Page last updated: 2024-08-26

catalpol and iridoids

catalpol has been researched along with iridoids in 64 studies

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.56)18.7374
1990's5 (7.81)18.2507
2000's43 (67.19)29.6817
2010's13 (20.31)24.3611
2020's2 (3.13)2.80

Authors

AuthorsStudies
Du, H; Liu, F; Liu, G; Zhao, X1
Cubillo, L; Fernández, B; Martín, ML; Ortiz de Urbina, AV; San Román, L1
Asano, T; Honda, S; Kubo, M; Matsuda, H; Yutani, S1
Chiba, K; Mohri, T; Yamazaki, M1
Bernays, EA; Chapman, RF; Singer, MS1
Hartonen, K; Riekkola, ML; Sirén, H; Suomi, J1
Bian, B; Wang, H; Wang, T; Yang, J1
Jussila, M; Riekkola, ML; Suomi, J; Wiedmer, SK1
Nishibe, S; Tamura, Y1
Akamanchi, KG; Narayanan, P1
Cai, B; Guo, S; Pan, Y; Wang, H; Yin, F1
Li, XE; Yang, JS; Yang, SL1
BACON, JS; DUFF, RB; FARMER, VC; FORRESTER, AR; MUNDIE, CM; RUSSELL, JD1
Bowers, MD1
An, LJ; Bao, YM; Jiang, B; Liu, JH1
Ayub, MJ; Borkowski, EJ; Ciuffo, G; García, M; Giordano, OS; Pungitore, CR; Sosa, ME; Tonn, CE1
Biere, A; Marak, HB; van Damme, JM1
Dugassa-Gobena, D; Scheu, S; Wurst, S1
Bai, XM; Fu, YR; Guo, CY; Wang, ZB; Zhang, WM1
An, LJ; Bao, YM; Duan, YL; Li, DQ; Liu, CP; Liu, Y1
Bowers, MD; Fuchs, A1
Ayub, MJ; Borkowski, EJ; Ciuffo, GM; Pungitore, CR; Tonn, CE1
An, LJ; Bao, YM; Hu, B; Li, DQ; Li, Y; Liu, Y1
Baez, EG; Gutierrez, RM; Martinez, FM; Solis, RV1
An, LJ; Bao, YM; Li, DQ; Li, Y; Liu, Y; Wang, CF1
An, LJ; Chen, J; Duan, YL; Jiang, B; Jiang, L; Tian, YY1
An, LJ; Bao, YM; He, QJ; Liu, J; Liu, YX; Wang, HX; Zou, W1
An, LJ; Bao, YM; Jiang, B; Tian, YY1
An, LJ; Hao, S; Jiang, B; Li, ZB; Zhang, XL1
An, LJ; Duan, YL; Jiang, B; Li, YC; Wang, Z1
Dong, QT; Liu, YF; Wen, XS; Zhao, Y1
Chang-soo, Y; Je-Hyun, L; Ju-hee, O; Liu, XQ; Zhu, MF1
Luo, Y; Wan, D; Xie, P; Xu, XY; Zhu, HF1
An, L; Bao, Y; Jiang, B; Wang, J; Zhang, A; Zhang, X1
Bi, J; Jiang, B; Zhang, H; Zhang, XL1
An, LJ; Bao, YM; Jiang, B; Wang, JY; Zhang, XL1
An, LJ; Bi, J; Jiang, B; Lei, C; Liu, JH; Zhang, XL1
An, LJ; Bi, J; Chen, L; Guo, L; Hao, S; Jiang, B; Wang, XB1
An, L; Bao, Y; Bi, J; Hao, S; Jiang, B; Zhang, A; Zhang, X1
Li, XE; Qi, JJ; Wang, SH; Zhou, LL1
Lee, HK; Lee, HS; Oh, SR; Park, EJ1
Bennett, AE; Bever, JD; Deane Bowers, M1
Fontana, A; Gershenzon, J; Hempel, S; Reichelt, M; Unsicker, SB1
Hu, Y; Liu, Q; Liu, S; Wang, Z; Xia, Z; Zhang, R1
Gu, Y; Liu, C; Lu, R; Si, D1
Hu, B; Li, DQ; Wang, CF; Xue, HY1
Chen, G; He, Y; Li, W; Li, Z; Xu, X; Zhu, H1
Liu, Y; Wei, L; Xue, B; Zhang, Z1
Davitashvili, DT; Gegenava, LG; Museridze, DP; Sanikidze, TV; Svanidze, IK1
Hu, Y; Ke, Z; Wang, Z; Xia, Z; Xiong, Z; Xu, G; Yong, Y1
An, L; Liu, W; Niu, X; Zhang, X1
Wan, D; Zhang, F; Zhu, H1
Daranas, AH; García, C; León, LG; Martín, VS; Montero, JC; Padrón, JM; Pandiella, A; Pungitore, CR; Ríos-Luci, C; Tonn, CE1
Cheng, JT; Hsu, FL; Huang, WJ; Lin, MH; Niu, HS1
Hong, JL; Qin, MJ; Qin, XY; Shu, P; Wang, Q; Wu, G1
Fan, H; Gong, N; Ma, AN; Wang, YX; Xiao, Q1
Ji, XQ; Li, XE; Liao, DQ; Qi, JJ; Sun, P1
Du, L; Duan, JA; Guo, J; Jiang, S; Liu, P; Qian, D; Shang, EX; Su, SL; Tao, J; Zhao, M1
Chung, HY; Kang, U; Kil, YS; Kim, SM; Seo, EK1
Abdel-Kader, M; Al-Massarani, S; Al-Rehaily, A; Ati, H; Basudan, O; Becnel, J; El-Gamal, A; Fawzy, G; Tabanca, N1
Duan, JA; Jiang, S; Tao, JH; Xu, BH; Zhang, W; Zhao, M1
Sun, HJ; Xu, CY; Zhang, H; Zhang, YK1
Chen, J; Chen, Y; Du, Q; Fu, Y; Jiang, M; Jiao, N; Liu, L; Sun, J; Wu, H; Xu, H; Zhu, Y1
Chen, H; Deng, M; Li, X; Liu, K; Shi, M; Xie, L; Zhang, X1

