caryophyllene-oxide and linalool

This study aimed to investigate the chemical composition of essential oils isolated from Acca sellowiana (feijoa) leaves and stems and elaborate on their relevance as natural anti-aging, coupled with molecular-docking studies. The isolated oils were analysed using gas chromatography-mass spectrometry analysis and investigated for inhibitory effects against acetylcholinesterase, β-secretase, collagenase, elastase and tyrosinase. Molecular-modelling study was performed using MOE-Dock program to evaluate binding interactions of major components with the above-mentioned targets. The leaf oil revealed the predominance of caryophyllene oxide (24.3 %), linalool (7.9 %), and spathulenol (6.6 %), while the stem oil was presented by caryophyllene oxide (38.1 %), α-zingiberene (10.1 %) and humulene oxide II (6.0 %). The stem oil expressed superior inhibitory activities against acetylcholinesterase (IC

Topics: Acetylcholinesterase; Acyclic Monoterpenes; Amyloid Precursor Protein Secretases; Feijoa; Molecular Docking Simulation; Monocyclic Sesquiterpenes; Monophenol Monooxygenase; Oils, Volatile; Oxides; Pancreatic Elastase; Plant Leaves; Polycyclic Sesquiterpenes; Sesquiterpenes; Terpenes

Odorant binding proteins (OBPs) play an important role in insect peripheral olfactory systems and exploring the physiological function of OBPs could facilitate the understanding of insects' chemical communication. Here, the functional analysis of an antenna-based NlugOBP8 from brown planthopper (BPH)

Topics: Animals; Hemiptera; Oryza; Perception; Terpenes

In this study, the essential oil composition of

Topics: Acyclic Monoterpenes; Cymenes; Gas Chromatography-Mass Spectrometry; Lamiaceae; Oils, Volatile; Polycyclic Sesquiterpenes

The chemical composition, and antioxidant activity of the essential oils of the endemic

Topics: Acyclic Monoterpenes; Antioxidants; Gas Chromatography-Mass Spectrometry; Oils, Volatile; Phlomis; Polycyclic Sesquiterpenes; Sesquiterpenes; Turkey

The chemical composition of the essential oil (EO) obtained from the aerial parts of Rydingia michauxii (Briq.) Scheen & V.A. Albert was analysed by gas chromatography and gas chromatography/mass spectrometry (GC/MS). Eighty components were identified in the oil with caryophyllene oxide (20.1%), trans-verbenol (10.2%), linalool (5.3%) and humulene epoxide II (4.6%) as main constituents. We reported here the chemical compositions of R. michauxii EOs from southern Zagros of Iran with a distinct chemical profile for the first time.

Topics: Acyclic Monoterpenes; Bicyclic Monoterpenes; Gas Chromatography-Mass Spectrometry; Iran; Lamiaceae; Monocyclic Sesquiterpenes; Monoterpenes; Oils, Volatile; Polycyclic Sesquiterpenes; Sesquiterpenes

Micromeria persica Boiss. is medicinal and aromatic plant, belonging to the Lamiaceae family. The chemical composition of the essential oils (EOs) from aerial parts of M. persica were extracted using hydro-distillation method and analysed using GC and GC-MS. Fifty-two compounds were identified in the EOs of aerial parts of M. persica. The main chemical compositions were n-hexadecanoic acid (14.9%), thymol (9.5%), linoleic acid (8.0%), carvacrol (5.6%), (E)-nerolidol (5.5%), linolenic acid (5.5%), α-cadinol (2.7%), linalool (2.7%), borneol (2.6%), caryophyllene oxide (2.3%) and pulegone (2.0%). Presence of borneol, thymol, carvacrol and pulegone suggests the potential of this plant as a flavouring source in the food industry, being used in perfumery and cosmetics industry, vitamin E synthesis and exhibit strong fungicidal, antibacterial and antimicrobial activities.

Topics: Acyclic Monoterpenes; Camphanes; Cyclohexane Monoterpenes; Cymenes; Gas Chromatography-Mass Spectrometry; Iran; Lamiaceae; Monoterpenes; Oils, Volatile; Plant Components, Aerial; Polycyclic Sesquiterpenes; Sesquiterpenes; Terpenes; Thymol

This paper reports on the compounds identified in the leaf and flower essential oils obtained by hydrodistillation of Plumeria alba L. (Apocynaceae) grown in Nigeria. The chemical analysis of the essential oils was achieved by means of gas chromatography (GC) and gas chromatography coupled with mass spectrometry (GC-MS). Linalool (13.2%), n-nonanal (9.6%), phenyl acetaldehyde (8.5%), neryl acetone (5.3%) and n-decanal (5.1%) were the main constituents of the leaf oil. On the other hand, the flower oil comprised mainly of limonene (9.1%), linalool (7.9%), α-cedrene (8.0%), caryophyllene oxide (7.9%) and (E, E)-α-farnesene (6.6%). This is the first report on the essential oil constituents of P. alba.

