Reduction; Oxidative Phosphorylation; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2016 |
Effects of exercise and dietary epigallocatechin gallate and β-alanine on skeletal muscle in aged mice.
Topics: Age Factors; Animals; beta-Alanine; Catechin; Dietary Supplements; Male; Mice; Mice, Inbred BALB C; Muscle, Skeletal; Running | 2016 |
Metal chelation, radical scavenging and inhibition of Aβ₄₂ fibrillation by food constituents in relation to Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Brain; Catechin; Chelating Agents; Curcumin; Free Radical Scavengers; Gallic Acid; Humans; Metals; Peptide Fragments | 2016 |
Interactions between milk fat globules and green tea catechins.
Topics: Catechin; Glycolipids; Glycoproteins; Hydrophobic and Hydrophilic Interactions; Lipid Droplets; Microscopy, Electron, Transmission; Spectroscopy, Fourier Transform Infrared; Tea | 2016 |
EGCG ameliorates the hypoxia-induced apoptosis and osteogenic differentiation reduction of mesenchymal stem cells via upregulating miR-210.
Topics: Alkaline Phosphatase; Apoptosis; Bone Morphogenetic Protein 2; Catechin; Cell Hypoxia; Collagen Type I; Core Binding Factor Alpha 1 Subunit; Ephrin-A3; Gene Expression Regulation; Humans; Mesenchymal Stem Cells; MicroRNAs; Osteogenesis; Up-Regulation | 2016 |
Inhibitory effects of selected dietary flavonoids on the formation of total heterocyclic amines and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in roast beef patties and in chemical models.
Topics: Acetaldehyde; Amines; Animals; Antioxidants; Catechin; Cattle; Flavonoids; Heterocyclic Compounds; Imidazoles; Meat Products; Phlorhizin; Quercetin; Red Meat | 2016 |
Bioanalytical LC/MS study of potential bacterial transglycosylation inhibitors.
Topics: Anti-Bacterial Agents; Camellia sinensis; Catechin; Chromatography, Liquid; Drug Discovery; Mass Spectrometry; Penicillin-Binding Proteins; Plant Extracts; Salvia; Staphylococcus aureus; Thymus Plant; Triterpenes; Uridine Diphosphate N-Acetylmuramic Acid; Ursolic Acid | 2016 |
Targeted intracellular protein delivery based on hyaluronic acid-green tea catechin nanogels.
Topics: Animals; Catechin; Cell Survival; Chickens; Dimerization; Drug Delivery Systems; Dynamic Light Scattering; Flow Cytometry; Granzymes; HCT116 Cells; Hep G2 Cells; Humans; Hyaluronan Receptors; Hyaluronic Acid; Intracellular Space; Muramidase; Nanogels; Polyethylene Glycols; Polyethyleneimine; Spectrometry, Fluorescence; Tea | 2016 |
EGCG induces lung cancer A549 cell apoptosis by regulating Ku70 acetylation.
Topics: A549 Cells; Acetylation; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Caspase 3; Catechin; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Ku Autoantigen; Lung Neoplasms | 2016 |
Estrogen receptor-α36 is involved in epigallocatechin-3-gallate induced growth inhibition of ER-negative breast cancer stem/progenitor cells.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Catechin; Cell Transformation, Neoplastic; Cells, Cultured; Down-Regulation; Estrogen Receptor alpha; Gene Expression; Humans; Neoplastic Stem Cells | 2016 |
Epigallocatechin Gallate Attenuates Partial Bladder Outlet Obstruction-induced Bladder Injury via Suppression of Endoplasmic Reticulum Stress-related Apoptosis-In Vivo Study.
Topics: Animals; Antioxidants; Apoptosis; Catechin; Endoplasmic Reticulum Stress; Female; Random Allocation; Rats; Rats, Sprague-Dawley; Urinary Bladder Neck Obstruction | 2016 |
Implication of Green Tea as a Possible Therapeutic Approach for Parkinson Disease.
Topics: Animals; Catechin; Humans; Neuroprotective Agents; Parkinson Disease; Tea | 2016 |
Chiral Recognition of Diketopiperazine Cyclo(Pro-Gly) and Propranolol Using (-)-Epigallocatechin-3-O-gallate.
Topics: Catechin; Diketopiperazines; Molecular Structure; Peptides, Cyclic; Propranolol; Proton Magnetic Resonance Spectroscopy; Reference Standards | 2016 |
Quantitative Evaluation of Cancer Cell Adhesion to Self-Assembled Monolayer-Patterned Substrates by Reflection Interference Contrast Microscopy.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Adhesion; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Melanoma, Experimental; Mice; Microscopy, Interference; Neoplasm Metastasis; Neoplasms | 2016 |
The Effect of (-)-Epigallocatechin-3-Gallate on IL-1β Induced IL-8 Expression in Orbital Fibroblast from Patients with Thyroid-Associated Ophthalmopathy.
Topics: Antioxidants; Catechin; Fibroblasts; Graves Ophthalmopathy; Humans; Interleukin-1beta; Interleukin-8; MAP Kinase Signaling System; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species | 2016 |
Green tea catechins potentiate the effect of antibiotics and modulate adherence and gene expression in Porphyromonas gingivalis.
Topics: Anti-Bacterial Agents; Bacterial Adhesion; Catechin; Drug Synergism; Epithelial Cells; Gene Expression; Periodontal Diseases; Plant Extracts; Polyphenols; Porphyromonas gingivalis; Quorum Sensing; Serine Proteases; Tea; Virulence Factors | 2016 |
Epigallocatechin Gallate Extends the Therapeutic Window of Recombinant Tissue Plasminogen Activator Treatment in Ischemic Rats.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Catechin; Disease Models, Animal; Drug Therapy, Combination; Fibrinolytic Agents; Gene Expression Regulation; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 9; Neuroprotective Agents; Permeability; Plasminogen Activator Inhibitor 1; Rats; Rats, Sprague-Dawley; Sensory Gating; Time Factors; Tissue Plasminogen Activator; Treatment Outcome | 2016 |
Self-assembled ternary complexes stabilized with hyaluronic acid-green tea catechin conjugates for targeted gene delivery.
Topics: Catechin; DNA; Endocytosis; Green Fluorescent Proteins; HCT116 Cells; HEK293 Cells; Humans; Hyaluronan Receptors; Hyaluronic Acid; Plasmids; Polyethyleneimine; Tea; Transfection | 2016 |
Targeting HO-1 by Epigallocatechin-3-Gallate Reduces Contrast-Induced Renal Injury via Anti-Oxidative Stress and Anti-Inflammation Pathways.
Topics: Animals; Antioxidants; Apoptosis; Carrier Proteins; Catechin; Contrast Media; Down-Regulation; Heme Oxygenase (Decyclizing); In Situ Nick-End Labeling; Inflammasomes; Inflammation; Kidney; Kidney Diseases; Male; Microscopy, Fluorescence; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Protoporphyrins; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Up-Regulation | 2016 |
Cytotoxicity and effect on protease activity of copolymer extracts containing catechin.
Topics: Animals; Catechin; Chlorhexidine; Composite Resins; Dental Caries; Dental Materials; Dentin; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Odontoblasts; Peptide Hydrolases; Polymers; Protease Inhibitors; Resins, Synthetic | 2016 |
EGCG prevents PCB-126-induced endothelial cell inflammation via epigenetic modifications of NF-κB target genes in human endothelial cells.
Topics: Acetylation; Catechin; Cell Line; Cell Nucleus; Chromatin; Endothelium, Vascular; Gene Expression Regulation; Humans; Inflammation; Inflammation Mediators; Polychlorinated Biphenyls; Protein Transport; Transcription Factor RelA | 2016 |
(-)-Epigallocatechin-3-Gallate Enhances Hepatitis C Virus Double-Stranded RNA Intermediates-Triggered Innate Immune Responses in Hepatocytes.
Topics: Antiviral Agents; Catechin; Cell Line, Tumor; DEAD Box Protein 58; Hepacivirus; Hepatocytes; Humans; Immunity, Innate; Interferons; Interleukins; Receptors, Immunologic; RNA, Double-Stranded; RNA, Viral; Signal Transduction; Toll-Like Receptor 3 | 2016 |
EGCG decreases binding of calcium oxalate monohydrate crystals onto renal tubular cells via decreased surface expression of alpha-enolase.
Topics: Animals; Binding Sites; Calcium Oxalate; Catechin; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Madin Darby Canine Kidney Cells; Phosphopyruvate Hydratase; Structure-Activity Relationship; Surface Properties | 2016 |
EGCG in Green Tea Induces Aggregation of HMGB1 Protein through Large Conformational Changes with Polarized Charge Redistribution.
Topics: Binding Sites; Catechin; Cysteine; HMGB1 Protein; Humans; Molecular Conformation; Molecular Dynamics Simulation; Molecular Structure; Protein Aggregates; Protein Aggregation, Pathological; Protein Binding; Protein Domains; Protein Multimerization; Static Electricity; Tea | 2016 |
The single and synergistic effects of the major tea components caffeine, epigallocatechin-3-gallate and L-theanine on rat sperm viability.
Topics: Animals; Caffeine; Camellia sinensis; Catechin; Cell Survival; Glutamates; Male; Plant Extracts; Rats; Rats, Wistar; Spermatozoa | 2016 |
Syntheses of methylated catechins and theaflavins using 2-nitrobenzenesulfonyl group to protect and deactivate phenol.
Topics: Antioxidants; Benzenesulfonates; Biflavonoids; Catechin; Methylation; Oxidation-Reduction; Polyphenols; Structure-Activity Relationship | 2016 |
Aging is associated with hypermethylation of autophagy genes in macrophages.
Topics: Aging; Animals; Autophagosomes; Autophagy; Autophagy-Related Protein 5; Catechin; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Humans; Macrophages; Mice; Microtubule-Associated Proteins; RNA, Small Interfering | 2016 |
Epigallocatechin-3-Gallate Inhibits Ethanol-Induced Apoptosis Through Neurod1 Regulating CHOP Expression in Pancreatic β-Cells.
Topics: Animals; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Blotting, Western; Catechin; Cell Proliferation; Cells, Cultured; Central Nervous System Depressants; Chromatin Immunoprecipitation; Ethanol; Gene Expression Regulation; Insulin-Secreting Cells; Mice; Nerve Tissue Proteins; Neuroprotective Agents; Rats; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factor CHOP | 2016 |
Green tea compound epigallo-catechin-3-gallate (EGCG) increases neuronal survival in adult hippocampal neurogenesis in vivo and in vitro.
Topics: Animals; Catechin; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Doublecortin Domain Proteins; Doublecortin Protein; Hippocampus; Male; Mice, Inbred BALB C; Microtubule-Associated Proteins; Neural Stem Cells; Neurogenesis; Neurons; Neuropeptides; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Tea | 2016 |
The Effect of Epigallocatechin Gallate on Flap Viability of Rat Perforator Abdominal Flaps.
Topics: Abdomen; Angiogenesis Inducing Agents; Animals; Catechin; Disease Models, Animal; Female; Graft Survival; Perforator Flap; Plastic Surgery Procedures; Rats; Rats, Wistar; Regional Blood Flow | 2016 |
Encapsulation of (-)-epigallocatechin gallate into liposomes and into alginate or chitosan microparticles reinforced with liposomes.
Topics: Alginates; Antioxidants; Calorimetry, Differential Scanning; Catechin; Chitosan; Dietary Supplements; Food Additives; Food Handling; Food Preservatives; Food Storage; Fruit and Vegetable Juices; Glucuronic Acid; Hexuronic Acids; Hydrogen-Ion Concentration; Liposomes; Microspheres; Particle Size; Porosity; Solubility; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Surface Properties | 2016 |
Biopharmaceutical evaluation of epigallocatechin gallate-loaded cationic lipid nanoparticles (EGCG-LNs): In vivo, in vitro and ex vivo studies.
Topics: Animals; Catechin; Cetrimonium; Cetrimonium Compounds; Chickens; Chorioallantoic Membrane; Delayed-Action Preparations; Drug Liberation; Emulsions; Eye; Lipids; Male; Nanoparticles; Permeability; Quaternary Ammonium Compounds; Rabbits | 2016 |
Epigallocatechin-3-gallate inhibits transforming-growth-factor-β1-induced collagen synthesis by suppressing early growth response-1 in human buccal mucosal fibroblasts.
Topics: Anthracenes; Benzamides; Catechin; Cells, Cultured; Collagen Type I; Dioxoles; Early Growth Response Protein 1; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Humans; Mouth Mucosa; Oral Submucous Fibrosis; Signal Transduction; Transforming Growth Factor beta1 | 2017 |
Elevated plasma and urinary concentrations of green tea catechins associated with improved plasma lipid profile in healthy Japanese women.
Topics: Adipose Tissue; Adult; Aged; Asian People; Biomarkers; Blood Glucose; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Catechin; Cholesterol, HDL; Cholesterol, LDL; Female; Humans; Japan; Middle Aged; Plant Extracts; Tea; Triglycerides | 2016 |
Bioactive compounds isolated from apple, tea, and ginger protect against dicarbonyl induced stress in cultured human retinal epithelial cells.
Topics: Catechin; Catechols; Cell Line; Epithelial Cells; Fatty Alcohols; Glutathione; Glycation End Products, Advanced; Heme Oxygenase-1; Humans; Lysine; Malus; NF-E2-Related Factor 2; Phloretin; Phytochemicals; Protective Agents; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Retinal Pigment Epithelium; Tea; Zingiber officinale | 2016 |
Epigallocatechin-3-gallate attenuates apoptosis and autophagy in concanavalin A-induced hepatitis by inhibiting BNIP3.
Topics: Animals; Apoptosis; Autophagy; Catechin; Chemical and Drug Induced Liver Injury; Concanavalin A; Cytokines; Janus Kinase 1; Janus Kinase 2; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mitochondrial Proteins; Signal Transduction; STAT3 Transcription Factor | 2016 |
Epigallocatechin-3-gallate targets cancer stem-like cells and enhances 5-fluorouracil chemosensitivity in colorectal cancer.
Topics: Animals; Antineoplastic Agents; Catechin; Cell Line, Tumor; Colorectal Neoplasms; Drug Resistance, Neoplasm; Fluorouracil; Humans; Mice; Mice, Nude; Neoplastic Stem Cells | 2016 |
Laminin Receptor-Avid Nanotherapeutic EGCg-AuNPs as a Potential Alternative Therapeutic Approach to Prevent Restenosis.
Topics: Anti-Inflammatory Agents; Antioxidants; Catechin; Cell Line; Cell Movement; Cell Proliferation; Coronary Restenosis; Drug Carriers; Endothelial Cells; Gold; Human Umbilical Vein Endothelial Cells; Humans; Metal Nanoparticles; Myocytes, Smooth Muscle; Receptors, Laminin; Ribosomal Proteins | 2016 |
Inhibition of Nickel Nanoparticles-Induced Toxicity by Epigallocatechin-3-Gallate in JB6 Cells May Be through Down-Regulation of the MAPK Signaling Pathways.
Topics: Animals; Apoptosis; Catechin; Cell Count; Cell Cycle; Cell Line; Cell Shape; Cell Survival; Down-Regulation; Luciferases; MAP Kinase Signaling System; Metal Nanoparticles; Mice; NF-kappa B; Nickel; Oxidative Stress; Reactive Oxygen Species; Transcription Factor AP-1 | 2016 |
Nitric oxide pathway activity modulation alters the protective effects of (-)Epigallocatechin-3-gallate on reserpine-induced impairment in rats.
Topics: Animals; Arginine; Catechin; Discrimination, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exploratory Behavior; Glutathione; Hippocampus; Lipid Peroxidation; Male; Memory Disorders; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Reserpine; Signal Transduction; Smell; Superoxide Dismutase | 2016 |
Biological and Mechanistic Characterization of Novel Prodrugs of Green Tea Polyphenol Epigallocatechin Gallate Analogs in Human Leiomyoma Cell Lines.
Topics: Apoptosis; Blotting, Western; Catechin; Cell Movement; Cell Proliferation; Female; Fluorescent Antibody Technique; Humans; Leiomyoma; Neovascularization, Pathologic; Prodrugs; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tea; Tumor Cells, Cultured; Uterine Neoplasms | 2016 |
Epigallocatechin-3-gallate ameliorates autoimmune arthritis by reciprocal regulation of T helper-17 regulatory T cells and inhibition of osteoclastogenesis by inhibiting STAT3 signaling.
Topics: Animals; Antioxidants; Arthritis, Experimental; Autoimmune Diseases; Catechin; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Male; Mice; Mice, Inbred DBA; Mice, Knockout; Osteoclasts; Osteogenesis; Signal Transduction; STAT3 Transcription Factor; T-Lymphocytes, Regulatory; Th17 Cells | 2016 |
Effect of the consumption of β-lactoglobulin and epigallocatechin-3-gallate with or without calcium on glucose tolerance in C57BL/6 mice.
Topics: Animals; Blood Glucose; Calcium; Catechin; Glucose; Glucose Intolerance; Lactoglobulins; Male; Mice; Mice, Inbred C57BL; Random Allocation | 2016 |
The polyphenols resveratrol and epigallocatechin-3-gallate restore the severe impairment of mitochondria in hippocampal progenitor cells from a Down syndrome mouse model.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinase Kinases; Animals; Antioxidants; Catechin; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Down Syndrome; Female; Hippocampus; Male; Mice; Mitochondria; Neural Stem Cells; Neurogenesis; Neuroprotective Agents; Protein Kinases; Resveratrol | 2016 |
Epigallocatechin-3-Gallate Inhibition of Myeloperoxidase and Its Counter-Regulation by Dietary Iron and Lipocalin 2 in Murine Model of Gut Inflammation.
Topics: Acute-Phase Proteins; Animals; Antioxidants; Catechin; Dextran Sulfate; Disease Models, Animal; Humans; Inflammation; Iron, Dietary; Lipocalin-2; Lipocalins; Mice, Inbred C57BL; Oncogene Proteins; Peroxidase; Proto-Oncogene Proteins; Tea | 2016 |
Epigallocatechin gallate inhibits hepatitis B virus via farnesoid X receptor alpha.
Topics: Catechin; Cell Line, Tumor; Hep G2 Cells; Hepatitis B virus; Humans; Receptors, Cytoplasmic and Nuclear; Tea | 2016 |
The green tea polyphenol EGCG alleviates maternal diabetes-induced neural tube defects by inhibiting DNA hypermethylation.
Topics: Animals; Catechin; CpG Islands; Diabetes Mellitus, Experimental; Diabetes, Gestational; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA-Binding Proteins; Embryo, Mammalian; Female; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Mice, Inbred C57BL; Neural Tube Defects; PAX3 Transcription Factor; Pregnancy; Proteins; Transcription Factors | 2016 |
[Biomodifying effect of epigallocatechin-3-gallate on dentine substrate splicing surface].
Topics: Acid Etching, Dental; Catechin; Collagen; Collagenases; Composite Resins; Dental Bonding; Dental Cements; Dental Pulp; Dentin; Dentin Permeability; Dentin-Bonding Agents; Glutaral; Hydrogen-Ion Concentration; Hydrolysis; Methacrylates; Microscopy, Electron, Scanning; Pressure; Resin Cements; Serum Albumin, Bovine; Tensile Strength; Time Factors | 2016 |
Quantitative thermophoretic study of disease-related protein aggregates.
Topics: alpha-Synuclein; Calorimetry; Catechin; Fluorescent Dyes; Microscopy, Atomic Force; Protein Aggregates; Protein Binding; Static Electricity; Temperature | 2016 |
Certain (-)-epigallocatechin-3-gallate (EGCG) auto-oxidation products (EAOPs) retain the cytotoxic activities of EGCG.
Topics: Animals; Anticarcinogenic Agents; Camellia sinensis; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromatography, High Pressure Liquid; Cysteine; Dose-Response Relationship, Drug; Humans; Hydrogen Peroxide; Mice; Oxidation-Reduction; Plant Leaves; Tea; Thioredoxin-Disulfide Reductase | 2016 |
Separation of catechins and O-methylated (-)-epigallocatechin gallate using polyamide thin-layer chromatography.
Topics: Catechin; Chromatography, Thin Layer; Methylation; Nylons | 2016 |
Green tea polyphenol epigallocatechin-3-gallate improves epithelial barrier function by inducing the production of antimicrobial peptide pBD-1 and pBD-2 in monolayers of porcine intestinal epithelial IPEC-J2 cells.
Topics: Animals; Anti-Infective Agents; beta-Defensins; Catechin; Cell Line; Epithelial Cells; Escherichia coli; Intestinal Mucosa; Intestines; p38 Mitogen-Activated Protein Kinases; Polyphenols; Swine; Tea | 2016 |
The green tea polyphenol EGCG inhibits E. coli biofilm formation by impairing amyloid curli fibre assembly and downregulating the biofilm regulator CsgD via the σ(E) -dependent sRNA RybB.
Topics: Amyloid; Anti-Infective Agents; Bacterial Adhesion; Bacterial Proteins; Biofilms; Catechin; Down-Regulation; Escherichia coli; Escherichia coli Proteins; Promoter Regions, Genetic; RNA, Messenger; RNA, Small Untranslated; Sigma Factor; Tea; Trans-Activators | 2016 |
In Silico Analysis of Green Tea Polyphenols as Inhibitors of AChE and BChE Enzymes in Alzheimer's Disease Treatment.
Topics: Acetylcholine; Acetylcholinesterase; Alzheimer Disease; Amino Acid Sequence; Butyrylcholinesterase; Catechin; Cholinesterase Inhibitors; Humans; Molecular Docking Simulation; Nootropic Agents; Phytochemicals; Polyphenols; Protein Binding; Synaptic Transmission; Tea | 2016 |
EGCG stabilizes growth cone filopodia and impairs retinal ganglion cell axon guidance.
Topics: Animals; Axon Guidance; Axons; Brain; Catechin; Chorionic Gonadotropin; Diencephalon; Embryo, Nonmammalian; Female; Growth Cones; Humans; In Situ Hybridization; Neurogenesis; Pseudopodia; Retina; Retinal Ganglion Cells; Xenopus | 2016 |
Utilization of interfacial engineering to improve physicochemical stability of β-carotene emulsions: Multilayer coatings formed using protein and protein-polyphenol conjugates.
Topics: beta Carotene; Catechin; Chemical Phenomena; Chlorogenic Acid; Electrophoresis, Polyacrylamide Gel; Emulsions; Food Technology; Hydrogen-Ion Concentration; Lactoferrin; Polyphenols | 2016 |
Microneedle-mediated intradermal delivery of epigallocatechin-3-gallate.
Topics: Administration, Cutaneous; Animals; Catechin; In Vitro Techniques; Needles; Skin; Swine | 2016 |
Formulation, characteristics and antiatherogenic bioactivities of CD36-targeted epigallocatechin gallate (EGCG)-loaded nanoparticles.
Topics: Atherosclerosis; Catechin; CD36 Antigens; Humans; Nanoparticles | 2016 |
Effects of epigallocatechin-3-gallate on proliferation and differentiation of mouse cochlear neural stem cells: Involvement of PI3K/Akt signaling pathway.
Topics: Animals; Calcium; Catechin; Cell Differentiation; Cell Proliferation; Cell Survival; Cells, Cultured; Cochlea; Gene Expression Regulation; Mice; Neural Stem Cells; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction | 2016 |
An in vitro evaluation of epigallocatechin gallate (eGCG) as a biocompatible inhibitor of ricin toxin.
Topics: Animals; Antidotes; Biological Transport; Catechin; Cell Survival; Chlorocebus aethiops; Cloning, Molecular; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Macrophages; Protein Binding; Ricin; Transfection; Vero Cells | 2016 |
Epigallocatechin gallate attenuates cardiopulmonary bypass-associated lung injury.
Topics: Animals; Antioxidants; Apoptosis Inducing Factor; Camellia sinensis; Cardiopulmonary Bypass; Catechin; Drug Evaluation, Preclinical; Female; Immunohistochemistry; Lung; Lung Injury; Male; Phytotherapy; Plant Extracts; Poly Adenosine Diphosphate Ribose; Swine; Tumor Necrosis Factor-alpha; Tyrosine | 2016 |
Long-Term Effects of (-)-Epigallocatechin Gallate (EGCG) on Pristane-Induced Arthritis (PIA) in Female Dark Agouti Rats.
Topics: Animals; Arthritis; Biomarkers; Catechin; Chronic Disease; Female; Inflammation; Methotrexate; Orosomucoid; Peroxidase; Rats; Terpenes | 2016 |
EGCG Inhibited Lipofuscin Formation Based on Intercepting Amyloidogenic β-Sheet-Rich Structure Conversion.
Topics: Aging; Animals; Catechin; Female; Lipofuscin; Mice; PC12 Cells; Rats | 2016 |
Three New Oxidation Products Produced from Epigallocatechin-3- O-gallate and Epicatechin-3-O-gallate.
Topics: Camellia sinensis; Catechin; Molecular Structure; Oxidation-Reduction | 2016 |
Mutations in troponin T associated with Hypertrophic Cardiomyopathy increase Ca(2+)-sensitivity and suppress the modulation of Ca(2+)-sensitivity by troponin I phosphorylation.
Topics: Actin Cytoskeleton; Animals; Calcium; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic; Catechin; Dose-Response Relationship, Drug; Heart; Humans; Mice; Mice, Transgenic; Mutation; Myocardial Contraction; Phosphorylation; Recombinant Proteins; Troponin I; Troponin T | 2016 |
(-)-Epigallocatechin Gallate Inhibits Asymmetric Dimethylarginine-Induced Injury in Human Brain Microvascular Endothelial Cells.
Topics: Antioxidants; Apoptosis; Arginine; Brain; Catechin; Cell Survival; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Microvessels | 2016 |
Epigallocatechin Gallate Remodels Fibrils of Lattice Corneal Dystrophy Protein, Facilitating Proteolytic Degradation and Preventing Formation of Membrane-Permeabilizing Species.
Topics: Amyloid; Antioxidants; Catechin; Cell Membrane Permeability; Corneal Dystrophies, Hereditary; Extracellular Matrix Proteins; Humans; Liposomes; Peptide Hydrolases; Protein Domains; Protein Multimerization; Proteolysis; Transforming Growth Factor beta | 2016 |
Oxidative Deamination of Serum Albumins by (-)-Epigallocatechin-3-O-Gallate: A Potential Mechanism for the Formation of Innate Antigens by Antioxidants.
Topics: Animals; Antigens; Antioxidants; Catechin; Chromatography, Liquid; Click Chemistry; Deamination; Female; Immunity, Innate; Mice; Mice, Inbred BALB C; Oxidation-Reduction; Serum Albumin; Spectrometry, Mass, Electrospray Ionization | 2016 |
Selective toxicity of Catechin-a natural flavonoid towards bacteria.
Topics: Antioxidants; Bacillus subtilis; Catechin; Dose-Response Relationship, Drug; Escherichia coli; Flavonoids; Gram-Negative Bacteria; Gram-Positive Bacteria; Inhibitory Concentration 50; Polyphenols; Reactive Oxygen Species | 2016 |
Epigallocatechin-3-gallate decreases the transport and metabolism of simvastatin in rats.
Topics: Animals; Anticholesteremic Agents; Biological Transport; Catechin; Female; Food-Drug Interactions; HEK293 Cells; Humans; Organic Anion Transporters; Rats; Rats, Sprague-Dawley; Simvastatin | 2017 |
Tea polyphenols EGCG and TF restrict tongue and liver carcinogenesis simultaneously induced by N-nitrosodiethylamine in mice.
Topics: Animals; Apoptosis; beta Catenin; Biflavonoids; Body Weight; Carcinogenesis; Catechin; Cell Proliferation; Diethylnitrosamine; Female; Hedgehog Proteins; Liver Neoplasms; Mice; Polyphenols; Tongue Neoplasms; Up-Regulation; Wnt Proteins | 2016 |
Synergistic Effects of Potentilla fruticosa L. Leaves Combined with Green Tea Polyphenols in a Variety of Oxidation Systems.
Topics: Antioxidants; Benzothiazoles; Biphenyl Compounds; Camellia sinensis; Catechin; China; Chromatography, High Pressure Liquid; Dietary Supplements; Drug Synergism; Oxidation-Reduction; Phenols; Picrates; Plant Extracts; Plant Leaves; Polyphenols; Potentilla; Sulfonic Acids; Tea | 2016 |
Cholesterol induces surface localization of polyphenols in model membranes thus enhancing vesicle stability against lysozyme, but reduces protection of distant double bonds from reactive-oxygen species.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Antioxidants; Catechin; Cholesterol; Dimyristoylphosphatidylcholine; Flavanones; Fluorescence Polarization; Hydrophobic and Hydrophilic Interactions; Lignans; Linoleic Acid; Lipid Bilayers; Lipid Peroxidation; Liposomes; Muramidase; Reactive Oxygen Species; Resveratrol; Stilbenes; Surface Properties | 2016 |
Antioxidant Nanocomplexes for Delivery of Epigallocatechin-3-gallate.
Topics: Antioxidants; Catechin; Microscopy, Electron, Transmission; Nanoparticles; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared | 2016 |
The Powdering Process with a Set of Ceramic Mills for Green Tea Promoted Catechin Extraction and the ROS Inhibition Effect.
Topics: Catechin; Chromatography, High Pressure Liquid; Hot Temperature; Plant Leaves; Powders; Reactive Oxygen Species; Tandem Mass Spectrometry; Tea; Water | 2016 |
A-type dimeric epigallocatechin-3-gallate (EGCG) is a more potent inhibitor against the formation of insulin amyloid fibril than EGCG monomer.
Topics: Amyloid; Animals; Catechin; Cattle; Insulin; Protein Aggregation, Pathological | 2016 |
Neurorestorative effects of epigallocatechin-3-Gallate on cognitive function in a chronic cerebral hypoperfusion rat model.
Topics: Animals; Brain-Derived Neurotrophic Factor; Catechin; Cerebrovascular Disorders; Cognition Disorders; Disease Models, Animal; Drug Administration Routes; Escape Reaction; Hippocampus; Male; Malondialdehyde; Maze Learning; Neuroprotective Agents; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase; Vascular Endothelial Growth Factor A | 2016 |
Effects of natural antimicrobials on bacterial cell hydrophobicity, adhesion, and zeta potential.
Topics: Anti-Infective Agents; Bacillus cereus; Bacterial Adhesion; Catechin; Cinnamates; Coumaric Acids; Depsides; Food Contamination; Food Safety; Gram-Negative Bacteria; Gram-Positive Bacteria; Hydrophobic and Hydrophilic Interactions; Polystyrenes; Rosmarinic Acid | 2016 |
Epigallocatechin gallate (EGCG) inhibits adhesion and migration of neural progenitor cells in vitro.
Topics: Animals; Catechin; Cell Adhesion; Cell Movement; Cells, Cultured; Dietary Supplements; Female; Glial Fibrillary Acidic Protein; Humans; Integrin beta1; Laminin; Nestin; Neural Stem Cells; Pregnancy; Rats | 2017 |
The Natural Polyphenol Epigallocatechin Gallate Protects Intervertebral Disc Cells from Oxidative Stress.
Topics: Adult; Aged; Antioxidants; beta-Galactosidase; Catechin; Cell Death; Cell Proliferation; Cell Survival; Cellular Senescence; Cytoprotection; Enzyme Activation; Humans; Intervertebral Disc; Membrane Potential, Mitochondrial; Middle Aged; Models, Biological; Oxidative Stress; Phosphatidylinositol 3-Kinases; Protective Agents; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Reproducibility of Results; Young Adult | 2016 |
Green tea (-)-epigallocatechin gallate inhibits the growth of human villous trophoblasts via the ERK, p38, AMP-activated protein kinase, and protein kinase B pathways.
Topics: AMP-Activated Protein Kinases; Androstadienes; Bromodeoxyuridine; Catechin; Cell Proliferation; Cells, Cultured; Chromones; Humans; MAP Kinase Signaling System; Morpholines; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Tea; Trophoblasts; Wortmannin | 2016 |
Epigallocatechin-3-Gallate Attenuates the Effects of TNF-α in Vascular Endothelial Cells by Causing Ectodomain Shedding of TNF Receptor 1.
Topics: ADAM10 Protein; Blotting, Western; Calcium; Catechin; Cell Line; Cell Membrane; Egtazic Acid; Endothelial Cells; Endothelin-1; Gene Expression; Humans; Microscopy, Fluorescence; Receptors, Tumor Necrosis Factor, Type I; RNA Interference; RNA, Small Interfering; Tumor Necrosis Factor-alpha | 2016 |
Head-to-Head Comparison of Anti-Inflammatory Performance of Known Natural Products In Vitro.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Berberine; Biological Products; Blood Platelets; Caco-2 Cells; Catechin; Cell Line; Curcumin; Humans; Interleukin-6; Interleukin-8; Macrophages; Mice; Neutrophils; Platelet Activation; Pravastatin; Prednisolone; Primary Cell Culture; Reactive Oxygen Species; Stilbenes; Tumor Necrosis Factor-alpha | 2016 |
Reduction in promotor methylation utilizing EGCG (epigallocatechin-3-gallate) restores RXRα expression in human colon cancer cells.
Topics: Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Colonic Neoplasms; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; Retinoid X Receptor alpha; Tea | 2016 |
Effects of prolonged ingestion of epigallocatechin gallate on diabetes type 1-induced vascular modifications in the erectile tissue of rats.
Topics: Animals; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Male; Muscle, Smooth; Penis; Rats; Rats, Wistar; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2016 |
(-)-Epigallocatechin-3-gallate (EGCG) attenuates arsenic-induced cardiotoxicity in rats.
Topics: Animals; Antioxidants; Apoptosis; Arsenic; Calcium; Cardiotoxicity; Catechin; Heart; Male; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2016 |
Integrity of a HPV11 infection cell model and identification of (-)-Epigallocatechin-3-gallate as a potential HPV11 inhibitor.
Topics: Catechin; Cell Culture Techniques; Cell Cycle; Cell Line, Transformed; Cell Proliferation; Cell Separation; Condylomata Acuminata; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression; Host-Pathogen Interactions; Human papillomavirus 11; Humans; Interferon-alpha; Keratinocytes; Oncogene Proteins, Viral; Recombinant Proteins; RNA, Messenger; Signal Transduction; Transfection | 2016 |
(‑)‑Epigallocatechin‑3‑gallate induces apoptosis in human pancreatic cancer cells via PTEN.
Topics: Apoptosis; Catechin; Cell Proliferation; Gene Knockdown Techniques; Humans; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; RNA Interference; RNA, Small Interfering; Signal Transduction | 2016 |
[In vivo study of the renoprotective effects of EGCG in diabetic db/db mice].
Topics: Angiotensin II; Animals; Catechin; Diabetes Mellitus; Kidney; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 3; NADPH Oxidases; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Proteinuria; Proto-Oncogene Proteins c-akt | 2016 |
Synthesis and Biological Testing of Novel Glucosylated Epigallocatechin Gallate (EGCG) Derivatives.
Topics: Antioxidants; Catechin; Cell Line, Tumor; Glucose; Humans | 2016 |
Neuroprotective Activity of (-)-Epigallocatechin Gallate against Lipopolysaccharide-Mediated Cytotoxicity.
Topics: Animals; Catechin; Cell Survival; Cells, Cultured; Culture Media; Humans; Inflammation; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Leukocytes, Mononuclear; Lipopolysaccharides; Macrophage Activation; Macrophages; Neurons; Neuroprotective Agents; Rats; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Tea; Tumor Necrosis Factor-alpha | 2016 |
Epigallocatechin gallate sensitizes cisplatin-resistant oral cancer CAR cell apoptosis and autophagy through stimulating AKT/STAT3 pathway and suppressing multidrug resistance 1 signaling.
Topics: Apoptosis; Apoptosis Regulatory Proteins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Autophagy; Autophagy-Related Proteins; Caspase 3; Caspase 9; Catechin; Cell Line, Tumor; Cisplatin; Down-Regulation; Humans; Microscopy, Fluorescence; Mouth Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; STAT3 Transcription Factor | 2017 |
Delayed Treatment with Green Tea Polyphenol EGCG Promotes Neurogenesis After Ischemic Stroke in Adult Mice.
Topics: Animals; Brain Ischemia; Catechin; Cell Differentiation; Cell Movement; Cell Polarity; Cell Proliferation; Male; Mice, Inbred C57BL; Microglia; Neural Stem Cells; Neurogenesis; Neurons; Phenotype; Polyphenols; Proto-Oncogene Proteins c-akt; Recovery of Function; Signal Transduction; Stroke | 2017 |
Green tea (-)-epigallocatechin gallate induced growth inhibition of human placental choriocarcinoma cells.
Topics: AMP-Activated Protein Kinases; Antimitotic Agents; Catechin; Cell Line, Tumor; Cell Proliferation; Choriocarcinoma; Extracellular Signal-Regulated MAP Kinases; Female; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pregnancy; Tea; Uterine Neoplasms | 2016 |
Role of continuous phase protein, (-)-epigallocatechin-3-gallate and carrier oil on β-carotene degradation in oil-in-water emulsions.
Topics: beta Carotene; Catechin; Corn Oil; Dietary Supplements; Emulsions; Lactalbumin; Water | 2016 |
(-)-Epigallocatechin-3-gallate decreases colonic inflammation and permeability in a mouse model of colitis, but reduces macronutrient digestion and exacerbates weight loss.
Topics: Animals; Biomarkers; Caco-2 Cells; Catechin; Chemokine CCL2; Colitis, Ulcerative; Dextran Sulfate; Digestion; Disease Models, Animal; Humans; Intestinal Absorption; Male; Mice, Inbred Strains; Oxidative Stress; Permeability; Weight Loss | 2016 |
SphK1 inhibitor potentiates the anti-cancer effect of EGCG on leukaemia cells.
Topics: Antineoplastic Agents; Catechin; Cell Line, Tumor; Cell Survival; Drug Synergism; Enzyme Inhibitors; Gene Expression; Humans; Leukemia; Phosphotransferases (Alcohol Group Acceptor) | 2017 |
Comparative effects of selected plant polyphenols, gallic acid and epigallocatechin gallate, on matrix metalloproteinases activity in multidrug resistant MCF7/DOX breast cancer cells.
Topics: Antibiotics, Antineoplastic; Breast Neoplasms; Catechin; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Female; Gallic Acid; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; MCF-7 Cells | 2016 |
Encapsulation of biophenolic phytochemical EGCG within lipid nanoparticles enhances its stability and cytotoxicity against cancer.
Topics: Antineoplastic Agents, Phytogenic; Capsules; Catechin; Cell Line, Tumor; Drug Carriers; Drug Liberation; Drug Stability; Humans; Hydrogen-Ion Concentration; Lipids; Nanoparticles; Structure-Activity Relationship | 2016 |
Epigallocatechin gallate inhibits urate crystals-induced peritoneal inflammation in C57BL/6 mice.
Topics: Animals; Catechin; Cell Line; Chemokine CCL2; Humans; Interleukin-1beta; Interleukin-6; Male; Mice, Inbred C57BL; Monocytes; Neutrophil Infiltration; NLR Family, Pyrin Domain-Containing 3 Protein; Peritonitis; Uric Acid | 2016 |
Antimicrobial activity of tea catechin against canine oral bacteria and the functional mechanisms.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Camellia sinensis; Catechin; Dogs; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Microbiota; Mouth; Plant Leaves; Streptococcus mutans; Tea | 2016 |
Epigallocatechin gallate exerts protective effects against myocardial ischemia/reperfusion injury through the PI3K/Akt pathway-mediated inhibition of apoptosis and the restoration of the autophagic flux.
Topics: Animals; Apoptosis; Autophagy; Cardiotonic Agents; Catechin; Creatine Kinase, MB Form; Disease Models, Animal; Hemodynamics; L-Lactate Dehydrogenase; Male; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; TOR Serine-Threonine Kinases | 2016 |
Quantitative comparison of cancer and normal cell adhesion using organosilane monolayer templates: an experimental study on the anti-adhesion effect of green-tea catechins.
Topics: Catechin; Cell Adhesion; Cell Line, Tumor; Humans; Pancreas; Pancreatic Neoplasms; Tea | 2016 |
pH and temperature stability of (-)-epigallocatechin-3-gallate-β-cyclodextrin inclusion complex-loaded chitosan nanoparticles.
Topics: beta-Cyclodextrins; Catechin; Chitosan; Drug Carriers; Drug Stability; Hydrogen-Ion Concentration; Nanoparticles; Particle Size; Temperature | 2016 |
Strong Inhibition of Secretory Sphingomyelinase by Catechins, Particularly by (-)-Epicatechin 3-O-Gallate and (-)-3'-O-Methylepigallocatechin 3-O-Gallate.
Topics: Animals; Atherosclerosis; Catechin; Diabetes Mellitus, Type 2; Disease Models, Animal; Hydrogen-Ion Concentration; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sphingomyelin Phosphodiesterase | 2016 |
Effect of Tea Catechins on Folate Analysis in Green Tea by Microbiological Assay.
Topics: alpha-Amylases; Aspergillus oryzae; Catechin; Enzyme Inhibitors; Folic Acid; gamma-Glutamyl Hydrolase; Lactobacillus acidophilus; Peptide Hydrolases; Streptomyces griseus; Tea | 2016 |
Combined treatment of epigallocatechin gallate and Coenzyme Q10 attenuates cisplatin-induced nephrotoxicity via suppression of oxidative/nitrosative stress, inflammation and cellular damage.
Topics: Animals; Antineoplastic Agents; Apoptosis; Catechin; Cisplatin; Inflammation; Kidney; Male; Nitrosation; Oxidative Stress; Rats; Rats, Wistar; Ubiquinone | 2016 |
NEAT1 upregulates EGCG-induced CTR1 to enhance cisplatin sensitivity in lung cancer cells.
Topics: A549 Cells; Animals; Anticarcinogenic Agents; Carcinoma, Non-Small-Cell Lung; Catechin; Cation Transport Proteins; Cell Proliferation; Chemotherapy, Adjuvant; Cisplatin; Copper Transporter 1; Down-Regulation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Lung; Lung Neoplasms; Mice; Mice, Nude; MicroRNAs; Microscopy, Fluorescence; RNA Interference; RNA, Long Noncoding; RNA, Small Interfering; Up-Regulation; Xenograft Model Antitumor Assays | 2016 |
Correlation of In Vivo and In Vitro Assay Results for Assessment of Free Radical Scavenging Activity of Green Tea Nutraceuticals.
Topics: Animals; Antioxidants; Aspartate Aminotransferases; Camellia sinensis; Catechin; Dietary Supplements; Glutathione; In Vitro Techniques; Liver; Male; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Plant Extracts; Polyphenols; Rats, Wistar; Reactive Oxygen Species; Tea; Thiobarbituric Acid Reactive Substances | 2016 |
The behaviour of green tea catechins in a full-fat milk system under conditions mimicking the cheesemaking process.
Topics: Animals; Antioxidants; Catechin; Cheese; Chromatography, High Pressure Liquid; Dietary Fats; Food Handling; Hydrogen-Ion Concentration; Milk; Phenols; Plant Extracts; Tea; Temperature | 2016 |
In vitro and in vivo anti-diabetic and hepatoprotective effects of edible pods of Parkia roxburghii and quantification of the active constituent by HPLC-PDA.
Topics: alpha-Amylases; alpha-Glucosidases; Animals; Biomarkers; Blood Glucose; Catechin; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Fabaceae; Fruit; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Liver; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Wistar; Streptozocin; Time Factors | 2016 |
Investigation of the Effect of Different Emulsifiers on the Transdermal Delivery of EGCG Entrapped in a Polymeric Micelle System.
Topics: Administration, Cutaneous; Antioxidants; Catechin; Drug Delivery Systems; Emulsifying Agents; Humans; In Vitro Techniques; Micelles; Skin | 2017 |
Evaluation of epigallocatechin-3-gallate (EGCG) cross-linked collagen membranes and concerns on osteoblasts.
Topics: Animals; Catechin; Cell Line; Collagen; Humans; Materials Testing; Membranes, Artificial; Mice; Osteoblasts; Tissue Scaffolds; Wettability | 2016 |
Antimicrobial application of nanofibrous mats self-assembled with chitosan and epigallocatechin gallate.
Topics: Aluminum Silicates; Anti-Infective Agents; Catechin; Cellulose; Chitosan; Microbial Sensitivity Tests; Minerals; Nanofibers; Photoelectron Spectroscopy; Staphylococcus aureus; Static Electricity; Tensile Strength | 2016 |
Suppressive effect of epigallocatechin-3-O-gallate on endoglin molecular regulation in myocardial fibrosis in vitro and in vivo.
Topics: Angiotensin II; Animals; Anthracenes; Catechin; Cell Proliferation; Cells, Cultured; Endoglin; Fibrosis; Heart Failure; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Male; Models, Biological; Myocardial Infarction; Myocardium; Promoter Regions, Genetic; Protein Binding; Rats, Wistar; RNA, Small Interfering; Signal Transduction; Transcription Factor AP-1 | 2016 |
P38 MAPK/miR-1 are involved in the protective effect of EGCG in high glucose-induced Cx43 downregulation in neonatal rat cardiomyocytes.
Topics: Animals; Catechin; Cells, Cultured; Connexin 43; Down-Regulation; Gap Junctions; Glucose; MAP Kinase Signaling System; MicroRNAs; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats | 2016 |
Epigallocatechin gallate suppresses Chlamydia pneumoniae mediated IgE responses in peripheral blood mononuclear cells: a pilot study.
Topics: Adult; Antioxidants; Asthma; Catechin; Cells, Cultured; Chlamydophila pneumoniae; Female; Humans; Immunoglobulin E; Leukocytes, Mononuclear; Male; Pilot Projects; Young Adult | 2016 |
Evaluating the Reduced Hydrophobic Taste Sensor Response of Dipeptides by Theasinensin A by Using NMR and Quantum Mechanical Analyses.
Topics: Benzopyrans; Biosensing Techniques; Catechin; Diffusion; Dipeptides; Humans; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Molecular; Phenols; Protein Binding; Protons; Quantum Theory; Solutions; Taste; Thermodynamics | 2016 |
Impact of molecular weight on the formation of electrosprayed chitosan microcapsules as delivery vehicles for bioactive compounds.
Topics: Antioxidants; Antiviral Agents; Capsules; Catechin; Chitosan; Drug Carriers; Electricity; Molecular Weight; Rheology | 2016 |
Facile Separation of 5-O-Galloylquinic Acid from Chinese Green Tea Extract using Mesoporous Zirconium Phosphate.
Topics: Adsorption; Antioxidants; Catechin; Chemical Fractionation; Molecular Structure; Plant Extracts; Quinic Acid; Tea; Zirconium | 2016 |
Epigallocatechin-3-gallate protects retinal vascular endothelial cells from high glucose stress in vitro via the MAPK/ERK-VEGF pathway.
Topics: Apoptosis; Blindness; Catechin; Cell Cycle; Diabetic Retinopathy; Endothelial Cells; Flow Cytometry; Gene Expression Regulation; Glucose; Humans; Intercellular Adhesion Molecule-1; Interleukin-6; MAP Kinase Signaling System; NF-kappa B; Retina; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2016 |
Epigallocatechin Gallate (EGCG) Decorating Soybean Seed Ferritin as a Rutin Nanocarrier with Prolonged Release Property in the Gastrointestinal Tract.
Topics: Biological Availability; Catechin; Delayed-Action Preparations; Ferritins; Gastrointestinal Tract; Glycine max; Iron; Nanostructures; Polyphenols; Rutin | 2016 |
Synergistic Effect of Artificial Tears Containing Epigallocatechin Gallate and Hyaluronic Acid for the Treatment of Rabbits with Dry Eye Syndrome.
Topics: Animals; Catechin; Cytokines; Disease Models, Animal; Drug Synergism; Dry Eye Syndromes; Epithelial Cells; Epithelium, Corneal; Gene Expression Profiling; Humans; Hyaluronic Acid; Inflammation Mediators; Lubricant Eye Drops; Male; Rabbits | 2016 |
Inhibition of green tea polyphenol EGCG((-)-epigallocatechin-3-gallate) on the proliferation of gastric cancer cells by suppressing canonical wnt/β-catenin signalling pathway.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; beta Catenin; Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Humans; Male; Mice; Mice, Nude; Signal Transduction; Stomach Neoplasms; Tea; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2016 |
Potent effects of peracetylated (-)-epigallocatechin-3-gallate against hydrogen peroxide-induced damage in human epidermal melanocytes via attenuation of oxidative stress and apoptosis.
Topics: Acetates; Antioxidants; Apoptosis; Caspase 3; Caspase 9; Catechin; Cell Survival; Epidermis; Humans; Hydrogen Peroxide; Melanocytes; Membrane Potential, Mitochondrial; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Vitiligo | 2016 |
The green tea molecule EGCG inhibits Zika virus entry.
Topics: Animals; Antiviral Agents; Catechin; Cell Survival; Cells, Cultured; Chlorocebus aethiops; Dose-Response Relationship, Drug; Molecular Structure; Plant Extracts; Tea; Vero Cells; Virus Internalization; Zika Virus | 2016 |
Kinetic Study of Aroxyl-Radical-Scavenging and α-Tocopherol-Regeneration Rates of Five Catecholamines in Solution: Synergistic Effect of α-Tocopherol and Catecholamines.
Topics: alpha-Tocopherol; Catechin; Catecholamines; Free Radical Scavengers; Free Radicals; Kinetics; Oxidation-Reduction; Solutions; Spectrophotometry; Structure-Activity Relationship | 2016 |
Protective potential of epigallocatechin-3-gallate against benign prostatic hyperplasia in metabolic syndrome rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Catechin; Cytokines; Disease Models, Animal; Male; Metabolic Syndrome; Oxidative Stress; Peroxisome Proliferator-Activated Receptors; Prostatic Hyperplasia; Rats, Sprague-Dawley; Somatomedins | 2016 |
In vitro and in vivo study of epigallocatechin-3-gallate-induced apoptosis in aerobic glycolytic hepatocellular carcinoma cells involving inhibition of phosphofructokinase activity.
Topics: Aerobiosis; Apoptosis; Carcinoma, Hepatocellular; Catechin; Glycolysis; Hep G2 Cells; Humans; Liver Neoplasms; Neoplasm Proteins; Phosphofructokinases | 2016 |
Isozyme Specific Allosteric Regulation of Human Sulfotransferase 1A1.
Topics: Allosteric Regulation; Allosteric Site; Arylsulfotransferase; Catechin; Humans; Isoenzymes; Kinetics; Ligands; Phosphoadenosine Phosphosulfate; Recombinant Proteins; Substrate Specificity | 2016 |
[Characteristic Chromatograms Analysis and Simultaneous Determination of Six Marker Components in Xinnaojian Capsules].
Topics: Caffeine; Capsules; Catechin; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Gallic Acid; Quality Control | 2015 |
Epigallocatechin Gallate (EGCG) Inhibits Alpha-Synuclein Aggregation: A Potential Agent for Parkinson's Disease.
Topics: alpha-Synuclein; Catechin; Cells, Cultured; Humans; Lewy Bodies; Parkinson Disease | 2016 |
Interaction between Pin1 and its natural product inhibitor epigallocatechin-3-gallate by spectroscopy and molecular dynamics simulations.
Topics: Anticarcinogenic Agents; Antioxidants; Binding Sites; Catechin; Humans; Hydrogen Bonding; Molecular Dynamics Simulation; NIMA-Interacting Peptidylprolyl Isomerase; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Static Electricity; Thermodynamics | 2016 |
Green Tea Catechin-Based Complex Micelles Combined with Doxorubicin to Overcome Cardiotoxicity and Multidrug Resistance.
Topics: Antibiotics, Antineoplastic; Cardiotoxicity; Catechin; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Resistance, Multiple; Humans; Micelles; Nanostructures; Tea | 2016 |
The photobase generator nifedipine as a novel matrix for the detection of polyphenols in matrix-assisted laser desorption/ionization mass spectrometry.
Topics: Catechin; Dihydropyridines; Indoles; Limit of Detection; Nifedipine; Photochemical Processes; Polymerization; Polyphenols; Protons; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2016 |
Green tea catechins are potent anti-oxidants that ameliorate sodium iodate-induced retinal degeneration in rats.
Topics: Administration, Oral; Animals; Antioxidants; Catechin; Dinoprost; Gene Expression Regulation; Iodates; Ophthalmoscopy; Oxidative Stress; Rats, Sprague-Dawley; Retinal Degeneration; Retinal Pigment Epithelium; Tea | 2016 |
The Reversal Effect and Its Mechanisms of Tetramethylpyrazine on Multidrug Resistance in Human Bladder Cancer.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Catechin; Cell Cycle; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Ginsenosides; Humans; Neoplasm Proteins; Pyrazines; Urinary Bladder Neoplasms | 2016 |
The antioxidant effect of Green Tea Mega EGCG against electromagnetic radiation-induced oxidative stress in the hippocampus and striatum of rats.
Topics: Animals; Antioxidants; Catechin; Electromagnetic Radiation; Hippocampus; Male; Neostriatum; Oxidative Stress; Rats; Rats, Wistar; Tea | 2017 |
Protection of human γB-crystallin from UV-induced damage by epigallocatechin gallate: spectroscopic and docking studies.
Topics: Catechin; gamma-Crystallins; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Oxidation-Reduction; Oxidative Stress; Protein Binding; Protein Stability; Radiation-Protective Agents; Solubility; Spectrum Analysis; Ultraviolet Rays | 2016 |
The Synthesis of trans-Flavan-3-ol Gallates by Regioselective Oxidative Etherification and Their Cytotoxicity Mediated by 67 LR.
Topics: Antineoplastic Agents; Catechin; Cell Line, Tumor; Cell Survival; Cyclization; Epichlorohydrin; Epoxy Compounds; Flavonoids; Gallic Acid; Humans; Molecular Structure; Oxidation-Reduction; Phenols; Stereoisomerism; Structure-Activity Relationship | 2016 |
Epigallocatechin Gallate Reduces Slow-Twitch Muscle Fiber Formation and Mitochondrial Biosynthesis in C2C12 Cells by Repressing AMPK Activity and PGC-1α Expression.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Catechin; Cell Line; Mice; Mitochondria; Muscle Fibers, Skeletal; Muscle Fibers, Slow-Twitch; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Reactive Oxygen Species | 2016 |
Systemic Absorption of Catechins after Intraruminal or Intraduodenal Application of a Green Tea Extract in Cows.
Topics: Animals; Biological Availability; Catechin; Catheters, Indwelling; Cattle; Chromatography, High Pressure Liquid; Digestive System Fistula; Duodenum; Female; Gastrointestinal Absorption; Jugular Veins; Plant Extracts; Rumen; Tea | 2016 |
EGCG Suppresses ERK5 Activation to Reverse Tobacco Smoke-Triggered Gastric Epithelial-Mesenchymal Transition in BALB/c Mice.
Topics: Animals; Anticarcinogenic Agents; Benzodiazepinones; Biomarkers, Tumor; Carcinogenesis; Catechin; Dietary Supplements; Disease Models, Animal; Enzyme Activation; Epithelial-Mesenchymal Transition; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 7; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Random Allocation; Smoking; Stomach Neoplasms | 2016 |
Simultaneous separation and purification of (-)-epigallocatechin gallate and caffeine from tea extract by size exclusion effect on modified porous adsorption material.
Topics: Adsorption; Caffeine; Catechin; Chromatography, Gel; Chromatography, High Pressure Liquid; Kinetics; Porosity; Spectrophotometry, Ultraviolet; Tea; Thermodynamics | 2016 |
Protective effect of epigallocatechin-3-gallate (EGCG) via Nrf2 pathway against oxalate-induced epithelial mesenchymal transition (EMT) of renal tubular cells.
Topics: Animals; Catechin; Dogs; Epithelial-Mesenchymal Transition; Fibrosis; Humans; Kidney Tubules; Madin Darby Canine Kidney Cells; NF-E2-Related Factor 2; Oxalates; RNA, Small Interfering; Signal Transduction | 2016 |
Short- and long-term effects of neonatal pharmacotherapy with epigallocatechin-3-gallate on hippocampal development in the Ts65Dn mouse model of Down syndrome.
Topics: Animals; Catechin; Cognition; Disease Models, Animal; Down Syndrome; Female; Hippocampus; Male; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Neocortex; Neural Pathways; Neurogenesis; Neuroprotective Agents; Synapses; Time Factors | 2016 |
(-)-Epigallocatechin-3-O-gallate (EGCG) attenuates the hemodynamics stimulated by caffeine through decrease of catecholamines release.
Topics: Adult; Animals; Caffeine; Catechin; Catecholamines; Dose-Response Relationship, Drug; Drug Interactions; Hemodynamics; Humans; Male; Rats; Rats, Sprague-Dawley | 2016 |
The up-regulation of Myb may help mediate EGCG inhibition effect on mouse lung adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antioxidants; Catechin; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Kruppel-Like Transcription Factors; Lung; Lung Neoplasms; Mice, Inbred Strains; MicroRNAs; Proto-Oncogene Proteins c-myb; Up-Regulation | 2016 |
Opposite Structural Effects of Epigallocatechin-3-gallate and Dopamine Binding to α-Synuclein.
Topics: alpha-Synuclein; Binding Sites; Catechin; Dopamine; Molecular Structure; Nanotechnology; Spectrometry, Mass, Electrospray Ionization | 2016 |
Green tea (-)-epigallocatechin-3-gallate counteracts daytime overeating induced by high-fat diet in mice.
Topics: Animals; Antioxidants; Catechin; Diet, High-Fat; Disease Models, Animal; Feeding Behavior; Homeostasis; Hyperphagia; Hypothalamus; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Tea | 2016 |
[Epigallocatechin-3-gallate Attenuates Myocardial Reperfusion Injury in Rats Through Activation of PI3K/Akt Signaling Pathway].
Topics: Animals; Catechin; Creatine Kinase; Interleukin-6; Interleukin-8; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Tumor Necrosis Factor-alpha; Up-Regulation | 2016 |
Epigallocatechin gallate potentially abrogates fluoride induced lung oxidative stress, inflammation via Nrf2/Keap1 signaling pathway in rats: An in-vivo and in-silico study.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Catechin; Cytokines; Fluorides; Inflammation Mediators; Kelch-Like ECH-Associated Protein 1; Lung; Male; NF-E2-Related Factor 2; Oxidative Stress; Pneumonia; Rats; Rats, Wistar; Signal Transduction | 2016 |
Prevention of abdominal aortic aneurysm progression by oral administration of green tea polyphenol in a rat model.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Catechin; Collagen; Cytokines; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Elastin; Gene Expression Regulation; Inflammation Mediators; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 9; Pancreatic Elastase; Phytotherapy; Plant Extracts; Plants, Medicinal; Polyphenols; Protein-Lysine 6-Oxidase; Rats, Sprague-Dawley; Tea; Time Factors; Tropoelastin | 2017 |
Epigallocatechin-3-gallate attenuates cadmium-induced chronic renal injury and fibrosis.
Topics: Animals; Antioxidants; Blotting, Western; Cadmium; Catechin; Fibrosis; Immunoenzyme Techniques; Male; Oxidative Stress; Rats; Rats, Wistar; Renal Insufficiency, Chronic | 2016 |
Direct inhibition of matrix metalloproteinase-2 (MMP-2) by (-)-epigallocatechin-3-gallate: A possible role for the fibronectin type II repeats.
Topics: Catechin; Humans; Matrix Metalloproteinase 2; Models, Molecular; Repetitive Sequences, Amino Acid | 2016 |
A functional chitosan membrane with grafted epigallocatechin-3-gallate and lovastatin enhances periodontal tissue regeneration in dogs.
Topics: Alkaline Phosphatase; Animals; Anti-Bacterial Agents; Catechin; Cell Adhesion; Cell Proliferation; Chitosan; Delayed-Action Preparations; Dogs; Drug Carriers; Drug Liberation; Fibroblasts; Gingiva; Guided Tissue Regeneration; Humans; Lovastatin; Male; Membranes, Artificial; Tensile Strength | 2016 |
Combinatorial epigenetic mechanisms and efficacy of early breast cancer inhibition by nutritive botanicals.
Topics: Animals; Antineoplastic Agents, Phytogenic; Brassica; Breast Neoplasms; Carcinogenesis; Catechin; Cell Proliferation; Cells, Cultured; Drug Therapy, Combination; Epigenesis, Genetic; Female; Humans; Isothiocyanates; Mice; Mice, Nude; Sulfoxides; Tea | 2016 |
6-Azido-6-deoxy-l-idose as a Hetero-Bifunctional Spacer for the Synthesis of Azido-Containing Chemical Probes.
Topics: Aldehydes; Azides; Catechin; Deoxy Sugars; Glucose; Glycosylation; Hexoses; Magnetic Resonance Spectroscopy | 2016 |
Epigallocatechin-3-gallate prevents oxidative stress-induced cellular senescence in human mesenchymal stem cells via Nrf2.
Topics: Acetylation; Adult; Catechin; Cell Nucleus; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Humans; Hydrogen Peroxide; Mesenchymal Stem Cells; Models, Biological; NF-E2-Related Factor 2; Oxidative Stress; Protein Transport; Tumor Suppressor Protein p53 | 2016 |
Reduction of Hexavalent Chromium by Green Tea Polyphenols and Green Tea Nano Zero-Valent Iron (GT-nZVI).
Topics: Catechin; Chromium; Environmental Restoration and Remediation; Hydrogen-Ion Concentration; Iron; Nanoparticles; Polyphenols; Solutions; Tea; Water Pollutants, Chemical | 2017 |
The Effective Solubilization of Hydrophobic Drugs Using Epigallocatechin Gallate or Tannic Acid-Based Formulations.
Topics: Animals; Caco-2 Cells; Catechin; Dogs; Dose-Response Relationship, Drug; Drug Compounding; Human Umbilical Vein Endothelial Cells; Humans; Hydrophobic and Hydrophilic Interactions; Madin Darby Canine Kidney Cells; Solubility; Tannins | 2016 |
A Distinct Pathway for Polar Exocytosis in Plant Cell Wall Formation.
Topics: Antioxidants; Carboxylic Ester Hydrolases; Catechin; Cell Division; Cell Line; Cell Membrane; Cell Wall; Cytokinesis; Exocytosis; Green Fluorescent Proteins; Microscopy, Confocal; Microscopy, Immunoelectron; Nicotiana; Plant Proteins; Pollen; Protein Transport; Secretory Pathway; Secretory Vesicles; trans-Golgi Network | 2016 |
Metabolic Changes of Caffeine in Tea Plant (Camellia sinensis (L.) O. Kuntze) as Defense Response to Colletotrichum fructicola.
Topics: Caffeine; Camellia sinensis; Catechin; Colletotrichum; Plant Diseases; Plant Extracts; Plant Proteins | 2016 |
(-)-Epigallocatechin gallate (EGCG)-nanoethosomes as a transdermal delivery system for docetaxel to treat implanted human melanoma cell tumors in mice.
Topics: Administration, Cutaneous; Animals; Catechin; Docetaxel; Drug Carriers; Drug Stability; Female; Humans; Mice; Nanoparticles; Permeability; Skin; Taxoids; Transdermal Patch; Xenograft Model Antitumor Assays | 2016 |
Epigallocatechin-3-gallate augments therapeutic effects of mesenchymal stem cells in skin wound healing.
Topics: Animals; Antioxidants; Catechin; Cells, Cultured; Combined Modality Therapy; Inflammation Mediators; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Rats; Rats, Wistar; Treatment Outcome; Wound Healing | 2016 |
Epigallocatechin-3-gallate (EGCG) inhibits imiquimod-induced psoriasis-like inflammation of BALB/c mice.
Topics: Aminoquinolines; Animals; Antioxidants; Body Weight; Catechin; Cytokines; Imiquimod; Inflammation; Mice; Mice, Inbred BALB C; Psoriasis; Skin; Spleen | 2016 |
Activation of autophagic flux by epigallocatechin gallate mitigates TRAIL-induced tumor cell apoptosis via down-regulation of death receptors.
Topics: Anticarcinogenic Agents; Apoptosis; Autophagy; Catechin; Cell Proliferation; Colonic Neoplasms; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Receptors, Death Domain; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured | 2016 |
Simultaneous determination of eight catechins and four theaflavins in green, black and oolong tea using new HPLC-MS-MS method.
Topics: Biflavonoids; Catechin; Chromatography, High Pressure Liquid; Polyphenols; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tea | 2016 |
Differential inhibition of human erythrocyte acetylcholinesterase by polyphenols epigallocatechin-3-gallate and resveratrol. Relevance of the membrane-bound form.
Topics: Acetylcholinesterase; Catechin; Cholinesterase Inhibitors; Drug Evaluation, Preclinical; Erythrocyte Membrane; Humans; Inhibitory Concentration 50; Resveratrol; Stilbenes | 2017 |
Catechins Variously Affect Activities of Conjugation Enzymes in Proliferating and Differentiated Caco-2 Cells.
Topics: Caco-2 Cells; Catechin; Catechol O-Methyltransferase; Cell Differentiation; Cell Proliferation; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Humans; RNA, Messenger; Tea | 2016 |
Sucrose esters improve the colloidal stability of nanoethosomal suspensions of (-)-epigallocatechin gallate for enhancing the effectiveness against UVB-induced skin damage.
Topics: Animals; Catechin; Drug Evaluation, Preclinical; Mice; Mice, Hairless; Photosensitivity Disorders; Sucrose; Sunscreening Agents; Suspensions; Ultraviolet Rays | 2017 |
Conformational Ensemble of hIAPP Dimer: Insight into the Molecular Mechanism by which a Green Tea Extract inhibits hIAPP Aggregation.
Topics: Catechin; Humans; Mass Spectrometry; Molecular Dynamics Simulation; Plant Extracts; Protein Multimerization; Protein Structure, Quaternary; Protein Structure, Secondary; Receptor-Like Protein Tyrosine Phosphatases, Class 8; Tea | 2016 |
Role of STAT1 and Oxidative Stress in Gentamicin-Induced Hair Cell Death in Organ of Corti.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Catechin; Cell Death; Gentamicins; Hair Cells, Auditory; Mice; Oxidative Stress; Reactive Oxygen Species; STAT1 Transcription Factor | 2016 |
Potential for brain accessibility and analysis of stability of selected flavonoids in relation to neuroprotection in vitro.
Topics: alpha-Synuclein; Animals; Anthocyanins; Antioxidants; Apoptosis; Brain; Catechin; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Stability; Endothelial Cells; Flavonoids; Glucosides; Humans; Necrosis; Neurons; Neuroprotective Agents; Oxidative Stress; Protein Multimerization; Quercetin; Rats, Wistar; Recombinant Proteins | 2016 |
Effect of epigallocatechin-3-o-gallate and quercetin on the cryopreservation of cartilage tissue.
Topics: Animals; Cartilage; Catechin; Cryopreservation; Dose-Response Relationship, Drug; Extracellular Matrix; Phosphorylation; Quercetin; Swine | 2017 |
Human cathelicidin LL-37 enhance the antibiofilm effect of EGCG on Streptococcus mutans.
Topics: Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Biofilms; Catechin; Cathelicidins; Humans; Microbial Sensitivity Tests; Streptococcus mutans | 2016 |
Chronic infusion of epigallocatechin-3-O-gallate into the hypothalamic paraventricular nucleus attenuates hypertension and sympathoexcitation by restoring neurotransmitters and cytokines.
Topics: Animals; Antioxidants; Arterial Pressure; Catechin; Cytokines; Hypertension; Injections; Male; Neurotransmitter Agents; Norepinephrine; Oxidative Stress; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Sympathetic Nervous System | 2016 |
Tea polyphenol epigallocatechin gallate inhibits Escherichia coli by increasing endogenous oxidative stress.
Topics: Acetylcysteine; Antioxidants; Catalase; Catechin; Escherichia coli; Hydrogen Peroxide; Oxidative Stress; Polyphenols; Reactive Oxygen Species; Tea | 2017 |
Epigallocatechin-3-gallate increased the push out bond strength of an epoxy resin sealer to root dentin.
Topics: Catechin; Dental Bonding; Dental Pulp Cavity; Dentin; Edetic Acid; Epoxy Resins; Root Canal Filling Materials; Root Canal Irrigants; Root Canal Preparation; Sodium Hypochlorite | 2016 |
In vitro and in vivo inhibition of aldose reductase and advanced glycation end products by phloretin, epigallocatechin 3-gallate and [6]-gingerol.
Topics: Aldehyde Reductase; Animals; Biomarkers; Blood Glucose; Catechin; Catechols; Cell Line; Cell Survival; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Diet, High-Fat; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Alcohols; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Kidney; Kinetics; Male; Mice, Inbred C57BL; Myocardium; Phloretin; Retinal Pigment Epithelium; Time Factors | 2016 |
Y-27632 Increases Sensitivity of PANC-1 Cells to EGCG in Regulating Cell Proliferation and Migration.
Topics: Amides; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 3; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Drug Synergism; Humans; Pancreatic Neoplasms; PPAR alpha; Pyridines; RNA, Messenger | 2016 |
Epigallocatechin-3-gallate Attenuates Renal Damage by Suppressing Oxidative Stress in Diabetic db/db Mice.
Topics: Animals; Catechin; Diabetes Insipidus, Nephrogenic; Disease Models, Animal; Kidney; Mice; Mice, Inbred C57BL; Oxidative Stress | 2016 |
Functionalization of chitosan by a free radical reaction: Characterization, antioxidant and antibacterial potential.
Topics: Anti-Bacterial Agents; Antioxidants; Catechin; Chitosan; Free Radicals; Pseudomonas; Staphylococcus aureus | 2017 |
Dissecting the contribution of Staphylococcus aureus α-phenol-soluble modulins to biofilm amyloid structure.
Topics: Amino Acid Sequence; Amyloid; Amyloidogenic Proteins; Bacterial Toxins; Biofilms; Catechin; Cloning, Molecular; Escherichia coli; Gene Expression; Genetic Vectors; Hydrophobic and Hydrophilic Interactions; Protein Isoforms; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Staphylococcus aureus; Tea | 2016 |
Green Tea Polyphenol Epigallocatechin-3-gallate-Alleviated Coxsackievirus B3-induced Myocarditis Through Inhibiting Viral Replication but Not Through Inhibiting Inflammatory Responses.
Topics: Animals; Animals, Newborn; Catechin; Cells, Cultured; Coxsackievirus Infections; HeLa Cells; Humans; Inflammation Mediators; Male; Mice; Mice, Inbred BALB C; Myocarditis; Myocytes, Cardiac; Receptors, Virus; Tea; Virus Replication | 2017 |
Antiviral effect of theaflavins against caliciviruses.
Topics: Animals; Antiviral Agents; Biflavonoids; Caliciviridae; Caliciviridae Infections; Calicivirus, Feline; Catechin; Cats; Cytopathogenic Effect, Viral; Drug Evaluation, Preclinical; Flavins; Humans; Ivermectin; Mice; Norovirus; Protein Structure, Quaternary; Sapovirus; Structure-Activity Relationship | 2017 |
Anti-cancer effect of (-)-epigallocatechin-3-gallate (EGCG) in head and neck cancer through repression of transactivation and enhanced degradation of β-catenin.
Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; beta Catenin; Catechin; Cell Line, Tumor; Cell Proliferation; Female; Gene Knockdown Techniques; Genes, p53; Head and Neck Neoplasms; Humans; Male; Mice; Mice, Inbred C3H; Middle Aged; Neoplasm Transplantation; Signal Transduction; Transcriptional Activation; Ubiquitin-Specific Proteases | 2016 |
Anti-stress effects of drinking green tea with lowered caffeine and enriched theanine, epigallocatechin and arginine on psychosocial stress induced adrenal hypertrophy in mice.
Topics: Adrenal Glands; Animals; Arginine; Caffeine; Camellia sinensis; Catechin; Drug Interactions; Glutamates; Hypertrophy; Male; Mice; Phytotherapy; Plant Extracts; Stress, Psychological; Tea; Temperature; Water | 2016 |
Epigallocatechin-3-gallate attenuates microcystin-LR induced oxidative stress and inflammation in human umbilical vein endothelial cells.
Topics: Anti-Inflammatory Agents; Antioxidants; Catechin; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Interleukin-6; Marine Toxins; Microcystins; NF-kappa B p50 Subunit; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 2017 |
Competitive binding of (-)-epigallocatechin-3-gallate and 5-fluorouracil to human serum albumin: A fluorescence and circular dichroism study.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Binding Sites; Binding, Competitive; Catechin; Circular Dichroism; Drug Synergism; Fluorouracil; Humans; Ibuprofen; Protein Structure, Secondary; Serum Albumin, Human; Spectrometry, Fluorescence; Thermodynamics; Warfarin | 2017 |
Insights on the involvement of (-)-epigallocatechin gallate in ER stress-mediated apoptosis in age-related macular degeneration.