Reviews

3 review(s) available for catalpol and iridoids

ArticleYear
[Advances in research on pharmacodynamics and chemical conversion of catalpol].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:12

    Topics: Animals; Antineoplastic Agents, Phytogenic; Drugs, Chinese Herbal; Glucosides; Humans; Hypoglycemic Agents; Iridoid Glucosides; Iridoids; Neuroprotective Agents; Plants, Medicinal; Rehmannia; Technology, Pharmaceutical

2007
[Progress in studies of pharmacological action and mechanisms of catalpol on brain diease].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2009, Volume: 34, Issue:23

    Topics: Animals; Brain Diseases; Drugs, Chinese Herbal; Gene Expression; Glucosides; Humans; Iridoid Glucosides; Iridoids; Rehmannia

2009
Therapeutic potential of catalpol and geniposide in Alzheimer's and Parkinson's diseases: A snapshot of their underlying mechanisms.
    Brain research bulletin, 2021, Volume: 174

    Topics: Alzheimer Disease; Animals; Antiparkinson Agents; Drugs, Chinese Herbal; Gardenia; Humans; Iridoid Glucosides; Iridoids; Medicine, Chinese Traditional; Parkinson Disease; Rehmannia

2021

Other Studies

61 other study(ies) available for catalpol and iridoids

ArticleYear
[Quality of dihuang (Rehmannia spp.)].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1992, Volume: 17, Issue:6

    Topics: Calcium; Carbohydrates; Drugs, Chinese Herbal; Glucosides; Iridoid Glucosides; Iridoids; Phosphorus; Pyrans; Quality Control; Trace Elements

1992
In vitro antispasmodic activity of peracetylated penstemonoside, aucubin and catalpol.
    Planta medica, 1994, Volume: 60, Issue:6

    Topics: Acetylation; Animals; Female; Glucosides; In Vitro Techniques; Iridoid Glucosides; Iridoids; Male; Parasympatholytics; Plants; Pyrans; Rats; Uterus; Vas Deferens

1994
[Studies on Rehmanniae radix. III. The relation between changes of constituents and improvable effects on hemorheology with the processing of roots of Rehmannia glutinosa].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1996, Volume: 116, Issue:2

