caryophyllene-oxide has been researched along with citral* in 2 studies
2 other study(ies) available for caryophyllene-oxide and citral
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Pharmacological and neuroprotective profile of an essential oil derived from leaves of Aloysia citrodora Palau.
The Jordanian 'Melissa', (Aloysia citrodora) has been poorly studied both pharmacologically and in the clinic. Essential oils (EO) derived from leaves of A. citrodora were obtained by hydrodistillation, analysed by gas chromatography-mass spectrometry (GC-MS) and were investigated for a range of neurobiological and pharmacological properties, as a basis for potential future use in drug discovery.. A selection of central nervous system (CNS) receptor-binding profiles was carried out. Antioxidant activity and ferrous iron-chelating assays were adopted, and the neuroprotective properties of A. citrodora EO assessed using hydrogen peroxide-induced and β-amyloid-induced neurotoxicity with the CAD (Cath.-a-differentiated) neuroblastoma cell line.. The major chemical components detected in the A. citrodora EOs, derived from dried and fresh leaves, included limonene, geranial, neral, 1, 8-cineole, curcumene, spathulenol and caryophyllene oxide, respectively. A. citrodora leaf EO inhibited [(3) H] nicotine binding to well washed rat forebrain membranes, and increased iron-chelation in vitro. A. citrodora EO displays effective antioxidant, radical-scavenging activities and significant protective properties vs both hydrogen peroxide- and β-amyloid-induced neurotoxicity.. A. citrodora EO displays a range of pharmacological properties worthy of further investigation to isolate the compounds responsible for the observed neuroactivities, to further analyse their mode of action and determine their clinical potential in neurodegenerative diseases. Topics: Acyclic Monoterpenes; Animals; Antioxidants; Cell Line, Tumor; Cyclohexanols; Cyclohexenes; Eucalyptol; Free Radical Scavengers; Limonene; Monoterpenes; Neuroblastoma; Neuroprotective Agents; Oils, Volatile; Palau; Plant Leaves; Plant Oils; Polycyclic Sesquiterpenes; Prosencephalon; Rats; Sesquiterpenes; Terpenes; Verbenaceae | 2015 |
Fumigant toxicity of lemon eucalyptus oil constituents to acaricide-susceptible and acaricide-resistant Tetranychus urticae.
This study was aimed at assessing the fumigant toxicity of 14 essential oil constituents from lemon eucalyptus, Eucalyptus citriodora Hook, and another ten known compounds to females of acaricide-susceptible, chlorfenapyr-resistant, fenpropathrin-resistant, pyridaben-resistant and abamectin-resistant strains of Tetranychus urticae Koch.. Menthol (LC(50) , 12.9 µg cm(-3) ) was the most toxic compound, followed by citronellyl acetate (16.8 µg cm(-3) ), against the susceptible females. High toxicity was also produced by β-citronellol, citral, geranyl acetate and eugenol (LC(50) , 21.7-24.6 µg cm(-3) ). The fumigant toxicity of these compounds was almost identical against females from either of the susceptible and resistant strains, indicating that the compounds and acaricides do not share a common mode of action or elicit cross-resistance.. Global efforts to reduce the level of highly toxic synthetic acaricides in the agricultural environment justify further studies on materials derived from lemon eucalyptus oil, particularly menthol and citronellyl acetate, as potential acaricides for the control of acaricide-resistant T. urticae as fumigants with contact action. Topics: Acaricides; Acetates; Acyclic Monoterpenes; Animals; Eucalyptus; Eugenol; Female; Fumigation; Gas Chromatography-Mass Spectrometry; Insecticide Resistance; Menthol; Monoterpenes; Plant Oils; Terpenes; Tetranychidae; Toxicity Tests | 2011 |