Page last updated: 2024-09-04

caseins and genistein

caseins has been researched along with genistein in 24 studies

Compound Research Comparison

Studies
(caseins)
Trials
(caseins)
Recent Studies (post-2010)
(caseins)
Studies
(genistein)
Trials
(genistein)
Recent Studies (post-2010) (genistein)
16,8635614,1707,4232042,311

Protein Interaction Comparison

ProteinTaxonomycaseins (IC50)genistein (IC50)
Chain A, Estrogen receptor 1 (alpha)Homo sapiens (human)0.009
Maltase-glucoamylase, intestinalHomo sapiens (human)2.61
Steroid hormone receptor ERR2Homo sapiens (human)0.395
Tyrosine-protein kinase ABL1Homo sapiens (human)5.5
Epidermal growth factor receptorHomo sapiens (human)1.2
TransthyretinHomo sapiens (human)7.8
Estrogen receptorHomo sapiens (human)1.3477
Steroid hormone receptor ERR1Homo sapiens (human)0.01
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)9.033
17-beta-hydroxysteroid dehydrogenase type 1Homo sapiens (human)2.21
Protein kinase C alpha typeHomo sapiens (human)1
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)1
Amine oxidase [flavin-containing] AHomo sapiens (human)4.184
Thromboxane-A synthase Homo sapiens (human)7.72
Amine oxidase [flavin-containing] BHomo sapiens (human)3.9333
Dipeptidyl peptidase 4Homo sapiens (human)0.48
Proteasome subunit beta type-5Homo sapiens (human)9.26
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.395
Tyrosine-protein kinase CSKHomo sapiens (human)1
Dual specificity mitogen-activated protein kinase kinase 4Homo sapiens (human)0.4
Xanthine dehydrogenase/oxidaseBos taurus (cattle)1.73
Aldehyde oxidaseHomo sapiens (human)0.34
Integrase Human immunodeficiency virus 11.1
Estrogen receptor betaHomo sapiens (human)0.3706
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)Plasmodium falciparum (malaria parasite P. falciparum)7
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)3.8905
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)7.85
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)9.1201

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (20.83)18.2507
2000's12 (50.00)29.6817
2010's7 (29.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fan, G; Rillema, JA1
Bissell, MJ; Desprez, PY; Roskelley, CD1
Gouilleux, F; Groner, B; Mundt, M; Wakao, H1
Adlercreutz, H; Gooderham, MH; Holub, BJ; Ojala, ST; Wähälä, K1
Holub, BJ; Ogborn, MR; Philbrick, DJ; Takahashi, H; Tomobe, K1
Hanson, L; McManaman, JL; Neville, MC; Wright, RM1
Breitkopf, NP; Eyster, KM; Martin, DS; Williams, JL1
Besch-Williford, C; Day, JK; Hufford, MG; Lubahn, DB; MacDonald, RS; McMann, TR1
Bennink, M; Browning, JD; Constantinou, A; Guo, JY; Li, X; Lubahn, DB; MacDonald, RS; Rottinghaus, GE1
Curran, EM; Estes, DM; Franklin, C; Judy, BM; Lubahn, DB; Macdonald, RS; Newton, LG; Rottinghaus, GE1
Bélanger, S; Deschepper, CF; Picard, S; Souzeau, E1
Daniel, H; Erhard, P; Fuchs, D; Rimbach, G; Wenzel, U1
Badger, TM; Chatman, L; Eason, RR; Geng, Y; Gu, L; Simmen, FA; Simmen, RC; Till, SR; Velarde, MC1
Simmen, FA; Simmen, RC; Su, Y; Xiao, R1
Badger, TM; Hennings, LJ; Simmen, FA; Xiao, R1
Badger, TM; Ronis, MJ; Singhal, R1
Badeaux, J; Badger, TM; Chen, Y; Ronis, MJ1
Bowman, MT; Greenway, AD; Huang, SA; Kang, P; Mercado, CP; Prior, RL; Simmen, FA; Zavacki, AM1
Bariyanga, J; Bourassa, P; Tajmir-Riahi, HA1
Anjani, G; Asakawa, T; Ohta, A; Yasuhara, K1
Fu, Y; Wang, S; Zhao, XH1
Kobayashi, K; Matsunaga, K; Nishimura, T; Suzuki, T; Tsugami, Y2
Han, A; Kwon, YH; Won, SB1