    Topics: Adenosine Triphosphate; Animals; Carbohydrates; Drugs, Chinese Herbal; Erythrocyte Aggregation; Erythrocyte Deformability; Erythrocytes; Fibrinolysis; Glucosides; Iridoid Glucosides; Iridoids; Male; Pyrans; Rabbits; Rats; Rats, Wistar

1996
Neuritogenic effect of natural iridoid compounds on PC12h cells and its possible relation to signaling protein kinases.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:6

    Topics: Animals; beta-Glucosidase; Calcium; Glucosides; Hydrolysis; Iridoid Glucosides; Iridoid Glycosides; Iridoids; Neurites; Neurons; PC12 Cells; Protein Kinase Inhibitors; Pyrans; Rats; Signal Transduction

1996
Sensitivity to chemically diverse phagostimulants in a single gustatory neuron of a polyphagous caterpillar.
    Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, 2000, Volume: 186, Issue:1

    Topics: Action Potentials; Amino Acids; Animals; Behavior, Animal; Carbohydrates; Electrophysiology; Feeding Behavior; Glucosides; Iridoid Glucosides; Iridoids; Moths; Neurons, Afferent; Pyrans; Serine; Taste

2000
Extraction of iridoid glycosides and their determination by micellar electrokinetic capillary chromatography.
    Journal of chromatography. A, 2000, Jan-28, Volume: 868, Issue:1

    Topics: Chromatography, Micellar Electrokinetic Capillary; Glucosides; Hot Temperature; Iridoid Glucosides; Iridoids; Plant Leaves; Pressure; Pyrans; Solvents

2000
[Catalpol content changes in Rehmannia glutinosa (Gaertn.) Libosch. under certain conditions].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1997, Volume: 22, Issue:7

    Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Glucosides; Hot Temperature; Iridoid Glucosides; Iridoids; Magnoliopsida; Plants, Medicinal; Pyrans; Technology, Pharmaceutical

1997
Determination of iridoid glycosides by micellar electrokinetic capillary chromatography-mass spectrometry with use of the partial filling technique.
    Electrophoresis, 2001, Volume: 22, Issue:12

    Topics: Chromatography, Micellar Electrokinetic Capillary; Glucosides; Hydrogen-Ion Concentration; Iridoid Glucosides; Iridoid Glycosides; Iridoids; Mass Spectrometry; Molecular Structure; Molecular Weight; Plantago; Plants, Medicinal; Pyrans; Scrophulariaceae; Species Specificity; Spectrophotometry, Ultraviolet; Valerianaceae

2001
Changes in the concentrations of bioactive compounds in plantain leaves.
    Journal of agricultural and food chemistry, 2002, Apr-24, Volume: 50, Issue:9

    Topics: Chromatography, High Pressure Liquid; Climate; Desiccation; Glucosides; Iridoid Glucosides; Iridoids; Phenols; Plant Leaves; Plantago; Pyrans; Seasons

2002
Colorimetric estimation of total iridoid content of Picrorhiza kurrooa.
    Journal of Asian natural products research, 2003, Volume: 5, Issue:2

    Topics: Colorimetry; Glucosides; Glycine; India; Iridoid Glucosides; Iridoids; Picrorhiza; Plant Roots

2003
[Study on chitosan clarification refining the decoction of jiangtangtongmai by homogenous design method].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2003, Volume: 26, Issue:2

    Topics: Alcohols; Chitin; Chitosan; Drug Combinations; Drugs, Chinese Herbal; Glucosides; Hypoglycemic Agents; Iridoid Glucosides; Iridoids; Plants, Medicinal; Rehmannia; Rosa; Technology, Pharmaceutical

2003
[Comparison and correlative analysis on characters of Rehmannia glutinosa Libosch. Varieties].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2001, Volume: 23, Issue:6

    Topics: Glucosides; Iridoid Glucosides; Iridoids; Plant Leaves; Plant Tubers; Rehmannia

2001
CATALPOL AND METHYLCATALPOL: NATURALLY OCCURRING GLYCOSIDES IN PLANTAGO AND BUDDLEIA SPECIES.
    The Biochemical journal, 1965, Volume: 96

    Topics: Buddleja; Chemistry, Pharmaceutical; Glucosides; Glycosides; Iridoid Glucosides; Iridoids; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Plant Leaves; Plantago; Plants, Medicinal; Research; Spectrum Analysis