Topics: Animals; Antioxidants; Apoptosis; Calcium; Calcium Signaling; Catechin; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Humans; Hydrogen Peroxide; Macular Degeneration; Mice; Mitochondria; Oxidative Stress; Reactive Oxygen Species; Thapsigargin; Unfolded Protein Response | 2017 |
Effective synthesis of theaflavin-3,3'-digallate with epigallocatechin-3-O-gallate and epicatechin gallate as substrates by using immobilized pear polyphenol oxidase.
Topics: Biflavonoids; Biocatalysis; Catechin; Catechol Oxidase; Cross-Linking Reagents; Enzymes, Immobilized; Equipment Reuse; Ferrosoferric Oxide; Glutaral; Kinetics; Metal Nanoparticles; Plant Proteins; Protein Multimerization; Pyrus; Substrate Specificity | 2017 |
Epigallocatechin Gallate Remodels Overexpressed Functional Amyloids in Pseudomonas aeruginosa and Increases Biofilm Susceptibility to Antibiotic Treatment.
Topics: Amyloid; Bacterial Proteins; Benzothiazoles; Biofilms; Catechin; Drug Resistance, Bacterial; Gene Expression Regulation, Bacterial; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Thiazoles; Tobramycin | 2016 |
Epigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity.
Topics: Animals; Antineoplastic Agents, Phytogenic; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; MAP Kinase Kinase Kinases; Melanoma; Mice, Inbred BALB C; Molecular Docking Simulation; Neoplasm Invasiveness; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Binding; Protein Conformation; Signal Transduction; Skin Neoplasms; Structure-Activity Relationship; TNF Receptor-Associated Factor 6; Transfection; Tumor Burden; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Ubiquitination | 2016 |
Hyaluronic Acid/PLGA Core/Shell Fiber Matrices Loaded with EGCG Beneficial to Diabetic Wound Healing.
Topics: Animals; Catechin; Collagen; Diabetes Mellitus, Experimental; Fibroblasts; Hyaluronic Acid; Neovascularization, Physiologic; Polyglycolic Acid; Rats; Rats, Sprague-Dawley; Skin; Wound Healing | 2016 |
Epigallocatechin-3-gallate protects against hepatic ischaemia-reperfusion injury by reducing oxidative stress and apoptotic cell death.
Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Catechin; Cytochromes c; Disease Models, Animal; Glutathione; Glutathione Disulfide; Inflammation; Injections, Intraperitoneal; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reperfusion Injury | 2016 |
Differentiated Caco-2 cell monolayers exhibit adaptation in the transport and metabolism of flavan-3-ols with chronic exposure to both isolated flavan-3-ols and enriched extracts.
Topics: Biological Transport; Caco-2 Cells; Catechin; Catechol O-Methyltransferase; Cell Differentiation; Flavonoids; Humans; Intestinal Mucosa; Intestines; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins | 2017 |
The Oxidative Activity of Ellagitannins Dictates Their Tendency To Form Highly Stabilized Complexes with Bovine Serum Albumin at Increased pH.
Topics: Antioxidants; Catechin; Hydrogen-Ion Concentration; Hydrolyzable Tannins; Molecular Weight; Oxidation-Reduction; Polyphenols; Protein Conformation; Serum Albumin, Bovine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2016 |
Epigallocatechin-3-gallate enhances key enzymatic activities of hepatic thioredoxin and glutathione systems in selenium-optimal mice but activates hepatic Nrf2 responses in selenium-deficient mice.
Topics: Animals; Antioxidants; Catechin; Gene Expression Regulation; Glutaredoxins; Glutathione; Glutathione Reductase; Mice; NF-E2-Related Factor 2; Reactive Oxygen Species; Selenium; Signal Transduction; Thioredoxin-Disulfide Reductase; Thioredoxins | 2016 |
Combinatorial Treatment Effects in a Cell Culture Model of Alzheimer's Disease.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antipsychotic Agents; Catechin; Cell Line, Tumor; Cytokines; Drug Combinations; Gene Expression Regulation, Neoplastic; Humans; Melatonin; Mice; Mutation; Neuroblastoma; Peptide Fragments; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Resveratrol; Stilbenes; Transfection | 2017 |
Regulation of matrix metalloproteinase secretion by green tea catechins in a three-dimensional co-culture model of macrophages and gingival fibroblasts.
Topics: Aggregatibacter actinomycetemcomitans; Catechin; Cell Line; Cell Survival; Coculture Techniques; Collagen Type I; Fibroblasts; Humans; Lipopolysaccharides; Macrophages; Matrix Metalloproteinase 3; Matrix Metalloproteinase 8; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Periodontitis; Plant Extracts; Tea; U937 Cells | 2017 |
Design, development, and characterization of lipid nanocarriers-based epigallocatechin gallate delivery system for preventive and therapeutic supplementation.
Topics: Administration, Oral; Catechin; Chemistry, Pharmaceutical; Drug Carriers; Drug Delivery Systems; Lipids; Nanoparticles; Tea | 2016 |
Inhibition of Cholera Toxin and Other AB Toxins by Polyphenolic Compounds.
Topics: ADP Ribose Transferases; Animals; Bacterial Toxins; Biflavonoids; Binding Sites; Catechin; Cell Membrane; Cells, Cultured; Chlorocebus aethiops; CHO Cells; Cholera Toxin; Cricetulus; Diphtheria Toxin; Exotoxins; Fruit; Grape Seed Extract; Molecular Docking Simulation; Phenols; Plant Extracts; Proanthocyanidins; Pseudomonas aeruginosa Exotoxin A; Ricin; Vero Cells; Virulence Factors; Vitis | 2016 |
FBS or BSA Inhibits EGCG Induced Cell Death through Covalent Binding and the Reduction of Intracellular ROS Production.
Topics: Animals; Catechin; Cattle; Cell Death; Hep G2 Cells; Humans; Intracellular Space; Molecular Docking Simulation; Protein Binding; Reactive Oxygen Species; Serum; Serum Albumin, Bovine | 2016 |
Inhibition of EMMPRIN and MMP-9 Expression by Epigallocatechin-3-Gallate through 67-kDa Laminin Receptor in PMA-Induced Macrophages.
Topics: Basigin; Catechin; Cell Death; Cell Differentiation; Cell Line; Humans; Macrophages; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Protein Kinase Inhibitors; Receptors, Laminin; Tetradecanoylphorbol Acetate | 2016 |
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Neoplastic Stem Cells; Wnt Signaling Pathway | 2017 |
Acute vascular and metabolic actions of the green tea polyphenol epigallocatechin 3-gallate in rat skeletal muscle.
Topics: Animals; Catechin; Dose-Response Relationship, Drug; Glucose; Hindlimb; Insulin; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Organ Culture Techniques; Perfusion; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Serotonin; Vasodilation | 2017 |
Green tea polyphenol "epigallocatechin-3-gallate", differentially induces apoptosis in CLL B-and T-Cells but not in healthy B-and T-Cells in a dose dependant manner.
Topics: Apoptosis; B-Lymphocytes; Catechin; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Feeder Cells; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, T-Cell; T-Lymphocytes; Tumor Cells, Cultured | 2016 |
Variation of theanine, phenolic, and methylxanthine compounds in 21 cultivars of Camellia sinensis harvested in different seasons.
Topics: Camellia sinensis; Catechin; China; Flavonoids; Glutamates; Phenols; Plant Extracts; Plant Leaves; Seasons; Xanthines | 2017 |
Epigallocatechin-3-gallate prevents cardiac apoptosis by modulating the intrinsic apoptotic pathway in isoproterenol-induced myocardial infarction.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Body Weight; Catechin; Cytoprotection; Isoproterenol; Lipid Peroxidation; Male; Myocardial Infarction; Myocardium; Organ Size; Rats; Rats, Wistar | 2017 |
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Catechin; Channelopathies; Computer Simulation; Flavonoids; Guinea Pigs; Heart; Heart Atria; Heart Ventricles; Humans; Ions; Models, Cardiovascular; Muscle Cells; Mutation; Myocardium; Phenotype; Purkinje Cells; Tea | 2016 |
Epigallocatechin Gallate Attenuates β-Amyloid Generation and Oxidative Stress Involvement of PPARγ in N2a/APP695 Cells.
Topics: Amyloid beta-Peptides; Anilides; Animals; Catechin; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Mice; Oxidative Stress; Peptide Fragments; PPAR gamma | 2017 |
Epigallocatechin-3-gallate alleviates paraquat-induced acute lung injury and inhibits upregulation of toll-like receptors.
Topics: A549 Cells; Acute Lung Injury; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Catechin; Enzyme-Linked Immunosorbent Assay; Gene Expression Profiling; Humans; Interleukin-1beta; Interleukin-6; Lung; Male; Mice; Oxidative Stress; Paraquat; Signal Transduction; Toll-Like Receptor 4; Toll-Like Receptors; Tumor Necrosis Factor-alpha; Up-Regulation | 2017 |
Txn1, Ctsd and Cdk4 are key proteins of combination therapy with taurine, epigallocatechin gallate and genistein against liver fibrosis in rats.
Topics: Animals; Anticarcinogenic Agents; Carbon Tetrachloride Poisoning; Catechin; Cathepsin D; Cyclin-Dependent Kinase 4; Drug Therapy, Combination; Genistein; Liver Cirrhosis; Male; Rats; Rats, Sprague-Dawley; Taurine; Thioredoxins; Transcriptome | 2017 |
(-)-Epigallocatechin-3-Gallate Antihyperalgesic Effect Associates With Reduced CX3CL1 Chemokine Expression in Spinal Cord.
Topics: Animals; Catechin; Chemokine CX3CL1; Female; Hyperalgesia; Mice; Mice, Inbred BALB C; Spinal Cord | 2017 |
Recovery of Chicken Growth Plate by Heat-Shock Protein 90 Inhibitors Epigallocatechin-3-Gallate and Apigenin in Thiram-Induced Tibial Dyschondroplasia.
Topics: Animals; Apigenin; Catechin; Chickens; Growth Plate; HSP90 Heat-Shock Proteins; Male; Osteochondrodysplasias; Poultry Diseases; Thiram | 2016 |
Anti‑proliferative activity of epigallocatechin‑3‑gallate and silibinin on soft tissue sarcoma cells.
Topics: Antineoplastic Agents; Antioxidants; Catechin; Cell Line, Tumor; Cell Proliferation; Fibrosarcoma; Humans; Liposarcoma; Sarcoma; Sarcoma, Synovial; Silybin; Silymarin | 2017 |
The structure of the catechin-binding site of human sulfotransferase 1A1.
Topics: Allosteric Site; Arylsulfotransferase; Catechin; Humans; Isoenzymes; Kinetics; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Recombinant Proteins; Spin Labels; Substrate Specificity | 2016 |
Surface rearrangement of adsorbed EGCG-mucin complexes on hydrophilic surfaces.
Topics: Adsorption; Catechin; Gastric Mucins; Hydrophobic and Hydrophilic Interactions; Surface Properties | 2017 |
Effect of epigallocatechin-3-gallate on acrylamide-induced oxidative stress and apoptosis in PC12 cells.
Topics: Acetylcholinesterase; Acrylamide; Animals; Apoptosis; Calcium; Caspase 3; Catechin; Cell Survival; Cytochromes c; Lipid Peroxidation; Membrane Potential, Mitochondrial; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species | 2017 |
Niosomes Consisting of Tween-60 and Cholesterol Improve the Chemical Stability and Antioxidant Activity of (-)-Epigallocatechin Gallate under Intestinal Tract Conditions.
Topics: Antioxidants; Biological Availability; Catechin; Cholesterol; Digestion; Drug Carriers; Drug Stability; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Liposomes; Nanoparticles; Pancreatin; Particle Size; Polysorbates | 2016 |
Functional Properties of Novel Epigallocatechin Gallate Glucosides Synthesized by Using Dextransucrase from Leuconostoc mesenteroides B-1299CB4.
Topics: alpha-Glucosidases; Antioxidants; Camellia sinensis; Catechin; Glucosides; Glucosyltransferases; Glycoside Hydrolase Inhibitors; Humans; Leuconostoc mesenteroides; Molecular Structure; Monophenol Monooxygenase | 2016 |
Epigallocatechin-3-Gallate Upregulates miR-221 to Inhibit Osteopontin-Dependent Hepatic Fibrosis.
Topics: Animals; Antioxidants; Catechin; Cell Line; Hep G2 Cells; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Male; MicroRNAs; Osteopontin; Rats, Sprague-Dawley; Tea; Up-Regulation | 2016 |
Epigallocatechin-3-gallate inhibits adipogenesis through down-regulation of PPARγ and FAS expression mediated by PI3K-AKT signaling in 3T3-L1 cells.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Catechin; Cell Survival; Down-Regulation; Fatty Acid Synthases; Insulin Receptor Substrate Proteins; Mice; Phosphatidylinositol 3-Kinases; PPAR gamma; Proto-Oncogene Proteins c-akt; Signal Transduction | 2017 |
(-)-Epigallocatechin-3-gallate alleviates doxorubicin-induced cardiotoxicity in sarcoma 180 tumor-bearing mice.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Calcium; Cardiotonic Agents; Cardiotoxicity; Catechin; Doxorubicin; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Mice; Microscopy, Electron, Transmission; Myocytes, Cardiac; Reactive Oxygen Species; Sarcoma 180; Superoxide Dismutase; Tea | 2017 |
Antiadipogenic Effects and Mechanisms of Combinations of Genistein, Epigallocatechin-3-Gallate, and/or Resveratrol in Preadipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Catechin; CCAAT-Enhancer-Binding Protein-alpha; Fats; Genistein; Humans; Mice; PPAR gamma; Resveratrol; Stilbenes | 2017 |
Effect of metal ions on the binding reaction of (-)-epigallocatechin gallate to β-lactoglobulin.
Topics: Catechin; Ions; Lactoglobulins; Metals; Protein Structure, Secondary | 2017 |
Solid- and solution-state nuclear magnetic resonance spectroscopic studies on antibody light chain amyloid formation and interactions with epigallocatechin gallate.
Topics: Amyloid; Animals; Catechin; Humans; Immunoglobulin Light Chains; Magnetic Resonance Spectroscopy; Mice | 2017 |
Aggregation of Full-length Immunoglobulin Light Chains from Systemic Light Chain Amyloidosis (AL) Patients Is Remodeled by Epigallocatechin-3-gallate.
Topics: Amyloid; Amyloidosis; Catechin; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Humans; Immunoglobulin Light Chains; Kinetics; Spectrometry, Fluorescence; Thermodynamics | 2017 |
Oxidized epigallocatechin gallate inhibited lysozyme fibrillation more strongly than the native form.
Topics: Amyloidogenic Proteins; Animals; Antioxidants; Ascorbic Acid; Catechin; Chickens; Half-Life; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Muramidase; Oxidation-Reduction; Solutions | 2017 |
EGCG inhibited bladder cancer SW780 cell proliferation and migration both in vitro and in vivo via down-regulation of NF-κB and MMP-9.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Catechin; Cell Line, Tumor; Dose-Response Relationship, Drug; Down-Regulation; Female; Humans; Injections, Intraperitoneal; Matrix Metalloproteinase 9; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Proteins; NF-kappa B; Random Allocation; Specific Pathogen-Free Organisms; Tumor Burden; Urinary Bladder; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays | 2017 |
Green tea epigallocatechin 3-gallate alleviates hyperglycemia and reduces advanced glycation end products via nrf2 pathway in mice with high fat diet-induced obesity.
Topics: Animals; Catechin; Diet, High-Fat; Glycation End Products, Advanced; Hyperglycemia; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Obesity; Random Allocation; Signal Transduction; Tea | 2017 |
Epigallocatechin-3-gallate promotes angiogenesis via up-regulation of Nfr2 signaling pathway in a mouse model of ischemic stroke.
Topics: Angiogenesis Inducing Agents; Animals; Brain; Catechin; Disease Models, Animal; Flavonoids; Infarction, Middle Cerebral Artery; Male; Mice, Inbred C57BL; Neovascularization, Physiologic; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Protein Kinase Inhibitors; Random Allocation; Signal Transduction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2017 |
Site-Specific Fluorescence Polarization for Studying the Disaggregation of α-Synuclein Fibrils by Small Molecules.
Topics: alpha-Synuclein; Amino Acid Sequence; Catechin; Dopamine; Fluorescence Polarization; Fluorescent Dyes; Humans; Masoprocol; Phosphatidylcholines; Protein Aggregates; Recombinant Proteins; Small Molecule Libraries; Sodium Dodecyl Sulfate; Unilamellar Liposomes; Xanthenes | 2017 |
Epigallocatechin-3-gallate Modulates MicroRNA Expression Profiles in Human Nasopharyngeal Carcinoma CNE2 Cells.
Topics: Antineoplastic Agents; Carcinoma; Catechin; Cell Line, Tumor; Computational Biology; Gene Expression; Humans; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Real-Time Polymerase Chain Reaction; Signal Transduction | 2017 |
Epigallocatechin-3-gallate attenuates acrylamide-induced apoptosis and astrogliosis in rat cerebral cortex.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acrylamide; Animals; Apoptosis; Astrocytes; Catechin; Cerebral Cortex; Deoxyguanosine; DNA Damage; Dose-Response Relationship, Drug; Glial Fibrillary Acidic Protein; Gliosis; Lipid Peroxidation; Male; Neuroprotective Agents; Oxidative Stress; Rats, Sprague-Dawley | 2017 |
Epigallocatechin-3-gallate (EGCG) and green tea polyphenols do not improve stallion semen parameters during cooling at 4°C.
Topics: Animals; Catechin; Cold Temperature; Horses; Male; Polyphenols; Semen Preservation; Tea | 2017 |
Metabolic interactions between cysteamine and epigallocatechin gallate.
Topics: Acetylation; Catechin; Cell Line; Citric Acid Cycle; Cross-Linking Reagents; Cysteamine; Cytoplasm; Epithelial Cells; Humans; Metabolic Flux Analysis; Metabolomics; Respiratory Mucosa | 2017 |
Better Management of Alcohol Liver Disease Using a 'Microstructured Synbox' System Comprising L. plantarum and EGCG.
Topics: Animals; Antioxidants; Catechin; Drug Combinations; Drug Compounding; Drug Synergism; Ethanol; Female; Lactobacillus plantarum; Liver Diseases, Alcoholic; Permeability; Prebiotics; Probiotics; Rats; Rats, Wistar | 2017 |
Extraction of Epigallocatechin Gallate and Epicatechin Gallate from Tea Leaves Using β-Cyclodextrin.
Topics: beta-Cyclodextrins; Camellia sinensis; Catechin; Chemical Fractionation; Chromatography, High Pressure Liquid; Molecular Docking Simulation; Phenols; Plant Extracts; Plant Leaves | 2017 |
Effects of Epigallocatechin Gallate on Tert-Butyl Hydroperoxide-Induced Mitochondrial Dysfunction in Rat Liver Mitochondria and Hepatocytes.
Topics: Animals; Calcium; Catechin; Cells, Cultured; Hepatocytes; Hydrogen Peroxide; Male; Membrane Potential, Mitochondrial; Mitochondria, Liver; Oxygen Consumption; Rats; Rats, Wistar; tert-Butylhydroperoxide | 2016 |
Influence of Aluminium and EGCG on Fibrillation and Aggregation of Human Islet Amyloid Polypeptide.
Topics: Aluminum; Amyloid; Catechin; Chelating Agents; Diabetes Mellitus, Type 2; Humans; Islet Amyloid Polypeptide; Kinetics; Light; Magnetic Resonance Spectroscopy; Microscopy, Electron, Transmission; Scattering, Radiation; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet | 2016 |
Oligomer formation of a tea polyphenol, EGCG, on its sensing molecule 67 kDa laminin receptor.
Topics: Antineoplastic Agents; Antioxidants; Catechin; Cell Death; Cell Proliferation; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Molecular Structure; Peptides; Receptors, Laminin; Surface Plasmon Resonance; Tea; Thermodynamics | 2017 |
Nephro-toxic effects of intraperitoneally injected EGCG in diabetic mice: involvement of oxidative stress, inflammation and apoptosis.
Topics: Animals; Apoptosis; Biomarkers; Blood Urea Nitrogen; Body Weight; Caspase 3; Catechin; Cystatin C; Diabetes Mellitus, Experimental; Inflammation; Injections, Intraperitoneal; Kidney; Lipocalin-2; Male; Mice; Oxidative Stress | 2017 |
Cytokines, inducers and inhibitors modulate MMP-2 and MMP‑9 secretion by human Fanconi anemia immortalized fibroblasts.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antioxidants; Carcinogens; Catechin; Cattle; Cells, Cultured; Cytokines; Doxycycline; Enzyme Activators; Fanconi Anemia; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Interleukin-1beta; Lipopolysaccharides; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Necrosis Factor-alpha | 2017 |
Inactivation of Soybean Trypsin Inhibitor by Epigallocatechin Gallate: Stopped-Flow/Fluorescence, Thermodynamics, and Docking Studies.
Topics: Amino Acid Motifs; Animals; Catechin; Fluorescence; Glycine max; Kinetics; Milk; Molecular Docking Simulation; Soy Milk; Thermodynamics; Trypsin Inhibitor, Kunitz Soybean | 2017 |
A new update for radiocontrast-induced nephropathy aggravated with glycerol in rats: the protective potential of epigallocatechin-3-gallate.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; Catechin; Contrast Media; Cytokines; Glycerol; Kidney; Kidney Diseases; Male; Oxidative Stress; Rats; Rats, Wistar; Tea | 2017 |
The Peroxidation of Leukocytes Index Ratio Reveals the Prooxidant Effect of Green Tea Extract.
Topics: Adult; Antioxidants; Catechin; Chromans; Dietary Supplements; Female; Humans; Leukocytes; Lipid Peroxidation; Male; Plant Extracts; Tea; Tetradecanoylphorbol Acetate; Uric Acid; Young Adult | 2016 |
The Green Tea Catechin Epigallocatechin Gallate Ameliorates Graft-versus-Host Disease.
Topics: Alkaloids; Allografts; Animals; Antioxidants; Benzodioxoles; Catechin; Disease Models, Animal; Female; Graft Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunologic Factors; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neovascularization, Pathologic; Oxidative Stress; Piperidines; Polyunsaturated Alkamides; Quercetin; T-Lymphocytes, Regulatory; Tea | 2017 |
EGCG, a tea polyphenol, as a potential mitigator of hematopoietic radiation injury in mice.
Topics: Animals; Bone Marrow Cells; Catechin; Cell Cycle; Deoxyribonucleases; Hematopoietic System; Histone Deacetylase Inhibitors; Male; Mice; Mice, Inbred C57BL; Micronucleus Tests; Radiation Injuries, Experimental; Radiation-Protective Agents; Survival Analysis; Whole-Body Irradiation | 2017 |
Epigallocatechin-3-O-gallate modulates global microRNA expression in interleukin-1β-stimulated human osteoarthritis chondrocytes: potential role of EGCG on negative co-regulation of microRNA-140-3p and ADAMTS5.
Topics: 3' Untranslated Regions; ADAMTS5 Protein; Anti-Inflammatory Agents, Non-Steroidal; Base Sequence; Cartilage, Articular; Catechin; Cells, Cultured; Chondrocytes; Computational Biology; Conserved Sequence; Dietary Supplements; Gene Expression Profiling; Gene Expression Regulation; Humans; Interleukin-1beta; MicroRNAs; Oligonucleotide Array Sequence Analysis; Osteoarthritis, Knee; RNA Interference | 2018 |
Modulation of MMP-2 and MMP-9 secretion by cytokines, inducers and inhibitors in human glioblastoma T-98G cells.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antioxidants; Carcinogens; Catechin; Cattle; Cytokines; Doxycycline; Enzyme Activators; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Interleukin-1beta; Lipopolysaccharides; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2017 |
Epigallocatechin gallate induces a hepatospecific decrease in the CYP3A expression level by altering intestinal flora.
Topics: Animals; Catechin; Cell Line, Tumor; Clostridium; Cytochrome P-450 CYP3A; Feces; Gastrointestinal Microbiome; Humans; Intestines; Lithocholic Acid; Liver; Male; Mice, Inbred ICR; RNA, Ribosomal, 16S | 2017 |
Preparation of arginine-glycine-aspartic acid-modified biopolymeric nanoparticles containing epigalloccatechin-3-gallate for targeting vascular endothelial cells to inhibit corneal neovascularization.
Topics: Angiogenesis Inhibitors; Animals; Burns, Chemical; Catechin; Cell Survival; Corneal Neovascularization; Disease Models, Animal; Eye Burns; Human Umbilical Vein Endothelial Cells; Humans; Hyaluronic Acid; Integrin alphaVbeta3; Mice, Inbred C57BL; Molecular Targeted Therapy; Nanoparticles; Oligopeptides; Ophthalmic Solutions | 2017 |
Epigallocatechin-3-gallate modulates arrhythmogenic activity and calcium homeostasis of left atrium.
Topics: Action Potentials; Animals; Atrial Fibrillation; Atrial Function, Left; Calcium; Catechin; Cells, Cultured; Heart Atria; Homeostasis; Male; Myocytes, Cardiac; Rabbits | 2017 |
Skin Delivery of EGCG and Silibinin: Potential of Peptide Dendrimers for Enhanced Skin Permeation and Deposition.
Topics: Administration, Cutaneous; Animals; Antioxidants; Catechin; Dendrimers; Male; Peptides; Permeability; Rats; Rats, Wistar; Silybin; Silymarin; Skin Absorption | 2017 |
Epigallocatechin-3-gallate preferentially induces aggregation of amyloidogenic immunoglobulin light chains.
Topics: Amino Acid Sequence; Amyloid; Binding Sites; Catechin; Chemical Precipitation; Humans; Immunoglobulin Light Chains; Kinetics; Magnetic Resonance Spectroscopy; Mutation; Proline; Protein Aggregates; Sequence Alignment | 2017 |
Involvement of PKCα and ERK1/2 signaling pathways in EGCG's protection against stress-induced neural injuries in Wistar rats.
Topics: Adenosine Triphosphate; Animals; Catechin; Dopamine; Hippocampus; Hydrocortisone; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neocortex; Neurons; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Protein Kinase C-alpha; Rats; Rats, Wistar; RNA, Messenger; Serotonin; Signal Transduction; Stress, Psychological | 2017 |
Effects of Epigallocatechin Gallate, an Antibacterial Cross-linking Agent, on Proliferation and Differentiation of Human Dental Pulp Cells Cultured in Collagen Scaffolds.
Topics: Alkaline Phosphatase; Anti-Bacterial Agents; Catechin; Cell Differentiation; Cell Proliferation; Cells, Cultured; Collagen; Cross-Linking Reagents; Dental Pulp; Gene Expression Profiling; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Real-Time Polymerase Chain Reaction; Tissue Scaffolds | 2017 |
Targeted nanoparticles encapsulating (-)-epigallocatechin-3-gallate for prostate cancer prevention and therapy.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Liberation; Humans; Kinetics; Ligands; Male; Mice; Molecular Conformation; Molecular Targeted Therapy; Nanoparticles; Particle Size; Polyesters; Polyethylene Glycols; Prostatic Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays | 2017 |
Green Tea Polyphenol Epigallocatechin-3-gallate Suppresses Toll-like Receptor 4 Expression via Up-regulation of E3 Ubiquitin-protein Ligase RNF216.
Topics: Animals; Catechin; Cells, Cultured; Gene Expression Regulation; Hyperinsulinism; Hypertriglyceridemia; Inflammation; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Obesity; Receptors, Laminin; Signal Transduction; Tea; Toll-Like Receptor 4; Transcriptional Activation; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases; Up-Regulation | 2017 |
Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage.
Topics: Administration, Cutaneous; Animals; Antioxidants; Calorimetry, Differential Scanning; Catechin; Cell Line; Cell Survival; Drug Carriers; Drug Compounding; Drug Synergism; Humans; Hyaluronic Acid; Keratinocytes; Lipid Peroxidation; Male; Matrix Metalloproteinases; Nanomedicine; Nanoparticles; Oxidative Stress; Particle Size; Permeability; Phosphatidylcholines; Rats, Wistar; Reactive Oxygen Species; Skin; Skin Absorption; Skin Aging; Sodium Cholate; Spectroscopy, Fourier Transform Infrared; Surface Properties; Technology, Pharmaceutical; Time Factors; X-Ray Diffraction | 2017 |
Evaluation of plasma antioxidant activity in rats given excess EGCg with reference to endogenous antioxidants concentrations and assay methods.
Topics: Animals; Antioxidants; Ascorbic Acid; Blood Chemical Analysis; Catechin; Lymphocytes; Male; Oxidation-Reduction; Plasma; Rats; Rats, Wistar | 2017 |
Resveratrol and Epigallocatechin-3-gallate addition to thawed boar sperm improves in vitro fertilization.
Topics: Acrosome; Animals; Antioxidants; Catechin; Cryopreservation; Dose-Response Relationship, Drug; Female; Fertilization in Vitro; Male; Resveratrol; Semen Preservation; Sperm Motility; Sperm-Ovum Interactions; Spermatozoa; Stilbenes; Sus scrofa | 2017 |
Influence of prenatal EGCG treatment and Dyrk1a dosage reduction on craniofacial features associated with Down syndrome.
Topics: Animals; Catechin; Craniofacial Abnormalities; Disease Models, Animal; Down Syndrome; Dyrk Kinases; Female; Gene Dosage; Mice; Phenotype; Phosphorylation; Pregnancy; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases | 2016 |
Dose-dependent decrease in mortality with no cognitive or muscle function improvements due to dietary EGCG supplementation in aged mice.
Topics: Aging; Animal Feed; Animals; Catechin; Diet; Dietary Supplements; Male; Mice; Mortality; Random Allocation; Social Behavior | 2017 |
Epigallocatechin gallate induces an up-regulation of LDL receptor accompanied by a reduction of PCSK9 via the annexin A2-independent pathway in HepG2 cells.
Topics: Annexin A2; Catechin; Gene Expression Regulation; Gene Knockdown Techniques; Hep G2 Cells; Humans; Lipoproteins, LDL; Lovastatin; MAP Kinase Signaling System; Proprotein Convertase 9; Receptors, LDL; Up-Regulation | 2017 |
A novel ECG analog 4-(S)-(2,4,6-trimethylthiobenzyl)-epigallocatechin gallate selectively induces apoptosis of B16-F10 melanoma via activation of autophagy and ROS.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Catechin; Cell Line; Cell Line, Tumor; Endoplasmic Reticulum Stress; Gene Expression Regulation, Neoplastic; Hepatocytes; Injections, Subcutaneous; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Proteins; Plant Extracts; Plant Roots; Reactive Oxygen Species; Rhodiola; Signal Transduction; Tumor Burden | 2017 |
Green tea polyphenol tailors cell adhesivity of RGD displaying surfaces: multicomponent models monitored optically.
Topics: Adsorption; Biosensing Techniques; Catechin; Cell Adhesion; Coated Materials, Biocompatible; Dimerization; HeLa Cells; Humans; Hydrogen Bonding; Kinetics; Models, Biological; Models, Molecular; Oligopeptides; Oxidation-Reduction; Polymers; Polyphenols; Spectrum Analysis; Surface Properties; Tea | 2017 |
Monitoring the Interactions of a Ternary Complex Using NMR Spectroscopy: The Case of Sugars, Polyphenols, and Proteins.
Topics: Catechin; Dynamic Light Scattering; Glucose; Humans; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Peptides; Polyphenols; Protein Binding; Salivary Proteins and Peptides; Sugars; Wine | 2016 |
Biofilm formation of the black yeast-like fungus Exophiala dermatitidis and its susceptibility to antiinfective agents.
Topics: Antifungal Agents; Bacterial Adhesion; beta-Glucans; Biofilms; Catechin; Colistin; Cystic Fibrosis; Echinocandins; Exophiala; Farnesol; Humans; Lipopeptides; Micafungin; Microbial Sensitivity Tests; Mycoses; Voriconazole | 2017 |
Molecular recognition between pancreatic lipase and natural and synthetic inhibitors.
Topics: Catechin; Enzyme Inhibitors; Humans; Kinetics; Lactones; Ligands; Lipase; Molecular Dynamics Simulation; Obesity; Orlistat; Pancreas | 2017 |
Substitution at the C-3 Position of Catechins Has an Influence on the Binding Affinities against Serum Albumin.
Topics: Animals; Catechin; Cattle; Humans; Models, Molecular; Molecular Conformation; Protein Binding; Serum Albumin; Serum Albumin, Bovine | 2017 |
Polyphenols in combination with β-cyclodextrin can inhibit and disaggregate α-synuclein amyloids under cell mimicking conditions: A promising therapeutic alternative.
Topics: alpha-Synuclein; Amyloid; Amyloidogenic Proteins; Animals; beta-Cyclodextrins; Catechin; Cell Line; Cell Survival; Circular Dichroism; Curcumin; Humans; Mice; Parkinson Disease; Polyphenols; Protein Aggregation, Pathological | 2017 |
Emulsifying Properties of Oxidatively Stressed Myofibrillar Protein Emulsion Gels Prepared with (-)-Epigallocatechin-3-gallate and NaCl.
Topics: Animals; Catechin; Emulsions; Gels; Muscle Proteins; Oxidation-Reduction; Sodium Chloride; Swine | 2017 |
Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats.
Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Antioxidants; Autophagy; Catechin; Hindlimb Suspension; Male; Muscle Fibers, Skeletal; Muscle, Skeletal; Muscular Atrophy; Organ Size; Rats; Rats, Inbred BN; Rats, Inbred F344; Signal Transduction | 2017 |
Flavan-3-ols and proanthocyanidins from Limonium brasiliense inhibit the adhesion of Porphyromonas gingivalis to epithelial host cells by interaction with gingipains.
Topics: Adhesins, Bacterial; Bacterial Adhesion; Benzopyrans; Catechin; Cysteine Endopeptidases; Epithelial Cells; Flavonoids; Gallic Acid; Gingipain Cysteine Endopeptidases; Humans; KB Cells; Plant Extracts; Plumbaginaceae; Porphyromonas gingivalis; Proanthocyanidins; Rhizome | 2017 |
Binding of tea catechins to rice bran protein isolate: Interaction and protective effect during in vitro digestion.
Topics: Adsorption; Biophysical Phenomena; Caffeine; Catechin; Digestion; Gastrointestinal Tract; Kinetics; Oryza; Plant Proteins; Seeds; Spectroscopy, Fourier Transform Infrared; Temperature | 2017 |
Mucus interactions with liposomes encapsulating bioactives: Interfacial tensiometry and cellular uptake on Caco-2 and cocultures of Caco-2/HT29-MTX.
Topics: Animals; beta Carotene; Caco-2 Cells; Catechin; Cell Survival; Coculture Techniques; Glycine max; HT29 Cells; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Intestinal Mucosa; Liposomes; Milk; Mucus; Rheology; Temperature | 2017 |
Interplay of myosin phosphatase and protein phosphatase-2A in the regulation of endothelial nitric-oxide synthase phosphorylation and nitric oxide production.
Topics: Animals; Catechin; Cattle; Cell Line; Electric Impedance; Enzyme Activation; Gene Silencing; Human Umbilical Vein Endothelial Cells; Humans; Marine Toxins; Models, Biological; Myosin-Light-Chain Phosphatase; Nitric Oxide; Nitric Oxide Synthase Type III; Oxazoles; Phosphorylation; Phosphothreonine; Protein Kinase C; Protein Phosphatase 2; Pulmonary Artery; Rabbits; RNA, Small Interfering; Tetradecanoylphorbol Acetate | 2017 |
(-)-Epigallocatechin-3-gallate stimulates myogenic differentiation through TAZ activation.
Topics: 14-3-3 Proteins; Acyltransferases; Animals; Catechin; Cell Differentiation; Cell Line; Gene Expression Regulation; HEK293 Cells; Humans; Mice; Mice, Inbred C57BL; Myoblasts; MyoD Protein; Myogenin; Myosin Heavy Chains; Primary Cell Culture; Protein Serine-Threonine Kinases; Satellite Cells, Skeletal Muscle; Signal Transduction; Tea; Transcription Factors | 2017 |
EGCG protects against homocysteine-induced human umbilical vein endothelial cells apoptosis by modulating mitochondrial-dependent apoptotic signaling and PI3K/Akt/eNOS signaling pathways.
Topics: Antioxidants; Apoptosis; Atherosclerosis; Catechin; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Mitochondria; Nitric Oxide Synthase Type III; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Signal Transduction | 2017 |
Correlation between the potency of flavonoids for cytochrome c reduction and inhibition of cardiolipin-induced peroxidase activity.
Topics: Animals; Anthocyanins; Ascorbic Acid; Cardiolipins; Catechin; Cytochromes c; Diphenylhexatriene; Flavonoids; Fluorescent Dyes; Horses; Kaempferols; Luteolin; Oxidation-Reduction; Peroxidases; Phosphatidylcholines; Protein Binding; Protein Conformation; Quercetin; Reducing Agents; Spectrometry, Fluorescence; Static Electricity; Unilamellar Liposomes | 2017 |
Comparison of binding interaction between β-lactoglobulin and three common polyphenols using multi-spectroscopy and modeling methods.
Topics: Catechin; Circular Dichroism; Coumaric Acids; Lactoglobulins; Polyphenols | 2017 |
Metabolomics analysis reveals the metabolic and functional roles of flavonoids in light-sensitive tea leaves.
Topics: Camellia sinensis; Catechin; Flavonoids; Glycosides; Light; Metabolic Networks and Pathways; Metabolomics; Plant Leaves; Reactive Oxygen Species | 2017 |
Implications of epigallocatechin-3-gallate in cultured human Sertoli cells glycolytic and oxidative profile.
Topics: Alanine; Catechin; Cell Proliferation; Cells, Cultured; Glucose; Glucose Transporter Type 2; Glycolysis; Humans; L-Lactate Dehydrogenase; Male; Membrane Potential, Mitochondrial; Monocarboxylic Acid Transporters; Muscle Proteins; Oxidative Stress; Pyruvic Acid; Sertoli Cells | 2017 |
Epigallocatechin-3-gallate inhibits bacterial virulence and invasion of host cells.
Topics: Bacterial Proteins; Catechin; Dose-Response Relationship, Drug; Epithelial Cells; HeLa Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Plant Extracts; Salmonella typhimurium; Structure-Activity Relationship; Tea | 2017 |
Epigallocatechin Gallate Inhibits Macaque SEVI-Mediated Enhancement of SIV or SHIV Infection.
Topics: Animals; Catechin; Macaca; Male; Mucous Membrane; Protease Inhibitors; Protein Binding; Semen; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Virus Attachment | 2017 |
Consumption of green tea epigallocatechin-3-gallate enhances systemic immune response, antioxidative capacity and HPA axis functions in aged male swiss albino mice.
Topics: Aging; Animals; Antibody Formation; Antioxidants; Catechin; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Hypothalamo-Hypophyseal System; Immunity, Cellular; Immunoglobulins; Leukocyte Count; Liver; Male; Mice; Oxidative Stress; Pituitary-Adrenal System; Real-Time Polymerase Chain Reaction; Tea | 2017 |
Anti-skin-aging effect of epigallocatechin gallate by regulating epidermal growth factor receptor pathway on aging mouse model induced by d-Galactose.
Topics: Animals; Catechin; ErbB Receptors; Galactose; Male; Mice; Models, Biological; Signal Transduction; Skin Aging | 2017 |
Preparation and characterization of (-)-Epigallocatechin-3-gallate (EGCG)-loaded nanoparticles and their inhibitory effects on Human breast cancer MCF-7 cells.
Topics: Anticarcinogenic Agents; Catechin; Cell Proliferation; Drug Carriers; Gene Expression Regulation; Humans; Inhibitory Concentration 50; MCF-7 Cells; Nanoparticles | 2017 |
Physicochemical characterization of the oolong tea polysaccharides with high molecular weight and their synergistic effects in combination with polyphenols on hepatocellular carcinoma.
Topics: Animals; Antioxidants; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Humans; Liver Neoplasms; Male; Mice; Molecular Weight; Plant Extracts; Polyphenols; Polysaccharides; Tea | 2017 |
Ameliorated Effects of (-)-Epigallocatechin Gallate Against Toxicity Induced by Vanadium in the Kidneys of Wistar Rats.
Topics: Acute Kidney Injury; Animals; Antioxidants; Catechin; Heavy Metal Poisoning; Hypertrophy; Injections, Intraperitoneal; Kidney; Kidney Glomerulus; Kidney Tubules; Lipid Peroxidation; Male; Oxidative Stress; Oxidoreductases; Protective Agents; Rats, Wistar; Vanadates; Vanadium; Vitamin A; Vitamin E | 2017 |
Inhibition of Myeloperoxidase- and Neutrophil-Mediated Hypochlorous Acid Formation in Vitro and Endothelial Cell Injury by (-)-Epigallocatechin Gallate.
Topics: Binding Sites; Catechin; Down-Regulation; Human Umbilical Vein Endothelial Cells; Humans; Hypochlorous Acid; Molecular Docking Simulation; Neutrophils; Peroxidase | 2017 |
(-)-Epigallocatechin-3-Gallate Inhibits Arsenic-Induced Inflammation and Apoptosis through Suppression of Oxidative Stress in Mice.
Topics: Animals; Apoptosis; Arsenic; Catechin; CD8-Positive T-Lymphocytes; Cytokines; Inflammation; Male; Mice; Mice, Inbred BALB C; Oxidative Stress; Oxidoreductases; Reactive Oxygen Species; T-Lymphocytes, Helper-Inducer | 2017 |
Physicochemical properties and cell-based bioactivity of Pu'erh tea polysaccharide conjugates.
Topics: Catechin; Cell Proliferation; Chemical Phenomena; DEAE-Cellulose; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Molecular Weight; Polysaccharides; Rosaniline Dyes; Steam; Tea; Temperature | 2017 |
Epigallocatechin-3-gallate Reduces Scavenger Receptor A Expression and Foam Cell Formation in Human Macrophages.
Topics: Catechin; Cell Line; Cholesterol; Foam Cells; Gene Expression; Humans; Macrophages; NF-kappa B; Receptors, Scavenger | 2017 |
Epigallocatechin gallate reverses cTnI-low expression-induced age-related heart diastolic dysfunction through histone acetylation modification.
Topics: Acetylation; Aging; Animals; Antioxidants; Catechin; Diastole; GATA4 Transcription Factor; Gene Expression Regulation; Heart; Histone Deacetylase 1; Histones; Mice, Inbred C57BL; Promoter Regions, Genetic; Protein Binding; Troponin I | 2017 |
Epigallocatechin-3-gallate ameliorates insulin resistance in hepatocytes.
Topics: Animals; Catechin; Cell Line, Tumor; Glucose; Glycogen; Hep G2 Cells; Hepatocytes; Humans; Insulin; Insulin Resistance; Male; Mice; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction | 2017 |
Possible use of epigallocatechin-3-gallate (EGCG) as prevention of radio dermatitis in radiotherapy treated breast cancer patients.
Topics: Antioxidants; Breast Neoplasms; Catechin; Female; Humans; Radiodermatitis; Treatment Outcome | 2017 |
Epigallocatechin gallate inhibits Streptococcus pneumoniae virulence by simultaneously targeting pneumolysin and sortase A.
Topics: A549 Cells; Aminoacyltransferases; Animals; Bacterial Proteins; Biofilms; Catechin; Cell Line, Tumor; Cysteine Endopeptidases; Female; Gene Expression Regulation, Bacterial; Humans; Lung; Mice, Inbred BALB C; Microbial Sensitivity Tests; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Streptolysins; Virulence | 2017 |
Immunomodulators targeting MARCO expression improve resistance to postinfluenza bacterial pneumonia.
Topics: Animals; Base Sequence; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Bronchoalveolar Lavage Fluid; Catechin; Cell Line; Cytokines; Disease Resistance; Host-Pathogen Interactions; Humans; Immunologic Factors; Influenza, Human; Interferon-gamma; Isothiocyanates; Macrophages, Alveolar; Male; MAP Kinase Kinase Kinases; Mice, Inbred C57BL; Models, Biological; Orthomyxoviridae Infections; Phagocytosis; Pneumonia, Bacterial; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Receptors, Immunologic; RNA, Messenger; Sequence Analysis, RNA; Signal Transduction; Staphylococcus aureus; Sulfoxides; Up-Regulation | 2017 |
Development and evaluation of resveratrol, Vitamin E, and epigallocatechin gallate loaded lipid nanoparticles for skin care applications.
Topics: Catechin; Drug Evaluation, Preclinical; Female; Humans; Lipid Metabolism; Lipids; Middle Aged; Nanoparticles; Organ Culture Techniques; Resveratrol; Skin; Skin Care; Stilbenes; Vitamin E | 2017 |
EGCG ameliorates diet-induced metabolic syndrome associating with the circadian clock.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Catechin; Circadian Clocks; Dietary Carbohydrates; Fructose; Liver; Metabolic Syndrome; Mice | 2017 |
Reduced prostate cancer risk with green tea and epigallocatechin 3-gallate intake among Hong Kong Chinese men.
Topics: Administration, Oral; Aged; Asian People; Case-Control Studies; Catechin; Hong Kong; Humans; Male; Middle Aged; Prostatic Neoplasms; Risk; Tea | 2017 |
Effect of Y6, an epigallocatechin gallate derivative, on reversing doxorubicin drug resistance in human hepatocellular carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Gene Expression; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms | 2017 |
Multi-site binding of epigallocatechin gallate to human serum albumin measured by NMR and isothermal titration calorimetry.
Topics: Binding Sites; Calorimetry; Catechin; Humans; Protein Binding; Serum Albumin, Human; Thermodynamics | 2017 |
An ortho-Iminoquinone Compound Reacts with Lysine Inhibiting Aggregation while Remodeling Mature Amyloid Fibrils.
Topics: alpha-Synuclein; Amyloid beta-Peptides; Animals; Catechin; Cell Survival; Cells, Cultured; Chickens; Dopaminergic Neurons; HEK293 Cells; Humans; Lysine; Methionine; Mice; Micrococcus luteus; Microtubule-Associated Proteins; Muramidase; Neuroprotective Agents; Oxidation-Reduction; Peptide Fragments; Protein Aggregation, Pathological; Quinones; Tyrosine 3-Monooxygenase | 2017 |
Antimicrobial mechanism of epigallocatechin gallate and gallocatechin gallate: They target 1-deoxy-d-xylulose 5-phosphate reductoisomerase, the key enzyme of the MEP terpenoid biosynthetic pathway.
Topics: Aldose-Ketose Isomerases; Anti-Bacterial Agents; Biosynthetic Pathways; Catechin; Enzyme Inhibitors; Escherichia coli; Humans; Molecular Docking Simulation; Terpenes | 2017 |
Epigallocatechin gallate protects BEAS-2B cells from lipopolysaccharide-induced apoptosis through upregulation of gastrin-releasing peptide.
Topics: Apoptosis; Blotting, Western; Bronchi; Catechin; Cell Line; Gastrin-Releasing Peptide; Humans; Lipopolysaccharides; Real-Time Polymerase Chain Reaction; Up-Regulation | 2017 |
Modulation of MMP-2 and -9 secretion by cytokines, inducers and inhibitors in human melanoma A-2058 cells.
Topics: Catechin; Cell Line, Tumor; Cytokines; Doxycycline; Humans; Interleukin-1beta; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Melanoma; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2017 |
Epigallocatechin gallate upregulates NRF2 to prevent diabetic nephropathy via disabling KEAP1.
Topics: Animals; Catechin; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Inflammation; Kelch-Like ECH-Associated Protein 1; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Oxidative Stress; RNA, Small Interfering; Signal Transduction; Up-Regulation | 2017 |
Probing the inhibitory activity of epigallocatechin-gallate on toxic aggregates of mutant (L84F) SOD1 protein through geometry based sampling and steered molecular dynamics.
Topics: Amyotrophic Lateral Sclerosis; Catalytic Domain; Catechin; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Mutation, Missense; Protein Aggregates; Protein Binding; Protein Conformation, alpha-Helical; Superoxide Dismutase-1; Thermodynamics | 2017 |
Intraperitoneal injection of (-)-Epigallocatechin-3-gallate protects against light-induced photoreceptor degeneration in the mouse retina.
Topics: Animals; Antioxidants; Catechin; Electroretinography; Injections, Intraperitoneal; Light; Male; Mice; Mice, Inbred BALB C; Oxidative Stress; Photoreceptor Cells, Vertebrate; Radiation Injuries, Experimental; Real-Time Polymerase Chain Reaction; Retina; Retinal Degeneration; RNA, Messenger; Superoxide Dismutase; Tomography, Optical Coherence | 2017 |
In vitro evaluation of combination of EGCG and Erlotinib with classical chemotherapeutics on JAR cells.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Catechin; Cell Line, Tumor; Choriocarcinoma; Dactinomycin; Enzyme Activation; Erlotinib Hydrochloride; Gene Expression Regulation, Neoplastic; Humans; Methotrexate; Receptor, ErbB-2; RNA, Messenger | 2017 |
Activation of transforming growth factor-β1 by thrombin via integrins αvβ1, αvβ3, and αvβ5 in buccal fibroblasts: Suppression by epigallocatechin-3-gallate.
Topics: Blotting, Western; Catechin; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Humans; Integrin alphaVbeta3; Mouth Mucosa; Oral Submucous Fibrosis; Receptors, Vitronectin; Sensitivity and Specificity; Thrombin; Transforming Growth Factor beta1 | 2017 |
EGFR inhibition by (-)-epigallocatechin-3-gallate and IIF treatments reduces breast cancer cell invasion.
Topics: Basigin; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Movement; Down-Regulation; ErbB Receptors; Female; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; MCF-7 Cells; Neoplasm Invasiveness; Phenanthrenes; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction; Tissue Inhibitor of Metalloproteinase-1 | 2017 |
Mechanism of Anti-rotavirus Synergistic Activity by Epigallocatechin Gallate and a Proanthocyanidin-Containing Nutraceutical.
Topics: Antiviral Agents; Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Drug Synergism; Mass Spectrometry; Phytochemicals; Plant Extracts; Proanthocyanidins; Rotavirus; Vaccinium macrocarpon | 2017 |
Study on the pharmacokinetics of deoxyschizandrin and schizandrin in combination with epigallocatechin gallate, a component of green tea, in rats.
Topics: Animals; Caco-2 Cells; Catechin; Cyclooctanes; Female; Humans; Lignans; Male; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Tea | 2018 |
Epigallocatechin-3-gallate ameliorates intrahepatic cholestasis of pregnancy by inhibiting matrix metalloproteinase-2 and matrix metalloproteinase-9.
Topics: Animals; Antioxidants; Catechin; Cholestasis, Intrahepatic; Ethinyl Estradiol; Female; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Pregnancy; Pregnancy Complications; Rats | 2017 |
Epigallocatechin-3-gallate (EGCG) consumption in the Ts65Dn model of Down syndrome fails to improve behavioral deficits and is detrimental to skeletal phenotypes.
Topics: Administration, Oral; Animals; Brain; Catechin; Cognition; Disease Models, Animal; Down Syndrome; Dyrk Kinases; Femur; Male; Maze Learning; Mice, Inbred C3H; Mice, Transgenic; Motor Activity; Phenotype; Protease Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Random Allocation; Recognition, Psychology; Treatment Failure | 2017 |
Epigallocatechin-3-gallate counters cisplatin toxicity of rat testes.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Apoptosis; Catechin; Cisplatin; Dose-Response Relationship, Drug; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Tea; Testis; Testosterone; Tumor Necrosis Factor-alpha | 2017 |
Effect of epigallocatechin-3-gallate on the increase in type II collagen accumulation in cartilage-like MSC sheets.
Topics: Aged; Bone Marrow Cells; Cartilage; Catechin; Cell Differentiation; Chondrocytes; Chondrogenesis; Collagen Type II; Culture Media; Gene Expression Regulation; Humans; Male; Matrix Metalloproteinase 13; Mesenchymal Stem Cells; Primary Cell Culture; Proteolysis; Reactive Oxygen Species; SOX9 Transcription Factor; Tissue Engineering | 2017 |
α-Syntrophin stabilizes catalase to reduce endogenous reactive oxygen species levels during myoblast differentiation.
Topics: Aldehydes; Animals; Antioxidants; Blotting, Western; Calcium-Binding Proteins; Catalase; Catechin; Cell Differentiation; Cell Line; Cysteine Proteinase Inhibitors; Leupeptins; Membrane Proteins; Mice; Microscopy, Fluorescence, Multiphoton; Muscle Development; Muscle Proteins; Myoblasts; Oxidative Stress; Protein Stability; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference | 2017 |
Epigallocatechin gallate has pleiotropic effects on transmembrane signaling by altering the embedding of transmembrane domains.
Topics: Amino Acid Substitution; Animals; Antioxidants; Catechin; CHO Cells; Cricetulus; Dietary Supplements; Dimerization; ErbB Receptors; Humans; Integrin alpha2; Integrin beta3; Ligands; Lipid Bilayers; Models, Molecular; Mutation; Peptide Fragments; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Interaction Domains and Motifs; Recombinant Fusion Proteins; Signal Transduction; Talin | 2017 |
Bioinformatics Analysis on Molecular Mechanism of Green Tea Compound Epigallocatechin-3-Gallate Against Ovarian Cancer.
Topics: Catechin; Computational Biology; Female; Gene Regulatory Networks; Humans; Ovarian Neoplasms; Protein Interaction Maps; Signal Transduction; Tea | 2017 |
Green Tea Polyphenols, Mimicking the Effects of Dietary Restriction, Ameliorate High-Fat Diet-Induced Kidney Injury via Regulating Autophagy Flux.
Topics: Acute Kidney Injury; AMP-Activated Protein Kinases; Animals; Antioxidants; Autophagy; Blood Glucose; Catechin; Cell Line; Cholesterol; Creatinine; Cystatin C; Diet, High-Fat; Epithelial Cells; Humans; Kidney; Male; Phosphorylation; Polyphenols; Rats; Rats, Wistar; Tea; Triglycerides | 2017 |
PDE3 inhibitor and EGCG combination treatment suppress cancer stem cell properties in pancreatic ductal adenocarcinoma.
Topics: Animals; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Catechin; Cell Line, Tumor; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Disease Models, Animal; Drug Synergism; Fluorescent Antibody Technique; Gene Expression; Humans; Mice; Neoplastic Stem Cells; Phosphodiesterase 3 Inhibitors; Xenograft Model Antitumor Assays | 2017 |
(-)-Epigallocatechin-3-gallate ameliorates memory impairment and rescues the abnormal synaptic protein levels in the frontal cortex and hippocampus in a mouse model of Alzheimer's disease.
Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Catechin; Disease Models, Animal; Disks Large Homolog 4 Protein; Frontal Lobe; Hippocampus; Maze Learning; Memory Disorders; Mice; Motor Activity; Neuroprotective Agents; Nootropic Agents; Peptide Fragments; Phosphorylation; Random Allocation; Spatial Memory; Synaptophysin; tau Proteins | 2017 |
Molecular insights into the differences in anti-inflammatory activities of green tea catechins on IL-1β signaling in rheumatoid arthritis synovial fibroblasts.
Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Catalytic Domain; Catechin; Cells, Cultured; Cyclooxygenase 2 Inhibitors; Fibroblasts; Humans; Interleukin-1beta; Interleukin-6; Interleukin-8; MAP Kinase Kinase Kinases; Matrix Metalloproteinase 2; Molecular Docking Simulation; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Phytotherapy; Plants, Medicinal; Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-jun; Signal Transduction; Synovial Membrane; Tea | 2017 |
(-)-Epigallocatechin-3-gallate inhibits human angiotensin-converting enzyme activity through an autoxidation-dependent mechanism.
Topics: Allosteric Regulation; Angiotensin-Converting Enzyme Inhibitors; Catechin; Cell Line, Tumor; Humans; Peptidyl-Dipeptidase A | 2017 |
Transcriptomic analysis of the response of Pseudomonas fluorescens to epigallocatechin gallate by RNA-seq.
Topics: Bacterial Proteins; Catechin; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Gene Regulatory Networks; Iron; Oxidative Stress; Pseudomonas fluorescens; Sequence Analysis, RNA; Tea | 2017 |
Inhibitory mechanism of five natural flavonoids against murine norovirus.
Topics: Animals; Antiviral Agents; Catechin; Cell Line; Cytokines; Drug Evaluation, Preclinical; Flavonoids; Flavonols; Gene Expression Regulation; Interleukin-6; Isoflavones; Mice; Nitric Oxide Synthase Type II; Norovirus; Quercetin; Up-Regulation; Virus Replication | 2017 |
Green tea epigallocatechin gallate enhances cardiac function restoration through survival signaling expression in diabetes mellitus rats with autologous adipose tissue-derived stem cells.
Topics: Adipose Tissue; Administration, Oral; Animals; Apoptosis; Biomarkers; Blood Glucose; Catechin; Cell Survival; Cells, Cultured; Combined Modality Therapy; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Echocardiography; Male; Myocytes, Cardiac; Rats, Wistar; Recovery of Function; Signal Transduction; Stem Cell Transplantation | 2017 |
Anti-inflammatory effect of epigallocatechin gallate in a mouse model of ovalbumin-induced allergic rhinitis.
Topics: Allergens; Animals; Anti-Inflammatory Agents; Catechin; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Female; Histamine; Humans; Immunoglobulin E; Inflammation Mediators; Mice; Mice, Inbred BALB C; Ovalbumin; Rhinitis, Allergic; Sneezing; Tea | 2017 |
Some Physical Properties of Protein Moiety of Alkali-Extracted Tea Polysaccharide Conjugates Were Shielded by Its Polysaccharide.
Topics: Catechin; Glycoconjugates; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Liquid-Liquid Extraction; Plant Proteins; Polysaccharides; Rosaniline Dyes; Sodium Hydroxide; Spectrophotometry, Ultraviolet; Tea | 2017 |
Epigallocatechin-3-gallate attenuates cerebral cortex damage and promotes brain regeneration in acrylamide-treated rats.
Topics: Acrylamide; Animals; beta-Galactosidase; Brain Diseases; Brain-Derived Neurotrophic Factor; Camellia sinensis; Catechin; Cerebral Cortex; Cyclooxygenase 2; Humans; Male; Neuroprotective Agents; Nitric Oxide Synthase Type II; Plant Extracts; Rats; Rats, Sprague-Dawley; Regeneration; Tea | 2017 |
Quantification of Oral Roughness Perception and Comparison with Mechanism of Astringency Perception.
Topics: Adult; Age Factors; Area Under Curve; Astringents; Catechin; Female; Humans; Male; Middle Aged; ROC Curve; Salivation; Tannins; Taste Perception; Young Adult | 2017 |
Evaluation of nanohydroxyapaptite (nano-HA) coated epigallocatechin-3-gallate (EGCG) cross-linked collagen membranes.
Topics: Animals; Bone Regeneration; Catechin; Collagen; Durapatite; Membranes, Artificial; Osteogenesis; Rats | 2017 |
Preparation and characterization of antioxidant edible chitosan films incorporated with epigallocatechin gallate nanocapsules.
Topics: Antioxidants; Catechin; Chitosan; Food Packaging; Nanocapsules; Permeability | 2017 |
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Humans; Neoplastic Stem Cells; Tea; Wnt Signaling Pathway | 2017 |
Targeting epithelial-mesenchymal transition: Metal organic network nano-complexes for preventing tumor metastasis.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Cell Movement; Doxorubicin; Drug Delivery Systems; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Iron; Metal Nanoparticles; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Xenograft Model Antitumor Assays | 2017 |
Influence of the dual combination of silymarin and (-)-epigallocatechin gallate, natural dietary flavonoids, on the pharmacokinetics of oxcarbazepine in rats.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Catechin; Flavonoids; Humans; Male; Oxcarbazepine; Rats; Rats, Wistar; Silymarin | 2017 |
Green tea and epigallocatechin-3-gallate are bactericidal against Bacillus anthracis.
Topics: Anthrax; Anti-Bacterial Agents; Bacillus anthracis; Catechin; Humans; Tea; Virulence | 2017 |
Oral astringent stimuli alter the enamel pellicle's ultrastructure as revealed by electron microscopy.
Topics: Adult; Aluminum Chloride; Aluminum Compounds; Animals; Astringents; Bacterial Adhesion; Catechin; Cattle; Chitosan; Chlorides; Dental Enamel; Dental Pellicle; Ferric Compounds; Humans; Materials Testing; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Mouth; Muramidase; Polyphenols; Preventive Dentistry; Salivary Proteins and Peptides; Spectrometry, X-Ray Emission; Surface Properties; Time Factors; Tooth Attrition; Tooth Erosion | 2017 |
Effect of gels containing chlorhexidine or epigallocatechin-3-gallate on the protein composition of the acquired enamel pellicle.
Topics: Adult; Calcium-Binding Proteins; Catechin; Chlorhexidine; Citric Acid; Cystatins; Dental Pellicle; Female; Gels; Humans; Male; Middle Aged; Profilins; Proteomics; Salivary Proteins and Peptides; Up-Regulation | 2017 |
Formulation and characterization of EGCG for the treatment of superficial bladder cancer.
Topics: Anticarcinogenic Agents; Catechin; Chromatography, High Pressure Liquid; Cold Temperature; Filtration; Freeze Drying; Humans; Radiation, Ionizing; Sterilization; Urinary Bladder Neoplasms | 2017 |
Response of renal tubular cells to differential types and doses of calcium oxalate crystals: Integrative proteome network analysis and functional investigations.
Topics: Animals; Antioxidants; Calcium Oxalate; Catechin; Dogs; Kidney Tubules; Madin Darby Canine Kidney Cells; Oxidation-Reduction; Oxidative Stress; Protein Interaction Maps; Proteome; Proteomics; Ubiquitination | 2017 |
Effect of Green Tea Polyphenol Epigallocatechin-3-gallate on the Aggregation of αA(66-80) Peptide, a Major Fragment of αA-crystallin Involved in Cataract Development.
Topics: alpha-Crystallin A Chain; Amino Acid Sequence; Amyloid; Antioxidants; Cataract; Catechin; Dose-Response Relationship, Drug; Humans; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Molecular Sequence Data; Peptide Fragments; Protein Aggregation, Pathological; Tea | 2017 |
Epigallocatechin-3-gallate and related phenol compounds redirect the amyloidogenic aggregation pathway of ataxin-3 towards non-toxic aggregates and prevent toxicity in neural cells and Caenorhabditis elegans animal model.
Topics: Amyloid; Amyloidogenic Proteins; Animals; Ataxin-3; Caenorhabditis elegans; Catechin; Disease Models, Animal; Humans; Hydrogen Bonding; Molecular Docking Simulation; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Nuclear Proteins; Peptides; Phenols | 2017 |
Salts Influence Cathechins and Flavonoids Encapsulation in Liposomes: A Molecular Dynamics Investigation.
Topics: Catechin; Flavonoids; Liposomes; Molecular Dynamics Simulation | 2017 |
Green tea polyphenols ameliorate non-alcoholic fatty liver disease through upregulating AMPK activation in high fat fed Zucker fatty rats.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Antioxidants; Catechin; Diet, High-Fat; Disease Models, Animal; Humans; Lipid Metabolism; Lipogenesis; Liver; Liver Function Tests; Male; Non-alcoholic Fatty Liver Disease; Phosphorylation; Polyphenols; Rats; Rats, Zucker; Signal Transduction; Sterol Regulatory Element Binding Protein 1; Tea; Transcriptional Activation; Triglycerides; Up-Regulation; Weight Gain | 2017 |
Potential chemotherapeutic effects of diosgenin, zoledronic acid and epigallocatechin-3-gallate on PE/CA-PJ15 oral squamous cancer cell line.
Topics: Apoptosis; Carcinoma, Squamous Cell; Catechin; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Diosgenin; Diphosphonates; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Imidazoles; Mouth Neoplasms; Zoledronic Acid | 2017 |
Modulation of cisplatin cytotoxic activity against leiomyosarcoma cells by epigallocatechin-3-gallate.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Catechin; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cisplatin; Inhibitory Concentration 50; Leiomyosarcoma; Mitochondria; Rats, Wistar | 2018 |
Green tea polyphenol EGCG causes anti-cancerous epigenetic modulations in acute promyelocytic leukemia cells.
Topics: Acetylation; Antineoplastic Agents, Phytogenic; Apoptosis; Biomarkers; Catechin; Cell Cycle Checkpoints; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Leukemic; Histones; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Polyphenols; Promoter Regions, Genetic; Tea | 2018 |
Epigallocatechin-3-gallate promotes apoptosis in human breast cancer T47D cells through down-regulation of PI3K/AKT and Telomerase.
Topics: Antioxidants; Apoptosis; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Survival; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Telomerase | 2017 |
Epigallocatechin-3-gallate inhibit replication of white spot syndrome virus in Scylla paramamosain.
Topics: Animals; Antiviral Agents; Aquaculture; Brachyura; Catechin; Immunity, Innate; White spot syndrome virus 1 | 2017 |
Effect of the Biphenyl Neolignan Honokiol on Aβ
Topics: Amyloid beta-Peptides; Animals; Biphenyl Compounds; Caenorhabditis elegans; Catechin; Chelating Agents; Cholinesterase Inhibitors; Drug Stability; Free Radical Scavengers; Humans; Iron; Lignans; Molecular Docking Simulation; Molecular Structure; Neuroprotective Agents; Paralysis; Peptide Fragments; Picrates; Protein Aggregation, Pathological; Protein Multimerization; Resveratrol; Stilbenes | 2017 |
Epigallocatechin gallate inhibits the type III secretion system of Gram-negative enteropathogenic bacteria under model conditions.
Topics: Adenosine Triphosphatases; Bacterial Outer Membrane Proteins; Catechin; Cell Line; Culture Media; Enterohemorrhagic Escherichia coli; Enteropathogenic Escherichia coli; Escherichia coli Proteins; Food Microbiology; Humans; Salmonella typhi; Type III Secretion Systems; Virulence Factors; Yersinia pseudotuberculosis | 2017 |
Effects of Epigallocatechin-3-gallate (EGCG) on the bond strength of fiber posts to Sodium hypochlorite (NaOCl) treated intraradicular dentin.
Topics: Catechin; Dental Pulp Cavity; Dentin; Dentin-Bonding Agents; Humans; Resin Cements; Root Canal Filling Materials; Root Canal Irrigants; Sodium Hypochlorite | 2017 |
EGCG inhibits the oligomerization of amyloid beta (16-22) hexamer: Theoretical studies.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Catechin; Molecular Dynamics Simulation; Peptide Fragments; Protein Conformation, beta-Strand; Static Electricity | 2017 |
Epigallocatechin-3-Gallate Protects against Homocysteine-Induced Brain Damage in Rats.
Topics: Animals; Blotting, Western; Brain; Brain Damage, Chronic; Catechin; Glial Fibrillary Acidic Protein; Glutathione; Homocysteine; Interleukin-1beta; Male; Malondialdehyde; Maze Learning; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2018 |
Epigallocatechin gallate, an active green tea compound inhibits the Zika virus entry into host cells via binding the envelope protein.
Topics: Antiviral Agents; Catechin; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Binding; Protein Conformation; Tea; Thermodynamics; Viral Envelope Proteins; Virus Internalization; Zika Virus | 2017 |
Influence of EGCG on α-synuclein (αS) aggregation and identification of their possible binding mode: A computational study using molecular dynamics simulation.
Topics: alpha-Synuclein; Binding Sites; Catechin; Humans; Hydrogen Bonding; Molecular Dynamics Simulation; Protein Structure, Secondary; Protein Structure, Tertiary; Thermodynamics | 2018 |
Effects of epigallocatechin‑3‑gallate on iron metabolism in spinal cord motor neurons.
Topics: Animals; Catechin; Female; Iron; Lipid Peroxidation; Male; Motor Neurons; Rats, Sprague-Dawley; Spinal Cord | 2017 |
Protective effects of a green tea polyphenol, epigallocatechin-3-gallate, against sevoflurane-induced neuronal apoptosis involve regulation of CREB/BDNF/TrkB and PI3K/Akt/mTOR signalling pathways in neonatal mice.
Topics: Animals; Animals, Newborn; Apoptosis; Brain-Derived Neurotrophic Factor; Caspase 3; Catechin; Cell Survival; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cytoprotection; Gene Expression Regulation, Enzymologic; Memory; Methyl Ethers; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Polyphenols; Proto-Oncogene Proteins c-akt; Receptor, trkB; Sevoflurane; Signal Transduction; Spatial Behavior; Tea; TOR Serine-Threonine Kinases | 2017 |
Ferritin glycosylated by chitosan as a novel EGCG nano-carrier: Structure, stability, and absorption analysis.
Topics: Absorption, Physicochemical; Biological Availability; Caco-2 Cells; Catechin; Chitosan; Drug Carriers; Drug Stability; Ferritins; Gastrointestinal Tract; Glycosylation; Humans; Nanoparticles; Particle Size | 2017 |
Epigallocatechin Gallate Attenuates Hip Fracture-Induced Acute Lung Injury by Limiting Mitochondrial DNA (mtDNA) Release.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Catechin; Cytokines; DNA, Mitochondrial; Enzyme-Linked Immunosorbent Assay; Hip Fractures; Lung; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction | 2017 |
NRF2 Plays a Critical Role in Both Self and EGCG Protection against Diabetic Testicular Damage.
Topics: Animals; Apoptosis; Blotting, Western; Catechin; Diabetes Complications; Diabetes Mellitus, Experimental; Endoplasmic Reticulum Stress; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Testis | 2017 |
Development of Epigallocatechin-3-gallate-Encapsulated Nanohydroxyapatite/Mesoporous Silica for Therapeutic Management of Dentin Surface.
Topics: Catechin; Dentin; Microscopy, Electron, Scanning; Porosity; Silicon Dioxide; Streptococcus mutans | 2017 |
Catechin Composition and Antioxidant Activity of Black Teas in Relation to Brewing Time.
Topics: Antioxidants; Catechin; Chromatography, Liquid; Cooking; Gallic Acid; Limit of Detection; Mass Spectrometry; Reproducibility of Results; Tea; Time Factors | 2017 |
Discovery of a potent angiotensin converting enzyme inhibitor via virtual screening.
Topics: Angiotensin-Converting Enzyme Inhibitors; Binding Sites; Catechin; Chalcones; Drug Evaluation, Preclinical; Humans; Molecular Docking Simulation; Peptidyl-Dipeptidase A; Protein Binding; Protein Structure, Tertiary; Pyrrolizidine Alkaloids | 2017 |
Epigallocatechin gallate attenuates overload‑induced cardiac ECM remodeling via restoring T cell homeostasis.
Topics: Animals; Catechin; Cell Differentiation; Cytokines; Extracellular Matrix; Fibrosis; Homeostasis; Lymphocyte Activation; Male; Myocardium; Rats, Sprague-Dawley; T-Lymphocytes; T-Lymphocytes, Regulatory; Th17 Cells | 2017 |
(-)-Epigallocatechin-3-gallate attenuates myocardial injury induced by ischemia/reperfusion in diabetic rats and in H9c2 cells under hyperglycemic conditions.
Topics: Animals; Apoptosis; Cardiotonic Agents; Catechin; Diabetes Mellitus, Experimental; Hyperglycemia; Male; Malondialdehyde; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Rats, Sprague-Dawley; Sirtuin 1; Superoxide Dismutase | 2017 |
Arecoline activates latent transforming growth factor β1 via mitochondrial reactive oxygen species in buccal fibroblasts: Suppression by epigallocatechin-3-gallate.
Topics: Areca; Arecoline; Blotting, Western; Catechin; Cells, Cultured; Connective Tissue Growth Factor; Early Growth Response Protein 1; Fibroblasts; Humans; Immunoassay; Mitochondria; Mouth Mucosa; Oral Submucous Fibrosis; Phosphorylation; Plant Extracts; Plants, Toxic; Reactive Oxygen Species; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta1 | 2018 |
Adsorption of galloyl catechin aggregates significantly modulates membrane mechanics in the absence of biochemical cues.
Topics: Adsorption; Calorimetry, Differential Scanning; Catechin; Circular Dichroism; Dynamic Light Scattering; Humans; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Microscopy, Atomic Force | 2017 |
Cellular antioxidant, methylglyoxal trapping, and anti-inflammatory activities of cocoa tea (Camellia ptilophylla Chang).
