casein-kinase-ii and aurone

casein-kinase-ii has been researched along with aurone* in 1 studies

Other Studies

1 other study(ies) available for casein-kinase-ii and aurone

Article	Year
Flavone inspired discovery of benzylidenebenzofuran-3(2H)-ones (aurones) as potent inhibitors of human protein kinase CK2. Bioorganic chemistry, 2020, Volume: 102 In this work, we describe the design, synthesis and SAR studies of 2-benzylidenebenzofuran-3-ones (aurones), a new family of potent inhibitors of CK2. A series of aurones have been synthesized. These compounds are structurally related to the synthetic flavones and showed nanomolar activities towards CK2. Biochemical tests revealed that 20 newly synthesized compounds inhibited CK2 with IC Topics: Benzofurans; Casein Kinase II; Flavones; Humans; Molecular Docking Simulation; Structure-Activity Relationship	2020

Article

Year

Flavone inspired discovery of benzylidenebenzofuran-3(2H)-ones (aurones) as potent inhibitors of human protein kinase CK2.

Bioorganic chemistry, 2020, Volume: 102

In this work, we describe the design, synthesis and SAR studies of 2-benzylidenebenzofuran-3-ones (aurones), a new family of potent inhibitors of CK2. A series of aurones have been synthesized. These compounds are structurally related to the synthetic flavones and showed nanomolar activities towards CK2. Biochemical tests revealed that 20 newly synthesized compounds inhibited CK2 with IC

Topics: Benzofurans; Casein Kinase II; Flavones; Humans; Molecular Docking Simulation; Structure-Activity Relationship

2020