1965
Hostplant suitability and defensive chemistry of the Catalpa sphinx, Ceratomia catalpae.
    Journal of chemical ecology, 2003, Volume: 29, Issue:10

    Topics: Adaptation, Physiological; Age Factors; Animals; Chromatography, Gas; Glucosides; Hemolymph; Host-Parasite Interactions; Iridoid Glucosides; Iridoids; Larva; Moths; Plants, Edible; Predatory Behavior

2003
Catalpol inhibits apoptosis in hydrogen peroxide-induced PC12 cells by preventing cytochrome c release and inactivating of caspase cascade.
    Toxicon : official journal of the International Society on Toxinology, 2004, Volume: 43, Issue:1

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspases; Cytochromes c; Drugs, Chinese Herbal; Gene Expression Regulation; Genes, bcl-2; Glucosides; Hydrogen Peroxide; Iridoid Glucosides; Iridoids; PC12 Cells; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats

2004
Iridoids as allelochemicals and DNA polymerase inhibitors.
    Journal of natural products, 2004, Volume: 67, Issue:3

    Topics: Animals; Enzyme Inhibitors; Glucosides; Insect Control; Iridoid Glucosides; Iridoid Glycosides; Iridoids; Larva; Models, Molecular; Molecular Structure; Nucleic Acid Synthesis Inhibitors; Pyrans; Tribolium

2004
Plant chemical defense against herbivores and pathogens: generalized defense or trade-offs?
    Oecologia, 2004, Volume: 140, Issue:3

    Topics: Adaptation, Physiological; Animals; Biological Evolution; Feeding Behavior; Fungi; Glucosides; Iridoid Glucosides; Iridoids; Plantago; Plants, Edible; Spodoptera

2004
Earthworms and litter distribution affect plant-defensive chemistry.
    Journal of chemical ecology, 2004, Volume: 30, Issue:4

    Topics: Animals; Aphids; Glucosides; Iridoid Glucosides; Iridoids; Nitrogen; Nitrogen Radioisotopes; Oligochaeta; Phytosterols; Plant Leaves; Plant Shoots; Plantago; Soil

2004
[Determination of catalpol in dried rehmannia root and Taohong Siwu Decoction with high performance liquid chromatography].
    Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2004, Volume: 2, Issue:2

    Topics: Chromatography, High Pressure Liquid; Glucosides; Iridoid Glucosides; Iridoids; Medicine, Chinese Traditional; Rehmannia

2004
Neuroprotection of catalpol in transient global ischemia in gerbils.
    Neuroscience research, 2004, Volume: 50, Issue:2

    Topics: Animals; Apoptosis; Behavior, Animal; Brain Ischemia; Disease Models, Animal; Female; Gerbillinae; Glucosides; Glutathione Peroxidase; Hippocampus; In Situ Nick-End Labeling; Iridoid Glucosides; Iridoids; Lipid Peroxides; Male; Maze Learning; Neurons; Neuroprotective Agents; Nitric Oxide Synthase

2004
Patterns of iridoid glycoside production and induction in Plantago lanceolata and the importance of plant age.
    Journal of chemical ecology, 2004, Volume: 30, Issue:9

    Topics: Glucosides; Iridoid Glucosides; Iridoids; Plant Leaves; Plantago; Time Factors

2004
Inhibition of Taq DNA polymerase by catalpol.
    Cellular and molecular biology (Noisy-le-Grand, France), 2004, Volume: 50, Issue:6

    Topics: Binding Sites; DNA; Glucosides; Iridoid Glucosides; Iridoids; Molecular Structure; Nucleotides; Polymerase Chain Reaction; Taq Polymerase

2004
Catalpol prevents the loss of CA1 hippocampal neurons and reduces working errors in gerbils after ischemia-reperfusion injury.
    Toxicon : official journal of the International Society on Toxinology, 2005, Dec-15, Volume: 46, Issue:8

    Topics: Analysis of Variance; Animals; Behavioral Symptoms; Dose-Response Relationship, Drug; Gerbillinae; Glucosides; Hippocampus; Iridoid Glucosides; Iridoids; Neurons; Neuroprotective Agents; Reperfusion Injury; Time Factors

2005
Effect on capillary permeability in rabbits of iridoids from Buddleia scordioides.
    Phytotherapy research : PTR, 2006, Volume: 20, Issue:7

