Page last updated: 2024-09-04

caseins and indomethacin

caseins has been researched along with indomethacin in 15 studies

Compound Research Comparison

Studies
(caseins)
Trials
(caseins)
Recent Studies (post-2010)
(caseins)
Studies
(indomethacin)
Trials
(indomethacin)
Recent Studies (post-2010) (indomethacin)
16,8635614,17029,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomycaseins (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19906 (40.00)18.7374
1990's2 (13.33)18.2507
2000's3 (20.00)29.6817
2010's3 (20.00)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Rillema, JA1
Clark, DA; Gu, XA; Miller, MJ; Zhang, XJ1
Ahmed, AM; Blachier, F; Lacroix, MC; Léger, C; Ollivier-Bousquet, M1
Hashida, R; Hattori, S; Hori, H; Kobayashi, S; Nagai, Y; Ohsawa, S; Shirota, H; Yoshimatsu, K1
Glants, RM; Iakovenko, AN; Liubinets, LA; Parobetskaia, IM1
Kimura, K; Matsunaga, Y; Ogawa, K; Otsuka, M; Sato, K; Tokuhara, S; Tsubura, E1
Houdebine, LM; Lacroix, MC1
Dietl, G; Ender, K; Löhrke, B; Viergutz, T; Wegner, J1
Banik, NL; Gantt-Wilford, G; Hogan, EL; Matzelle, D; Terry, E1
Anthony, FW; Brawley, L; Hanson, MA; Itoh, S; Poston, L; Wheeler, T1
Isobe, N; Oda, M; Suzuki, M; Tanabe, S1
Inagaki, M; Kanamaru, Y; Muranishi, H; Saito, S; Uchida, K; Yabe, T; Yamamoto, M; Yamashita, K1
Baba, Y; Inada, A; Oshima, T; Takahashi, H1
Benoit, B; Bessette, C; Bruno, J; Estienne, M; Ferrier, L; Léonil, J; Plaisancié, P; Sekkal, S; Théodorou, V1
Bahena-Delgado, AI; Cervantes-García, D; Córdova-Dávalos, LE; Jiménez, M; Martínez-Saldaña, MC; Ruiz-Esparza Palacios, V; Salinas, E; Sánchez-Alemán, E1

Other Studies

15 other study(ies) available for caseins and indomethacin

ArticleYear
Effects of prostaglandins on RNA and casein synthesis in mammary gland explants of mice.
    Endocrinology, 1976, Volume: 99, Issue:2

    Topics: Animals; Breast; Caseins; Female; In Vitro Techniques; Indomethacin; Mice; Pregnancy; Prolactin; Prostaglandins; Prostaglandins A; Prostaglandins E; Prostaglandins F; RNA; Time Factors; Uridine

1976
Acute intestinal injury induced by acetic acid and casein: prevention by intraluminal misoprostol.
    Gastroenterology, 1991, Volume: 101, Issue:1

    Topics: Acetates; Alprostadil; Animals; Calcium Gluconate; Caseins; Cell Membrane Permeability; Chromium Radioisotopes; Drug Synergism; Edetic Acid; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Histamine; Histamine Antagonists; Hydrogen-Ion Concentration; Indomethacin; Intestine, Small; Male; Misoprostol; Rabbits; Serum Albumin, Bovine; Thiocyanates

1991
Arachidonic acid metabolism and casein secretion in lactating rabbit mammary epithelial cells: effects of inhibitors of prostaglandins and leukotrienes synthesis.
    Prostaglandins, 1988, Volume: 35, Issue:2

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Caffeic Acids; Caseins; Cyclooxygenase Inhibitors; Dinoprost; Docosahexaenoic Acids; Epithelium; Female; Glutathione Transferase; Indomethacin; Lactation; Leukotriene B4; Lipoxygenase Inhibitors; Mammary Glands, Animal; Masoprocol; Pregnancy; Prolactin; Prostaglandins F; Rabbits; SRS-A

1988
Stimulation of prostaglandin synthesis in cultured rat synovial cells by a factor derived from polymorphonuclear leukocytes.
    Prostaglandins, 1984, Volume: 27, Issue:5

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Caseins; Cell Extracts; Cells, Cultured; Dexamethasone; Dinoprostone; Indomethacin; Male; Microbial Collagenase; Molecular Weight; Neutrophils; Prostaglandins E; Rats; Rats, Inbred Lew; Synovial Fluid; Time Factors; Tissue Extracts

1984
[Role of prostaglandins in the mechanism of action of preparations for parenteral nitrogen feeding].
    Gematologiia i transfuziologiia, 1983, Volume: 28, Issue:10

    Topics: Amino Acids; Animals; Caseins; Dinoprostone; Free Radicals; Indomethacin; Liver; Male; Muscles; Nitrogen; Parenteral Nutrition; Prostaglandins E; Prostaglandins E, Synthetic; Protein Deficiency; Rats