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Camellia; Camellia sinensis; Catechin; Cell Line; China; Hep G2 Cells; Humans; Interleukin-6; Kinetics; Macrophages; Mice; Plant Preparations; Pyruvaldehyde; RAW 264.7 Cells | 2017 |
Identification of Circulating miR-125b as a Potential Biomarker of Alzheimer's Disease in APP/PS1 Transgenic Mouse.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Biomarkers; Catechin; Cell Line, Tumor; Cognition Disorders; Disease Models, Animal; Gene Expression Regulation; Humans; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; MicroRNAs; Mutation; Neuroblastoma; Presenilin-1; Protease Inhibitors; RNA, Messenger | 2017 |
Bioactivity of Epigallocatechin Gallate Nanoemulsions Evaluated in Mice Model.
Topics: Animals; Antioxidants; Catechin; Drug Delivery Systems; Emulsions; Female; Male; Mice; Mice, Inbred C57BL; Nanostructures; Olive Oil | 2017 |
EGCG ameliorates high-fat- and high-fructose-induced cognitive defects by regulating the IRS/AKT and ERK/CREB/BDNF signaling pathways in the CNS.
Topics: Animals; Brain-Derived Neurotrophic Factor; Catechin; Cell Line; Cyclic AMP Response Element-Binding Protein; Dietary Carbohydrates; Dietary Fats; Extracellular Signal-Regulated MAP Kinases; Fructose; Insulin Receptor Substrate Proteins; Learning Disabilities; MAP Kinase Signaling System; Memory Disorders; Mice; Proto-Oncogene Proteins c-akt | 2017 |
Effect of epigallocatechin gallate on growth performance and antioxidant capacity in heat-stressed broilers.
Topics: AMP-Activated Protein Kinases; Animal Feed; Animals; Antioxidants; Catechin; Chickens; Diet; Dietary Supplements; Hot Temperature; Male; Metabolic Networks and Pathways; Random Allocation; Sirtuin 1; Stress, Physiological | 2017 |
Effects of epigallocatechin-3-gallate on systemic inflammation-induced cognitive dysfunction in aged rats.
Topics: Animals; Aspartate Aminotransferases; Catechin; Cognitive Dysfunction; Cytokines; Hippocampus; Inflammation; Lipopolysaccharides; Male; Memory Disorders; Microglia; Rats; Rats, Sprague-Dawley; Sepsis | 2017 |
Beneficial metabolic effects of dietary epigallocatechin gallate alone and in combination with exendin-4 in high fat diabetic mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adiposity; Alanine Transaminase; Animals; Blood Glucose; Body Weight; Catechin; Corticosterone; Diabetes Mellitus, Experimental; Diet, High-Fat; Drug Therapy, Combination; Energy Intake; Exenatide; Glucose Tolerance Test; Glutathione Reductase; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Insulin Resistance; Interleukin-6; Mice, Obese | 2018 |
Epigallocatechin-3-Gallate: The Prospective Targeting of Cancer Stem Cells and Preventing Metastasis of Chemically-Induced Mammary Cancer in Rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Catechin; Female; Mammary Neoplasms, Experimental; Neoplastic Stem Cells; Rats; Rats, Sprague-Dawley | 2017 |
Synergistic effects of combination treatment using EGCG and suramin against the chikungunya virus.
Topics: Antiviral Agents; Catechin; Chikungunya Fever; Chikungunya virus; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Humans; Suramin; Treatment Outcome | 2017 |
Fungal community succession and major components change during manufacturing process of Fu brick tea.
Topics: Catechin; DNA, Fungal; Fermentation; Food Industry; Fungi; Gallic Acid; High-Throughput Nucleotide Sequencing; Metabolomics; Sequence Analysis, DNA; Tea | 2017 |
Galloyl moieties enhance the binding of (-)-epigallocatechin-3-gallate to β-lactoglobulin: A spectroscopic analysis.
Topics: Catechin; Lactoglobulins; Polyphenols; Spectrum Analysis | 2017 |
An integrated antioxidant activity fingerprint for commercial teas based on their capacities to scavenge reactive oxygen species.
Topics: Antioxidants; Catechin; Chromatography, High Pressure Liquid; Reactive Oxygen Species; Tea | 2017 |
Folate-targeted nanostructured lipid carriers for enhanced oral delivery of epigallocatechin-3-gallate.
Topics: Catechin; Drug Carriers; Folic Acid; Humans; Lipids; Nanostructures | 2017 |
Epigallocatechin-3-gallate promotes all-trans retinoic acid-induced maturation of acute promyelocytic leukemia cells via PTEN.
Topics: Catechin; Cell Differentiation; Chromones; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Leupeptins; Morpholines; Phenanthrenes; Promyelocytic Leukemia Protein; Proteolysis; PTEN Phosphohydrolase; Retinoic Acid Receptor alpha; Tretinoin | 2017 |
A-type ECG and EGCG dimers inhibit 3T3-L1 differentiation by binding to cholesterol in lipid rafts.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Catechin; Cell Differentiation; Cholesterol; Dimerization; Lipid Bilayers; Membrane Microdomains; Mice; Microscopy, Fluorescence; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines | 2017 |
Epigallocatechin-3-gallate protects against diabetic cardiomyopathy through modulating the cardiometabolic risk factors, oxidative stress, inflammation, cell death and fibrosis in streptozotocin-nicotinamide-induced diabetic rats.
Topics: Animals; Apoptosis; Biomarkers; Cardiotonic Agents; Catechin; Cytokines; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Fibrosis; Male; Myocardium; Niacinamide; Oxidative Stress; Rats, Wistar; Risk Factors; Streptozocin | 2017 |
Possible role of antioxidative capacity of (-)-epigallocatechin-3-gallate treatment in morphological and neurobehavioral recovery after sciatic nerve crush injury.
Topics: Animals; Antioxidants; Axons; Catechin; Crush Injuries; Disease Models, Animal; Hyperalgesia; Male; Motor Activity; Nerve Regeneration; Neuroprotective Agents; Oxidative Stress; Peripheral Nerve Injuries; Random Allocation; Rats, Wistar; Recovery of Function; RNA, Messenger; Sciatic Nerve; Sciatic Neuropathy; Spinal Cord | 2017 |
Metal chelator EGCG attenuates Fe(III)-induced conformational transition of α-synuclein and protects AS-PC12 cells against Fe(III)-induced death.
Topics: alpha-Synuclein; Animals; Catechin; Cell Death; Cell Survival; Chelating Agents; Cytoprotection; Dose-Response Relationship, Drug; Ferric Compounds; PC12 Cells; Protein Conformation; Rats; Reactive Oxygen Species | 2017 |
Epigallocatechin-3-gallate inhibits H
Topics: Animals; Antioxidants; Aorta; Apoptosis; Catechin; Cells, Cultured; Hydrogen Peroxide; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Receptors, Laminin | 2017 |
Epigallocatechin Gallate as an anti-obesity therapeutic compound: an in silico approach for structure-based drug designing.
Topics: Adipocytes; Camellia sinensis; Catechin; Cell Differentiation; Computer Simulation; Drug Design; Humans; Molecular Docking Simulation; Obesity; Polyphenols; PPAR gamma; Tea; Transcription Factors | 2018 |
Thiol-Mediated Synthesis of Hyaluronic Acid-Epigallocatechin-3-O-Gallate Conjugates for the Formation of Injectable Hydrogels with Free Radical Scavenging Property and Degradation Resistance.
Topics: Animals; Catechin; Cell Line; Female; Free Radical Scavengers; Hyaluronic Acid; Hydrogels; Macrophages; Mice; Sulfhydryl Compounds; Tissue Distribution | 2017 |
The cytotoxic mechanism of epigallocatechin gallate on proliferative HaCaT keratinocytes.
Topics: Antineoplastic Agents; Catechin; Cell Line; Cells, Cultured; Condylomata Acuminata; Humans; Papillomaviridae; Papillomavirus Infections | 2017 |
(-)-Epigallocatechin-3-gallate and atorvastatin treatment down-regulates liver fibrosis-related genes in non-alcoholic fatty liver disease.
Topics: Animals; Atorvastatin; Catechin; Disease Models, Animal; Down-Regulation; Fibrillar Collagens; Gene Expression; Humans; Liver Cirrhosis; Male; Mice, Inbred C57BL; Multigene Family; Non-alcoholic Fatty Liver Disease | 2017 |
Destabilizing the interplay between miR-1275 and IGF2BPs by Tamarix articulata and quercetin in hepatocellular carcinoma.
Topics: Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Survival; Humans; Insulin-Like Growth Factor Binding Protein 2; Liver Neoplasms; MicroRNAs; Quercetin; Tamaricaceae | 2018 |
Comparison of disaggregative effect of A-type EGCG dimer and EGCG monomer on the preformed bovine insulin amyloid fibrils.
Topics: Amyloid; Animals; Catechin; Cattle; Dimerization; Dynamic Light Scattering; Electrophoresis, Polyacrylamide Gel; Insulin; Microscopy, Electron, Transmission; Particle Size; Spectrometry, Fluorescence | 2017 |
Long-term supplementation with EGCG and beta-alanine decreases mortality but does not affect cognitive or muscle function in aged mice.
Topics: Animals; Behavior, Animal; beta-Alanine; Catechin; Cognition; Dietary Supplements; Longevity; Male; Maze Learning; Mice, Inbred BALB C; Models, Animal; Motor Activity; Muscle, Skeletal; Physical Endurance; Rotarod Performance Test; Time Factors | 2017 |
Impact of EGCG Supplementation on the Progression of Diabetic Nephropathy in Rats: An Insight into Fibrosis and Apoptosis.
Topics: Animals; Apoptosis; Catechin; Diabetic Nephropathies; Fibrosis; Humans; Kidney; Male; Prospective Studies; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta | 2017 |
Potential benefit of (-)-epigallocatechin-3-gallate for macrovascular complications in diabetes.
Topics: Catechin; Diabetic Angiopathies; Humans; Protective Agents | 2017 |
Combinatorial bioactive botanicals re-sensitize tamoxifen treatment in ER-negative breast cancer via epigenetic reactivation of ERα expression.
Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Catechin; Cell Line, Tumor; Disease Models, Animal; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Epigenesis, Genetic; Estrogen Receptor alpha; Heterografts; Humans; Isothiocyanates; Mice; Neoplasm Transplantation; Phytochemicals; Sulfoxides; Tamoxifen; Treatment Outcome | 2017 |
Epigallocatechin Gallate-Loaded Gelatin-g-Poly(N-Isopropylacrylamide) as a New Ophthalmic Pharmaceutical Formulation for Topical Use in the Treatment of Dry Eye Syndrome.
Topics: Acrylic Resins; Administration, Ophthalmic; Animals; Anti-Inflammatory Agents; Antioxidants; Catechin; Cells, Cultured; Drug Carriers; Drug Compounding; Dry Eye Syndromes; Gelatin; Humans; Materials Testing; Spectroscopy, Fourier Transform Infrared; Treatment Outcome | 2017 |
Molecular Mechanism for the (-)-Epigallocatechin Gallate-Induced Toxic to Nontoxic Remodeling of Aβ Oligomers.
Topics: Amyloid beta-Peptides; Catechin; Models, Molecular; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Stereoisomerism | 2017 |
Epigallocatechin gallate induces extracellular degradation of amyloid β-protein by increasing neprilysin secretion from astrocytes through activation of ERK and PI3K pathways.
Topics: Amyloid beta-Peptides; Animals; Astrocytes; Catechin; Cell Membrane; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Extracellular Space; Isoflavones; Neprilysin; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proteolysis; Rats, Sprague-Dawley | 2017 |
Position and orientation of gallated proanthocyanidins in lipid bilayer membranes: influence of polymerization degree and linkage type.
Topics: Algorithms; Catechin; Hydrogen Bonding; Lipid Bilayers; Molecular Conformation; Molecular Dynamics Simulation; Molecular Structure; Proanthocyanidins | 2018 |
Amplification by (‑)‑epigallocatechin gallate of prostaglandin F2α‑stimulated synthesis of osteoprotegerin in osteoblasts.
Topics: Animals; Catechin; Cell Line; Chlorogenic Acid; Dinoprost; Drug Synergism; Gene Expression Regulation; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 8; Osteoblasts; Osteoprotegerin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; RNA, Messenger; Signal Transduction | 2017 |
Epigallocatechin-3-gallate inhibits TLR4 signaling through the 67-kDa laminin receptor and effectively alleviates acute lung injury induced by H9N2 swine influenza virus.
Topics: Acute Lung Injury; Animals; Antiviral Agents; Catechin; Female; Gene Expression Regulation; Inflammation Mediators; Influenza A Virus, H9N2 Subtype; Lung; Mice; Mice, Inbred BALB C; NF-kappa B; Orthomyxoviridae Infections; Oxidative Stress; Receptors, Laminin; Signal Transduction; Swine; Toll-Like Receptor 4 | 2017 |
(-)-Epigallocatechin-3-gallate Ameliorates Insulin Resistance and Mitochondrial Dysfunction in HepG2 Cells: Involvement of Bmal1.
Topics: AMP-Activated Protein Kinases; Animals; ARNTL Transcription Factors; Catechin; Cells, Cultured; Circadian Clocks; Glucosamine; Glucose; Hep G2 Cells; Hepatocytes; Humans; Insulin Resistance; Insulin-Like Growth Factor I; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Mitochondria, Liver; Oxidative Stress | 2017 |
Epigallocatechin gallate protects against homocysteine-induced vascular smooth muscle cell proliferation.
Topics: Catechin; Cell Line; Cell Proliferation; Homocysteine; Humans; MAP Kinase Signaling System; Muscle Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle | 2018 |
Comparison of α-Synuclein Fibril Inhibition by Four Different Amyloid Inhibitors.
Topics: alpha-Synuclein; Amphotericin B; Amyloid; Binding Sites; Catechin; Dopamine; Kinetics; Neuroprotective Agents; Protein Binding | 2017 |
Green tea supplementation produces better neuroprotective effects than red and black tea in Alzheimer-like rat model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Behavior, Animal; Body Weight; Catechin; Disease Models, Animal; Hippocampus; Male; Memory; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Tea | 2017 |
Binding of Gallic Acid and Epigallocatechin Gallate to Heat-Unfolded Whey Proteins at Neutral pH Alters Radical Scavenging Activity of in Vitro Protein Digests.
Topics: Catechin; Digestion; Free Radical Scavengers; Gallic Acid; Hot Temperature; Hydrogen-Ion Concentration; Phenols; Protein Unfolding; Whey Proteins | 2017 |
Electrochemical assay for continuous monitoring of dynamic DNA methylation process.
Topics: Biosensing Techniques; Catechin; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Drug Evaluation, Preclinical; Electrochemical Techniques; Electron Transport; Enzyme Inhibitors; Gold; Humans; Metal Nanoparticles; Models, Molecular | 2018 |
Blood-Brain Barrier Permeability of Green Tea Catechin Metabolites and their Neuritogenic Activity in Human Neuroblastoma SH-SY5Y Cells.
Topics: Blood-Brain Barrier; Catechin; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Humans; Lactones; Neurites; Neuroblastoma; Pyrogallol; Tea | 2017 |
Evaluation of Epigallocatechin-3-gallate Modified Collagen Membrane and Concerns on Schwann Cells.
Topics: Catechin; Cell Differentiation; Cell Proliferation; Collagen; Enzyme-Linked Immunosorbent Assay; Humans; Nerve Regeneration; Reactive Oxygen Species; Schwann Cells; Signal Transduction; Tea | 2017 |
A green tea polyphenol epigallocatechin-3-gallate enhances neuroregeneration after spinal cord injury by altering levels of inflammatory cytokines.
Topics: Animals; Axons; Behavior, Animal; Catechin; Cytokines; Inflammation Mediators; Male; Myelitis; Nerve Regeneration; Neuroprotective Agents; NF-kappa B; Rats, Wistar; Signal Transduction; Spinal Cord Injuries; Tea | 2017 |
Epigallocatechin‑3‑gallate protects from high glucose induced podocyte apoptosis via suppressing endoplasmic reticulum stress.
Topics: Animals; Apoptosis; Caspase 12; Catechin; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Nephropathies; eIF-2 Kinase; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Glucose; Heat-Shock Proteins; Membrane Proteins; Mice; Podocytes; Protective Agents; WT1 Proteins | 2017 |
Effects of herbal mixture extracts on obesity in rats fed a high-fat diet.
Topics: Animals; Anti-Obesity Agents; Catechin; Diet, High-Fat; Obesity; Rats | 2016 |
Extraction optimization of gallic acid, (+)-catechin, procyanidin-B2, (-)-epicatechin, (-)-epigallocatechin gallate, and (-)-epicatechin gallate: their simultaneous identification and quantification in Saraca asoca.
Topics: Catechin; Chromatography, High Pressure Liquid; Fabaceae; Gallic Acid; Proanthocyanidins; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry | 2017 |
Inhibition of Human and Rat Sucrase and Maltase Activities To Assess Antiglycemic Potential: Optimization of the Assay Using Acarbose and Polyphenols.
Topics: Acarbose; alpha-Glucosidases; Animals; Caco-2 Cells; Catechin; Enzyme Inhibitors; Glucose; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Intestine, Small; Kinetics; Polyphenols; Rats; Sucrase; Sucrase-Isomaltase Complex; Tea | 2017 |
(-)-Epigallocatechin-3-gallate and EZH2 inhibitor GSK343 have similar inhibitory effects and mechanisms of action on colorectal cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Enhancer of Zeste Homolog 2 Protein; Humans; Indazoles; Neoplasm Invasiveness; Pyridones | 2018 |
Refractory pouchitis improves after administration of the green tea polyphenol EGCG: a retrospective review.
Topics: Adult; Aged; Catechin; Endoscopy; Female; Humans; Male; Middle Aged; Pouchitis; Retrospective Studies; Tea; Treatment Outcome | 2018 |
(-)-Epigallocatechin-3-gallate enhances poly I:C-induced interferon-λ1 production and inhibits hepatitis C virus replication in hepatocytes.
Topics: Antiviral Agents; Catechin; Cell Line, Tumor; DEAD Box Protein 58; Enzyme-Linked Immunosorbent Assay; Hepacivirus; Hepatitis C; Hepatocytes; Humans; Immunity, Innate; Interferon-gamma; Interferon-Stimulated Gene Factor 3, gamma Subunit; Poly I-C; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Signal Transduction; Toll-Like Receptor 3; Viral Core Proteins; Virus Replication | 2017 |
Epigallocatechin-3-Gallate Ameliorates Angiotensin II-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells through the Activation of Nrf2/Caspase-3 Signaling.
Topics: Angiotensin II; Antioxidants; Apoptosis; Caspase 3; Caspase 9; Catechin; Cell Survival; Cells, Cultured; Cytochromes c; Cytoprotection; Dose-Response Relationship, Drug; Human Umbilical Vein Endothelial Cells; Humans; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species; Signal Transduction | 2017 |
Mitochondrial DNA‑induced inflammatory damage contributes to myocardial ischemia reperfusion injury in rats: Cardioprotective role of epigallocatechin.
Topics: Androstadienes; Animals; Catechin; Creatine Kinase; DNA, Mitochondrial; Enzyme-Linked Immunosorbent Assay; Interleukin-6; Interleukin-8; L-Lactate Dehydrogenase; Male; Myocardial Reperfusion Injury; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protective Agents; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Tumor Necrosis Factor-alpha; Wortmannin | 2017 |
Green Tea Polyphenol EGCG Upregulates Tollip Expression by Suppressing Elf-1 Expression.
Topics: Animals; Catechin; Cyclic GMP; DNA-Binding Proteins; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred BALB C; Nuclear Proteins; Protein Phosphatase 2; Second Messenger Systems; Tea; Toll-Like Receptor 4; Transcription Factors; Up-Regulation | 2017 |
Epigallocatechin-3-Gallate Inhibits Matrix Metalloproteinase-9 and Monocyte Chemotactic Protein-1 Expression Through the 67-κDa Laminin Receptor and the TLR4/MAPK/NF-κB Signalling Pathway in Lipopolysaccharide-Induced Macrophages.
Topics: Animals; Catechin; Chemokine CCL2; Down-Regulation; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Macrophages; Matrix Metalloproteinase 9; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; RAW 264.7 Cells; Receptors, Laminin; RNA Interference; RNA, Small Interfering; Signal Transduction; Toll-Like Receptor 4 | 2017 |
Hyaluronic acid-green tea catechin micellar nanocomplexes: Fail-safe cisplatin nanomedicine for the treatment of ovarian cancer without off-target toxicity.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Catechin; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Carriers; Drug Liberation; Female; Humans; Hyaluronic Acid; Mice, SCID; Micelles; Nanoconjugates; Ovarian Neoplasms; Oxidative Stress; Particle Size; Surface Properties; Tea; Tissue Distribution | 2017 |
Epigallocatechin-3-gallate promotes apoptosis and reversal of multidrug resistance in esophageal cancer cells.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; ATP Binding Cassette Transporter, Subfamily G, Member 2; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; Membrane Potential, Mitochondrial; Neoplasm Proteins; Signal Transduction; Time Factors | 2017 |
Synergistic toxicity of epigallocatechin-3-gallate and diethyldithiocarbamate, a lethal encounter involving redox-active copper.
Topics: Animals; Apoptosis; Catechin; Copper; Ditiocarb; DNA Damage; Lipid Peroxidation; Liver; Male; Mice; Models, Animal; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress | 2017 |
Effects of green tea epigallocatechin-3-gallate on the proteolipid protein and oligodendrocyte transcription factor 1 messenger RNA gene expression in a mouse model of multiple sclerosis.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Brain; Catechin; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Mice, Inbred C57BL; Multiple Sclerosis; Oligodendroglia; RNA, Messenger; Tea | 2017 |
In vitro assay to estimate tea astringency via observing flotation of artificial oil bodies sheltered by caleosin fused with histatin 3.
Topics: Astringents; Calcium-Binding Proteins; Catechin; Histatins; Humans; Lipid Droplets; Plant Proteins; Taste; Tea | 2017 |
Epigallocatechin-3-gallate promotes healthy lifespan through mitohormesis during early-to-mid adulthood in Caenorhabditis elegans.
Topics: Aging; Animals; Caenorhabditis elegans; Catechin; Longevity; Mitochondria; Organelle Biogenesis; Reactive Oxygen Species; Tea | 2018 |
A prodrug of green tea polyphenol (-)-epigallocatechin-3-gallate (Pro-EGCG) serves as a novel angiogenesis inhibitor in endometrial cancer.
Topics: Angiogenesis Inhibitors; Animals; Catechin; Cell Movement; Chemokine CXCL12; Endometrial Neoplasms; Female; Humans; Macrophages; Mice; Phosphoinositide-3 Kinase Inhibitors; Prodrugs; Tea; Vascular Endothelial Growth Factor A | 2018 |
In vitro study on anti-inflammatory effects of epigallocatechin-3-gallate-loaded nano- and microscale particles.
Topics: Anti-Inflammatory Agents; Catechin; Cell Death; Cell Survival; Dose-Response Relationship, Drug; Drug Liberation; Dynamic Light Scattering; Fibroblasts; Humans; Nanoparticles; Particle Size; Wound Healing | 2017 |
Polyphenol epigallocatechin-3-gallate alleviates high glucose-induced H9C2 cell damage through PI3K/Akt pathway.
Topics: Apoptosis; Catechin; Cell Line; Cell Survival; Glucose; Humans; Phosphatidylinositol 3-Kinases; Polyphenols; Protective Agents; Proto-Oncogene Proteins c-akt; Signal Transduction | 2017 |
Aggregation of Aβ(17-36) in the Presence of Naturally Occurring Phenolic Inhibitors Using Coarse-Grained Simulations.
Topics: Amyloid beta-Peptides; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Benzaldehydes; Catechin; Curcumin; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Protein Aggregates; Resveratrol; Stilbenes | 2017 |
Epigallocatechin-3-gallate reduces the proliferation of benign prostatic hyperplasia cells via regulation of focal adhesions.
Topics: Actin Cytoskeleton; Actins; Anticarcinogenic Agents; Catechin; Cell Line; Cell Movement; Cell Proliferation; Cell Survival; Focal Adhesions; Humans; Male; Prostatic Hyperplasia | 2017 |
Effect of (-)-epigallocatechin gallate (EGCG) extracted from green tea in reducing the formation of acrylamide during the bread baking process.
Topics: Acrylamide; Bread; Catechin; Tea; Triticum | 2018 |
Nanoemulsion delivery system of tea polyphenols enhanced the bioavailability of catechins in rats.
Topics: Animals; Biological Availability; Camellia sinensis; Catechin; Drug Delivery Systems; Emulsions; Male; Nanostructures; Plant Extracts; Polyphenols; Rats; Rats, Sprague-Dawley | 2018 |
Protective role of epigallocatechin-3-gallate on arsenic induced testicular toxicity in Swiss albino mice.
Topics: Animals; Antioxidants; Arsenic; Catechin; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Membrane Potential, Mitochondrial; Mice; Oxidative Stress; Protective Agents; Reproduction; Testis | 2017 |
Computational DNA binding studies of (-)-epigallocatechin-3-gallate.
Topics: Catechin; DNA; Intercalating Agents; Molecular Dynamics Simulation; Molecular Structure; Tea | 2018 |
(-)-Epigallocatechin-3-gallate Down-regulates Doxorubicin-induced Overexpression of P-glycoprotein Through the Coordinate Inhibition of PI3K/Akt and MEK/ERK Signaling Pathways.
Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B; Carcinoma, Hepatocellular; Catechin; Doxorubicin; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; MAP Kinase Signaling System; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Rhodamine 123; Signal Transduction; Tumor Cells, Cultured | 2017 |
Inflammation and oxidative stress in corneal tissue in experimental keratitis due to Fusarium solani: Amelioration following topical therapy with voriconazole and epigallocatechin gallate.
Topics: Administration, Topical; Animals; Antifungal Agents; Catechin; Cornea; Cytokines; Eye Infections, Fungal; Female; Fusarium; Inflammation; Keratitis; Male; Oxidative Stress; Rabbits; Voriconazole | 2018 |
Evaluation of epigallocatechin gallate and epicatechin gallate effects on acrylamide-induced neurotoxicity in rats and cytotoxicity in PC 12 cells.
Topics: Acrylamide; Animals; Catechin; Cell Survival; Cerebral Cortex; Eating; Glutathione; Lipid Peroxidation; Male; Neurotoxicity Syndromes; PC12 Cells; Rats; Rats, Wistar | 2018 |
Anti-oxidants correct disturbance of redox enzymes in the hearts of rat fetuses with congenital diaphragmatic hernia.
Topics: Acetophenones; Animals; Antioxidants; Catalase; Catechin; Disease Models, Animal; Female; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Hernias, Diaphragmatic, Congenital; Hydrogen Peroxide; Myocardium; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidase 4; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxide Dismutase | 2018 |
The anti-hyperuricemic effect of epigallocatechin-3-gallate (EGCG) on hyperuricemic mice.
Topics: Animals; Antioxidants; Catechin; Hyperuricemia; Male; Mice; Random Allocation; Tea; Treatment Outcome; Uric Acid | 2018 |
A new molecular mechanism underlying the EGCG-mediated autophagic modulation of AFP in HepG2 cells.
Topics: alpha-Fetoproteins; Autophagosomes; Autophagy; Binding Sites; Catechin; Cell Proliferation; Cytoskeleton; Dimerization; Hep G2 Cells; Humans; Membrane Potential, Mitochondrial; Microscopy, Fluorescence; Microtubule-Associated Proteins; Mitochondria; Molecular Dynamics Simulation; Protein Structure, Tertiary | 2017 |
Association of changes in ER stress-mediated signaling pathway with lead-induced insulin resistance and apoptosis in rats and their prevention by A-type dimeric epigallocatechin-3-gallate.
Topics: Animals; Apoptosis; Blood Glucose; Catechin; Cytochromes c; Dimerization; Diospyros; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Humans; Insulin; Insulin Resistance; Lead; Liver; Male; Metabolic Diseases; Oxidative Stress; Plant Extracts; Rats; Signal Transduction | 2017 |
Physical properties and antioxidant capacity of chitosan/epigallocatechin-3-gallate films reinforced with nano-bacterial cellulose.
Topics: Antioxidants; Catechin; Cellulose; Chitosan; Food Industry; Gluconacetobacter; Hydrogen Bonding; Oxygen; Permeability; Polymers; Rheology; Solubility; Tensile Strength; Thermogravimetry; Water | 2018 |
Polyphenol epigallocatechin-3-gallate inhibits hypoxia/reoxygenation-induced H9C2 cell apoptosis.
Topics: Apoptosis; Catechin; Cell Hypoxia; Cells, Cultured; Myocytes, Cardiac; Oxygen; Polyphenols | 2018 |
Antioxidant effects of epigallocatechin-3-gallate on the aTC1-6 pancreatic alpha cell line.
Topics: Animals; Antioxidants; Catechin; Cell Line; Dose-Response Relationship, Drug; Glucagon-Secreting Cells; Hydrogen Peroxide; Mice; Oxidative Stress; Reactive Oxygen Species | 2018 |
Green Tea Polyphenols Decrease Strecker Aldehydes and Bind to Proteins in Lactose-Hydrolyzed UHT Milk.
Topics: Aldehydes; Animals; Camellia sinensis; Catechin; Cattle; Food Additives; Food Handling; Hydrolysis; Lactose; Maillard Reaction; Milk; Milk Proteins; Plant Preparations; Polyphenols; Protein Binding; Tea; Temperature | 2017 |
Effects of flavonoids on MicroRNA 145 regulation through Klf4 and myocardin in neointimal formation in vitro and in vivo.
Topics: Angioplasty, Balloon; Angiotensin II; Animals; Carotid Arteries; Carotid Artery Injuries; Catechin; Cells, Cultured; Flavonoids; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; MicroRNAs; Muscle, Smooth, Vascular; Neointima; Nuclear Proteins; Rats, Wistar; Reproducibility of Results; RNA, Small Interfering; Trans-Activators | 2018 |
The Inhibitory Effects of Anthocyanin-Rich Sunrouge Tea on Pancreatic Lipase Activity.
Topics: Administration, Oral; Animals; Anthocyanins; Catechin; Enzyme Activation; In Vitro Techniques; Lipase; Male; Mice, Inbred ICR; Pancreas; Plant Extracts; Tea; Triglycerides; Water | 2017 |
Separation and purification of four phenolic compounds from persimmon by high-speed counter-current chromatography.
Topics: Antioxidants; Biphenyl Compounds; Catechin; Countercurrent Distribution; Diospyros; Fruit; Gallic Acid; Picrates; Plant Extracts | 2018 |
Effect of tea products on the in vitro enzymatic digestibility of starch.
Topics: Amylases; Catechin; Digestion; Flour; Food, Fortified; Glucan 1,4-alpha-Glucosidase; Glucose; Humans; Hydrolysis; Polyphenols; Postprandial Period; Starch; Tea; Triticum; Zea mays | 2018 |
NEAT1 acts as an inducer of cancer stem cell-like phenotypes in NSCLC by inhibiting EGCG-upregulated CTR1.
Topics: A549 Cells; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Catechin; Cation Transport Proteins; Copper Transporter 1; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neoplastic Stem Cells; Phenotype; RNA, Long Noncoding; Wnt Signaling Pathway | 2018 |
Epigallocatechin-3-O-gallate alleviates the malignant phenotype in A-431 epidermoid and SK-BR-3 breast cancer cell lines.
Topics: Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Membrane Potential, Mitochondrial; Molecular Structure; Reactive Oxygen Species | 2018 |
An efflux pump (MexAB-OprM) of Pseudomonas aeruginosa is associated with antibacterial activity of Epigallocatechin-3-gallate (EGCG).
Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Catechin; Dipeptides; Drug Resistance, Multiple, Bacterial; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 2017 |
Differential expression of microRNAs contributed to the health efficacy of EGCG in in vitro subarachnoid hemorrhage model.
Topics: Autophagy; Catechin; Cell Proliferation; Gene Expression Profiling; Humans; MicroRNAs; Signal Transduction; Subarachnoid Hemorrhage | 2017 |
Inhibition of Adipogenesis by Thiourea Derivatives.
Topics: Adipocytes; Adipogenesis; Animals; Anti-Obesity Agents; Antineoplastic Agents; Catechin; Cell Differentiation; Cell Line, Tumor; Curcumin; Humans; Inhibitory Concentration 50; Mice; Structure-Activity Relationship; Thiourea | 2018 |
Probing the inhibitory potency of epigallocatechin gallate against human γB-crystallin aggregation: Spectroscopic, microscopic and simulation studies.
Topics: Amino Acid Motifs; Amino Acids; Benzothiazoles; Catechin; Circular Dichroism; Computer Simulation; gamma-Crystallins; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kinetics; Nephelometry and Turbidimetry; Protein Aggregates; Protein Structure, Tertiary; Solutions; Spectrometry, Fluorescence; Thiazoles | 2018 |
Potential role of the mitochondria as a target for the hepatotoxic effects of (-)-epigallocatechin-3-gallate in mice.
Topics: Animals; Antioxidants; Biomarkers; Catechin; Chemical and Drug Induced Liver Injury; DNA Damage; Electron Transport Chain Complex Proteins; Gene Expression Regulation; Glutathione; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Oxidative Stress; Tea | 2018 |
Epigallocatechin 3-Gallate as an Inhibitor of Tau Phosphorylation and Aggregation: A Molecular and Structural Insight.
Topics: Catechin; Humans; Models, Molecular; Neuroprotective Agents; Nuclear Magnetic Resonance, Biomolecular; Phosphorylation; Protein Aggregation, Pathological; Protein Conformation; tau Proteins | 2017 |
Application of non-invasive low strength pulsed electric field to EGCG treatment synergistically enhanced the inhibition effect on PANC-1 cells.
Topics: Apoptosis; Catechin; Cell Line, Tumor; Electricity; Humans; Membrane Potential, Mitochondrial; Proto-Oncogene Proteins c-bcl-2 | 2017 |
Epigallocatechin-3-gallate enhances differentiation of acute promyelocytic leukemia cells via inhibition of PML-RARα and HDAC1.
Topics: Apoptosis; Catechin; Cell Differentiation; Cell Proliferation; Histone Deacetylase 1; Humans; Leukemia, Promyelocytic, Acute; Oncogene Proteins, Fusion | 2018 |
Effects of nutraceuticals on anaplastic thyroid cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Catechin; Cell Differentiation; Cell Growth Processes; Cell Line, Tumor; Curcumin; Dietary Supplements; Genistein; Humans; MicroRNAs; Resveratrol; Stilbenes; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms | 2018 |
(-)-Epigallocatechin-3-Gallate Inhibits the Chaperone Activity of Plasmodium falciparum Hsp70 Chaperones and Abrogates Their Association with Functional Partners.
Topics: Antimalarials; Binding Sites; Catechin; Cloning, Molecular; Cytosol; Erythrocytes; Escherichia coli; Gene Expression; HSP70 Heat-Shock Proteins; Humans; Inhibitory Concentration 50; Plasmodium falciparum; Protein Binding; Protein Interaction Domains and Motifs; Protein Isoforms; Protein Structure, Secondary; Protein Structure, Tertiary; Protozoan Proteins; Recombinant Proteins | 2017 |
Epigallocatechin-3-gallate inhibits inflammation and epithelial‑mesenchymal transition through the PI3K/AKT pathway via upregulation of PTEN in asthma.
Topics: Airway Remodeling; Animals; Asthma; Catechin; Disease Models, Animal; Epithelial-Mesenchymal Transition; Humans; Inflammation; Mice; Oncogene Protein v-akt; Ovalbumin; Phosphatidylinositol 3-Kinases; PTEN Phosphohydrolase; Signal Transduction; Tea | 2018 |
Intracellular investigation on the differential effects of 4 polyphenols on MCF-7 breast cancer cells by Raman imaging.
Topics: Apoptosis; Breast Neoplasms; Catechin; Cytochromes c; Cytoplasm; Cytosol; Gallic Acid; Humans; Lipid Metabolism; MCF-7 Cells; Polyphenols; Resveratrol; Tannins | 2017 |
Metformin Sensitizes Non-small Cell Lung Cancer Cells to an Epigallocatechin-3-Gallate (EGCG) Treatment by Suppressing the Nrf2/HO-1 Signaling Pathway.
Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line; Cell Line, Tumor; Female; Heme Oxygenase-1; Humans; Lung Neoplasms; Metformin; Mice; Mice, Inbred BALB C; Mice, Nude; NF-E2-Related Factor 2; Promoter Regions, Genetic; Reactive Oxygen Species; Signal Transduction | 2017 |
Effect of epigallocatechin gallate on growth performance and serum biochemical metabolites in heat-stressed broilers.
Topics: Animal Feed; Animals; Antioxidants; Catechin; Chickens; Diet; Dietary Supplements; Hot Temperature; Male; Random Allocation | 2018 |
EGCG-mediated Protection of the Membrane Disruption and Cytotoxicity Caused by the 'Active Oligomer' of α-Synuclein.
Topics: alpha-Synuclein; Amyloid; Animals; Catechin; Cell Membrane; Disease Models, Animal; Drosophila melanogaster; Electrophoresis, Polyacrylamide Gel; Microscopy, Electron, Transmission; Parkinson Disease | 2017 |
Epigallocatechin-3-Gallate Suppresses Human Herpesvirus 8 Replication and Induces ROS Leading to Apoptosis and Autophagy in Primary Effusion Lymphoma Cells.
Topics: Antineoplastic Agents; Antiviral Agents; Apoptosis; Autophagy; Catechin; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; HEK293 Cells; Herpesviridae Infections; Herpesvirus 8, Human; Humans; Lymphoma, Primary Effusion; Reactive Oxygen Species; Virus Replication | 2017 |
Epigallocatechin Gallate-Modified Graphite Paste Electrode for Simultaneous Detection of Redox-Active Biomolecules.
Topics: Ascorbic Acid; Biosensing Techniques; Catechin; Electrochemical Techniques; Electrochemistry; Electrodes; Graphite; Oxidation-Reduction; Uric Acid | 2017 |
Epigallocatechin gallate can attenuate human alveolar epithelial cell injury induced by alpha-haemolysin.
Topics: A549 Cells; Alveolar Epithelial Cells; Bacterial Toxins; Catechin; Cell Line; Hemolysin Proteins; Hemolysis; Humans; Microbial Sensitivity Tests; Protein Multimerization; Staphylococcal Infections; Staphylococcus aureus; Virulence | 2018 |
Effects of (-)-epigallocatechin-3-gallate on EGFR- or Fusion Gene-driven Lung Cancer Cells.
Topics: Anaplastic Lymphoma Kinase; Animals; Blood Proteins; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Crizotinib; Disease Models, Animal; ErbB Receptors; Female; Gene Rearrangement; Heterografts; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Oncogene Proteins, Fusion; Polyphenols; Protein S; Protein-Tyrosine Kinases; Pyrazoles; Pyridines; Receptor Protein-Tyrosine Kinases; Tea | 2017 |
Green Tea Polyphenol EGCG Alleviates Metabolic Abnormality and Fatty Liver by Decreasing Bile Acid and Lipid Absorption in Mice.
Topics: Adipose Tissue; Animals; Bile Acids and Salts; Blood Glucose; Catechin; Fatty Liver; Insulin; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Tea | 2018 |
Effects of (-)-epigallocatechin-3-gallate incorporation on the physicochemical and oxidative stability of myofibrillar protein-soybean oil emulsions.
Topics: Animals; Catechin; Chemical Phenomena; Dose-Response Relationship, Drug; Drug Stability; Emulsions; Hydrophobic and Hydrophilic Interactions; Meat; Muscle Proteins; Oxidation-Reduction; Soybean Oil; Swine | 2018 |
Structural shift of gut microbiota during chemo-preventive effects of epigallocatechin gallate on colorectal carcinogenesis in mice.
Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Carcinogens; Catechin; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Gastrointestinal Microbiome; Humans; Mice; Rectum; RNA, Ribosomal, 16S | 2017 |
Dietary Copper Reduces the Hepatotoxicity of (-)-Epigallocatechin-3-Gallate in Mice.
Topics: Animals; Antioxidants; Catechin; Ceruloplasmin; Chemical and Drug Induced Liver Injury; Copper; Glutathione Peroxidase; Glutathione Reductase; Liver; Male; Malondialdehyde; Mice, Inbred ICR; NADP; Oxidation-Reduction; Tea | 2017 |
Improved anticancer effects of epigallocatechin gallate using RGD-containing nanostructured lipid carriers.
Topics: Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Drug Carriers; Humans; Lipids; Nanoparticles; Oligopeptides | 2018 |
Skin Protective Effect of Epigallocatechin Gallate.
Topics: Animals; Antioxidants; Apoptosis; Caspases; Catechin; Cell Line; Filaggrin Proteins; HEK293 Cells; Humans; Hyaluronan Synthases; Hyaluronoglucosaminidase; Intermediate Filament Proteins; Keratinocytes; Melanins; Mice; Reactive Oxygen Species; Skin; Transglutaminases; Ultraviolet Rays | 2018 |
Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice.
Topics: Amyloid; Amyloidosis; Animals; Biomarkers; Catechin; Humans; Islet Amyloid Polypeptide; Mice; Mice, Transgenic; Models, Molecular; Molecular Conformation; Neuroprotective Agents; Pancreas; Protein Binding | 2018 |
Dynamic cellular maps of molecular species: Application to drug-target interactions.
Topics: Catechin; Drug Discovery; Gene Expression Regulation; HeLa Cells; Humans; Intracellular Space; Microscopy, Fluorescence; Peptide Elongation Factor 1; Protein Binding; Protein Transport | 2018 |
(-)-Epigallocatechin-3-gallate modulates peripheral immunity in the MPTP-induced mouse model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Catechin; Disease Models, Animal; Dopaminergic Neurons; Immunomodulation; Male; Mice; Neuroprotective Agents; Parkinson Disease; T-Lymphocyte Subsets; Tyrosine 3-Monooxygenase | 2018 |
[Isolation and purification of seven catechin compounds from fresh tea leaves by semi-preparative liquid chromatography].
Topics: Catechin; Chromatography, High Pressure Liquid; Gallic Acid; Plant Leaves; Tea | 2017 |
Epigallocatechin-3-gallate confers protection against corticosterone-induced neuron injuries via restoring extracellular signal-regulated kinase 1/2 and phosphatidylinositol-3 kinase/protein kinase B signaling pathways.
Topics: Adenosine Triphosphate; Animals; Catechin; Cells, Cultured; Corticosterone; Hippocampus; MAP Kinase Signaling System; Neurons; Neuroprotective Agents; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Signal Transduction | 2018 |
Protein disulfide isomerases as potential therapeutic targets for influenza A and B viruses.
Topics: A549 Cells; Animals; Antiviral Agents; Catechin; Dogs; Drug Discovery; High-Throughput Screening Assays; Host-Pathogen Interactions; Humans; Influenza A virus; Influenza B virus; Isoenzymes; Madin Darby Canine Kidney Cells; Nitro Compounds; Parabens; Protein Disulfide-Isomerases; Quercetin; RNA, Small Interfering; RNA, Viral; Sesquiterpenes; Thiazoles | 2018 |
The application of pomelo peel as a carrier for adsorption of epigallocatechin-3-gallate.
Topics: Adsorption; Catechin; Citrus; Drug Carriers; Fruit; Hydrogen-Ion Concentration; Kinetics; Microscopy, Electron, Scanning; Plant Extracts; Spectroscopy, Fourier Transform Infrared | 2018 |
Comprehensive Dissection of Metabolic Changes in Albino and Green Tea Cultivars.
Topics: Amino Acids; Camellia sinensis; Catechin; Chlorophyll; Gas Chromatography-Mass Spectrometry; Plant Extracts; Plant Leaves; Sugars | 2018 |
Epigallocatechin-3-gallate attenuates acute and chronic psoriatic itch in mice: Involvement of antioxidant, anti-inflammatory effects and suppression of ERK and Akt signaling pathways.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Antioxidants; Catechin; Chronic Disease; Cytokines; Dose-Response Relationship, Drug; Inflammation Mediators; Male; MAP Kinase Signaling System; Mice; Oncogene Protein v-akt; Pruritus; Reactive Oxygen Species; Skin; Spinal Cord; Treatment Outcome | 2018 |
EGCG Maintains Th1/Th2 Balance and Mitigates Ulcerative Colitis Induced by Dextran Sulfate Sodium through TLR4/MyD88/NF-
Topics: Animals; Catechin; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Intestinal Mucosa; Intestines; Male; Myeloid Differentiation Factor 88; Neuroprotective Agents; NF-kappa B; Rats; Rats, Sprague-Dawley; Signal Transduction; Spleen; Th1-Th2 Balance; Toll-Like Receptor 4 | 2017 |
Biophysical evidence for differential gallated green tea catechins binding to membrane type-1 matrix metalloproteinase and its interactors.
Topics: Carcinogenesis; Catechin; Cell Line, Tumor; Concanavalin A; Endoplasmic Reticulum Chaperone BiP; Enzyme Precursors; Gelatinases; Glioblastoma; Heat-Shock Proteins; Humans; Matrix Metalloproteinase 14; Matrix Metalloproteinase Inhibitors; Protein Binding; Structure-Activity Relationship; Tea | 2018 |
Evaluation of autophagy inducers in epithelial cells carrying the ΔF508 mutation of the cystic fibrosis transmembrane conductance regulator CFTR.
Topics: Autophagy; Bronchi; Catechin; Cell Line; Cell Line, Tumor; Cysteamine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Humans; Transfection | 2018 |
Ameliorative Effect of Epigallocatechin Gallate on Cardiac Hypertrophy and Fibrosis in Aged Rats.
Topics: Age Factors; Aging; Animals; Antioxidants; Apoptosis; Cardiomyopathies; Catechin; Disease Models, Animal; Fibrosis; Hypertrophy, Left Ventricular; Lipids; Myocytes, Cardiac; Oxidative Stress; Rats, Wistar; Reactive Oxygen Species; Signal Transduction; Ventricular Function, Left; Ventricular Remodeling | 2018 |
EGCG evokes Nrf2 nuclear translocation and dampens PTP1B expression to ameliorate metabolic misalignment under insulin resistance condition.
Topics: Active Transport, Cell Nucleus; Animals; Catechin; Heme Oxygenase-1; Humans; Insulin; Insulin Resistance; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Obesity; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Signal Transduction | 2018 |
Regulatory Effects of Neuroinflammatory Responses Through Brain-Derived Neurotrophic Factor Signaling in Microglial Cells.
Topics: Animals; Anti-Inflammatory Agents; Astrocytes; Brain-Derived Neurotrophic Factor; Catechin; Cell Line; Culture Media, Conditioned; Cyclooxygenase 2; Erythropoietin; Hedgehog Proteins; Humans; Inflammation; Inflammation Mediators; Lipopolysaccharides; Mice; Microglia; Minocycline; Models, Biological; Neuroprotective Agents; Signal Transduction | 2018 |
Profiling cytokine levels in chlorhexidine and EGCG-treated odontoblast-like cells.
Topics: Animals; Catechin; Cell Line; Chlorhexidine; Cytokines; Mice; Odontoblasts | 2018 |
Inhibitory effect of the green tea molecule EGCG against dengue virus infection.
Topics: Antiviral Agents; Catechin; Dengue Virus; Dose-Response Relationship, Drug; Encephalitis Virus, Japanese; Species Specificity; Tea; Virion; Virus Internalization; Yellow fever virus; Zika Virus | 2018 |
"Stealth and Fully-Laden" Drug Carriers: Self-Assembled Nanogels Encapsulated with Epigallocatechin Gallate and siRNA for Drug-Resistant Breast Cancer Therapy.
Topics: Animals; Breast Neoplasms; Catechin; Cell Line, Tumor; Drug Carriers; Mice; Nanoparticles; RNA, Small Interfering | 2018 |
Epigallocatechin gallate suppresses hepatic cholesterol synthesis by targeting SREBP-2 through SIRT1/FOXO1 signaling pathway.
Topics: Animals; Catechin; Cholesterol; Hypercholesterolemia; Liver; Male; Mice; Nerve Tissue Proteins; Rats; Rats, Wistar; Signal Transduction; Sirtuin 1; Sterol Regulatory Element Binding Protein 2 | 2018 |
Epigallocatechin Gallate Reduces Amyloid β-Induced Neurotoxicity via Inhibiting Endoplasmic Reticulum Stress-Mediated Apoptosis.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Caspase 12; Caspase 3; Catechin; Cell Line, Tumor; Cell Survival; Cerebral Cortex; Dietary Supplements; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Humans; Mice, Transgenic; Microscopy, Electron, Transmission; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nootropic Agents; Peptide Fragments; Random Allocation; Transcription Factor CHOP | 2018 |
Molecular insights on the interaction and preventive potential of epigallocatechin-3-gallate in Celiac Disease.
Topics: Caco-2 Cells; Calorimetry; Catechin; Celiac Disease; Humans; Molecular Conformation; Molecular Dynamics Simulation; Peptides; Proton Magnetic Resonance Spectroscopy; Tannins; Thermodynamics | 2018 |
Effects of fluoride and epigallocatechin gallate on soft-drink-induced dental erosion of enamel and root dentin.
Topics: Carbonated Beverages; Catechin; Dental Enamel; Dentin; Humans; Microscopy, Electron, Scanning; Sodium Fluoride; Tooth Erosion; Tooth Root | 2018 |
Epigallocatechin-3-gallate loaded PEGylated-PLGA nanoparticles: A new anti-seizure strategy for temporal lobe epilepsy.
Topics: Animals; Catechin; Drug Carriers; Emulsions; Epilepsy, Temporal Lobe; Mice; Mice, Inbred C57BL; Nanoparticles; Particle Size; PC12 Cells; Polyethylene Glycols; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Seizures | 2018 |
Liposomal Formulations for an Efficient Encapsulation of Epigallocatechin-3-gallate: An in- Silico/Experimental Approach.
Topics: Antioxidants; Calcium; Catechin; Drug Delivery Systems; Lipid Bilayers; Lipids; Liposomes; Magnesium; Particle Size | 2018 |
GPCR6A Is a Molecular Target for the Natural Products Gallate and EGCG in Green Tea.
Topics: Animals; Binding Sites; Catechin; Cells, Cultured; Computational Biology; Dietary Supplements; Gallic Acid; Gene Expression Regulation; HEK293 Cells; Humans; Incretins; Insulin Secretion; Kidney; MAP Kinase Signaling System; Mice; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Receptors, G-Protein-Coupled; Recombinant Proteins; RNA Interference; Tea | 2018 |
Nanogels of dual inhibitor-modified hyaluronic acid function as a potent inhibitor of amyloid β-protein aggregation and cytotoxicity.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Catechin; Cell Line; Cell Proliferation; Cell Survival; Humans; Hyaluronic Acid; Hydrogels; Hydrophobic and Hydrophilic Interactions; Nanoparticles; Polyethylene Glycols; Protein Aggregates | 2018 |
Epigallocatechin Gallate Reduces Ischemia/Reperfusion Injury in Isolated Perfused Rabbit Hearts.
Topics: Animals; Apoptosis Inducing Factor; Blood Pressure; Catechin; Heart; Heart Ventricles; Hemodynamics; Hypoxia-Inducible Factor 1, alpha Subunit; Myocardial Contraction; Myocardial Reperfusion Injury; Perfusion; Rabbits; Staining and Labeling | 2018 |
GREEN TEA BEVERAGE AND EPIGALLOCATECIHIN GALLATE ATTENUATE NICOTINE CARDIOCYTOTOXICITY IN RAT.
Topics: Animals; Cardiotoxicity; Catechin; Endoplasmic Reticulum Stress; Extracellular Signal-Regulated MAP Kinases; Lipid Peroxidation; Male; Nicotine; Oxidative Stress; Plant Extracts; Rats; Tea; Transcription Factor CHOP | 2017 |
SOX2OT variant 7 contributes to the synergistic interaction between EGCG and Doxorubicin to kill osteosarcoma via autophagy and stemness inhibition.
Topics: Animals; Apoptosis; Autophagy; Biomarkers; Bone Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Self Renewal; Disease Models, Animal; Doxorubicin; Gene Expression; Humans; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Neoplastic Stem Cells; Osteosarcoma; Receptor, Notch3; RNA, Long Noncoding; Xenograft Model Antitumor Assays | 2018 |
Green tea supplementation upregulates uncoupling protein 3 expression in severe obese women adipose tissue but does not promote weight loss.
Topics: Adipose Tissue; Adolescent; Adult; Basal Metabolism; Body Mass Index; Catechin; Dietary Supplements; Humans; Longitudinal Studies; Middle Aged; Obesity; Perilipin-1; Plant Extracts; PPAR gamma; Receptors, Adrenergic, beta-3; Tea; Uncoupling Protein 1; Uncoupling Protein 3; Up-Regulation; Weight Loss; Young Adult | 2018 |
The Effects of Green Tea Extract on Working Memory in Healthy Women.
Topics: Adult; Antioxidants; Catechin; Female; Humans; Malondialdehyde; Memory, Short-Term; Plant Extracts; Single-Blind Method; Tea; Women's Health; Young Adult | 2018 |
Dual-effect liposomes with increased antitumor effects against 67-kDa laminin receptor-overexpressing tumor cells.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Line, Tumor; Doxorubicin; Humans; Liposomes; Male; Mice; Mice, Inbred C57BL; Polyethylene Glycols; Receptors, Laminin; Tissue Distribution; Topoisomerase II Inhibitors; Xenograft Model Antitumor Assays | 2018 |
Mechanisms of astringency: Structural alteration of the oral mucosal pellicle by dietary tannins and protective effect of bPRPs.
Topics: Astringents; Catechin; Cell Line; Dental Pellicle; Diet; Humans; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Mouth Mucosa; Mucin-5B; Protein Aggregates; Saliva; Salivary Proline-Rich Proteins; Tannins | 2018 |
Structural Modification of (-)-Epigallocatechin Gallate (EGCG) Shows Significant Enhancement in Mitochondrial Biogenesis.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Catechin; Cell Line; Cytochromes c; Humans; Mitochondria; Organelle Biogenesis; Oxidative Phosphorylation; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Kinases | 2018 |
Sinecatechins ointment 10% (Veregen®) for genital warts: percutaneous penetration of epigallocatechin gallate concentrations in the stratum corneum collected by adhesive tape stripping method.
Topics: Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Condylomata Acuminata; Epidermis; Half-Life; Humans; Ointments | 2018 |
Effects of Supplemental Epigallocatechin Gallate in the Diet of Broilers Exposed to Fluoride Intoxication.
Topics: Animal Feed; Animals; Antioxidants; Catechin; Chickens; Dietary Supplements; Fluoride Poisoning; Fluorides; Liver; Male | 2018 |
Epigallocatechin-3-gallate improves cardiac hypertrophy and short-term memory deficits in a Williams-Beuren syndrome mouse model.
Topics: Animals; Cardiomegaly; Catechin; Disease Models, Animal; Memory Disorders; Memory, Short-Term; Mice; Mice, Mutant Strains; Williams Syndrome | 2018 |
Punicalagin and (-)-Epigallocatechin-3-Gallate Rescue Cell Viability and Attenuate Inflammatory Responses of Human Epidermal Keratinocytes Exposed to Airborne Particulate Matter PM10.
Topics: Antioxidants; Catechin; Cell Survival; Cells, Cultured; Cytokines; Humans; Hydrolyzable Tannins; Inflammation; Keratinocytes; Particulate Matter; Reactive Oxygen Species | 2018 |
Epigallocatechin-3-gallate partially restored redox homeostasis in arsenite-stressed keratinocytes.
Topics: Antioxidants; Arsenites; Catechin; Cell Line; Cell Survival; DNA Damage; Homeostasis; Humans; Keratinocytes; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species | 2018 |
Flavan-3-ol/Procyanidin Metabolomics in Rat Urine Using HPLC-Quadrupole TOF/MS.
Topics: Animals; Biflavonoids; Catechin; Chromatography, High Pressure Liquid; Flavonoids; Male; Mass Spectrometry; Molecular Weight; Proanthocyanidins; Rats, Wistar | 2018 |
Epigallocatechin gallate & curcumin prevent transforming growth factor beta 1-induced epithelial to mesenchymal transition in ARPE-19 cells.
Topics: Catechin; Cell Movement; Cell Proliferation; Curcumin; Epithelial Cells; Epithelial-Mesenchymal Transition; Humans; Matrix Metalloproteinase 2; Phosphorylation; Retinal Pigment Epithelium; Smad3 Protein; Transforming Growth Factor beta1; Vitreoretinopathy, Proliferative | 2017 |
Application of metabolomics profiling in the analysis of metabolites and taste quality in different subtypes of white tea.
Topics: Amino Acids; Astringents; Benzopyrans; Biflavonoids; Caffeine; Catechin; Flavones; Flavonoids; Flavonols; Gallic Acid; Glycosides; Hydroxybenzoates; Metabolomics; Odorants; Phenols; Plant Extracts; Polyphenols; Proanthocyanidins; Quinic Acid; Taste; Tea | 2018 |
Epigallocatechin-3-Gallate-Rich Green Tea Extract Ameliorates Fatty Liver and Weight Gain in Mice Fed a High Fat Diet by Activating the Sirtuin 1 and AMP Activating Protein Kinase Pathway.
Topics: Animals; Catechin; Cell Survival; Diet, High-Fat; Fatty Liver; Hep G2 Cells; Humans; Hyperglycemia; Hypertriglyceridemia; Insulin Resistance; Male; MAP Kinase Signaling System; Mice, Inbred C57BL; Obesity; Phytotherapy; Plant Extracts; Sirtuin 1; Tea; Weight Gain | 2018 |
Differences in the Effects of EGCG on Chromosomal Stability and Cell Growth between Normal and Colon Cancer Cells.
Topics: Apoptosis; Catechin; Cell Line, Tumor; Chromosomal Instability; Colonic Neoplasms; DNA Mismatch Repair; Humans; Tea | 2018 |
Immuno-modulators enhance antigen-specific immunity and anti-tumor effects of mesothelin-specific chimeric DNA vaccine through promoting DC maturation.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Cancer Vaccines; Catechin; Cell Line, Tumor; Connective Tissue Growth Factor; Dendritic Cells; Drug Synergism; Female; GPI-Linked Proteins; Lung Neoplasms; Mesothelin; Mesothelioma; Mesothelioma, Malignant; Mice; Poly I-C; Treatment Outcome; Vaccines, DNA; Xenograft Model Antitumor Assays | 2018 |
Epigallocatechin-3-gallate alleviates bladder overactivity in a rat model with metabolic syndrome and ovarian hormone deficiency through mitochondria apoptosis pathways.
Topics: Animals; Apoptosis; Biomarkers; Catechin; Diet, Carbohydrate Loading; Diet, High-Fat; Disease Models, Animal; Female; Metabolic Syndrome; Mitochondria; Ovariectomy; Oxidative Stress; Plant Extracts; Primary Ovarian Insufficiency; Rats; Rats, Sprague-Dawley; Tea; Urinary Bladder, Overactive | 2018 |
Molecular determinants of the interaction of EGCG with ordered and disordered proteins.
Topics: alpha-Synuclein; Catechin; Humans; Intrinsically Disordered Proteins; Muramidase; Protein Binding | 2018 |
Herpes simplex virus virucidal activity of MST-312 and epigallocatechin gallate.
Topics: Animals; Antiviral Agents; Benzamides; Catechin; Chlorocebus aethiops; Herpesvirus 1, Human; Microbial Sensitivity Tests; Microbial Viability; Temperature; Time Factors; Vero Cells; Viral Plaque Assay | 2018 |
Reducing the allergenic capacity of β-lactoglobulin by covalent conjugation with dietary polyphenols.
Topics: Allergens; Animals; Catechin; Cattle; Chlorogenic Acid; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Lactoglobulins; Polyphenols; Spectrometry, Fluorescence | 2018 |
Inhibitory Effect of (-)-Epigallocatechin-3-O-gallate on Octanoylated Ghrelin Levels in Vitro and in Vivo.
Topics: Acyltransferases; Animals; Anti-Obesity Agents; Caprylates; Catechin; Cell Line, Tumor; Furin; Ghrelin; Humans; Male; Mice, Inbred C57BL; RNA, Messenger | 2018 |
Glucose-regulated protein 78 substrate-binding domain alters its conformation upon EGCG inhibitor binding to nucleotide-binding domain: Molecular dynamics studies.
Topics: Catechin; Heat-Shock Proteins; Hydrogen Bonding; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Binding; Protein Domains; Protein Folding | 2018 |
Impact of epigallocatechin‑3‑gallate on expression of nuclear factor erythroid 2‑related factor 2 and γ‑glutamyl cysteine synthetase genes in oxidative stress‑induced mouse renal tubular epithelial cells.
Topics: Animals; Apoptosis; Catechin; Cell Survival; Epithelial Cells; Glutamate-Cysteine Ligase; Immunohistochemistry; Kidney Tubules; Mice; NF-E2-Related Factor 2; Oxidative Stress | 2018 |
Epigallocatechingallate attenuates myocardial injury in a mouse model of heart failure through TGF‑β1/Smad3 signaling pathway.
Topics: Animals; Apoptosis; Biomarkers; Catechin; Cytokines; Disease Models, Animal; Fibrosis; Heart Failure; Inflammation Mediators; Male; Mice; Myocardium; Oxidative Stress; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1; Ultrasonography | 2018 |
The relative antioxidant activity and steric structure of green tea catechins - A kinetic approach.
Topics: Antioxidants; Catechin; Chromatography, High Pressure Liquid; Kinetics; Mass Spectrometry; Stereoisomerism; Tea | 2018 |
Green tea polyphenols enhance gingival keratinocyte integrity and protect against invasion by Porphyromonas gingivalis.
Topics: Adhesins, Bacterial; Anti-Bacterial Agents; Bacterial Translocation; Catechin; Cell Line, Transformed; Cysteine Endopeptidases; Dextrans; Electric Impedance; Enzyme Assays; Fluorescein-5-isothiocyanate; Gene Expression Regulation; Gingipain Cysteine Endopeptidases; Gingiva; Humans; Keratinocytes; Models, Biological; Occludin; Porphyromonas gingivalis; Tea; Zonula Occludens-1 Protein | 2018 |
Epigallocatechin-3-Gallate (EGCG) Promotes Autophagy-Dependent Survival via Influencing the Balance of mTOR-AMPK Pathways upon Endoplasmic Reticulum Stress.
Topics: Autophagy; Catechin; Cell Survival; Endoplasmic Reticulum Stress; Humans; Tea; TOR Serine-Threonine Kinases | 2018 |
Epigallocatechin Gallate-Modified Gelatin Sponges Treated by Vacuum Heating as a Novel Scaffold for Bone Tissue Engineering.
Topics: Animals; Bone Regeneration; Catechin; Cell Line; Cell Proliferation; Gelatin; Heating; Osteoblasts; Rats; Regenerative Medicine; Skull; Tissue Engineering; Tissue Scaffolds; Vacuum; X-Ray Microtomography | 2018 |
Quantitative analyses of the bitterness and astringency of catechins from green tea.
Topics: Astringents; Aversive Agents; Catechin; Flavonols; Taste Perception; Tea | 2018 |
Epigallocatechin-3-gallate protects Kuruma shrimp Marsupeneaus japonicus from white spot syndrome virus and Vibrio alginolyticus.
Topics: Animals; Anti-Bacterial Agents; Antiviral Agents; Catechin; Immunity, Innate; Penaeidae; Protective Agents; Random Allocation; Vibrio alginolyticus; White spot syndrome virus 1 | 2018 |
The effect of tea consumption on the steroid profile.
Topics: Adult; Androsterone; Catechin; Doping in Sports; Gas Chromatography-Mass Spectrometry; Glucuronides; Healthy Volunteers; Humans; Indicators and Reagents; Male; Steroids; Tea; Testosterone; Young Adult | 2018 |
Epigallocatechin-3-Gallate Protects and Prevents Paraquat-Induced Oxidative Stress and Neurodegeneration in Knockdown dj-1-β Drosophila melanogaster.
Topics: Animals; Animals, Genetically Modified; Antioxidants; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Drosophila melanogaster; Drosophila Proteins; Female; Herbicides; Lipid Peroxidation; Locomotion; Male; Minocycline; Nerve Tissue Proteins; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Paraquat; Protein Deglycase DJ-1; Tyrosine 3-Monooxygenase | 2018 |
Effects of noble metal nanoparticles on the hydroxyl radical scavenging ability of dietary antioxidants.
Topics: Antioxidants; Ascorbic Acid; Catechin; Dietary Supplements; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Gallic Acid; Gold; Hydroxyl Radical; Metal Nanoparticles; Palladium; Platinum; Silver | 2018 |
Epigallocatechin-3-gallate attenuates microcystin-LR-induced apoptosis in human umbilical vein endothelial cells through activation of the NRF2/HO-1 pathway.
Topics: Antioxidants; Apoptosis; Caspase 3; Catechin; Cytochromes c; Gene Expression Regulation; Heme Oxygenase-1; Human Umbilical Vein Endothelial Cells; Humans; Marine Toxins; Membrane Potential, Mitochondrial; Microcystins; Mitochondria; NF-E2-Related Factor 2; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Signal Transduction | 2018 |
Evidence of similar protective effects afforded by white tea and its active component 'EGCG' on oxidative-stress mediated hepatic dysfunction during benzo(a)pyrene induced toxicity.
Topics: Animals; Antioxidants; Benzo(a)pyrene; Biomarkers; Body Weight; Catechin; Chemical and Drug Induced Liver Injury; Female; Liver; Oxidative Stress; Rats, Sprague-Dawley; Tea | 2018 |
Epigallocatechin gallate inhibits the proliferation and induces apoptosis of multiple myeloma cells via inactivating EZH2.
Topics: Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Humans; Mitochondria; Multiple Myeloma; Proto-Oncogene Proteins c-bcl-2; Tea | 2018 |
Quantitative Analysis of Four Catechins from Green Tea Extract in Human Plasma Using Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry for Pharmacokinetic Studies.
Topics: Catechin; Chromatography, High Pressure Liquid; Humans; Reproducibility of Results; Tandem Mass Spectrometry; Tea | 2018 |
Macrophage phenotype in the epigallocatechin-3-gallate (EGCG)-modified collagen determines foreign body reaction.
Topics: Animals; Catechin; Cattle; Chemokines; Collagen; Foreign-Body Reaction; Gene Expression Regulation; Macrophages; Male; Neovascularization, Physiologic; Neutrophils; Phenotype; Rats, Sprague-Dawley | 2018 |
Target challenging-cancer drug delivery to gastric cancer tissues with a fucose graft epigallocatechin-3-gallate-gold particles nanocomposite approach.
Topics: Animals; Antineoplastic Agents; Catechin; Cell Line, Tumor; Chitosan; Drug Carriers; Fucose; Gold; Helicobacter pylori; Humans; Kidney; Liver; Metal Nanoparticles; Mice; Microscopy, Electron, Transmission; Nanocomposites; Particle Size; Spectroscopy, Fourier Transform Infrared; Stomach Neoplasms; Transplantation, Heterologous; X-Ray Diffraction | 2018 |
Honokiol nanoparticles based on epigallocatechin gallate functionalized chitin to enhance therapeutic effects against liver cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biphenyl Compounds; Carcinoma, Hepatocellular; Catechin; Cell Proliferation; Chitin; Cross-Linking Reagents; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Liberation; G2 Phase Cell Cycle Checkpoints; Hep G2 Cells; Humans; Kinetics; Lignans; Liver Neoplasms; Male; Membrane Potential, Mitochondrial; Mice, Inbred BALB C; Nanoparticles; Nanotechnology; Particle Size; Solubility; Surface Properties; Technology, Pharmaceutical; Tumor Burden; Xenograft Model Antitumor Assays | 2018 |
Epigallocatechin-3-Gallate Regulates Anti-Inflammatory Action Through 67-kDa Laminin Receptor-Mediated Tollip Signaling Induction in Lipopolysaccharide-Stimulated Human Intestinal Epithelial Cells.
Topics: Anti-Inflammatory Agents; Catechin; HT29 Cells; Humans; Intestinal Mucosa; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Receptors, Laminin; Signal Transduction | 2018 |
Human insulin fibrillogenesis in the presence of epigallocatechin gallate and melatonin: Structural insights from a biophysical approach.
Topics: Amino Acid Sequence; Catechin; Humans; Insulin; Melatonin; Molecular Dynamics Simulation; Protein Conformation, beta-Strand; Protein Multimerization | 2018 |
Enterodiol is Actively Transported by Rat Liver Cell Membranes.
Topics: Adenosine Triphosphatases; Animals; Catechin; Cell Membrane; Hydrophobic and Hydrophilic Interactions; Lignans; Lipid Bilayers; Liver; Polyphenols; Rats | 2018 |
Epigallocatechin gallate inhibits corneal neovascularization in ratalkaline burn model.
Topics: Animals; Burns, Chemical; Catechin; Corneal Neovascularization; Eye Proteins; Inflammation; Male; Neoplasm Proteins; Nerve Growth Factors; Nucleocytoplasmic Transport Proteins; Rats; Serpins; Sodium Hydroxide; Time Factors; Vascular Endothelial Growth Factor A | 2018 |
Nano-encapsulation of epigallocatechin gallate in the ferritin-chitosan double shells: Simulated digestion and absorption evaluation.
Topics: Caco-2 Cells; Catechin; Chitosan; Digestion; Electrophoresis, Polyacrylamide Gel; Ferritins; Gastric Juice; Humans; Intestinal Absorption; Intestinal Secretions; Microscopy, Electron, Transmission; Nanoparticles; Nanotechnology; Pepsin A; Spectrometry, Fluorescence; Static Electricity; Trypsin | 2018 |
Inhibition of interaction between epigallocatechin-3-gallate and myofibrillar protein by cyclodextrin derivatives improves gel quality under oxidative stress.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Antioxidants; beta-Cyclodextrins; Catechin; Cooking; Emulsions; Gels; Hot Temperature; Meat Proteins; Myofibrils; Oxidation-Reduction; Oxidative Stress; Protein Binding; Protein Carbonylation; Protein Conformation; Protein Unfolding; Red Meat; Solubility; Sus scrofa; Viscosity | 2018 |
Covalent modification of soy protein isolate by (-)-epigallocatechin-3-gallate: effects on structural and emulsifying properties.
Topics: Catechin; Circular Dichroism; Emulsions; Hydrophobic and Hydrophilic Interactions; Protein Conformation, alpha-Helical; Soybean Proteins | 2018 |
Quantification of ascorbyl adducts of epigallocatechin gallate and gallocatechin gallate in bottled tea beverages.
Topics: Camellia sinensis; Catechin; Dehydroascorbic Acid; Molecular Structure; Tea | 2018 |
(-)- Epigallocatechin-3-gallate induces GRP78 accumulation in the ER and shifts mesothelioma constitutive UPR into proapoptotic ER stress.
Topics: Apoptosis; Catechin; Cell Survival; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Homeostasis; Humans; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Molecular Chaperones | 2018 |
(-)-Epigallocatechin 3-Gallate Synthetic Analogues Inhibit Fatty Acid Synthase and Show Anticancer Activity in Triple Negative Breast Cancer.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Fatty Acid Synthases; Female; Humans; Molecular Structure; Triple Negative Breast Neoplasms | 2018 |
Cytoprotective Effect of Epigallocatechin Gallate (EGCG)-5'-O-α-Glucopyranoside, a Novel EGCG Derivative.
Topics: Apoptosis; Catechin; Cell Line; Cell Proliferation; Free Radical Scavengers; Glucosides; HEK293 Cells; Humans; Nitric Oxide; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Radiation-Protective Agents; Reactive Oxygen Species | 2018 |
Epigallocatechin-3-Gallate Reduces Neuronal Apoptosis in Rats after Middle Cerebral Artery Occlusion Injury via PI3K/AKT/eNOS Signaling Pathway.
Topics: Animals; Apoptosis; Brain Ischemia; Catechin; Chromones; Infarction, Middle Cerebral Artery; Male; Morpholines; Neuroprotective Agents; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction | 2018 |
Paradoxical cardiotoxicity of intraperitoneally-injected epigallocatechin gallate preparation in diabetic mice.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Catechin; Creatine Kinase, MB Form; Diabetes Mellitus, Experimental; Electrocardiography; Heart; HSP90 Heat-Shock Proteins; Injections, Intraperitoneal; Male; Mice; Myocardium; NADPH Oxidases; NF-kappa B; Oxidative Stress; Troponin I | 2018 |
Subtype-selective inhibition of acid-sensing ion channel 3 by a natural flavonoid.
Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Analgesics; Animals; Catechin; CHO Cells; Cricetulus; Humans; Male; Mice, Inbred C57BL; Molecular Structure; Pain; Random Allocation; Rats; Structure-Activity Relationship | 2019 |
Targeting of EGFR, VEGFR2, and Akt by Engineered Dual Drug Encapsulated Mesoporous Silica-Gold Nanoclusters Sensitizes Tamoxifen-Resistant Breast Cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Chemical Engineering; Drug Carriers; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gold; Humans; Metal Nanoparticles; Mice, Nude; Piperidines; Porosity; Proto-Oncogene Proteins c-akt; Quinazolines; Silicon Dioxide; Tamoxifen; Treatment Outcome; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2018 |
Epigallocatechin-3-gallate protected vanadium-induced eggshell depigmentation via P38MAPK-Nrf2/HO-1 signaling pathway in laying hens.
Topics: Animal Feed; Animals; Antioxidants; Avian Proteins; Catechin; Chickens; Diet; Dietary Supplements; Egg Shell; Female; Pigmentation; Random Allocation; Signal Transduction; Vanadium | 2018 |
Epigallocatechin gallate targets FTO and inhibits adipogenesis in an mRNA m
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Anti-Obesity Agents; Catechin; Disease Models, Animal; Mice; RNA-Binding Proteins; RNA, Messenger; Tea | 2018 |
Dentin bonding and physicochemical properties of adhesives incorporated with epigallocatechin-3-gallate.
Topics: Acid Etching, Dental; Catechin; Dental Bonding; Dentin-Bonding Agents; Flexural Strength; Humans; In Vitro Techniques; Materials Testing; Molar; Polymerization; Surface Properties; Tensile Strength | 2019 |
Combined effects of resveratrol and epigallocatechin-3-gallate on post thaw boar sperm and IVF parameters.
Topics: Animals; Catechin; Fertilization in Vitro; Male; Resveratrol; Semen Analysis; Spermatozoa; Stilbenes; Swine | 2018 |
Inhibition of Al(III)-Induced A
Topics: Aluminum; Amyloid beta-Peptides; Catechin; Nanoparticles; Peptide Fragments | 2018 |
Active compounds and derivatives of camellia sinensis responding to erosive attacks on dentin.
Topics: Biflavonoids; Camellia sinensis; Catechin; Dentin; Fluorides; Gallic Acid; Humans; Tea; Tooth Erosion; Water | 2018 |
Epigallocatechin-3-gallate remodels apolipoprotein A-I amyloid fibrils into soluble oligomers in the presence of heparin.
Topics: Amyloid; Apolipoprotein A-I; Catechin; Heparin; Humans; Magnetic Resonance Spectroscopy; Protein Structure, Secondary | 2018 |
Inhibitory effects of Myricetin derivatives on curli-dependent biofilm formation in Escherichia coli.
Topics: Bacterial Proteins; Biofilms; Catechin; Escherichia coli; Flavonoids; Gene Expression Regulation, Bacterial; Sigma Factor | 2018 |
Epigallocatechin-3-gallate local pre-exposure application prevents SHIV rectal infection of macaques.
Topics: Animals; Antiviral Agents; Catechin; CD4 Antigens; Cell Movement; Disease Transmission, Infectious; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Macaca; Macrophages; Protein Binding; Risk; Sexually Transmitted Diseases, Viral; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tea | 2018 |
Identification of Estrogen Receptor
Topics: Bayes Theorem; Binding Sites; Biological Products; Breast Neoplasms; Catechin; Databases, Factual; Estrogen Receptor alpha; Female; Genistein; Humans; Inhibitory Concentration 50; Ligands; Machine Learning; MCF-7 Cells; Molecular Docking Simulation; Protein Binding | 2018 |
Green tea polyphenol epigallocatechin-3-gallate increases atherosclerotic plaque stability in apolipoprotein E-deficient mice fed a high-fat diet.
Topics: Animals; Apolipoproteins E; Basigin; Catechin; Cytokines; Diet, High-Fat; Gene Expression Regulation; Inflammation; Macrophages; Male; Matrix Metalloproteinases; Mice; Mice, Transgenic; Myocytes, Smooth Muscle; Plaque, Atherosclerotic; Tea | 2018 |
Chiral Recognition of Pharmaceuticals Having a Xanthine Skeleton by (-)-Epigallocatechin-3-O-gallate in Water.
Topics: Catechin; Molecular Structure; Pharmaceutical Preparations; Stereoisomerism; Water; Xanthine | 2018 |
Leishmanicidal activity of green tea leaves and pomegranate peel extracts on
Topics: Antiparasitic Agents; Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fruit; Leishmania infantum; Magnetic Resonance Spectroscopy; Plant Extracts; Plant Leaves; Pomegranate | 2019 |
EGCG stimulates the recruitment of brite adipocytes, suppresses adipogenesis and counteracts TNF-α-triggered insulin resistance in adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipocytes, Beige; Adipogenesis; Animals; Catechin; Insulin Resistance; Mice; Obesity; Oxidative Stress; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Uncoupling Protein 1 | 2018 |
SAXS characterization of the interactions among digested food compounds and the anti-oxidant and anti-inflammatory activities of the formed nanocomplexes.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Caseins; Catechin; Chitosan; Hydrogen Peroxide; Interleukin-1beta; Macrophages; Mice; Nanoparticles; NF-kappa B; Nitric Oxide; Particle Size; Phosphopeptides; RAW 264.7 Cells; Scattering, Small Angle | 2018 |
Epigallocatechin-3-gallate tolerability and impact on survival in a cohort of patients with transthyretin-related cardiac amyloidosis. A single-center retrospective study.
Topics: Amyloid Neuropathies, Familial; Case-Control Studies; Catechin; Cohort Studies; Female; Humans; Italy; Male; Neuroprotective Agents; Retrospective Studies; Treatment Outcome | 2018 |
Oxidative stability and in vitro digestion of menhaden oil emulsions with whey protein: Effects of EGCG conjugation and interfacial cross-linking.
Topics: Antioxidants; Catechin; Circular Dichroism; Digestion; Electrophoresis, Polyacrylamide Gel; Emulsions; Fish Oils; Iridoids; Lipolysis; Oxidation-Reduction; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Whey Proteins | 2018 |
Impact of the green tea ingredient epigallocatechin gallate and a short pentapeptide (Ile-Ile-Ala-Glu-Lys) on the structural organization of mixed micelles and the related uptake of cholesterol.
Topics: Catechin; Cholesterol; Humans; Micelles; Peptide Fragments; Tea | 2018 |
[Determination of 8 components in healthy food for anti-hangover and hepatoprotection by high performance liquid chromatography].
Topics: Catechin; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Flavonols; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Sensitivity and Specificity | 2017 |
Interactions of quercetin, curcumin, epigallocatechin gallate and folic acid with gelatin.
Topics: Binding Sites; Catechin; Circular Dichroism; Curcumin; Folic Acid; Gelatin; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Protein Binding; Protein Structure, Secondary; Quercetin; Spectrometry, Fluorescence; Thermodynamics | 2018 |
Epigallocatechin gallate improves airway inflammation through TGF‑β1 signaling pathway in asthmatic mice.
Topics: Animals; Asthma; Catechin; Cytokines; Inflammation; Male; Mice; Mice, Inbred BALB C; Signal Transduction; Smad2 Protein; Smad3 Protein; T-Lymphocytes, Regulatory; Th17 Cells; Transforming Growth Factor beta1 | 2018 |
Efficient α-Glucosylation of Epigallocatechin Gallate Catalyzed by Cyclodextrin Glucanotransferase from Thermoanaerobacter Species.
Topics: Bacterial Proteins; Biocatalysis; Catechin; Chromatography, High Pressure Liquid; Glucosyltransferases; Glycosylation; Mass Spectrometry; Thermoanaerobacter | 2018 |
Epigallocatechin gallate improves insulin resistance in HepG2 cells through alleviating inflammation and lipotoxicity.
Topics: Animals; Catechin; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Hep G2 Cells; Humans; Inflammation; Insulin Resistance; Oxidative Stress; Rats; Transfection | 2018 |
Epigallocatechin-3-gallate reduces damage to osteoblast-like cells treated with Zoledronic acid.
Topics: Calcification, Physiologic; Catechin; Cell Culture Techniques; Cell Line; Cell Movement; Cell Survival; Collagen; Dose-Response Relationship, Drug; Humans; Osteoblasts; Wound Healing; Zoledronic Acid | 2018 |
Epigallocatechin-3-gallate inhibits the early stages of Japanese encephalitis virus infection.
Topics: Antiviral Agents; Catechin; Cell Line; Cytopathogenic Effect, Viral; Encephalitis Virus, Japanese; Encephalitis, Japanese; Humans; Virus Attachment; Virus Internalization; Virus Replication | 2018 |
Tas2r125 functions as the main receptor for detecting bitterness of tea catechins in the oral cavity of mice.
Topics: Animals; Avoidance Learning; Catechin; Mice; Mouth; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Taste; Tea | 2018 |
Saturated fatty acid attenuates anti-obesity effect of green tea.
Topics: Adipose Tissue, White; Animals; Catechin; Diet, High-Fat; Fatty Acids; Male; Meat; Mice; Mice, Inbred C57BL; Obesity; Olive Oil; Plant Extracts; PPAR gamma; Tea; Weight Gain | 2018 |
Green tea supplementation promotes leukocyte telomere length elongation in obese women.
Topics: Adult; Body Mass Index; Catechin; Cross-Sectional Studies; Dietary Supplements; Female; Humans; Leukocytes; Middle Aged; Obesity; Tea; Telomere; Telomere Shortening | 2018 |
Inhibition of Epigallocatechin-3-gallate/Protein Interaction by Methyl-β-cyclodextrin in Myofibrillar Protein Emulsion Gels under Oxidative Stress.
Topics: Animals; beta-Cyclodextrins; Catechin; Emulsions; Hydrophobic and Hydrophilic Interactions; Muscle Proteins; Myofibrils; Oxidation-Reduction; Polyphenols; Protein Binding; Solubility; Swine | 2018 |
Inhibitory effects of tea catechin epigallocatechin-3-gallate against biofilms formed from Streptococcus mutans and a probiotic lactobacillus strain.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Biomass; Catechin; Dose-Response Relationship, Drug; Gene Expression Regulation, Bacterial; Glucosyltransferases; Lacticaseibacillus casei; Microbial Sensitivity Tests; Microbial Viability; Polysaccharides; Probiotics; Streptococcus mutans; Tea | 2018 |
Epigallocatechin gallate induces GLUT4 translocation in skeletal muscle through both PI3K- and AMPK-dependent pathways.
Topics: AMP-Activated Protein Kinases; Animals; Catechin; Cell Line; Cell Membrane; Gene Expression Regulation; Glucose; Glucose Transporter Type 4; Insulin; Isoenzymes; Male; Mice; Mice, Inbred ICR; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Protein Transport | 2018 |
Chemopreventive effect of sulindac in combination with epigallocatechin gallate or kaempferol against 1,2-dimethyl hydrazine-induced preneoplastic lesions in rats: A Comparative Study.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; beta Catenin; Carcinogens; Catechin; Colonic Neoplasms; Cyclooxygenase 2; Down-Regulation; Drug Therapy, Combination; Kaempferols; Male; Nitric Oxide; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats, Sprague-Dawley; Sulindac; Thiobarbituric Acid Reactive Substances | 2018 |
(-)-Epigallocatechin gallate derivatives reduce the expression of both urokinase plasminogen activator and plasminogen activator inhibitor-1 to inhibit migration, adhesion, and invasion of MDA-MB-231 cells.
Topics: Breast Neoplasms; Catechin; Cell Adhesion; Cell Line, Tumor; Cell Movement; Female; Humans; Neoplasm Invasiveness; Plasminogen; Plasminogen Activator Inhibitor 1; Signal Transduction; Urokinase-Type Plasminogen Activator | 2018 |
Epigallocatechin-3-gallate protects against the exacerbation of allergic eosinophilic inflammation associated with obesity in mice.
Topics: Animals; Antioxidants; Asthma; Catechin; Disease Models, Animal; Eosinophils; Inflammation; Lung; Male; Mice, Inbred C57BL; Obesity; Oxidative Stress | 2018 |
Interaction Between Phenolic Compounds and Lipase: The Influence of Solubility and Presence of Particles in the IC
Topics: Caffeic Acids; Catechin; Chlorogenic Acid; Enzyme Inhibitors; Flavonoids; Humans; Lipase; Phenols; Quercetin; Reproducibility of Results; Solubility | 2018 |
Metabolic Flux Enhancement and Transcriptomic Analysis Displayed the Changes of Catechins Following Long-Term Pruning in Tea Trees ( Camellia sinensis).
Topics: Camellia sinensis; Catechin; Crop Production; Gene Expression Profiling; Humans; Plant Proteins; Taste; Tea; Trees | 2018 |
Search of Neuroprotective Polyphenols Using the "Overlay" Isolation Method.
Topics: Amyloid beta-Peptides; Animals; Catechin; Cell Culture Techniques; Cell Differentiation; Culture Media, Serum-Free; Curcumin; Hormesis; Nerve Growth Factor; Neurons; Neuroprotective Agents; PC12 Cells; Plant Extracts; Plant Leaves; Polyphenols; Rats; Resveratrol; Sasa; Stilbenes; Taxoids | 2018 |
Multiple antiviral approaches of (-)-epigallocatechin-3-gallate (EGCG) against porcine reproductive and respiratory syndrome virus infection in vitro.
Topics: Animals; Antiviral Agents; Catechin; Cell Line; Chlorocebus aethiops; Cytokines; Down-Regulation; Interleukin-6; Interleukin-8; Macrophages, Alveolar; Porcine Reproductive and Respiratory Syndrome; Porcine respiratory and reproductive syndrome virus; Receptors, Virus; Swine; Time Factors; Tumor Necrosis Factor-alpha; Viral Proteins; Virion; Virus Attachment; Virus Replication | 2018 |
Chitosan-based nanoformulated (-)-epigallocatechin-3-gallate (EGCG) modulates human keratinocyte-induced responses and alleviates imiquimod-induced murine psoriasiform dermatitis.
Topics: Administration, Topical; Aminoquinolines; Animals; Antineoplastic Agents; Antioxidants; Catechin; Cell Differentiation; Cells, Cultured; Chitosan; Dermatitis; Filaggrin Proteins; Humans; Imiquimod; Keratinocytes; Mice; Mice, Inbred BALB C; Nanoparticles; Psoriasis | 2018 |
Elastin Stabilization Through Polyphenol and Ferric Chloride Combined Treatment for the Enhancement of Bioprosthetic Heart Valve Anticalcification.
Topics: Animals; Bioprosthesis; Calcinosis; Catechin; Chlorides; Collagen; Cross-Linking Reagents; Elastin; Ferric Compounds; Glutaral; Heart Valve Prosthesis; Male; Pericardium; Polyphenols; Protein Stability; Rats, Sprague-Dawley; Swine; Tannins; Tensile Strength | 2018 |
Study of EGCG induced apoptosis in lung cancer cells by inhibiting PI3K/Akt signaling pathway.
Topics: A549 Cells; Apoptosis; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction | 2018 |
Epigallocatechin-3-gallate inhibited cancer stem cell-like properties by targeting hsa-mir-485-5p/RXRα in lung cancer.
Topics: A549 Cells; Analysis of Variance; Animals; Anticarcinogenic Agents; Carcinoma, Non-Small-Cell Lung; Catechin; Down-Regulation; Gene Knockdown Techniques; Gene Silencing; HEK293 Cells; Humans; Lung Neoplasms; Mice; Mice, Nude; MicroRNAs; Molecular Mimicry; Neoplastic Stem Cells; Retinoid X Receptor alpha; Signal Transduction; Transfection; Up-Regulation; Xenograft Model Antitumor Assays | 2018 |
Influences of epigallocatechin gallate and citric acid on Escherichia coli O157:H7 toxin gene expression and virulence-associated stress response.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Catechin; Cell Membrane Permeability; Citric Acid; Escherichia coli O157; Gene Expression Regulation, Bacterial; Microbial Sensitivity Tests; Porins; Rec A Recombinases; Shiga Toxin 1; Shiga Toxin 2; Sigma Factor; SOS Response, Genetics; Virulence; Virulence Factors | 2018 |
Wound healing can be improved by (-)-epigallocatechin gallate through targeting Notch in streptozotocin-induced diabetic mice.
Topics: Animals; Catechin; Diabetes Mellitus, Experimental; Female; Inflammation; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred ICR; RAW 264.7 Cells; Receptors, Notch; Signal Transduction; Skin; Streptozocin; Wound Healing | 2019 |
Nano-chemotherapeutic efficacy of (-) -epigallocatechin 3-gallate mediating apoptosis in A549 cells: Involvement of reactive oxygen species mediated Nrf2/Keap1signaling.
Topics: A549 Cells; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Particle Size; Reactive Oxygen Species; Signal Transduction; Surface Properties | 2018 |
The Influence of In Vivo Metabolic Modifications on ADMET Properties of Green Tea Catechins-In Silico Analysis.
Topics: Biological Availability; Catechin; Computer Simulation; Humans; Models, Biological; Models, Molecular; Molecular Docking Simulation; Serum Albumin, Human; Software; Tea | 2018 |
Epigallocatechin gallate in combination with eugenol or amarogentin shows synergistic chemotherapeutic potential in cervical cancer cell line.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Catechin; Cell Proliferation; DNA (Cytosine-5-)-Methyltransferase 1; Drug Synergism; Eugenol; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Iridoids; LIM Domain Proteins; Tea; Tumor Suppressor Proteins; Uterine Cervical Neoplasms | 2018 |
Studies on the non-invasive anticancer remedy of the triple combination of epigallocatechin gallate, pulsed electric field, and ultrasound.
Topics: Apoptosis; Autophagy; Caspases; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Combined Modality Therapy; Humans; Neoplasms; Pulsed Radiofrequency Treatment; Reactive Oxygen Species; Ultrasonic Therapy; Ultrasonic Waves | 2018 |
Epigallocatechin-3-gallate location and interaction with late endosomal and plasma membrane model membranes by molecular dynamics.
Topics: Catechin; Cell Membrane; Endosomes; Hydrogen Bonding; Molecular Dynamics Simulation; Polyphenols; Tea | 2019 |
Epigallocatechin-3-gallate protects against 1,3-dichloro-2-propanol-induced lipid accumulation in C57BL/6J mice.
Topics: alpha-Chlorohydrin; Animals; Antioxidants; Catechin; Dyslipidemias; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Mutagens; Protective Agents | 2018 |
Effect of (-)-epicatechin-3-gallate and (-)-epigallocatechin-3-gallate on the binding of tegafur to human serum albumin as determined by spectroscopy, isothermal titration calorimetry, and molecular docking.
Topics: Antioxidants; Binding Sites; Biophysical Phenomena; Calorimetry; Catechin; Humans; Molecular Docking Simulation; Protein Binding; Protein Conformation; Serum Albumin, Human; Spectrometry, Fluorescence; Tegafur; Thermodynamics | 2019 |
Epigallocatechin-3-gallate affects the proliferation, apoptosis, migration and invasion of tongue squamous cell carcinoma through the hippo-TAZ signaling pathway.
Topics: Apoptosis; Carcinoma, Squamous Cell; Catechin; Cell Line; Cell Movement; Cell Proliferation; Humans; Signal Transduction; Tongue Neoplasms; Wound Healing | 2018 |
Epigallocatechin-3-gallate and 6-OH-11-O-Hydroxyphenanthrene Limit BE(2)-C Neuroblastoma Cell Growth and Neurosphere Formation In Vitro.
Topics: Apoptosis; Catechin; Cell Line, Tumor; Cell Survival; Drug Synergism; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplastic Stem Cells; Neuroblastoma; Phenanthrenes; Tea | 2018 |
Epigallocatechin Gallate Attenuates Bladder Dysfunction via Suppression of Oxidative Stress in a Rat Model of Partial Bladder Outlet Obstruction.
Topics: Animals; Anticarcinogenic Agents; Catechin; Disease Models, Animal; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Urinary Bladder; Urinary Bladder Neck Obstruction | 2018 |
Enhanced oral bioavailability of EGCG using pH-sensitive polymeric nanoparticles: characterization and in vivo investigation on nephrotic syndrome rats.
Topics: Administration, Oral; Animals; Biological Availability; Calorimetry, Differential Scanning; Catechin; Crystallography, X-Ray; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Liberation; Hydrogen-Ion Concentration; Kidney; Microscopy, Electron, Transmission; Nanoparticles; Nephrotic Syndrome; Polymers; Powder Diffraction; Proteinuria; Rats, Sprague-Dawley; Renal Agents; Solubility | 2018 |
Probing Gallate-Mediated Selectivity and High-Affinity Binding of Epigallocatechin Gallate: a Way-Forward in the Design of Selective Inhibitors for Anti-apoptotic Bcl-2 Proteins.
Topics: Amino Acid Sequence; Apoptosis; bcl-X Protein; Catechin; Drug Design; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Protein Domains; Proto-Oncogene Proteins c-bcl-2; Substrate Specificity; Thermodynamics | 2019 |
Comparative analysis of fecal phenolic content between normal and obese rats after oral administration of tea polyphenols.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Camellia sinensis; Catechin; Dietary Supplements; Feces; Fermentation; Food Handling; Gastrointestinal Microbiome; Intestinal Absorption; Intestinal Elimination; Male; Obesity; Oxidation-Reduction; Phenols; Phenylacetates; Plant Extracts; Plant Leaves; Polyphenols; Random Allocation; Rats, Sprague-Dawley | 2018 |
Constitutive Polyphenols in Blades and Veins of Grapevine ( Vitis vinifera L.) Healthy Leaves.
Topics: Catechin; Chromatography, High Pressure Liquid; Coumaric Acids; Flavonoids; Fruit; Genotype; Plant Extracts; Plant Leaves; Polyphenols; Tandem Mass Spectrometry; Vitis | 2018 |
Potential ameliorative effects of epigallocatechin‑3‑gallate against testosterone-induced benign prostatic hyperplasia and fibrosis in rats.
Topics: Animals; Catechin; Collagen; Epithelial-Mesenchymal Transition; Fibrosis; Male; MicroRNAs; Oxidative Stress; Prostate; Prostatic Hyperplasia; Rats; Rats, Wistar; Receptors, Androgen; Receptors, Estrogen; Smad3 Protein; Testosterone; Transforming Growth Factor beta1 | 2018 |
EGCG inhibits CSC-like properties through targeting miR-485/CD44 axis in A549-cisplatin resistant cells.
Topics: A549 Cells; Animals; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Proliferation; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Hyaluronan Receptors; Lung Neoplasms; Mice; Mice, Nude; MicroRNAs; Neoplastic Stem Cells; Xenograft Model Antitumor Assays | 2018 |
(-)-Epigallocatechin-3-gallate (EGCG) inhibits starch digestion and improves glucose homeostasis through direct or indirect activation of PXR/CAR-mediated phase II metabolism in diabetic mice.
Topics: alpha-Amylases; alpha-Glucosidases; Animals; Camellia sinensis; Catechin; Constitutive Androstane Receptor; Diabetes Mellitus, Type 2; Gluconeogenesis; Glucose; Homeostasis; Humans; Intestine, Small; Lipogenesis; Liver; Male; Mice; Mice, Inbred ICR; Plant Extracts; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Starch; Sterol Regulatory Element Binding Protein 1 | 2018 |
Bioinformatics analysis of microarray profiling identifies the mechanism of focal adhesion kinase signalling pathway in proliferation and apoptosis of breast cancer cells modulated by green tea polyphenol epigallocatechin 3-gallate.
Topics: Apoptosis; Breast Neoplasms; Catechin; Cell Adhesion; Cell Proliferation; Computational Biology; Down-Regulation; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Nucleosomes; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Tea | 2018 |
Analytical ultracentrifugation in saliva research: Impact of green tea astringency and its significance on the in-vivo aroma release.
Topics: Adult; Catechin; Female; Humans; Male; Saliva; Salivary Proteins and Peptides; Tea; Ultracentrifugation | 2018 |
Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells.
Topics: Antineoplastic Agents; Azepines; Catechin; Cellular Senescence; Chromobox Protein Homolog 5; Drug Screening Assays, Antitumor; Epigenesis, Genetic; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Quinazolines | 2018 |
Epigallocatechin gallate attenuates mitochondrial DNA-induced inflammatory damage in the development of ventilator-induced lung injury.
Topics: Aged; Animals; Bronchoalveolar Lavage Fluid; Catechin; Cells, Cultured; Cytokines; DNA, Mitochondrial; Epithelial Cells; Female; Humans; Inflammation; Lung; Male; Middle Aged; Rats; Rats, Sprague-Dawley; Ventilator-Induced Lung Injury | 2018 |
Achievable Central Nervous System Concentrations of the Green Tea Catechin EGCG Induce Stress in Glioblastoma Cells in Vitro.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Brain Neoplasms; Catechin; Central Nervous System; Dietary Supplements; DNA Modification Methylases; DNA Repair Enzymes; Dose-Response Relationship, Drug; Glioblastoma; Humans; Lomustine; Promoter Regions, Genetic; Reactive Oxygen Species; Tea; Temozolomide; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2018 |
Functionalized epigallocatechin gallate copolymer inhibit dentin matrices degradation: Mechanical, solubilized telopeptide and proteomic assays.
Topics: Bisphenol A-Glycidyl Methacrylate; Catechin; Chlorhexidine; Chromatography, High Pressure Liquid; Dental Materials; Dentin; Enzyme-Linked Immunosorbent Assay; Humans; In Vitro Techniques; Molar; Polyethylene Glycols; Polymers; Polymethacrylic Acids; Proteomics; Tensile Strength; Tooth Demineralization | 2018 |
Cascaded Aptamers-Governed Multistage Drug-Delivery System Based on Biodegradable Envelope-Type Nanovehicle for Targeted Therapy of HER2-Overexpressing Breast Cancer.
Topics: Aptamers, Peptide; Breast Neoplasms; Catechin; Cell Line, Tumor; Coated Materials, Biocompatible; Drug Delivery Systems; Female; Gene Expression Regulation, Neoplastic; Humans; Nanostructures; Receptor, ErbB-2 | 2018 |
Epigallocatechin‑3‑gallate protects against secondary osteoporosis in a mouse model via the Wnt/β‑catenin signaling pathway.
Topics: Animals; beta Catenin; Calcium; Cartilage; Catechin; Cell Proliferation; Cyclin D1; Disease Models, Animal; Humans; Mice; Osteoporosis; PPAR gamma; Tea; Wnt Signaling Pathway | 2018 |
The Effect of Ultrasound, Oxygen and Sunlight on the Stability of (-)-Epigallocatechin Gallate.
Topics: Antioxidants; Catechin; Chromatography, High Pressure Liquid; Drug Stability; Oxygen; Reproducibility of Results; Sunlight; Tea; Ultrasonic Waves | 2018 |
Inhibition of amyloid fibril formation in the variable domain of λ6 light chain mutant Wil caused by the interaction between its unfolded state and epigallocatechin-3-O-gallate.
Topics: Amino Acid Sequence; Amyloid; Ascorbic Acid; Catechin; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Immunoglobulin Light Chains; Methionine; Mutation; Oxidation-Reduction; Peptide Mapping; Protein Binding; Protein Folding; Protein Unfolding; Spectrum Analysis; Thermodynamics | 2018 |
A New Therapeutic Approach for Brain Delivery of Epigallocatechin Gallate: Development and Characterization Studies.
Topics: Animals; Behavior, Animal; Biological Availability; Blood-Brain Barrier; Catechin; Cerebral Infarction; Disease Models, Animal; Drug Compounding; Drug Liberation; Emulsions; Humans; Lipids; Male; Memory Disorders; Mice; Nanoparticles; Neuroprotective Agents; Treatment Outcome | 2019 |
(-)-Epigallocatechin gallate but not chlorogenic acid suppresses EGF-stimulated migration of osteoblasts via attenuation of p38 MAPK activity.
Topics: Animals; Catechin; Cell Line; Cell Movement; Chlorogenic Acid; Epidermal Growth Factor; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Osteoblasts; p38 Mitogen-Activated Protein Kinases | 2018 |
Effects of Epigallocatechin Gallate on Behavioral and Cognitive Impairments, Hypothalamic-Pituitary-Adrenal Axis Dysfunction, and Alternations in Hippocampal BDNF Expression Under Single Prolonged Stress.
Topics: Animals; Brain-Derived Neurotrophic Factor; Catechin; Cognitive Dysfunction; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Hippocampus; Humans; Male; Maze Learning; Memory; Pituitary-Adrenal System; Rats; Stress Disorders, Post-Traumatic; Stress, Physiological | 2018 |
Epigallocatechin-3 gallate prevents pressure overload-induced heart failure by up-regulating SERCA2a via histone acetylation modification in mice.
Topics: Acetylation; Animals; Aortic Diseases; Cardiovascular Agents; Catechin; Constriction, Pathologic; Disease Models, Animal; Heart Failure; Histone Deacetylase 1; Histones; Male; Mice, Inbred C57BL; Promoter Regions, Genetic; Protective Agents; Random Allocation; RNA, Messenger; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Up-Regulation | 2018 |
The Mechanisms of Alpha-Amylase Inhibition by Flavan-3-Ols and the Possible Impacts of Drinking Green Tea on Starch Digestion.
Topics: alpha-Amylases; Amylose; Animals; Catechin; Digestion; Flavonoids; Hydrolysis; Inhibitory Concentration 50; Models, Molecular; Oligosaccharides; Starch; Swine; Tea | 2018 |
A Poloxamer-407 modified liposome encapsulating epigallocatechin-3-gallate in the presence of magnesium: Characterization and protective effect against oxidative damage.
Topics: Antioxidants; Catechin; Cell Line; Drug Liberation; Humans; Hydrogen Peroxide; Liposomes; Magnesium; Nanoparticles; Oxidative Stress; Poloxamer | 2018 |
[Effects of EGCG on Proliferation, Cell Cycle and DAPK1 Gene Methylation of Acute Promyelocytic Leukemia NB4 Cell Line].
Topics: Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Death-Associated Protein Kinases; Humans; Leukemia, Promyelocytic, Acute; Methylation | 2018 |
On the role of epigallocatechin-3-gallate in protecting phospholipid molecules against UV irradiation.
Topics: Antioxidants; Catechin; Lipid Bilayers; Liposomes; Oxidation-Reduction; Phosphatidylglycerols; Principal Component Analysis; Radiation-Protective Agents; Ultraviolet Rays | 2019 |
Lipophilization of EGCG and effects on antioxidant activities.
Topics: Antioxidants; Catechin; Chromatography, High Pressure Liquid; Esterification; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oils; Oxidation-Reduction; Palmitates; Solubility | 2019 |
Suppressing glucose metabolism with epigallocatechin-3-gallate (EGCG) reduces breast cancer cell growth in preclinical models.
Topics: Animals; Apoptosis; Autophagy; Autophagy-Related Protein 5; Beclin-1; Breast Neoplasms; Caspase 3; Caspase 8; Caspase 9; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Glucose; Glucose Transporter Type 1; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Inbred BALB C; Microtubule-Associated Proteins; Polyphenols; Tea; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2018 |
Impact of green tea consumption on the risk of Tuberculosis development - Letter to the Editor.
Topics: Aged; Antioxidants; Catechin; Dietary Exposure; Drinking Behavior; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Mycobacterium tuberculosis; Pakistan; Protective Factors; Tea; Tuberculosis | 2018 |
Effects of green tea, matcha tea and their components epigallocatechin gallate and quercetin on MCF‑7 and MDA-MB-231 breast carcinoma cells.
Topics: Anticarcinogenic Agents; Antioxidants; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Humans; MCF-7 Cells; Quercetin; Receptors, Estrogen; Tamoxifen; Tea | 2019 |
(‑)Epigallocatechin‑3‑gallate attenuates anesthesia‑induced memory deficit in young mice via modulation of nitric oxide expression.
Topics: Anesthesia; Animals; Antioxidants; Apoptosis; Arginine; Biomarkers; Catechin; Disease Models, Animal; Indazoles; Male; Memory; Memory Disorders; Mice; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Oxidative Stress | 2018 |
The tropoelastin and lysyl oxidase treatments increased the content of insoluble elastin in bioprosthetic heart valves.
Topics: Animals; Biomechanical Phenomena; Bioprosthesis; Calcinosis; Catechin; Cross-Linking Reagents; Elastin; Glutaral; Heart Valve Prosthesis; Male; Pericardium; Protein Stability; Protein-Lysine 6-Oxidase; Rats, Sprague-Dawley; Swine; Tropoelastin | 2018 |
Epigallocatechin Gallate-Modified Gelatins with Different Compositions Alter the Quality of Regenerated Bones.
Topics: Animals; Bone Density; Bone Regeneration; Bone Substitutes; Catechin; Gelatin; Guided Tissue Regeneration; Male; Rats; Rats, Sprague-Dawley | 2018 |
Mechanism for antibacterial action of epigallocatechin gallate and theaflavin-3,3'-digallate on Clostridium perfringens.
Topics: Anti-Bacterial Agents; Biflavonoids; Catechin; Clostridium perfringens | 2019 |
Comparison of migration disturbance potency of epigallocatechin gallate (EGCG) synthetic analogs and EGCG PEGylated PLGA nanoparticles in rat neurospheres.
Topics: Animals; Catechin; Cell Movement; Cell Proliferation; Cells, Cultured; Female; Nanoparticles; Neurons; Polyethylene Glycols; Pregnancy; Rats | 2019 |
Candesartan and epigallocatechin-3-gallate ameliorate gentamicin-induced renal damage in rats through p38-MAPK and NF-κB pathways.
Topics: Animals; Benzimidazoles; Biphenyl Compounds; Caspase 3; Catechin; Drug Therapy, Combination; Gene Expression Regulation; Gentamicins; Inflammation; Interleukin-1beta; Kidney Diseases; Male; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Protective Agents; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetrazoles; Tumor Necrosis Factor-alpha | 2019 |
Green tea extract modulates oxidative tissue injury in beta-thalassemic mice by chelation of redox iron and inhibition of lipid peroxidation.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; beta-Thalassemia; Catechin; Hematopoiesis; Hepcidins; Insulin; Iron; Iron Chelating Agents; Lipid Peroxidation; Liver; Malondialdehyde; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction; Oxidative Stress; Pancreas; Tea; Thiobarbituric Acid Reactive Substances | 2018 |
Effect of pH-shifting treatment on structural and functional properties of whey protein isolate and its interaction with (-)-epigallocatechin-3-gallate.
Topics: Catechin; Circular Dichroism; Emulsions; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Protein Structure, Secondary; Solubility; Spectrometry, Fluorescence; Tryptophan; Whey Proteins | 2019 |
Physicochemical and oxidative stability of a soybean oleosome-based emulsion and its in vitro digestive fate as affected by (-)-epigallocatechin-3-gallate.
Topics: Catechin; Emulsions; Glycine max; Humans; Hydrogen-Ion Concentration; Lipid Droplets; Oxidation-Reduction; Plant Extracts | 2018 |
Epigallocatechin-3-O-gallate, the main green tea component, is toxic to Saccharomyces cerevisiae cells lacking the Fet3/Ftr1.
Topics: Catechin; Ceruloplasmin; Copper; Membrane Transport Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Tea | 2018 |
UPLC-Orbitrap-MS/MS combined with chemometrics establishes variations in chemical components in green tea from Yunnan and Hunan origins.
Topics: Apigenin; Catechin; China; Chromatography, High Pressure Liquid; Cluster Analysis; Discriminant Analysis; Plant Extracts; Principal Component Analysis; Tandem Mass Spectrometry; Tea | 2018 |
Protective effect of epigallocatechin gallate on human erythrocytes.
Topics: Antioxidants; Catechin; Dimyristoylphosphatidylcholine; Erythrocyte Membrane; Hemolysis; Humans; Hydrophobic and Hydrophilic Interactions; Hypochlorous Acid; Kinetics; Lipid Bilayers; Oxidants; Phosphatidylethanolamines; Spectrometry, Fluorescence; Thermodynamics | 2019 |
Theaflavin and epigallocatechin-3-gallate synergistically induce apoptosis through inhibition of PI3K/Akt signaling upon depolymerizing microtubules in HeLa cells.
Topics: Animals; Antioxidants; Apoptosis; Biflavonoids; Binding Sites; Catechin; Cell Proliferation; Drug Synergism; G2 Phase Cell Cycle Checkpoints; Goats; HeLa Cells; Humans; M Phase Cell Cycle Checkpoints; Membrane Potential, Mitochondrial; Microtubules; Phosphatidylinositol 3-Kinases; Polymerization; Proto-Oncogene Proteins c-akt; Signal Transduction; Tubulin | 2019 |
Suppression, disaggregation, and modulation of γ-Synuclein fibrillation pathway by green tea polyphenol EGCG.
Topics: Catechin; Cell Nucleus; gamma-Synuclein; Humans; MCF-7 Cells; Neoplasm Proteins; Protein Aggregates; Protein Structure, Secondary; Tea | 2019 |
Antagonistic effect of epigallocatechin-3-gallate on neurotoxicity induced by formaldehyde.
Topics: Animals; Behavior, Animal; Brain; Catechin; Cognitive Dysfunction; Formaldehyde; Heme Oxygenase-1; Male; Maze Learning; Membrane Proteins; Mice; NAD(P)H Dehydrogenase (Quinone); Neuroprotective Agents; Neurotoxicity Syndromes; NF-E2-Related Factor 2 | 2019 |
Epigallocatechin-3-gallate Enhances Radiation Sensitivity in Colorectal Cancer Cells Through Nrf2 Activation and Autophagy.
Topics: Caspase 9; Catechin; Cell Nucleus; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Microtubule-Associated Proteins; NF-E2-Related Factor 2; Protein Transport; Radiation-Sensitizing Agents; Transcriptional Activation | 2018 |
Targeting the DNA Repair Endonuclease ERCC1-XPF with Green Tea Polyphenol Epigallocatechin-3-Gallate (EGCG) and Its Prodrug to Enhance Cisplatin Efficacy in Human Cancer Cells.
Topics: Animals; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Cisplatin; Comet Assay; DNA Repair; DNA-Binding Proteins; Drug Resistance, Neoplasm; Endonucleases; Female; Humans; Mice; Mice, Nude; Platinum; Polyphenols; Prodrugs; Tea | 2018 |
Effects of (-)-Epigallocatechin Gallate (EGCG) on Energy Expenditure and Microglia-Mediated Hypothalamic Inflammation in Mice Fed a High-Fat Diet.
Topics: Adipose Tissue, Brown; Animals; Biomarkers; Blood Glucose; Catechin; Cholesterol; Diet, High-Fat; Disease Models, Animal; Energy Metabolism; Hypothalamus; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Microglia; NF-kappa B; Obesity; Polyphenols; STAT3 Transcription Factor; Tea; Triglycerides | 2018 |
Metabolomics of Green-Tea Catechins on Vascular-Endothelial-Growth-Factor-Stimulated Human-Endothelial-Cell Survival.
Topics: Apoptosis; Camellia sinensis; Catechin; Cell Cycle Checkpoints; Cell Survival; Human Umbilical Vein Endothelial Cells; Humans; Membrane Lipids; Metabolomics; Plant Extracts; Vascular Endothelial Growth Factor A | 2018 |
Conjugation with Phenylalanine Enhances Autophagy-Inducing Activity of (-)-Epigallocatechin Gallate in Hepatic Cells.
Topics: Autophagy; Catechin; Cell Line, Tumor; Hepatocytes; Humans; Lipid Metabolism; Liver; Molecular Structure; Phenylalanine | 2018 |
Biosynthesis of flower-shaped Au nanoclusters with EGCG and their application for drug delivery.
Topics: Animals; Antineoplastic Agents; Catechin; Cell Survival; Delayed-Action Preparations; Doxorubicin; Drug Carriers; Drug Liberation; Gold; HeLa Cells; Hep G2 Cells; Humans; Metal Nanoparticles; Methotrexate; Mice, Inbred BALB C; Particle Size; Surface Properties | 2018 |
Epigallocatechin Gallate Is the Most Effective Catechin Against Antioxidant Stress via Hydrogen Peroxide and Radical Scavenging Activity.
Topics: Animals; Antioxidants; Catechin; Cell Line; Cell Survival; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; Hydroxyl Radical; Mice; Neurons; Oxidative Stress | 2018 |
Evaluation of the neuroprotective effect of EGCG: a potential mechanism of mitochondrial dysfunction and mitochondrial dynamics after subarachnoid hemorrhage.
Topics: Animals; Apoptosis; Autophagy; Catechin; Cytochromes c; Humans; Male; Mice; Mitochondria; Mitochondrial Dynamics; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species; Subarachnoid Hemorrhage | 2018 |
Secretion of Tau via an Unconventional Non-vesicular Mechanism.
Topics: Adenosine Triphosphate; Animals; Calcium; Catechin; Cell Line; Cell Membrane; Heparin; Lipids; Mice; Neurons; Proteoglycans; Rats; tau Proteins | 2018 |
Membrane order and ionic strength modulation of the inhibition of the membrane-bound acetylcholinesterase by epigallocatechin‑3‑gallate.
Topics: Acetylcholinesterase; Catechin; Cholesterol; Cholinesterase Inhibitors; Erythrocyte Membrane; Humans; Ions; Kinetics; Lipid Bilayers; Osmolar Concentration; Salts; Solubility; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared | 2019 |
Modulation of multidrug resistant in cancer cells by EGCG, tannic acid and curcumin.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Catechin; Curcumin; Digitonin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Fluoresceins; Humans; Polyphenols; Rhodamine 123; Tannins | 2018 |
Epigallocatechin gallate attenuates uric acid-induced injury in rat renal interstitial fibroblasts NRK-49F by up-regulation of miR-9.
Topics: Animals; Apoptosis; Catechin; Cells, Cultured; Cytokines; Fibroblasts; Kidney; MicroRNAs; Rats; Uric Acid | 2018 |
Zinc boosts EGCG's hIAPP amyloid Inhibition both in solution and membrane.
Topics: Amyloid; Animals; Catechin; Cell Line, Tumor; Cell Membrane; Cell Survival; Drug Synergism; Humans; Islet Amyloid Polypeptide; Protein Aggregation, Pathological; Rats; Solutions; Zinc | 2019 |
Efficient Synthesis of Theaflavin 3-Gallate by a Tyrosinase-Catalyzed Reaction with (-)-Epicatechin and (-)-Epigallocatechin Gallate in a 1-Octanol/Buffer Biphasic System.
Topics: 1-Octanol; Agaricus; Biflavonoids; Biocatalysis; Catechin; Dimerization; Fungal Proteins; Gallic Acid; Molecular Structure; Monophenol Monooxygenase; Oxidation-Reduction | 2018 |
Microsomal pre-receptor cortisol production is inhibited by resveratrol and epigallocatechin gallate through different mechanisms.
Topics: Animals; Catechin; Chromatography, High Pressure Liquid; Cortisone; Hydrocortisone; Male; Microsomes, Liver; Rats; Resveratrol | 2019 |
Osteogenesis of Multipotent Progenitor Cells using the Epigallocatechin Gallate-Modified Gelatin Sponge Scaffold in the Rat Congenital Cleft-Jaw Model.
Topics: Adipose Tissue; Animals; Catechin; Cell Dedifferentiation; Cells, Cultured; Cleft Palate; Gelatin; Male; Microscopy, Electron, Scanning; Multipotent Stem Cells; Osteogenesis; Rats; Regenerative Medicine | 2018 |
Spatial changes in leaf biochemical profile of two tea cultivars following cold storage under two different vapour pressure deficit (VPD) conditions.
Topics: Caffeine; Camellia sinensis; Catechin; Cold Temperature; Food Storage; Plant Leaves; Theobromine; Vapor Pressure | 2019 |
Comprehensive NMR analysis of two kinds of post-fermented tea and their anti-glycation activities in vitro.
Topics: Bacteria; Bioreactors; Catechin; Glycosylation; Humans; Magnetic Resonance Spectroscopy; Plant Extracts; Plant Leaves; Principal Component Analysis; Serum Albumin; Tea | 2019 |
Diallyl disulfide potentiates anti-obesity effect of green tea in high-fat/high-sucrose diet-induced obesity.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Allyl Compounds; Animals; Anti-Obesity Agents; Body Weight; Catechin; Cyclic Nucleotide Phosphodiesterases, Type 5; Diet, High-Fat; Disulfides; Gene Expression Regulation; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Peroxisome Proliferator-Activated Receptors; Sucrose; Tea | 2019 |
G3BP1 promotes DNA binding and activation of cGAS.
Topics: Animals; Autoantigens; Autoimmune Diseases of the Nervous System; Catechin; Clustered Regularly Interspaced Short Palindromic Repeats; Cytosol; Disease Models, Animal; DNA; DNA Helicases; Exodeoxyribonucleases; HEK293 Cells; HeLa Cells; Humans; Interferons; Mice; Mice, Knockout; Multiprotein Complexes; Nervous System Malformations; Neuroprotective Agents; Nucleotidyltransferases; Phosphoproteins; Poly-ADP-Ribose Binding Proteins; Protein Binding; RNA Helicases; RNA Recognition Motif Proteins | 2019 |
Gelatin-epigallocatechin gallate nanoparticles with hyaluronic acid decoration as eye drops can treat rabbit dry-eye syndrome effectively via inflammatory relief.
Topics: Animals; Catechin; Cell Survival; Cytokines; Disease Models, Animal; Dry Eye Syndromes; Epithelial Cells; Epithelium, Corneal; Gelatin; Humans; Hyaluronic Acid; Inflammation; Male; Nanoparticles; Ophthalmic Solutions; Particle Size; Rabbits; Rats; Sus scrofa; Tears; Treatment Outcome | 2018 |
The Effect of Different Treatments of (-)-Epigallocatechin-3-Gallate on Colorectal Carcinoma Cell Lines.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caco-2 Cells; Catechin; Cell Cycle; Cell Line, Tumor; Colorectal Neoplasms; Drug Stability; HCT116 Cells; Humans; Proteins | 2018 |
EGCG protects cardiomyocytes against hypoxia-reperfusion injury through inhibition of OMA1 activation.
Topics: Animals; Catechin; Fibroblasts; Metalloproteases; Mice; Mitochondrial Proteins; Myocardial Reperfusion Injury; Myocytes, Cardiac | 2019 |
[Effect of EGCG on oxidative stress and Nrf2/HO-1 pathway in neurons exposed to oxygen-glucose deprivation/reperfusion].
Topics: Animals; Catechin; Cell Survival; Cells, Cultured; Gene Expression Regulation; Glucose; Heme Oxygenase-1; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Oxygen; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2018 |
Nanomedicine for neuroprotection.
Topics: Animals; Catechin; Epilepsy, Temporal Lobe; Humans; Nanomedicine; Nanoparticles; Neuroprotection; Neuroprotective Agents; Reperfusion Injury; Sphingomyelin Phosphodiesterase | 2019 |
Inhibitory effect of epigallocatechin-3-O-gallate on α-glucosidase and its hypoglycemic effect via targeting PI3K/AKT signaling pathway in L6 skeletal muscle cells.
Topics: Acarbose; alpha-Glucosidases; Animals; Biological Transport; Catechin; Cell Line; Cell Membrane; Glucose; Glucose Transporter Type 4; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Molecular Docking Simulation; Muscle Fibers, Skeletal; Phosphatidylinositol 3-Kinases; Polyphenols; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Tea | 2019 |
Effects of Lactobacillus salivarius WB21 combined with green tea catechins on dental caries, periodontitis, and oral malodor.
Topics: Antibiosis; Catechin; Dental Caries; Fusobacterium nucleatum; Glucans; Halitosis; Ligilactobacillus salivarius; Microbial Sensitivity Tests; Periodontitis; Porphyromonas gingivalis; Prevotella intermedia; Probiotics; Streptococcus mutans; Tea | 2019 |
Novel Clofarabine-Based Combinations with Polyphenols Epigenetically Reactivate Retinoic Acid Receptor Beta, Inhibit Cell Growth, and Induce Apoptosis of Breast Cancer Cells.
Topics: Apoptosis; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Clofarabine; Cyclin-Dependent Kinase Inhibitor p21; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genistein; Humans; Inhibitory Concentration 50; Polyphenols; Promoter Regions, Genetic; PTEN Phosphohydrolase; Receptors, Retinoic Acid; Transcription, Genetic; Up-Regulation | 2018 |
Co-Encapsulation of EGCG and Quercetin in Liposomes for Optimum Antioxidant Activity.
Topics: Antioxidants; Catechin; Food Handling; Lecithins; Liposomes; Microscopy, Electron, Transmission; Particle Size; Quercetin | 2019 |
Development of transgenic Caenorhabditis elegans expressing human transthyretin as a model for drug screening.
Topics: Amyloid Neuropathies, Familial; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Catechin; Disease Models, Animal; Drug Evaluation, Preclinical; Green Fluorescent Proteins; Humans; Locomotion; Longevity; Neuroprotective Agents; Prealbumin; Recombinant Fusion Proteins; Staining and Labeling | 2018 |
"Cell-addictive" dual-target traceable nanodrug for Parkinson's disease treatment via flotillins pathway.
Topics: alpha-Synuclein; Animals; Animals, Genetically Modified; Catechin; Cell Line; Disease Models, Animal; Dopaminergic Neurons; Drug Carriers; Humans; Membrane Proteins; Mice; Molecular Targeted Therapy; Nanoparticles; Neuroprotective Agents; Parkinson Disease; Protein Aggregation, Pathological; Treatment Outcome | 2018 |
Epigallocatechin-3 Gallate Inhibits
Topics: Adult; Alopecia Areata; Catechin; CD8-Positive T-Lymphocytes; Cost-Benefit Analysis; Female; HLA-B Antigens; HLA-DR Antigens; Humans; Interferon Regulatory Factor-1; Interferon-gamma; Janus Kinase 2; Signal Transduction; STAT1 Transcription Factor | 2018 |
(-)-Epigallocatechin-3-Gallate (EGCG) Enhances Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells.
Topics: Antioxidants; Catechin; Cell Differentiation; Gene Expression Regulation; Humans; Mesenchymal Stem Cells; Osteogenesis | 2018 |
Combined treatment with the phenolics (-)-epigallocatechin-3-gallate and ferulic acid improves cognition and reduces Alzheimer-like pathology in mice.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Behavior, Animal; Catechin; Cognitive Dysfunction; Coumaric Acids; Disease Models, Animal; Drug Therapy, Combination; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Presenilin-1 | 2019 |
Effects and mechanism of epigallocatechin-3-gallate on apoptosis and mTOR/AKT/GSK-3β pathway in substantia nigra neurons in Parkinson rats.
Topics: alpha-Synuclein; Animals; Apoptosis; Catechin; Glycogen Synthase Kinase 3 beta; Male; Neuroprotective Agents; Parkinsonian Disorders; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Substantia Nigra; TOR Serine-Threonine Kinases; Treatment Outcome | 2019 |
Microbiota facilitates the formation of the aminated metabolite of green tea polyphenol (-)-epigallocatechin-3-gallate which trap deleterious reactive endogenous metabolites.
Topics: Aldehydes; Amination; Ammonia; Animals; Catechin; Free Radical Scavengers; Gastrointestinal Microbiome; Germ-Free Life; HCT116 Cells; HT29 Cells; Humans; Malondialdehyde; Mice; Oxidation-Reduction; Pyruvaldehyde; Quinones; Sorption Detoxification; Tea | 2019 |
Epigallocatechin-3-gallate added after thawing to frozen dog semen: Effect on sperm parameters and ability to bind to oocytes' zona pellucida.
Topics: Animals; Catechin; Cryopreservation; Cryoprotective Agents; Dogs; Male; Oocytes; Semen Preservation; Sperm-Ovum Interactions; Spermatozoa; Zona Pellucida | 2019 |
Stabilization of apo α-lactalbumin by binding of epigallocatechin-3-gallate: Experimental and molecular dynamics study.
Topics: Animals; Apoproteins; Binding Sites; Calcium; Catechin; Hydrogen-Ion Concentration; Lactalbumin; Molecular Dynamics Simulation; Protein Binding; Protein Denaturation; Protein Stability; Protein Structure, Secondary; Spectrometry, Fluorescence | 2019 |
Dietary antioxidants as a source of hydrogen peroxide.
Topics: Antioxidants; Catalase; Catechin; Cell Line, Tumor; Cell Survival; Humans; Hydrogen Peroxide; Oxidation-Reduction; Polyphenols; Propyl Gallate; Quercetin; Tea; Transition Elements | 2019 |
Complex Structures of Monoglucosylrutin with ent-Gallocatechin-3- O-gallate and Epigallocatechin-3- O-gallate in Aqueous Solutions and the Mechanism of Color Change Induced by Complexation.
Topics: Catechin; Color; Molecular Dynamics Simulation; Rutin; Solutions | 2019 |
(-)-Epigallocatechin-3-gallate, reduces corneal damage secondary from experimental grade II alkali burns in mice.
Topics: Alkalies; Animals; Antioxidants; Burns, Chemical; Catechin; Caustics; Cell Cycle; Cell Differentiation; Cell Line; Cell Proliferation; Cornea; Corneal Neovascularization; Corneal Opacity; Epithelium, Corneal; Eye Burns; Mice; Rabbits; Sodium Hydroxide; Wound Healing | 2019 |
Diet supplemented with phytochemical epigallocatechin gallate and probiotic Lactobacillus fermentum confers second generation synbiotic effects by modulating cellular immune responses and antioxidant capacity in aging mice.
Topics: Aging; Animals; Antioxidants; Catechin; Diet; Disease Models, Animal; Immunity, Cellular; Immunosenescence; Limosilactobacillus fermentum; Male; Mice; Oxidative Stress; Probiotics; Synbiotics | 2019 |
(-)-Epigallocatechin-3-Gallate Decreases Osteoclastogenesis via Modulation of RANKL and Osteoprotegrin.
Topics: Animals; Catechin; Cell Cycle; Cell Line; Cell Survival; Gene Expression; Mice; Osteoclasts; Osteogenesis; Osteoprotegerin; RANK Ligand; RAW 264.7 Cells; RNA, Messenger; Tartrate-Resistant Acid Phosphatase | 2019 |
Protective Effects of Epigallocatechin-3-Gallate from Green Tea in Various Kidney Diseases.
Topics: Catechin; Humans; Kidney; Kidney Diseases; Protective Agents; Tea | 2019 |
Covalent modification of β-lactoglobulin by (-)-epigallocatechin-3-gallate results in a novel antioxidant molecule.
Topics: Antioxidants; Biphenyl Compounds; Catechin; Copper; Free Radical Scavengers; Humans; Iron Chelating Agents; Lactoglobulins; Lipoproteins, LDL; Malondialdehyde; Oxidation-Reduction; Picrates; Spectrometry, Fluorescence | 2019 |
Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins.
Topics: Analysis of Variance; Bisphenol A-Glycidyl Methacrylate; Camphor; Catechin; Cell Line; Cell Survival; Compressive Strength; Dentin; Dentin-Bonding Agents; Elastic Modulus; Fibroblasts; Flexural Strength; Humans; Materials Testing; Methacrylates; Microscopy, Electron, Scanning; Polymerization; Reference Values; Reproducibility of Results; Solubility; Surface Properties; Tensile Strength; Time Factors; Water | 2019 |
Epigallocatechin‑3‑gallate modulates long non‑coding RNA and mRNA expression profiles in lung cancer cells.
Topics: Catechin; Cell Line, Tumor; Computational Biology; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; RNA, Long Noncoding; RNA, Messenger; Signal Transduction | 2019 |
Tea polyphenols protect gingival keratinocytes against TNF-α-induced tight junction barrier dysfunction and attenuate the inflammatory response of monocytes/macrophages.
Topics: Biflavonoids; Catechin; Cell Line, Tumor; Cytokines; Gingiva; Humans; Inflammation; Keratinocytes; Macrophages; Monocytes; NF-kappa B; Periodontitis; Plant Extracts; Polyphenols; Protective Agents; Tea; Tight Junctions; Tumor Necrosis Factor-alpha; U937 Cells | 2019 |
Involvement of pRb-E2F pathway in green tea extract-induced growth inhibition of human myeloid leukemia cells.
Topics: Apoptosis; Catechin; Cell Cycle; Cell Proliferation; E2F Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid; Phosphorylation; Plant Extracts; Retinoblastoma Protein; Signal Transduction; Tea; Tumor Cells, Cultured | 2019 |
Oxidative Epigallocatechin Gallate Coating on Polymeric Substrates for Bone Tissue Regeneration.
Topics: Adipose Tissue; Animals; Bone Regeneration; Catechin; Cell Differentiation; Coated Materials, Biocompatible; Mice; Mice, Inbred ICR; Nanofibers; Osteoclasts; Polyesters; RAW 264.7 Cells; Skull; Stem Cells | 2019 |
Combination of Epigallocatechin Gallate and Sulforaphane Counteracts In Vitro Oxidative Stress and Delays Stemness Loss of Amniotic Fluid Stem Cells.
Topics: Amniotic Fluid; Catechin; Humans; Isothiocyanates; Oxidative Stress; Reactive Oxygen Species; Stem Cells; Sulfoxides | 2018 |
Coordination microparticle vaccines engineered from tumor cell templates.
Topics: Actin Cytoskeleton; Aluminum; Animals; Cancer Vaccines; Catechin; Cell Line, Tumor; Cell Survival; Clathrin; Coordination Complexes; Dendritic Cells; Endocytosis; Mice; Microscopy, Confocal; Neoplasms; Transplantation, Homologous | 2019 |
Effects of EGCG on proliferation and apoptosis of gastric cancer SGC7901 cells via down-regulation of HIF-1α and VEGF under a hypoxic state.
Topics: Apoptosis; Catechin; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; Drug Screening Assays, Antitumor; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Stomach Neoplasms; Vascular Endothelial Growth Factor A | 2019 |
Encapsulation of EGCG and esterified EGCG derivatives in double emulsions containing Whey Protein Isolate, Bacterial Cellulose and salt.
Topics: Catechin; Cellulose; Drug Compounding; Drug Stability; Emulsions; Esterification; Sodium Chloride; Stearic Acids; Viscosity; Whey Proteins | 2019 |
(-)-Epigallocatechin-3-gallate (EGCG) enhances healing of femoral bone defect.
Topics: Animals; Biomechanical Phenomena; Bone Density Conservation Agents; Bone Morphogenetic Protein 2; Catechin; Femur; Male; Rats, Sprague-Dawley; Wound Healing; X-Ray Microtomography | 2019 |
Effect of epigallocatechin-3- gallate solutions on bond durability at the adhesive interface in caries-affected dentin.
Topics: Adhesiveness; Catechin; Dental Bonding; Dental Caries; Dentin; Humans; Solutions; Time Factors | 2019 |
Next-Generation Sequencing Reveals the Role of Epigallocatechin-3-Gallate in Regulating Putative Novel and Known microRNAs Which Target the MAPK Pathway in Non-Small-Cell Lung Cancer A549 Cells.
Topics: Carcinoma, Non-Small-Cell Lung; Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; High-Throughput Nucleotide Sequencing; Humans; Lung Neoplasms; MAP Kinase Signaling System; MicroRNAs; Nucleic Acid Conformation; Reproducibility of Results; Transcriptome | 2019 |
Habitat management as a safe and effective approach for improving yield and quality of tea (Camellia sinensis) leaves.
Topics: Camellia sinensis; Catechin; Crop Production; Ecosystem; Metabolomics; Plant Leaves | 2019 |
Identification of epithelial-specific ETS-1 (ESE-1) as a tumor suppressor and molecular target of green tea compound, EGCG.
Topics: Animals; Antineoplastic Agents, Phytogenic; Azoxymethane; Caco-2 Cells; Catechin; Cell Line, Tumor; Cell Movement; Cell Nucleus; Colonic Neoplasms; Dextran Sulfate; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; HCT116 Cells; HT29 Cells; Humans; Mice; Nuclear Localization Signals; Proto-Oncogene Proteins c-ets; Transcription Factors; Xenograft Model Antitumor Assays | 2019 |
Biocompatible Heat-Shock Protein Inhibitor-Delivered Flowerlike Short-Wave Infrared Nanoprobe for Mild Temperature-Driven Highly Efficient Tumor Ablation.
Topics: Animals; Catechin; Cell Line, Tumor; Coated Materials, Biocompatible; HSP90 Heat-Shock Proteins; Humans; Hyperthermia, Induced; Infrared Rays; Magnetic Resonance Imaging; Mice; Mice, Nude; Nanostructures; Neoplasm Proteins; Neoplasms, Experimental | 2019 |
Whey Protein Complexes with Green Tea Polyphenols: Antimicrobial, Osteoblast-Stimulatory, and Antioxidant Activities.
Topics: Adult; Anti-Bacterial Agents; Antioxidants; Bacteria; Catechin; Cell Differentiation; Cell Line; Cell Proliferation; Cells, Cultured; Fibroblasts; Humans; Male; Osteoblasts; Osteogenesis; Polyphenols; Tea; Whey Proteins; Young Adult | 2018 |
Effect of blue light irradiation on the stability of phospholipid molecules in the presence of epigallocatechin-3-gallate.
Topics: Catechin; Light; Phospholipids | 2019 |
Anti-proliferative and anti-apoptotic potential effects of epigallocatechin-3-gallate and/or metformin on hepatocellular carcinoma cells: in vitro study.
Topics: Anticarcinogenic Agents; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Catechin; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Glypicans; Hep G2 Cells; Humans; Liver Neoplasms; Metformin; RNA, Long Noncoding; Signal Transduction; Survivin; Vascular Endothelial Growth Factor A | 2019 |
Effects of Microbial Metabolites of (-)-Epigallocatechin Gallate on Glucose Uptake in L6 Skeletal Muscle Cell and Glucose Tolerance in ICR Mice.
Topics: AMP-Activated Protein Kinases; Animals; Blood Glucose; Catechin; Cell Line; Gastrointestinal Microbiome; Glucose; Glucose Tolerance Test; Hypoglycemic Agents; Lactones; Male; Mice; Mice, Inbred ICR; Muscle Fibers, Skeletal; Myoblasts, Skeletal; Phosphorylation; Signal Transduction | 2019 |
RNA-seq analysis of diet-driven obesity and anti-obesity effects of quercetin glucoside or epigallocatechin gallate in Drosophila adults.
Topics: Animals; Anti-Obesity Agents; Body Weight; Catechin; Diet, High-Fat; Disease Models, Animal; Drosophila; Drug Evaluation, Preclinical; Female; Gene Expression Regulation; Glucosides; Humans; Lipid Metabolism; Male; Metabolomics; Obesity; Oxidative Stress; Quercetin; RNA-Seq; RNA, Messenger; Species Specificity | 2019 |
Fabrication and characterization of functional protein-polysaccharide-polyphenol complexes assembled from lactoferrin, hyaluronic acid and (-)-epigallocatechin gallate.
Topics: Catechin; Cosmetics; Functional Food; Hyaluronic Acid; Lactoferrin; Technology, Pharmaceutical | 2019 |
The science of tea's mood-altering magic.
Topics: Adenosine; Affect; Alpha Rhythm; Animals; Antioxidants; Behavior; Beta Rhythm; Blood-Brain Barrier; Caffeine; Catechin; Cognition; Dementia; Depression; Exercise; gamma-Aminobutyric Acid; Glutamates; Humans; Hydrocortisone; Life Style; Mental Health; Middle Aged; Stress, Psychological; Tea; Theta Rhythm | 2019 |
How climate change might affect tea.
Topics: Animals; Catechin; China; Climate Change; Crop Production; Health; Humans; India; Insecta; Nitrogen Fixation; Plant Transpiration; Rain; Seasons; Taste; Tea; Temperature; Time Factors | 2019 |
Tea's value as a cancer therapy is steeped in uncertainty.
Topics: Animals; Biological Products; Case-Control Studies; Catechin; Cell Line, Tumor; China; Cohort Studies; Dietary Supplements; Disease Models, Animal; Female; Humans; Incidence; Japan; Life Style; Male; Metabolic Syndrome; Mice; Neoplasms; Plant Extracts; Prostatic Neoplasms; Sex Factors; Smoking; Sunitinib; Tea; Uncertainty | 2019 |
The protective effect of epigallocatechin 3-gallate on mouse pancreatic islets via the Nrf2 pathway.
Topics: Animals; Blood Glucose; Catechin; Cell Survival; Gene Expression; Heme Oxygenase-1; In Vitro Techniques; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Mice, Inbred C57BL; Mice, Inbred ICR; NF-E2-Related Factor 2; Reactive Oxygen Species; RNA, Messenger; Tissue Culture Techniques; Transplantation Conditioning | 2019 |
A Polyphenol-Enriched Supplement Exerts Potent Epigenetic-Protective Activity in a Cell-Based Model of Brain Ischemia.
Topics: Acetylation; Animals; Brain Ischemia; Catechin; Cell Culture Techniques; Dietary Supplements; Epigenesis, Genetic; Histones; Mice; Mice, Inbred C57BL; Neuroprotective Agents; NF-kappa B; Polyphenols; Quercetin; Resveratrol; Transcription Factor RelA | 2019 |
Methylomic correlates of autophagy activity in cystic fibrosis.
Topics: Animals; Autophagy; Catechin; Cells, Cultured; Cystic Fibrosis; Macrophages; Mice; Mice, Inbred C57BL | 2019 |
Cell assay for the identification of amyloid inhibitors in systemic AA amyloidosis.
Topics: Amyloidosis; Animals; Biological Assay; Catechin; Cell Line, Tumor; Humans; Mice; Models, Biological; Protein Aggregation, Pathological; Serum Amyloid A Protein | 2019 |
(-)-Epigallocatechin Gallate (EGCG) Enhances the Sensitivity of Colorectal Cancer Cells to 5-FU by Inhibiting GRP78/NF-κB/miR-155-5p/MDR1 Pathway.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Catechin; Colorectal Neoplasms; DNA Damage; Drug Interactions; Drug Resistance, Neoplasm; Endoplasmic Reticulum Chaperone BiP; Fluorouracil; Gene Expression; HCT116 Cells; Heat-Shock Proteins; Humans; MicroRNAs; NF-kappa B; Signal Transduction | 2019 |
Coadministration of epigallocatechin-3-gallate (EGCG) and caffeine in low dose ameliorates obesity and nonalcoholic fatty liver disease in obese rats.
Topics: Animals; Body Weight; Caffeine; Catechin; Diet, High-Fat; Dose-Response Relationship, Drug; Drug Therapy, Combination; Male; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Rats; Rats, Sprague-Dawley; Tea | 2019 |
Methionine oxidation in α-synuclein inhibits its propensity for ordered secondary structure.
Topics: alpha-Synuclein; Catechin; Humans; Lewy Bodies; Methionine; Oxidation-Reduction; Parkinson Disease; Protein Aggregates; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary | 2019 |
Impact of Bioconversion of Gallated Catechins and Flavonol Glycosides on Bioaccessibility and Intestinal Cellular Uptake of Catechins.
Topics: Biological Availability; Biotransformation; Caco-2 Cells; Camellia sinensis; Catechin; Flavonols; Glycosides; Humans; Intestinal Mucosa; Plant Extracts; Tea | 2019 |
Green tea catechins alleviate autoimmune symptoms and visual impairment in a murine model for human chronic intraocular inflammation by inhibiting Th17-associated pro-inflammatory gene expression.
Topics: Animals; Catechin; Disease Models, Animal; Electroretinography; Inflammation; Interleukin-17; Interleukin-6; Mice; Microscopy, Confocal; Papilledema; Tea; Th17 Cells; Tomography, Optical Coherence; Tumor Necrosis Factor-alpha; Uveitis; Vision Disorders | 2019 |
Surface tethering of stem cells with H
Topics: Animals; Catechin; Chick Embryo; Chorioallantoic Membrane; Colloids; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Manganese Compounds; Mesenchymal Stem Cells; Oxidation-Reduction; Oxidative Stress; Oxides; Reactive Oxygen Species | 2019 |
Effects of Tea-Polysaccharide Conjugates and Metal Ions on Precipitate Formation by Epigallocatechin Gallate and Caffeine, the Key Components of Green Tea Infusion.
Topics: Caffeine; Catechin; Chemical Precipitation; Ions; Metals; Polysaccharides; Tea | 2019 |
Characterization of Cationic Modified Debranched Starch and Formation of Complex Nanoparticles with κ-Carrageenan and Low Methoxyl Pectin.
Topics: Anti-Bacterial Agents; Carrageenan; Catechin; Cations; Drug Carriers; Nanoparticles; Pectins; Staphylococcus aureus; Starch | 2019 |
A novel role of HuR in -Epigallocatechin-3-gallate (EGCG) induces tumour cells apoptosis.
Topics: ADAM10 Protein; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Apoptosis; bcl-2-Associated X Protein; Catechin; ELAV-Like Protein 1; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; MAP Kinase Signaling System; Membrane Proteins; Neoplasms; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Rats | 2019 |
In silico and in vitro comparative activity of green tea components against Leishmania infantum.
Topics: Amide Synthases; Antioxidants; Arginase; Catechin; Cell Proliferation; Computer Simulation; Iran; Leishmania infantum; Leishmaniasis, Visceral; Microbial Sensitivity Tests; Molecular Docking Simulation; Pentamidine; Plant Exudates; Protease Inhibitors; Tea | 2019 |
(-)-Epigallocatechin-3-gallate-mediated formation of myofibrillar protein emulsion gels under malondialdehyde-induced oxidative stress.
Topics: Animals; Calorimetry, Differential Scanning; Catechin; Emulsions; Gels; Malondialdehyde; Meat Products; Muscle Proteins; Myofibrils; Oxidative Stress; Rheology; Solubility; Swine | 2019 |
Oligomerization mechanism of tea catechins during tea roasting.
Topics: Carbon Isotopes; Catechin; Chromatography, High Pressure Liquid; Isotope Labeling; Magnetic Resonance Spectroscopy; Plant Leaves; Polymerization; Spectrophotometry; Sugars; Tea; Temperature | 2019 |
Synergistic effects of tea polyphenol epigallocatechin 3-O-gallate and azole drugs against oral Candida isolates.
Topics: Antifungal Agents; Azoles; Candida; Candidiasis, Oral; Catechin; Drug Synergism; Ergosterol; Humans; Microbial Sensitivity Tests; Microscopy, Electron; Molecular Docking Simulation; Tea | 2019 |
Epigallocatechin-3-gallate inhibits proliferation and induces apoptosis in odontogenic keratocyst keratinocytes.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Proliferation; Humans; Keratinocytes; MAP Kinase Signaling System; Odontogenic Cysts; Wnt Signaling Pathway | 2019 |
Effects of Epigallocatechin Gallate on the Stability of Epicatechin in a Photolytic Process.
Topics: Catechin; Drug Stability; Molecular Structure; Photolysis; Tea | 2019 |
Epigallocatechin-3-gallate suppresses pain-related and proinflammatory mediators in the subacromial bursa in rotator cuff tendinopathy.
Topics: Aged; Bursa, Synovial; Catechin; Cytokines; Female; Humans; Inflammation Mediators; Male; Middle Aged; Pain; Rotator Cuff; Tendinopathy | 2019 |
Effective Mechanism of (-)-Epigallocatechin Gallate Indicating the Critical Formation Conditions of Amadori Compound during an Aqueous Maillard Reaction.
Topics: Alanine; Arginine; Catechin; Glycation End Products, Advanced; Maillard Reaction; Monosaccharides; Temperature; Xylose | 2019 |
Epigallocatechin-3-gallate protects the testis from damage generated by experimental cryptorchidism in rabbits.
Topics: Animals; Antioxidants; Apoptosis; Catalase; Catechin; Cryptorchidism; Estradiol; Immunohistochemistry; Lipid Peroxidation; Male; Oxidative Stress; Rabbits; Superoxide Dismutase; Testis | 2019 |
Phenolic constituents and antioxidant activity of
Topics: Antioxidants; Capsules; Catechin; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Euphorbia; Flavonoids; Phenols; Plant Extracts | 2020 |
Epigallocatechin-3-Gallate Attenuates Adriamycin-Induced Focal Segmental Glomerulosclerosis via Suppression of Oxidant Stress and Apoptosis by Targeting Hypoxia-Inducible Factor-1α/ Angiopoietin-Like 4 Pathway.
Topics: Angiopoietin-Like Protein 4; Animals; Antioxidants; Apoptosis; Blotting, Western; Catechin; Disease Models, Animal; Doxorubicin; Fluorescent Antibody Technique; Glomerulosclerosis, Focal Segmental; Hypoxia-Inducible Factor 1, alpha Subunit; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Oxidative Stress; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction | 2019 |
(-)-Epigallocatechin-3-Gallate Protects Against Lithium-Pilocarpine-Induced Epilepsy by Inhibiting the Toll-Like Receptor 4 (TLR4)/Nuclear Factor-κB (NF-κB) Signaling Pathway.