    Topics: Animals; Buddleja; Capillaries; Glucosides; Hydroxyethylrutoside; Iridoid Glucosides; Iridoids; Male; Permeability; Rabbits; Skin; Vasoconstrictor Agents

2006
Catalpol modulates the expressions of Bcl-2 and Bax and attenuates apoptosis in gerbils after ischemic injury.
    Brain research, 2006, Oct-18, Volume: 1115, Issue:1

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain Infarction; Brain Ischemia; Disease Models, Animal; Drug Administration Schedule; Drugs, Chinese Herbal; Female; Gene Expression Regulation, Enzymologic; Gerbillinae; Glucosides; Hippocampus; Immunohistochemistry; In Situ Nick-End Labeling; Iridoid Glucosides; Iridoids; Male; Nerve Degeneration; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Reperfusion Injury; Treatment Outcome

2006
Catalpol protects dopaminergic neurons from LPS-induced neurotoxicity in mesencephalic neuron-glia cultures.
    Life sciences, 2006, Dec-23, Volume: 80, Issue:3

    Topics: Animals; Cells, Cultured; Coculture Techniques; Dopamine; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glucosides; Inflammation; Iridoid Glucosides; Iridoids; Lipopolysaccharides; Mesencephalon; Mice; Nerve Degeneration; Neurodegenerative Diseases; Neuroglia; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type II; Reactive Oxygen Species; Tumor Necrosis Factor-alpha

2006
Catalpol increases hippocampal neuroplasticity and up-regulates PKC and BDNF in the aged rats.
    Brain research, 2006, Dec-06, Volume: 1123, Issue:1

    Topics: Aging; Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Drugs, Chinese Herbal; GAP-43 Protein; Glucosides; Hippocampus; Iridoid Glucosides; Iridoids; Male; Neuronal Plasticity; Neuroprotective Agents; Protein Kinase C; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Synaptophysin; Up-Regulation

2006
Neuroprotective effect of catalpol against MPP(+)-induced oxidative stress in mesencephalic neurons.
    European journal of pharmacology, 2007, Jul-30, Volume: 568, Issue:1-3

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Glucosides; Glutathione Peroxidase; Iridoid Glucosides; Iridoids; Membrane Potential, Mitochondrial; Mesencephalon; Mice; Neurons; Neuroprotective Agents; Oxidative Stress; Superoxide Dismutase

2007
Catalpol ameliorates cognition deficits and attenuates oxidative damage in the brain of senescent mice induced by D-galactose.
    Pharmacology, biochemistry, and behavior, 2007, Volume: 88, Issue:1

    Topics: Aging; Animals; Brain Chemistry; Ca(2+) Mg(2+)-ATPase; Cerebral Cortex; Cognition Disorders; Female; Galactose; Glucosides; Glutathione Peroxidase; Indicators and Reagents; Iridoid Glucosides; Iridoids; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; Mice; Oxidative Stress; Plant Roots; Rehmannia; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase

2007
Catalpol protects rat pheochromocytoma cells against oxygen and glucose deprivation-induced injury.
    Neurological research, 2008, Volume: 30, Issue:1

    Topics: Animals; Apoptosis; Caspase 3; Cell Count; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glucose; Glucosides; Glutathione Peroxidase; Hypoxia; Iridoid Glucosides; Iridoids; Membrane Potential, Mitochondrial; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Superoxide Dismutase

2008
[Effect of concentration of catalpol and 5-hydroxymethyl-2-furaldehyde from processing of Rehmanniae Radix].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:12

    Topics: Chromatography, High Pressure Liquid; Ethanol; Furaldehyde; Glucosides; Hot Temperature; Iridoid Glucosides; Iridoids; Plant Tubers; Plants, Medicinal; Rehmannia; Technology, Pharmaceutical

2007
[Study of catalpol promoting axonal growth for cultured cortical neurons from rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:17

    Topics: Animals; Animals, Newborn; Axons; Cell Survival; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glucosides; Iridoid Glucosides; Iridoids; Neurons; Neuroprotective Agents; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Rehmannia

2007
Further pharmacological evidence of the neuroprotective effect of catalpol from Rehmannia glutinosa.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2008, Volume: 15, Issue:6-7