Trials

1 trial(s) available for caseins and genistein

ArticleYear
A soy protein isolate rich in genistein and daidzein and its effects on plasma isoflavone concentrations, platelet aggregation, blood lipids and fatty acid composition of plasma phospholipid in normal men.
    The Journal of nutrition, 1996, Volume: 126, Issue:8

    Topics: Adult; Caseins; Cholesterol; Cholesterol, HDL; Collagen; Estrogens, Non-Steroidal; Fatty Acids; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Isoflavones; Lipids; Male; Phospholipids; Phytoestrogens; Plant Preparations; Plant Proteins, Dietary; Platelet Aggregation; Soybean Proteins

1996

Other Studies

23 other study(ies) available for caseins and genistein

ArticleYear
Effect of a tyrosine kinase inhibitor, genistein, on the actions of prolactin in cultured mouse mammary tissues.
    Molecular and cellular endocrinology, 1992, Volume: 83, Issue:1

    Topics: Animals; Caseins; Cells, Cultured; Cyclic AMP; Enzyme Activation; Female; Genistein; Isoflavones; Lactose; Lipids; Mammary Glands, Animal; Mice; Ornithine Decarboxylase; Pregnancy; Prolactin; Protein-Tyrosine Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases

1992
Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Dec-20, Volume: 91, Issue:26

    Topics: Animals; Caseins; Cell Aggregation; Cells, Cultured; Extracellular Matrix; Female; Gene Expression Regulation, Developmental; Genistein; In Vitro Techniques; Integrins; Isoflavones; Mice; Phosphotyrosine; Prolactin; Receptor Aggregation; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine

1994
Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription.
    The EMBO journal, 1994, Sep-15, Volume: 13, Issue:18

    Topics: Alkaloids; Amino Acid Sequence; Animals; Caseins; Cells, Cultured; DNA; DNA-Binding Proteins; Genistein; Isoflavones; Janus Kinase 2; Milk Proteins; Models, Molecular; Molecular Sequence Data; Phosphorylation; Prolactin; Protein Binding; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Prolactin; Recombinant Proteins; Signal Transduction; STAT5 Transcription Factor; Staurosporine; Trans-Activators; Transcription, Genetic; Transcriptional Activation; Transfection; Tyrosine

1994
Effect of dietary soy protein and genistein on disease progression in mice with polycystic kidney disease.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1998, Volume: 31, Issue:1

    Topics: Animals; Caseins; Diet, Protein-Restricted; Disease Progression; Genistein; Kidney; Male; Mice; Mice, Inbred Strains; Polycystic Kidney Diseases; Soybean Proteins

1998
Lactogenic hormones regulate xanthine oxidoreductase and beta-casein levels in mammary epithelial cells by distinct mechanisms.
    Archives of biochemistry and biophysics, 2000, Jan-15, Volume: 373, Issue:2

    Topics: Animals; Caseins; Cell Line; Enzyme Induction; Epidermal Growth Factor; Female; Flavonoids; Genistein; Hydrocortisone; Mammary Glands, Animal; Mice; Mitogen-Activated Protein Kinases; Prolactin; RNA, Messenger; Signal Transduction; Time Factors; Xanthine Dehydrogenase

2000
Dietary soy exerts an antihypertensive effect in spontaneously hypertensive female rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 281, Issue:2

    Topics: Animals; Blood Pressure; Caseins; Chlorisondamine; Diet; Enzyme Inhibitors; Female; Ganglionic Blockers; Genistein; Glycine max; Heart Rate; Hypertension; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ovariectomy; Physical Stimulation; Rats; Rats, Inbred SHR; Rats, Inbred WKY

2001
Dietary genistein increased DMBA-induced mammary adenocarcinoma in wild-type, but not ER alpha KO, mice.
    Nutrition and cancer, 2001, Volume: 39, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Caseins; Diet; Estradiol; Estrogen Receptor alpha; Female; Genistein; Insulin-Like Growth Factor I; Male; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Size; Ovary; Receptors, Estrogen; Skin Neoplasms; Uterus; Weight Gain

2001
Dietary soy isoflavones and estrone protect ovariectomized ERalphaKO and wild-type mice from carcinogen-induced colon cancer.
    The Journal of nutrition, 2004, Volume: 134, Issue:1