Topics: Animals; Catechin; Disease Models, Animal; Epilepsy; Epilepsy, Temporal Lobe; Hippocampus; Lithium; Long-Term Potentiation; Male; Neurons; Neuroprotective Agents; NF-kappa B; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Signal Transduction; Toll-Like Receptor 4 | 2019 |
Prenatal treatment with EGCG enriched green tea extract rescues GAD67 related developmental and cognitive defects in Down syndrome mouse models.
Topics: Animals; Brain; Catechin; Cognition; Disease Models, Animal; Down Syndrome; Dyrk Kinases; Female; Glutamate Decarboxylase; Interneurons; Maternal-Fetal Exchange; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pregnancy; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Tea | 2019 |
Combination of 5-Florouracil and polyphenol EGCG exerts suppressive effects on oral cancer cells exposed to radiation.
Topics: Catechin; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Therapy, Combination; Fluorouracil; Humans; Mouth Neoplasms; Radiation | 2019 |
Green tea-induced epigenetic reactivation of tissue inhibitor of matrix metalloproteinase-3 suppresses prostate cancer progression through histone-modifying enzymes.
Topics: Acetylation; Antineoplastic Agents; Catechin; Cell Line, Tumor; Cell Movement; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Histone Code; Histone Deacetylase 1; Histones; Humans; Male; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Plant Preparations; Polyphenols; Promoter Regions, Genetic; Prostatic Neoplasms; Tea; Tissue Inhibitor of Metalloproteinase-3; Transcriptional Activation | 2019 |
Impact of green tea epigallocatechin-3-gallate on HIF1-α and mTORC2 expression in obese women: anti-cancer and anti-obesity effects?
Topics: Adolescent; Adult; Anti-Obesity Agents; Anticarcinogenic Agents; Catechin; Class Ia Phosphatidylinositol 3-Kinase; Dietary Supplements; Female; Gene Expression Regulation; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mechanistic Target of Rapamycin Complex 2; Middle Aged; Obesity; Phosphatidylinositol 3-Kinases; Young Adult | 2019 |
Epigallocatechin Gallate Inhibits Hepatic Glucose Production in Primary Hepatocytes via Downregulating PKA Signaling Pathways and Transcriptional Factor FoxO1.
Topics: Animals; Catechin; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Forkhead Box Protein O1; Glucose; Hepatocytes; Liver; Mice; Mice, Knockout; Signal Transduction | 2019 |
The Effect of Green and Black Tea Polyphenols on
Topics: Animals; Biflavonoids; BRCA2 Protein; Catechin; Cell Survival; CHO Cells; Cricetinae; Cricetulus; DNA-Binding Proteins; Plant Extracts; Poly(ADP-ribose) Polymerase Inhibitors; Polyphenols; Sister Chromatid Exchange; Synthetic Lethal Mutations; Tea | 2019 |
EGCG-Derivative G28 Shows High Efficacy Inhibiting the Mammosphere-Forming Capacity of Sensitive and Resistant TNBC Models.
Topics: Antineoplastic Agents; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Doxorubicin; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Fatty Acid Synthase, Type I; Female; Gene Expression Regulation, Neoplastic; Humans; Molecular Structure; Neoplastic Stem Cells; Paclitaxel; Triple Negative Breast Neoplasms | 2019 |
Dual-drug loaded nanoparticles of Epigallocatechin-3-gallate (EGCG)/Ascorbic acid enhance therapeutic efficacy of EGCG in a APPswe/PS1dE9 Alzheimer's disease mice model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Ascorbic Acid; Brain; Catechin; Disease Models, Animal; Drug Carriers; Drug Liberation; Endothelial Cells; Male; Mice, Inbred C57BL; Mice, Transgenic; Nanoparticles; Polyethylene Glycols; Polylactic Acid-Polyglycolic Acid Copolymer; Rats | 2019 |
Epigallocatechin-3-gallate inhibits angiotensin II-induced cardiomyocyte hypertrophy via regulating Hippo signaling pathway in H9c2 rat cardiomyocytes.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Cardiomegaly; Catechin; Cell Line; Gene Expression Regulation; Molecular Structure; Myocytes, Cardiac; Natriuretic Peptide, Brain; Protein Serine-Threonine Kinases; Rats; Reactive Oxygen Species; Signal Transduction | 2019 |
Evaluation of epigallocatechin-3-gallate (EGCG) modified collagen in guided bone regeneration (GBR) surgery and modulation of macrophage phenotype.
Topics: Animals; Bone and Bones; Bone Regeneration; Catechin; Cell Adhesion; Cell Differentiation; Cell Survival; Collagen; Guided Tissue Regeneration; Intercellular Signaling Peptides and Proteins; Keratinocytes; Macrophages; Male; Osteoblasts; Osteogenesis; Phenotype; Rats, Sprague-Dawley | 2019 |
The Phosphorylation of IRS1
Topics: Animals; Catechin; Cell Line; Hypoglycemic Agents; Insulin Receptor Substrate Proteins; Insulin Resistance; Muscle Fibers, Skeletal; Palmitates; Phosphorylation; Proto-Oncogene Proteins c-akt; Rosiglitazone; Tea | 2019 |
Visualizing the down-regulation of hTERT mRNA expression using gold-nanoflare probes and verifying the correlation with cancer cell apoptosis.
Topics: Antineoplastic Agents; Apoptosis; Carbocyanines; Catechin; Cell Line, Tumor; Cell Survival; DNA; Down-Regulation; Enzyme Inhibitors; Fluorescence; Fluorescent Dyes; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Gold; Humans; Metal Nanoparticles; Microscopy, Confocal; Microscopy, Fluorescence; Nucleic Acid Hybridization; Oligonucleotides; Oligonucleotides, Antisense; RNA, Messenger; Telomerase; Time Factors | 2019 |
Positive effects of the tea catechin (-)-epigallocatechin-3-gallate on gut bacteria and fitness of Ectropis obliqua Prout (Lepidoptera: Geometridae).
Topics: Animals; Anti-Bacterial Agents; Bacteria; Camellia sinensis; Catechin; Digestive System; Host-Parasite Interactions; Larva; Moths; Plant Leaves; Population Density; Pupa | 2019 |
Development of a liquid chromatography-tandem mass spectrometric (LC-MS/MS) method for simultaneous determination of epigallocatechin-3-gallate, silibinin, and curcumin in plasma and different tissues after oral dosing of Protandim in rats and its applica
Topics: Animals; Catechin; Chromatography, Liquid; Curcumin; Drugs, Chinese Herbal; Male; Plasma; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry; Tissue Distribution | 2019 |
Investigation on the binding interaction between rice glutelin and epigallocatechin-3-gallate using spectroscopic and molecular docking simulation.
Topics: Catechin; Glutens; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Oryza; Plant Proteins; Protein Binding; Protein Structure, Secondary; Spectrometry, Fluorescence; Thermodynamics | 2019 |
The toxicity of coated silver nanoparticles to Daphnia carinata and trophic transfer from alga Raphidocelis subcapitata.
Topics: Animals; Aquatic Organisms; Catechin; Chlorophyceae; Curcumin; Daphnia; Ecosystem; Fresh Water; Humans; Ligands; Metal Nanoparticles; Silver; Silver Nitrate; Surface Properties; Tyrosine; Water Pollutants, Chemical | 2019 |
Evaluation of epigallocatechin-3-gallate (EGCG)-modified scaffold determines macrophage recruitment.
Topics: Animals; Catechin; Cattle; Collagen; Cytokines; Gene Expression Regulation; Inflammation Mediators; Macrophages; Mice; Rats; RAW 264.7 Cells; Receptors, CCR2; Signal Transduction; Tissue Scaffolds | 2019 |
Epigallocatechin gallate (EGCG) and miR-548m reduce HCV entry through repression of CD81 receptor in HCV cell models.
Topics: 3' Untranslated Regions; Case-Control Studies; Catechin; Cell Line; Computer Simulation; Gene Expression Profiling; Gene Expression Regulation; Hepacivirus; Hepatitis C; Humans; MicroRNAs; Tetraspanin 28; Virus Internalization | 2019 |
Bombesin conjugated solid lipid nanoparticles for improved delivery of epigallocatechin gallate for breast cancer treatment.
Topics: Animals; Antineoplastic Agents; Biological Transport; Bombesin; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Survival; Delayed-Action Preparations; Drug Liberation; Female; Humans; Lecithins; Liposomes; Mice, Inbred C57BL; Nanocapsules; Neoplasms, Experimental; Stearic Acids; Surface Properties | 2019 |
In Silico Investigation of the Anti-Tumor Mechanisms of Epigallocatechin-3-Gallate.
Topics: Antineoplastic Agents; Catechin; Computer Simulation; Humans; Neoplasms; Proteins; Signal Transduction; Tea | 2019 |
Maillard-Reacted Whey Protein Isolates and Epigallocatechin Gallate Complex Enhance the Thermal Stability of the Pickering Emulsion Delivery of Curcumin.
Topics: Catechin; Curcumin; Drug Delivery Systems; Drug Stability; Emulsions; Hot Temperature; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Maillard Reaction; Nanoparticles; Particle Size; Whey Proteins | 2019 |
Epigallocatechin-3-gallate inhibits doxorubicin-induced inflammation on human ovarian tissue.
Topics: Adult; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Catechin; Cell Survival; Cytokines; Doxorubicin; Female; Humans; Inflammation; Metalloproteases; Ovary; Protective Agents | 2019 |
Epigallocatechin-3-gallate stimulates autophagy and reduces apoptosis levels in retinal Müller cells under high-glucose conditions.
Topics: Animals; Apoptosis; Autophagy; Catechin; Cell Count; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Glucose; Rats; Retina; Structure-Activity Relationship | 2019 |
Anti-atherogenic effects of CD36-targeted epigallocatechin gallate-loaded nanoparticles.
Topics: Animals; Atherosclerosis; Catechin; CD36 Antigens; Cells, Cultured; Liver; Macrophages, Peritoneal; Male; Mice, Inbred C57BL; Mice, Knockout; Nanoparticles; Receptors, LDL; RNA, Small Interfering | 2019 |
GC-MS-based metabolomic study reveals dynamic changes of chemical compositions during black tea processing.
Topics: Amino Acids; Camellia sinensis; Carotenoids; Catechin; Flavoring Agents; Food Analysis; Gas Chromatography-Mass Spectrometry; Metabolomics; Odorants; Plant Leaves; Taste; Tea; Volatile Organic Compounds | 2019 |
(-)-Epigallocatechin-3-gallate suppresses cigarette smoke-induced inflammation in human cardiomyocytes via ROS-mediated MAPK and NF-κB pathways.
Topics: Antioxidants; Apoptosis; Catechin; Cell Line; Humans; Interleukin-8; MAP Kinase Signaling System; Myocarditis; Myocytes, Cardiac; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Smoking | 2019 |
Regulation of Neprilysin Activity and Cognitive Functions in Rats After Prenatal Hypoxia.
Topics: Animals; Catechin; Cell Line, Tumor; Cerebral Cortex; Cognition; Dendrites; Female; Hippocampus; Humans; Hypoxia; Male; Memory; Neprilysin; Neuroprotective Agents; Pregnancy; Rats, Wistar; Up-Regulation | 2019 |
Evaluation of EGCG Loading Capacity in DMPC Membranes.
Topics: Catechin; Dimyristoylphosphatidylcholine; Lipid Bilayers; Liposomes | 2019 |
Epigallocatechin gallate (EGCG) alters body fat and lean mass through sex-dependent metabolic mechanisms in
Topics: Adipose Tissue; Animals; Antioxidants; Body Composition; Body Weight; Catechin; Down-Regulation; Drosophila melanogaster; Drosophila Proteins; Energy Metabolism; Female; Homeostasis; Insect Hormones; Lipase; Male; Neuropeptides; Oligopeptides; Positive Transcriptional Elongation Factor B; Pyrrolidonecarboxylic Acid; Sex Factors | 2019 |
Intracellular uptake of EGCG-loaded deformable controlled release liposomes for skin cancer.
Topics: Antineoplastic Agents; Catechin; Cell Survival; Cells, Cultured; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Screening Assays, Antitumor; Humans; Liposomes; Molecular Structure; Particle Size; Polysorbates; Skin Absorption; Skin Neoplasms; Structure-Activity Relationship; Surface Properties; Surface-Active Agents | 2020 |
Epigallocatechin-3-gallate inhibits migration of human nasopharyngeal carcinoma cells by repressing MMP-2 expression.
Topics: Catechin; Cell Line, Tumor; Cell Movement; Cell Survival; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Nasopharyngeal Carcinoma; Neoplasm Invasiveness; Proto-Oncogene Proteins c-akt; Pyrimidines; src-Family Kinases | 2019 |
The Effects of Epigallocatechin Gallate (EGCG) on Pulmonary Fibroblasts of Idiopathic Pulmonary Fibrosis (IPF)-A Next-Generation Sequencing and Bioinformatic Approach.
Topics: Biomarkers; Catechin; Computational Biology; Fibroblasts; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; High-Throughput Nucleotide Sequencing; Humans; Idiopathic Pulmonary Fibrosis; MicroRNAs; Transcriptome | 2019 |
Enoxacin and Epigallocatechin Gallate (EGCG) Act Synergistically to Inhibit the Growth of Cervical Cancer Cells in Culture.
Topics: Antineoplastic Combined Chemotherapy Protocols; Catechin; Cell Proliferation; Enoxacin; Female; HeLa Cells; Humans; Uterine Cervical Neoplasms | 2019 |
Epigallocatechin-3-gallate induces telomere shortening and clastogenic damage in glioblastoma cells.
Topics: Catechin; Cell Line, Tumor; Cellular Senescence; DNA Damage; Glioblastoma; Histones; Humans; Phosphorylation; Telomerase; Telomere; Telomere Shortening | 2019 |
Epigallocatechin gallate prevents mitochondrial impairment and cell apoptosis by regulating miR-30a/p53 axis.
Topics: Animals; Apoptosis; Cardiotonic Agents; Catechin; Cell Hypoxia; Cell Survival; Female; Male; Membrane Potential, Mitochondrial; MicroRNAs; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tumor Suppressor Protein p53 | 2019 |
Epigallocatechin gallate ameliorates airway inflammation by regulating Treg/Th17 imbalance in an asthmatic mouse model.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Catechin; Disease Models, Animal; Female; Forkhead Transcription Factors; Immunoglobulin E; Interleukin-10; Interleukin-17; Lung; Mice, Inbred BALB C; Nuclear Receptor Subfamily 1, Group F, Member 3; T-Lymphocytes, Regulatory; Th17 Cells | 2019 |
Modulation of Myb-induced NF-kB -STAT3 signaling and resulting cisplatin resistance in ovarian cancer by dietary factors.
Topics: Antineoplastic Agents; Catechin; Cell Proliferation; Cisplatin; Curcumin; Drug Resistance, Neoplasm; Female; Humans; Isothiocyanates; NF-kappa B; Ovarian Neoplasms; Proto-Oncogene Proteins c-myb; Signal Transduction; STAT3 Transcription Factor; Sulfoxides | 2019 |
Influence of epigallocatechin-3-gallate in promoting proliferation and osteogenic differentiation of human periodontal ligament cells.
Topics: Alkaline Phosphatase; Catechin; Cell Differentiation; Cell Proliferation; Cells, Cultured; Humans; Osteogenesis; Periodontal Ligament | 2019 |
(-)-Epigallocatechin-3-gallate attenuates the toxicity of methylmercury in Caenorhabditis elegans by activating SKN-1.
Topics: Animals; Antioxidants; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Catechin; DNA-Binding Proteins; Dopaminergic Neurons; Larva; Lipid Peroxidation; Locomotion; Methylmercury Compounds; Protective Agents; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Transcription Factors; Up-Regulation | 2019 |
The protective effect of epigallocatechin-3-gallate on testicular oxidative stress in lead-induced toxicity mediated by Cyp19 gene / estradiol level.
Topics: Animals; Aromatase; Catechin; Estradiol; Lead; Male; Oxidative Stress; Protective Agents; Rats; Sperm Count; Sperm Motility; Testis; Testosterone | 2019 |
Visualized analysis of within-tissue spatial distribution of specialized metabolites in tea (Camellia sinensis) using desorption electrospray ionization imaging mass spectrometry.
Topics: Camellia sinensis; Catechin; Gallic Acid; Glutamates; Plant Leaves; Plant Roots; Polyphenols; Spectrometry, Mass, Electrospray Ionization | 2019 |
Molecular Capture Using the Precipitate of Creaming-Down by (-)-Epigallocatechin-3-O-gallate.
Topics: Catechin; Crystallization; Crystallography, X-Ray; Heterocyclic Compounds; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Proton Magnetic Resonance Spectroscopy; Pyrimidines; Stereoisomerism; Water | 2019 |
Influence of protease inhibitors on the degradation of sound, sclerotic and caries-affected demineralized dentin.
Topics: Adolescent; Adult; Catechin; Chlorhexidine; Clostridium histolyticum; Dental Caries; Dentin; Hardness; Humans; Materials Testing; Middle Aged; Molar; Pressure; Protease Inhibitors; Sclerosis; Sound; Tensile Strength; Young Adult | 2019 |
Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus.
Topics: Adaptor Proteins, Signal Transducing; Aged; Alzheimer Disease; Animals; Axin Protein; Catechin; Chromosomes, Human, Pair 21; Disease Models, Animal; Down Syndrome; Down-Regulation; Dyrk Kinases; Female; HEK293 Cells; HeLa Cells; Hippocampus; Humans; Male; Mice; Middle Aged; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; RNA-Seq; Wnt Signaling Pathway | 2019 |
Physicochemical interactions with (-)-epigallocatechin-3-gallate drive structural modification of celiac-associated peptide α
Topics: Camellia sinensis; Catechin; Celiac Disease; Circular Dichroism; Gliadin; Humans; Hydrogen-Ion Concentration; Peptide Fragments; Plant Extracts | 2019 |
Increased BBB permeability contributes to EGCG-caused cognitive function improvement in natural aging rats: pharmacokinetic and distribution analyses.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Catechin; Cerebral Cortex; Cognition; Hippocampus; Male; Maze Learning; Memory; Neuroprotective Agents; Nootropic Agents; Peptide Fragments; Rats, Sprague-Dawley | 2019 |
Caffeine-free hawk tea lowers cholesterol by reducing free cholesterol uptake and the production of very-low-density lipoprotein.
Topics: Animals; Anticholesteremic Agents; Biological Transport, Active; Caffeine; Catechin; Cholesterol; Disease Models, Animal; Dyslipidemias; Feeder Cells; Gastrointestinal Microbiome; Hep G2 Cells; Humans; Kaempferols; Lipid Metabolism; Lipoproteins, VLDL; Litsea; Liver; Male; Models, Biological; Quercetin; Rats; Rats, Sprague-Dawley; Receptors, LDL; Sterol Regulatory Element Binding Protein 2; Teas, Medicinal | 2019 |
Influence of Manothermosonication on the Physicochemical and Functional Properties of Ferritin as a Nanocarrier of Iron or Bioactive Compounds.
Topics: Apoferritins; Apoproteins; Catechin; Drug Carriers; Fabaceae; Hydrogen-Ion Concentration; Iron; Oxidation-Reduction; Plant Proteins; Protein Stability; Solubility; Sonication | 2019 |
Validation and functional analysis of the critical proteins in combination with taurine, epigallocatechin gallate and genistein against liver fibrosis in rats.
Topics: Animals; Catechin; Cell Line; Cell Proliferation; Drug Therapy, Combination; Factor VII; Genistein; Hepatic Stellate Cells; Liver; Liver Cirrhosis, Experimental; Liver Function Tests; Rats, Sprague-Dawley; Taurine | 2019 |
Green Tea Ameliorates Hyperglycemia by Promoting the Translocation of Glucose Transporter 4 in the Skeletal Muscle of Diabetic Rodents.
Topics: Animals; Catechin; Diabetes Mellitus, Experimental; Diet, High-Fat; Fructosamine; Glucose; Glucose Intolerance; Glucose Tolerance Test; Glucose Transporter Type 4; Glycated Hemoglobin; Hyperglycemia; Lipids; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Obesity; Plant Extracts; Rats; Rats, Wistar; Rodentia; Streptozocin; Tea | 2019 |
High Oxidation Stability of Tea Polyphenol-stabilized Highly Crosslinked UHMWPE Under an in Vitro Aggressive Oxidative Condition.
Topics: Antioxidants; Camellia sinensis; Catechin; Free Radicals; Joint Prosthesis; Oxidation-Reduction; Plant Extracts; Polyethylenes; Prosthesis Failure; Squalene; Time Factors; Vitamin E | 2019 |
Formation of N
Topics: Camellia sinensis; Catechin; Food Analysis; Food Handling; Gallic Acid; Glyoxal; Lysine; Plant Leaves; Polyphenols; Pyruvaldehyde; Tea | 2019 |
Oral administration of green tea Epigallocatechin-3-gallate reduces oxidative stress and enhances restoration of cardiac function in diabetic rats receiving autologous transplantation of adipose-derived stem cells.
Topics: Adipocytes; Adipose Tissue; Administration, Oral; Animals; Blood Glucose; Cardiomyopathies; Catechin; Diabetes Mellitus, Experimental; Echocardiography; Inflammation; Male; Oxidative Stress; Rats; Rats, Wistar; Stem Cell Transplantation; Stem Cells; Tea; Transplantation, Autologous | 2021 |
Epigallocatechin-3-gallate enhances the osteoblastogenic differentiation of human adipose-derived stem cells.
Topics: Adipocytes; Adult; Catechin; Cell Proliferation; Dose-Response Relationship, Drug; Female; Humans; Osteogenesis; Stem Cells; Structure-Activity Relationship; Tea | 2019 |
Enhanced Antiarthritic Efficacy by Nanoparticles of (-)-Epigallocatechin Gallate-Glucosamine-Casein.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Caseins; Catechin; Cytokines; Drug Carriers; Drug Compounding; Female; Glucosamine; Humans; Nanoparticles; Rats; Rats, Wistar | 2019 |
Cardiogenesis impairment promoted by bisphenol A exposure is successfully counteracted by epigallocatechin gallate.
Topics: Acetylation; Animals; Benzhydryl Compounds; Catechin; Endocrine Disruptors; Epigenesis, Genetic; Estrogens; Histones; Organogenesis; Phenols; Receptors, Estrogen; Zebrafish | 2019 |
Effect of epigallocatechin gallate on the gelatinisation and retrogradation of wheat starch.
Topics: Catechin; Gels; Hydrogen Bonding; Spectroscopy, Fourier Transform Infrared; Starch; Triticum; Viscosity; X-Ray Diffraction | 2019 |
Preparation and antioxidant activity of sodium alginate and carboxymethyl cellulose edible films with epigallocatechin gallate.
Topics: Alginates; Antioxidants; Carboxymethylcellulose Sodium; Catechin; Chemical Phenomena; Food Packaging; Free Radicals; Mechanical Phenomena; Membranes, Artificial; Spectroscopy, Fourier Transform Infrared | 2019 |
Phenolic Compounds from
Topics: Animals; Antioxidants; Biological Products; Biphenyl Compounds; Caenorhabditis elegans; Catechin; Flavonoids; Fluorescence Recovery After Photobleaching; Green Fluorescent Proteins; Oxidative Stress; Phenols; Picrates; Plant Extracts; Populus; Reactive Oxygen Species; Salix | 2019 |
Thermal cycling-hyperthermia in combination with polyphenols, epigallocatechin gallate and chlorogenic acid, exerts synergistic anticancer effect against human pancreatic cancer PANC-1 cells.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Chlorogenic Acid; Combined Modality Therapy; Drug Synergism; Humans; Hyperthermia, Induced; Mitochondria; Pancreatic Neoplasms; Polyphenols | 2019 |
White tea - A cost effective alternative to EGCG in fight against benzo(a)pyrene (BaP) induced lung toxicity in SD rats.
Topics: Animals; Benzo(a)pyrene; Biomarkers; Camellia sinensis; Catechin; Citrulline; Female; Free Radical Scavengers; Inflammation; Lipid Peroxidation; Lung; Lung Injury; Nitric Oxide; Oxidative Stress; Plant Extracts; Protein Carbonylation; Rats, Sprague-Dawley; Reactive Oxygen Species; Tea | 2019 |
The therapeutic potential of epigallocatechin‑3‑gallate against human oral squamous cell carcinoma through inhibition of cell proliferation and induction of apoptosis: In vitro and in vivo murine xenograft study.
Topics: Animals; Apoptosis; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Cell Proliferation; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Mouth Neoplasms; Xenograft Model Antitumor Assays | 2019 |
Unveiling the activating mechanism of tea residue for boosting the biological decolorization performance of refractory dye.
Topics: Anthraquinones; Bacteria; Biodegradation, Environmental; Catechin; Coloring Agents; Sewage; Tea; Waste Products | 2019 |
Epigallocatechin-3-Gallate Prevents Acute Gout by Suppressing NLRP3 Inflammasome Activation and Mitochondrial DNA Synthesis.
Topics: Animals; Caspase 1; Catechin; Disease Models, Animal; DNA, Mitochondrial; Gout; Humans; Inflammasomes; Inflammation; Interleukin-1beta; Macrophages; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Reactive Oxygen Species; Uric Acid | 2019 |
Epigallocatechin-3-gallate (EGCG) exert therapeutic effect on acute inflammatory otitis media in rats.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Catechin; Down-Regulation; Drug Therapy, Combination; Gene Expression; Interleukin-1beta; Lipopolysaccharides; Male; Otitis Media; Penicillin G; Random Allocation; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Tympanic Membrane | 2019 |
Spectroscopic and cytotoxicity studies on the combined interaction of (-)-epigallocatechin-3-gallate and anthracycline drugs with human serum albumin.
Topics: Anthracyclines; Antibiotics, Antineoplastic; Anticarcinogenic Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Catechin; Cell Survival; Circular Dichroism; Doxorubicin; Entropy; Epirubicin; HeLa Cells; Humans; Neoplasms; Protein Binding; Serum Albumin, Human; Spectrometry, Fluorescence | 2019 |
(‑)‑Epigallocatechin‑3‑gallate inhibits bladder cancer stem cells via suppression of sonic hedgehog pathway.
Topics: Biomarkers, Tumor; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Humans; Neoplastic Stem Cells; Signal Transduction; Urinary Bladder Neoplasms | 2019 |
(-)-Epigallocatechin-3-gallate and hydroxytyrosol improved antioxidative and anti-inflammatory responses in bovine mammary epithelial cells.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Catechin; Cattle; Cell Line; Epithelial Cells; Phenylethyl Alcohol | 2019 |
Co-Delivery of Natural Compounds with a Dual-Targeted Nanoparticle Delivery System for Improving Synergistic Therapy in an Orthotopic Tumor Model.
Topics: Animals; Catechin; Curcumin; Drug Delivery Systems; Humans; Hyaluronan Receptors; Male; Mice; Mice, SCID; Neoplasm Proteins; Neoplasms, Experimental; P-Selectin; PC-3 Cells; Prostatic Neoplasms; Xenograft Model Antitumor Assays | 2019 |
Comparative proteomics reveals concordant and discordant biochemical effects of caffeine versus epigallocatechin-3-gallate in human endothelial cells.
Topics: Caffeine; Catechin; Cells, Cultured; Down-Regulation; Endothelial Cells; Humans; Proteomics; RNA, Messenger; Tea; Transcriptional Activation | 2019 |
Curcumin as a permeability enhancer enhanced the antihyperlipidemic activity of dietary green tea extract.
Topics: Animals; Antioxidants; Biological Availability; Catechin; Curcumin; Drug Evaluation, Preclinical; Drug Synergism; Female; Hyperlipidemias; Male; Permeability; Phytotherapy; Rats, Sprague-Dawley; Tea | 2019 |
Pharmacokinetic, toxicokinetic, and bioavailability studies of epigallocatechin-3-gallate loaded solid lipid nanoparticle in rat model.
Topics: Administration, Oral; Animals; Biological Availability; Catechin; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Drug Evaluation, Preclinical; Drug Liberation; Lipids; Male; Models, Animal; Models, Chemical; Nanoparticles; Rats; Tissue Distribution; Toxicokinetics | 2019 |
QSAR modeling, pharmacophore-based virtual screening, and ensemble docking insights into predicting potential epigallocatechin gallate (EGCG) analogs against epidermal growth factor receptor.
Topics: Catechin; Computer Simulation; ErbB Receptors; Humans; Ligands; Models, Molecular; Molecular Docking Simulation; Protein Binding; Protein Conformation; Protein Kinase Inhibitors; Quantitative Structure-Activity Relationship; Signal Transduction | 2019 |
Oligomeric proanthocyanidins and epigallocatechin gallate aggravate autophagy of foam cells through the activation of Class III PI3K/Beclin1-complex mediated cholesterol efflux.
Topics: ATP Binding Cassette Transporter 1; Autophagy; Autophagy-Related Protein 5; Beclin-1; Catechin; Cholesterol; Chromones; Class III Phosphatidylinositol 3-Kinases; Enzyme Inhibitors; Foam Cells; Gene Expression Regulation; Humans; Microtubule-Associated Proteins; Morpholines; Phagosomes; Proanthocyanidins; Protein Isoforms; Proto-Oncogene Proteins c-akt; Signal Transduction; THP-1 Cells; TOR Serine-Threonine Kinases | 2019 |
Epigallocatechin-3-gallate ameliorates lipopolysaccharide-induced acute lung injury by suppression of TLR4/NF-κB signaling activation.
Topics: Acute Lung Injury; Animals; Catechin; Disease Models, Animal; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Signal Transduction; Toll-Like Receptor 4 | 2019 |
Colloidal (-)-epigallocatechin-3-gallate vesicular systems for prevention and treatment of skin cancer: A comprehensive experimental study with preclinical investigation.
Topics: Animals; Catechin; Cell Line, Tumor; Colloids; Drug Carriers; Humans; Lecithins; Male; Mice, Inbred BALB C; Mice, Nude; Polysorbates; Skin Neoplasms | 2019 |
Protective effect of green tea catechin against urban fine dust particle-induced skin aging by regulation of NF-κB, AP-1, and MAPKs signaling pathways.
Topics: Catechin; Cell Line; Collagenases; Dust; Fibroblasts; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase Inhibitors; NF-kappa B; Pancreatic Elastase; Particulate Matter; Reactive Oxygen Species; Skin; Skin Aging; Tea; Transcription Factor AP-1 | 2019 |
Differences in chemical composition predictive of in vitro biological activity among commercially important cultivars of genus Camellia.
Topics: Camellia; Camellia sinensis; Catechin; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Food Analysis; Humans; Metabolome; Plant Extracts; Plant Leaves; Principal Component Analysis; Tandem Mass Spectrometry; Tea | 2019 |
Monitoring Insulin-Aggregated Structures in the Presence of Epigallocatechin-3-gallate and Melatonin by Molecular Dynamics Simulations.
Topics: Catechin; Insulin; Melatonin; Models, Chemical; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure | 2019 |
Inhibition by Epigallocatechin Gallate of IL-1-Induced Urokinase-Type Plasminogen Activator Expression and Collagen Degradation by Corneal Fibroblasts.
Topics: Antioxidants; Catechin; Cell Survival; Cells, Cultured; Collagen; Corneal Keratocytes; Dose-Response Relationship, Drug; Fibrin; Fibrinolysin; Gene Expression Regulation; Humans; Hydroxyproline; Interleukin-1beta; Matrix Metalloproteinase 1; NF-kappa B; Real-Time Polymerase Chain Reaction; Urokinase-Type Plasminogen Activator | 2019 |
Simultaneous determination of the pharmacokinetics of A-type EGCG and ECG dimers in mice plasma and its metabolites by UPLC-QTOF-MS.
Topics: Animals; Catechin; Chromatography, Liquid; Dimerization; Half-Life; Injections, Intravenous; Mass Spectrometry; Mice | 2020 |
Neuroprotection in multiple system atrophy: unresolved issues.
Topics: Catechin; Double-Blind Method; Humans; Multiple System Atrophy; Neuroprotection | 2019 |
Different inhibition properties of catechins on the individual subunits of mucosal α-glucosidases as measured by partially-purified rat intestinal extract.
Topics: alpha-Amylases; alpha-Glucosidases; Animals; Blood Glucose; Carbohydrate Metabolism; Catechin; Glucose; Hydroxybenzoates; Intestines; Mucous Membrane; Rats; Starch; Substrate Specificity | 2019 |
Untargeted metabolomics coupled with chemometrics analysis reveals potential non-volatile markers during oolong tea shaking.
Topics: Catechin; Chromatography, High Pressure Liquid; Databases, Factual; Food Quality; Glutamates; Metabolomics; Phenylalanine; Plant Leaves; Proline; Tea; Tryptophan; Volatile Organic Compounds | 2019 |
Positive Effects of the Tea Catechin, (-)-Epigallocatechin-3-Gallate, on Gut Prophenoloxidase and the Survival of Ectropis obliqua (Lepidoptera: Geometridae).
Topics: Animals; Catechin; Catechol Oxidase; China; Enzyme Precursors; Moths; Tea | 2019 |
Enhancing skin penetration of epigallocatechin gallate by modifying partition coefficient using reverse micelle method.
Topics: Administration, Cutaneous; Animals; Catechin; Cell Survival; Drug Carriers; HeLa Cells; Hexoses; Humans; Hydrophobic and Hydrophilic Interactions; Male; Micelles; Polysorbates; Rats; Rats, Wistar; Skin | 2019 |
A Generic Coordination Assembly-Enabled Nanocoating of Individual Tumor Cells for Personalized Immunotherapy.
Topics: Animals; Antigens; Body Weight; Bone Marrow Cells; Catechin; Cell Line, Tumor; Cell Survival; Dendritic Cells; Female; Humans; Immunotherapy; Lung Neoplasms; Mice, Inbred C57BL; Nanoparticles; Neoplasms; Photoelectron Spectroscopy; Precision Medicine | 2019 |
Glucosylation of flavonoids and flavonoid glycosides by mutant dextransucrase from Lactobacillus reuteri TMW 1.106.
Topics: Anthocyanins; Bacterial Proteins; Catechin; Flavonoids; Glucosides; Glucosyltransferases; Glycosides; Glycosylation; Limosilactobacillus reuteri; Magnetic Resonance Spectroscopy; Molecular Structure; Mutation; Quercetin; Rutin | 2019 |
Inhibitory Effect of Epigallocatechin Gallate, Epigallocatechin, and Gallic Acid on the Formation of N-Nitrosodiethylamine In Vitro.
Topics: Catechin; Diethylnitrosamine; Free Radicals; Gallic Acid; Kinetics; Phenols | 2019 |
Melatonin and (-)-Epigallocatechin-3-Gallate: Partners in Fighting Cancer.
Topics: Anticarcinogenic Agents; Catechin; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p21; Hep G2 Cells; Humans; Melatonin; Neoplasms | 2019 |
Usage of and attitudes about green tea extract and Epigallocathechin-3-gallate (EGCG) as a therapy in individuals with Down syndrome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Attitude; Caregivers; Catechin; Cross-Sectional Studies; Dietary Supplements; Down Syndrome; Female; Humans; Male; Middle Aged; Plant Extracts; Tea; Young Adult | 2019 |
Epigallocatechin gallate attenuates arsenic induced genotoxicity via regulation of oxidative stress in balb/C mice.
Topics: Animals; Antioxidants; Apoptosis; Arsenic; Arsenic Poisoning; Catechin; DNA Damage; Female; Mice; Mice, Inbred BALB C; Mutagenicity Tests; Oxidative Stress; Reactive Oxygen Species; Signal Transduction | 2019 |
Gly45 and Phe555 in Transmembrane Domains 1 and 10 Are Critical for the Activation of Organic Anion Transporting Polypeptide 1B3 by Epigallocatechin Gallate.
Topics: Amino Acid Motifs; Camellia sinensis; Catechin; HEK293 Cells; Humans; Kinetics; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Plant Extracts; Protein Domains; Solute Carrier Organic Anion Transporter Family Member 1B3 | 2019 |
Evaluation of (-)-epigallocatechin-3-gallate (EGCG)-induced cytotoxicity on astrocytes: A potential mechanism of calcium overloading-induced mitochondrial dysfunction.
Topics: Animals; Apoptosis; Astrocytes; Calcium; Catechin; Cell Proliferation; Cells, Cultured; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Reactive Oxygen Species | 2019 |
Identification of the Catechin Uptake Transporter Responsible for Intestinal Absorption of Epigallocatechin Gallate in Mice.
Topics: Animals; Antioxidants; Biological Availability; Biological Transport; Catechin; Intestinal Absorption; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Tea; Xenopus laevis | 2019 |
Low dose Epigallocatechin Gallate Alleviates Experimental Colitis by Subduing Inflammatory Cells and Cytokines, and Improving Intestinal Permeability.
Topics: Animals; Anti-Inflammatory Agents; Catechin; Colitis; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Agents; Inflammation Mediators; Macrophages; Male; Mice, Inbred C57BL; Permeability; T-Lymphocytes | 2019 |
Hydrophobic Interactions Drive Binding between Vascular Endothelial Growth Factor-A (VEGFA) and Polyphenolic Inhibitors.
Topics: Catechin; Cell Proliferation; Circular Dichroism; Flavonoids; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Neovascularization, Pathologic; Polyphenols; Protein Binding; Protein Structure, Secondary; Signal Transduction; Surface Plasmon Resonance; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2019 |
Desmin forms toxic, seeding-competent amyloid aggregates that persist in muscle fibers.
Topics: Amyloid; Animals; Catechin; Desmin; Humans; Mice; Muscle Fibers, Skeletal; Mutation; Protein Aggregates | 2019 |
Anti-osteoclastogenic effect of epigallocatechin gallate-functionalized gold nanoparticles in vitro and in vivo.
Topics: Animals; Bone Marrow Cells; Bone Resorption; Catechin; Cell Death; Density Functional Theory; Down-Regulation; Drug Liberation; Drug Stability; Gold; Ligands; Lipopolysaccharides; Macrophages; Male; Metal Nanoparticles; Mice, Inbred BALB C; Models, Biological; Osteogenesis; RANK Ligand; Reactive Oxygen Species; Signal Transduction; Skull; Transcription, Genetic | 2019 |
Epigallocatechin-3-Gallate Attenuates Microglial Inflammation and Neurotoxicity by Suppressing the Activation of Canonical and Noncanonical Inflammasome via TLR4/NF-κB Pathway.
Topics: Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Humans; Inflammasomes; Inflammation; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Neuroprotective Agents; Neurotoxicity Syndromes; NF-kappa B; Rats; Rats, Sprague-Dawley; Toll-Like Receptor 4 | 2019 |
Enhanced anti-colon cancer efficacy of 5-fluorouracil by epigallocatechin-3- gallate co-loaded in wheat germ agglutinin-conjugated nanoparticles.
Topics: Animals; Apoptosis; Catechin; Colonic Neoplasms; Fluorouracil; HT29 Cells; Humans; Mice; Nanoconjugates; Neovascularization, Pathologic; Wheat Germ Agglutinins; Xenograft Model Antitumor Assays | 2019 |
DNA-templated porous nanoplatform towards programmed "double-hit" cancer therapy via hyperthermia and immunogenicity activation.
Topics: Animals; Catechin; Cobalt; DNA; Drug Delivery Systems; Drug Liberation; HCT116 Cells; HSP90 Heat-Shock Proteins; Humans; Hyperthermia, Induced; Magnetic Resonance Imaging; Mice; Nanoparticles; Neoplasms; Oxaliplatin; Phototherapy; Porosity; Tissue Distribution | 2019 |
Interaction between an (-)-epigallocatechin-3-gallate-copper complex and bovine serum albumin: Fluorescence, circular dichroism, HPLC, and docking studies.
Topics: Binding, Competitive; Catechin; Chromatography, High Pressure Liquid; Circular Dichroism; Coordination Complexes; Copper; Ligands; Molecular Docking Simulation; Protein Structure, Secondary; Serum Albumin, Bovine; Spectrometry, Fluorescence | 2019 |
Development of broccoli by-products as carriers for delivering EGCG.
Topics: Adsorption; Antioxidants; Brassica; Catechin; Digestion; Drug Carriers; Drug Delivery Systems; Spectroscopy, Fourier Transform Infrared; Waste Products | 2019 |
Binding characteristics of polyphenols as milk plasmin inhibitors.
Topics: Animals; Antifibrinolytic Agents; Camellia sinensis; Catechin; Cattle; Fibrinolysin; Kinetics; Milk; Plant Extracts; Polyphenols | 2019 |
The Inhibitory Effect of (-)-Epigallocatechin-3-Gallate on Breast Cancer Progression via Reducing
Topics: Adaptor Proteins, Signal Transducing; Breast Neoplasms; Calcium-Binding Proteins; Catechin; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Neoplasm Proteins | 2019 |
Epigallocatechin-3-Gallate (EGCG) Suppresses Pancreatic Cancer Cell Growth, Invasion, and Migration partly through the Inhibition of Akt Pathway and Epithelial-Mesenchymal Transition: Enhanced Efficacy when Combined with Gemcitabine.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Deoxycytidine; Enzyme Stability; Epithelial-Mesenchymal Transition; Gemcitabine; Humans; Mice, Inbred C57BL; Neoplasm Invasiveness; Pancreatic Neoplasms; Proteolysis; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Burden | 2019 |
Epigallocatechin-3-Gallate Reduces Hepatic Oxidative Stress and Lowers CYP-Mediated Bioactivation and Toxicity of Acetaminophen in Rats.
Topics: Acetaminophen; Animals; Catechin; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Liver; Oxidative Stress; Polyphenols; Rats; Tea | 2019 |
Antioxidant Activity and Main Chemical Components of a Novel Fermented Tea.
Topics: Antioxidants; Biflavonoids; Biphenyl Compounds; Camellia sinensis; Catechin; Color; Fermentation; Flavonoids; Gallic Acid; gamma-Aminobutyric Acid; Humans; Hydroxyl Radical; Odorants; Picrates; Taste; Tea | 2019 |
Protective Role of Epigallocatechin Gallate in a Rat Model of Cisplatin-Induced Cerebral Inflammation and Oxidative Damage: Impact of Modulating NF-κB and Nrf2.
Topics: Animals; Antineoplastic Agents; Catechin; Cerebral Cortex; Cisplatin; Inflammation Mediators; Male; Models, Animal; Neuroprotective Agents; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar | 2020 |
Geographical origin traceability of Keemun black tea based on its non-volatile composition combined with chemometrics.
Topics: Biflavonoids; Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Discriminant Analysis; Gallic Acid; Models, Statistical; Principal Component Analysis; Tea | 2019 |
Complex of EGCG with Cu(II) Suppresses Amyloid Aggregation and Cu(II)-Induced Cytotoxicity of α-Synuclein.
Topics: alpha-Synuclein; Amyloidogenic Proteins; Animals; Catechin; Cell Line; Copper; Neuroprotective Agents; Nuclear Magnetic Resonance, Biomolecular; Oxidative Stress; Parkinson Disease; Protein Aggregates; Protein Aggregation, Pathological; Rats; Reactive Oxygen Species | 2019 |
Restoring the activity of the antibiotic aztreonam using the polyphenol epigallocatechin gallate (EGCG) against multidrug-resistant clinical isolates of
Topics: Animals; Anti-Bacterial Agents; Aztreonam; Catechin; Drug Resistance, Multiple, Bacterial; Drug Synergism; Humans; Larva; Microbial Sensitivity Tests; Moths; Polyphenols; Pseudomonas aeruginosa; Pseudomonas Infections | 2019 |
Synergetic Effect of EP1 Receptor Antagonist and (-)-Epigallocatechin-3-gallate in Hepatocellular Carcinoma.
Topics: Alprostadil; Apoptosis; Carcinoma, Hepatocellular; Catechin; Cell Movement; Cell Proliferation; Dinoprostone; Drug Synergism; Hep G2 Cells; Humans; Liver Neoplasms; Receptors, Prostaglandin E, EP1 Subtype; Wound Healing | 2019 |
Comparison of antiproliferative effect of epigallocatechin gallate when loaded into cationic solid lipid nanoparticles against different cell lines.
Topics: Anticarcinogenic Agents; Caco-2 Cells; Catechin; Cations; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Hep G2 Cells; Humans; Inhibitory Concentration 50; Lipids; MCF-7 Cells; Nanoparticles | 2019 |
Antioxidant and Pro-Oxidant Activities of Melatonin in the Presence of Copper and Polyphenols In Vitro and In Vivo.
Topics: Animals; Antioxidants; Catechin; Chelating Agents; Copper; DNA Damage; Male; Melatonin; Mice; Quercetin; Reactive Oxygen Species | 2019 |
Insight into the inactivation mechanism of soybean Bowman-Birk trypsin inhibitor (BBTI) induced by epigallocatechin gallate and epigallocatechin: Fluorescence, thermodynamics and docking studies.
Topics: Catechin; Fluorescence; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Protein Conformation; Thermodynamics; Trypsin Inhibitor, Bowman-Birk Soybean | 2020 |
Biochemical and computational insights of adenosine deaminase inhibition by Epigallocatechin gallate.
Topics: Adenosine Deaminase; Adenosine Deaminase Inhibitors; Calorimetry; Camellia sinensis; Catechin; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Spectrometry, Fluorescence; Thermodynamics | 2019 |
Fabrication of (-)-epigallocatechin-3-gallate carrier based on glycosylated whey protein isolate obtained by ultrasound Maillard reaction.
Topics: Catechin; Glycosylation; Hydrophobic and Hydrophilic Interactions; Maillard Reaction; Ultrasonic Waves; Whey Proteins | 2019 |
Dietary supplementation of a high-temperature-processed green tea extract attenuates cognitive impairment in PS2 and Tg2576 mice.
Topics: Amyloid beta-Peptides; Animals; Camellia sinensis; Catechin; Cognition Disorders; Dietary Supplements; Hot Temperature; Mice; Mice, Transgenic; PC12 Cells; Plant Extracts; Presenilin-2; Rats | 2019 |
Improved in vitro antioxidant properties and hepatoprotective effects of a fermented Inula britannica extract on ethanol-damaged HepG2 cells.
Topics: Alanine Transaminase; Antioxidants; Aspartate Aminotransferases; Catechin; Chemical and Drug Induced Liver Injury; Ethanol; Fermentation; Hep G2 Cells; Humans; Inula; Liver; Plant Extracts | 2019 |
Effect of sodium alginate and carboxymethyl cellulose edible coating with epigallocatechin gallate on quality and shelf life of fresh pork.
Topics: Alginates; Carboxymethylcellulose Sodium; Catechin; Food Preservation; Food Preservatives; Pork Meat | 2019 |
Influence of green tea extract in the color of composite resin restorations.
Topics: Adhesives; Bisphenol A-Glycidyl Methacrylate; Catechin; Coffee; Color; Composite Resins; Dental Caries; Dental Restoration Failure; Dental Restoration, Permanent; Dentin; Dentin-Bonding Agents; Humans; Materials Testing; Molar; Resin Cements; Surface Properties; Tea | 2019 |
Multilevel structure-activity profiling reveals multiple green tea compound families that each modulate ubiquitin-activating enzyme and ubiquitination by a distinct mechanism.
Topics: Catechin; Flavonoids; HEK293 Cells; Humans; Proliferating Cell Nuclear Antigen; Structure-Activity Relationship; Tea; Ubiquitin-Activating Enzymes; Ubiquitination | 2019 |
EGCG enhances cancer cells sensitivity under
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Catechin; Cell Line, Tumor; Cobalt Radioisotopes; Down-Regulation; Gamma Rays; Mice; MicroRNAs; Proto-Oncogene Proteins c-bcl-2; Radiation-Protective Agents; Radiation-Sensitizing Agents; Signal Transduction; Sirtuin 1; Tumor Suppressor Protein p53; Up-Regulation | 2019 |
Cerebral protection of epigallocatechin gallate (EGCG) via preservation of mitochondrial function and ERK inhibition in a rat resuscitation model.
Topics: Animals; Cardiopulmonary Resuscitation; Catechin; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Heart Arrest; Male; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley | 2019 |
Effect of EGCG-gelatin biofilm on the quality and microbial composition of tilapia fillets during chilled storage.
Topics: Aeromonas; Animals; Biogenic Amines; Biomimetic Materials; Catechin; Food Storage; Gelatin; Lipid Peroxidation; Protein Denaturation; Proteins; Pseudomonas; Seafood; Taste; Temperature | 2020 |
Mitigative effects of epigallocatechin gallate in terms of diminishing apoptosis and oxidative stress generated by the combination of lead and amyloid peptides in human neuronal cells.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Annexin A5; Apoptosis; bcl-2-Associated X Protein; Camellia sinensis; Caspase 3; Catechin; Cell Cycle; Cell Line, Tumor; Cell Survival; Humans; Lead; Neurons; Neuroprotective Agents; Oxidative Stress; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species | 2019 |
Utilizing the Combination of Binding Kinetics and Micro-Pharmacokinetics Link in Vitro α-Glucosidase Inhibition to in Vivo Target Occupancy.
Topics: alpha-Glucosidases; Animals; Catechin; Glycoside Hydrolase Inhibitors; Intestinal Absorption; Models, Biological; Rats; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2019 |
Epigallocatechin-3-gallate (EGCG) inhibits aggregation of pulmonary fibrosis associated mutant surfactant protein A2 via a proteasomal degradation pathway.
Topics: Animals; Butylamines; Catechin; CHO Cells; Cricetulus; Cysteine Proteinase Inhibitors; Detergents; Gene Expression; Leupeptins; Mutation; Octoxynol; Proteasome Endopeptidase Complex; Protein Aggregates; Protein Stability; Proteolysis; Pulmonary Fibrosis; Pulmonary Surfactant-Associated Protein A; Recombinant Proteins; Solubility | 2019 |
ERK1/2-HNF4α axis is involved in epigallocatechin-3-gallate inhibition of HBV replication.
Topics: Animals; Antiviral Agents; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation, Viral; Hep G2 Cells; Hepatitis B; Hepatitis B virus; Hepatocyte Nuclear Factor 4; Humans; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Virus Replication | 2020 |
Epigallocatechin-3-gallate downregulates lipopolysaccharide signaling in human aortic endothelial cells by inducing ectodomain shedding of TLR4.
Topics: ADAM10 Protein; Aorta; Calcium; Catechin; Cytosol; Down-Regulation; Endothelial Cells; Extracellular Space; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Lipopolysaccharides; Protein Domains; Signal Transduction; Toll-Like Receptor 4 | 2019 |
Divergent Roles of Kupffer Cell TLR2/3 Signaling in Alcoholic Liver Disease and the Protective Role of EGCG.
Topics: Animals; Catechin; Disease Progression; Ethanol; Humans; Interleukin-10; Kupffer Cells; Liver; Liver Diseases, Alcoholic; Male; Mice; Mice, Knockout; Protective Agents; Toll-Like Receptor 2; Toll-Like Receptor 3 | 2020 |
Fabrication of surface-active antioxidant biopolymers by using a grafted scallop (Patinopecten yessoensis) gonad protein isolate-epigallocatechin gallate (EGCG) conjugate: improving the stability of tuna oil-loaded emulsions.
Topics: Animals; Antioxidants; Biopolymers; Catechin; Circular Dichroism; Emulsifying Agents; Emulsions; Fatty Acids; Fish Oils; Fish Proteins; Free Radicals; Gonads; Lipid Metabolism; Oxidation-Reduction; Pectinidae; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tuna | 2019 |
A glycated whey protein isolate-epigallocatechin gallate nanocomplex enhances the stability of emulsion delivery of β-carotene during simulated digestion.
Topics: beta Carotene; Catechin; Digestion; Drug Delivery Systems; Emulsions; Hydrophobic and Hydrophilic Interactions; Lipolysis; Nanoparticles; Pancreatin; Particle Size; Triglycerides; Whey Proteins | 2019 |
Epigallocatechin-3-O-gallate induces acid sphingomyelinase activation through activation of phospholipase C.
Topics: Apoptosis; Catechin; Cell Line, Tumor; Cyclic GMP; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Multiple Myeloma; Phosphorylation; Signal Transduction; Sphingomyelin Phosphodiesterase; Type C Phospholipases | 2019 |
Beneficial effects of green tea on age related diseases.
Topics: Aging; Camellia sinensis; Catechin; Diabetes Mellitus, Type 2; Functional Food; Humans; Metabolic Syndrome; Obesity; Plant Extracts; Tea | 2020 |
Epigallocatechin-3-gallate inhibits tumor angiogenesis: involvement of endoglin/Smad1 signaling in human umbilical vein endothelium cells.
Topics: Angiogenesis Inhibitors; Catechin; Cell Movement; Cell Proliferation; Cells, Cultured; Endoglin; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Neoplasm Invasiveness; Neovascularization, Pathologic; Pyrroles; Signal Transduction; Smad1 Protein; Vascular Endothelial Growth Factor A | 2019 |
Lipid Membranes Influence the Ability of Small Molecules To Inhibit Huntingtin Fibrillization.
Topics: Amyloidogenic Proteins; Catechin; Curcumin; Humans; Huntingtin Protein; Liposomes; Phosphatidylcholines; Protein Multimerization | 2019 |
Co-encapsulation of Epigallocatechin Gallate (EGCG) and Curcumin by Two Proteins-Based Nanoparticles: Role of EGCG.
Topics: Biological Availability; Caseins; Catechin; Curcumin; Drug Compounding; Gastrointestinal Tract; Humans; Hydrophobic and Hydrophilic Interactions; Models, Biological; Nanoparticles; Particle Size; Zein | 2019 |
Green Tea Polyphenol (-)-Epigallocatechin Gallate (EGCG) Attenuates Neuroinflammation in Palmitic Acid-Stimulated BV-2 Microglia and High-Fat Diet-Induced Obese Mice.
Topics: Animals; Anti-Obesity Agents; Catechin; Cell Line; Diet, High-Fat; Disease Models, Animal; Hypothalamus; Inflammation; Interleukin-1beta; Interleukin-6; Janus Kinase 2; Lipid Metabolism; Mice; Mice, Inbred C57BL; Mice, Obese; Microglia; Obesity; Palmitic Acid; Polyphenols; STAT3 Transcription Factor; Tea; Tumor Necrosis Factor-alpha | 2019 |
Role and mechanism of catechin in skeletal muscle cell differentiation.
Topics: Animals; Catechin; Cell Differentiation; Cell Line; Elastic Modulus; Gene Expression Regulation; Mice; Microscopy, Atomic Force; Muscle Fibers, Skeletal; Muscle, Skeletal; Myoblasts, Skeletal; MyoD Protein; Myogenin | 2019 |
Conjugation Of EGCG And Chitosan NPs As A Novel Nano-Drug Delivery System.
Topics: Catechin; Chitosan; Drug Delivery Systems; Dynamic Light Scattering; Gold; Humans; Image Processing, Computer-Assisted; Metal Nanoparticles; Particle Size; Photoelectron Spectroscopy; Spectroscopy, Fourier Transform Infrared | 2019 |
Evidence of noncovalent complexes in some natural extracts: Ceylon tea and mate extracts.
Topics: Biflavonoids; Caffeine; Camellia sinensis; Catechin; Chlorogenic Acid; Chromatography, Liquid; Ilex paraguariensis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plant Extracts; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tea | 2020 |
Translating In Vitro Acrolein-Trapping Capacities of Tea Polyphenol and Soy Genistein to In Vivo Situation is Mediated by the Bioavailability and Biotransformation of Individual Polyphenols.
Topics: Acrolein; Animals; Biological Availability; Catechin; Genistein; Glycine max; Magnetic Resonance Spectroscopy; Male; Mice; Polyphenols; Tea | 2020 |
Calorimetric approach for comparison of Angiopoietin-like protein 4 with other pancreatic lipase inhibitors.
Topics: Angiopoietin-Like Protein 4; Anti-Obesity Agents; Calorimetry; Catechin; Drug Evaluation, Preclinical; Enzyme Assays; Humans; Lipase; Obesity; Orlistat; Polylysine; Recombinant Proteins | 2020 |
Protective effects of epigallocatechin gallate against ischemia reperfusion injury in rat skeletal muscle via activating Nrf2/HO-1 signaling pathway.
Topics: Activation, Metabolic; Animals; Antioxidants; Apoptosis; Catechin; Cytokines; Heme Oxygenase (Decyclizing); Male; Muscle, Skeletal; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction | 2019 |
Synergistic Chemical and Photodynamic Antimicrobial Therapy for Enhanced Wound Healing Mediated by Multifunctional Light-Responsive Nanoparticles.
Topics: Animals; Anti-Infective Agents; Catechin; Cell Line; Chlorophyllides; Delayed-Action Preparations; Escherichia coli; Magnesium; Mice; Nanoparticles; Photochemotherapy; Porphyrins; Rats; Staphylococcal Infections; Staphylococcus aureus; Wound Healing; Wound Infection | 2019 |
Plant Polyphenols Inhibit Functional Amyloid and Biofilm Formation in
Topics: Amyloid; Biofilms; Catechin; Fungal Proteins; Hydrolyzable Tannins; Polyphenols; Protein Aggregates; Pseudomonas | 2019 |
Phenolic compounds are less degraded in presence of starch than in presence of proteins through processing in model porridges.
Topics: Catechin; Food Handling; Gallic Acid; Gelatin; Phenols; Proteins; Starch | 2020 |
(-)-Epigallocatechin-3-gallate encapsulated realgar nanoparticles exhibit enhanced anticancer therapeutic efficacy against acute promyelocytic leukemia.
Topics: Antineoplastic Agents; Calorimetry, Differential Scanning; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Carriers; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Nanomedicine; Nanoparticles; Particle Size | 2019 |
Photoprotective effects of 2S,3R-6-methoxycarbonylgallocatechin isolated from Anhua dark tea on UVB-induced inflammatory responses in human keratinocytes.
Topics: Binding Sites; Catechin; Cell Differentiation; Cell Line; Cell Survival; Coculture Techniques; Cytokines; Humans; Keratinocytes; Macrophages; NF-E2-Related Factor 2; Protein Structure, Tertiary; Radiation-Protective Agents; Reactive Oxygen Species; Signal Transduction; STAT1 Transcription Factor; Tea; Ultraviolet Rays | 2020 |
Prodrug of epigallocatechin-3-gallate alleviates choroidal neovascularization via down-regulating HIF-1α/VEGF/VEGFR2 pathway and M1 type macrophage/microglia polarization.
Topics: Animals; Catechin; Cell Polarity; Cells, Cultured; Choroidal Neovascularization; Down-Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Macrophages; Macular Degeneration; Male; Mice; Mice, Inbred C57BL; Microglia; Prodrugs; Signal Transduction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2020 |
(-)-Epigallocatechin gallate-loaded polycaprolactone scaffolds fabricated using a 3D integrated moulding method alleviate immune stress and induce neurogenesis.
Topics: Animals; Catechin; Cell Line; Muscle, Skeletal; Nerve Regeneration; Neurogenesis; Oxidative Stress; Peripheral Nervous System Diseases; Polyesters; Porosity; Radiation Injuries, Experimental; Rats; Schwann Cells; Sciatic Nerve; Tissue Scaffolds | 2020 |
Epigallocatechin 3-gallate attenuates arthritis by regulating Nrf2, HO-1, and cytokine levels in an experimental arthritis model.
Topics: Animals; Arthritis, Experimental; Catechin; Collagen Type II; Cytokines; Disease Models, Animal; Female; Heme Oxygenase (Decyclizing); NF-E2-Related Factor 2; Rats; Rats, Wistar | 2020 |
Effect of non-covalent and covalent complexation of (-)-epigallocatechin gallate with soybean protein isolate on protein structure and in vitro digestion characteristics.
Topics: Antioxidants; Catechin; Oxidation-Reduction; Particle Size; Polyphenols; Protein Stability; Protein Structure, Secondary; Soybean Proteins; Temperature | 2020 |
Vibrational (FT-IR, Raman) analysis of tea catechins based on both theoretical calculations and experiments.
Topics: Catechin; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Tea | 2020 |
Epigallocatechin-3-gallate prevents TGF-β1-induced epithelial-mesenchymal transition and fibrotic changes of renal cells via GSK-3β/β-catenin/Snail1 and Nrf2 pathways.
Topics: Animals; beta Catenin; Catechin; Dogs; Epithelial-Mesenchymal Transition; Fibronectins; Fibrosis; Glycogen Synthase Kinase 3 beta; Humans; Kidney; Madin Darby Canine Kidney Cells; Microscopy, Atomic Force; NF-E2-Related Factor 2; Phosphorylation; RNA, Small Interfering; Signal Transduction; Snail Family Transcription Factors; Transforming Growth Factor beta1 | 2020 |
A two-pronged anti-leukemic agent based on a hyaluronic acid-green tea catechin conjugate for inducing targeted cell death and terminal differentiation.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Catechin; Cell Death; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; HEK293 Cells; HL-60 Cells; Human Umbilical Vein Endothelial Cells; Humans; Hyaluronic Acid; Leukemia, Myeloid, Acute; Male; Mice; Xenograft Model Antitumor Assays | 2019 |
Study on Antioxidant Activity of Amino Acids at Frying Temperatures and Their Interaction with Rosemary Extract, Green Tea Extract, and Ascorbic Acid.
Topics: alpha-Tocopherol; Amino Acids; Antioxidants; Ascorbic Acid; Catechin; Cooking; Hot Temperature; Plant Extracts; Rosmarinus; Soybean Oil; Tea; Tocopherols | 2019 |
Oxidization increases the binding of EGCG to serum albumin revealed by kinetic data from label-free optical biosensor with reference channel.
Topics: Animals; Binding Sites; Biosensing Techniques; Catechin; Cattle; Humans; Interferometry; Kinetics; Oxidation-Reduction; Protein Binding; Serum Albumin; Serum Albumin, Bovine | 2020 |
Interaction of polyphenols with model membranes: Putative implications to mouthfeel perception.
Topics: Catechin; Liposomes; Membrane Lipids; Mouth Mucosa; Taste | 2020 |
Utilization of albumin fraction from defatted rice bran to stabilize and deliver (-)-epigallocatechin gallate.
Topics: Albumins; Antioxidants; Catechin; HT29 Cells; Humans; Interleukin-1beta; Mitogen-Activated Protein Kinase 14; NF-kappa B; Oryza; Particle Size; Transcriptional Activation | 2020 |
A mouse model of subacute liver failure with ascites induced by step-wise increased doses of (-)-epigallocatechin-3-gallate.
Topics: Acute Disease; Animals; Antioxidants; Apoptosis; Aquaporin 2; Ascites; Catechin; Disease Models, Animal; Kidney; Liver; Liver Failure; Male; Membrane Transport Proteins; Mice; Urea Transporters | 2019 |
Integration of Epigallocatechin Gallate in Gelatin Sponges Attenuates Matrix Metalloproteinase-Dependent Degradation and Increases Bone Formation.
Topics: Absorbable Implants; Aldehydes; Animals; Biocompatible Materials; Bone Regeneration; Bone Resorption; Catechin; Cell Line; Cell Proliferation; Gelatin; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Osteoblasts; Rats; Rats, Sprague-Dawley; Skull; Tissue Engineering; Tissue Scaffolds; X-Ray Microtomography | 2019 |
MicroRNA-384-5p/Beclin-1 As Potential Indicators For Epigallocatechin Gallate Against Cardiomyocytes Ischemia Reperfusion Injury By Inhibiting Autophagy Via PI3K/Akt Pathway.
Topics: Animals; Autophagy; Beclin-1; Catechin; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; HEK293 Cells; Humans; MicroRNAs; Molecular Structure; Myocardial Reperfusion Injury; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Structure-Activity Relationship | 2019 |
Seven-day Green Tea Supplementation Revamps Gut Microbiome and Caecum/Skin Metabolome in Mice from Stress.
Topics: Amino Acids; Animals; Bifidobacterium; Caffeine; Catechin; Cecum; Clostridium butyricum; Fatty Acids; Female; Glutamates; Lactobacillus; Metabolome; Mice; Microbiota; Plant Extracts; Prebiotics; Skin; Stress, Physiological; Tea; Ultraviolet Rays | 2019 |
Effects of Epigallocatechin Gallate (EGCG) on Urinary Bladder Urothelial Carcinoma-Next-Generation Sequencing and Bioinformatics Approaches.
Topics: Anticarcinogenic Agents; Carcinoma, Transitional Cell; Catechin; Cell Line, Tumor; Computational Biology; High-Throughput Nucleotide Sequencing; Humans; MicroRNAs; Signal Transduction; Urinary Bladder Neoplasms | 2019 |
Epigallocatechin-3-gallate modulates germ cell apoptosis through the SAFE/Nrf2 signaling pathway.
Topics: Animals; Apoptosis; Catechin; Germ Cells; Janus Kinase 2; Male; NF-E2-Related Factor 2; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Spermatogenesis; STAT1 Transcription Factor; STAT3 Transcription Factor; Testis | 2020 |
Antimicrobial Activity of, and Cellular Pathways Targeted by,
Topics: Anti-Bacterial Agents; Benzaldehydes; Catechin; Drug Resistance, Multiple, Bacterial; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 2020 |
Protective Effect of (-)Epigallocatechin-3-gallate on Rotenone-Induced Parkinsonism-like Symptoms in Rats.
Topics: Animals; Apoptosis; Behavior, Animal; Catechin; Corpus Striatum; Disease Models, Animal; Encephalitis; Inflammation Mediators; Male; Neuroprotective Agents; Parkinsonian Disorders; Rats, Wistar; Rotenone | 2020 |
Natural Moieties as Anti-Inflammatory Agents-Recent Patents.
Topics: Animals; Anti-Inflammatory Agents; Apigenin; Biological Products; Cardiovascular Diseases; Catechin; Coumaric Acids; Humans; Inflammation; Neoplasms; Neurodegenerative Diseases; Patents as Topic; Plants; Polyphenols; Quercetin | 2019 |
Epigallocatechin gallate inhibits leukotoxin release by Aggregatibacter actinomycetemcomitans by promoting association with the bacterial membrane.
Topics: Aggregatibacter actinomycetemcomitans; Animals; Bacteria; Bacterial Outer Membrane; Catechin; Exotoxins; Humans; Mice | 2020 |
Protective Effect of Epigallocatechin Gallate in Ischemia-Reperfusion Injury of Rat Skeletal Muscle.
Topics: Animals; Antioxidants; Catechin; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Kidney; Liver; Male; Muscle, Skeletal; Oxidative Stress; Rats; Reactive Oxygen Species; Reperfusion Injury | 2020 |
A Metal-Polyphenol-Coordinated Nanomedicine for Synergistic Cascade Cancer Chemotherapy and Chemodynamic Therapy.
Topics: Animals; Antineoplastic Agents; Catechin; Cisplatin; Hep G2 Cells; Humans; Mice; Nanomedicine; Nanoparticles; Neoplasms; Polyphenols; Prodrugs; Reactive Oxygen Species | 2020 |
The Environment Is a Key Factor in Determining the Anti-Amyloid Efficacy of EGCG.
Topics: Amyloidogenic Proteins; Catechin; Humans; Hydrogen-Ion Concentration | 2019 |
Radioprotection of EGCG based on immunoregulatory effect and antioxidant activity against
Topics: Animals; Antioxidants; Body Weight; Catechin; Cobalt Radioisotopes; Male; Mice; Monocytes; Organ Size; Oxidation-Reduction; Radiation Injuries, Experimental; Radiation-Protective Agents; Spleen | 2020 |
Epigallocatechin-3-Gallate (EGCG) Improves Cognitive Deficits Aggravated by an Obesogenic Diet Through Modulation of Unfolded Protein Response in APPswe/PS1dE9 Mice.
Topics: Amyloid beta-Peptides; Animals; Blood Glucose; Catechin; Cognitive Dysfunction; Diet, High-Fat; Hippocampus; Insulin; Liver; Male; Memory Disorders; Mice, Inbred C57BL; Mice, Obese; Mice, Transgenic; Models, Biological; Presenilin-1; Signal Transduction; Spatial Learning; Tissue Distribution; Unfolded Protein Response | 2020 |
Green tea polyphenol epigallocatechin-3-gallate improves the antioxidant capacity of eggs.
Topics: Animal Feed; Animals; Antioxidants; Catechin; Chickens; Dietary Supplements; Eggs; Female; Glutathione Transferase; Heme Oxygenase-1; NF-E2-Related Factor 2; Polyphenols | 2020 |
Polymer-Assisted In Situ Synthesis of Silver Nanoparticles with Epigallocatechin Gallate (EGCG) Impregnated Wound Patch Potentiate Controlled Inflammatory Responses for Brisk Wound Healing.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Bacillus subtilis; Bandages; Catechin; Escherichia coli; Galactans; Hydrogels; Mannans; Metal Nanoparticles; Plant Gums; Polymers; Rats, Wistar; Silver; Tensile Strength; Wound Healing | 2019 |
Epigallocatechin-3-gallate downregulates PDHA1 interfering the metabolic pathways in human herpesvirus 8 harboring primary effusion lymphoma cells.
Topics: Catechin; Cell Death; Cell Line, Tumor; Cell Survival; Down-Regulation; Glutarates; Herpesvirus 8, Human; Humans; Lymphoma, Primary Effusion; Metabolic Networks and Pathways; Pyruvate Dehydrogenase (Lipoamide) | 2020 |
Revealing the mechanisms of starch amylolysis affected by tea catechins using surface plasmon resonance.
Topics: alpha-Amylases; Camellia sinensis; Catechin; Humans; Kinetics; Plant Extracts; Protein Binding; Starch; Surface Plasmon Resonance; Tea | 2020 |
Green tea polyphenols and epigallocatechin-3-gallate protect against perfluorodecanoic acid induced liver damage and inflammation in mice by inhibiting NLRP3 inflammasome activation.
Topics: Animals; Antioxidants; Catechin; Decanoic Acids; Disease Models, Animal; Fluorocarbons; Inflammasomes; Inflammation; Liver Diseases; Male; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Polyphenols; Tea | 2020 |
SAHA and EGCG Promote Apoptosis in Triple-negative Breast Cancer Cells, Possibly Through the Modulation of cIAP2.
Topics: Apoptosis; Baculoviral IAP Repeat-Containing 3 Protein; Caspase 7; Catechin; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Triple Negative Breast Neoplasms; Vorinostat | 2020 |
Revealing the Mechanism of EGCG, Genistein, Rutin, Quercetin, and Silibinin Against hIAPP Aggregation via Computational Simulations.
Topics: Catechin; Diabetes Mellitus, Type 2; Genistein; Humans; Islet Amyloid Polypeptide; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Quercetin; Rutin; Silybin | 2020 |
The toxicity of non-aged and aged coated silver nanoparticles to the freshwater shrimp
Topics: Animals; Catechin; Curcumin; Decapoda; Metal Nanoparticles; Silver; Toxicity Tests; Tyrosine | 2019 |
Mainly Dimers and Trimers of Chinese Bayberry Leaves Proanthocyanidins (BLPs) are Utilized by Gut Microbiota: In Vitro Digestion and Fermentation Coupled with Caco-2 Transportation.
Topics: Biological Availability; Biopolymers; Caco-2 Cells; Catechin; Digestion; Fermentation; Gallic Acid; Gastric Mucosa; Gastrointestinal Microbiome; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Intestines; Myrica; Plant Leaves; Polymerization; Proanthocyanidins; Saliva | 2020 |
Targeting the heme protein hemoglobin by (-)-epigallocatechin gallate and the study of polyphenol-protein association using multi-spectroscopic and computational methods.
Topics: Animals; Catechin; Cattle; Hemoglobins; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Polyphenols; Protein Binding; Spectrum Analysis | 2020 |
Duo of (-)-epigallocatechin-3-gallate and doxorubicin loaded by polydopamine coating ZIF-8 in the regulation of autophagy for chemo-photothermal synergistic therapy.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Catechin; Doxorubicin; Female; HeLa Cells; Humans; Indoles; Mice; Mice, Nude; Phototherapy; Polymers; Reactive Oxygen Species; Tumor Cells, Cultured; Uterine Cervical Neoplasms; Zeolites | 2020 |
EGCG exerts its protective effect by mitigating the release of lysosomal enzymes in aged rat liver on exposure to high cholesterol diet.