    Topics: Aging; Animals; Ca(2+) Mg(2+)-ATPase; Creatine Kinase; Energy Metabolism; Galactose; Glucosides; Glutamate-Ammonia Ligase; Glutathione; Iridoid Glucosides; Iridoids; Lipid Peroxidation; Liver; Malondialdehyde; Mice; Mitochondria, Liver; Neuroprotective Agents; Oxidative Stress; Oxidoreductases; Rehmannia; Sodium-Potassium-Exchanging ATPase; Spleen

2008
Neuroprotective activities of catalpol on MPP+/MPTP-induced neurotoxicity.
    Neurological research, 2008, Volume: 30, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Brain; Cell Survival; Dopamine; Dose-Response Relationship, Drug; Glucosides; Iridoid Glucosides; Iridoids; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; PC12 Cells; Rats; Tetrazolium Salts; Thiazoles; Time Factors; Tyrosine 3-Monooxygenase

2008
d-galactose administration induces memory loss and energy metabolism disturbance in mice: protective effects of catalpol.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:8

    Topics: Aging; Animals; Avoidance Learning; Brain; Brain Chemistry; Cerebral Cortex; Cognition; Creatine Kinase; Energy Metabolism; Female; Galactose; Glucosides; Glutathione; Glutathione Transferase; Hippocampus; Indicators and Reagents; Iridoid Glucosides; Iridoids; L-Lactate Dehydrogenase; Male; Memory Disorders; Mice; Motor Activity; Plant Roots; Rehmannia

2008
Protective effects of catalpol against H2O2-induced oxidative stress in astrocytes primary cultures.
    Neuroscience letters, 2008, Sep-19, Volume: 442, Issue:3

    Topics: Animals; Antioxidants; Astrocytes; Catalase; Cell Survival; Cells, Cultured; Glucosides; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Hydrogen Peroxide; Iridoid Glucosides; Iridoids; Mice; Oxidants; Oxidative Stress; Reactive Oxygen Species

2008
Catalpol protects mesencephalic neurons against MPTP induced neurotoxicity via attenuation of mitochondrial dysfunction and MAO-B activity.
    Toxicology in vitro : an international journal published in association with BIBRA, 2008, Volume: 22, Issue:8

    Topics: Animals; Astrocytes; Calcium; Cells, Cultured; Glucosides; Iridoid Glucosides; Iridoids; Membrane Potential, Mitochondrial; Mesencephalon; Mice; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Monoamine Oxidase; MPTP Poisoning; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Reactive Oxygen Species; Rehmannia

2008
Effects of catalpol on mitochondrial function and working memory in mice after lipopolysaccharide-induced acute systemic inflammation.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2009, Volume: 61, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Brain; Glucosides; Inflammation; Iridoid Glucosides; Iridoids; Lipopolysaccharides; Maze Learning; Memory; Mice; Mitochondria; NF-kappa B

2009
[Comparative analysis of character on germplasm resources of Rehmannia glutinosa].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:18

    Topics: Chromatography, High Pressure Liquid; Glucosides; Iridoid Glucosides; Iridoids; Plant Leaves; Plants, Medicinal; Rehmannia

2008
Liquid chromatography-mass spectrometry for the simultaneous determination of the catalpol-related iridoid glucosides, verproside, isovanilloylcatalpol, catalposide and 6-O-veratroyl catalpol in rat plasma.
    Biomedical chromatography : BMC, 2009, Volume: 23, Issue:9

    Topics: Animals; Area Under Curve; Calibration; Chromatography, Liquid; Glucosides; Iridoid Glucosides; Iridoids; Least-Squares Analysis; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2009
Arbuscular mycorrhizal fungal species suppress inducible plant responses and alter defensive strategies following herbivory.
    Oecologia, 2009, Volume: 160, Issue:4

    Topics: Analysis of Variance; Animals; Butterflies; Feeding Behavior; Glomeromycota; Glucosides; Iridoid Glucosides; Iridoids; Larva; Mycorrhizae; North Carolina; Plantago

2009
The effects of arbuscular mycorrhizal fungi on direct and indirect defense metabolites of Plantago lanceolata L.
    Journal of chemical ecology, 2009, Volume: 35, Issue:7