1983
Changes in natural killer activities in experimental secondary amyloidosis.
    Scandinavian journal of immunology, 1984, Volume: 19, Issue:6

    Topics: Amyloid; Amyloidosis; Animals; Caseins; Cell Adhesion; Immune Tolerance; Indomethacin; Killer Cells, Natural; Lymphocyte Depletion; Mice; Mice, Inbred C3H; Mice, Inbred CBA; Spleen

1984
[Effect of indomethacin on the lactogenic action of prolactin].
    Biochimie, 1980, Volume: 62, Issue:7

    Topics: Animals; Caseins; Female; Hydrocortisone; Indomethacin; Insulin; Kinetics; Lactose Synthase; Mammary Glands, Animal; Organ Culture Techniques; Prolactin; Prostaglandins E; Prostaglandins F; Pseudopregnancy; Rabbits

1980
Flow-cytometric analysis of oxidative and proteolytical activities in tissue-associated phagocytes from normal and hypertrophic muscles.
    Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology, 1995, Volume: 9, Issue:4

    Topics: Animals; Caseins; Cattle; Endopeptidases; Flow Cytometry; Hydrolysis; Hypertrophy; Indomethacin; Male; Muscles; Norepinephrine; Oxidation-Reduction; Phagocytes; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide

1995
Inhibition of proteolysis by a cyclooxygenase inhibitor, indomethacin.
    Neurochemical research, 2000, Volume: 25, Issue:11

    Topics: Animals; Calpain; Caseins; Cyclooxygenase Inhibitors; Hydrolysis; Indomethacin; Rats; Rats, Sprague-Dawley; Spinal Cord

2000
Vasodilation to vascular endothelial growth factor in the uterine artery of the pregnant rat is blunted by low dietary protein intake.
    Pediatric research, 2002, Volume: 51, Issue:4

    Topics: Acetylcholine; Animals; Arteries; Body Weight; Cardiovascular Agents; Caseins; Dietary Proteins; Dose-Response Relationship, Drug; Endothelial Growth Factors; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Indomethacin; Intercellular Signaling Peptides and Proteins; Lymphokines; NG-Nitroarginine Methyl Ester; Potassium Chloride; Pregnancy; Protein Deficiency; Random Allocation; Rats; Rats, Wistar; Regional Blood Flow; Uterus; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasodilation; Vasodilator Agents

2002
Enzyme-modified cheese exerts inhibitory effects on allergen permeation in rats suffering from indomethacin-induced intestinal inflammation.
    Bioscience, biotechnology, and biochemistry, 2008, Volume: 72, Issue:7

    Topics: Allergens; Amino Acid Sequence; Animals; Caco-2 Cells; Caseins; Cell Membrane Permeability; Cheese; Disease Models, Animal; Enzymes; Food Hypersensitivity; Humans; Indomethacin; Inflammation; Intestinal Absorption; Intestines; Peptide Fragments; Rats

2008
Skimmed, sterilized, and concentrated bovine late colostrum promotes both prevention and recovery from intestinal tissue damage in mice.
    Journal of dairy science, 2013, Volume: 96, Issue:3

    Topics: Animals; Caseins; Cattle; Colostrum; Female; Indomethacin; Intestinal Mucosa; Intestine, Small; Intestines; Mice; Mice, Inbred BALB C; Milk Proteins; Whey Proteins

2013
Enhancement of water solubility of indomethacin by complexation with protein hydrolysate.
    International journal of pharmaceutics, 2013, Sep-10, Volume: 453, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Caseins; Indomethacin; Protein Hydrolysates; Solubility; Water

2013
Protective effects of β-casofensin, a bioactive peptide from bovine β-casein, against indomethacin-induced intestinal lesions in rats.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:4

    Topics: Administration, Oral; Animals; Caseins; Cattle; Enteritis; HT29 Cells; Humans; Indomethacin; Intestinal Mucosa; Intestines; Jejunal Diseases; Male; Peptide Fragments; Protective Agents; Rats, Wistar; Wound Healing

2016
Glycomacropeptide Ameliorates Indomethacin-Induced Enteropathy in Rats by Modifying Intestinal Inflammation and Oxidative Stress.
    Molecules (Basel, Switzerland), 2020, May-18, Volume: 25, Issue:10

    Topics: Animals; Caseins; Chemokine CXCL1; Disease Models, Animal; Gene Expression Regulation; Humans; Indomethacin; Inflammation; Interleukin-1beta; Intestinal Mucosa; Milk Proteins; Mucin-2; Nitric Oxide Synthase Type II; Oxidative Stress; Peptide Fragments; Protein-Losing Enteropathies; Rats

2020