Topics: Aging; Animals; Antioxidants; Catechin; Cholesterol, Dietary; Cytosol; Dietary Supplements; Hepatocytes; Immunohistochemistry; Lipids; Lipoproteins, LDL; Liver; Lysosomes; Male; Microscopy, Electron, Transmission; Oxidative Stress; Oxygen; Rats; Rats, Wistar | 2020 |
Analysis of inhibitory interaction between epigallocatechin gallate and alpha-glucosidase: A spectroscopy and molecular simulation study.
Topics: alpha-Glucosidases; Catechin; Glycoside Hydrolase Inhibitors; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Protein Binding; Protein Conformation; Saccharomyces cerevisiae; Thermodynamics | 2020 |
Effect of Green Tea Extract During Lactic Acid Bacteria Mediated Fermentation of
Topics: Alcohols; Antioxidants; Catechin; Chromatography, High Pressure Liquid; Fermentation; Fruit and Vegetable Juices; Hydrogen-Ion Concentration; Lactobacillales; Lactobacillus plantarum; Morinda; Pectins; Phenol; Plant Extracts; Plants, Medicinal; Sugars; Tea | 2019 |
Epigallocatechin-3-Gallate Suppresses Vasculogenic Mimicry through Inhibiting the Twist/VE-Cadherin/AKT Pathway in Human Prostate Cancer PC-3 Cells.
Topics: Antigens, CD; Cadherins; Catechin; Cell Line, Tumor; Cell Survival; Down-Regulation; Humans; Male; Neoplasm Invasiveness; Neovascularization, Pathologic; Nuclear Proteins; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction; Twist-Related Protein 1 | 2020 |
Solid-Phase Extraction of Catechins from Green Tea with Deep Eutectic Solvent Immobilized Magnetic Molybdenum Disulfide Molecularly Imprinted Polymer.
Topics: Catechin; Chromatography, High Pressure Liquid; Disulfides; Molecular Imprinting; Molybdenum; Polymers; Tea | 2020 |
Method development and validation for rapid identification of epigallocatechin gallate using ultra-high performance liquid chromatography.
Topics: Catechin; Chromatography, High Pressure Liquid; Limit of Detection | 2020 |
EGCG regulates CTR1 expression through its pro-oxidative property in non-small-cell lung cancer cells.
Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Cisplatin; Copper Transporter 1; Female; Humans; MAP Kinase Signaling System; Mice; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; RNA, Long Noncoding; Tea; Xenograft Model Antitumor Assays | 2020 |
Potential ameliorative effects of epigallocatechin-3-gallate against cigarette smoke exposure induced renal and hepatic deficits.
Topics: Animals; Catechin; Epithelial-Mesenchymal Transition; Fibrosis; Inflammation; Kidney; Liver; Liver Cirrhosis; Male; Oxidative Stress; Rats; Tobacco Smoke Pollution; Transforming Growth Factor beta1 | 2020 |
[Effect of epigallocatechin-3-gallate on liver lipid metabolism in rats with intrauterine growth restriction and related mechanism].
Topics: Animals; Catechin; Female; Fetal Growth Retardation; Insulin Resistance; Lipid Metabolism; Lipids; Liver; Pregnancy; Rats | 2020 |
Interaction of (-)-Epigallocatechin Gallate and Deoxyosones Blocking the Subsequent Maillard Reaction and Improving the Yield of
Topics: Alanine; Catechin; Glycation End Products, Advanced; Hot Temperature; Hydrogen-Ion Concentration; Maillard Reaction; Xylose; Xylulose | 2020 |
Controlled release and antioxidant activity of chitosan and β-lactoglobulin complex nanoparticles loaded with epigallocatechin gallate.
Topics: Antioxidants; Biphenyl Compounds; Caco-2 Cells; Catechin; Cell Survival; Chitosan; Humans; Lactoglobulins; Nanoparticles; Particle Size; Picrates; Surface Properties | 2020 |
Optimization of Ultrasound-Assisted Extraction Condition for Phenolic Compounds, Antioxidant Activity, and Epigallocatechin Gallate in Lipid-Extracted Microalgae.
Topics: Analysis of Variance; Antioxidants; Catechin; Chromatography, High Pressure Liquid; Ethanol; Lipids; Microalgae; Models, Chemical; Phenols; Reproducibility of Results; Temperature; Time Factors; Ultrasonics | 2020 |
Epigallocatechin Gallate Induces Upregulation of LDL Receptor via the 67 kDa Laminin Receptor-Independent Pathway in HepG2 Cells.
Topics: Antibodies; Catechin; Cholesterol; Gene Knockdown Techniques; Hep G2 Cells; Humans; Myosin Light Chains; Phosphorylation; Receptors, Laminin; Receptors, LDL; Ribosomal Proteins; Up-Regulation | 2020 |
Preparation and characterization of epigallocatechin gallate, ascorbic acid, gelatin, chitosan nanoparticles and their beneficial effect on wound healing of diabetic mice.
Topics: Animals; Ascorbic Acid; Catechin; Chitosan; Collagen; Diabetes Mellitus, Experimental; Gelatin; Male; Mice; Mice, Inbred ICR; Nanoparticles; Streptozocin; Wound Healing | 2020 |
Polycaprolactone vascular graft with epigallocatechin gallate embedded sandwiched layer-by-layer functionalization for enhanced antithrombogenicity and anti-inflammation.
Topics: Catechin; Coated Materials, Biocompatible; Heparin; Polyesters | 2020 |
Catechins reduce inflammation in lipopolysaccharide-stimulated dental pulp cells by inhibiting activation of the NF-κB pathway.
Topics: Catechin; Cells, Cultured; Dental Pulp; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; NF-kappa B; Signal Transduction; Tumor Necrosis Factor-alpha | 2020 |
Epigallocatechin-3-gallate protects Wharton's jelly derived mesenchymal stem cells against in vitro heat stress.
Topics: Burns; Catechin; Cells, Cultured; Hot Temperature; Humans; MAP Kinase Signaling System; Mesenchymal Stem Cells; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Wharton Jelly | 2020 |
Epigallocatechin gallate reduces uric acid levels by regulating xanthine oxidase activity and uric acid excretion in vitro and in vivo.
Topics: Animals; Antioxidants; Catechin; Liver; Monosaccharide Transport Proteins; Organic Anion Transporters, Sodium-Independent; Polyphenols; Rats; Rats, Sprague-Dawley; Tea; Uric Acid; Xanthine Oxidase | 2020 |
Interaction and action mechanism of starch with different phenolic compounds.
Topics: Catechin; Chlorogenic Acid; Gallic Acid; Humans; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning; Molecular Dynamics Simulation; Phenols; Spectroscopy, Fourier Transform Infrared; Starch; Tannins; Thermogravimetry | 2020 |
Quercetin potentiates antiradical properties of epigallocatechin-3-gallate in periodontium of rats under systemic and local administration of lipopolisaccharide of salmonella typhi
Topics: Animals; Antioxidants; Catechin; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Oxidative Stress; Periodontium; Quercetin; Rats; Rats, Wistar; Salmonella typhi | 2019 |
The green tea polyphenol epigallocatechin-3-gallate (EGCG) restores CDKL5-dependent synaptic defects in vitro and in vivo.
Topics: Animals; Brain; Catechin; Dyrk Kinases; Epileptic Syndromes; Hippocampus; Male; Mice; Mice, Knockout; Neurons; Phosphorylation; Polyphenols; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Spasms, Infantile; Tea | 2020 |
Antiviral Effect of Epigallocatechin Gallate via Impairing Porcine Circovirus Type 2 Attachment to Host Cell Receptor.
Topics: Animals; Antiviral Agents; Capsid; Catechin; Cell Line; Circovirus; Molecular Docking Simulation; Swine; Tea; Virus Attachment | 2020 |
Juá fruit (Ziziphus joazeiro) from Caatinga: A source of dietary fiber and bioaccessible flavanols.
Topics: Antioxidants; Biflavonoids; Brazil; Catechin; Chemical Phenomena; Dietary Fiber; Fruit; Nutritive Value; Phytochemicals; Plant Extracts; Polyphenols; Proanthocyanidins; Ziziphus | 2020 |
Induction of foxo3a protects turtle neurons against oxidative stress.
Topics: Animals; Catechin; Forkhead Box Protein O3; Hypoxia; Neurons; Neuroprotective Agents; Oxidative Stress; Oxygen; Turtles | 2020 |
(-)-Epigallocatechin gallate inhibits stemness and tumourigenicity stimulated by AXL receptor tyrosine kinase in human lung cancer cells.
Topics: Animals; Anticarcinogenic Agents; Axl Receptor Tyrosine Kinase; Carcinogenesis; Catechin; Cell Line, Tumor; Female; Humans; Lung Neoplasms; Mice, SCID; Neoplastic Stem Cells; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases | 2020 |
Coencapsulation and Stability Evaluation of Hydrophilic and Hydrophobic Bioactive Compounds in a Cagelike Phytoferritin.
Topics: Catechin; Drug Carriers; Drug Compounding; Drug Stability; Fabaceae; Ferritins; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Plant Proteins; Seeds | 2020 |
An online dual-enzyme co-immobilized microreactor based on capillary electrophoresis for enzyme kinetics assays and screening of dual-target inhibitors against thrombin and factor Xa.
Topics: Arginine; Catechin; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Electrophoresis, Capillary; Enzyme Activation; Enzyme Assays; Enzyme Inhibitors; Enzymes, Immobilized; Factor Xa; Kinetics; Molecular Docking Simulation; Pipecolic Acids; Rivaroxaban; Sulfonamides; Thrombin | 2020 |
Interactions between debranched starch and emulsifiers, polyphenols, and fatty acids.
Topics: Catechin; Emulsifying Agents; Fatty Acids; Polyphenols; Sodium Dodecyl Sulfate; Starch | 2020 |
(-)-Epigallocatechin-3-gallate provides neuroprotection via AMPK activation against traumatic brain injury in a mouse model.
Topics: AMP-Activated Protein Kinases; Animals; Behavior, Animal; Brain Injuries, Traumatic; Catechin; Cerebral Cortex; Cognition; Cytokines; Disease Models, Animal; Enzyme Activation; Inflammation Mediators; Male; Mice, Inbred C57BL; Mice, Knockout; Morris Water Maze Test; Motor Activity; Neuroprotective Agents; NF-kappa B; Oxidative Stress; Phosphorylation; Rotarod Performance Test; Signal Transduction | 2020 |
Efficacy of topical epigallocatechin gallate (EGCG) 1% on the healing of chronic plantar ulcers in leprosy.
Topics: Catechin; Foot Ulcer; Humans; Leprosy; Wound Healing | 2021 |
Epigallocatechin Gallate Mitigates the Methamphetamine-Induced Striatal Dopamine Terminal Toxicity by Preventing Oxidative Stress in the Mouse Brain.
Topics: Animals; Antioxidants; Catechin; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Male; Methamphetamine; Mice; Oxidative Stress | 2020 |
Biophysical Characterization of Epigallocatechin-3-Gallate Effect on the Cardiac Sodium Channel Na
Topics: Biophysical Phenomena; Catechin; Cell Line; Cell Membrane Permeability; Humans; Ion Channel Gating; Kinetics; Molecular Dynamics Simulation; Myocardium; NAV1.5 Voltage-Gated Sodium Channel; Sodium Channel Blockers | 2020 |
Molecular Rescue of Dyrk1A Overexpression Alterations in Mice with Fontup
Topics: Animals; Antioxidants; Biological Availability; Biomarkers; Blood-Brain Barrier; Brain; Catechin; Dietary Supplements; Down Syndrome; Dyrk Kinases; Liver; Mice; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Molecular Docking Simulation; Neuroprotective Agents; Polyphenols; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Tea; Up-Regulation | 2020 |
Epigallocatechin-3-gallate Inhibits Cu(II)-Induced β-2-Microglobulin Amyloid Formation by Binding to the Edge of Its β-Sheets.
Topics: Amyloid; Amyloidogenic Proteins; Amyloidosis; beta 2-Microglobulin; Catechin; Chromatography, Gel; Copper; Humans; Mass Spectrometry; Models, Molecular; Protein Conformation, beta-Strand; Protein Multimerization | 2020 |
Joint Toxicity of a Multi-Heavy Metal Mixture and Chemoprevention in Sprague Dawley Rats.
Topics: Animals; Bioaccumulation; Catechin; Chemoprevention; Glutathione; Male; Metals, Heavy; Rats; Rats, Sprague-Dawley; Sodium Citrate; Toxicity Tests | 2020 |
Dipeptidyl Peptidase-4 Is a Target Protein of Epigallocatechin-3-Gallate.
Topics: Catechin; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation | 2020 |
Impact of the Astaxanthin, Betanin, and EGCG Compounds on Small Oligomers of Amyloid Aβ
Topics: Amyloid beta-Peptides; Betacyanins; Catechin; Molecular Dynamics Simulation; Peptide Fragments; Protein Multimerization; Xanthophylls | 2020 |
Analysis of Cadmium, Epigallocatechin Gallate, and Vitamin C Co-exposure on PC12 Cellular Mechanisms.
Topics: Animals; Apoptosis; Ascorbic Acid; Cadmium; Catechin; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species | 2020 |
The effect of epigallocatechin-3-gallate on morphine-induced memory impairments in rat: EGCG effects on morphine neurotoxicity.
Topics: Animals; Apoptosis; Catechin; Glutathione Peroxidase; Hippocampus; Male; Malondialdehyde; Maze Learning; Memory; Memory Disorders; Morphine; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Rats, Wistar; Superoxide Dismutase | 2020 |
Conformational Insight on WT- and Mutated-EGFR Receptor Activation and Inhibition by Epigallocatechin-3-Gallate: Over a Rational Basis for the Design of Selective Non-Small-Cell Lung Anticancer Agents.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Cell Membrane; ErbB Receptors; Erlotinib Hydrochloride; Humans; Molecular Docking Simulation; Protein Binding; Protein Conformation; Protein Kinase Inhibitors; Protein Structure, Secondary | 2020 |
Self-responsive co-delivery system for remodeling tumor intracellular microenvironment to promote PTEN-mediated anti-tumor therapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Cytoplasm; Drug Delivery Systems; Gene Expression; Humans; Liposomes; Mice; Phosphatidylethanolamines; Plasmids; Polyethyleneimine; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Reactive Oxygen Species; Signal Transduction; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2020 |
Bio-transformation of green tea infusion with tannase and its improvement on adipocyte metabolism.
Topics: Adipocytes; Adiponectin; Animals; Aspergillus; Biocatalysis; Camellia sinensis; Carboxylic Ester Hydrolases; Catechin; Cell Differentiation; Food Handling; Fungal Proteins; Gallic Acid; Mice; NIH 3T3 Cells; Plant Extracts; Plant Leaves; Tea; Uncoupling Protein 1 | 2020 |
Effect of tea polyphenols on the oral and intravenous pharmacokinetics of ticagrelor in rats and its in vitro metabolism.
Topics: Adenosine; Administration, Intravenous; Administration, Oral; Animals; Catechin; Male; Microsomes, Liver; Platelet Aggregation Inhibitors; Polyphenols; Rats; Tea; Ticagrelor | 2020 |
EGCG ameliorates neuronal and behavioral defects by remodeling gut microbiota and TotM expression in Drosophila models of Parkinson's disease.
Topics: Animals; Behavior, Animal; Catechin; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Female; Gastrointestinal Microbiome; Heat-Shock Proteins; Male; Mitochondria; Neuroprotective Agents; Parkinson Disease | 2020 |
Reversal of TGFβ1-Driven Profibrotic State in Patients with Pulmonary Fibrosis.
Topics: Antioxidants; Biomarkers; Biopsy; Catechin; Collagen Type I; Humans; Pulmonary Fibrosis; Snail Family Transcription Factors; Transforming Growth Factor beta1 | 2020 |
Epigallocatechin-3-gallate Alleviates Cognitive Deficits in APP/PS1 Mice.
Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Catechin; Cognitive Dysfunction; Cytokines; Disease Models, Animal; Gene Expression Regulation; Humans; Mice; Mice, Transgenic; Mutation; Neuroprotective Agents; Presenilin-1; Treatment Outcome | 2020 |
Drug-based magnetic imprinted nanoparticles: Enhanced lysozyme amyloid fibrils cleansing and anti-amyloid fibrils toxicity.
Topics: Amyloid; Animals; Benzothiazoles; Catechin; Cell Line; Circular Dichroism; Magnetite Nanoparticles; Male; Mice; Muramidase | 2020 |
Inhibitory potential of EGCG on Streptococcus mutans biofilm: A new approach to prevent Cariogenesis.
Topics: Biofilms; Catechin; Dental Caries; Humans; Microscopy, Electron, Scanning; Molecular Docking Simulation; Streptococcus mutans; Tooth | 2020 |
Epigallocatechin-3-gallate enhances tomato resistance to tobacco mosaic virus by modulating RBOH1-dependent H
Topics: Catechin; Disease Resistance; Hydrogen Peroxide; Plant Proteins; Signal Transduction; Solanum lycopersicum; Tobacco Mosaic Virus | 2020 |
Preparation of a novel emulsifier by self-assembling of proanthocyanidins from Chinese bayberry (Myrica rubra Sieb. et Zucc.) leaves with gelatin.
Topics: Catechin; Emulsifying Agents; Emulsions; Fruit; Gelatin; Myrica; Plant Leaves; Proanthocyanidins | 2020 |
Cancer cell selective probe by mimicking EGCG.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Catechin; Cell Line, Tumor; Fluorescence; Gene Knockdown Techniques; Humans; Mice; Multiple Myeloma; Protein Binding; Proto-Oncogene Proteins c-akt; Receptors, Laminin; Signal Transduction | 2020 |
Effects of Propolis and Phenolic Acids on Triple-Negative Breast Cancer Cell Lines: Potential Involvement of Epigenetic Mechanisms.
Topics: Anticarcinogenic Agents; Catechin; Cell Line, Tumor; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Hydroxybenzoates; Molecular Docking Simulation; Propolis; Triple Negative Breast Neoplasms | 2020 |
(-)-Epigallocatechin-3-gallate (EGCG) attenuates salt-induced hypertension and renal injury in Dahl salt-sensitive rats.
Topics: Acute Kidney Injury; Administration, Oral; Animals; Apoptosis; Catechin; Cells, Cultured; Disease Models, Animal; Fibroblasts; Hypertension; Malondialdehyde; Phytotherapy; Rats; Rats, Inbred Dahl; Receptors, Laminin; Sodium Chloride, Dietary | 2020 |
The Aggregation Conditions Define Whether EGCG is an Inhibitor or Enhancer of
Topics: alpha-Synuclein; Amyloid; Catechin; Humans; Parkinson Disease; Protein Aggregates; Protein Aggregation, Pathological | 2020 |
Anticancer effects of epigallocatechin-3-gallate nanoemulsion on lung cancer cells through the activation of AMP-activated protein kinase signaling pathway.
Topics: AMP-Activated Protein Kinases; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Delivery Systems; Humans; Lung Neoplasms; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Signal Transduction | 2020 |
Interaction of Catechins with Human Erythrocytes.
Topics: Acetylcholinesterase; Antioxidants; Catechin; Erythrocytes; Hemolysis; Humans; Lipid Peroxidation; Manganese Compounds; Oxides | 2020 |
Green fabrication and characterization of debranched starch nanoparticles via ultrasonication combined with recrystallization.
Topics: Catechin; Crystallization; Free Radicals; Green Chemistry Technology; Hydrogen-Ion Concentration; Materials Testing; Nanoparticles; Nanotechnology; Particle Size; Sonication; Starch; Temperature | 2020 |
Epigallocatechin gallate alleviates neuronal cell damage against focal cerebral ischemia in rats.
Topics: Animals; Apoptosis; Brain Ischemia; Caspase 3; Catechin; Cerebral Infarction; Disease Models, Animal; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Poly(ADP-ribose) Polymerases; Rats, Sprague-Dawley | 2020 |
PTEN/AKT/mTOR signaling mediates anticancer effects of epigallocatechin‑3‑gallate in ovarian cancer.
Topics: A549 Cells; Animals; Antineoplastic Agents, Phytogenic; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Ovarian Neoplasms; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Signal Transduction; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2020 |
Anti‑glycolipid disorder effect of epigallocatechin‑3‑gallate on high‑fat diet and STZ‑induced T2DM in mice.
Topics: Animals; Blood Glucose; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Endothelial Cells; Glycolipids; Hypercholesterolemia; Hyperlipidemias; Insulin Resistance; Lipids; Lipoproteins, LDL; Male; Mice; Mice, Inbred C57BL; Sterol Regulatory Element Binding Protein 2; Streptozocin | 2020 |
Epigallocatechin Gallate Induces Hepatic Stellate Cell Senescence and Attenuates Development of Hepatocellular Carcinoma.
Topics: Animals; Anticarcinogenic Agents; Biomarkers; Carcinoma, Hepatocellular; Catechin; Cellular Senescence; Diethylnitrosamine; Hepatic Stellate Cells; Liver Cirrhosis; Liver Neoplasms, Experimental; Male; Phenotype; Precancerous Conditions; Rats; Tea; Transcriptome | 2020 |
Vitamin D plus epigallocatechin gallate: a novel promising approach for uterine myomas.
Topics: Administration, Oral; Adult; Catechin; Drug Therapy, Combination; Female; Humans; Leiomyoma; Middle Aged; Pilot Projects; Quality of Life; Severity of Illness Index; Treatment Outcome; Uterine Neoplasms; Vitamin D | 2020 |
A new epigallocatechin gallate derivative isolated from Anhua dark tea sensitizes the chemosensitivity of gefitinib via the suppression of PI3K/mTOR and epithelial-mesenchymal transition.
Topics: Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; China; Drug Synergism; Epithelial-Mesenchymal Transition; Gefitinib; Humans; Molecular Structure; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phytochemicals; Tea; TOR Serine-Threonine Kinases | 2020 |
Beneficial effects of (-)-epigallocatechin-3-O-gallate on diabetic peripheral neuropathy in the rat model.
Topics: Animals; Catechin; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Male; Peripheral Nervous System Diseases; Rats | 2020 |
Epigallocatechin Gallate Suppresses Inflammatory Responses by Inhibiting Toll-like Receptor 4 Signaling and Alleviates Insulin Resistance in the Livers of High-fat-diet Rats.
Topics: Animals; Anti-Inflammatory Agents; Catechin; Diet, High-Fat; Inflammation; Insulin Resistance; Liver; Liver Diseases; Phytotherapy; Rats, Sprague-Dawley; Signal Transduction; Tea; Toll-Like Receptor 4 | 2020 |
Difference in the antibacterial action of epigallocatechin gallate and theaflavin 3,3'-di-O-gallate on Bacillus coagulans.
Topics: Anti-Bacterial Agents; Bacillus coagulans; Biflavonoids; Catechin; Cell Membrane; Glucose; Membrane Transport Proteins; Microbial Viability; Polyphenols; Tea | 2020 |
Efficacy of Topical Treatment with (-)-Epigallocatechin Gallate, A Green Tea Catechin, in Mice with Cutaneous Leishmaniasis.
Topics: Animals; Antiprotozoal Agents; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Leishmania mexicana; Leishmaniasis, Cutaneous; Mice; Parasitic Sensitivity Tests; Tea | 2020 |
Interaction of quercetin and epigallocatechin gallate (EGCG) aggregates with pancreatic lipase under simplified intestinal conditions.
Topics: Animals; Antioxidants; Catechin; Dimerization; Enzyme Inhibitors; Intestinal Mucosa; Lipase; Quercetin; Swine | 2020 |
Protective effect of epigallocatechin-3-gallate against neuroinflammation and anxiety-like behavior in a rat model of myocardial infarction.
Topics: Animals; Anxiety; Apoptosis; Catechin; Hippocampus; Myocardial Infarction; Rats | 2020 |
Green Tea Catechin (-)-Epigallocatechin-3-Gallate (EGCG) Facilitates Fracture Healing.
Topics: Animals; Biomechanical Phenomena; Bony Callus; Catechin; Fracture Healing; Male; Rats, Sprague-Dawley; Tea; Tibia; Tibial Fractures; X-Ray Microtomography | 2020 |
Effect of (-)-Epigallocatechin Gallate to Staphylococcal Enterotoxin A on Toxin Activity.
Topics: Animals; Catechin; Cell Proliferation; Cytokines; Drug Interactions; Enterotoxins; Female; Gene Expression Regulation; Hydrogen-Ion Concentration; Mice; Molecular Structure; Pancreatin; Pepsin A; Protein Binding | 2020 |
Comparative Kinetics of Acetyl- and Butyryl-Cholinesterase Inhibition by Green Tea Catechins|Relevance to the Symptomatic Treatment of Alzheimer's Disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Anti-Inflammatory Agents; Antioxidants; Butyrylcholinesterase; Catechin; Cholinergic Neurons; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Eels; Horses; Humans; Phytotherapy; Tea | 2020 |
A new analytical concept based on chemistry and toxicology for herbal extracts analysis: From phenolic composition to bioactivity.
Topics: A549 Cells; alpha-Amylases; Angiotensins; Animals; Antioxidants; Aspalathus; Camellia sinensis; Catechin; Cell Line; Cholesterol, LDL; DNA Cleavage; Hesperidin; Humans; Hypertension; Ilex paraguariensis; Male; Oxygen Radical Absorbance Capacity; Phenols; Phytochemicals; Plant Extracts; Plant Leaves; Quercetin; Rats; Rats, Wistar; Rutin | 2020 |
Epigallocatechin gallate enhances the motor neuron survival and functional recovery after brachial plexus root avulsion by regulating FIG4.
Topics: Animals; Brachial Plexus; Catechin; Cell Death; Cell Survival; Flavoproteins; Mice, Inbred C57BL; Motor Neurons; Neuroprotective Agents; Oxidative Stress; Phosphoinositide Phosphatases; Recovery of Function; Spinal Cord | 2019 |
Inhibitory effect of a weight-loss Chinese herbal formula RCM-107 on pancreatic α-amylase activity: Enzymatic and in silico approaches.
Topics: Animals; Anti-Obesity Agents; Carbohydrate Metabolism; Catechin; Cholestenones; Drugs, Chinese Herbal; Enzyme Assays; Flavanones; Glucosides; Humans; Molecular Docking Simulation; Obesity; Pancreatic alpha-Amylases; Swine; Weight Loss | 2020 |
An intelligent nanodevice based on the synergistic effect of telomerase-triggered photodynamic therapy and gene-silencing for precise cancer cell therapy.
Topics: Catechin; Cell Line, Tumor; Cell Survival; Chlorophyllides; DNA; DNA, Catalytic; Gene Silencing; Humans; Light; Manganese Compounds; Nanostructures; Neoplasms; Oxides; Photochemotherapy; Photosensitizing Agents; Porphyrins; RNA, Messenger; Survivin; Telomerase | 2020 |
Surface engineering of titanium alloy using metal-polyphenol network coating with magnesium ions for improved osseointegration.
Topics: Adipose Tissue; Alloys; Animals; Catechin; Cell Differentiation; Cell Proliferation; Humans; Magnesium; Male; Mice; Osseointegration; Osteogenesis; Polyphenols; Rabbits; RAW 264.7 Cells; Stem Cells; Surface Properties; Tibia; Titanium | 2020 |
Prefrontal-hippocampal functional connectivity encodes recognition memory and is impaired in intellectual disability.
Topics: Animals; Catechin; Disease Models, Animal; Down Syndrome; Executive Function; Female; Hippocampus; Male; Mice; Mice, Inbred C57BL; Nerve Net; Neuroprotective Agents; Prefrontal Cortex; Recognition, Psychology | 2020 |
Epigallocatechin Gallate Enhances MAL-PDT Cytotoxic Effect on PDT-Resistant Skin Cancer Squamous Cells.
Topics: Aminolevulinic Acid; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Catechin; Cell Death; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Combined Modality Therapy; Ferrochelatase; Heat-Shock Proteins; Humans; Membrane Transport Proteins; Molecular Chaperones; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Reactive Oxygen Species; Skin Neoplasms; Stress, Physiological; Superoxide Dismutase; Survivin; Symporters | 2020 |
Effect of Green Tea and (-)-Epigallocatechin Gallate on the Pharmacokinetics of Rosuvastatin.
Topics: Administration, Oral; Animals; Caco-2 Cells; Camellia sinensis; Catechin; Food-Drug Interactions; HEK293 Cells; Humans; Liver-Specific Organic Anion Transporter 1; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Rosuvastatin Calcium; Tea | 2020 |
A prodrug of epigallocatechin-3-gallate alleviates high glucose-induced pro-angiogenic factor production by inhibiting the ROS/TXNIP/NLRP3 inflammasome axis in retinal Müller cells.
Topics: Angiogenesis Inducing Agents; Animals; Blotting, Western; Carrier Proteins; Catechin; Cell Count; Cell Proliferation; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Ependymoglial Cells; Glucose; Inflammasomes; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Prodrugs; Reactive Oxygen Species; Sincalide; Superoxide Dismutase; Thioredoxins; Transfection | 2020 |
Broccoli byproducts for protection and co-delivery of EGCG and tuna oil.
Topics: Animals; Biological Availability; Brassica; Catechin; Dietary Supplements; Digestion; Emulsions; Fish Oils; Food; Oxidation-Reduction; Powders; Refuse Disposal; Tuna; Waste Products | 2020 |
Improved viability of Akkermansia muciniphila by encapsulation in spray dried succinate-grafted alginate doped with epigallocatechin-3-gallate.
Topics: Akkermansia; Alginates; Antioxidants; Capsules; Catechin; Coated Materials, Biocompatible; Magnetic Resonance Spectroscopy; Microbial Viability; Microgels; Molecular Structure; Oxidation-Reduction; Particle Size; Phosphatidylethanolamines; Spectroscopy, Fourier Transform Infrared; Succinic Acid; Surface Properties | 2020 |
Analysis of β-lactoglobulin-epigallocatechin gallate interactions: the antioxidant capacity and effects of polyphenols under different heating conditions in polyphenolic-protein interactions.
Topics: Animals; Antioxidants; Catechin; Cattle; Food Handling; Hot Temperature; Lactoglobulins; Polyphenols; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2020 |
Effect of epigallocatechin-3-gallate (EGCG) on embryos inseminated with oxidative stress-induced DNA damage sperm.
Topics: Animals; Antioxidants; Ataxia Telangiectasia Mutated Proteins; Catechin; Cryopreservation; DNA Damage; Embryonic Development; Female; Fertilization in Vitro; Hydrogen Peroxide; Male; Mice; Oxidative Stress; Pregnancy; Semen Preservation; Spermatozoa | 2020 |
Epigallocatechin-3-gallate (EGCG) Alters Histone Acetylation and Methylation and Impacts Chromatin Architecture Profile in Human Endothelial Cells.
Topics: Acetylation; Activating Transcription Factor 2; Catechin; Cell Line; Chromatin; Chromobox Protein Homolog 5; Chromosomal Proteins, Non-Histone; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Human Umbilical Vein Endothelial Cells; Humans; Methylation; Myeloid-Lymphoid Leukemia Protein; p300-CBP Transcription Factors; Protein Processing, Post-Translational; Tea | 2020 |
Theaphenon E prevents fatty liver disease and increases CD4+ T cell survival in mice fed a high-fat diet.
Topics: Animals; Apoptosis; Catechin; CD4-Positive T-Lymphocytes; Cell Proliferation; Diet, Fat-Restricted; Diet, High-Fat; Disease Models, Animal; Fatty Acids; Hepatocytes; Humans; Linoleic Acid; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity | 2021 |
Anti-melanogenic effects of epigallocatechin-3-gallate (EGCG), epicatechin-3-gallate (ECG) and gallocatechin-3-gallate (GCG) via down-regulation of cAMP/CREB /MITF signaling pathway in B16F10 melanoma cells.
Topics: Animals; Catechin; Cell Line, Tumor; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Down-Regulation; Melanins; Melanoma, Experimental; Mice; Microphthalmia-Associated Transcription Factor; Molecular Structure; Monophenol Monooxygenase; Signal Transduction; Tea | 2020 |
Structural dynamic studies on identification of EGCG analogues for the inhibition of Human Papillomavirus E7.
Topics: Antiviral Agents; Catechin; Cell Proliferation; Chemoprevention; Drug Discovery; Drug Evaluation, Preclinical; Female; High-Throughput Screening Assays; Human papillomavirus 16; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Papillomavirus E7 Proteins; Papillomavirus Infections; Principal Component Analysis; Protein Conformation; Uterine Cervical Neoplasms; Virus Internalization | 2020 |
Folate decorated epigallocatechin-3-gallate (EGCG) loaded PLGA nanoparticles; in-vitro and in-vivo targeting efficacy against MDA-MB-231 tumor xenograft.
Topics: Animals; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Carriers; Drug Liberation; Drug Stability; Female; Folic Acid; Half-Life; Humans; Male; MCF-7 Cells; Mice; Mice, Nude; Nanoparticles; Particle Size; Rats; Rats, Sprague-Dawley; Surface Properties; Technetium | 2020 |
Whey protein and phenolic compound complexation: Effects on antioxidant capacity before and after in vitro digestion.
Topics: Antioxidants; Caffeic Acids; Catechin; Digestion; Gastrointestinal Tract; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Phenols; Whey Proteins | 2020 |
Intra-Pancreatic Insulin Nourishes Cancer Cells: Do Insulin-Receptor Antagonists such as PGG and EGCG Play a Role?
Topics: Animals; Catechin; Cell Line, Tumor; Gene Expression; Humans; Hydrolyzable Tannins; Insulin; Insulin-Like Growth Factor I; Male; Mice, Nude; Pancreatic Neoplasms; Receptor, Insulin; Streptozocin | 2020 |
The inhibitory effect of the catechin structure on advanced glycation end product formation in alcoholic media.
Topics: alpha-Amylases; alpha-Glucosidases; Antioxidants; Binding Sites; Biphenyl Compounds; Catechin; Glucosidases; Glycation End Products, Advanced; Glycosylation; Molecular Docking Simulation; Picrates; Pyruvaldehyde | 2020 |
EGCG down-regulates MuRF1 expression through 67-kDa laminin receptor and the receptor signaling is amplified by eriodictyol.
Topics: Animals; Catechin; Down-Regulation; Flavanones; Mice; Muscle Proteins; Plants; Receptors, Laminin; Signal Transduction; Tripartite Motif Proteins; Ubiquitin-Protein Ligases | 2020 |
Epigallocatechin-3-gallate sensitises multidrug-resistant oral carcinoma xenografts to vincristine sulfate.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Catechin; Cell Proliferation; Chick Embryo; Chickens; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Injections, Intraperitoneal; KB Cells; Mice; Mice, Nude; Mouth Neoplasms; Neoplasms, Experimental; RNA, Messenger; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vincristine | 2020 |
Anti-inflammatory and antixidant properties of blend formulated with compounds of Malpighia emarginata D.C (acerola) and Camellia sinensis L. (green tea) in lipopolysaccharide-stimulated RAW 264.7 macrophages.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Camellia sinensis; Catechin; Cytokines; Inflammation; Inflammation Mediators; Lipopolysaccharides; Macrophages; Malpighiaceae; Mice; Plant Extracts; RAW 264.7 Cells | 2020 |
Amyloid Aggregation of Insulin: An Interaction Study of Green Tea Constituents.
Topics: Amyloid; Binding Sites; Caffeine; Catechin; Gallic Acid; Humans; Insulin; Kinetics; Molecular Docking Simulation; Protein Aggregates; Protein Structure, Secondary; Tea | 2020 |
The impact of blue light in monolayers representing tumorigenic and nontumorigenic cell membranes containing epigallocatechin-3-gallate.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Catechin; Cell Membrane; Light; Particle Size; Phosphatidylserines; Surface Properties | 2020 |
Integrated transcriptomic and metabolomic analyses to characterize the anti-cancer effects of (-)-epigallocatechin-3-gallate in human colon cancer cells.
Topics: Anticarcinogenic Agents; Catechin; Cell Proliferation; Colonic Neoplasms; HT29 Cells; Humans; Metabolomics; Transcriptome | 2020 |
Epigallocatechin gallate reverses gastric cancer by regulating the long noncoding RNA LINC00511/miR-29b/KDM2A axis.
Topics: Apoptosis; Carcinogenesis; Catechin; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; F-Box Proteins; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Jumonji Domain-Containing Histone Demethylases; MicroRNAs; RNA-Seq; RNA, Long Noncoding; Stomach Neoplasms | 2020 |
Epigallocatechin-3-gallate (EGCG) protects the oocytes from methyl parathion-induced cytoplasmic deformities by suppressing oxidative and endoplasmic reticulum stress.
Topics: Animals; Catechin; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Methyl Parathion; Mice; Oocytes; Oxidative Stress | 2020 |
Preparation of debranched starch nanoparticles by ionic gelation for encapsulation of epigallocatechin gallate.
Topics: Caco-2 Cells; Catechin; Cations; Cell Line, Tumor; Delayed-Action Preparations; Gels; Humans; Nanoparticles; Particle Size; Starch | 2020 |
Epigallocatechin gallate inhibits dimethylhydrazine-induced colorectal cancer in rats.
Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Carcinogenesis; Catechin; Cell Proliferation; Colon; Colorectal Neoplasms; Dimethylhydrazines; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Intestinal Mucosa; Male; Neoplasms, Experimental; Protein Interaction Maps; Rats; Rectum; Signal Transduction | 2020 |
Augmentation of Bone Regeneration by Depletion of Stress-Induced Senescent Cells Using Catechin and Senolytics.
Topics: Aldehydes; Animals; Bone Regeneration; Bone Substitutes; Catechin; Cell Line; Cellular Senescence; Dasatinib; Delayed-Action Preparations; Lipopolysaccharides; Osteoblasts; Quercetin; Rats; Skull; X-Ray Microtomography | 2020 |
Baiyacha, a wild tea plant naturally occurring high contents of theacrine and 3″-methyl-epigallocatechin gallate from Fujian, China.
Topics: Alkaloids; Caffeine; Camellia; Catechin; China; Gallic Acid; Plant Extracts; Plant Leaves; Tea; Teas, Herbal; Uric Acid | 2020 |
Epigallocatechin-3-Gallate Protects H
Topics: Apoptosis; Catechin; Cell Movement; Cell Survival; Dose-Response Relationship, Drug; Female; Humans; Hydrogen Peroxide; Inflammation; Male; Membrane Proteins; Middle Aged; NLR Family, Pyrin Domain-Containing 3 Protein; Nucleotidyltransferases; Nucleus Pulposus; Structure-Activity Relationship | 2020 |
Natural compounds attenuate heavy metal-induced PC12 cell damage.
Topics: alpha-Tocopherol; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Caffeine; Catechin; Cell Survival; China; Gallic Acid; Heavy Metal Poisoning; Metals, Heavy; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Resveratrol | 2020 |
Modulation of gastrointestinal digestion of β-lactoglobulin and micellar casein following binding by (-)-epigallocatechin-3-gallate (EGCG) and green tea flavanols.
Topics: Antioxidants; Camellia sinensis; Caseins; Catechin; Diet; Dietary Proteins; Digestion; Flavonoids; Food-Drug Interactions; Humans; Lactoglobulins; Micelles; Pancreatin; Pepsin A; Plant Extracts; Polyphenols; Protein Binding; Tea | 2020 |
Enhancement of the permeability and activities of epigallocatechin gallate by quaternary ammonium chitosan/fucoidan nanoparticles.
Topics: alpha-Amylases; alpha-Glucosidases; Catechin; Chitosan; Enzyme Inhibitors; Fucus; Nanoparticles; Particle Size; Polysaccharides; Quaternary Ammonium Compounds; Surface Properties | 2020 |
Epigallocatechin-3-gallate protects immunity and liver drug-metabolism function in mice loaded with restraint stress.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Biotransformation; Catechin; Cytochrome P-450 Enzyme System; Cytokines; Disease Models, Animal; Female; Immunoglobulin A, Secretory; Immunologic Factors; Inflammation Mediators; Isoenzymes; Liver; Male; Mice, Inbred ICR; Oxidative Stress; Restraint, Physical; Stress, Physiological; Stress, Psychological; T-Lymphocyte Subsets | 2020 |
Epigallocatechin-3-gallate activates the AMP-activated protein kinase signaling pathway to reduce lipid accumulation in canine hepatocytes.
Topics: AMP-Activated Protein Kinases; Animals; Catechin; Cells, Cultured; Diet, High-Fat; Dogs; Down-Regulation; Hepatocytes; Lipid Metabolism; Liver; PPAR alpha; Pyrazoles; Pyrimidines; Signal Transduction; Sterol Regulatory Element Binding Protein 1; Transcription, Genetic; Triglycerides; Up-Regulation | 2021 |
Epigallocatechin-3-Gallate (EGCG), an Active Compound of Green Tea Attenuates Acute Lung Injury Regulating Macrophage Polarization and Krüpple-Like-Factor 4 (KLF4) Expression.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Lung Injury; Animals; Anti-Inflammatory Agents; Arginase; beta-N-Acetylhexosaminidases; Catechin; Cell Proliferation; Interleukin-1beta; Interleukin-6; Ki-67 Antigen; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lectins; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Peroxidase; Proliferating Cell Nuclear Antigen; Tea; Triggering Receptor Expressed on Myeloid Cells-1; Tumor Necrosis Factor-alpha; Tyrosine | 2020 |
Challenges in confectionery industry: Development and storage stability of innovative white tea-based candies.
Topics: Antioxidants; Camellia sinensis; Candy; Catechin; Food Additives; Food Handling; Food Storage; Gelatin; Plant Extracts | 2020 |
The Effect of (-)-Epigallocatechin-3-Gallate on the Amyloid-β Secondary Structure.
Topics: Amyloid; Amyloid beta-Peptides; Catechin; Peptide Fragments; Protein Structure, Secondary | 2020 |
Evaluation of the therapeutic potential of Epigallocatechin-3-gallate (EGCG) via oral gavage in young adult Down syndrome mice.
Topics: Administration, Oral; Animals; Body Weight; Cancellous Bone; Catechin; Disease Models, Animal; Down Syndrome; Femur; Maze Learning; Mice; Treatment Outcome; X-Ray Microtomography | 2020 |
Covalent conjugation with (-)-epigallo-catechin 3-gallate and chlorogenic acid changes allergenicity and functional properties of Ara h1 from peanut.
Topics: Antigens, Plant; Antioxidants; Arachis; Basophils; Catechin; Chlorogenic Acid; Epitopes; Histamine; Humans; Immunoglobulin E; Membrane Proteins; Peanut Hypersensitivity; Plant Proteins; Protein Conformation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectroscopy, Fourier Transform Infrared | 2020 |
Principal component analysis of data from NMR titration experiment of uniformly
Topics: Amyloid; Amyloid beta-Peptides; Catechin; Cinnamates; Curcumin; Depsides; Escherichia coli; Humans; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Phenols; Principal Component Analysis; Protein Conformation; Rosmarinic Acid; Temperature; Thermodynamics | 2020 |
Green Tea Encourages Growth of
Topics: Akkermansia; Animals; Catechin; Diet, High-Fat; Gastrointestinal Microbiome; Male; Mice; Mice, Inbred BALB C; Tea | 2020 |
Long-acting mucoadhesive thermogels for improving topical treatments of dry eye disease.
Topics: Acrylic Resins; Administration, Topical; Animals; Apoptosis; Catechin; Cell Line; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Dry Eye Syndromes; Female; Gelatin; Humans; Lectins; Ophthalmic Solutions; Oxidative Stress; Rabbits | 2020 |
Injectable anti-inflammatory hyaluronic acid hydrogel for osteoarthritic cartilage repair.
Topics: Animals; Anti-Inflammatory Agents; Cartilage, Articular; Catechin; Cells, Cultured; Drug Synergism; Gelatin; Hyaluronic Acid; Hydrogels; Injections; Interleukin-1beta; Male; Mice; Osteoarthritis; Regeneration; Swine; Tyramine | 2020 |
Epigallocatechin-3-gallate (EGCG) inhibits myofibroblast transformation of human Tenon's fibroblasts.
Topics: Catechin; Cell Movement; Cell Proliferation; Cells, Cultured; Fibroblasts; Glaucoma; Humans; Myofibroblasts; Neuroprotective Agents; Protease Inhibitors; Signal Transduction; Tenon Capsule | 2020 |
Enhanced Chemotherapeutic Efficacy of PLGA-Encapsulated Epigallocatechin Gallate (EGCG) Against Human Lung Cancer.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Survival; Drug Liberation; Endocytosis; Humans; Lung Neoplasms; Nanoparticles; NF-kappa B; Polylactic Acid-Polyglycolic Acid Copolymer | 2020 |
Feature-Based Molecular Networking Analysis of the Metabolites Produced by
Topics: Bacteria; Camellia sinensis; Catechin; Fermentation; Flavonoids; Flavonols; Food Handling; Food Microbiology; Tea | 2020 |
Synthesis, antitumor activity, and molecular docking of (-)-epigallocatechin-3-gallate-4β-triazolopodophyllotoxin conjugates.
Topics: Antineoplastic Agents; Catechin; Molecular Docking Simulation; Molecular Structure | 2021 |
The epigallocatechin gallate derivative Y6 reduces the cardiotoxicity and enhances the efficacy of daunorubicin against human hepatocellular carcinoma by inhibiting carbonyl reductase 1 expression.
Topics: Alcohol Oxidoreductases; Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arrhythmias, Cardiac; Carcinoma, Hepatocellular; Cardiotoxicity; Catechin; Cell Proliferation; Daunorubicin; Drug Synergism; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Heart Rate; Hep G2 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays | 2020 |
Preparation of Strong Antioxidative, Therapeutic Nanoparticles Based on Amino Acid-Induced Ultrafast Assembly of Tea Polyphenols.
Topics: Amino Acids; Animals; Antioxidants; Catechin; Cell Line, Tumor; Cell Survival; Female; Indoles; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Particle Size; Polymers; Polyphenols; Tea; Tissue Distribution; Transplantation, Homologous | 2020 |
Aldose Reductase Differential Inhibitors in Green Tea.
Topics: Aldehyde Reductase; Catalytic Domain; Catechin; Enzyme Inhibitors; Gallic Acid; Glutathione; Hexoses; Humans; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; Plant Extracts; Tea | 2020 |
Protective Role of EGCG Against Malathion Induced Genotoxicity Using Human Lymphocytes.
Topics: Adult; Antioxidants; Camellia sinensis; Catechin; DNA Damage; Female; Flavonoids; Humans; Lipid Peroxidation; Lymphocytes; Malathion; Male; Oxidative Stress; Plant Extracts; Protective Agents; Tea; Young Adult | 2020 |
Brain-targeted co-delivery of β-amyloid converting enzyme 1 shRNA and epigallocatechin-3-gallate by multifunctional nanocarriers for Alzheimer's disease treatment.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Blood-Brain Barrier; Brain; Catechin; Disease Models, Animal; Humans; Mice; Mice, Transgenic; RNA, Small Interfering | 2020 |
Soy protein isolate -(-)-epigallocatechin gallate conjugate: Covalent binding sites identification and IgE binding ability evaluation.
Topics: Amino Acids; Binding Sites; Catechin; Immunoglobulin E; Polyphenols; Protein Binding; Soybean Proteins | 2020 |
Activation of Myosin Phosphatase by Epigallocatechin-Gallate Sensitizes THP-1 Leukemic Cells to Daunorubicin.
Topics: Antineoplastic Agents; Catechin; Cell Proliferation; Cell Survival; Daunorubicin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Myosin-Light-Chain Phosphatase; Structure-Activity Relationship; THP-1 Cells; Tumor Cells, Cultured | 2021 |
Effect of epigallocatechin gallate on gene expression of Staphylococcus aureus.
Topics: Catechin; Gene Expression; Staphylococcus aureus; Tea | 2020 |
Epigallocatechin gallate but not catechin prevents nonalcoholic steatohepatitis in mice similar to green tea extract while differentially affecting the gut microbiota.
Topics: Animals; Catechin; Gastrointestinal Microbiome; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Protective Agents; Tea | 2020 |
Evidence that polyphenols do not inhibit the phospholipid scramblase TMEM16F.
Topics: Animals; Anoctamins; Catechin; Enzyme Inhibitors; HEK293 Cells; Humans; Mice; Phospholipid Transfer Proteins; Phospholipids; Polyphenols; Tannins | 2020 |
The green tea polyphenol epigallocatechin-3-gallate attenuates age-associated muscle loss via regulation of miR-486-5p and myostatin.
Topics: Aging; Animals; Catechin; Cell Line; Gene Expression Regulation; Mice; Mice, Transgenic; MicroRNAs; Muscle Proteins; Muscular Atrophy; Myostatin; Tea | 2020 |
Modulation of non-steroidal anti-inflammatory drug-induced, ER stress-mediated apoptosis in Caco-2 cells by different polyphenolic antioxidants: a mechanistic study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Caco-2 Cells; Catechin; Diclofenac; Endoplasmic Reticulum Stress; Humans; Indomethacin; Intestinal Mucosa; Lignans; Mitochondria; Oxidative Stress; Signal Transduction; Thapsigargin; Tunicamycin; Unfolded Protein Response | 2020 |
EGCG impedes human Tau aggregation and interacts with Tau.
Topics: Catechin; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; tau Proteins; Thermodynamics | 2020 |
Epigallocatechin gallate suppresses inflammation in human coronary artery endothelial cells by inhibiting NF-κB.
Topics: Catechin; Cell Adhesion; Cell Membrane Permeability; Coronary Vessels; Endothelial Cells; Humans; Inflammation; Inflammation Mediators; Monocytes; NF-kappa B; Tumor Necrosis Factor-alpha | 2020 |
Does deamidation affect inhibitory mechanisms towards amyloid protein aggregation?
Topics: Amino Acid Sequence; Amyloid; Catechin; Humans; Islet Amyloid Polypeptide; Microscopy, Electron, Transmission; Protein Aggregates; Spectrometry, Fluorescence | 2020 |
Insights into the Effect of Curcumin and (-)-Epigallocatechin-3-Gallate on the Aggregation of Aβ(1-40) Monomers by Means of Molecular Dynamics.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Brain; Catechin; Curcumin; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Peptide Fragments; Plaque, Amyloid; Protein Aggregates | 2020 |
Polyphenol-Conjugated Bimetallic Au@AgNPs for Improved Wound Healing.
Topics: Animals; Antioxidants; Biflavonoids; Catechin; Gold; Metal Nanoparticles; Mice; Polyphenols; Proanthocyanidins; Silver; Tannins; Wound Healing | 2020 |
Role of Nrf2 dysfunction in the pathogenesis of diabetic nephropathy: Therapeutic prospect of epigallocatechin-3-gallate.
Topics: Animals; Catechin; Diabetes Mellitus; Diabetic Nephropathies; Humans; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Oxidative Stress | 2020 |
Blockade of RANKL/RANK signaling pathway by epigallocatechin gallate alleviates mast cell-mediated inflammatory reactions.
Topics: Caspase 1; Catechin; Cell Line; Cell Survival; Cytokines; Elafin; Histamine; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Interleukin-8; Mast Cells; Mitogen-Activated Protein Kinases; NF-kappa B; RANK Ligand; Signal Transduction; Thymic Stromal Lymphopoietin | 2020 |
Epigallocatechin gallate and theaflavin gallate interaction in SARS-CoV-2 spike-protein central channel with reference to the hydroxychloroquine interaction: Bioinformatics and molecular docking study.
Topics: Angiotensin-Converting Enzyme 2; Biflavonoids; Binding Sites; Catechin; Computational Biology; COVID-19; Gallic Acid; Humans; Hydroxychloroquine; Molecular Docking Simulation; Protein Structure, Secondary; Protein Structure, Tertiary; Spike Glycoprotein, Coronavirus; X-Ray Diffraction | 2021 |
Epigallocatechin-3-gallate mobilizes intracellular Ca
Topics: Antioxidants; Calcium; Catechin; Cell Survival; Dose-Response Relationship, Drug; Humans; Intracellular Fluid; Male; PC-3 Cells; Prostatic Neoplasms | 2020 |
Epigallocatechin-3-gallate preconditioned Adipose-derived Stem Cells confer Neuroprotection in aging rat brain.
Topics: Adipocytes; Aging; Animals; Catechin; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Humans; Mesenchymal Stem Cells; Neurogenesis; Neuroprotective Agents; Rats; Signal Transduction; Taiwan | 2020 |
Epigallocatechin gallate diminishes cigarette smoke-induced oxidative stress, lipid peroxidation, and inflammation in human bronchial epithelial cells.
Topics: Aldehydes; Alveolar Epithelial Cells; Anti-Inflammatory Agents; Antioxidants; Bronchi; Catechin; Cell Line; Cigarette Smoking; Epithelial Cells; Humans; Inflammation; Lipid Peroxidation; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Pulmonary Alveoli; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Signal Transduction; Smoke; Smoking | 2020 |
Dual effects of ascorbic acid on the stability of EGCG by the oxidation product dehydroascorbic acid promoting the oxidation and inhibiting the hydrolysis pathway.
Topics: Ascorbic Acid; Catechin; Dehydroascorbic Acid; Hydrolysis; Oxidation-Reduction; Tea; Temperature | 2021 |
General Nanomedicine Platform by Solvent-Mediated Disassembly/Reassembly of Scalable Natural Polyphenol Colloidal Spheres.
Topics: Animals; Catechin; Cell Survival; Doxorubicin; Drug Carriers; Female; Humans; Hydrophobic and Hydrophilic Interactions; MCF-7 Cells; Mice; Mice, Inbred BALB C; Nanomedicine; Nanoparticles; Neoplasms; Polyphenols; Solvents; Transplantation, Heterologous | 2020 |
Reciprocal Interactions between Epigallocatechin-3-gallate (EGCG) and Human Gut Microbiota
Topics: Adult; Bacteria; Catechin; Female; Fermentation; Gastrointestinal Microbiome; Humans; Male; Mass Spectrometry; Propionates; Young Adult | 2020 |
EGCG sensitizes chemotherapeutic-induced cytotoxicity by targeting the ERK pathway in multiple cancer cell lines.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Catechin; Cytotoxins; HT29 Cells; Humans; MAP Kinase Signaling System; Neoplasms | 2020 |
Predicting the effect of tea polyphenols on ticagrelor by incorporating transporter-enzyme interplay mechanism.
Topics: Adenosine; Biological Transport; Caco-2 Cells; Catechin; Cell Line, Tumor; Drug Interactions; Humans; Intestinal Absorption; Kinetics; Microsomes, Liver; Models, Theoretical; Platelet Aggregation Inhibitors; Polyphenols; Purinergic P2Y Receptor Antagonists; Tea; Ticagrelor | 2020 |
Interactions in starch co-gelatinized with phenolic compound systems: Effect of complexity of phenolic compounds and amylose content of starch.
Topics: Amylose; Caffeic Acids; Catechin; Phenols; Quercetin; Starch; Temperature; Viscosity; Zea mays | 2020 |
Effect of epigallocatechin-3-gallate on the status of DNA methylation of E-cadherin promoter region on endometriosis mouse.
Topics: Animals; Cadherins; Catechin; DNA Methylation; Endometriosis; Female; Humans; Mice; Mice, Nude; Promoter Regions, Genetic | 2020 |
The Development of Hyaluronan/Fucoidan-Based Nanoparticles as Macrophages Targeting an Epigallocatechin-3-Gallate Delivery System.
Topics: Animals; Catechin; Cell Movement; Drug Carriers; Drug Delivery Systems; Hyaluronan Receptors; Hyaluronic Acid; Inflammation; Lipopolysaccharides; Macrophages; Mice; Nanoparticles; Polysaccharides; RAW 264.7 Cells | 2020 |
The gelation properties of myofibrillar proteins prepared with malondialdehyde and (-)-epigallocatechin-3-gallate.
Topics: Animals; Catechin; Elastic Modulus; Gels; Malondialdehyde; Meat Proteins; Muscle, Skeletal; Myofibrils; Rheology; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Swine; Water | 2021 |
A predictive model for astringency based on in vitro interactions between salivary proteins and (-)-Epigallocatechin gallate.
Topics: Adult; Catechin; Female; Fluorescence; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Models, Theoretical; Mucins; Protein Conformation; Salivary Proteins and Peptides; Spectrometry, Fluorescence; Taste; Tea; Temperature | 2021 |
Evaluation of green tea extract and epigallocatechin gallate effects on bisphenol A-induced vascular toxicity in isolated rat aorta and cytotoxicity in human umbilical vein endothelial cells.
Topics: Animals; Antioxidants; Aorta; Benzhydryl Compounds; Catechin; Chromatography, High Pressure Liquid; Human Umbilical Vein Endothelial Cells; Humans; Male; Phenols; Rats; Rats, Wistar; Signal Transduction; Tea | 2021 |
Adducts Derived from (-)-Epigallocatechin Gallate-Amadori Rearrangement Products in Aqueous Reaction Systems: Characterization, Formation, and Thermolysis.
Topics: Catechin; Glycation End Products, Advanced; Hot Temperature; Maillard Reaction; Mass Spectrometry; Molecular Structure; Water | 2020 |
Dehydroascorbic Acid Affects the Stability of Catechins by Forming Conjunctions.
Topics: Catechin; Dehydroascorbic Acid; Hydrolysis; Kinesis; Molecular Structure; Oxidation-Reduction; Tea; Temperature | 2020 |
EGCG Attenuates Renal Damage via Reversing Klotho Hypermethylation in Diabetic db/db Mice and HK-2 Cells.
Topics: Animals; Catechin; Cell Line; Cell Survival; Cytokines; Diabetes Mellitus, Experimental; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Glucuronidase; Humans; Inflammation Mediators; Kidney; Klotho Proteins; Mice, Inbred C57BL; Oxidative Stress; Promoter Regions, Genetic; Transforming Growth Factor beta1 | 2020 |
Comparative analysis of fecal metabolite profiles in HFD-induced obese mice after oral administration of huangjinya green tea extract.
Topics: Adipose Tissue, White; Animals; Blood Glucose; Camellia sinensis; Catechin; Diet, High-Fat; Feces; Humans; Insulin; Liver; Male; Metabolic Diseases; Mice; Mice, Inbred C57BL; Mice, Obese; Plant Extracts | 2020 |
Exogenous melatonin improves tea quality under moderate high temperatures by increasing epigallocatechin-3-gallate and theanine biosynthesis in Camellia sinensis L.
Topics: Caffeine; Camellia sinensis; Catechin; Climate; Glutamates; Melatonin; Photosynthesis; Plant Leaves; Tea; Temperature | 2020 |
New perspective to improve dentin-adhesive interface stability by using dimethyl sulfoxide wet-bonding and epigallocatechin-3-gallate.
Topics: Catechin; Dental Bonding; Dental Cements; Dentin; Dentin-Bonding Agents; Dimethyl Sulfoxide; Humans; Materials Testing; Resin Cements; Tensile Strength | 2020 |
Green tea extract-biomembrane interaction study: The role of its two major components, (-)-epigallocatechin gallate and (-)-epigallocatechin.
Topics: Catechin; Humans; Liposomes; Membrane Fluidity; Plant Extracts; Tea | 2021 |
The Physiochemical Properties and Adsorption Characteristics of Processed Pomelo Peel as a Carrier for Epigallocatechin-3-Gallate.
Topics: Adsorption; Catechin; Citrus; Fruit; Kinetics; Thermodynamics; Water Pollutants, Chemical | 2020 |
Effects of EGCG on depression-related behavior and serotonin concentration in a rat model of chronic unpredictable mild stress.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Catechin; Colon; Depression; Disease Models, Animal; Hippocampus; Male; Open Field Test; Rats; Rats, Wistar; Serotonin; Stress, Psychological; Swimming | 2020 |
Natural Compounds Modulate Drug Transporter Mediated Oral Cancer Treatment.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Catechin; Cell Line, Tumor; Cell Survival; Curcumin; Gefitinib; Humans; Kaplan-Meier Estimate; Mouth Neoplasms; Neoplasm Proteins; Photochemotherapy; Photosensitizing Agents | 2020 |
An Herbal Nanohybrid Formula of Epigallocatechin Gallate-Chitosan-Alginate Efficiently Restrict the Sexual Dysfunction Adverse Effect of
Topics: Adrenergic beta-Antagonists; Alginates; Animals; Catechin; Chitosan; Male; Nanostructures; Organ Size; Propranolol; Rats; Sexual Dysfunction, Physiological | 2020 |
Potential Modulation of Human NAD[P]H-Quinone Oxidoreductase 1 (NQO1) by EGCG and Its Metabolites-A Systematic Computational Study.
Topics: Catechin; Humans; Models, Molecular; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); Thermodynamics | 2020 |
The Effects of Resveratrol, Caffeine, β-Carotene, and Epigallocatechin Gallate (EGCG) on Amyloid-
Topics: Amyloid beta-Peptides; beta Carotene; Brain; Caffeine; Catechin; Cell Membrane; Microscopy, Fluorescence; Molecular Dynamics Simulation; Peptide Fragments; Resveratrol; Spectrophotometry, Ultraviolet; X-Ray Diffraction | 2020 |
Could applying gels containing chlorhexidine, epigallocatechin-3-gallate, or proanthocyanidin to control tooth wear progression improve bond strength to eroded dentin?
Topics: Catechin; Chlorhexidine; Composite Resins; Dental Bonding; Dentin; Dentin-Bonding Agents; Gels; Humans; Materials Testing; Proanthocyanidins; Resin Cements; Tensile Strength; Tooth Wear | 2020 |
[Epigallocatechin gallate induces
Topics: Antigens, CD; Apoptosis; Cadherins; Catechin; Cyclin-Dependent Kinase Inhibitor p21; Demethylation; Humans; Leukemia, Myeloid, Acute; Signal Transduction; Tumor Suppressor Protein p53 | 2020 |
Effects of Standardized Green Tea Extract and Its Main Component, EGCG, on Mitochondrial Function and Contractile Performance of Healthy Rat Cardiomyocytes.
Topics: Animals; Calcium-Binding Proteins; Catechin; Energy Metabolism; Male; Mitochondria; Myocytes, Cardiac; Oxidative Phosphorylation; Plant Extracts; Rats; Rats, Wistar; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Tea | 2020 |
Re-establishment of the epigenetic state and rescue of kinome deregulation in Ts65Dn mice upon treatment with green tea extract and environmental enrichment.
Topics: Animals; Camellia sinensis; Catechin; Chromatography, Liquid; Cognition; Disease Models, Animal; Down Syndrome; Epigenesis, Genetic; Hippocampus; Mice; Mice, Transgenic; Phosphorylation; Plant Extracts; Protein Interaction Maps; Proteomics; Tandem Mass Spectrometry | 2020 |
Computational and In Vitro Investigation of (-)-Epicatechin and Proanthocyanidin B2 as Inhibitors of Human Matrix Metalloproteinase 1.
Topics: Binding Sites; Catechin; Humans; Hydrophobic and Hydrophilic Interactions; Matrix Metalloproteinase 1; Matrix Metalloproteinase Inhibitors; Molecular Docking Simulation; Molecular Dynamics Simulation; Quantum Theory; Rifamycins; Solubility; Stereoisomerism; Thermodynamics | 2020 |
Epigallocatechin gallate induces chemopreventive effects on rats with diethylnitrosamine‑induced liver cancer via inhibition of cell division cycle 25A.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Catechin; cdc25 Phosphatases; Cell Cycle; Cell Proliferation; Cell Survival; Diethylnitrosamine; Disease Models, Animal; Hep G2 Cells; Humans; Liver; Liver Neoplasms; Male; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Tea; Transfection; Tumor Burden | 2020 |
The counteracting effects of (-)-Epigallocatechin-3-Gallate on the immobilization stress-induced adverse reactions in rat pancreas.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Catechin; Immobilization; Insulin Resistance; Male; Oxidative Stress; Pancreas; Rats; Rats, Wistar | 2021 |
Epigallocatechin-3-gallate (EGCG) addition as an antioxidant in a cryo-diluent media improves microscopic parameters, and fertility potential, and alleviates oxidative stress parameters of buffalo spermatozoa.
Topics: Animals; Antioxidants; Buffaloes; Catechin; Cattle; Cryopreservation; Fertility; Male; Oxidative Stress; Semen Preservation; Sperm Motility; Spermatozoa | 2020 |
Therapeutic potential of a novel prodrug of green tea extract in induction of apoptosis via ERK/JNK and Akt signaling pathway in human endometrial cancer.
Topics: Animals; Apoptosis; Catechin; Cell Proliferation; Endometrial Neoplasms; Female; Humans; Mice; Mice, Nude; Prodrugs; Proto-Oncogene Proteins c-akt; Signal Transduction; Tea | 2020 |
Effects of covalent modification with epigallocatechin-3-gallate on oleosin structure and ability to stabilize artificial oil body emulsions.
Topics: Catechin; Emulsions; Hydrophobic and Hydrophilic Interactions; Lipid Droplets; Molecular Structure; Plant Proteins | 2021 |
Paper 2. Epigallocatechin Gallate and Tannic Acid Based Formulations of Finasteride for Dermal Administration and Chemoembolization.
Topics: Administration, Cutaneous; Animals; Catechin; Finasteride; Swine; Tannins | 2021 |
Inhibition of starch digestion by flavonoids: Role of flavonoid-amylase binding kinetics.
Topics: alpha-Amylases; Animals; Catechin; Digestion; Enzyme Inhibitors; Flavonoids; Humans; Kinetics; Spectrometry, Fluorescence; Starch; Swine; Tea | 2021 |
The tea catechin epigallocatechin gallate inhibits NF-κB-mediated transcriptional activation by covalent modification.
Topics: Bronchi; Catechin; Cell Line; Epithelial Cells; Humans; Phosphorylation; Tea; Transcription Factor RelA; Transcriptional Activation | 2020 |
Part 1. Evaluation of Epigallocatechin Gallate or Tannic Acid Formulations of Hydrophobic Drugs for Enhanced Dermal and Bladder Uptake or for Local Anesthesia Effects.
Topics: Anesthesia, Local; Animals; Catechin; Pharmaceutical Preparations; Swine; Tannins; Urinary Bladder | 2021 |
Transcription Factor Nrf2 as a Potential Therapeutic Target for Prevention of Cytokine Storm in COVID-19 Patients.
Topics: Animals; Antioxidants; Betacoronavirus; Catechin; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Cytokines; Dimethyl Fumarate; Female; Humans; Immunosuppressive Agents; Inflammation; Isothiocyanates; Male; Mice; Molecular Targeted Therapy; NF-E2-Related Factor 2; Oxidative Stress; Pandemics; Pneumonia, Viral; Respiratory Distress Syndrome; Resveratrol; SARS-CoV-2; Signal Transduction; Sulfoxides; Thiosulfates | 2020 |
Epigallocatechin gallate and gallic acid affect colonization of abiotic surfaces by oral bacteria.
Topics: Actinomyces; Bacterial Adhesion; Biofilms; Catechin; Durapatite; Gallic Acid; Glass; Stainless Steel; Streptococcus mutans | 2020 |
Epigallocatechin-3-Gallate Reduces Visceral Adiposity Partly through the Regulation of Beclin1-Dependent Autophagy in White Adipose Tissues.
Topics: Adipose Tissue, White; Adiposity; Animals; Autophagy; Beclin-1; Catechin; Diet, High-Fat; Disease Models, Animal; Gene Expression Regulation, Developmental; Intra-Abdominal Fat; Male; Mice; Mice, Inbred C57BL; Obesity | 2020 |
Inhibition effect of epigallocatechin-3-gallate on the pharmacokinetics of calcineurin inhibitors, tacrolimus, and cyclosporine A, in rats.
Topics: Administration, Intravenous; Administration, Oral; Animals; Area Under Curve; Calcineurin Inhibitors; Catechin; Cyclosporine; Dose-Response Relationship, Drug; Herb-Drug Interactions; Immunosuppressive Agents; Male; Rats; Rats, Sprague-Dawley; Tacrolimus | 2021 |
Epigallocatechin Gallate (EGCG) Improves Anti-Angiogenic State, Cell Viability, and Hypoxia-Induced Endothelial Dysfunction by Downregulating High Mobility Group Box 1 (HMGB1) in Preeclampsia.
Topics: Angiogenesis Inhibitors; Catechin; Cell Hypoxia; Cell Line; Cell Survival; Down-Regulation; Female; HMGB1 Protein; Human Umbilical Vein Endothelial Cells; Humans; Pre-Eclampsia; Pregnancy | 2020 |
EGCG targeting Notch to attenuate renal fibrosis
Topics: Animals; Antioxidants; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Injections, Intraperitoneal; Mice; Mice, Inbred ICR; Random Allocation; Renal Insufficiency, Chronic; Signal Transduction; Smad3 Protein; Streptozocin; Transforming Growth Factor beta | 2020 |
Genomic predictions and genome-wide association studies based on RAD-seq of quality-related metabolites for the genomics-assisted breeding of tea plants.
Topics: Camellia sinensis; Catechin; Computational Biology; Genetic Association Studies; Genome, Plant; Genomics; Genotype; Linkage Disequilibrium; Phenotype; Plant Breeding; Polymorphism, Single Nucleotide; Sequence Analysis, DNA | 2020 |
Green tea derivative (-)-epigallocatechin-3-gallate (EGCG) confers protection against ionizing radiation-induced intestinal epithelial cell death both in vitro and in vivo.
Topics: Animals; Antioxidants; Catechin; Epithelial Cells; Mice; Radiation, Ionizing; Tea | 2020 |
Green tea polyphenol epigallocatechin-3-gallate alleviates nonalcoholic fatty liver disease and ameliorates intestinal immunity in mice fed a high-fat diet.
Topics: Adipose Tissue; Animals; Camellia sinensis; Catechin; Diet, High-Fat; Dietary Supplements; Humans; Intestines; Liver; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Plant Extracts; Polyphenols | 2020 |
Multifunctional nanoparticles for targeting the tumor microenvironment to improve synergistic drug combinations and cancer treatment effects.
Topics: Animals; Antineoplastic Agents; Catechin; Docetaxel; Drug Carriers; Drug Combinations; Drug Delivery Systems; Drug Synergism; Humans; Male; Mice, SCID; Multifunctional Nanoparticles; Prostatic Neoplasms; Tumor Microenvironment | 2020 |
EGCG Upregulates UCP
Topics: Adenosine Triphosphate; Animals; Apoptosis; Catechin; Cell Line; Cell Survival; Humans; Insulin; Interleukin-1beta; Islets of Langerhans; Membrane Potential, Mitochondrial; Mice; Mitochondria; Reactive Oxygen Species; Signal Transduction; Uncoupling Protein 3 | 2020 |
Protective effect of epigallocatechin-3-gallate (EGCG) on toxic metalloproteinases-mediated skin damage induced by Scyphozoan jellyfish envenomation.
Topics: Animals; Catechin; Cell Line; Cnidarian Venoms; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Scyphozoa; Skin Diseases | 2020 |
Epigallocatechin‑3‑gallate inhibits self‑renewal ability of lung cancer stem‑like cells through inhibition of CLOCK.
Topics: Animals; Catechin; Cell Line, Tumor; Cell Self Renewal; Circadian Rhythm; CLOCK Proteins; Female; Humans; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Up-Regulation; Wnt Signaling Pathway | 2020 |
Codelivery of epigallocatechin-3-gallate and diallyl trisulfide by near-infrared light-responsive mesoporous polydopamine nanoparticles for enhanced antitumor efficacy.
Topics: Allyl Compounds; Catechin; Indoles; Nanoparticles; Polymers; Sulfides | 2021 |
Epigallocatechin gallate mediated sandwich-like coating for mimicking endothelium with sustained therapeutic nitric oxide generation and heparin release.
Topics: Catechin; Cell Proliferation; Coated Materials, Biocompatible; Endothelial Cells; Endothelium; Heparin; Nitric Oxide; Vascular Endothelial Growth Factor A | 2021 |
Interaction of myofibrillar proteins and epigallocatechin gallate in the presence of transglutaminase in solutions.
Topics: Animals; Catechin; Drug Interactions; Fishes; Functional Food; Humans; Myofibrils; Rheology; Transglutaminases | 2020 |
Epigallocatechin Gallate Effectively Affects Senescence and Anti-SASP via
Topics: 3T3-L1 Cells; Animals; Anthocyanins; beta-Galactosidase; Bromodeoxyuridine; Catechin; Cell Shape; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Gene Expression Regulation; Genotype; Interleukin-6; Mice; NF-E2-Related Factor 2; Polyphenols; Resveratrol; RNA, Messenger; Sirtuin 3 | 2020 |
Role of green tea nanoparticles in process of tea cream formation - A new perspective.