Topics: Acyclic Monoterpenes; Apocynaceae; Cyclohexenes; Flowers; Gas Chromatography-Mass Spectrometry; Limonene; Monoterpenes; Nigeria; Oils, Volatile; Plant Leaves; Polycyclic Sesquiterpenes; Sesquiterpenes; Terpenes

The essential oil composition of the aerial parts of Nepeta erecta Benth. (Family: Lamiaceae) from Uttarakhand, India was analysed by capillary gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). A total of 34 constituents were identified representing 94.6% of the oil composition. Oxygenated monoterpenes (74.0%) constituted the major proportion of the oil, dominated by isoiridomyrmecin (70.6%) as a single major constituent. Other significant constituents were caryophyllene oxide (9.6%), β-Bourbonene (2.0%), humulene epoxide II (1.7%) and linalool (1.0%). The in vitro antioxidant activity (AOA) was assessed using β-Carotene bleaching assay, reducing power, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and inhibition of lipid peroxidation methods. The oil was found to exhibit AOA by inhibiting β-Carotene bleaching (54.6 ± 2.52%) and by scavenging DPPH free radical (IC(50) = 0.74 ± 0.12 mg mL(-1)). The AOA of the essential oil of N. erecta and its major compound isoiridomyrmecin has not been reported so far.

Topics: Acyclic Monoterpenes; Antioxidants; Biphenyl Compounds; Chromatography, Gas; Gas Chromatography-Mass Spectrometry; India; Iridoids; Molecular Structure; Monoterpenes; Nepeta; Oils, Volatile; Picrates; Polycyclic Sesquiterpenes; Sesquiterpenes

Citrus aurantium leaves' essential oils (EOs) were evaluated for chemical composition and antioxidant and antibacterial activities. The vegetable material, taken 5 times during the year, has undergone the hydrodistillation to prepare EO. Chemical characterization by gas chromatography/mass spectrometry and GC/flame ionization detection allowed the identification of 46 compounds, and a notable quantitative and qualitative differences between the different Petitgrain samples according to the harvest time. Linalool (43.2% to 65.97%), linalyl acetate (0.77% to 24.77%), and α-terpineol (9.29% to 12.12%) were the main components. The most important number of components was registered for summer EOs (July and September). The 5 EOs submitted biological activities screening, namely, antioxidant and antimicrobial activities. Weak antioxidant activities (IC(50) values >10000 mg/L) were registered by both 1,1-diphenyl-2-picrylhydrazyl and 2,2'-azinobis-3-ethylbenzothiazoline-6-sulphonate assays, mostly because the weak amount of phenols in EOs. Antibacterial activities (12 microorganisms) were registered against Gram-positive bacteria [Bacillus subtilis (MIC = 2.7 mg/mL), Staphylococcus aureus (4.8 mg/mL)], and moderated ones against yeasts [Saccharomyces cerevisiae (9.2 mg/mL)] and fungi [Mucor ramannianus (5 mg/mL)]. Positive correlations between the identified compounds and the antimicrobial activities were noted. Many compounds were correlated to antimicrobial activity mainly caryophyllene oxide against Escherichia coli (R(2) = 0.99), S. cerevisiae (R(2) = 0.99), and Fusarium culmorum (R(2) = 0.99).

Topics: Acyclic Monoterpenes; Anti-Infective Agents; Antioxidants; Bacillus subtilis; Biphenyl Compounds; Citrus; Cyclohexane Monoterpenes; Cyclohexenes; Escherichia coli; Flame Ionization; Food Contamination; Food Microbiology; Fusarium; Gas Chromatography-Mass Spectrometry; Microbial Sensitivity Tests; Monoterpenes; Mucor; Oils, Volatile; Picrates; Plant Leaves; Polycyclic Sesquiterpenes; Saccharomyces cerevisiae; Seasons; Sesquiterpenes; Staphylococcus aureus

To study the chemical constituents, antimicrobial activity and antitumor activity of the essential oil from Zanthoxylum avicennae.. The essential oil from the leaves of Zanthoxylum avicennae was extracted by steam distillation. The components of the essential oil were separated and identified by GC-MS.. 72 components were identified and accounted for 98.15% of the all peak area. The essential oil exhibited strong antitumor activity against K-562 human tumor cell lines with IC50 of 1.76 microg/mL. It also exhibited moderate antimicrobial activity against three bacteria.. The essential oil of Zanthoxylum avicennae contains various active constituents. This result provides scientific reference for the pharmacological further research of Zanthoxylum avicennae.

Topics: Acyclic Monoterpenes; Anti-Infective Agents; Antineoplastic Agents, Phytogenic; Bacteria; Cell Line, Tumor; Gas Chromatography-Mass Spectrometry; Humans; Inhibitory Concentration 50; Monoterpenes; Oils, Volatile; Plant Leaves; Polycyclic Sesquiterpenes; Sesquiterpenes; Zanthoxylum