casein-kinase-ii has been researched along with 4-cresol* in 1 studies
1 other study(ies) available for casein-kinase-ii and 4-cresol
Article | Year |
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Knockdown of CK2α reduces
Renal fibrosis is one of the main causes of chronic kidney disease. Many studies have focused on fibroblasts and myofibroblasts involved in renal fibrogenesis. Recently, several studies have reported that renal proximal tubule epithelial cells are possible initiators of renal fibrosis. However, the mechanism through which cells induce renal fibrosis is poorly understood. In this study, we found that CK2α induces fibrosis in renal proximal tubule epithelial cells (TH1) by regulating the expression of profilin-1 (Pfn1). CKD mouse model and TH1 cells treated with Topics: Adenine; Animals; Casein Kinase II; Cell Line; Cellular Senescence; Cresols; Disease Models, Animal; Epithelial Cells; Fibrosis; Gene Knockdown Techniques; Humans; Kidney Tubules, Proximal; Male; Profilins; Renal Insufficiency, Chronic | 2020 |