Topics: Caffeine; Calorimetry; Catechin; Dynamic Light Scattering; Hydrophobic and Hydrophilic Interactions; Microscopy, Electron, Transmission; Nanoparticles; Tea | 2021 |
Maltoheptaoside hydrolysis with chromatographic detection and starch hydrolysis with reducing sugar analysis: Comparison of assays allows assessment of the roles of direct α-amylase inhibition and starch complexation.
Topics: Acarbose; alpha-Amylases; Amylopectin; Amylose; Catalytic Domain; Catechin; Chromatography, Ion Exchange; Flavones; Humans; Hydrolysis; Hydrolyzable Tannins; Oligosaccharides; Polyphenols; Salicylates; Starch; Sugars | 2021 |
Green tea extract rich in epigallocatechin gallate impairs alveolar bone loss in ovariectomized rats with experimental periodontal disease.
Topics: Animals; Antioxidants; Bone Density; Catechin; Female; Osteoporosis; Periodontal Diseases; Plant Extracts; Rats; Rats, Wistar | 2020 |
Natural P-gp inhibitor EGCG improves the acteoside absorption in Caco-2 cell monolayers and increases the oral bioavailability of acteoside in rats.
Topics: Administration, Oral; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Caco-2 Cells; Catechin; Glucosides; Half-Life; Humans; Phenols; Quercetin; Rats; Rats, Sprague-Dawley | 2020 |
Epigallocatechin Gallate Destabilizes α-Synuclein Fibril by Disrupting the E46-K80 Salt-Bridge and Inter-protofibril Interface.
Topics: alpha-Synuclein; Catechin; Humans; Lewy Bodies; Parkinson Disease | 2020 |
Use of leptin-conjugated phosphatidic acid liposomes with resveratrol and epigallocatechin gallate to protect dopaminergic neurons against apoptosis for Parkinson's disease therapy.
Topics: Apoptosis; Catechin; Dopaminergic Neurons; Humans; Leptin; Liposomes; Parkinson Disease; Phosphatidic Acids; Resveratrol | 2021 |
Effect of Epigallocatechin Gallate on Viability of Kudoa septempunctata.
Topics: Animals; Catechin; Cell Survival; Flounder; Flow Cytometry; Foodborne Diseases; Myxozoa | 2020 |
Epigallocatechin gallate-capped gold nanoparticles enhanced the tumor suppressors let-7a and miR-34a in hepatocellular carcinoma cells.
Topics: Carcinoma, Hepatocellular; Catechin; Gold; Humans; Liver Neoplasms; Metal Nanoparticles; MicroRNAs | 2020 |
The Effect of Angiotensin II, Retinoic Acid, EGCG, and Vitamin C on the Cardiomyogenic Differentiation Induction of Human Amniotic Fluid-Derived Mesenchymal Stem Cells.
Topics: Adult; Amniotic Fluid; Angiotensin II; Ascorbic Acid; Calcium Channels; Cardiac Myosins; Catechin; Cell Differentiation; Connexin 43; Epigenesis, Genetic; Female; Histones; Homeobox Protein Nkx-2.5; Humans; Mesenchymal Stem Cells; Myocytes, Cardiac; Myosin Heavy Chains; Oxidative Phosphorylation; Potassium Channels; Pregnancy; Pregnancy Trimester, Second; Primary Cell Culture; Signal Transduction; Tretinoin; Troponin T | 2020 |
Development and Optimization of Epigallocatechin-3-Gallate (EGCG) Nano Phytosome Using Design of Experiment (DoE) and Their In Vivo Anti-Inflammatory Studies.
Topics: Anti-Inflammatory Agents; Catechin; Chromatography, High Pressure Liquid; Drug Carriers; Gas Chromatography-Mass Spectrometry; Nanoparticles; Particle Size; Phytochemicals | 2020 |
Src Mediates Epigallocatechin-3-
Topics: Catechin; Cell Death; Cell Line, Tumor; Cell Survival; Enzyme Activation; Focal Adhesion Kinase 1; Humans; Models, Biological; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins c-akt; Signal Transduction; Sphingomyelin Phosphodiesterase; src-Family Kinases | 2020 |
Novel Hybrid Molecules Based on (-)-Epigallocatechin Gallate as Potent Anti-adipogenic Agents.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Anti-Obesity Agents; Catechin; Cell Differentiation; Cell Survival; Dose-Response Relationship, Drug; Lipids; Mice; Molecular Structure; Stereoisomerism; Structure-Activity Relationship | 2020 |
(-)-Epigallocatechin-3-gallate inhibits RANKL-induced osteoclastogenesis via downregulation of NFATc1 and suppression of HO-1-HMGB1-RAGE pathway.
Topics: Animals; Bone Density; Bone Density Conservation Agents; Bone Resorption; Catechin; Cathepsin K; Cell Differentiation; CSK Tyrosine-Protein Kinase; Femur; Gene Expression Regulation; Heme Oxygenase-1; HMGB1 Protein; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Osteoporosis; Primary Cell Culture; RANK Ligand; Receptor for Advanced Glycation End Products; Signal Transduction; Tibia; Treatment Outcome; Vacuolar Proton-Translocating ATPases | 2020 |
Dibenzoate esters of cis-tetralin-2,3-diol as analogs of (-)-epigallocatechin gallate: synthesis and crystal structure of anticancer drug candidates.
Topics: Antineoplastic Agents, Phytogenic; Catechin; Crystallography, X-Ray; Drug Design; Esterification; Hydrogen Bonding; Models, Molecular; Molecular Structure; Static Electricity; Tea; Tetrahydronaphthalenes | 2020 |
Could Dietary Factors Reduce COVID-19 Mortality Rates? Moderating the Inflammatory State.
Topics: Catechin; COVID-19; Curcumin; Cytokines; Diet; Humans; Inflammation; Linoleic Acid; Nutritional Physiological Phenomena | 2021 |
Double-crosslinked effect of TGase and EGCG on myofibrillar proteins gel based on physicochemical properties and molecular docking.
Topics: Animals; Biocatalysis; Catechin; Chemical Phenomena; Gels; Molecular Docking Simulation; Muscle Proteins; Transglutaminases | 2021 |
A molecular docking study of EGCG and theaflavin digallate with the druggable targets of SARS-CoV-2.
Topics: Antiviral Agents; Biflavonoids; Binding Sites; Catechin; Gallic Acid; Molecular Docking Simulation; SARS-CoV-2 | 2021 |
EGCG inhibits pressure overload-induced cardiac hypertrophy via the PSMB5/Nmnat2/SIRT6-dependent signalling pathways.
Topics: Animals; Cardiomegaly; Catechin; Cells, Cultured; Myocytes, Cardiac; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Sirtuins | 2021 |
Gel properties of transglutaminase-induced soy protein isolate-polyphenol complex: influence of epigallocatechin-3-gallate.
Topics: Biocatalysis; Catechin; Food Additives; Gels; Hot Temperature; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Polyphenols; Protein Structure, Secondary; Rheology; Soybean Proteins; Transglutaminases | 2021 |
Relationships between Plant Defense Inducer Activities and Molecular Structure of Gallomolecules.
Topics: Catechin; Flavonoids; Molecular Structure; Nicotiana; Phytophthora; Plant Diseases; Plant Leaves | 2020 |
Incorporating natural anti-inflammatory compounds into yeast glucan particles increases their bioactivity in vitro.
Topics: Anti-Inflammatory Agents; Antioxidants; Artemisinins; Catechin; Cytokines; Ellagic Acid; Flavonoids; Glucans; Monocytes; NF-kappa B; Resveratrol; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2021 |
Inhibition of d-glycero-β-d-manno-heptose 1-phosphate adenylyltransferase from Burkholderia pseudomallei by epigallocatechin gallate and myricetin.
Topics: Adenosine Triphosphate; Burkholderia pseudomallei; Catechin; Crystallography, X-Ray; Escherichia coli; Flavonoids; Inhibitory Concentration 50; Kinetics; Ligands; Mannose; Molecular Docking Simulation; Nucleotidyltransferases; Pyrans | 2021 |
L-EGCG-Mn nanoparticles as a pH-sensitive MRI contrast agent.
Topics: Animals; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Contrast Media; Gadolinium DTPA; Hydrogen-Ion Concentration; Liver Neoplasms; Magnetic Resonance Imaging; Manganese; Mice; Nanoparticles; Peritoneal Neoplasms; Proof of Concept Study | 2021 |
Probing the chemoprevention potential of the antidepressant fluoxetine combined with epigallocatechin gallate or kaempferol in rats with induced early stage colon carcinogenesis.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Antioxidants; Apoptosis; Catechin; Cell Proliferation; Chemoprevention; Colon; Colonic Neoplasms; Dimethylhydrazines; Fluoxetine; Kaempferols; Male; Phytotherapy; Rats, Sprague-Dawley | 2021 |
Epigallocatechin Gallate Reduces Homocysteine-Caused Oxidative Damages through Modulation SIRT1/AMPK Pathway in Endothelial Cells.
Topics: AMP-Activated Protein Kinases; Antioxidants; Apoptosis; Catechin; Dose-Response Relationship, Drug; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; NADPH Oxidases; Oxidative Stress; Phytotherapy; Protein Kinase C; Reactive Oxygen Species; Signal Transduction; Sirtuin 1; Tea | 2021 |
Effects of epigallocatechin gallate-enriched green tea extract capsules in uterine myomas: results of an observational study.
Topics: Adult; Capsules; Catechin; Female; Humans; Leiomyoma; Middle Aged; Plant Extracts; Quality of Life; Tea | 2021 |
Modulatory influences of antiviral bioactive compounds on cell viability, mRNA and protein expression of cytochrome P450 3A4 and P-glycoprotein in HepG2 and HEK293 cells.
Topics: Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Catechin; Cell Survival; Cytochrome P-450 CYP3A; Ellagic Acid; Gene Expression Regulation; HEK293 Cells; Hep G2 Cells; Humans; Luteolin; Plants; Protein Binding; RNA, Messenger | 2021 |
Effects of epigallocatechin-3-gallate and acyclovir on herpes simplex virus type 1 infection in oral epithelial cells.
Topics: Acyclovir; Antiviral Agents; Catechin; Epithelial Cells; Herpesvirus 1, Human; Humans | 2021 |
Epigallocatechin-3-Gallate Suppresses the Expression of TNF-α-Induced MMP-1 via MAPK/ERK Signaling Pathways in Human Dermal Fibroblasts.
Topics: Antioxidants; Catechin; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Reactive Oxygen Species; Skin Aging; Tumor Necrosis Factor-alpha | 2021 |
Epigallocatechin gallate and coenzyme Q10 attenuate cisplatin-induced hepatotoxicity in rats via targeting mitochondrial stress and apoptosis.
Topics: Animals; Apoptosis; Catechin; Chemical and Drug Induced Liver Injury; Cisplatin; Hepatocytes; Liver; Male; Mitochondria, Liver; Oxidative Stress; Rats; Rats, Wistar; Ubiquinone | 2021 |
Improved Stability and Targeted Cytotoxicity of Epigallocatechin-3-Gallate Palmitate for Anticancer Therapy.
Topics: Antioxidants; Catechin; Hydrogen Peroxide; Palmitates; Reactive Oxygen Species | 2021 |
Chocolate as a food matrix reduces the bioavailability of galloylated catechins from green tea in healthy women.
Topics: Adult; Animals; Biological Availability; Catechin; Chocolate; Female; Food; Humans; Male; Models, Animal; Rats; Rats, Wistar; Reference Values; Tea; Young Adult | 2021 |
Epigallocatechin-3-gallate Alleviates Vanadium-Induced Reduction of Antioxidant Capacity via Keap1-Nrf2-sMaf Pathway in the Liver, Kidney, and Ovary of Laying Hens.
Topics: Animal Feed; Animals; Antioxidants; Catechin; Chickens; Diet; Dietary Supplements; Female; Kelch-Like ECH-Associated Protein 1; Kidney; Liver; NF-E2-Related Factor 2; Ovary; Vanadium | 2021 |
Therapeutic effects of biochanin A, phloretin, and epigallocatechin-3-gallate in reducing oxidative stress in arsenic-intoxicated mice.
Topics: Animals; Antioxidants; Arsenic; Catechin; Genistein; Humans; Lipid Peroxidation; Liver; Male; Mice; Oxidative Stress; Phloretin; Protein Carbonylation; Sperm Motility | 2021 |
Epigallocatechin-3-gallate reduces liver and immune system damage in Acinetobacter baumannii-loaded mice with restraint stress.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Antioxidants; Catechin; Disease Models, Animal; Female; Immune System; Inflammation; Liver Diseases; Male; Mice; Mice, Inbred ICR; Oxidative Stress | 2021 |
Effects of stem removal on physicochemical properties and sensory quality of tencha beverages (Camellia sinensis; Chuanxiaoye).
Topics: Beverages; Caffeine; Camellia sinensis; Catechin; Chemical Phenomena; Chlorophyll; Odorants; Phenols; Plant Leaves; Plant Stems; Quality Control; Sensation; Taste; Tea | 2021 |
Modulators of Neuroinflammation Have a Beneficial Effect in a Lafora Disease Mouse Model.
Topics: Animals; Biomarkers; Brain; Catechin; Disease Models, Animal; Gliosis; Glucans; Hippocampus; Inclusion Bodies; Inflammation; Lafora Disease; Mice, Inbred C57BL; Mice, Knockout; Microglia; Motor Activity; Nerve Degeneration; Neurons; Phenotype; Propranolol; Ubiquitin-Protein Ligases | 2021 |
Mass spectrometry in the study of molecular complexes between 5-fluorouracil and catechins.
Topics: Antineoplastic Agents; Catechin; Chromatography, Liquid; Flow Injection Analysis; Fluorouracil; Herb-Drug Interactions; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tea | 2021 |
Epigallocatechin Gallate Ameliorates the Effects of Prenatal Alcohol Exposure in a Fetal Alcohol Spectrum Disorder-Like Mouse Model.
Topics: Animals; Astrocytes; Biomarkers; Catechin; Cell Differentiation; Disease Models, Animal; Doublecortin Protein; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Immunohistochemistry; Male; Maternal Exposure; Mice; Neurogenesis; Neurons; Oxidative Stress; Placenta; Pregnancy; Prenatal Exposure Delayed Effects | 2021 |
Synthesis, Stability, and Antidiabetic Activity Evaluation of (-)-Epigallocatechin Gallate (EGCG) Palmitate Derived from Natural Tea Polyphenols.
Topics: alpha-Amylases; alpha-Glucosidases; Bacillus licheniformis; Catechin; Enzyme Inhibitors; Hypoglycemic Agents; Ligands; Molecular Docking Simulation; Palmitates; Polyphenols; Saccharomyces cerevisiae; Tea | 2021 |
The inhibitory effects of PGG and EGCG against the SARS-CoV-2 3C-like protease.
Topics: Binding Sites; Catechin; Coronavirus 3C Proteases; COVID-19; Drug Evaluation, Preclinical; Humans; Hydrolyzable Tannins; Kinetics; Models, Molecular; Molecular Docking Simulation; Molecular Structure; Pandemics; Protease Inhibitors; Protein Binding; Protein Domains; SARS-CoV-2; Virus Replication | 2022 |
Three flavanols delay starch digestion by inhibiting α-amylase and binding with starch.
Topics: alpha-Amylases; Biflavonoids; Binding Sites; Catechin; Glucose; Glycoside Hydrolase Inhibitors; Hydrolysis; Kinetics; Maltose; Molecular Docking Simulation; Proanthocyanidins; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Starch; Substrate Specificity; Thermodynamics; Trisaccharides | 2021 |
Green Tea Polyphenol Microparticles Based on the Oxidative Coupling of EGCG Inhibit Amyloid Aggregation/Cytotoxicity and Serve as a Platform for Drug Delivery.
Topics: Amyloid; Catechin; Humans; Oxidative Coupling; Pharmaceutical Preparations; Polyphenols; Tea | 2020 |
Epigallocatechin-3-gallate Enhances the Efficacy of MicroRNA-34a Mimic and MicroRNA-93 Inhibitor Co-transfection in Prostate Cancer Cell Line.
Topics: Catechin; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Male; MicroRNAs; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Transfection | 2020 |
Epigallocatechin-3-gallate increases autophagic activity attenuating TGF-β1-induced transformation of human Tenon's fibroblasts.
Topics: Actins; Adenoviridae; Antioxidants; Autophagy; Blotting, Western; Catechin; Cell Transdifferentiation; Cells, Cultured; Green Fluorescent Proteins; Humans; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Microtubule-Associated Proteins; Myofibroblasts; Sequestosome-1 Protein; Tenon Capsule; Transfection; Transforming Growth Factor beta1 | 2021 |
Effects of epigallocatechin gallate (EGCG) on the biological properties of human dental pulp stem cells and inflammatory pulp tissue.
Topics: Animals; Apoptosis; Catechin; Cell Hypoxia; Cells, Cultured; Dental Pulp; Humans; Inflammation; Rats; Rats, Sprague-Dawley; Stem Cells | 2021 |
Epigallocatechin gallate protects the human lens epithelial cell survival against UVB irradiation through AIF/endo G signalling pathways
Topics: Apoptosis; Apoptosis Inducing Factor; Cataract; Catechin; Cell Line; Cell Survival; Endodeoxyribonucleases; Epithelial Cells; Humans; Lens, Crystalline; Oxidative Stress; Signal Transduction; Ultraviolet Rays | 2021 |
Protective Effect of Epigallocatechin-3-Gallate in Hydrogen Peroxide-Induced Oxidative Damage in Chicken Lymphocytes.
Topics: Animals; Antioxidants; Catechin; Chickens; Female; Hydrogen Peroxide; Lymphocytes; Oxidants; Oxidative Stress; Protective Agents | 2020 |
Metabolic and Functional Improvements in a Patient with Charcot-Marie-Tooth Disease Type 2 after EGCG Administration: A Case Report.
Topics: Aryldialkylphosphatase; Catechin; Charcot-Marie-Tooth Disease; Female; Hand Strength; Humans; Male; Walk Test | 2021 |
Toxic effects of dietary copper and EGCG on bioaccumulation, antioxidant enzyme and immune response of Korean bullhead, Pseudobagrus fulvidraco.
Topics: Animal Feed; Animals; Antioxidants; Bioaccumulation; Catechin; Catfishes; Copper; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Immunity; Inactivation, Metabolic; Random Allocation; Republic of Korea; Water Pollutants, Chemical | 2021 |
[Effects of swimming and epigallocatechin gallate on interstitial proteins expression of myocardium from type 2 diabetic rats].
Topics: Animals; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Male; Myocardium; Rats; Rats, Sprague-Dawley; Swimming; Transforming Growth Factor beta1 | 2021 |
Epigallocatechin-3-gallate prevents inflammation and diabetes -Induced glucose tolerance through inhibition of NLRP3 inflammasome activation.
Topics: Animals; Anti-Inflammatory Agents; Bone Marrow; Catechin; Cells, Cultured; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Glucose Tolerance Test; Humans; Inflammasomes; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis | 2021 |
Comparing the inhibitory abilities of epigallocatechin-3-gallate and gallocatechin gallate against tyrosinase and their combined effects with kojic acid.
Topics: Catechin; Drug Synergism; Hydrogen Bonding; Molecular Conformation; Molecular Docking Simulation; Monophenol Monooxygenase; Pyrones | 2021 |
Epigallocatechin-3-gallate, an active ingredient of Traditional Chinese Medicines, inhibits the 3CLpro activity of SARS-CoV-2.
Topics: Adult; Antiviral Agents; Catechin; China; Coronavirus 3C Proteases; COVID-19; COVID-19 Drug Treatment; Female; Fluorescence Resonance Energy Transfer; Humans; Male; Medicine, Chinese Traditional; Middle Aged; Molecular Docking Simulation; Pandemics; Protease Inhibitors; Retrospective Studies; SARS-CoV-2; Virus Replication; Young Adult | 2021 |
Evaluation of the anti-oxidative and ROS scavenging properties of biomaterials coated with epigallocatechin gallate for tissue engineering.
Topics: Antioxidants; Biocompatible Materials; Catechin; Humans; Hydrogen Peroxide; Oxidative Stress; Reactive Oxygen Species; Tissue Engineering | 2021 |
Drinking Green Tea: Despite the Risks Due to Mycotoxins, Is It Possible to Increase the Associated Health Benefits?
Topics: Camellia sinensis; Catechin; Consumer Product Safety; Dietary Exposure; Food Microbiology; Humans; Mycotoxins; Portugal; Recommended Dietary Allowances; Risk Assessment; Tea | 2021 |
Effects of (-)-Epigallocatechin-3-gallate on the Functional and Structural Properties of Soybean Protein Isolate.
Topics: Catechin; Circular Dichroism; Hydrogen Bonding; Molecular Docking Simulation; Protein Binding; Soybean Proteins | 2021 |
Sustained release of epigallocatechin-3-gallate from chitosan-based scaffolds to promote osteogenesis of mesenchymal stem cell.
Topics: Alginates; Biological Availability; Catechin; Cell Differentiation; Cell Proliferation; Cell Survival; Cells, Cultured; Chitosan; Delayed-Action Preparations; Humans; Mesenchymal Stem Cells; Microscopy, Electron; Nanocapsules; Nanoparticles; Osteogenesis; Spectroscopy, Fourier Transform Infrared; Tissue Engineering; Tissue Scaffolds; X-Ray Diffraction | 2021 |
EGCG binds intrinsically disordered N-terminal domain of p53 and disrupts p53-MDM2 interaction.
Topics: Apoptosis; Binding Sites; Catechin; Cell Line, Tumor; Epitopes; Humans; Protein Binding; Proto-Oncogene Proteins c-mdm2; Scattering, Small Angle; Tea; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases; Ubiquitination; X-Ray Diffraction | 2021 |
Proliferation of MDA-MB-231 can be suppressed by dimeric-epigallocatechin gallate through competitive inhibition of amphiregulin-epidermal growth factor receptor signaling.
Topics: Amphiregulin; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dimerization; ErbB Receptors; Female; Humans; MCF-7 Cells; Signal Transduction | 2021 |
High internal phase pickering emulsions stabilized by pea protein isolate-high methoxyl pectin-EGCG complex: Interfacial properties and microstructure.
Topics: Catechin; Emulsions; Pea Proteins; Pectins; Rheology; Viscosity; Water; Wettability | 2021 |
EGCG Regulates Cell Apoptosis of Human Umbilical Vein Endothelial Cells Grown on 316L Stainless Steel for Stent Implantation.
Topics: Apoptosis; Catechin; Cell Proliferation; Dose-Response Relationship, Drug; Human Umbilical Vein Endothelial Cells; Humans; Molecular Structure; Stainless Steel; Stents; Structure-Activity Relationship | 2021 |
(-)-Epigallocatechin-3-O-gallate at a high concentration may induce lipolysis via ATP consumption by activation of stress defense mechanisms.
Topics: Adenosine Triphosphate; Catechin; Cell Line, Tumor; Dose-Response Relationship, Drug; Energy Metabolism; Gene Expression Regulation; Humans; Lipolysis; Oxidative Stress; RNA, Messenger | 2021 |
Fabrication of oral nanovesicle in-situ gel based on Epigallocatechin gallate phospholipid complex: Application in dental anti-caries.
Topics: Administration, Oral; Anti-Bacterial Agents; Bacterial Adhesion; Biofilms; Cariostatic Agents; Catechin; Dental Caries; Drug Carriers; Drug Compounding; Drug Liberation; Drug Stability; Gels; Kinetics; Nanoparticles; Phospholipids; Staphylococcus aureus | 2021 |
Epigallocatechin-3-gallate inhibits proliferation and triggers apoptosis in colon cancer via the hedgehog/phosphoinositide 3-kinase pathways.
Topics: Animals; Apoptosis; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colonic Neoplasms; Female; Hedgehog Proteins; Humans; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction | 2021 |
()-Epigallocatechin-3-Gallate Inhibits EBV Lytic Replication via Targeting LMP1-Mediated MAPK Signal Axes.
Topics: Antiviral Agents; Catechin; Cell Line, Tumor; Epstein-Barr Virus Infections; Herpesvirus 4, Human; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Mutation; Phosphorylation; Promoter Regions, Genetic; Tumor Suppressor Protein p53; Viral Matrix Proteins; Virus Replication | 2021 |
Green tea extracts containing epigallocatechin-3-gallate modulate facial development in Down syndrome.
Topics: Adolescent; Animals; Catechin; Child; Child, Preschool; Dietary Supplements; Disease Models, Animal; Down Syndrome; Face; Female; Humans; Infant; Male; Mice; Plant Extracts; Tea | 2021 |
Effect of squid pen chitooligosaccharide and epigallocatechin gallate on discoloration and shelf-life of yellowfin tuna slices during refrigerated storage.
Topics: Animals; Catechin; Chitin; Chitosan; Color; Decapodiformes; Metmyoglobin; Myoglobin; Oligosaccharides; Seafood; Tuna | 2021 |
Epigallocatechin-3-gallate/nanohydroxyapatite platform delivery approach to adhesive-dentin interface stability.
Topics: Adhesives; Catechin; Dental Bonding; Dentin; Materials Testing; Microscopy, Electron, Scanning; Resin Cements; Streptococcus mutans; Tensile Strength | 2021 |
Epigallocatechin-3-gallate exhibits antiviral effects against the duck Tembusu virus via blocking virus entry and upregulating type I interferons.
Topics: Animals; Antiviral Agents; Catechin; Cell Line; China; Cricetinae; Ducks; Flavivirus; Flavivirus Infections; Interferon Type I; Poultry Diseases; Survival Analysis; Treatment Outcome; Up-Regulation; Virus Internalization | 2021 |
Competitive interactions among tea catechins, proteins, and digestive enzymes modulate in vitro protein digestibility, catechin bioaccessibility, and antioxidant activity of milk tea beverage model systems.
Topics: Antioxidants; Beverages; Catechin; Tea | 2021 |
Curcumin promotes cell cycle arrest and apoptosis of acute myeloid leukemia cells by inactivating AKT.
Topics: Animals; Apoptosis; Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Curcumin; Genistein; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred NOD; Mice, SCID; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; U937 Cells | 2021 |
Semaphorin 3A contributes to sepsis‑induced immunosuppression by impairing CD4
Topics: Animals; Antioxidants; Catechin; CD4-Positive T-Lymphocytes; Cells, Cultured; Clonal Anergy; Humans; Immune Tolerance; Lipopolysaccharides; Male; Mice, Inbred C57BL; Multiple Organ Failure; NF-kappa B; Semaphorin-3A; Sepsis; Signal Transduction | 2021 |
Identification of Potential HCV Inhibitors Based on the Interaction of Epigallocatechin-3-Gallate with Viral Envelope Proteins.
Topics: Antiviral Agents; Catechin; Hepacivirus; Hepatitis C; Humans; Ligands; Molecular Docking Simulation; Polyphenols; Tea; Viral Envelope; Viral Envelope Proteins; Virus Internalization | 2021 |
KCNQ5 Potassium Channel Activation Underlies Vasodilation by Tea.
Topics: Animals; Binding Sites; Catechin; KCNQ Potassium Channels; KCNQ1 Potassium Channel; Male; Membrane Potentials; Mesenteric Arteries; Milk; Molecular Docking Simulation; Myography; Oocytes; Patch-Clamp Techniques; Plant Extracts; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Isoforms; Rats; Rats, Wistar; Tea; Tissue Culture Techniques; Vasodilation; Xenopus laevis | 2021 |
Epigallocatechin-3-Gallate Dampens Non-Alcoholic Fatty Liver by Modulating Liver Function, Lipid Profile and Macrophage Polarization.
Topics: Adipose Tissue; Animals; Body Weight; Catechin; Cholesterol; Diet, High-Fat; Disease Models, Animal; Lipids; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Organ Size | 2021 |
Paternal Inheritance of Bisphenol A Cardiotoxic Effects: The Implications of Sperm Epigenome.
Topics: Acetylation; Animals; Benzhydryl Compounds; Cardiotoxicity; Catechin; Embryo, Nonmammalian; Epigenesis, Genetic; Epigenome; Histones; Male; Paternal Inheritance; Phenols; Spermatozoa; Transcriptome; Zebrafish; Zebrafish Proteins | 2021 |
Epigallocatechin gallate affects the proliferation of human alveolar osteoblasts and periodontal ligament cells, as well as promoting cell differentiation by regulating PI3K/Akt signaling pathway.
Topics: Catechin; Cell Differentiation; Cell Proliferation; Cells, Cultured; Humans; Osteoblasts; Osteogenesis; Periodontal Ligament; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction | 2021 |
(-)-Epigallocatechin-3-gallate inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing NF-κB and MAPK signaling pathways.
Topics: Animals; Catechin; MAP Kinase Signaling System; Mice; NF-kappa B; Osteoclasts; Osteogenesis; RANK Ligand; RAW 264.7 Cells; Receptor Activator of Nuclear Factor-kappa B | 2021 |
Impact of green tea on the deleterious cardiometabolic effects of 7-days unhealthy lifestyle in young healthy males.
Topics: Adult; Blood Glucose; Cardiovascular Diseases; Catechin; Double-Blind Method; Humans; Insulin; Life Style; Male; Middle Aged; Postprandial Period; Tea; Young Adult | 2021 |
Epigallocatechin-3-gallate exhibits immunomodulatory effects in human primary T cells.
Topics: Anti-Inflammatory Agents; Catechin; Cell Survival; Cells, Cultured; Cytokines; Down-Regulation; Humans; Inflammation; Lymphocyte Activation; MAP Kinase Signaling System; T-Lymphocytes; Transcription Factor AP-1 | 2021 |
Molecular hybridization based on (-)-epigallocatechin gallate as a new class of antiglycation agents.
Topics: Animals; Catechin; Cattle; Chemistry Techniques, Synthetic; Fructose; Glucose; Glycation End Products, Advanced; Glycosylation; Magnetic Resonance Spectroscopy; Plasma Gases; Resorcinols; Serum Albumin, Bovine; Solutions | 2021 |
Epigallocatechin-3-Gallate Promotes the in vitro Maturation and Embryo Development Following IVF of Porcine Oocytes.
Topics: Animals; Benzothiazoles; Catechin; Dose-Response Relationship, Drug; Embryonic Development; Molecular Structure; Oocytes; Oxidative Stress; Reactive Oxygen Species; Structure-Activity Relationship; Sulfonic Acids; Swine | 2021 |
Chitosan-PEG-folate-Fe(III) complexes as nanocarriers of epigallocatechin-3-gallate.
Topics: Catechin; Chitosan; Delayed-Action Preparations; Drug Compounding; Drug Stability; Ferric Compounds; Folic Acid; Nanoparticles; Particle Size; Polyethylene Glycols; Surface Properties | 2020 |
Preparation of β-lactoglobulin/gum arabic complex nanoparticles for encapsulation and controlled release of EGCG in simulated gastrointestinal digestion model.
Topics: Catechin; Delayed-Action Preparations; Digestion; Gum Arabic; Lactoglobulins; Nanoparticles; Particle Size; Static Electricity | 2021 |
CCN5 activation by free or encapsulated EGCG is required to render triple-negative breast cancer cell viability and tumor progression.
Topics: Animals; Apoptosis; Catechin; CCN Intercellular Signaling Proteins; Cell Line, Tumor; Cell Survival; Female; Humans; Mice; Nanoparticle Drug Delivery System; Repressor Proteins; Spheroids, Cellular; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays | 2021 |
Epigallocatechin gallate for medical management of the abdominal aortic aneurysm.
Topics: Aortic Aneurysm, Abdominal; Apoptosis; Catechin; Humans | 2021 |
Catechins in green tea powder (matcha) are heat-stable scavengers of acrolein, a lipid peroxide-derived reactive carbonyl species.
Topics: Acrolein; Aldehydes; Catechin; Chromatography, High Pressure Liquid; Cooking; Free Radical Scavengers; Hot Temperature; Mass Spectrometry; Plant Extracts; Powders; Tea | 2021 |
Epigallocatechin gallate alters leukotoxin secretion and Aggregatibacter actinomycetemcomitans virulence.
Topics: Aggregatibacter actinomycetemcomitans; Anti-Bacterial Agents; Bacterial Toxins; Catechin; Coculture Techniques; Dose-Response Relationship, Drug; Exotoxins; Humans; Periodontitis; Virulence | 2021 |
EGCG Inhibits Adipose-Derived Mesenchymal Stem Cells Differentiation into Adipocytes and Prevents a STAT3-Mediated Paracrine Oncogenic Control of Triple-Negative Breast Cancer Cell Invasive Phenotype.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Adiponectin; Animals; Catechin; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferation; Culture Media, Conditioned; Female; Humans; Leptin; Mesenchymal Stem Cells; Mice; Paracrine Communication; STAT3 Transcription Factor; Tea; Triple Negative Breast Neoplasms | 2021 |
Epigallocatechin-3-Gallate Protects Pro-Acinar Epithelia Against Salivary Gland Radiation Injury.
Topics: Acinar Cells; Animals; Apoptosis; Catechin; Cell Line; Epithelial Cells; Epithelium; Humans; Immunohistochemistry; Oxidative Stress; Radiation Injuries; Radiation-Protective Agents; Salivary Glands | 2021 |
Epigallocatechin-3-Gallate-Loaded Liposomes Favor Anti-Inflammation of Microglia Cells and Promote Neuroprotection.
Topics: Animals; Anti-Inflammatory Agents; Behavior, Animal; Biomarkers; Catechin; Cell Line; Cell Shape; Cell Survival; Cytokines; Lipopolysaccharides; Liposomes; Mice; Microglia; Neuroprotection; Nitric Oxide | 2021 |
Identify the interactions between phytochemicals and proteins in the complicated food matrix.
Topics: Animals; Antioxidants; Caffeine; Caseins; Catechin; Coffee; Milk; Photochemical Processes; Phytochemicals; Soy Milk | 2021 |
Low-dose vardenafil potentiates the protective effect of (-)-epigallocatechin gallate on cardiomyocytes.
Topics: Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Catechin; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Synergism; Hydrogen Peroxide; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Signal Transduction; Vardenafil Dihydrochloride | 2020 |
Inhibitory effects of epigallocatechin gallate (EGCG) combined with zinc sulfate and silver nanoparticles on avian influenza A virus subtype H5N1.
Topics: Animals; Antiviral Agents; Catechin; Cells, Cultured; Chlorocebus aethiops; Dose-Response Relationship, Drug; Influenza A Virus, H5N1 Subtype; Metal Nanoparticles; Microbial Sensitivity Tests; Silver; Vero Cells; Zinc Sulfate | 2021 |
The green tea catechin epigallocatechin gallate inhibits SARS-CoV-2 infection.
Topics: Animals; Antiviral Agents; Betacoronavirus; Catechin; Cell Survival; Chlorocebus aethiops; COVID-19; HEK293 Cells; Humans; Lentivirus; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Tea; Vero Cells; Virus Attachment; Virus Replication | 2021 |
Conjugation of (-)-epigallocatechin-3-gallate and protein isolate from large yellow croaker (Pseudosciaena crocea) roe: improvement of antioxidant activity and structural characteristics.
Topics: Animals; Antioxidants; Catechin; Female; Fish Proteins; Food Preservation; Food Preservatives; Ovary; Ovum; Perciformes; Protein Conformation | 2021 |
The diversity in sensitivity of TRPA1 and TRPV1 of various animals to polyphenols.
Topics: Ambystoma mexicanum; Amphibians; Animals; Calcium; Catechin; Chickens; Flavonoids; HEK293 Cells; Humans; Mice; Neurons; Oryzias; Polyphenols; Rats; Snakes; Tannins; TRPA1 Cation Channel; TRPV Cation Channels; Zebrafish; Zebrafish Proteins | 2021 |
Enhancement of angiogenin inhibition by polyphenol-capped gold nanoparticles.
Topics: Binding Sites; Binding, Competitive; Catechin; Enzymes; Gold; Humans; Kinetics; Metal Nanoparticles; Molecular Docking Simulation; Polyphenols; Recombinant Proteins; Ribonuclease, Pancreatic; Spectrometry, Fluorescence | 2021 |
Epigallocatechin-3-gallate inhibits the growth of three-dimensional in vitro models of neuroblastoma cell SH-SY5Y.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Culture Techniques; Cell Proliferation; Coculture Techniques; Human Umbilical Vein Endothelial Cells; Humans; Neuroblastoma; Tumor Cells, Cultured | 2021 |
Combination of resveratrol and green tea epigallocatechin gallate induces synergistic apoptosis and inhibits tumor growth
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Carcinogenesis; Catechin; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Head and Neck Neoplasms; Humans; Mice; Resveratrol; Signal Transduction; Tea; Xenograft Model Antitumor Assays | 2021 |
Uterine fibroids treatment: do we have new valid alternative? Experiencing the combination of vitamin D plus epigallocatechin gallate in childbearing age affected women.
Topics: Administration, Oral; Adult; Antineoplastic Agents; Catechin; Female; Humans; Leiomyoma; Myoma; Tablets; Uterine Neoplasms; Vitamin D | 2021 |
Identification of regulated proteins by epigallocatechin gallate treatment in an ischemic cerebral cortex animal model: a proteomics approach.
Topics: Animals; Catechin; Cerebral Cortex; Disease Models, Animal; Infarction, Middle Cerebral Artery; Proteomics; Rats; Rats, Sprague-Dawley; Rodent Diseases | 2021 |
Screening of Inhibitors Targeting Heat Shock Protein 47 Involved in the Development of Idiopathic Pulmonary Fibrosis.
Topics: Catechin; Dose-Response Relationship, Drug; Drug Development; Drug Evaluation, Preclinical; HSP47 Heat-Shock Proteins; Humans; Idiopathic Pulmonary Fibrosis; Molecular Structure; Structure-Activity Relationship | 2021 |
Oral administration of EGCG solution equivalent to daily achievable dosages of regular tea drinkers effectively suppresses miR483-3p induced metastasis of hepatocellular carcinoma cells in mice.
Topics: Animals; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Neoplasm Metastasis; Reactive Oxygen Species; Solutions; Tea; Transduction, Genetic | 2021 |
Epigallocatechin Gallate Enhances Inhibition Effect of DDP on the Proliferation of Gastric Cancer BGC-823 Cells by Regulating p19Arf-p53-p21Cip1 Signaling Pathway.
Topics: Antineoplastic Agents; Antioxidants; Catechin; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Cisplatin; Cyclin-Dependent Kinase Inhibitor p19; Cyclin-Dependent Kinase Inhibitor p21; Humans; Signal Transduction; Stomach Neoplasms; Tumor Suppressor Protein p53 | 2021 |
(-)-Epigallocatechin-3-gallate induces apoptosis and differentiation in leukaemia by targeting reactive oxygen species and PIN1.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Catechin; Cell Differentiation; Humans; Leukemia, Experimental; Leukemia, Promyelocytic, Acute; Mice, Transgenic; NIMA-Interacting Peptidylprolyl Isomerase; Reactive Oxygen Species; Retinoic Acid Receptor alpha; Spleen | 2021 |
Distinct Classes of Flavonoids and Epigallocatechin Gallate, Polyphenol Affects an Oncogenic Mutant p53 Protein, Cell Growth and Invasion in a TNBC Breast Cancer Cell Line.
Topics: Biological Products; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; Flavonoids; Humans; Mutant Proteins; Mutation; Neoplasm Invasiveness; Oncogenes; Polyphenols; Proto-Oncogene Proteins c-ets; RNA, Messenger; Transcription, Genetic; Triple Negative Breast Neoplasms; Tumor Suppressor Protein p53 | 2021 |
Role of Haptoglobin as a Marker of Muscular Improvement in Patients with Multiple Sclerosis after Administration of Epigallocatechin Gallate and Increase of Beta-Hydroxybutyrate in the Blood: A Pilot Study.
Topics: 3-Hydroxybutyric Acid; Adult; Biomarkers; Catechin; Female; Haptoglobins; Humans; Interleukin-6; Male; Middle Aged; Multiple Sclerosis; Muscle, Skeletal; Pilot Projects | 2021 |
A green tea extract and epigallocatechin-3-gallate attenuate the deleterious effects of irinotecan in an oral epithelial cell model.
Topics: Catechin; Epithelial Cells; Irinotecan; Plant Extracts; Tea | 2021 |
The Stability of Dentin Surface Biobarrier Consisting of Mesoporous Delivery System on Dentinal Tubule Occlusion and Streptococcus Mutans Biofilm Inhibition.
Topics: Acids; Adsorption; Biofilms; Calcium; Caseins; Catechin; Cell Death; Colony Count, Microbial; Dental Pulp; Dentin; Humans; Nanoparticles; Nitrogen; Permeability; Phosphorus; Porosity; Silicon Dioxide; Streptococcus mutans | 2021 |
Epigallocatechin-3-Gallate Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via Inhibition of Apoptosis and Promotion of Autophagy through the ROS/MAPK Signaling Pathway.
Topics: Animals; Apoptosis; Autophagy; Catechin; Diet, High-Fat; Disease Models, Animal; Disease Progression; Humans; Male; Mice; Mitogen-Activated Protein Kinases; Non-alcoholic Fatty Liver Disease; Signal Transduction | 2021 |
Effect of epigallocatechin-3-gallate and thermal cycling on the bond strength of resin cements to the root dentin.
Topics: Animals; Catechin; Cattle; Dental Bonding; Dentin; Materials Testing; Post and Core Technique; Resin Cements | 2021 |
Natural antioxidants enhance the power of physical and mental activities versus risk factors inducing progression of Alzheimer's disease in rats.
Topics: Alzheimer Disease; Animals; Antioxidants; Ascorbic Acid; Catechin; Disease Models, Animal; Disease Progression; Male; Mental Health; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Risk Factors; Selenium; Vitamin E | 2021 |
Combined use of epigallocatechin-3-gallate (EGCG) and caffeine in low doses exhibits marked anti-obesity synergy through regulation of gut microbiota and bile acid metabolism.
Topics: Animals; Anti-Obesity Agents; Bile Acids and Salts; Caffeine; Catechin; Cholesterol 7-alpha-Hydroxylase; Drug Synergism; Drug Therapy, Combination; Fatty Acids, Volatile; Feces; Gastrointestinal Microbiome; Liver; Male; Obesity; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled | 2021 |
Is nutraceutical supplementation appropriate for COVID-19 management?
Topics: Berberine; Catechin; COVID-19; Curcumin; Dietary Supplements; Humans; Lactobacillus; NF-E2-Related Factor 2; Receptor, Angiotensin, Type 1; SARS-CoV-2 | 2021 |
EGCG Induces Pro-inflammatory Response in Macrophages to Prevent Bacterial Infection through the 67LR/p38/JNK Signaling Pathway.
Topics: Animals; Bacterial Infections; Catechin; Macrophages; MAP Kinase Signaling System; Mice; p38 Mitogen-Activated Protein Kinases; Pharmaceutical Preparations; Receptors, Laminin | 2021 |
Epigallocatechin-3-gallate induces autophagy-related apoptosis associated with LC3B II and Beclin expression of bladder cancer cells.
Topics: Apoptosis; Autophagy; Beclin-1; Catechin; Cell Line, Tumor; Humans; Microtubule-Associated Proteins; Phosphatidylinositol 3-Kinases; Urinary Bladder Neoplasms | 2021 |
Green Tea-Derived Epigallocatechin Gallate Inhibits Acid Production and Promotes the Aggregation of Streptococcus mutans and Non-Mutans Streptococci.
Topics: Biofilms; Catechin; Dental Caries; Humans; Streptococcus mutans; Tea | 2021 |
Epigallocatechin-3-Gallate Provides Protection Against Alzheimer's Disease-Induced Learning and Memory Impairments in Rats.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Antioxidants; Aspartic Acid Endopeptidases; Catechin; Cognition Disorders; Dose-Response Relationship, Drug; Hippocampus; Male; Maze Learning; Memory Disorders; Neuroprotective Agents; Peptide Fragments; Rats; Rats, Sprague-Dawley; Spatial Memory; tau Proteins | 2021 |
Epigallocatechin Gallate Inhibits the Uridylate-Specific Endoribonuclease Nsp15 and Efficiently Neutralizes the SARS-CoV-2 Strain.
Topics: Antiviral Agents; Catechin; COVID-19; Endoribonucleases; Humans; Pandemics; SARS-CoV-2; Uridylate-Specific Endoribonucleases; Viral Nonstructural Proteins | 2021 |
EGCG decreases myocardial infarction in both I/R and MIRI rats through reducing intracellular Ca2+ and increasing TnT levels in cardiomyocytes.
Topics: Animals; Apoptosis; Calcium; Catechin; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Troponin T | 2021 |
Epigallocatechin-3-gallate attenuates acute pancreatitis induced lung injury by targeting mitochondrial reactive oxygen species triggered NLRP3 inflammasome activation.
Topics: Acute Lung Injury; Animals; Antioxidants; Catechin; Disease Models, Animal; DNA, Mitochondrial; Inflammasomes; Inflammation; Lung; Lung Injury; Male; Mice; Mitochondria; NLR Family, Pyrin Domain-Containing 3 Protein; Pancreatitis; Reactive Oxygen Species; Tea | 2021 |
Hawthorn polyphenols, D-chiro-inositol, and epigallocatechin gallate exert a synergistic hypoglycemic effect.
Topics: Animals; Catechin; Crataegus; Diabetes Mellitus, Type 2; Glycogen Synthase Kinase 3; Hypoglycemic Agents; Inositol; Mice; Phosphatidylinositol 3-Kinases; Polyphenols | 2021 |
Inhibition of α-glucosidases by tea polyphenols in rat intestinal extract and Caco-2 cells grown on Transwell.
Topics: Acarbose; alpha-Glucosidases; Animals; Caco-2 Cells; Catechin; Glucan 1,4-alpha-Glucosidase; Glycoside Hydrolase Inhibitors; Glycoside Hydrolases; Humans; Intestines; Kinetics; Oligo-1,6-Glucosidase; Plant Extracts; Polyphenols; Rats; Sucrase; Tea | 2021 |
Role of epigallocatechin gallate in collagen hydrogels modification based on physicochemical characterization and molecular docking.
Topics: Animals; Catechin; Collagen; Hydrogels; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Molecular Dynamics Simulation; Rheology; Static Electricity; Transition Temperature | 2021 |
Enzymatic and Nonenzymatic Conjugates of Lactoferrin and (-)-Epigallocatechin Gallate: Formation, Structure, Functionality, and Allergenicity.
Topics: Allergens; Catechin; Lactoferrin; Polyphenols | 2021 |
EGCG promotes PRKCA expression to alleviate LPS-induced acute lung injury and inflammatory response.
Topics: Acute Lung Injury; Animals; Catechin; Cytokines; Inflammation; Lipopolysaccharides; Lung; Macrophages; Male; Mice; NF-kappa B; Protein Kinase C-alpha; Signal Transduction | 2021 |
Polyphenol-solubility alters amyloid fibril formation of α-synuclein.
Topics: alpha-Synuclein; Amyloid; Amyloidogenic Proteins; Catechin; Magnetic Resonance Spectroscopy; Polyphenols; Protein Conformation; Solubility | 2021 |
The synergistic protection of EGCG and quercetin against streptozotocin (STZ)-induced NIT-1 pancreatic β cell damage via upregulation of BCL-2 expression by miR-16-5p.
Topics: Animals; Antioxidants; Apoptosis; Catechin; Cell Line; Down-Regulation; Drug Synergism; Insulin-Secreting Cells; Mice; MicroRNAs; Proto-Oncogene Proteins c-bcl-2; Quercetin; Streptozocin; Up-Regulation | 2021 |
Epigallocatechin-3-gallate (EGCG): a potential molecule for the development of therapeutics against emerging SARS-CoV-1, MERS-CoV and SARS-CoV-2 coronaviruses.
Topics: Catechin; COVID-19; Humans; Middle East Respiratory Syndrome Coronavirus; SARS-CoV-2 | 2021 |
Succinylated ferritin as a novel nanocage-like vehicle of polyphenol: Structure, stability, and absorption analysis.
Topics: Caco-2 Cells; Catechin; Drug Carriers; Drug Stability; Ferritins; Humans; Hydrophobic and Hydrophilic Interactions; Nanostructures; Polyphenols | 2021 |
Targeting Lactate Dehydrogenase A with Catechin Resensitizes SNU620/5FU Gastric Cancer Cells to 5-Fluorouracil.
Topics: Apoptosis; Catechin; Cell Line, Tumor; Drug Resistance, Neoplasm; Fluorouracil; Glycolysis; Humans; Lactate Dehydrogenase 5; Reactive Oxygen Species; Stomach; Stomach Neoplasms | 2021 |
EGCG-Mediated Potential Inhibition of Biofilm Development and Quorum Sensing in
Topics: Acyl-Butyrolactones; Animals; Biofilms; Caenorhabditis elegans; Catechin; Gene Expression Regulation, Bacterial; Glycolipids; Microbial Sensitivity Tests; Movement; Peptide Hydrolases; Pseudomonas aeruginosa; Pyocyanine; Quorum Sensing | 2021 |
Molecular Capture and Conformational Change of Diketopiperazines Containing Proline Residues by Epigallocatechin-3-O-gallate in Water.
Topics: Catechin; Crystallography, X-Ray; Diketopiperazines; Models, Molecular; Molecular Structure; Proline; Stereoisomerism; Water | 2021 |
Epigallocatechin gallate/L-ascorbic acid-loaded poly-γ-glutamate microneedles with antioxidant, anti-inflammatory, and immunomodulatory effects for the treatment of atopic dermatitis.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Catechin; Cytokines; Dermatitis, Atopic; Humans; Immunity; Mice; Polyglutamic Acid; Skin | 2021 |
Effects of different dietary polyphenols on conformational changes and functional properties of protein-polyphenol covalent complexes.
Topics: Antioxidants; Apigenin; Catechin; Electrophoresis, Polyacrylamide Gel; Flavanones; Free Radicals; Functional Food; Hydrophobic and Hydrophilic Interactions; Particle Size; Polyphenols; Quercetin; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Whey Proteins | 2021 |
Glucosyl-hesperidin enhances the cyclic guanosine monophosphate-inducing effect of a green tea polyphenol EGCG.
Topics: Animals; Catechin; Guanosine Monophosphate; Hesperidin; Polyphenols; Tea | 2021 |
Dissipation of Chlorpyrifos in Bottled Tea Beverages and the Effects of (-)-Epigallocatechin-3-Gallate.
Topics: Beverages; Catechin; Chlorpyrifos; Hydrogen Peroxide; Tea | 2021 |
Suppressing effects of green tea extract and Epigallocatechin-3-gallate (EGCG) on TGF-β- induced Epithelial-to-mesenchymal transition via ROS/Smad signaling in human cervical cancer cells.
Topics: Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Plant Extracts; Reactive Oxygen Species; Signal Transduction; Smad Proteins; Tea; Transforming Growth Factor beta; Uterine Cervical Neoplasms | 2021 |
EGCG synergizes the therapeutic effect of irinotecan through enhanced DNA damage in human colorectal cancer cells.
Topics: Antioxidants; Autophagy; Catechin; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; DNA Damage; Drug Synergism; Drug Therapy, Combination; Humans; Irinotecan; Topoisomerase I Inhibitors | 2021 |
Identification of a novel endogenous long non-coding RNA that inhibits selenoprotein P translation.
Topics: Catechin; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation; Humans; Protein Biosynthesis; RNA-Binding Proteins; RNA, Long Noncoding; RNA, Messenger; Selenoprotein P | 2021 |
Epigallocatechin gallate regulates inflammatory responses and new bone formation through Wnt/β-Catenin/COX-2 pathway in spondyloarthritis.
Topics: Administration, Oral; Animals; Arthritis, Experimental; beta Catenin; Catechin; Cyclooxygenase 2; Drug Evaluation, Preclinical; Humans; Male; Mice; Osteogenesis; Spondylarthritis; Wnt Signaling Pathway | 2021 |
An Epigallocatechin-3-gallate Formulation Developed for Endodontic Use: A Physicochemical and Biological Evaluation.
Topics: Animals; Calcium Hydroxide; Catechin; Dogs; Mice; Periapical Periodontitis; Periapical Tissue | 2021 |
Epigallocatechin gallate and Lactobacillus plantarum culture supernatants exert bactericidal activity and reduce biofilm formation in Clostridium perfringens.
Topics: Biofilms; Catechin; Clostridium perfringens; Culture Media, Conditioned; Gene Expression Regulation, Bacterial; Lactobacillus plantarum | 2021 |
Epicatechin gallate and epigallocatechin gallate are potent inhibitors of human arylacetamide deacetylase.
Topics: Carboxylic Ester Hydrolases; Catechin; Curcumin; Enzyme Inhibitors; Flavonoids; Humans; Hydrolysis; Inactivation, Metabolic; Microsomes, Liver; Quercetin | 2021 |
Staphylococcus aureus membrane-damaging activities of four phenolics.
Topics: Anti-Bacterial Agents; Catechin; Cell Membrane; Coumarins; Naphthoquinones; Parabens; Phenols; Staphylococcus aureus | 2021 |
Epigallocatechin-3-gallate plays more predominant roles than caffeine for inducing actin-crosslinking, ubiquitin/proteasome activity and glycolysis, and suppressing angiogenesis features of human endothelial cells.
Topics: Angiogenesis Inhibitors; Caffeine; Catechin; Cell Line, Tumor; Cell Proliferation; Coffee; Cross-Linking Reagents; Endothelial Cells; Endothelium, Vascular; Glycolysis; Humans; Matrix Metalloproteinase 2; Neovascularization, Pathologic; Proteasome Endopeptidase Complex; Tea; Ubiquitin; Ubiquitination | 2021 |
Co-encapsulation of (-)-epigallocatechin-3-gallate and piceatannol/oxyresveratrol in β-lactoglobulin: effect of ligand-protein binding on the antioxidant activity, stability, solubility and cytotoxicity.
Topics: Antioxidants; Catechin; In Vitro Techniques; Lactoglobulins; Molecular Docking Simulation; Plant Extracts; Protein Binding; Spectrometry, Fluorescence; Stilbenes | 2021 |
Effect of Water Hardness on Catechin and Caffeine Content in Green Tea Infusions.
Topics: Caffeine; Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Hardness; Minerals; Plant Extracts; Tea; Water | 2021 |
Epigallocatechin-3-Gallate Modulates Postoperative Pain by Regulating Biochemical and Molecular Pathways.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; beta Catenin; Catechin; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Frizzled Receptors; Male; NF-kappa B; Nitric Oxide Synthase Type II; Pain, Postoperative; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Wnt Proteins; Wnt Signaling Pathway | 2021 |
Significant Inactivation of SARS-CoV-2 In Vitro by a Green Tea Catechin, a Catechin-Derivative, and Black Tea Galloylated Theaflavins.
Topics: Angiotensin-Converting Enzyme 2; Animals; Antiviral Agents; Biflavonoids; Catechin; Cell Survival; Chlorocebus aethiops; COVID-19; Gallic Acid; Humans; Protein Interaction Maps; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Tea; Vero Cells; Virus Replication | 2021 |
Promotion Effect of EGCG on the Raised Expression of IL-23 through the Signaling of STAT3-BATF2-c-JUN/ATF2.
Topics: Activating Transcription Factor 2; Animals; Basic-Leucine Zipper Transcription Factors; Catechin; Interferon Regulatory Factors; Interleukin-23; Mice; Mice, Inbred BALB C; NF-kappa B; Proto-Oncogene Proteins c-jun; STAT3 Transcription Factor | 2021 |
Physiological Dose of EGCG Attenuates the Health Defects of High Dose by Regulating MEMO-1 in
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Catechin; Intracellular Signaling Peptides and Proteins | 2021 |
Fabrication of Zein-Lecithin-EGCG complex nanoparticles: Characterization, controlled release in simulated gastrointestinal digestion.
Topics: Catechin; Delayed-Action Preparations; Digestion; Lecithins; Nanoparticles; Particle Size; Zein | 2021 |
Structural and mechanistic insights into amyloid-β and α-synuclein fibril formation and polyphenol inhibitor efficacy in phospholipid bilayers.
Topics: alpha-Synuclein; Amyloid; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloidogenic Proteins; Catechin; Humans; Lipid Bilayers; Membrane Lipids; Parkinson Disease; Phospholipids; Polyphenols | 2022 |
Potential effect of EGCG on the anti-tumor efficacy of metformin in melanoma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Cell Survival; Cytokines; Cytoplasm; Inflammation; Melanoma; Melanoma, Experimental; Metformin; Mice; NF-kappa B p50 Subunit; Oxidative Stress; Phosphorylation; Skin Neoplasms; Spectrum Analysis, Raman; STAT3 Transcription Factor | 2021 |
Tissue engineered artificial liver model based on viscoelastic hyaluronan-collagen hydrogel and the effect of EGCG intervention on ALD.
Topics: Animals; Catechin; Collagen; Hyaluronic Acid; Hydrogels; Liver; Liver Diseases, Alcoholic; Liver, Artificial; Mice | 2021 |
Novel Perbutyrylated Glucose Derivatives of (-)-Epigallocatechin-3-Gallate Inhibit Cancer Cells Proliferation by Decreasing Phosphorylation of the EGFR: Synthesis, Cytotoxicity, and Molecular Docking.
Topics: A549 Cells; Antineoplastic Agents; Catechin; Cell Proliferation; Cytotoxins; ErbB Receptors; Glucose; HL-60 Cells; Humans; MCF-7 Cells; Molecular Docking Simulation; Neoplasm Proteins; Neoplasms; Phosphorylation | 2021 |
Oral epigallocatechin gallate reduces intestinal nadolol absorption via modulation of Oatp1a5 and Oct1 transcriptional levels in spontaneously hypertensive rats.
Topics: Animals; Catechin; Catecholamine Plasma Membrane Transport Proteins; Intestinal Absorption; Male; Nadolol; Organic Anion Transporters, Sodium-Independent; Rats; Rats, Inbred SHR | 2021 |
Application of a Reactive Oxygen Species-Responsive Drug-Eluting Coating for Surface Modification of Vascular Stents.
Topics: Animals; Catechin; Cell Movement; Cell Proliferation; Cells, Cultured; Coated Materials, Biocompatible; Coronary Restenosis; Cystamine; Drug Liberation; Drug-Eluting Stents; Endothelial Cells; Macrophages; Male; Myocytes, Smooth Muscle; Neovascularization, Physiologic; Oxidation-Reduction; Quinolines; Rabbits; Rats, Sprague-Dawley; Reactive Oxygen Species; Stainless Steel | 2021 |
Stability and antioxidant capacity of epigallocatechin gallate in Dulbecco's modified eagle medium.
Topics: Antioxidants; Catechin; Chromatography, Liquid; Oxidation-Reduction; Tandem Mass Spectrometry | 2022 |
Epigallocatechin-3-gallate stimulates StAR expression and progesterone production in human granulosa cells through the 67-kDa laminin receptor-mediated CREB signaling pathway.
Topics: Catechin; Female; Granulosa Cells; Humans; Phosphoproteins; Progesterone; Receptors, Laminin; Signal Transduction | 2022 |
[Constructing Brain Aβ-Targeting Nanoparticles Loaded with EGCG for Treating Alzheimer's Disease in Mice].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Catechin; Disease Models, Animal; Hippocampus; Mice; Mice, Inbred ICR; Nanoparticles; Oligopeptides | 2021 |
Epigallocatechin Gallate Alleviates Down-Regulation of Thioredoxin in Ischemic Brain Damage and Glutamate-Exposed Neuron.
Topics: Animals; Antioxidants; Brain Ischemia; Catechin; Cell Line, Transformed; Down-Regulation; Glutamic Acid; Male; Mice; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Thioredoxins | 2021 |
Quenching effects of (-)-Epigallocatechin gallate for singlet oxygen production and its protection against oxidative damage induced by Ce6-mediated photodynamic therapy in vitro.
Topics: Animals; Catechin; Mice; Oxidative Stress; Photochemotherapy; Photosensitizing Agents; Singlet Oxygen | 2021 |
A Study of the Interaction, Morphology, and Structure in Trypsin-Epigallocatechin-3-Gallate Complexes.
Topics: Catechin; Humans; Microscopy, Atomic Force; Models, Molecular; Protein Aggregates; Protein Conformation; Solutions; Spectrometry, Fluorescence; Trypsin | 2021 |
Synergistic antimicrobial activities of epigallocatechin gallate, myricetin, daidzein, gallic acid, epicatechin, 3-hydroxy-6-methoxyflavone and genistein combined with antibiotics against ESKAPE pathogens.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Catechin; Drug Resistance, Multiple, Bacterial; Drug Synergism; Flavones; Flavonoids; Gallic Acid; Genistein; Isoflavones; Microbial Sensitivity Tests | 2022 |
Epigallocatechin-3 gallate regulates macrophage subtypes and immunometabolism to ameliorate experimental autoimmune encephalomyelitis.
Topics: Animals; Catechin; Cell Differentiation; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Glycolysis; Humans; Macrophages; Male; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Neuroprotective Agents; NF-kappa B; Signal Transduction; Tea; Th1 Cells; Th2 Cells | 2021 |
Epigallocatechin-3-gallate improves chronic alcohol-induced cognitive dysfunction in rats by interfering with neuro-inflammatory, cell death and oxido-nitrosative cascade.
Topics: Acetylcholinesterase; Animals; Catechin; Cell Death; Cognitive Dysfunction; Ethanol; Hippocampus; Male; Maze Learning; Oxidative Stress; Rats; Rats, Wistar | 2021 |
EGCG as an anti-SARS-CoV-2 agent: Preventive versus therapeutic potential against original and mutant virus.
Topics: Animals; Antiviral Agents; Catechin; Chlorocebus aethiops; COVID-19 Drug Treatment; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutation; SARS-CoV-2; Vero Cells; Viral Proteins; Virus Internalization | 2021 |
Cytocompatibility and Synergy of EGCG and Cationic Peptides Against Bacteria Related to Endodontic Infections, in Planktonic and Biofilm Conditions.
Topics: Actinomyces; Anti-Infective Agents; Biofilms; Catechin; Enterococcus faecalis; Fusobacterium nucleatum; Peptides; Streptococcus mutans | 2021 |
Identification of natural compounds as SARS-CoV-2 entry inhibitors by molecular docking-based virtual screening with bio-layer interferometry.
Topics: Angiotensin-Converting Enzyme 2; Animals; Antiviral Agents; Binding, Competitive; Biological Products; Catechin; Cell Membrane; Chalcones; Chlorogenic Acid; COVID-19 Drug Treatment; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Ginsenosides; Humans; Interferometry; Mice, Inbred C57BL; Molecular Dynamics Simulation; Phenols; Protein Binding; SARS-CoV-2; Spike Glycoprotein, Coronavirus | 2021 |
EGCG inhibits growth of tumoral lesions on lip and tongue of K-Ras transgenic mice through the Notch pathway.
Topics: Animals; Antineoplastic Agents; Apoptosis; Camellia sinensis; Catechin; Cell Line, Tumor; Cell Proliferation; Humans; Lip Neoplasms; Mice; Mice, Transgenic; Plant Extracts; Proto-Oncogene Proteins p21(ras); Receptors, Notch; Signal Transduction; Tongue Neoplasms; Xenograft Model Antitumor Assays | 2022 |
Reduction of 3-Deoxyglucosone by Epigallocatechin Gallate Results Partially from an Addition Reaction: The Possible Mechanism of Decreased 5-Hydroxymethylfurfural in Epigallocatechin Gallate-Treated Black Garlic.
Topics: Catechin; Deoxyglucose; Dose-Response Relationship, Drug; Furaldehyde; Garlic | 2021 |
Super-Resolution Microscopy Revealed the Lysosomal Expansion During Epigallocatechin Gallate-Mediated Apoptosis.
Topics: Apoptosis; Catechin; Lysosomes; Microscopy; Reactive Oxygen Species | 2021 |
Epigallocatechin gallate inhibits release of extracellular vesicles from platelets without inhibiting phosphatidylserine exposure.
Topics: Annexin A5; Blood Coagulation; Blood Platelets; Catechin; Extracellular Vesicles; Humans; Phosphatidylserines | 2021 |
Enhancement of Annexin V in response to combination of epigallocatechin gallate and quercetin as a potent arrest the cell cycle of colorectal cancer.
Topics: Annexin A5; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Humans; Quercetin | 2021 |
Enhanced
Topics: Catechin; Lactobacillus acidophilus; Probiotics; Whey Proteins | 2021 |
(-)-Epigallocatechin-3-gallate (EGCG) prevents aminoglycosides-induced ototoxicity via anti-oxidative and anti-apoptotic pathways.
Topics: Aminoglycosides; Animals; Apoptosis; Catechin; Humans; Molecular Docking Simulation; Ototoxicity; Pharmaceutical Preparations; Reactive Oxygen Species; Zebrafish | 2021 |
De Novo Missense Mutations in
Topics: Adenosine Triphosphatases; Adult; Calcium; Cardiomyopathies; Catechin; Humans; Infant; Male; Microscopy, Electron, Transmission; Mutation, Missense; Myofibrils; Sarcomeres; Severity of Illness Index; Simendan; Tropomyosin; Troponin I | 2021 |
Epigallocatechin-3-Gallate Allosterically Activates Protein Kinase C-α and Improves the Cognition of Estrogen Deficiency Mice.
Topics: Animals; Catechin; Cognition; Estrogens; Mice; Protein Kinase C-alpha | 2021 |
Complexation of caffeine and theophylline with epigallocatechin gallate in aqueous solution: Nuclear magnetic resonance, molecular docking and thermodynamics studies.
Topics: Caffeine; Catechin; Magnetic Resonance Spectroscopy; Molecular Docking Simulation; Theophylline; Thermodynamics | 2021 |
Effect of epigallocatechin gallate on dental biofilm of Streptococcus mutans: An in vitro study.
Topics: Biofilms; Catechin; Dental Caries; Humans; Streptococcus mutans | 2021 |
Suppression of GOLM1 by EGCG through HGF/HGFR/AKT/GSK-3β/β-catenin/c-Myc signaling pathway inhibits cell migration of MDA-MB-231.
Topics: beta Catenin; Blotting, Western; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Movement; Glycogen Synthase Kinase 3 beta; Hepatocyte Growth Factor; Humans; Membrane Proteins; Proto-Oncogene Proteins c-met; Proto-Oncogene Proteins c-myc; Real-Time Polymerase Chain Reaction; Signal Transduction | 2021 |
Anti-damage effect of theaflavin-3'-gallate from black tea on UVB-irradiated HaCaT cells by photoprotection and maintaining cell homeostasis.
Topics: Antioxidants; Apoptosis; Biflavonoids; Catechin; Cellular Senescence; Gallic Acid; HaCaT Cells; Homeostasis; Humans; Membrane Potential, Mitochondrial; Radiation-Protective Agents; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tea; Ultraviolet Rays | 2021 |
The formation of phycocyanin-EGCG complex for improving the color protection stability exposing to light.
Topics: Catechin; Phycocyanin; Polyphenols | 2022 |
Structural characterization and antioxidant property of enzymatic-transesterification derivatives of (-)-epigallocatechin-3-O-gallate and vinyl laurate.
Topics: Antioxidants; Catechin; Esterification; Laurates; Lipid Peroxidation; Vinyl Compounds | 2021 |
Epigallocatechin gallate (EGCG) attenuates staphylococcal alpha-hemolysin (Hla)-induced NLRP3 inflammasome activation via ROS-MAPK pathways and EGCG-Hla interactions.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Bacterial Proteins; Catechin; Disease Models, Animal; Hemolysin Proteins; Hemolysis; Humans; Inflammasomes; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Staphylococcal Infections; Staphylococcus aureus; THP-1 Cells | 2021 |
Effect of (-)-Epigallocatechin Gallate on Activation of JAK/STAT Signaling Pathway by Staphylococcal Enterotoxin A.
Topics: Animals; Catechin; Cells, Cultured; Disease Models, Animal; Enterotoxins; Gene Expression Regulation, Bacterial; Humans; Janus Kinases; Mice; Signal Transduction; Spleen; Staphylococcus aureus; STAT3 Transcription Factor | 2021 |
Epigallocatechin-3-gallate exhibits anti-inflammatory effects in a human interface dermatitis model-implications for therapy.
Topics: Anti-Inflammatory Agents; Catechin; Dermatitis; Humans; Keratinocytes | 2022 |
Genetic Interpretation of the Impacts of Honokiol and EGCG on Apoptotic and Self-Renewal Pathways in HEp-2 Human Laryngeal CD44
Topics: Apoptosis; Biphenyl Compounds; Catechin; Cell Line, Tumor; Hedgehog Proteins; Humans; Hyaluronan Receptors; Laryngeal Neoplasms; Lignans; Neoplastic Stem Cells; Tumor Suppressor Protein p53 | 2022 |
Prenatal EGCG exposure-induced heart mass reduction in adult male mice and underlying mechanisms.
Topics: Animals; Apoptosis; Caspase 3; Caspase 9; Catechin; Female; Heart; Male; Mice; Mice, Inbred C57BL; Myocardium; Organ Size; Phosphatidylinositol 3-Kinases; Pregnancy; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins c-akt; Signal Transduction; Smad3 Protein; Smad4 Protein | 2021 |
Bilosomes as effective delivery systems to improve the gastrointestinal stability and bioavailability of epigallocatechin gallate (EGCG).
Topics: Biological Availability; Catechin; Liposomes | 2021 |
Epigallocatechin gallate and theaflavins independently alleviate cyclophosphamide-induced ovarian damage by inhibiting the overactivation of primordial follicles and follicular atresia.
Topics: Animals; Biflavonoids; Catechin; Cyclophosphamide; Female; Follicular Atresia; Mice | 2021 |
Potential role of green tea extract and epigallocatechin gallate in preventing bisphenol A-induced metabolic disorders in rats: Biochemical and molecular evidence.
Topics: Animals; Antioxidants; Benzhydryl Compounds; Catechin; Metabolic Diseases; Phenols; Plant Extracts; Rats; Tea | 2021 |
Epigallocatechin gallate (EGCG) attenuates myocardial hypertrophy and fibrosis induced by transverse aortic constriction via inhibiting the Akt/mTOR pathway.
Topics: Animals; Cardiomegaly; Cardiotonic Agents; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases | 2021 |
Green tea catechins EGCG and ECG enhance the fitness and lifespan of
Topics: Animals; Caenorhabditis elegans; Catechin; Electron Transport Complex I; Longevity; Mitochondria; Stress, Physiological; Tea | 2021 |
Plasma-Induced Oxidation Products of (-)-Epigallocatechin Gallate with Digestive Enzymes Inhibitory Effects.
Topics: alpha-Amylases; alpha-Glucosidases; Animals; Camellia sinensis; Catechin; Glycoside Hydrolase Inhibitors; Molecular Structure; Oxidation-Reduction; Pancreas; Plant Leaves; Plasma Gases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Swine; Water | 2021 |
Development of HPLC Method for Catechins and Related Compounds Determination and Standardization in Miang (Traditional Lanna Fermented Tea Leaf in Northern Thailand).
Topics: Caffeine; Camellia sinensis; Catechin; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Gallic Acid; Plant Extracts; Plant Leaves; Reference Standards; Thailand; Validation Studies as Topic | 2021 |
Repeated exposure to epigallocatechin gallate solution or water alters bitterness intensity and salivary protein profile.
Topics: Catechin; Humans; Saliva; Salivary Proteins and Peptides; Taste; Water | 2021 |
New degradation mechanism of black tea pigment theaflavin involving condensation with epigallocatechin-3-O-gallate.
Topics: Biflavonoids; Catechin; Tea | 2022 |
Vitamin D and green tea extracts for the treatment of uterine fibroids in late reproductive life: a pilot, prospective, daily-diary based study.
Topics: Adult; Catechin; Female; Humans; Leiomyoma; Pilot Projects; Plant Extracts; Premenopause; Prospective Studies; Tea; Uterine Neoplasms; Vitamin D | 2022 |
Probing the conjugation of epigallocatechin gallate with β-lactoglobulin and its
Topics: Allergens; Animals; Catechin; Desensitization, Immunologic; Female; Gastrointestinal Microbiome; Immune Tolerance; Immunoglobulin E; Lactoglobulins; Mice; Mice, Inbred BALB C | 2021 |
Light control of catechin accumulation is mediated by photosynthetic capacity in tea plant (Camellia sinensis).
Topics: Camellia sinensis; Catechin; Gene Expression Regulation, Plant; Light; Photosynthesis; Plant Proteins; Seedlings; Up-Regulation | 2021 |
Effect of EGCG on bronchial epithelial cell premalignant lesions induced by cigarette smoke and on its CYP1A1 expression.