    Topics: Acetates; Animals; Glucosides; Host-Parasite Interactions; Iridoid Glucosides; Iridoids; Mycorrhizae; Plantago; Sesquiterpenes; Spodoptera; Symbiosis; Volatile Organic Compounds

2009
Catalpol ameliorates beta amyloid-induced degeneration of cholinergic neurons by elevating brain-derived neurotrophic factors.
    Neuroscience, 2009, Nov-10, Volume: 163, Issue:4

    Topics: Amyloid beta-Peptides; Animals; Brain; Brain-Derived Neurotrophic Factor; Cells, Cultured; Choline O-Acetyltransferase; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glucosides; Iridoid Glucosides; Iridoids; Learning; Memory; Mice; Mice, Inbred ICR; Neurites; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic

2009
Quantitation of catalpol in rat plasma by liquid chromatography/electrospray ionization tandem mass spectrometry and its pharmacokinetic study.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Nov-01, Volume: 877, Issue:29

    Topics: Animals; Chromatography, Liquid; Glucosides; Iridoid Glucosides; Iridoids; Rats; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2009
Oral supplementation of catalpol ameliorates diabetic encephalopathy in rats.
    Brain research, 2010, Jan-11, Volume: 1307

    Topics: Administration, Oral; Animals; Behavior, Animal; Blood Glucose; Body Weight; Catalase; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glucosides; Glutathione Peroxidase; In Situ Nick-End Labeling; Iridoid Glucosides; Iridoids; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; Nerve Growth Factor; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Time Factors

2010
[HPLC determination of catalpol in cerebrospinal fluid of rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2009, Volume: 34, Issue:13

    Topics: Animals; Chromatography, High Pressure Liquid; Glucosides; Iridoid Glucosides; Iridoids; Male; Random Allocation; Rats; Rats, Sprague-Dawley

2009
[Protective effects of catalpol against H2O2-induced oxidative damage in astrocytes].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2009, Volume: 34, Issue:15

    Topics: Animals; Astrocytes; Cell Survival; Cells, Cultured; Glucosides; Hydrogen Peroxide; Iridoid Glucosides; Iridoids; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley

2009
[Investigation of oxidative stress-induced alterations in the rat brain cortical cellular culture and their correction with vitamines E and C].
    Georgian medical news, 2009, Issue:177

    Topics: Animals; Ascorbic Acid; Brain; Brain Diseases; Drugs, Chinese Herbal; Glucosides; Iridoid Glucosides; Iridoids; Oxidative Stress; Rats; Vitamin E

2009
Catalpol attenuates MPTP induced neuronal degeneration of nigral-striatal dopaminergic pathway in mice through elevating glial cell derived neurotrophic factor in striatum.
    Neuroscience, 2010, Apr-28, Volume: 167, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Cells, Cultured; Chronic Disease; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Glial Cell Line-Derived Neurotrophic Factor; Glucosides; Iridoid Glucosides; Iridoids; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Motor Activity; Nerve Degeneration; Neural Pathways; Neurons; Neuroprotective Agents; Probenecid; Substantia Nigra

2010
Systemic administration of catalpol prevents D-galactose induced mitochondrial dysfunction in mice.
    Neuroscience letters, 2010, Apr-12, Volume: 473, Issue:3

    Topics: Animals; Cerebral Cortex; Electron Transport Complex I; Electron Transport Complex IV; Female; Galactose; Glucosides; Hippocampus; Iridoid Glucosides; Iridoids; Male; Membrane Potential, Mitochondrial; Mice; Mitochondria; Neuroprotective Agents; Nitric Oxide Synthase; Reactive Oxygen Species

2010
Enhancement of antiproliferative activity by molecular simplification of catalpol.
    Bioorganic & medicinal chemistry, 2010, Apr-01, Volume: 18, Issue:7

    Topics: Annexin A5; Antineoplastic Agents; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Glucosides; Humans; Iridoid Glucosides; Iridoids; Models, Molecular; Molecular Conformation; Structure-Activity Relationship

2010
Antihyperglycemic effect of catalpol in streptozotocin-induced diabetic rats.
    Journal of natural products, 2010, Jun-25, Volume: 73, Issue:6

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucosides; Glycogen; Hepatocytes; Hypoglycemic Agents; Insulin; Iridoid Glucosides; Iridoids; Male; Molecular Structure; Muscle, Skeletal; Plant Roots; Plants, Medicinal; Rats; Rats, Wistar; Rehmannia; Taiwan