    Topics: Animals; Azoxymethane; Carcinogens; Caseins; Colonic Neoplasms; Diet; Estrogen Receptor alpha; Estrone; Genistein; Glycine max; Isoflavones; Mice; Mice, Knockout; Ovariectomy; Receptors, Estrogen; Soybean Proteins

2004
Dietary soy phytoestrogens and ERalpha signalling modulate interferon gamma production in response to bacterial infection.
    Clinical and experimental immunology, 2004, Volume: 135, Issue:2

    Topics: Animals; Caseins; Chromatography, High Pressure Liquid; Colony Count, Microbial; Dietary Supplements; Enzyme Inhibitors; Genistein; Glycine max; Immunity, Cellular; Immunosuppressive Agents; Interferon-gamma; Interleukin-12; Interleukin-18; Isoflavones; Mice; Mice, Inbred C57BL; Mycobacterium avium; Phytoestrogens; Plant Preparations; Receptors, Estrogen; Signal Transduction; Spleen; Tuberculosis

2004
Dietary isoflavones during pregnancy and lactation provide cardioprotection to offspring rats in adulthood.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 289, Issue:2

    Topics: Animals; Cardiotonic Agents; Caseins; Cell Size; Diet; Dietary Supplements; Female; Genistein; Glycine max; Isoflavones; Lactation; Myocytes, Cardiac; Phytoestrogens; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred WKY

2005
Genistein blocks homocysteine-induced alterations in the proteome of human endothelial cells.
    Proteomics, 2005, Volume: 5, Issue:11

    Topics: Apoptosis; Caseins; Cells, Cultured; Electrophoresis, Gel, Two-Dimensional; Endothelial Cells; Gene Expression Regulation; Genistein; Homocysteine; Humans; Oxidative Stress; Protein Hydrolysates; Proteins; Proteome; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2005
Uterine phenotype of young adult rats exposed to dietary soy or genistein during development.
    The Journal of nutritional biochemistry, 2005, Volume: 16, Issue:10

    Topics: Animals; Apoptosis; Caseins; Diet; Endometrium; Epithelium; Estradiol; Estrogens; Female; Genistein; Glycine max; Myometrium; Phenotype; Progesterone; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Soybean Proteins; Uterus

2005
Expression profiling of rat mammary epithelial cells reveals candidate signaling pathways in dietary protection from mammary tumors.
    Physiological genomics, 2007, Jun-19, Volume: 30, Issue:1

    Topics: Animals; Caseins; Cells, Cultured; Cluster Analysis; Epithelial Cells; Female; Gene Expression Profiling; Gene Expression Regulation; Genistein; Immunohistochemistry; Male; Mammary Glands, Animal; Methylnitrosourea; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; Receptor, Notch2; Signal Transduction; Soybean Proteins; Wnt Proteins; Wnt-5a Protein

2007
Fetal programming of colon cancer in adult rats: correlations with altered neonatal growth trajectory, circulating IGF-I and IGF binding proteins, and testosterone.
    The Journal of endocrinology, 2007, Volume: 195, Issue:1

    Topics: Animals; Animals, Newborn; Azoxymethane; Biomarkers; Caseins; CD3 Complex; Colon; Colonic Neoplasms; Diet; Female; Gene Expression; Genistein; Glucose; Glucose Transporter Type 1; Growth; Insulin; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Intestinal Mucosa; Leptin; Male; Models, Animal; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; RNA, Messenger; Soybean Proteins; Testosterone

2007
Rats fed soy protein isolate (SPI) have impaired hepatic CYP1A1 induction by polycyclic aromatic hydrocarbons as a result of interference with aryl hydrocarbon receptor signaling.
    Toxicology and applied pharmacology, 2008, Mar-01, Volume: 227, Issue:2

    Topics: Animals; Blotting, Western; Caseins; Chromatin; Cytochrome P-450 CYP1A1; Diet; DNA; Enzyme Induction; Estrogens, Non-Steroidal; Female; Genistein; Immunoprecipitation; Isoflavones; Liver; Microscopy, Fluorescence; Polycyclic Aromatic Hydrocarbons; Rats; Receptors, Aryl Hydrocarbon; RNA; Signal Transduction; Soybean Proteins

2008
Dietary soy protein isolate attenuates metabolic syndrome in rats via effects on PPAR, LXR, and SREBP signaling.
    The Journal of nutrition, 2009, Volume: 139, Issue:8

