Page last updated: 2024-09-04

caseins and methotrexate

caseins has been researched along with methotrexate in 6 studies

Compound Research Comparison

Studies
(caseins)
Trials
(caseins)
Recent Studies (post-2010)
(caseins)
Studies
(methotrexate)
Trials
(methotrexate)
Recent Studies (post-2010) (methotrexate)
16,8635614,17041,5935,66611,969

Protein Interaction Comparison

ProteinTaxonomycaseins (IC50)methotrexate (IC50)
Thymidylate synthase Escherichia coli1.8
nuclear receptor coactivator 3 isoform aHomo sapiens (human)0.211
Toll-like receptor 4Homo sapiens (human)1.04
Fatty-acid amide hydrolase 1Mus musculus (house mouse)0.08
Dihydrofolate reductaseHomo sapiens (human)0.0522
Dihydrofolate reductaseMus musculus (house mouse)0.0331
Dihydrofolate reductase Bos taurus (cattle)0.0348
Dihydrofolate reductaseGallus gallus (chicken)0.0545
Dihydrofolate reductaseEnterococcus faecium0.0014
Dihydrofolate reductaseLacticaseibacillus casei0.0138
Thymidylate synthaseHomo sapiens (human)0.343
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.0147
Thymidylate synthaseEscherichia coli K-120.0181
Dihydrofolate reductaseEscherichia coli K-120.1529
Bifunctional dihydrofolate reductase-thymidylate synthasePlasmodium falciparum K10.084
Folate receptor betaHomo sapiens (human)0.1585
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.0011
Cytochrome P450 11B1, mitochondrial Bos taurus (cattle)0.0012
Folate receptor alphaHomo sapiens (human)0.2263
Dihydrofolate reductasePneumocystis carinii0.0717
Histidine decarboxylaseRattus norvegicus (Norway rat)0.0014
Trifunctional purine biosynthetic protein adenosine-3Homo sapiens (human)0.01
Bifunctional purine biosynthesis protein ATICHomo sapiens (human)0.01
Delta-type opioid receptorRattus norvegicus (Norway rat)0.003
Mu-type opioid receptorRattus norvegicus (Norway rat)0.003
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.003
Reduced folate transporterHomo sapiens (human)0.012
Dihydrofolate reductaseMycobacterium tuberculosis H37Rv0.0174
Folylpolyglutamate synthase, mitochondrialHomo sapiens (human)3.2
Bifunctional dihydrofolate reductase-thymidylate synthaseToxoplasma gondii0.0547
Bifunctional dihydrofolate reductase-thymidylate synthaseTrypanosoma cruzi0.11
Dihydrofolate reductase Bacillus anthracis0.0136
Dihydrofolate reductaseRattus norvegicus (Norway rat)0.0047
Proton-coupled folate transporterHomo sapiens (human)0.1207

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's4 (66.67)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baker, DH; Funk, MA2
Hardt, F1
Chevreau, N; Funk-Archuleta, M1
Bathurst, IC; Foehr, MW; Funk-Archuleta, MA; Khazalpour, KM; Logvinova, AV; Pemberton, PA; Tomei, LD1
Ariyama, H; Baba, E; Harada, M; Kashiwabara, N; Mitsugi, K; Nakamura, M; Nakamura, T; Nakano, S; Tanaka, R1

Other Studies

6 other study(ies) available for caseins and methotrexate

ArticleYear
Effect of fiber, protein source and time of feeding on methotrexate toxicity in rats.
    The Journal of nutrition, 1991, Volume: 121, Issue:10

    Topics: Animals; Anorexia; Caseins; Diarrhea; Dietary Fiber; Dietary Proteins; Glycine max; Male; Methotrexate; Rats; Rats, Inbred Strains; Time Factors

1991
Effect of soy products on methotrexate toxicity in rats.
    The Journal of nutrition, 1991, Volume: 121, Issue:10

    Topics: Animals; Anorexia; Caseins; Diarrhea; Diet; Glycine max; Injections, Intraperitoneal; Intestines; Male; Methotrexate; Rats; Rats, Inbred Strains

1991
Acceleration of casein induced amyloidosis in mice by immunosuppressive agents.
    Acta pathologica et microbiologica Scandinavica. Section A, Pathology, 1971, Volume: 79, Issue:1

    Topics: Amyloid; Amyloidosis; Animals; Azathioprine; Busulfan; Caseins; Chloramphenicol; Cortisone; Dactinomycin; Daunorubicin; DNA; Female; Fluorouracil; Immunosuppressive Agents; Liver; Male; Mercaptopurine; Methotrexate; Mice; RNA; Spleen; Vinblastine

1971
Effect of enteral formulas on methotrexate toxicity.
    Nutrition and cancer, 1995, Volume: 23, Issue:2

    Topics: Animals; Caseins; Diarrhea; Dietary Fiber; Enteral Nutrition; Food, Formulated; Humans; Male; Methotrexate; Plant Proteins, Dietary; Rats; Rats, Sprague-Dawley; Soybean Proteins; Weight Loss

1995
Soy-derived antiapoptotic fractions protect gastrointestinal epithelium from damage caused by methotrexate treatment in the rat.
    Nutrition and cancer, 1999, Volume: 33, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Caseins; Gastrointestinal Neoplasms; Intestinal Mucosa; Male; Methotrexate; Mice; Rats; Rats, Sprague-Dawley; Soybean Proteins; Trypsin Inhibitors

1999
Protection against methotrexate toxicity by a soybean protein- and omega-3 fatty acid-containing diet: comparative study with a casein-containing diet.
    Oncology reports, 2004, Volume: 12, Issue:1

    Topics: Animals; Appetite; Body Weight; Caseins; Diet; Fatty Acids, Omega-3; Glycine max; Intestinal Mucosa; Male; Methotrexate; Mice; Microvilli; Rats; Rats, Sprague-Dawley; Soybean Proteins

2004