2010
Analysis of catalpol derivatives by characteristic neutral losses using liquid chromatography combined with electrospray ionization multistage and time-of-flight mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2010, Sep-15, Volume: 24, Issue:17

    Topics: Chromatography, Liquid; Iridoid Glucosides; Iridoids; Spectrometry, Mass, Electrospray Ionization; Veronica

2010
Geniposide and its iridoid analogs exhibit antinociception by acting at the spinal GLP-1 receptors.
    Neuropharmacology, 2014, Volume: 84

    Topics: Analgesics; Animals; Central Nervous System Agents; Exenatide; Formaldehyde; Glucagon-Like Peptide-1 Receptor; HEK293 Cells; Heterocyclic Compounds, 3-Ring; Humans; Iridoid Glucosides; Iridoids; Male; Mice; Nociception; PC12 Cells; Peptide Fragments; Peptides; Rats; Rats, Wistar; Receptors, Glucagon; Spinal Cord; Venoms

2014
[Study on distribution and dynamic accumulation of catalpol and total iridoid in fresh Rehmannia glutinosa].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014, Volume: 39, Issue:3

    Topics: Iridoid Glucosides; Iridoids; Plant Roots; Rehmannia; Seasons; Water

2014
Simultaneous determination of loganin, morroniside, catalpol and acteoside in normal and chronic kidney disease rat plasma by UPLC-MS for investigating the pharmacokinetics of Rehmannia glutinosa and Cornus officinalis Sieb drug pair extract.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016, Jan-15, Volume: 1009-1010

    Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Cornus; Drugs, Chinese Herbal; Glucosides; Glycosides; Iridoid Glucosides; Iridoids; Limit of Detection; Male; Mass Spectrometry; Phenols; Rats; Rats, Sprague-Dawley; Rehmannia; Renal Insufficiency, Chronic

2016
Peroxynitrite-Scavenging Glycosides from the Stem Bark of Catalpa ovata.
    Journal of natural products, 2017, 08-25, Volume: 80, Issue:8

    Topics: Bignoniaceae; Furans; Glucosides; Glycosides; Inhibitory Concentration 50; Iridoid Glucosides; Iridoids; Lignans; Molecular Structure; Peroxynitrous Acid; Plant Stems

2017
Chemical Composition of Buddleja polystachya Aerial Parts and its Bioactivity against Aedes aegypti.
    Natural product research, 2018, Volume: 32, Issue:23

    Topics: Aedes; Animals; Buddleja; Female; Flavonoids; Glycosides; Insecticides; Iridoid Glucosides; Iridoids; Male; Plant Components, Aerial; Plant Extracts

2018
UPLC-Q-TOF/MS-based metabolic profiling comparison of four major bioactive components in normal and CKD rat plasma, urine and feces following oral administration of Cornus officinalis Sieb and Rehmannia glutinosa Libosch herb couple extract.
    Journal of pharmaceutical and biomedical analysis, 2018, Nov-30, Volume: 161

    Topics: Administration, Oral; Animals; Case-Control Studies; Chromatography, High Pressure Liquid; Cornus; Feces; Glucosides; Glycosides; Iridoid Glucosides; Iridoids; Male; Phenols; Plant Extracts; Rats; Rehmannia; Renal Insufficiency, Chronic; Tandem Mass Spectrometry

2018
[Mechanism of inhibitory effect of catalpol on TNF-α induced HAECs cell damage].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2019, Volume: 44, Issue:4

    Topics: Humans; Iridoid Glucosides; Iridoids; Oxidative Stress; Reactive Oxygen Species; Tumor Necrosis Factor-alpha

2019
Loganin and catalpol exert cooperative ameliorating effects on podocyte apoptosis upon diabetic nephropathy by targeting AGEs-RAGE signaling.
    Life sciences, 2020, Jul-01, Volume: 252

    Topics: Animals; Apoptosis; Diabetic Nephropathies; Drug Therapy, Combination; Glycation End Products, Advanced; Iridoid Glucosides; Iridoids; Male; Mice; Mice, Inbred C57BL; NADPH Oxidase 4; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Podocytes; Receptor for Advanced Glycation End Products; Signal Transduction

2020