    Topics: Animals; Anticholesteremic Agents; Caseins; Cholesterol; Dietary Fats; DNA-Binding Proteins; Fatty Liver; Female; Gene Expression; Genistein; Hypercholesterolemia; Insulin Resistance; Isoflavones; Lipid Metabolism; Liver X Receptors; Male; Metabolic Syndrome; Orphan Nuclear Receptors; PPAR alpha; PPAR gamma; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Signal Transduction; Soybean Proteins; Sterol Regulatory Element Binding Protein 1; Weight Gain

2009
Soy protein diet alters expression of hepatic genes regulating fatty acid and thyroid hormone metabolism in the male rat.
    The Journal of nutritional biochemistry, 2010, Volume: 21, Issue:11

    Topics: Animals; Caseins; Diet; Fatty Acids; Female; Gene Expression Regulation; Genistein; Iodide Peroxidase; Isoflavones; Lipid Metabolism; Liver; Male; PPAR alpha; Pregnancy; Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, Thyroid Hormone; RNA, Messenger; Soybean Proteins; Thyroid Hormones

2010
Binding sites of resveratrol, genistein, and curcumin with milk α- and β-caseins.
    The journal of physical chemistry. B, 2013, Feb-07, Volume: 117, Issue:5

    Topics: Animals; Antioxidants; Binding Sites; Caseins; Curcumin; Genistein; Milk; Molecular Docking Simulation; Protein Stability; Protein Structure, Secondary; Resveratrol; Spectrum Analysis; Stilbenes; Water

2013
Solubilization of genistein by caseinate micellar system.
    Journal of oleo science, 2014, Volume: 63, Issue:4

    Topics: Anilino Naphthalenesulfonates; Caseins; Chromatography, High Pressure Liquid; Cryoelectron Microscopy; Electron Microscope Tomography; Fluorescent Dyes; Freezing; Genistein; Hydrophobic and Hydrophilic Interactions; Micelles; Microscopy, Atomic Force; Particle Size; Phase Transition; Protein Interaction Domains and Motifs; Solubility; Solutions; Water

2014
The Cooperative Effect of Genistein and Protein Hydrolysates on the Proliferation and Survival of Osteoblastic Cells (hFOB 1.19).
    Molecules (Basel, Switzerland), 2016, Nov-08, Volume: 21, Issue:11

    Topics: Apoptosis; Caseins; Cell Cycle; Cell Line; Cell Proliferation; Cell Survival; Drug Synergism; Gelatin; Genistein; Humans; Hydrolysis; Osteoblasts; Soybean Proteins

2016
Isoflavones and their metabolites influence the milk component synthesis ability of mammary epithelial cells through prolactin/STAT5 signaling.
    Molecular nutrition & food research, 2017, Volume: 61, Issue:10

    Topics: Animals; Caseins; Cells, Cultured; Coumestrol; Epithelial Cells; Female; Genistein; Isoflavones; Mammary Glands, Animal; Mice; Mice, Inbred ICR; Milk; Phenols; Phosphorylation; Phytoestrogens; Prolactin; STAT5 Transcription Factor

2017
Different Effects of Maternal Low-Isoflavone Soy Protein and Genistein Consumption on Hepatic Lipid Metabolism of 21-Day-Old Male Rat Offspring.
    Nutrients, 2017, Sep-20, Volume: 9, Issue:9

    Topics: Adiponectin; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Blood Glucose; Caseins; Cholesterol; Dietary Supplements; Fatty Acids, Nonesterified; Female; Genistein; Homocysteine; Insulin; Isoflavones; Lipid Metabolism; Liver; Male; Maternal Nutritional Physiological Phenomena; PPAR alpha; Pregnancy; Rats; Rats, Sprague-Dawley; Soybean Proteins; Triglycerides; Triiodothyronine

2017
Phytoestrogens Weaken the Blood-Milk Barrier in Lactating Mammary Epithelial Cells by Affecting Tight Junctions and Cell Viability.
    Journal of agricultural and food chemistry, 2017, Dec-20, Volume: 65, Issue:50

    Topics: Animals; Caseins; Cell Survival; Coumestrol; Epithelial Cells; Female; Genistein; Humans; Isoflavones; Lactation; Mammary Glands, Animal; Mice; Mice, Inbred ICR; Milk; Phytoestrogens; Tight Junctions

2017