Topics: Animals; Bronchi; Catechin; Cell Line; Cell Transformation, Neoplastic; Cytochrome P-450 CYP1A1; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MicroRNAs; Rats; Rats, Sprague-Dawley; Signal Transduction; Smoke; Smoking | 2021 |
Molecular Mechanism of Food-Derived Polyphenols on PD-L1 Dimerization: A Molecular Dynamics Simulation Study.
Topics: B7-H1 Antigen; Binding Sites; Catechin; Dimerization; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Polyphenols; Protein Binding; Protein Structure, Secondary; Resveratrol; Thermodynamics | 2021 |
Epigallocatechin-3-gallate protects cardiomyocytes from hypoxia-reoxygenation damage via raising autophagy related 4C expression.
Topics: Apoptosis; Autophagy-Related Proteins; Catechin; Cell Hypoxia; Cell Line; Cysteine Endopeptidases; Gene Expression Regulation, Enzymologic; Humans; Myocardial Reperfusion Injury; Myocytes, Cardiac | 2021 |
Co-encapsulation of (-)-epigallocatechin-3-gallate and quercetin in double emulsion hydrogel beads: Microstructures, functional properties, and digestion behaviors.
Topics: Catechin; Digestion; Emulsions; Hydrogels; Quercetin | 2022 |
(+)-Catechin, epicatechin and epigallocatechin gallate are important inducible defensive compounds against Ectropis grisescens in tea plants.
Topics: Animals; Antibiosis; Camellia sinensis; Catechin; Herbivory; Larva; Moths | 2022 |
(-)-Epigallocatechin-3-gallate mitigates cyclophosphamide-induced intestinal injury by modulating the tight junctions, inflammation and dysbiosis in mice.
Topics: Animals; Catechin; Cyclophosphamide; Dysbiosis; Gastrointestinal Microbiome; Inflammation; Intestinal Diseases; Male; Mice; Mice, Inbred ICR; Tight Junctions | 2021 |
Tuning curvature and phase behavior of monoolein bilayers by epigallocatechin-3-gallate: Structural insight and cytotoxicity.
Topics: Catechin; Glycerides; Tea | 2022 |
EGCG protects against myocardial I/RI by regulating lncRNA Gm4419-mediated epigenetic silencing of the DUSP5/ERK1/2 axis.
Topics: Animals; Autophagy; Catechin; Cells, Cultured; Disease Models, Animal; Dual-Specificity Phosphatases; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Silencing; Hydrogen Peroxide; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Reperfusion Injury; Myocytes, Cardiac; RNA, Long Noncoding; Signal Transduction | 2021 |
[Effects of (+)-catechin and epigallocatechin gallate on alcoholic fatty liver in mice models].
Topics: Animals; Catechin; Fatty Liver, Alcoholic; Liver; Mice; Non-alcoholic Fatty Liver Disease | 2021 |
Epigallocatechin 3-gallate improves the quality of bull semen cryopreservation.
Topics: Animals; Antioxidants; Catechin; Cattle; Cryopreservation; Cryoprotective Agents; Male; Semen; Semen Analysis; Semen Preservation; Sperm Motility; Spermatozoa | 2022 |
Mitophagy enhancers against phosphorylated Tau-induced mitochondrial and synaptic toxicities in Alzheimer disease.
Topics: Alzheimer Disease; Animals; Catechin; Cell Line; Coumarins; DNA-Binding Proteins; High Mobility Group Proteins; Hippocampus; Mice; Mitochondria; Mitochondrial Dynamics; Mitophagy; Neurons; NF-E2-Related Factor 2; Nuclear Respiratory Factor 1; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; Synapses; Synaptophysin; tau Proteins | 2021 |
Effect of Epigallocatechin-3-Gallate on EGFR Signaling and Migration in Non-Small Cell Lung Cancer.
Topics: A549 Cells; Carcinoma, Non-Small-Cell Lung; Catechin; ErbB Receptors; Humans; Lung Neoplasms; Neoplasm Proteins; Signal Transduction | 2021 |
Mitochondria-Mediated Moderation of Apoptosis by EGCG in Cytotoxic Neuronal Cells Induced by Lead (Pb) and Amyloid Peptides.
Topics: Antioxidants; Apoptosis; Catechin; Cytochromes c; Humans; Lead; Mitochondria; Neuroblastoma; Oxidants; Oxidative Stress; Peptides | 2022 |
Effects of epigallocatechin gallate on the stability, dissolution and toxicology of ZnO nanoparticles.
Topics: Caco-2 Cells; Catechin; Humans; Metal Nanoparticles; Solubility; Zinc Oxide | 2022 |
Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Camellia sinensis; Catechin; Drug Interactions; Glucose; Glutamates; Glycogen; Glycogen Synthase; Insulin; Lipid Metabolism; Liver; Male; Muscles; Phosphorylation; Plant Extracts; Proteins; Rats, Sprague-Dawley; Receptor, Insulin; Ribosomal Protein S6 Kinases; Tea; TOR Serine-Threonine Kinases | 2021 |
EGCG prevents pressure overload‑induced myocardial remodeling by downregulating overexpression of HDAC5 in mice.
Topics: Acetylation; Animals; Atrial Natriuretic Factor; Atrial Remodeling; Catechin; Constriction; Disease Models, Animal; Electrocardiography; Heart Failure; Histone Deacetylases; Histones; Lysine; Male; MEF2 Transcription Factors; Natriuretic Peptide, Brain; Survival Rate; Ventricular Remodeling | 2022 |
Sodium alginate/soybean protein-epigallocatechin-3-gallate conjugate hydrogel beads: evaluation of structural, physical, and functional properties.
Topics: Alginates; Antioxidants; Catechin; Drug Delivery Systems; Humans; Hydrogels; Soybean Proteins; Structure-Activity Relationship | 2021 |
Design and construction of IR780- and EGCG-based and mitochondrial targeting nanoparticles and their application in tumor chemo-phototherapy.
Topics: Animals; Antineoplastic Agents; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Design; Drug Screening Assays, Antitumor; Fluorescent Dyes; Humans; Indoles; Iodides; Materials Testing; Mitochondria; Molecular Structure; Nanoparticles; Neoplasms, Experimental; Photosensitizing Agents; Photothermal Therapy; Zebrafish | 2021 |
Methylated (-)-epigallocatechin 3-O-gallate potentiates the effect of split vaccine accompanied with upregulation of Toll-like receptor 5.
Topics: Animals; Catechin; Drug Administration Schedule; Drug Synergism; Female; Hemagglutination; Immunity, Humoral; Influenza Vaccines; Japan; Macrophages; Methylation; Mice; Mice, Inbred BALB C; Plant Extracts; Spleen; Tea; Toll-Like Receptor 5; Up-Regulation | 2021 |
In vitro co-metabolism of epigallocatechin-3-gallate (EGCG) by the mucin-degrading bacterium Akkermansia muciniphila.
Topics: Akkermansia; Catechin; Glucose; In Vitro Techniques; Metabolome; Mucins | 2021 |
EGCG-gelatin biofilm improved the protein degradation, flavor and micromolecule metabolites of tilapia fillets during chilled storage.
Topics: Animals; Biofilms; Catechin; Gelatin; Proteolysis; Seafood; Tilapia | 2022 |
Cytotoxic Aβ Protofilaments Are Generated in the Process of Aβ Fibril Disaggregation.
Topics: Amyloid; Amyloid beta-Peptides; Antioxidants; Catechin; Dopamine; Dopamine Agents; Humans; Neuroblastoma; Tumor Cells, Cultured | 2021 |
MT1-MMP Cooperates with TGF-β Receptor-Mediated Signaling to Trigger SNAIL and Induce Epithelial-to-Mesenchymal-like Transition in U87 Glioblastoma Cells.
Topics: Brain Neoplasms; Catechin; Cell Line, Tumor; Concanavalin A; Epithelial-Mesenchymal Transition; Fibronectins; Glioblastoma; Humans; Matrix Metalloproteinase 14; Piperidines; Pyrazoles; Pyrimidines; Quinolines; Receptors, Transforming Growth Factor beta; Signal Transduction; Snail Family Transcription Factors; STAT3 Transcription Factor; Transforming Growth Factor beta1; Tyrphostins | 2021 |
Fabrication of chitosan-coated epigallocatechin-3-gallate (EGCG)-hordein nanoparticles and their transcellular permeability in Caco-2/HT29 cocultures.
Topics: Biological Transport; Caco-2 Cells; Catechin; Cell Line; Cells, Cultured; Chitosan; Drug Carriers; Glutens; Humans; Nanoparticles; Particle Size; Permeability; Spectrum Analysis | 2022 |
Epigallocatechin-3-gallate inhibits replication of white spot syndrome virus in the freshwater crayfish Procambarus clarkii.
Topics: Animals; Astacoidea; Catechin; Fresh Water; Virus Replication; White spot syndrome virus 1 | 2022 |
Interaction between β-lactoglobulin and EGCG under high-pressure by molecular dynamics simulation.
Topics: Catechin; Humans; Lactoglobulins; Molecular Dynamics Simulation; Pressure; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand | 2021 |
Multi-ligand modified PC@DOX-PA/EGCG micelles effectively inhibit the growth of ER
Topics: Animals; Antineoplastic Agents; Apoptosis; Biflavonoids; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Carriers; Drug Liberation; Humans; Ligands; Mice, Inbred BALB C; Micelles; Phosphatidylcholines; Proanthocyanidins | 2022 |
(-)-Epigallocatechin-3-Gallate Diminishes Intra-and Extracellular Amyloid-Induced Cytotoxic Effects on Cholinergic-like Neurons from Familial Alzheimer's Disease PSEN1 E280A.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Catechin; Cells, Cultured; Cholinergic Neurons; Female; Gene Regulatory Networks; Humans; Hydrogen Peroxide; Microscopy, Fluorescence; Models, Biological; Mutation; Presenilin-1; Protein Aggregates | 2021 |
Epigallocatechin Gallate (EGCG), a Green Tea Polyphenol, Reduces Coronavirus Replication in a Mouse Model.
Topics: Animals; Antiviral Agents; Catechin; Cell Line; Coronavirus Infections; Coronavirus OC43, Human; Disease Models, Animal; Humans; Mice; Polyphenols; Tea; Virus Replication | 2021 |
Epigallocatechin gallate facilitates extracellular elastin fiber formation in induced pluripotent stem cell derived vascular smooth muscle cells for tissue engineering.
Topics: Catechin; Elastin; Humans; Induced Pluripotent Stem Cells; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Reproducibility of Results; Tissue Engineering | 2022 |
Effects of the psychoactive compounds in green tea on risky decision-making.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Caffeine; Catechin; Cognition; Compulsive Behavior; Decision Making; Dose-Response Relationship, Drug; Drug Monitoring; Locomotion; Models, Animal; Psychotropic Drugs; Rats; Risk-Taking; Tea | 2022 |
Does ( -)-epigallocatechin-3-gallate protect the neurotoxicity induced by bisphenol A in vivo?
Topics: Animals; Antioxidants; Benzhydryl Compounds; Catechin; Neurotoxicity Syndromes; Oxidative Stress; Phenols; Rats | 2022 |
Excess serum Na level in rats administered with high doses of (-)-epigallocatechin gallate-casein nanoparticles prepared with sodium caseinate.
Topics: Animals; Caseins; Catechin; Drug Carriers; Models, Animal; Nanoparticles; Rats; Rats, Sprague-Dawley; Sodium | 2022 |
Epigallocatechin‑3‑gallate hinders metabolic coupling to suppress colorectal cancer malignancy through targeting aerobic glycolysis in cancer‑associated fibroblasts.
Topics: Cancer-Associated Fibroblasts; Catechin; Colorectal Neoplasms; Humans; Neoplasms; Oxidative Coupling; Warburg Effect, Oncologic | 2022 |
Epigallocatechin gallate stimulated histamine production and downregulated histamine H1 receptor in oral cancer cell lines expressing histidine decarboxylase.
Topics: Catechin; Cell Line; Histamine; Histidine Decarboxylase; Humans; Mouth Neoplasms; Receptors, Cell Surface; Receptors, Histamine H1 | 2022 |
Study on the stability and oral bioavailability of curcumin loaded (-)-epigallocatechin-3-gallate/poly(N-vinylpyrrolidone) nanoparticles based on hydrogen bonding-driven self-assembly.
Topics: Biological Availability; Caco-2 Cells; Catechin; Curcumin; Drug Carriers; Humans; Hydrogen Bonding; Nanoparticles; Particle Size; Pyrrolidinones | 2022 |
The Invasive Potential of Hepatoma Cells Induced by Radiotherapy is Related to the Activation of Hepatic Stellate Cells and Could be Inhibited by EGCG Through the TLR4 Signaling Pathway.
Topics: Animals; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Hepatic Stellate Cells; Interleukin-6; Liver Neoplasms; Mice; Signal Transduction; Toll-Like Receptor 4; Tumor Microenvironment | 2022 |
Gallic Acid Derivatives Propyl Gallate and Epigallocatechin Gallate Reduce rRNA Transcription via Induction of KDM2A Activation.
Topics: Catechin; Cell Line, Tumor; F-Box Proteins; Gallic Acid; Humans; Jumonji Domain-Containing Histone Demethylases; Propyl Gallate | 2021 |
Treg/Th17 Ratio Regulation May Play an Important Role in Epigallocatechin-3-Gallate-Mediated Attenuation of Increased Afterload-Induced Cardiac Hypertrophy.
Topics: Animals; Cardiomegaly; Catechin; Disease Models, Animal; Eosine Yellowish-(YS); Hematoxylin; Male; Mice; Mice, Inbred C57BL; T-Lymphocytes, Regulatory; Th17 Cells; Wheat Germ Agglutinins | 2022 |
Preparation, characterization and releasing property of antibacterial nano-capsules composed of ε-PL-EGCG and sodium alginate-chitosan.
Topics: Alginates; Anti-Bacterial Agents; Catechin; Chitosan; Nanoparticles; Spectroscopy, Fourier Transform Infrared | 2022 |
Compound screening identified gossypetin and isoquercitrin as novel inhibitors for amyloid fibril formations of Vλ6 proteins associated with AL amyloidosis.
Topics: Amyloid; Antioxidants; Catechin; Dose-Response Relationship, Drug; Flavonoids; Humans; Immunoglobulin lambda-Chains; Immunoglobulin Light-chain Amyloidosis; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Mutation; Protein Binding; Protein Stability; Quercetin; Time Factors | 2022 |
Nano-enabled delivery of EGCG ameliorates silica-induced pulmonary fibrosis in rats.
Topics: Animals; Catechin; Nanoparticles; Pulmonary Fibrosis; Rats; Silicon Dioxide; Silicosis | 2022 |
RNA-seq profiling of white and brown adipocyte differentiation treated with epigallocatechin gallate.
Topics: Adipocytes, Brown; Adipocytes, White; Anti-Obesity Agents; Catechin; Cell Differentiation; Humans; Obesity; RNA-Seq | 2022 |
EGCG-derived polymeric oxidation products enhance insulin sensitivity in db/db mice.
Topics: Animals; Catechin; Diabetes Mellitus; Insulin Resistance; Kidney; Mice; Oxidation-Reduction | 2022 |
EGCG attenuates the neurotoxicity of methylglyoxal via regulating MAPK and the downstream signaling pathways and inhibiting advanced glycation end products formation.
Topics: Animals; Catechin; Glycation End Products, Advanced; Magnesium Oxide; Mitogen-Activated Protein Kinases; Molecular Docking Simulation; Pyruvaldehyde; Rats; Reactive Oxygen Species; Signal Transduction | 2022 |
Increased dosage and treatment time of Epigallocatechin-3-gallate (EGCG) negatively affects skeletal parameters in normal mice and Down syndrome mouse models.
Topics: Animals; Catechin; Down Syndrome; Drug Administration Schedule; Dyrk Kinases; Female; Male; Mice; Muscle, Skeletal; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases | 2022 |
EGCG Promotes FUS Condensate Formation in a Methylation-Dependent Manner.
Topics: Arginine; Catechin; Glycine; Humans; Methylation; Neurodegenerative Diseases; Proteins; RNA-Binding Protein FUS | 2022 |
The Efficacy Mechanism of Epigallocatechin Gallate against Pre-Eclampsia based on Network Pharmacology and Molecular Docking.
Topics: Catechin; Drugs, Chinese Herbal; Female; Humans; Molecular Docking Simulation; Network Pharmacology; Phosphatidylinositol 3-Kinases; Pre-Eclampsia; Pregnancy | 2022 |
Low dose epigallocatechin-3-gallate revives doxorubicin responsiveness by a redox-sensitive pathway in A549 lung adenocarcinoma cells.
Topics: A549 Cells; Adenocarcinoma of Lung; Catechin; Doxorubicin; Humans; Lung Neoplasms; Oxidation-Reduction | 2022 |
Dual functions of epigallocatechin gallate surface-modified Au nanorods@selenium composites for near-infrared-II light-responsive synergistic antibacterial therapy.
Topics: Animals; Anti-Bacterial Agents; Catechin; Gold; Mice; Nanotubes; Selenium; Staphylococcus aureus | 2022 |
Co-delivery of EGCG and lycopene
Topics: Animals; Catechin; Diet, High-Fat; Emulsions; Lycopene; Rats | 2022 |
Epigallocatechin gallate triggers apoptosis by suppressing de novo lipogenesis in colorectal carcinoma cells.
Topics: Animals; Apoptosis; Catechin; Cell Line, Tumor; Colorectal Neoplasms; Fatty Acids; Humans; Lipogenesis; Mice | 2022 |
An investigation on [5 fluorouracil and epigallocatechin-3-gallate] complex activity on HT-29 cell death and its stability in gastrointestinal fluid.
Topics: Catechin; Cell Survival; Fluorouracil; HT29 Cells; Humans | 2022 |
Structure remodeling of soy protein-derived amyloid fibrils mediated by epigallocatechin-3-gallate.
Topics: Amyloid; Catechin; Humans; Soybean Proteins | 2022 |
Epigallocatechin-3-
Topics: Adult; Aged; Apoptosis; Case-Control Studies; Catechin; Cell Line; Chondrocytes; Dose-Response Relationship, Drug; Extracellular Matrix; Humans; Inflammation; Interleukin-1beta; MicroRNAs; Middle Aged; Osteoarthritis; PTEN Phosphohydrolase; Up-Regulation | 2022 |
[Progress of researches on anti-infective properties of epigallocatechin-3-gallate].
Topics: Antioxidants; Catechin; Humans; Polyphenols; Tea | 2021 |
EGCG Prevents the Onset of an Inflammatory and Cancer-Associated Adipocyte-like Phenotype in Adipose-Derived Mesenchymal Stem/Stromal Cells in Response to the Triple-Negative Breast Cancer Secretome.
Topics: Adipocytes; Catechin; Humans; Mesenchymal Stem Cells; Phenotype; Secretome; Triple Negative Breast Neoplasms; Tumor Microenvironment | 2022 |
Adipose-Derived Stem Cells Preincubated with Green Tea EGCG Enhance Pancreatic Tissue Regeneration in Rats with Type 1 Diabetes through ROS/Sirt1 Signaling Regulation.
Topics: Animals; Catechin; Diabetes Mellitus, Type 1; Humans; Pancreatic Hormones; Rats; Reactive Oxygen Species; Sirtuin 1; Stem Cells; Tea | 2022 |
Epigallocatechin-3-gallate suppresses the growth of human osteosarcoma by inhibiting the Wnt/β-catenin signalling pathway.
Topics: Animals; Apoptosis; beta Catenin; Bone Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Humans; Osteosarcoma; Wnt Signaling Pathway | 2022 |
Inhibition effect of epigallocatechin gallate on the growth and biofilm formation of Vibrio parahaemolyticus.
Topics: Anti-Bacterial Agents; Biofilms; Catechin; Vibrio parahaemolyticus | 2022 |
Epigallocatechin gallate attenuates tumor necrosis factor (TNF)-α-induced inhibition of osteoblastic differentiation by up-regulating lncRNA TUG1 in osteoporosis.
Topics: Animals; Catechin; Cell Differentiation; Mice; Osteoblasts; Osteoporosis; RNA, Long Noncoding; Tumor Necrosis Factor-alpha | 2022 |
Tetranectin targeting by epigallocatechin gallate suppresses colon cancer cell proliferation.
Topics: Catechin; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Humans; Lectins, C-Type; Plasminogen | 2022 |
Preparation of epigallocatechin gallate decorated Au-Ag nano-heterostructures as NIR-sensitive nano-enzymes for the treatment of osteoarthritis through mitochondrial repair and cartilage protection.
Topics: Cartilage, Articular; Catechin; Chondrocytes; Humans; Osteoarthritis | 2022 |
Prooxidant activity-based guideline for a beneficial combination of (-)-epigallocatechin-3-gallate and chlorogenic acid.
Topics: AMP-Activated Protein Kinases; Animals; Catechin; Chlorogenic Acid; Mice; NF-E2-Related Factor 2; Polyphenols; Reactive Oxygen Species | 2022 |
Effect of taxifolin and epigallocatechin-3-gallate on biomineralization potential of stem cells from dental apical papilla.
Topics: Alkaline Phosphatase; Biomineralization; Catechin; Cell Differentiation; Cells, Cultured; Dental Papilla; Quercetin; Stem Cells | 2022 |
Ultra high-Performance Liquid Chromatography (UHPLC) method development and validation for the identification of oxidized product of Epigallocatechin-3-Gallate (EGCG).
Topics: Catechin; Chromatography, High Pressure Liquid; Humans; Hydrogen Peroxide; Oxidation-Reduction | 2023 |
(-)-Epigallocatechin-3-gallate plays an antagonistic role in the antitumor effect of bortezomib in myeloma cells via activating Wnt/β-catenin signaling pathway.
Topics: Apoptosis; Bortezomib; Catechin; Cell Line, Tumor; Cell Proliferation; Humans; Multiple Myeloma; Tea; Wnt Signaling Pathway | 2022 |
Drug Resistance and Epigenetic Modulatory Potential of Epigallocatechin-3-Gallate Against Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Catechin; Drug Resistance; Epigenesis, Genetic; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus | 2022 |
Interactions between the protein-epigallocatechin gallate complex and nanocrystalline cellulose: A systematic study.
Topics: Catechin; Cellulose; Rheology; Suspensions | 2022 |
Painful Diabetic Neuropathy Is Associated with Compromised Microglial IGF-1 Signaling Which Can Be Rescued by Green Tea Polyphenol EGCG in Mice.
Topics: Animals; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Insulin-Like Growth Factor I; Mice; Microglia; Pain; Polyphenols; Tea; Tumor Necrosis Factor-alpha | 2022 |
EGCG Restricts PRRSV Proliferation by Disturbing Lipid Metabolism.
Topics: Animals; Catechin; Cell Line; Cell Proliferation; Female; Lipid Metabolism; Lipids; Porcine Reproductive and Respiratory Syndrome; Porcine respiratory and reproductive syndrome virus; Swine; Tea | 2022 |
Epigallocatechin Gallate Protects against Hypoxia-Induced Inflammation in Microglia via NF-κB Suppression and Nrf-2/HO-1 Activation.
Topics: Catechin; Cyclooxygenase 2; Humans; Hypoxia, Brain; Inflammation; Interleukin-6; Lipopolysaccharides; Microglia; NF-kappa B; Reactive Oxygen Species | 2022 |
Epigallocatechin-3-O-gallate ameliorates oxidative stress-induced chondrocyte dysfunction and exerts chondroprotective effects via the Keap1/Nrf2/ARE signaling pathway.
Topics: Aged; Catechin; Chondrocytes; Humans; Interleukin-1beta; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Oxidative Stress; Signal Transduction | 2022 |
Epigallocatechin-3-gallate exerts cardioprotective effects related to energy metabolism in pressure overload-induced cardiac dysfunction.
Topics: Animals; Cardiomegaly; Catechin; Disease Models, Animal; Energy Metabolism; Heart Failure; Myocardium; Rats; Reproducibility of Results | 2022 |
Antioxidant activity, storage stability and in vitro release of epigallocatechin-3-gallate (EGCG) encapsulated in hordein nanoparticles.
Topics: Antioxidants; Catechin; Glutens; Nanoparticles; Particle Size | 2022 |
EGCG-crosslinked carboxymethyl chitosan-based hydrogels with inherent desired functions for full-thickness skin wound healing.
Topics: Adhesives; Animals; Anti-Bacterial Agents; Antioxidants; Catechin; Chitosan; Escherichia coli; Hydrogels; Mice; Staphylococcus aureus; Vascular Endothelial Growth Factor A; Wound Healing | 2022 |
Engineered EGCG-Containing Biomimetic Nanoassemblies as Effective Delivery Platform for Enhanced Cancer Therapy.
Topics: B7-H1 Antigen; Biomimetics; Catechin; Cell Line, Tumor; Immunologic Factors; Immunotherapy; Neoplasms | 2022 |
EGCG and ECG induce apoptosis and decrease autophagy via the AMPK/mTOR and PI3K/AKT/mTOR pathway in human melanoma cells.
Topics: AMP-Activated Protein Kinases; Apoptosis; Autophagy; Catechin; Electrocardiography; Humans; Melanoma; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases | 2022 |
Preparation and characterization of chitosan films incorporating epigallocatechin gallate: Microstructure, physicochemical, and bioactive properties.
Topics: Anti-Bacterial Agents; Antioxidants; Catechin; Chitosan; Food Packaging; Water | 2022 |
Structure, stability and antioxidant activity of dialdehyde starch grafted with epicatechin, epicatechin gallate, epigallocatechin and epigallocatechin gallate.
Topics: Aldehydes; Antioxidants; Catechin; Flavonoids; Phosphates; Starch; Tea | 2022 |
Inhibition effect of high hydrostatic pressure combined with epigallocatechin gallate treatments on pectin methylesterase in orange juice and model system.
Topics: Carboxylic Ester Hydrolases; Catechin; Citrus sinensis; Hydrostatic Pressure | 2022 |
Epigallocatechin-3-Gallate Ameliorated Iron Accumulation and Apoptosis and Promoted Neuronal Regeneration and Memory/Cognitive Functions in the Hippocampus Induced by Exposure to a Chronic High-Altitude Hypoxia Environment.
Topics: Altitude Sickness; Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Caspase 3; Catechin; Cognition; Hippocampus; Hypoxia; Iron; Maze Learning; Neurons; Oxidative Stress; Rats; Regeneration | 2022 |
(-)-Epigallocatechin Gallate Attenuates Spinal Motoneuron Death Induced by Brachial Plexus Root Avulsion in Rats.
Topics: Animals; Brachial Plexus; Caspase 3; Catechin; Motor Neurons; Rats; Rats, Sprague-Dawley | 2022 |
Oral antimicrobial peptide-EGCG nanomedicines for synergistic treatment of ulcerative colitis.
Topics: Animals; Antimicrobial Peptides; Catechin; Colitis; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Inflammation; Lipopolysaccharides; Mice; Nanomedicine; RAW 264.7 Cells | 2022 |
Protective effects of epigallocatechin-3-o-gallate combined with organic selenium against transforming growth factor-beta 1-induced fibrosis in LX-2 cells.
Topics: Antioxidants; Catechin; Cell Line; Fibrosis; Humans; Selenium; Selenomethionine; Tea; Transforming Growth Factor beta1 | 2022 |
Epigallocatechin gallate-loaded tetrahedral DNA nanostructures as a novel inner ear drug delivery system.
Topics: Animals; Catechin; DNA; Drug Delivery Systems; Ear, Inner; Guinea Pigs; Mice; Nanostructures | 2022 |
Epigallocatechin-3-gallate inhibits osteopontin expression and prevents experimentally induced hepatic fibrosis.
Topics: Animals; Body Weight; Catechin; Collagen Type I; Collagen Type IV; Dimethylnitrosamine; Fibrosis; Hepatic Stellate Cells; Hyaluronic Acid; Liver; Liver Cirrhosis; Malondialdehyde; Osteopontin; Rats | 2022 |
The effects of Epigallocatechin-3-gallate and Dabrafenib combination on apoptosis and the genes involved in epigenetic events in anaplastic thyroid cancer cells.
Topics: Apoptosis; Catechin; Cell Line, Tumor; Epigenesis, Genetic; Humans; Imidazoles; Oximes; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms | 2022 |
The Importance of Val386 in Transmembrane Domain 8 for the Activation of OATP1B3 by Epigallocatechin Gallate.
Topics: Biological Transport; Catechin; Kinetics; Liver-Specific Organic Anion Transporter 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Solute Carrier Organic Anion Transporter Family Member 1B3 | 2022 |
Lipids and EGCG Affect α-Synuclein Association and Disruption of Nanodiscs.
Topics: alpha-Synuclein; Catechin; Glycerol; Lipid Bilayers; Lipids | 2022 |
Long-term consumption of green tea EGCG enhances murine health span by mitigating multiple aspects of cellular senescence in mitotic and post-mitotic tissues, gut dysbiosis, and immunosenescence.
Topics: AMP-Activated Protein Kinases; Animals; Catechin; Cellular Senescence; Dysbiosis; Immunosenescence; Mice; Proto-Oncogene Proteins c-akt; Sirtuin 3; Tea | 2022 |
Comparative and Combined Effects of Epigallocatechin-3-gallate and Caffeine in Reducing Lipid Accumulation in Caenorhabditis elegans.
Topics: Animals; Caenorhabditis elegans; Caffeine; Catechin; Cholesterol; Triglycerides | 2022 |
Multidrug resistance-associated protein 2 (MRP2) is an efflux transporter of EGCG and its metabolites in the human small intestine.
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; Biological Transport; Caco-2 Cells; Catechin; Humans; Intestine, Small; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Quercetin; Tea | 2022 |
Epigallocatechin gallate relieves asthmatic symptoms in mice by suppressing HIF-1α/VEGFA-mediated M2 skewing of macrophages.
Topics: Animals; Asthma; Catechin; Hypoxia-Inducible Factor 1, alpha Subunit; Macrophages; Mice; Pyroglyphidae; Vascular Endothelial Growth Factor A | 2022 |
Higher affinity of polyphenol to zein than to amyloid fibrils leading to nanoparticle-embed network wall scaffold to construct amyloid fibril-zein-EGCG hydrogels for coating of beef.
Topics: Amyloid; Animals; Catechin; Cattle; Hydrogels; Micronutrients; Nanoparticles; Polyphenols; Zein | 2022 |
Virucidal activities of novel hand hygiene and surface disinfectant formulations containing EGCG-palmitates (EC16).
Topics: Animals; Calicivirus, Feline; Catechin; Cats; Disinfectants; Ethanol; Hand Hygiene; Humans; Mice; Norovirus | 2022 |
Multispectroscopic and computational simulation insights into the inhibition mechanism of epigallocatechin-3-gallate on polyphenol oxidase.
Topics: Catechin; Catechol Oxidase; Molecular Docking Simulation; Protein Structure, Secondary | 2022 |
Tea polyphenol epigallocatechin-3-gallate inhibits cell proliferation in a patient-derived triple-negative breast cancer xenograft mouse model via inhibition of proline-dehydrogenase-induced effects.
Topics: Animals; Catechin; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Heterografts; Humans; Mice; Polyphenols; Proline; Proline Oxidase; Tea; Triple Negative Breast Neoplasms | 2021 |
l-Theanine Inhibits (-)-Epigallocatechin-3-gallate Oxidation via Chelating Copper.
Topics: Animals; Catechin; Chelating Agents; Copper; Dopamine; Glutamates; Mice; Oxidation-Reduction; Tea | 2022 |
Attenuation of methotrexate induced hepatotoxicity by epigallocatechin 3-gallate.
Topics: Alkaline Phosphatase; Animals; Antioxidants; Catechin; Chemical and Drug Induced Liver Injury; Liver; Methotrexate; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rats, Wistar | 2023 |
Autoxidation-Resistant, ROS-Scavenging, and Anti-Inflammatory Micellar Nanoparticles Self-Assembled from Poly(acrylic acid)-Green Tea Catechin Conjugates.
Topics: Acrylic Resins; Anti-Inflammatory Agents; Catechin; Micelles; Nanoparticles; Reactive Oxygen Species; Tea | 2022 |
Chitosan-Gelatin-EGCG Nanoparticle-Meditated LncRNA TMEM44-AS1 Silencing to Activate the P53 Signaling Pathway for the Synergistic Reversal of 5-FU Resistance in Gastric Cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Catechin; Cell Line, Tumor; Chitosan; Drug Resistance, Neoplasm; Fluorouracil; Gelatin; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; MicroRNAs; Nanoparticles; Repressor Proteins; RNA; RNA, Antisense; RNA, Long Noncoding; Signal Transduction; Stomach Neoplasms; Tumor Suppressor Protein p53 | 2022 |
An insight into the changes in conformation and emulsifying properties of soy β-conglycinin and glycinin as affected by EGCG: Multi-spectral analysis.
Topics: Antigens, Plant; Catechin; Globulins; Seed Storage Proteins; Soybean Proteins | 2022 |
Repigmentation in two patients with vitiligo on AcEGCG 0.5% cream.
Topics: Catechin; Emollients; Humans; Melanocytes; Oxidative Stress; Skin Pigmentation; Vitiligo | 2022 |
Development and application of hydrophilic-hydrophobic dual-protein Pickering emulsifiers: EGCG-modified caseinate-zein complexes.
Topics: Caseins; Catechin; Emulsifying Agents; Emulsions; Hydrophobic and Hydrophilic Interactions; Zein | 2022 |
PLAGL1 Gene Demethylation Induced by Epigallocatechin Gallate Promotes Pheochromocytoma Cell Apoptosis Via Wnt/β-catenin Signaling Pathway.
Topics: Adrenal Gland Neoplasms; Animals; Apoptosis; beta Catenin; Catechin; Cell Cycle Proteins; Demethylation; Genes, Tumor Suppressor; Humans; PC12 Cells; Pheochromocytoma; Rats; RNA, Messenger; Transcription Factors; Tumor Suppressor Proteins; Wnt Signaling Pathway | 2022 |
Photochemoprevention of ultraviolet Beam Radiation-induced DNA damage in keratinocytes by topical delivery of nanoformulated Epigallocatechin-3-gallate.
Topics: Animals; Antioxidants; Catechin; DNA Damage; Humans; Keratinocytes; Mice; Mice, Hairless; Skin; Ultraviolet Rays | 2022 |
Epigallocatechin-3-gallate ameliorates renal endoplasmic reticulum stress-mediated inflammation in type 2 diabetic rats.
Topics: Animals; Catechin; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endoplasmic Reticulum Stress; Hyperglycemia; Inflammasomes; Inflammation; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Tea | 2022 |
EGCG-coated silver nanoparticles self-assemble with selenium nanowires for treatment of drug-resistant bacterial infections by generating ROS and disrupting biofilms.
Topics: Anti-Bacterial Agents; Bacterial Infections; Biofilms; Catechin; Escherichia coli; Humans; Metal Nanoparticles; Nanowires; Reactive Oxygen Species; Selenium; Silver; Staphylococcus aureus | 2022 |
EGCG and catechin relative to green tea extract differentially modulate the gut microbial metabolome and liver metabolome to prevent obesity in mice fed a high-fat diet.
Topics: Animals; Antioxidants; Catechin; Diet, High-Fat; Gastrointestinal Microbiome; Liver; Male; Metabolome; Mice; Mice, Inbred C57BL; Obesity; Plant Extracts; Tea; Tyrosine | 2022 |
4″-Sulfation Is the Major Metabolic Pathway of Epigallocatechin-3-gallate in Humans: Characterization of Metabolites, Enzymatic Analysis, and Pharmacokinetic Profiling.
Topics: Catechin; Humans; Metabolic Networks and Pathways; Sulfates; Tea | 2022 |
3D printed PCLA scaffold with nano-hydroxyapatite coating doped green tea EGCG promotes bone growth and inhibits multidrug-resistant bacteria colonization.
Topics: Anti-Bacterial Agents; Bone Regeneration; Caproates; Catechin; Dioxanes; Durapatite; Lactones; Methicillin-Resistant Staphylococcus aureus; Osteogenesis; Polymerization; Polyphenols; Printing, Three-Dimensional; Tea; Tissue Engineering; Tissue Scaffolds; Water | 2022 |
Epigallocatechin-3-gallate Induced HepG2 Cells Apoptosis through ROSmediated AKT /JNK and p53 Signaling Pathway.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Hep G2 Cells; Humans; Liver Neoplasms; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Tumor Suppressor Protein p53 | 2023 |
Biopolymeric composite hydrogel loaded with silver NPs and epigallocatechin gallate (EGCG) effectively manages ROS for rapid wound healing in type II diabetic wounds.
Topics: Animals; Catechin; Diabetes Mellitus, Type 2; Hydrogels; Mice; Mice, Inbred C57BL; Reactive Oxygen Species; Silver; Wound Healing | 2022 |
Interactions of (-)-epigallocatechin-3-gallate with model lipid membranes.
Topics: Antioxidants; Catechin; Lipids; Liposomes | 2022 |
Epigallocatechin-3-Gallate Pretreatment Improves Autologous Adipose-derived Stem Cells Against Rheumatoid Arthritis-induced Neuroinflammation in the Brain of Collagen-induced Rats.
Topics: Animals; Antioxidants; Arthritis, Rheumatoid; Brain; Catechin; Collagen; Neuroinflammatory Diseases; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Stem Cells; Tea | 2022 |
Epigallocatechin gallate (EGCG) attenuates severe acute respiratory coronavirus disease 2 (SARS-CoV-2) infection by blocking the interaction of SARS-CoV-2 spike protein receptor-binding domain to human angiotensin-converting enzyme 2.
Topics: Angiotensin-Converting Enzyme 2; Caco-2 Cells; Catechin; COVID-19; COVID-19 Drug Treatment; Humans; Molecular Docking Simulation; Peptidyl-Dipeptidase A; Protein Binding; SARS-CoV-2; Spike Glycoprotein, Coronavirus | 2022 |
Enzymatic Synthesis and Antioxidant Activity of Mono- and Diacylated Epigallocatechin Gallate and Related By-Products.
Topics: Antioxidants; Catechin; Esters; Gallic Acid; Oxidation-Reduction; Water | 2022 |
Epigallocatechin-3-gallate attenuates myocardial fibrosis in diabetic rats by activating autophagy.
Topics: Adenosine; AMP-Activated Protein Kinases; Animals; Autophagy; Beclin-1; Blood Glucose; Catechin; Collagen; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Fibrosis; Hydroxyproline; Hypertrophy; Mammals; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Microtubule-Associated Proteins; Rats; TOR Serine-Threonine Kinases; Transforming Growth Factor beta1 | 2022 |
Epigallocatechin gallate (EGCG) modification of structural and functional properties of whey protein isolate.
Topics: Catechin; Emulsions; Hydrophobic and Hydrophilic Interactions; Whey Proteins | 2022 |
Dual stabilization of Pickering emulsion with epigallocatechin gallate loaded mesoporous silica nanoparticles.
Topics: Antioxidants; Catechin; Emulsions; Nanoparticles; Oils, Volatile; Particle Size; Silicon Dioxide | 2022 |
EGCG exposure during pregnancy affects uterine histomorphology in F1 female mice and the underlying mechanisms.
Topics: Animals; Atrophy; Catechin; Female; Fibrosis; Inflammation; Mice; Mice, Inbred C57BL; Pregnancy; Tea | 2022 |
Epigallocatechin-3-gallate exerts protective effect on epithelial function via PI3K/AKT signaling in thrombosis.
Topics: Animals; Apoptosis; Catechin; Interleukin-6; Interleukin-8; Myocardial Reperfusion Injury; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Superoxide Dismutase; Thrombosis; Tumor Necrosis Factor-alpha | 2022 |
Green tea epigallocatechin gallate suppresses 3T3-L1 cell growth via microRNA-143/MAPK7 pathways.
Topics: 3T3-L1 Cells; Animals; Catechin; Mice; MicroRNAs; RNA, Messenger; Tea | 2022 |
The green tea catechin EGCG provides proof-of-concept for a pan-coronavirus attachment inhibitor.
Topics: Animals; Antiviral Agents; Catechin; COVID-19 Drug Treatment; Heparitin Sulfate; Humans; Mice; Pandemics; SARS-CoV-2; Tea | 2022 |
Gum tragacanth-sodium alginate active coatings containing epigallocatechin gallate reduce hydrogen peroxide content and inhibit lipid and protein oxidations of large yellow croaker (Larimichthys crocea) during superchilling storage.
Topics: Alginates; Animals; Catechin; Hydrogen Peroxide; Lipids; Perciformes; Tragacanth; Water | 2022 |
Antioxidation Function of EGCG by Activating Nrf2/HO-1 Pathway in Mice with Coronary Heart Disease.
Topics: Animals; Antioxidants; Catechin; Cholesterol; Coronary Disease; Lipids; Matrix Metalloproteinase 2; Mice; NF-E2-Related Factor 2; Sodium Cholate; Vascular Endothelial Growth Factor A | 2022 |
Co-amorphous systems using epigallocatechin-3-gallate as a co-former: Stability, in vitro dissolution, in vivo bioavailability and underlying molecular mechanisms.
Topics: Animals; Biological Availability; Calorimetry, Differential Scanning; Catechin; Drug Stability; Nifedipine; Rats; Simvastatin; Solubility; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2022 |
Effect of Epigallocatechin-3-gallate on Stress-Induced Depression in a Mouse Model: Role of Interleukin-1β and Brain-Derived Neurotrophic Factor.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antioxidants; Brain-Derived Neurotrophic Factor; Catechin; Clomipramine; Depression; Disease Models, Animal; Hippocampus; Interleukin-1beta; Mice; RNA, Messenger; Stress, Psychological; Tea | 2022 |
Effect of epigallocatechin gallate on the fermentative and physicochemical properties of fermented milk.
Topics: Acids; Animals; Antioxidants; Catechin; Fermentation; Lactobacillus delbrueckii; Milk; Streptococcus thermophilus; Water; Yogurt | 2022 |
Metagenomics Approach to the Intestinal Microbiome Structure and Abundance in High-Fat-Diet-Induced Hyperlipidemic Rat Fed with (-)-Epigallocatechin-3-Gallate Nanoparticles.
Topics: Animals; Catechin; Cholesterol; Diet, High-Fat; Gastrointestinal Microbiome; Hyperlipidemias; Metagenomics; Molecular Docking Simulation; Nanoparticles; Rats; Spectroscopy, Fourier Transform Infrared | 2022 |
Ultrasound-assisted preparation of lactoferrin-EGCG conjugates and their application in forming and stabilizing algae oil emulsions.
Topics: Antioxidants; Catechin; Emulsions; Lactoferrin; Polyphenols | 2022 |
Dimeric-(-)-epigallocatechin-3-gallate inhibits the proliferation of lung cancer cells by inhibiting the EGFR signaling pathway.
Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Lung Neoplasms; Signal Transduction | 2022 |
Epigallocatechin gallate is a potent inhibitor of cystathionine beta-synthase: Structure-activity relationship and mechanism of action.
Topics: Catechin; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Humans; Hydrogen Sulfide; Phosphates; Pyridoxal; Structure-Activity Relationship | 2022 |
Epigallocatechin-3-gallate attenuates cyclophosphamide-induced damage in mouse ovarian tissue via suppressing inflammation, apoptosis, and expression of phosphorylated Akt, FOXO3a and rpS6.
Topics: Acetylcysteine; Animals; Apoptosis; Body Weight; Caspase 3; Catechin; Cyclophosphamide; Female; Inflammation; Mice; Proto-Oncogene Proteins c-akt; Saline Solution; Tumor Necrosis Factor-alpha | 2022 |
Effect of Green Tea and Tea Catechin on the Visual Motion Processing for Optokinetic Responses in Mice.
Topics: Animals; Antioxidants; Catechin; Humans; Mice; Plant Extracts; Polyphenols; Powders; Tea | 2022 |
Antimicrobial Effect of Epigallocatechin Gallate Against Shewanella putrefaciens ATCC 8071: A Study Based on Cell Membrane and Biofilm.
Topics: Animals; Anti-Infective Agents; Biofilms; Catechin; Cell Membrane; Shewanella putrefaciens | 2022 |
Improving the
Topics: Animals; Biological Availability; Caco-2 Cells; Catechin; Corn Oil; Delayed-Action Preparations; Emulsions; Excipients; Gonads; Humans; Mice; Micelles; Oils; Pectinidae; Proteins; Stilbenes | 2022 |
The Gut Microbial Metabolite Pyrogallol Is a More Potent Inducer of Nrf2-Associated Gene Expression Than Its Parent Compound Green Tea (-)-Epigallocatechin Gallate.
Topics: Catechin; Catechols; Gallic Acid; Gastrointestinal Microbiome; Gene Expression; NF-E2-Related Factor 2; Pyrogallol; Tea | 2022 |
Characterization of whey protein isolate-(-)-epigallocatechin-3-gallate conjugates prepared by non-enzymatic and enzymatic methods and their application in stabilizing β-carotene emulsion.
Topics: Antioxidants; beta Carotene; Catechin; Emulsions; Whey Proteins | 2023 |
Rhabdomyolysis-induced acute kidney injury and concomitant apoptosis induction via ROS-mediated ER stress is efficaciously counteracted by epigallocatechin gallate.
Topics: Acute Kidney Injury; Animals; Apoptosis; Catechin; Endoplasmic Reticulum Stress; Glycerol; HEK293 Cells; Humans; Hydrogen Peroxide; Male; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Rhabdomyolysis; Tumor Suppressor Protein p53 | 2022 |
Effects of artificial honey and epigallocatechin-3-gallate on streptococcus pyogenes.
Topics: Animals; Biofilms; Catechin; Honey; Humans; Male; Pharyngitis; Streptococcus pyogenes; Tea | 2022 |
Elaboration of Cationic Soluble Soybean Polysaccharides-Epigallocatechin Gallate Nanoparticles with Sustained Antioxidant and Antimicrobial Activities.
Topics: Anti-Infective Agents; Antioxidants; Catechin; Cations; Glycine max; Nanoparticles; Polysaccharides | 2022 |
Epigallocatechin-3-gallate (EGCG) attenuates inflammatory responses and oxidative stress in lipopolysaccharide (LPS)-induced endometritis via silent information regulator transcript-1 (SIRT1)/nucleotide oligomerization domain (NOD)-like receptor pyrin dom
Topics: Animals; Carrier Proteins; Catechin; Cattle; Cytokines; Endometritis; Female; Inflammasomes; Lipopolysaccharides; Mice; Mice, Inbred BALB C; NLR Family, Pyrin Domain-Containing 3 Protein; Nucleotides; Oxidative Stress; Pyrin Domain; Sirtuin 1 | 2022 |
Effect of a chitosan coating incorporating epigallocatechin gallate on the quality and shelf life of bighead carp (Aristichthys nobilis) fillets during chilled storage.
Topics: Animals; Carps; Catechin; Chitosan; Food Preservation; Food Storage; Glycerol; Nitrogen | 2022 |
Targeting Glutaminolysis to Treat Multiple Myeloma: An
Topics: Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Glutaminase; Glutamine; Humans; Multiple Myeloma; Proto-Oncogene Proteins c-bcl-2 | 2023 |
Protective Effects of Epigallocatechin Gallate for Male Sexual Dysfunction in Streptozotocin-Induced Diabetic Rats.
Topics: Animals; Blood Glucose; Catechin; Diabetes Mellitus, Experimental; Humans; Male; Rats; Streptozocin | 2022 |
A Combination Therapy of Urolithin A+EGCG Has Stronger Protective Effects than Single Drug Urolithin A in a Humanized Amyloid Beta Knockin Mice for Late-Onset Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Catechin; Coumarins; Humans; Mice; Mitochondrial Dynamics; RNA, Messenger | 2022 |
Biological Effects of EGCG@MOF Zn(BTC)
Topics: Animals; Catechin; Diabetes Mellitus; Mice; Tea; Wound Healing; Zinc | 2022 |
Exploring The Relative Astringency of Tea Catechins and Distinct Astringent Sensation of Catechins and Flavonol Glycosides via an In Vitro Assay Composed of Artificial Oil Bodies.
Topics: Astringents; Catechin; Flavonols; Glycosides; Humans; Lipid Droplets; Sensation; Tea | 2022 |
Mechanism of (-)-epigallocatechin gallate (EGCG) dimerization by low-temperature plasma.
Topics: Catechin; Dimerization; Formaldehyde; Ozone; Temperature | 2022 |
Antitumor/anti-angiogenesis efficacy of epigallocatechin gallate nanoformulated with antioxidant in melanoma.
Topics: Antioxidants; Catechin; Humans; Lycopene; Melanoma; Olive Oil; Tea; Zinc Oxide | 2022 |
Epigallocatechin-3-gallate inhibits the formation of neutrophil extracellular traps and suppresses the migration and invasion of colon cancer cells by regulating STAT3/CXCL8 pathway.
Topics: Catechin; Colonic Neoplasms; Deoxyribonuclease I; Extracellular Traps; Humans; Neutrophils; STAT3 Transcription Factor; Tea; Tumor Necrosis Factor-alpha | 2023 |
Epigallocatechin-3-gallate ameliorates liver injury secondary to Pseudomonas aeruginosa pneumonia.
Topics: Alanine Transaminase; Animals; Anti-Bacterial Agents; Aspartate Aminotransferases; Catechin; Cytokines; Interleukin-6; Liver; Liver Diseases; Mice; Myeloid Differentiation Factor 88; NF-kappa B; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2022 |
Structure-based discovery of small molecules that disaggregate Alzheimer's disease tissue derived tau fibrils in vitro.
Topics: Alzheimer Disease; Amyloid; Amyloidosis; Catechin; Cryoelectron Microscopy; Drug Evaluation, Preclinical; Humans; tau Proteins; Tea | 2022 |
Green Tea Catechol (-)-Epigallocatechin Gallate (EGCG) Conjugated with Phenylalanine Shows Enhanced Autophagy Stimulating Activity in Human Aortic Endothelial Cells.
Topics: Autophagy; Catechin; Catechols; Endothelial Cells; Humans; Phenylalanine; Tea | 2023 |
Preventive Effect of Epigallocatechin Gallate, the Main Component of Green Tea, on Acute Lung Injury Caused by Air Pollutants.
Topics: Acute Lung Injury; Air Pollutants; Animals; Antioxidants; Catechin; Cytokines; Mice; Mice, Inbred ICR; Particulate Matter; Reactive Oxygen Species; Respiratory Aerosols and Droplets; Tea | 2022 |
Comparison of soy protein isolate-(-)-epigallocatechin gallate complexes prepared by mixing, chemical polymerization, and ultrasound treatment.
Topics: Antioxidants; Catechin; Polymerization; Polyphenols; Soybean Proteins | 2022 |
The combination of EGCG with warfarin reduces deep vein thrombosis in rabbits through modulating HIF-1α and VEGF via the PI3K/AKT and ERK1/2 signaling pathways.
Topics: Animals; Anticoagulants; Catechin; Eosine Yellowish-(YS); Fibrinogen; Hematoxylin; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Hypoxia-Inducible Factor 1, alpha Subunit; MAP Kinase Signaling System; Phosphatidylinositol 3-Kinases; Polyphenols; Proto-Oncogene Proteins c-akt; Rabbits; Rats; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Tea; Thrombin; Vascular Endothelial Growth Factor A; Venous Thrombosis; Warfarin | 2022 |
Fabrication and characterization of gelatin-EGCG-pectin ternary complex: formation mechanism, emulsion stability, and structure.
Topics: Catechin; Emulsions; Gelatin; Pectins; Polyphenols; Polysaccharides | 2023 |
Epigallocatechin-3-gallate suppresses hemin-aggravated colon carcinogenesis through Nrf2-inhibited mitochondrial reactive oxygen species accumulation.
Topics: Animals; Antioxidants; Azoxymethane; Caco-2 Cells; Carcinogenesis; Catechin; Cell Cycle Proteins; Colon; Dextrans; Hemin; Humans; Iron; Kelch-Like ECH-Associated Protein 1; Lactate Dehydrogenases; Malondialdehyde; Mice; NF-E2-Related Factor 2; Reactive Oxygen Species; Rodent Diseases; Tea; Tetrazolium Salts | 2022 |
Limited hydrolysis as a strategy to improve the non-covalent interaction of epigallocatechin-3-gallate (EGCG) with whey protein isolate near the isoelectric point.
Topics: Catechin; Hydrolysis; Isoelectric Point; Protein Hydrolysates; Tryptophan; Whey Proteins | 2022 |
Epigallocatechin-3-gallate alleviates galactose-induced aging impairment
Topics: Aging; Animals; Brain; Catechin; Disease Models, Animal; Galactose; Hypothalamo-Hypophyseal System; Mice; Pituitary-Adrenal System; Tea | 2022 |
Prenatal EGCG consumption causes obesity and perturbs glucose homeostasis in adult mice.
Topics: Adult; Animals; Catechin; Female; Glucose; Homeostasis; Male; Mice; Mice, Inbred C57BL; Obesity; Pregnancy; Prenatal Exposure Delayed Effects; Receptor, Insulin | 2023 |
EGCG has Dual and Opposing Effects on the N-terminal Region of Self-associating α-synuclein Oligomers.
Topics: alpha-Synuclein; Catechin; Humans; Oxidation-Reduction; Parkinson Disease; Protein Conformation; Protein Folding | 2022 |
Use of Physiologically Based Kinetic Modeling-Based Reverse Dosimetry to Predict
Topics: Catechin; Colon; Gallic Acid; Humans; Kinetics; NF-E2-Related Factor 2 | 2022 |
An in silico investigation on the interactions of curcumin and epigallocatechin-3-gallate with NLRP3 Inflammasome complex.
Topics: Catechin; Curcumin; Inflammasomes; Interleukin-18; Interleukin-1beta; Molecular Docking Simulation; NLR Family, Pyrin Domain-Containing 3 Protein; Polyphenols | 2022 |
Epigallocatechin-3-gallate inhibits osteoclastic differentiation by modulating mitophagy and mitochondrial functions.
Topics: Catechin; Mitochondria; Mitophagy; Osteogenesis; Reactive Oxygen Species | 2022 |
(-)-Epigallocatechin gallate (EGCG) pharmacokinetics and molecular interactions towards amelioration of hyperglycemia, hyperlipidemia associated hepatorenal oxidative injury in alloxan induced diabetic mice.
Topics: Alloxan; Animals; Antioxidants; Blood Glucose; Catechin; Diabetes Mellitus, Experimental; Hyperglycemia; Hyperlipidemias; Liver; Mice; Oxidative Stress | 2022 |
Self-Assembled Integrative Nutrient Carrier Platform Containing Green Tea Catechin for Short Bowel Syndrome Treatment.
Topics: Animals; Catechin; Nutrients; Phenols; Rats; Short Bowel Syndrome; Tea | 2023 |
Epigallocatechin-3-gallate protects porcine oocytes against post-ovulatory aging through inhibition of oxidative stress.
Topics: Aging; Animals; Catechin; Glutathione; Oocytes; Oxidative Stress; Swine | 2022 |
Epigallocatechin-3-gallate Enhances Cognitive and Memory Performance and Protects Against Brain Injury in Methionine-induced Hyperhomocysteinemia Through Interdependent Molecular Pathways.
Topics: Animals; Apoptosis Regulatory Proteins; Brain Injuries; Catechin; Cognition; Hyperhomocysteinemia; Male; Methionine; Mice; Oxidative Stress; Racemethionine | 2022 |
Epigallocatechin gallate-derived carbonized polymer dots: A multifunctional scavenger targeting Alzheimer's β-amyloid plaques.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Carbon; Catechin; Humans; Plaque, Amyloid | 2023 |
EGCG inactivates a pore-forming toxin by promoting its oligomerization and decreasing its solvent-exposed hydrophobicity.
Topics: Animals; Bee Venoms; Catechin; Hydrophobic and Hydrophilic Interactions; Melitten; Solvents | 2023 |
Green Tea Catechin EGCG Ameliorates Thioacetamide-Induced Hepatic Encephalopathy in Rats via Modulation of the Microbiota-Gut-Liver Axis.
Topics: Animals; Antioxidants; Catechin; Gastrointestinal Microbiome; Hepatic Encephalopathy; Rats; RNA, Ribosomal, 16S; Tea; Thioacetamide | 2023 |
Soluble dietary fibres decrease α-glucosidase inhibition of epigallocatechin gallate through affecting polyphenol-enzyme binding interactions.
Topics: alpha-Glucosidases; Catechin; Dietary Fiber; Polyphenols | 2023 |
Epigallocatechin-3-gallate and resveratrol attenuate hydrogen peroxide induced damage in neuronal cells.
Topics: Apoptosis; Caspase 3; Catechin; Humans; Hydrogen Peroxide; Neuroblastoma; Resveratrol | 2023 |
EGCG inhibits hypertrophic scar formation in a rabbit ear model.
Topics: Animals; Catechin; Cicatrix, Hypertrophic; Collagen; Fibrosis; Mice; Rabbits; Rats; RNA, Messenger | 2023 |
Self-Assembled Daunorubicin/Epigallocatechin Gallate Nanocomplex for Synergistic Reversal of Chemoresistance in Leukemia.
Topics: Apoptosis; Catechin; Daunorubicin; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; Tea | 2022 |
Effects of simultaneous versus post exposure epigallocatechin-3-gallate treatment on aluminum induced neurotoxicity in rat hippocampus: A multi-approach study.
Topics: Acetylcholinesterase; Aluminum; Animals; Antioxidants; Catechin; Hippocampus; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Rats; Rats, Wistar | 2023 |
Stability of glycosylated complexes loaded with Epigallocatechin 3-gallate (EGCG).
Topics: Catechin; Drug Stability; Glycoproteins; Glycosylation; Nanoparticles | 2023 |
EGCG attenuates α-synuclein protofibril-membrane interactions and disrupts the protofibril.
Topics: alpha-Synuclein; Catechin; Humans; Membranes; Parkinson Disease | 2023 |
Nanoprecipitates of γ-cyclodextrin/epigallocatechin-3-gallate inclusion complexes as efficient antioxidants for preservation of shrimp surimi products: synthesis, performance and mechanism.
Topics: Antioxidants; Catechin; gamma-Cyclodextrins; Molecular Conformation | 2023 |
Epigallocatechin gallate improves the quality of diabetic oocytes.
Topics: Animals; Antioxidants; Catechin; Diabetes, Gestational; Female; Humans; Mice; Oocytes; Pregnancy | 2023 |
(-)-Epigallocatechin-3-gallate, a Polyphenol from Green Tea, Regulates the Liquid-Liquid Phase Separation of Alzheimer's-Related Protein Tau.
Topics: Alzheimer Disease; Catechin; Humans; Polyphenols; tau Proteins; Tea | 2023 |
Epigallocatechin gallate inhibits Francisella tularensis growth and suppresses the function of DNA-binding protein HU.
Topics: Animals; Catechin; DNA-Binding Proteins; Francisella tularensis; Mice; Tularemia | 2023 |
Zinc-Epigallocatechin-3-gallate Network-Coated Nanocomposites against the Pathogenesis of Amyloid-Beta.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Catechin; Gold; Humans; Metal Nanoparticles; Zinc | 2023 |
Quantification of Risperidone Contained in Precipitates Produced by Tea Catechins Using Nuclear Magnetic Resonance.
Topics: Catechin; Humans; Magnetic Resonance Spectroscopy; Risperidone; Tea | 2023 |
Single-step assembly of lipid-gelatin-epigallocatechin-3-gallate hybrid nanoparticles for cancer therapy.
Topics: Animals; Catechin; Drug Carriers; Gelatin; Lipids; Mice; Nanoparticles; Neoplasms | 2023 |
Formation Mechanism of Di-
Topics: Camellia sinensis; Catechin; Tea; Temperature | 2023 |
Chlorogenic acid combined with epigallocatechin-3-gallate mitigates D-galactose-induced gut aging in mice.
Topics: Aging; Animals; Antioxidants; Catechin; Chlorogenic Acid; Galactose; Mice | 2023 |
EGCG alleviated Mn exposure-caused carp kidney damage via trpm2-NLRP3-TNF-α-JNK pathway: Oxidative stress, inflammation, and tight junction dysfunction.
Topics: Animals; Carps; Catechin; Inflammation; Kidney; Kidney Diseases; Manganese; MAP Kinase Signaling System; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Tight Junctions; Tumor Necrosis Factor-alpha | 2023 |
Effects of Green Tea Polyphenol Epigallocatechin-3-Gallate on Markers of Inflammation and Fibrosis in a Rat Model of Pulmonary Silicosis.
Topics: Animals; Catechin; Fibrosis; Inflammation; Lung; Polyphenols; Rats; Silicon Dioxide; Silicosis; Tea | 2023 |
Engineering Interfacial Environment of Epigallocatechin Gallate Coated Titanium for Next-Generation Bioactive Dental Implant Components.
Topics: Antioxidants; Catechin; Dental Implants; Polyphenols; Surface Properties; Titanium | 2023 |
Effect of Alleviating Fibrosis with EGCG-Modified Bone Graft in Murine Model Depended on Less Accumulation of Inflammatory Macrophage.
Topics: Animals; Bone Regeneration; Capsules; Catechin; Disease Models, Animal; Durapatite; Macrophages; Mice; Osteogenesis | 2023 |
Green Tea Epigallocatechin Gallate Inhibits Preadipocyte Growth via the microRNA-let-7a/HMGA2 Signaling Pathway.
Topics: Catechin; Cell Proliferation; MicroRNAs; RNA, Messenger; Signal Transduction; Tea | 2023 |
Epigallocatechin-3-gallate (EGCG) based metal-polyphenol nanoformulations alleviates chondrocytes inflammation by modulating synovial macrophages polarization.
Topics: Anti-Inflammatory Agents; Antioxidants; Catechin; Chondrocytes; Humans; Hydrogen Peroxide; Inflammation; Macrophages; Osteoarthritis; Polyphenols; Reactive Oxygen Species | 2023 |
Epigallocatechin gallate prevents peritoneal fibrosis by inhibiting epithelial-mesenchymal transition in human peritoneal mesothelial cells.
Topics: Cadherins; Catechin; Epithelial-Mesenchymal Transition; Humans; Peritoneal Fibrosis | 2022 |
The inhibition effects of chlorogenic acid on the formation of colored oxidation products of (-)-epigallocatechin gallate under enzymatic oxidation.
Topics: Catechin; Chlorogenic Acid; Mass Spectrometry; Oxidation-Reduction; Tea | 2023 |
An EGCG-mediated self-assembled micellar complex acts as a bioactive drug carrier.
Topics: Catechin; Drug Carriers; Micelles; Paclitaxel; Water | 2023 |
Targeting the TNF-α-TNFR interaction with EGCG to block NF-κB signaling in human synovial fibroblasts.
Topics: Catechin; Cells, Cultured; Fibroblasts; Humans; NF-kappa B; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Signal Transduction; Tea; Tumor Necrosis Factor-alpha | 2023 |
Influence of environmental pH on the interaction properties of WP-EGCG non-covalent nanocomplexes.
Topics: Antioxidants; Catechin; Hydrogen-Ion Concentration; Molecular Docking Simulation; Whey Proteins | 2023 |
Epigallocatechin Gallate: pH-Dependent Redox Properties and Effect on Respiration, Photosynthesis, and Cell Death in Pea Plants.
Topics: Apoptosis; Catechin; Cell Death; Electron Transport; Hydrogen Peroxide; Hydrogen-Ion Concentration; Photosynthesis; Pisum sativum; Reactive Oxygen Species; Respiration | 2023 |
Tea polyphenol EGCG ameliorates obesity-related complications by regulating lipidomic pathway in leptin receptor knockout rats.
Topics: Animals; Catechin; Cholesterol; Glycerophospholipids; Lipidomics; Liver; Obesity; Polyphenols; Rats; Receptors, Leptin; Tea; Triglycerides | 2023 |
Epigallocatechin-3-gallate in combination with corticosteroids mitigates heat stress-induced acute kidney injury through modulating heat shock protein 70 and toll-like receptor 4-dependent pathways.
Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Animals; Antineoplastic Agents; Antioxidants; Catechin; NF-kappa B; Rats; Toll-Like Receptor 4 | 2023 |
Protective Effects of Epigallocatechin-3-gallate (EGCG) against the Jellyfish
Topics: Animals; Catechin; Cnidaria; Cnidarian Venoms; Scyphozoa | 2023 |
Epigallocatechin-3-Gallate Alleviates Liver Oxidative Damage Caused by Iron Overload in Mice through Inhibiting Ferroptosis.
Topics: Animals; Antioxidants; Catechin; Ferroptosis; Iron Overload; Liver Diseases; Mice; Oxidative Stress | 2023 |
Amelioration of ovalbumin gel properties by EGCG via protein aggregation, hydrogen, and van der Waals force.
Topics: Catechin; Computer Simulation; Hydrogen; Ovalbumin; Protein Aggregates | 2023 |
The polyphenol EGCG directly targets intracellular amyloid-β aggregates and promotes their lysosomal degradation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Catechin; Humans; Lysosomes | 2023 |
(-)-Epigallocatechin-3-Gallate Attenuates the Adverse Reactions Triggered by Selenium Nanoparticles without Compromising Their Suppressing Effect on Peritoneal Carcinomatosis in Mice Bearing Hepatocarcinoma 22 Cells.
Topics: Animals; Catechin; Diarrhea; Mice; Nanoparticles; Neoplasms; Polyphenols; Selenium; Tea | 2023 |
Co-assembled nanocomplexes comprising epigallocatechin gallate and berberine for enhanced antibacterial activity against multidrug resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Berberine; Catechin; Methicillin-Resistant Staphylococcus aureus; Mice; Nanocomposites; Staphylococcal Infections; Staphylococcus aureus | 2023 |
Targeting fibrotic signaling pathways by EGCG as a therapeutic strategy for uterine fibroids.
Topics: beta Catenin; Catechin; Fibrosis; Humans; Leiomyoma; Proto-Oncogene Proteins c-akt; Signal Transduction | 2023 |
Suppression of the excitability of rat nociceptive secondary sensory neurons following local administration of the Phytochemical, (-)-Epigallocatechin-3-gallate.
Topics: Action Potentials; Anesthetics, Local; Animals; Catechin; Lidocaine; Nociception; Phytochemicals; Rats; Rats, Wistar; Sensory Receptor Cells | 2023 |
Mitochondrial targets exploration of epigallocatechin gallate and theaflavin in regards to differences in stress protection under different temperatures.
Topics: Adenosine Triphosphate; Antioxidants; Catechin; Mitochondria; Temperature | 2023 |
Epigallocatechin gallate alleviates mono-2-ethylhexyl phthalate-induced male germ cell pyroptosis by inhibiting the ROS/mTOR/NLRP3 pathway.
Topics: Catechin; Heme Oxygenase-1; Humans; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Reactive Oxygen Species; TOR Serine-Threonine Kinases | 2023 |
Hormetic effects of EGC and EGCG on CES1 activity and its rescue from oxidative stress in rat liver S9.
Topics: Animals; Carboxylic Ester Hydrolases; Catechin; Enalapril; Humans; Liver; Oxidative Stress; Rats | 2023 |
Molecular mechanisms underlying the epigallocatechin-3-gallate-mediated inhibition of oral squamous cell carcinogenesis.
Topics: Carcinogenesis; Catechin; Cell Line, Tumor; Epithelial Cells; Humans; Mouth Neoplasms; Oral Submucous Fibrosis; Signal Transduction | 2023 |
Effects of epigallocatechin gallate, caffeine, and their combination on fat accumulation in high-glucose diet-fed Caenorhabditis elegans.
Topics: Animals; Caenorhabditis elegans; Caffeine; Catechin; Diet; Glucose; Tea; Triglycerides | 2023 |
Glazes induced degradation of tea catechins.
Topics: Catalysis; Catechin; Humans; Oxides; Tea | 2023 |
Molecular insights into α-glucosidase inhibition and antiglycation properties affected by the galloyl moiety in (-)-epigallocatechin-3-gallate.
Topics: alpha-Glucosidases; Catechin; Molecular Docking Simulation; Polyphenols; Spectrum Analysis; Tea | 2023 |
How oxidized EGCG remodels α-synuclein fibrils into non-toxic aggregates: insights from computational simulations.
Topics: alpha-Synuclein; Amyloid; Amyloidogenic Proteins; Catechin; Humans; Parkinson Disease; Protein Aggregates | 2023 |
EGCG attenuates METH self-administration and reinstatement of METH seeking in mice.
Topics: Animals; Ascorbic Acid; Catechin; Drug-Seeking Behavior; Methamphetamine; Mice; Reinforcement Schedule; Self Administration | 2023 |
NADPH oxidase 1: A target in the capacity of dimeric ECG and EGCG procyanidins to inhibit colorectal cancer cell invasion.
Topics: Caco-2 Cells; Catechin; Cell Line, Tumor; Colorectal Neoplasms; Electrocardiography; Epidermal Growth Factor; ErbB Receptors; Humans; Matrix Metalloproteinase 2; NADPH Oxidase 1; Neoplasm Invasiveness; Proanthocyanidins | 2023 |
(-)-Epigallocatechin-3-gallate induced apoptosis by dissociation of c-FLIP/Ku70 complex in gastric cancer cells.
Topics: Apoptosis; CASP8 and FADD-Like Apoptosis Regulating Protein; Catechin; Cell Line, Tumor; Cell Proliferation; Humans; Stomach Neoplasms | 2023 |
Zeolites with Divalent Ions as Carriers in the Delivery of Epigallocatechin Gallate.
Topics: Catechin; Drug Carriers; Drug Delivery Systems; Zeolites | 2023 |
EGCG attenuate EGF triggered matrix abundance and migration in HPV positive and HPV negative cervical cancer cells.
Topics: Catechin; Epidermal Growth Factor; Female; Humans; Matrix Metalloproteinase 2; Papillomavirus Infections; Tumor Microenvironment; Uterine Cervical Neoplasms | 2023 |
EGCG attenuated acute myocardial infarction by inhibiting ferroptosis via miR-450b-5p/ACSL4 axis.
Topics: Animals; Catechin; Disease Models, Animal; Mice; MicroRNAs; Myocardial Infarction; Myocardial Ischemia | 2023 |
Antibacterial efficacy of epigallocatechin-3-gallate cross-linked small intestinal submucosa guided bone regeneration membrane.
Topics: Anti-Bacterial Agents; Bone Regeneration; Catechin; Escherichia coli; Osteogenesis | 2023 |
The anti-cancer effect of epigallocatechin-3-O-gallate against multiple myeloma cells is potentiated by 5,7-dimethoxyflavone.
Topics: Apoptosis; Catechin; Cell Line, Tumor; Humans; Multiple Myeloma | 2023 |
Gallation and B-Ring Dihydroxylation Increase Green Tea Catechin Residence Time in Plasma by Differentially Affecting Tissue-Specific Trafficking: Compartmental Model of Catechin Kinetics in Healthy Adults.
Topics: Adult; Antioxidants; Biological Products; Catechin; Epidemiological Models; Humans; Kinetics; Plasma | 2023 |
Lutein combined with EGCG improved retinitis pigmentosa against
Topics: Animals; Catechin; Lutein; Methylnitrosourea; Mice; Retina; Retinitis Pigmentosa | 2023 |
Waxy maize starch incorporated (-)-epigallocatechin-3-gallate can stabilize emulsion gel and improve antioxidant activity.
Topics: Amylopectin; Antioxidants; Catechin; Emulsions; Hydrogels; Zea mays | 2023 |
Epigallocatechin gallate (EGCG) alleviates the inflammatory response and recovers oral microbiota in acetic acid-induced oral inflammation mice.
Topics: Acetic Acid; Animals; Catechin; Cytokines; Humans; Inflammation; Mice; Microbiota; Tea | 2023 |
Encapsulation of (-)-epigallocatechin gallate (EGCG) within phospholipid-based nanovesicles using W/O emulsion-transfer methods: Masking bitterness and delaying release of EGCG.
Topics: Catechin; Emulsions; Phospholipids; Taste; Tea | 2024 |
The Green Tea Polyphenol Epigallocatechin-Gallate (EGCG) Interferes with Microcin E492 Amyloid Formation.
Topics: Amyloid; Amyloidogenic Proteins; Catechin; Polyphenols; Tea | 2023 |
Assessing the Protective Role of Epigallocatechin Gallate (EGCG) against Water-Pipe Smoke-Induced Toxicity: A Comparative Study on Gene Expression and Histopathology.
Topics: Animals; Antioxidants; Catechin; Gene Expression; Inflammation; Mice; Oxidative Stress; Superoxide Dismutase; Water Pipe Smoking | 2023 |
Separation and antioxidant activities of new acetylated EGCG compounds.
Topics: Antioxidants; Catechin; Hydroxyl Radical; Superoxides | 2023 |